Ceraxon instructions for use, analogues, composition, indicationslogofacebookvkontaktesignsstar-full

Category: Published 04/04/2017 · Comments: · Reading time: 6 min · Views: 5,469

A modern nootropic drug with a wide range of pharmacological effects on the human body is the drug “Ceraxon”. What does the medicine help with? The medication significantly reduces the manifestations of negative neurological symptoms and also restores the membranes of neurocytes. The instructions for use of the drug “Cerakson” prescribe its use for the correction of the consequences of TBI and various forms of strokes. It has proven itself excellently in neurological and traumatological practice.

Instructions for use

Let's study the instructions for use for the drug Ceraxon.

Mode of application

It is worth considering that the method of application depends on the type of substance:

A substance for intravenous administration is used by slowly injecting the medication intravenously (over 3-5 minutes in accordance with the prescribed dose). If the intravenous drip method is used, then the infusion should occur at an infusion rate of 40-60 drops/min. For elderly patients. When prescribing a prescription to elderly patients, no dosage adjustment is required. The Ceraxon product can be used with all types of intravenous isotope and dextrose solutions.
Substance for oral administration. Before use, the medicine can be diluted with water (115-125 ml). The method of administration by injecting the drug into a vein is considered more common than intramuscular administration of the drug. When administering a substance intramuscularly, it is recommended to avoid injecting the drug into an area of muscle tissue that has already been used to administer the drug previously. The substance in the ampoule is used once. After opening the ampoule, the medicine should be used immediately.

Release forms

The drug is available in the form:

Description and composition

Sodium citicoline is used as the main active element of the drug Ceraxon. The dosage of the substance in one unit of the product is determined by the release form. The range of auxiliary elements also differs.

Tablet form: talc, titanium dioxide, castor oil and magnesium stearate, ammonium methacrylate copolymer, microcrystalline cellulose.
Oral solution: glycerin, citric acid, glycerinformal, purified water, sorbitol, sodium citrate and saccharin, food coloring, berry essence, methylparaben, nipazole.
Injection solution: water for injection, sodium hydroxide or hydrochloric acid.

Pharmacological action of the drug Ceraxon

The active component of the drug "Ceraxon" is citicoline, which, having a neotropic effect, has the following spectrum of actions:

restoration of damaged cell membranes;
improvement of transmission (cholinergic) in brain tissue;
reducing the duration of coma (post-traumatic), as well as the severity of various neurological symptoms in injuries (traumatic brain);
preventing the formation of free radicals;
inhibition of the action of phospholipases;
reduction in the volume of brain damage during the acute period of stroke.

The drug "Ceraxon" is also used very effectively in the treatment of motor and sensory disorders of a neurological nature of degenerative and vascular origin. According to the instructions, a person who has suffered chronic cerebral hypoxia can undergo therapy with Ceraxon and receive effective treatment for many cognitive disorders, such as: lack of initiative, difficulty performing the simplest actions that are associated with self-care, memory impairment. In addition, the drug "Ceraxon" increases the level of consciousness and attention and reduces the manifestations of amnesia against the background of the disease.

Indications and contraindications for the use of the drug Ceraxon

Why is Ceraxon prescribed? The drug is used as part of complex therapy in the acute period of ischemic stroke and traumatic brain injury, and in the recovery period of ischemic and hemorrhagic strokes. The drug is effective for cognitive and behavioral disorders in patients suffering from degenerative and vascular diseases of the brain. Ceraxon is used for depression.

Neurologists at the Yusupov Hospital do not use the medicine Ceraxon if there are the following contraindications:

The predominance of the tone of the parasympathetic part of the autonomic nervous system;
Individual hypersensitivity to the ingredients of the drug;
Hereditary pathology associated with glucose intolerance (oral solution).

The drug is not prescribed to children and adolescents under 18 years of age, pregnant and breastfeeding women.

Expert opinion
Author:
Tatyana Aleksandrovna Kosova
Head of the Department of Rehabilitation Medicine, neurologist, reflexologist
Doctors note an increase in the number of diagnosed cerebrovascular diseases. This group of pathologies occupies a leading place among the causes of death. Cerebrovascular diseases are characterized by impaired cognitive function and rapid progression. Ceraxon is part of the complex therapy of these conditions.
Numerous studies prove the effectiveness of the drug. The drug has neuroprotective, neuroplastic and neurotrophic effects. Ceraxon is prescribed to correct the psycho-emotional background. The drug is used as a means of slowing the growth of the ischemic focus during the development of acute cerebrovascular accident. The drug has an equally positive effect both in the treatment of the disease and for preventive purposes. Doctors at the Yusupov Hospital prescribe Ceraxon as part of the treatment for cerebrovascular diseases. Methods of administration, dosage and duration of taking the drug are determined individually. Despite the positive properties of the drug, you should consult your doctor before using it. Self-medication can lead to worsening of the condition.

Overdose and side effects

The drug is absolutely non-toxic; no cases of overdose have been recorded in this regard. Sometimes one of the side effects occurred. In the case of treatment with large dosages and increased duration of use, side effects increase. If undesirable consequences occur, treatment is prescribed according to specific symptoms.

The drug has various undesirable side effects. Most of them are associated with a reaction to the drug from the gastrointestinal tract: nausea, vomiting, loss of appetite, gastrointestinal upset.

The incidence of side effects is very low, one in a thousand. When

such reactions, you should stop taking the drug or replace it with an analogue, but be sure to see a doctor. If all the patient’s characteristics and contraindications were taken into account when prescribing, then the side effects are zero.

With alcohol

Due to the negative effects of ethanol on the body and nervous system, interaction of the drug with alcohol is not recommended. Ceraxon and different doses of alcohol are characterized by low compatibility due to the high probability of reducing the effectiveness of the drug.

To minimize side effects and various complications, it is recommended to refrain from drinking alcoholic beverages during drug therapy. This is especially true for pregnant women (any trimester of pregnancy).

If unusual situations arise, a one-time combination of alcohol and drugs is possible, but drinks must be consumed in compliance with the following intervals:

syrup and solution – 24 hours for men, 32 hours for women;
injections – 15 days after completion of the course of treatment.

The consequences of ignoring the duration of breaks include heart rhythm disturbances, attacks of tachycardia, bradycardia, and orthostatic hypotension.

To relieve anxiety symptoms, you need to stop drinking alcohol and drink more water (especially the first 4-6 hours). If the condition worsens, you should seek qualified help.

Instructions for use

The medication should absolutely not be used with the simultaneous use of drugs whose active substance is meclofenoxate.

The drug has features regarding each method of administration:

Intravenous use involves slowly introducing the medication into the body over 3-5 minutes, based on the dose volume.
When using a dropper, the Ceraxon solution should penetrate the body at 40-60 drops per minute.
The daily dose for adults is 1-4 tablets per day.
When taking the medicine orally, the purchased solution must be diluted with water and a special dosing syringe must be used.

There is no need to adjust the recommended dose of the drug for elderly patients.

The medicine must be taken with meals or between meals. The solution for oral use is diluted in half a glass of water. When administering the drug intramuscularly, each injection is injected into different places to avoid negative consequences.

During treatment with Cerakson, it is necessary to abandon active life activities, since this drug can affect the speed of the body's reaction.

Scheme for using the solution:

Intravenous administration twice a day, 500-1000 mg for two weeks;
After this period, take intramuscularly 2 times a day;
Upon completion, it is recommended to switch to the oral type of treatment.

The maximum effect of therapy is achieved after 3 months.

During the acute period of stroke, use 2 times 1000 ml for a period of 6 weeks. When the condition is restored, the daily dose is 5-10 ml twice a day.

Indications for use

The drug Ceraxon is prescribed in the following situations:

at a critical stage of the course of traumatic brain injury and ischemic stroke;
during the rehabilitation period of hemorrhagic and ischemic strokes;
degenerative diseases and vascular problems associated with the human brain;
for the treatment of traumatic brain injuries.

The drug has an effective effect on the body in the treatment in neurology of disorders of vascular and degenerative etiology of a motor and sensory nature.

This drug may be part of therapy for:

The emergence of difficulties in performing simple activities related to household services.
Loss of initiative.
Poor memory condition.

Contraindications. Additional contraindications

This drug has a number of contraindications. Ceraxon should not be used in any form:

If you have a high sensitivity to the constituent substances of the drug;
For patients with high tone of the parasympathetic nervous system;
For rare diseases at the genetic level;
Treatment is contraindicated in children under 18 years of age. In critical cases, it is prescribed for children over 6 years of age. However, there have been cases where the drug was used to treat infants born prematurely.

The question regarding the use of this drug during treatment during pregnancy is resolved with the attending physician individually for each case.

A medication is prescribed only when the chance of benefit is higher than the chance of risky consequences. To reduce the likelihood of negative consequences, women taking this drug should stop breastfeeding.

Side effects

In some cases, Ceraxon causes the appearance of:

sleep disturbance;
headaches and periodic migraines;
dizziness;
excitement of the body;
the appearance of hallucinations;
feelings of numbness in the affected limbs;
the occurrence of edema;
decreased appetite, nausea and vomiting;
fever and heat;
itching of the skin and rash on the body;
problems with breathing;
pressure surges.

Based on reviews on the Internet, this drug has virtually no side effects.

Overdose

According to the instructions, in case of an overdose of the medication, one side effect may occur. With large volumes of use, the side effects of the drug on the human body increase.

To eliminate the resulting reaction, symptomatic treatment is carried out.

Price and analogues of Ceraxon

I consider one of the main disadvantages of the drug to be its high price. Ceraxon is produced in Spain, so its cost is pegged to the euro. I bought an injection solution (1000 mg/4 ml) for 1610 rubles. This is 10 ampoules, but still a little expensive. I believe that domestic pharmaceutical companies should also master the production of nootropics.

For those who cannot afford Cerakson, I will give a small list of analogues. To be honest, I haven’t checked their price, but you might be able to save a little. In people's reviews, the most common references were to such products as “Glycine”, “Tanakan”, “Nootropil” and “Cavinton”. The main thing is to discuss your choice with your doctor.

Directions for use and doses

Solution for intravenous and intramuscular administration

IV, IM.

IV, in the form of a slow IV injection (over 3–5 minutes, depending on the prescribed dose) or IV drip infusion (40–60 drops per minute).

The intravenous route of administration is preferable to the intramuscular route. When administered intramuscularly, repeated administration of the drug in the same place should be avoided.

Recommended dosage regimen

Acute period of ischemic stroke and TBI:

1000 mg every 12 hours from the first day after diagnosis, duration of treatment for at least 6 weeks. 3-5 days after the start of treatment (if swallowing function is not impaired), it is possible to switch to oral forms of the drug Ceraxon.

Recovery period of ischemic and hemorrhagic strokes, recovery period of TBI, cognitive and behavioral disorders in degenerative and vascular diseases of the brain:

500–2000 mg per day. The dosage and duration of treatment depend on the severity of the symptoms of the disease. It is possible to use oral forms of the drug Ceraxon.

Elderly patients

When prescribing Ceraxon to elderly patients, no dose adjustment is required.

The solution in the ampoule is intended for single use. It must be used immediately after opening the ampoule.

The drug is compatible with all types of intravenous isotonic solutions and dextrose solutions.

Oral solution

Inside.

Before use, the drug can be diluted in a small amount of water (120 ml or 1/2 cup). Take with meals or between meals.

Recommended dosage regimen

Acute period of ischemic stroke and TBI:

1000 mg (10 ml) every 12 hours. Treatment duration is at least 6 weeks.

Recovery period of ischemic and hemorrhagic strokes, recovery period of TBI, cognitive and behavioral disorders in degenerative and vascular diseases of the brain:

500–2000 mg per day (5–10 ml 1–2 times per day). The dosage and duration of treatment depend on the severity of the symptoms of the disease.

Elderly patients

When prescribing Ceraxon to elderly patients, no dose adjustment is required.

Instructions for using the dosing syringe:

1. Place the dosing syringe into the bottle (the syringe plunger is completely lowered).

Gently pull the plunger of the dosing syringe until the solution level is equal to the corresponding mark on the syringe

3. Before taking, the required amount of solution can be diluted in 1/2 glass of water (120 ml).

After each use, it is recommended to rinse the dosing syringe with water.

Contraindications

Cerakson solution for oral administration:

vagotonia (predominance of the tone of the parasympathetic part of the autonomic nervous system);
children and adolescents under 18 years of age (due to lack of data);
hypersensitivity to the components of the drug.

Cerakson solution d/iv and i/m administration:

hypersensitivity to any of the components of Ceraxon;
patients with vagotonia (predominance of the tone of the parasympathetic component of the autonomic nervous system);
children under 18 years of age (due to lack of data).

Although childhood is considered a direct contraindication, doctors often prescribe this medicine even to children. And if a child is prescribed this kind of medication, it is probably worth knowing the norms of blood pressure and pulse in children.

Cheap analogues of the drug

Not everyone can afford to buy Ceraxon, so below are product analogues, or so-called generics.

A vasodilator that helps improve blood circulation.

treatment of psychoorganic syndrome of any origin;
acute and chronic vascular diseases;
inflammatory and infectious diseases of the central nervous system.

Memotropil

Helps improve metabolic processes in the brain, causes an increase in the concentration of denosine triphosphoric acid, improves memory and simplifies the learning process.

diseases of the central nervous system;
circulatory disorders in the brain;
depression.

Helps improve blood circulation, improve metabolic processes in the brain, and causes an increase in the concentration of denosine triphosphoric acid.

serious cerebral circulatory disorders;
treatment of complications resulting from circulatory disorders in the brain.

Normalizes low levels of metabolic processes in the brain, and also normalizes the structure of neuron membranes and prevents their damage.

cerebral circulatory disorders;
decreased brain performance;
memory impairment;
excessive fatigue.

Andrey 3 months ago

“the analogues given below” have nothing to do with generics. Why be misleading? QUANIL (Kusum), PHARMAKSON (NIKO LLC), DIPHOSPHOCIN (Magis Pharmaceutici), NEURODAR (Amaxa Pharma), NEOCEBRONEuro-Pharma......and not offer fezam from the cerebellum, which contains cave cinnarizine (a failed antipsychotic), which is shoved into everything that is possible, despite a bunch of side effects and no effectiveness.

Any reprinting of materials is possible only with an active link to https://neurodoc.ru/ The opinion of the editors does not always coincide with the opinion of the authors.

Analogues of the drug Cerakson

There are no complete analogues. The group of nootropic drugs includes:

Escotropile.
Ampasse.
Cereton.
Phenotropil.
Pyriditol.
Pantogam active.
Gliatilin.
Glutamic acid.
Tenoten.
Picanoil.
Glycine.
Intellan.
Ginkyo.
Neuromet.
Cebrilyzin.
Stamin.
Pantogam.
Gamma-aminobutyric acid.
Nootropil.
Idebenone.
Aminalon.
Encephabol.
Delecite.
Glycerylphosphorylcholine hydrate.
Cerepro.
Cerebrolysate.
Gleazer.
Pyramem.
Gammalon.
Gopantam.
Piracetam.
Choline alfoscerate.
Calcium hopantenate.
Mexipridol.
Nooclerin.
Noocetam.
Cerebrolysin.
Meclofenoxate hydrochloride.
Noben.
Cortexin for children.
Semax.
Pramistar.
Pyratropil.
Pikogam.
Demanol.
Cortexin.
Minisem.
Cerutile.
Hopantenic acid.
Lutsetam.
Pantocalcin.
Cerebril.
Amylonosar.
Memotropil.
Pirabene.
Picamilon.
Noopept.
Ginos.
Cerebramin.
Mexiprim.
Nootobril.
Energy ball.
Holitylin.
Phenibut.
Mexicofin.
Tenoten for children.

Side effects of Ceraxon

The drug Ceraxon is usually well tolerated by patients. Allergic reactions rarely occur:

Skin rashes;
Quincke's edema;
Skin itching
Anaphylactic shock.

The manipulation rooms of the Yusupov Hospital are equipped with an anti-shock kit. If allergic reactions develop, the drug is stopped, patients are treated with antihistamines, corticosteroids, and in case of shock, blood substitutes and drugs that improve cardiac function are administered.

Patients who take Ceraxon sometimes complain of headache, dizziness, and feeling hot. They may experience trembling of the limbs, nausea, vomiting, and diarrhea. Sometimes hallucinations, shortness of breath, insomnia develop, agitation occurs, appetite decreases, numbness appears in paralyzed limbs, and the activity of liver enzymes changes. In some patients, the drug Ceraxon stimulates the parasympathetic system and causes a short-term change in blood pressure.

Mechanism of action of Ceraxon

Citicoline is a precursor to key ultrastructural components of the cell membrane (mainly phospholipids). Has a wide spectrum of action:

Restores damaged cell membranes;
Inhibits the action of phospholipases;
Prevents excessive formation of free radicals;

Prevents the death of neurons by affecting the mechanisms of apoptosis - programmed cell death. In the acute period of stroke, due to the effects of citicoline, the volume of damage to brain tissue decreases and cholinergic transmission improves. In patients after traumatic brain injury, taking Ceraxon solution orally during the rehabilitation period reduces the severity of neurological symptoms and the duration of restoration of impaired functions of the central nervous system.

In case of chronic cerebral hypoxia, citicoline reduces the severity of cognitive disorders:

Memory impairment;
Lack of initiative;
Difficulties that arise when performing daily activities and self-care.

The drug increases the level of attention and consciousness, reduces the manifestation of memory loss. Doctors at the Yusupov Hospital note the effectiveness of Ceraxon in the treatment of sensory and motor neurological disorders, vascular diseases and degenerative processes of the brain. After taking Ceraxon syrup orally, the active substance is completely absorbed. Its bioavailability is almost the same as after intravenous administration.

How to take Ceraxon in solution

Ceraxon solution is taken orally, following the following algorithm:

Place the dosing syringe into the bottle (the syringe plunger must be completely lowered); Carefully pull the plunger of the dosing syringe until the solution level is equal to the corresponding mark on the syringe; Take the syrup internally, after dissolving it in half a glass of water; After each use, it is recommended to rinse the dosing syringe with water.

In order to take the contents of a packet of Ceraxon solution inside, it is necessary to separate one bag from the other along the tear seam

Holding the bag vertically, carefully tear off its edge along the edge and drink the contents. Before taking, Ceraxon syrup can be diluted in 120 ml of water.

In order to get advice from a neurologist about taking Ceraxon solution orally, make an appointment by phone.

Author

Irina Gennadievna Smolentseva

Head of the Research Center for Parkinson's Disease, neurologist, Doctor of Medical Sciences, Professor

Analogs

The nootropic drug Ceraxon has analogues with an identical composition:

Neupilept Sotex (injection solution, 125 mg, 5 amp.) – 535 rubles; 250 mg – 830 rub.;
Recognan Alpha Wasserman (solution, 10 sachets of 10 ml, 100 mg) – RUB 1,359;
Ceresil Canon Armavir Biological Factory (injections, 250 mg, 5 amps) – 805 rub.

Almost any pharmacy has cheaper analogues in stock.

Among the famous:

Vinpocetine (tablets, ampoules) – from 24 to 190 rubles per pack;
Vinpotropil (capsules) – from 145 rubles;
Cavinton (ampoules) – from 215 rubles.

Only the attending physician should decide what to replace Cerakson with, taking into account the real picture of the disease and the characteristics of the body.

Cytokon (cheaper);
Citicoline from different manufacturers, among which you can choose cheap Russian or foreign analogues;
Farmakson;
Somazina;
Ronocyte (Renocyte);
Novaxon;
Recognan;
Neuroxon;
Neocebron;
Neurodar;
Somaxon;
Kemodin;
Kwanil;
Dendrix;
Diphosphocin;
Axotilin.

Ceraxon can be replaced with any drug from the list above, since their effectiveness has been proven (it cannot be said that certain drugs are more effective).

Our specialists

Andrey Igorevich Volkov

Neurologist, Candidate of Medical Sciences

Daria Dmitrievna Eliseeva

neurologist, candidate of medical sciences

Tatyana Aleksandrovna Kosova

Head of the Department of Rehabilitation Medicine, Physiotherapy Physician, Neurologist, Reflexologist

Elena Gennadievna Petrova

Physiotherapist, Candidate of Medical Sciences

Maxim Vladimirovich Chulkov

Instructor-methodologist in physical therapy, kinesiotherapist

Sergey Olegovich Molchanov

Instructor-methodologist for physical therapy

How to give Ceraxon to children under one year old

Ceraxon is prescribed to newborns for congenital neurological disorders, cerebral palsy, and delayed mental development of the child.

The official instructions do not contain information about taking Ceraxon for children under one year of age. As many years of experience of pediatricians and child neurologists show, the drug is indispensable for many diseases of the central nervous system in children. In small dosages, it is useful for infants and does not have a negative effect on their body.

Since Ceraxon protects nerve cells from negative factors, including reduced oxygen levels, the drug helps to minimize the effects of hypoxia and restore the activity of the nervous system after birth trauma.

How to give Ceraxon to a child under one year old is decided by the attending physician. Often, infants are prescribed syrup or suspension. The dosage and duration of treatment is determined by the pediatrician together with the pediatric neurologist. Syrup should be given to the baby along with food, mixing the medicine with breast milk or an adapted milk formula. The dosage for infants is usually 0.5 ml of the drug 2 times a day. The duration of therapy with Ceraxon for newborns with hypoxia is no more than 12 weeks.

Ceraxon is an effective drug for the treatment of neurological diseases in children. To receive detailed advice on its use, please call. The contact center of the Yusupov Hospital operates around the clock, 7 days a week, without days off or lunch breaks.

Author

Ekaterina Dmitrievna Abramova

Neurologist, director of the chronic pain clinic

Prices for services *

Name of service	Price
Consultation with a rehabilitation specialist (initial)	Price 5,150 rub.
Consultation with a rehabilitation specialist (secondary)	Price 3,600 rub.
Comprehensive rehabilitation program after stroke	Price from 14,839 rub. per day
Comprehensive rehabilitation program after spinal injury	Price from 15,939 rub. per day
Comprehensive rehabilitation program for Alzheimer's disease	Price from 15,389 rub. per day
Comprehensive rehabilitation program for Parkinson's disease	Price from 13,739 rub. per day
Comprehensive rehabilitation program for multiple sclerosis	Price from 14,839 rub. per day
Massotherapy	Price from 2,200 rub.
Session with a speech therapist	Price from 3,410 rub.
Individual lesson on psychological social adaptation	Price 4,565 rub.
Acupuncture session	Price 4,290 rub.

We work around the clock

Reviews from neurologists

I have been using Ceraxon in my practice for a long time. The active component justifies the properties declared by the developers.

I prescribe a nootropic drug to speed up the recovery process after strokes of various types, to stop the death of brain cells during acute attacks. The risk of developing side effects is minimal, which is important in any therapy.

Newborns born prematurely develop more slowly, so help is required in activating physiological processes. Children with developmental disorders and congenital pathologies associated with blood circulation in the brain and blood vessels need the participation of doctors. Cerakson is highly effective in these cases, causing virtually no side effects.

Features of use

Before prescribing a solution for parenteral administration of Ceraxon, the doctor carefully studies the annotation for it, and also pays attention to several features of its correct use:

The simultaneous administration of this drug with drugs that contain meclofenoxate is not recommended.
Ceraxon injection solution may enhance the therapeutic effects of Levodopa.
Clinical data on the effect of the drug on the body of the developing fetus is currently limited, therefore the use of Ceraxon solution for pregnant women is not recommended (it is possible only for health reasons).
While using this drug, engaging in potentially dangerous activities that require sufficient speed of psychomotor reactions and concentration of attention is excluded.

In the pharmacy chain, Ceraxon injection solution is available with a prescription. Its independent use without appropriate medical prescriptions is prohibited, as this can cause negative health consequences.

Pharmacological group

Based on the type of therapeutic action, the drug Ceraxon belongs to the group of nootropic drugs with a wide spectrum of effects. Among the main effects provided by the active component of the product are:

improving the quality of cholinergic synapses in the brain;
inhibition of the activity of phospholipase enzymes;
restoration of damaged cell membranes;
reducing the duration of being in a comatose state and the frequency of various neurological manifestations;
preventing the formation of free radicals;
a significant reduction in the area of damage to brain tissue in a state of acute stroke;
helps speed up the recovery period.

In the case of the development of chronic hypoxia, Ceraxon has a positive effect on various cognitive pathologies. These include:

memory impairment;
apathy and lack of initiative;
difficulty performing daily self-care activities.

During therapy with Ceraxon, not only the ability to remember information improves, but also concentration, performance and the general state of brain activity.

Pharmacokinetics

Citicoline is well absorbed when taken orally. Absorption after oral administration is almost complete, and bioavailability is approximately the same as after intravenous administration. The drug is metabolized in the intestines and in the liver with the formation of choline and cytidine. After administration, the concentration of choline in the blood plasma increases significantly. Citicoline is largely distributed in the structures of the brain, with the rapid introduction of choline fractions into structural phospholipids and cytidine fractions into cytidine nucleotides and nucleic acids. Citicoline penetrates the brain and is actively integrated into cellular, cytoplasmic and mitochondrial membranes, forming part of the fraction of structural phospholipids. Only 15% of the administered dose of citicoline is excreted from the human body: less than 3% - by the kidneys and through the intestines and about 12% - with exhaled CO2 The excretion of citicoline in urine can be divided into 2 phases: a first phase, lasting about 36 hours, during which the rate of excretion decreases rapidly, and a second phase, during which the rate of excretion decreases much more slowly. The same thing is observed in exhaled CO2 - the rate of elimination decreases rapidly after about 15 hours, and then decreases much more slowly.

Recognan

Recognan is a substitute for Ceraxon containing the active ingredient Citicoline. Cheaper than previous drugs: its price ranges from 400 to 600 rubles per 30 ml of syrup for oral administration. The medicine is also available in a solution for administration of 4 ml. Produced by the Moscow Endocrine Plant in Russia and the Alpha Wassermann company in Italy.

A dosage of 1000 mg of Recognan, an analogue of Ceraxon, twice a day is sufficient for positive dynamics in the treatment of conditions that are accompanied by impaired coordination, attention, and disorders of consciousness. Stimulation of cerebral vessels occurs due to an increase in the level of choline in the blood plasma. In the structures of brain cells, active penetration of the substance into the mitochondrial and cytoplasmic membranes occurs.

Overdose and additional instructions

Cases of using a dose of the drug in excess of the norm have not been recorded, since the toxicity of the drug is extremely low.

Side effects

Among the main side effects:

impaired breathing (shortness of breath);
various types of allergic reactions (skin rash, itching, anaphylactic shock);
loss of appetite;
gastrointestinal disorders, etc.;
problems with the cardiovascular system (differences in blood pressure, feeling hot);
problems of the central nervous system (tremor of the limbs, hyperexcitability, hallucinations, etc.).

special instructions

During pregnancy and lactation, treatment with Cerakson is prescribed only when absolutely necessary, when the intended benefit of its use outweighs the possible risk. Although no studies have been conducted on the effect of the drug on the fetus. There are no research results on the possibility of the substance passing into breast milk, but as a rule, it is recommended to stop breastfeeding.

Children

Cerakson is usually not prescribed to patients under 18 years of age due to a lack of clinical studies. Impact on the ability to control vehicles when working with complex mechanisms. Ceraxon does not affect the ability to control vehicles when working with complex mechanisms. In some cases, some side effects associated with disruption of the central nervous system may affect the ability to control vehicles when working with complex mechanisms.

Interactions with other drugs

This product should not be used in parallel with medications that contain parachlorophenoxyacetic acid b-dimethylaminoethyl ester hydrochloride.

Also, Cerakson probably enhances the properties of the substances that make up Levodopa.

During pregnancy, treatment with Ceraxon is prescribed only when absolutely necessary, when the expected benefit of its use outweighs the possible risk. Although no studies have been conducted on the effect of the drug on the fetus

Side effects and interactions with other drugs

When ingesting Ceraxon solution, the following side effects may very rarely occur:

Allergic reactions (rash, itchy skin, anaphylactic shock);
Nausea, vomiting, diarrhea;
Feeling hot, shaking hands;
Headache, dizziness;
Hallucinations;
Decreased appetite;
Edema;
Insomnia;
Dyspnea;
Excitation;
Changes in the activity of liver enzymes.

In some cases, Ceraxon, when taken orally, can stimulate the parasympathetic system and cause a short-term change in blood pressure. If any of the side effects indicated in the instructions for use of the Ceraxon oral solution worsen or doctors at the Yusupov Hospital notice another side effect, they discontinue the drug and carry out symptomatic therapy.

The active substance of the Ceraxon suspension, citicoline, enhances the effects of levodopa. The drug is not prescribed simultaneously with drugs that contain meclofenoxate. When prescribing Ceraxon solution to elderly patients, no dose adjustment is required.

Ceraxon injections

The drug has the form of a liquid that is colorless, odorless and tasteless.

It is usually administered intravenously at a slow pace or through a dropper. Each ampoule has a volume of 4 ml. contains 522.5 mg or 1045 mg of citicoline sodium.

In addition, the solution contains a solution of sodium hydroxide or hydrochloric acid. After opening the drug, the ampoule itself and the remaining medication must be thrown away.

In pharmacology, the following methods of release are distinguished:

solution - 500 mg, ampoules of 4 ml No. 3;
solution for injection 500 mg, in ampoules of 4 ml No. 5;
solution for injections 500 mg, with ampoules of 4 ml No. 10;
solution – 1000 mg, in ampoules of 4 ml No. 3;
solution for injections 1000 mg, in ampoules of 4 ml No. 5;
solution – 1000 mg, in ampoules of 4 ml No. 10;

Based on the characteristics of the disease, Ceraxon is administered 1 g twice a day or 5-10 mg once to twice a day.

Release form and active components in the composition

In the pharmacy chain, the nootropic "Ceraxon", the instructions for use confirms this, is presented in various forms:

for oral administration - liquid solution;
for injection solution - in transparent glass ampoules;
oblong, coated tablets.

The active component of the drug is Citicoline. It has nootropic effects.

The solution for injection delivery of the drug may contain 500 or 1000 mg of the active component. Among the auxiliary components, the instructions indicate: sodium hydroxide and hydrochloric acid, as well as water for injection. In a consumer box, the product in a volume of 4 ml is packaged in cellular packaging, 5 pcs. in each.

The solution for oral administration is presented in bottles of 30 ml, with the active substance 10 g. The consumer pack contains 1 bottle.

If you purchase a tablet form of the medicine, then each tablet contains 500 mg of Citicoline, as well as excipients that enhance the pharmacological properties of the main component. In the pharmacy pack they are presented in protective blisters of 20 pcs.: 5 pcs. in one blister.

Side effects

In general, Ceraxon injection solution is well tolerated. Very rarely (1 case per 1000 administrations of the drug), allergic reactions may develop (skin rash, itching, urticaria, angioedema), insomnia, nausea, vomiting, dizziness, diarrhea, headache, tremor (shaking hands), hallucinations, peripheral edema, shortness of breath, loss of appetite. Due to the effect of the drug on the parasympathetic part of the nervous system, a short-term change in the level of systemic blood pressure is possible. If signs of negative side reactions develop, the possibility of further use of the drug is determined only by the attending physician, which depends on their nature and severity.

Side effects after taking the drug

From the central and peripheral nervous system: severe headache, vertigo, hallucinations.
From the cardiovascular system: hypertension, arterial hypotension, tachycardia.
From the respiratory system: shortness of breath.
From the digestive tract: nausea, vomiting, diarrhea.
From the immune system: allergic reactions, including rash, hyperemia, exanthema, urticaria, purpura, itching, angioedema, anaphylactic shock.
General reactions: chills, changes at the injection site.

Ceraxon tablets

The medicine package contains 20 white, oblong tablets. Each contains about 500 mg of the active ingredient citicoline.

You can read the instructions for use of the drug Citicoline here.

This item:

promotes the emergence of new phospholipids, as a result of which improves the functioning of nerve cell membranes;

reduces the degree of cerebral edema;

improves memory and attention;

favors the recovery process after a stroke;

preserves the energy supply of neurons;

restores functional recovery in case of cerebral circulatory disorders.

In addition, the tablet contains:

talc;
magnesium stearate;
anhydrous silica;
croscarmellose sodium;
Castor oil.

The period of use, adjusted by the attending physician, averages from 1 to 2 months. Based on the different levels of severity of the disease, the dose of medication per day ranges from 1-4 tablets.

Ceraxon tablets are used if the patient has the ability to swallow independently. The drug is also prescribed both for universal treatment with other medications, and independently.

https://youtube.com/watch?v=-30MplMXa_M

Analogs and price

Cerebrolysin is intended for patients who have disorders in the central nervous system, various mental illnesses, memory impairment, absent-mindedness, and cerebrovascular disorders. The active substance has a similar name - Cerebrolysin. Available in ampoules for injection.
Somaxon - like Ceraxon, restores damaged cell membranes and also reduces the volume of brain damage after a stroke. The active ingredient is citicoline.
Somazina - reduces cerebral swelling and also promotes rapid recovery after a stroke. The active ingredient is citicoline. This analogue is available in tablets, oral solution and injection solution.

The price of Cerakson in different pharmacies may vary significantly. This is due to the use of cheaper components and the pricing policy of the pharmacy chain.

The average price for Ceraxon amp. 500 mg, 5 pcs. – 735 rubles.

The effect of the drug in relation to children

"Ceraxon" - a solution for oral administration - receives mostly positive reviews from parents. So, doctors often prescribe this drug to babies who at birth had problems such as hypoxia, enlargement of parts of the brain, and abnormal brain function. After the children were treated with this medication, the result pleasantly surprised the parents. After treatment with Ceraxon, the children’s motor skills improved (for example, rolling over, standing up, sitting), and muscle tone returned to normal. Older children who were treated with this medication experienced improved memory and concentration, boys and girls became more diligent and attentive.

And the drug “Cerakson” helped many parents, whose children until a certain age (for example, at 4-5 years old) could not yet speak, to develop the speech of their offspring. After treatment with this remedy, mothers could not recognize their children: boys and girls began to babble so that it was difficult to stop them. In general, this drug is truly effective, and this is proven by numerous reviews from people on various forums.

In addition to the undoubted positive result, parents like the convenient form of release of the medicine.

The pleasant strawberry taste of the medicine is another advantage, because which child would want to drink a tasteless medicine? But here the manufacturer was concerned about the kids and invented a special form of the drug in the form of a sweet solution for children.

Patient reviews

Many medications have been prescribed following ischemic stroke. When the doctor left Cerakson for a long-term appointment, the hope for a complete restoration of speech seemed illusory.

But my fears were in vain, the drug helped me return to normal life, mooing and loss of letters in words became barely noticeable. After 4 months I spoke as before the illness, but maybe not so quickly.

My son at 4 years old spoke barely understandable phrases. The pediatrician, together with the neurologist, prescribed Cerakson.

Six months later, the child made great progress in mastering speech, the words became clear and completely understandable. Positive dynamics were also noted in educational games, the assimilation reaction accelerated, and the son made decisions instantly.

During a difficult birth, the child got stuck in the passageways, which caused hypoxia. The doctors made every effort to save my daughter.

Any drugs with which she was treated alarmed me. I read the annotations to them and got acquainted with the list of side effects.

Concerns about Ceraxon turned out to be unfounded. The injections helped stop the death of brain cells and restore normal blood circulation. The injections did not cause any negative effects.

Storage conditions

Store at a temperature not exceeding 30 °C. Keep out of the reach of children.

Storage of the Ceraxon form taken orally is recommended at a temperature not exceeding 30 degrees. If such strawberry medicine is placed in a cold place, crystals may appear in the solution, which will dissolve on their own after several months of storage at room temperature and do not in any way affect the quality of the medicine. The shelf life of the drug is 3 years.

The solution in ampoules is also valid for 3 years from the date of manufacture. It, like the drug for oral administration, can be stored at temperatures below 30 degrees Celsius. The medicine from the opened ampoule is used for one injection.

Compatibility of Ceraxon with other drugs

Sometimes patients take Ceraxon and Mexidol together. Both drugs have a nootropic effect, despite the fact that they contain different active substances. They are completely compatible. The appropriateness of using drugs from one pharmacological group is determined by the attending physician.

Ceraxon and Omacor are used in complex therapy of diseases of the central nervous system. The main active ingredient is citicoline sodium. The drug has the following effects:

Restores nerve cell membranes;
Prevents the formation of free radicals;
Prevents the death of nerve cells.

Omacor is a lipid-lowering drug consisting of omega-3-ethyl esters of acids. The drug affects blood plasma lipids and reduces triglyceride levels. As a result of this action, the level of very low density lipids in the blood decreases. Ceraxon and Omacor can be taken simultaneously.

Patients are often interested in the compatibility of Ceraxon and Cavinton. The active ingredient of the drug Ceraxon is citicoline. It is by its nature a natural compound (produced in a certain amount in the human body). The main contraindication to taking Ceraxon is hypersensitivity to the components of the drug. It has little interaction with other drugs. Used for cerebrovascular disorders.

Cavinton is a herbal preparation. Contains Vinca minor extract. Positively affects metabolic processes and blood supply to the brain. Taking into account this action, Ceraxon and Cavinton complement each other. During complex therapy with Ceraxon and Cavinton, no dose adjustment is required.

The compatibility of Ceraxon with Atarax is beyond doubt. According to the information contained in the instructions for use of both drugs, they do not interact with each other. Neurologists at the Yusupov Hospital individually determine which drugs to prescribe together with Ceraxon.

How to use Ceraxon syrup correctly? Instructions for use for children.

The dosage of Ceraxon depends on the severity of damage to the nervous system, on the age of the child, on his body weight, on the reaction of the child’s body to taking the drug, on the degree of prematurity of the baby. Therefore, you should definitely consult with your pediatrician before you start giving your child Cerakson. The instructions for children are as follows :

for very premature babies whose body weight is very low - 0.5 milliliters of syrup twice a day;
children over two months old - 1 milliliter of syrup twice a day.

Subsequently, the daily dosage of Ceraxon should not be more than 5 – 20 milliliters. The optimal duration of the course of taking syrup is 12 weeks.

Ceraxon is highly effective for children. Reviews about this syrup are only positive . If you prescribe the drug promptly in the early stages of the disease, the results will be amazing: the child’s auditory, speech, static, motor and emotional functions improve.

In pediatric practice, modern doctors very often encounter neurological and mental disorders in children. The high prevalence of diseases of the central nervous system (CNS) is associated with the negative impact of the environment, poor ecology, bad habits of parents, untimely referral of a pregnant woman to an antenatal clinic, as well as with problems that arose directly during childbirth. Fortunately, pediatricians, together with pediatric neurologists, are actively studying the pathology of the central nervous system in children and are looking for new ways to treat these diseases. Today, one of the best drugs that affects the nervous and mental system of a child is Ceraxon. This drug is prescribed to children for many diseases. What is Ceraxon, what is this drug for and how to take it correctly?

Reviews

In most cases, people respond positively to Cerakson, noting the pronounced therapeutic effect of such a drug. According to parents, the medication helps eliminate the effects of damage to brain cells, and has also proven itself as a means of stimulating speech development. Its advantages also include its liquid form and good tolerability. Such a medicine rarely causes negative side effects, and among its disadvantages, only high cost is usually mentioned.

How to use "Cerakson": instructions

Reviews from doctors are abundant in specialized publications and indicate the high effectiveness of the drug. It is prescribed as part of complex treatment or separately during therapy:

traumatic brain injuries (during recovery and acute periods);
ischemic stroke in the acute period;
hemorrhagic and ischemic strokes (during the recovery period);
behavioral and cognitive disorders that are caused by vascular and degenerative diseases of the brain.

Composition and form of release, principle of action

The instructions for use for Ceraxon indicate that the product is available in two versions: syrup for oral use and ampoules for injection (both intramuscular and intravenous). In some cases, it makes sense to combine both of these forms, sometimes to first conduct a course of injections, then use syrup as maintenance therapy.

The main active ingredient of the drug is citicoline. This substance helps improve the function of ion exchange pumps in the membranes of nervous system cells. As a result of regular use, the strength of the walls of the membrane of neurons (nerve cells) increases and strengthens, thanks to which it is possible to reduce cerebral edema, increase cognitive abilities, reduce psycho-emotional stress and manifestations of various types of psychoses. The composition of Cerakson syrup also includes auxiliary components. These are sorbitol, glycerin, strawberry essence, saccharin, dyes and citric acid.

In people with traumatic brain injury, treatment with this drug can reduce the duration of post-traumatic coma and the intensity of neurological symptoms. Under the influence of citicoline, the duration of the recovery period after a stroke decreases.

In persons with chronic cerebral hypoxia (which can develop under the influence of certain conditions, organic lesions, injuries, or even chronic alcoholism), while taking Cerakson syrup, there is an improvement in memory, cognitive processes, increased attentiveness and observation, and symptoms of attention deficit disappear. and hyperactivity (if you have such a diagnosis, it makes sense to create a complex therapy and also include nootropics). Self-administration of the drug is prohibited; it can be purchased at a pharmacy only with a prescription from a doctor.

When is the medication prescribed?

According to the instructions for use, it is known that the drug “Citicoline” is recommended for use in the presence of certain pathological conditions. Indications for use of the drug "Citicoline":

Acute stage of ischemic stroke (impaired microcirculation of blood in the brain with disruption of tissue, as well as its functions).
Cerebral infarction (a serious disease characterized by death of brain tissue).
Hemorrhagic stroke (impaired microcirculation of blood in the brain with breakthrough of blood vessels, as well as hemorrhage in the brain).
Cognitive and behavioral disorders.
Traumatic brain injury.
Amyotrophic lateral sclerosis (a disease that is accompanied by the death of central or peripheral motor neurons).
Chorea (a pathological condition characterized by involuntary and chaotic movements of the legs and arms).
Alzheimer's disease (complex lesions of the nervous system, characterized by loss of memory and logical thinking, as well as speech inhibition).
Parkinsonism (a neurological disease characterized by a number of symptoms: tremor, resistant increase in muscle tone, uniform muscle resistance, equally expressed in flexion and extension, as well as postural instability and slow movement).
Discirculatory encephalopathy (a disease of the brain that occurs as a result of a chronic progressive disorder of the microcirculation of the brain of various origins).

Description of the drug

Ceraxon is a modern drug from the group of synthetic nootropics. Often prescribed by doctors to solve the problems described above. The main substance included in its composition, Citicoline sodium, is the basis for cell membranes of phospholipids (specific cells of nervous tissue). It has a very broad spectrum of action, due to which it is actively used in pharmacology.

The main area of application is the treatment and correction of brain pathologies, such as stroke, traumatic brain injury, chronic oxygen deprivation of the brain, problems with memory, concentration and others. It is also actively used for neurological disorders of vascular origin.

The action of Ceraxon, like other nootropics, is based on enhancing ATP synthesis, accelerating and enhancing the effects of providing the brain with oxygen. Nootropic drugs help connect nerve cells with each other. Penetrating into the brain, Citicoline is embedded in the membranes, eliminating voids formed as a result of injuries, age-related changes and other reasons.

Thus, the drug restores the integrity and viability of brain cells. In a word, these are substances that help restore and maintain the viability of nerve cells that lose their activity. Consequently, they are indispensable for any disorders of human brain activity, increased stress on the brain, adverse environmental factors and some other problems.

Citicoline solves different problems in different ways. In case of stroke (rupture or blockage of a vessel supplying the brain), Citicoline significantly reduces the area of brain damage, reducing the volume of affected tissue. In case of TBI, it shortens the time of coma and, accordingly, promotes the rapid “inclusion” of brain cells in work. This reduces the time of the rehabilitation stage.

Helps with weakening memory and decreased attention. Used to slow down daily activities and helps saturate the brain with oxygen. The product nourishes the brain and enhances human cognitive abilities.

In a word, the pharmacological properties of the drug are extensive. A drug:

It restores damaged cell membranes well.
Establishes and regulates cholinergic transmission in neurons.
Maximizes the volume of damaged brain cells after a stroke.
Reduces the rate of chemical reactions.
To the maximum, it prevents the release of free radicals in tissues.
Prevents the formation of fatty acids.

Release form

Solution for oral administration and injection. The specific form is prescribed based on medical indicators, the degree and phase of neglect of the pathology, the patient’s condition, and concomitant diseases. The difference lies in the concentration of the active substance and the speed at which the healing process begins. With intravenous administration, the rate of delivery of the medicinal substance is higher than when taking the solution orally. When administered intravenously, the drug instantly spreads throughout the body through the bloodstream. It is sold based on a doctor's prescription.

Additionally

In the cold, a small amount of crystals may form due to temporary partial crystallization of the preservative. With further storage under recommended conditions, the crystals dissolve within several months. The presence of crystals does not affect the quality of the drug.

During the treatment period, care should be taken when performing potentially hazardous activities that require special attention and quick reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher and operator, etc.).

Compatibility of Ceraxon and alcohol

The simultaneous use of medication and ethanol is prohibited. A number of negative consequences are possible. Cases of hallucinations have been recorded. The pressure can change dramatically in any direction.

Concurrent use is a common cause of acute heart failure. Therefore, doctors always warn that it is important to forget about alcoholic beverages during therapy.

Compliance with the recommendations will ensure comfortable treatment, which is not accompanied by severe disturbances in the functioning of internal organs.

Ceraxon during pregnancy and breastfeeding

There are no sufficient data on the use of citicoline in pregnant women. Although animal studies have not revealed any negative effects, during pregnancy the drug Ceraxon® is prescribed only in cases where the expected benefit to the mother outweighs the potential risk to the fetus.

When prescribing Ceraxon® during lactation, women should stop breastfeeding, since there is no data on the excretion of citicoline in human milk.

The drug is administered intravenously as a slow injection (over 3-5 minutes, depending on the prescribed dose) or drip infusion (40-60 drops per minute). The intravenous route of administration is preferable to the intramuscular route. When administered intramuscularly, repeated administration of the drug in the same place should be avoided.

Acute period of ischemic stroke and traumatic brain injury: the recommended dose is 1000 mg every 12 hours from the first day after diagnosis; the duration of treatment is at least 6 weeks. 3-5 days after the start of treatment (if swallowing function is not impaired), it is possible to switch to oral forms of the drug Ceraxon ®.

Recovery period for ischemic and hemorrhagic strokes, recovery period for traumatic brain injury, cognitive and behavioral disorders in degenerative and vascular diseases of the brain: the recommended dose is 500-2000 mg/day. (5-10 ml 1-2 times/day). The dose and duration of treatment depend on the severity of the symptoms of the disease.

The drug is taken with meals or between meals. Before use, the drug can be diluted in a small amount of water (120 ml or 1/2 cup).

Acute period of ischemic stroke and traumatic brain injury: the recommended dose is 1000 mg (10 ml) every 12 hours. Duration of treatment is at least 6 weeks.

Recovery period of ischemic and hemorrhagic strokes, recovery period of traumatic brain injury, cognitive and behavioral disorders in degenerative and vascular diseases of the brain: the recommended dose is 500-2000 mg/day. (5-10 ml 1-2 times/day). The dose and duration of treatment depend on the severity of the symptoms of the disease.

Very rare (less than 1/10000) (including individual cases): allergic reactions (rash, itching, anaphylactic shock), headache, dizziness, feeling of heat, tremor, nausea, vomiting, diarrhea, hallucinations, swelling, shortness of breath, insomnia, agitation, loss of appetite, numbness in paralyzed limbs, changes in the activity of liver enzymes. In some cases, Ceraxon® can stimulate the parasympathetic system and also cause a short-term change in blood pressure.

If any of the side effects indicated in the instructions get worse, or any other side effects not listed in the instructions are noticed, you should inform your doctor.

Oral solution (optional). In the cold, a small amount of crystals may form due to temporary partial crystallization of the preservative. With further storage under recommended conditions, the crystals dissolve within several months. The presence of crystals does not affect the quality of the drug.

Citicoline enhances the effects of levodopa.

Ceraxon should not be prescribed simultaneously with medications containing meclofenoxate.

Given the low toxicity of the drug, cases of overdose have not been described.

At a temperature not exceeding 30C°.

3 years

Among foreign and Russian analogues of Cerakson there are:

No information.

We automatically found these reviews about the drug Ceraxon on the Internet:

An excellent pharmacy, everything is prompt and professional, even rare drugs are available, reasonable prices. Qualified consultants and responsible couriers, even urgent delivery is “on point”! Good luck! I recommend to everyone

You can leave your review below! Does Ceraxon help cope with the disease?

In the pharmacy chain, the nootropic "Ceraxon", the instructions for use confirms this, is presented in various forms:

for oral administration - liquid solution;
for injection solution - in transparent glass ampoules;
oblong, coated tablets.

The active component of the drug is Citicoline. It has nootropic effects.

The solution for oral administration is presented in bottles of 30 ml, with the active substance 10 g. The consumer pack contains 1 bottle.

Since the drug "Ceraxon", which helps with pathologies of brain activity, is a representative of a subgroup of nootropics, it is characterized by their pharmacological effects on the human body:

actively restores cell membranes that are already damaged;
optimally corrects cholinergic transmission in neurocytes;
significantly reduces the negative manifestations of neurological manifestations;
reduces the duration of coma of post-traumatic origin;
prevents the release of negative radicals in tissues as much as possible;
capable of inhibiting the effects of phospholipases;
best reduces the amount of brain injury caused by strokes.

The remedy has also found its use in the treatment of motor and sensory disorders in neurological practice - of various origins. According to the instructions, the medication “Cerakson” 1000 mg, the instructions for use indicate this, is very effective in correcting the following neurological conditions:

existing difficulty in performing self-care procedures;
lowering memory parameters.

The pharmacological agent significantly reduces the symptoms of amnesia.

Experts recommend the drug in the following cases:

acute period of cerebral catastrophe - stroke;
recovery period after already suffering brain damage;
acute or already recovery period after TBI;
various pathologies of brain structures of a vascular nature of development, in combination with various behavioral disorders and cognitive abilities in the patient.

Only a neurologist should recommend a nootropic drug - after assessing the individual severity of neurological symptoms, the patient’s age category, and his susceptibility to the treatment procedures being performed.

Based on the instructions for the drug "Ceraxon", it follows that the pharmacological drug has the following contraindications for use:

a significant predominance of the tone of the parasympathetic department of the autonomic system;
individual hyperreaction to the active and auxiliary components of the drug "Ceraxon", from which the medicine can cause side effects;
children's category of patients, as well as adolescents under 17–18 years of age.

The drug is used with extreme caution if a person has a disorder of the liver and kidney structures. Under the mandatory supervision of a specialist, with monitoring of biochemical blood parameters.

As a rule, the pharmacological drug "Ceraxon", instructions for use and reviews indicate this, is well tolerated by patients. In rare cases, the following negative effects may occur:

impaired sleep quality;
intense pain impulses in the head;
increased tremor of the limbs;
hyperarousal;
persistent dizziness;
the appearance of various hallucinations;
a pronounced feeling of numbness in paralyzed limbs;
Dyspeptic disorders are possible - nausea, vomiting, or diarrhea:
dermal rashes of an allergic nature, for example, urticaria;
less often - anaphylactic shock.

After discontinuation of the drug, all of the above undesirable effects are completely eliminated.

How to give injections

The solution for injection drug delivery should be administered slowly, in direct proportion to the administered dose of the drug - but not less than 3-5 minutes. If the product is recommended for drip administration, then no more than 40–60 drops per minute. As a rule, the medicine is prescribed to patients mainly intravenously. In severe conditions, for example, a suddenly developed hemorrhagic stroke, the medicine should be administered at the earliest possible stage - to reduce the area of the pathological focus. From the instructions for the medication it follows that its use directly depends on the pathology that was diagnosed in the person:

Acute period of TBI, as well as ischemic stroke - 1000 mg of the drug "Ceraxon" every 10-12 hours, with a treatment course of at least 5.5-6 weeks. Then, based on individual needs, it is possible to switch to taking oral syrup or Ceraxon tablets.

The frequency of administration and the duration of the treatment course are also determined only by the doctor observing the patient. Changing them on your own is unacceptable.

In pediatric practice, the drug is administered strictly under the supervision of a neurologist and according to the dosage specified in the recommendations. In elderly people, it may be necessary to adjust the therapeutic dose.

For oral administration, the medicine is diluted in 100 ml of water. Be sure to drink after eating the main course. In acute cases of TBI or stroke - 1000 mg every 10-12 hours, which is equivalent to 10 ml of syrup or 1 sachet of powder form for preparing a solution. The duration of treatment is at least 5.5–6 weeks.

In pediatrics, the nootropic drug has also found its use for various disorders of the nervous system structures. As a rule, the oral form is taken in an individually selected dose by a specialist.

For premature infants - 50 mg twice a day, for babies from two months - 100 mg in the morning and evening. Then the child’s dose is adjusted, but should not exceed 20 ml of medication per day.

The group of nootropic drugs includes the following analogues, the composition of which varies:

"Choline alfoscerate".
"Encephabol."
"Escotropile."
"Cerebramin."
"Cebrilyzin".
"Memotropil."
"Pyramem."
"Pyriditol."
"Demanol".
"Pantogam asset".
"Semax".
"Cortexin for children."
"Cortexin".
"Pantogam".
"Phenibut."
"Gamma-aminobutyric acid."
"Idebenone."
"Picanoil."
"Piracetam."
"Ginos".
"Meclofenoxate hydrochloride."
"Mexifin."
Neuromet.
"Tenoten."
"Cerebrill."
"Intellan".
"Hopantenic acid".
"Mexipridol."
"Cereton".
"Pyratropil."
"Nootropil"
"Glutamic acid."
"Glycerylphosphorylcholine hydrate."
"Amilonosar."
"Deletite."
"Pramistar."
"Aminalon".
"Mexiprim."
"Nooklerin."
"Picamilon".
"Pikogam."
“Nootobril.”
"Stamin."
"Cerebrolysin".
"Gleazer."
"Pantocalcin".
"Noocetam."
"Calcium hopantenate."
"Cerebrolysate".
"Gopantam."
"Gliatilin".
"Pirabene".
"Tenoten for children."
"Ampasse".
"Noben."
"Enerball".
"Lucetam."
"Phenotropil".
"Minisem."
"Glycine".
"Ginkyo."
"Cerutil".
"Gammalon".
"Holitilin."
"Cerepro."
"Noopept."

You can buy the medicine “Cerakson” in Moscow and regions of Russia for 700 rubles, in Minsk – for 36-92 rubles. ruble In Kazakhstan, tablets cost 9,860 tenge. The price of Ceraxon 1000 mg injections is 453 hryvnia for 5 ampoules.

Numerous positive reviews about the drug “Cerakson” posted on various forums on the Internet indicate that the drug is effective both in the acute period of pathology and in the rehabilitation period. However, in pediatric practice there is little adherence to a nootropic drug. Side effects are possible, for example, hyperreactivity of the child. The drug must be taken under the supervision of a physician.

Ceraxon is a very effective nootropic drug that helps to significantly improve cerebral circulation.

This medication is most often prescribed for the complex treatment of various neurological disorders that are accompanied by decreased memory, coordination of movements, etc.

The main active medicinal substance of Ceraxon is citicline, which helps prevent possible death of cell membranes in the brain, and also helps to significantly improve cerebral circulation.

With long-term use, the drug is well tolerated by many patients without the development of significant secondary complications.

Main indications for use of Ceraxon:

ischemic or hemorrhagic form of stroke;
ACVA (acute cerebrovascular accident);
traumatic brain injuries;
complex treatment of cerebral edema;
memory or attention impairment;
cerebrovascular diseases;
various neurological diseases of the body;
cognitive disorders.

Attention: before starting to use Ceraxon, it is recommended to consult with a qualified general practitioner!

The drug is produced in the form of soluble tablets for internal use, as well as a solution for injection.

The daily dose of this drug is 1 t. 2-4 r. a day after meals, with plenty of water. The maximum daily dose for adults should not exceed more than 2 g.

For fairly severe diseases (stroke, acute cerebrovascular accident), Ceraxon is prescribed in 5-10 ml doses. IV for 7-14 days.

The course of treatment and dose of the drug is determined by the attending physician absolutely individually for each patient, depending on the severity of the specific disease of the body.

Summarizing

The drug Ceraxon has an effective effect on the body. It quickly restores a person’s general well-being after a stroke, is able to reduce the negative consequences of the disease and effectively improves the lost properties of the body.

This drug should not be taken as a means of self-medication. Since the elements of the medication can have a strong effect on the patient, which leads to adverse reactions, constant monitoring by the attending physician is extremely necessary.

Despite the fairly high price, patients have the opportunity to use high-quality analogues, which in most cases are able to provide a similar effect, like Ceraxon.
09/18/2016

Does Cerakson help with RRR in children?

For children, the drug is indicated for:

perinatal encephalopathy (traumatic, toxic effects in utero, during childbirth, in the first year of life);
delayed psychophysical development;
emotional disorders;
speech development delay (SDD).

In case of delayed speech development caused by psychogenic disorders - separation from mother, placement of the child in a boarding school, 24-hour kindergarten, long-term illness - the help of a psychologist is necessary.

If RRR is caused by encephalopathy, vascular disorders of the brain, the effectiveness of the drug is undeniable. It activates speech centers in the cerebral cortex and improves auditory perception. The medication has a beneficial effect on the development of cognitive functions (memory, attention, thinking), which indirectly contribute to the development of speech.

Mechanism of action of Cerakson in ZRR

In case of RRD of organic origin (caused by brain damage due to toxic and/or traumatic effects on the fetus during pregnancy, childbirth or on the brain of the newborn), the nootropic effect of the drug is expressed in:

restoration of damaged neurocytes;
improving the transmission of impulses in brain tissue;
preventing the formation of free radicals, leading to additional intoxication of the brain, the development of vascular and degenerative pathologies;
suppression of the action of phospholipase enzymes involved in the process of cell damage.

Is Cerakson allowed for children under one year of age?

Research in recent years has shown that the medicine can be safely prescribed to babies up to one year old. For children, there is now a special release form of Ceraxon - in the form of a strawberry-flavored syrup. For infants, the medicine is indicated for:

intrauterine hypoxia;
hypoxia during childbirth, caused by obstruction of the birth canal and delayed first breath;
premature

The results of using the medication in children under one year of age revealed a significant improvement in the psycho-emotional state and normalization of psychophysical development.

Ceraxon: instructions for use for children

Doses of the drug depend on the severity of the damage to the central nervous system, the stage of delayed speech development, age, body weight, degree of prematurity of the child, characteristics of the nervous system, and individual response to the drug. Only the doctor selects the dosage for each small patient! Approximate treatment regimen:

Up to
a year .
It is preferable to administer in the form of syrup, but in some cases intramuscular injections are also used. The required dose of syrup is measured with a special syringe located in the package and mixed with a small amount of breast milk or artificial formula. Give 30 minutes to 1 hour after feeding. The course of treatment is 3 months. If necessary, after 3-6 months. the course is repeated. The duration of the course is determined only by the attending physician! Dosages by month for babies under one year of age are presented in Table 1.

Table 1. Dosages of Ceraxon for babies under one year old

Release form
Age (months)	Syrup	Injections
2-4	1 ml 2 times a day	100 mg 2 times a day
5-6	1.5-2 ml 2 times a day	150-200 mg 2 times a day
7	2 ml 2 times a day	200 mg 2 times a day
8-9	2-3 ml 2 times a day	200-300 mg 2 times a day
10-12	3 ml 2 times a day	300 mg 2 times a day

After
a year,
the drug is used in the form of syrup, tablets, suspension, injections. The form of use, dose, frequency and duration of treatment is determined only by a doctor! Table 2 shows approximate doses of the medication for children 1 year old – 14 years old.

Table 2. Doses of Ceraxon for children of different ages

Release form
Age (years)	Suspension	Syrup	Pills	Injections
1-2	1-2 ml 2 times a day	1-2 ml 2 times a day	–	–
3	2 ml 2 times a day	2 ml 2 times a day	1/4 tablet 1-2 times a day	200 mg 2 times a day
4	2-3 ml 2 times a day	2-3 ml 2 times a day	1/4 tablet 1 time per day	200-300 mg 2 times a day
5	3 ml 2 times a day	3 ml 2 times a day	1/2 tablet 1-2 times a day	300 mg 2 times a day
6-10	4 ml 2 times a day	4 ml 2 times a day	1/2 tablet 2 times a day	400 mg 2 times a day
11-14	5 ml 2 times a day	5 ml 2 times a day	1 tablet 1 time per day	500 mg 2 times a day

Side effects in children

As practice shows, adverse reactions in children occur extremely rarely. There may be individual intolerance to syrup components (for example, fructose). In this case, it is necessary to change the form of the drug - give injections or give suspensions. After three years, you can use the tablet form.

Cerakson is not prescribed to children with a predominance of the parasympathetic type of the central nervous system: it can provoke nausea, vomiting, diarrhea, headache, shortness of breath, redness of the skin, tremor, and swelling. Sometimes hallucinations are possible.

All symptoms are quickly relieved by symptomatic therapy. But you can’t do anything on your own! If such phenomena occur, you should immediately consult a doctor!

The drug is not recommended to be prescribed simultaneously with other nootropics, in particular with Meclofenoxate. Ceraxon also enhances the effect of the antiparkinsonian drug Levodopa.

Reviews from parents about Tserakson

Numerous reviews from parents prove the high effectiveness of the use of Ceraxon for cervical cancer.

Anna: We live in a small town, we don’t have the opportunity to visit a psychologist or speech therapist. The doctor prescribed Ceraxon. Drank for 6 months. Before treatment, the child was silent and did not utter a single sound. Six months later he speaks entire sentences!

Vadim: We took the drug for 1.5 months. The child began to answer questions, so far only “yes” and “no”, we hope for further progress. Does not cause allergies, is well tolerated.

Lena: We’ve been taking the medicine for 5 months. In addition to the fact that the child started talking, he became interested in what was happening, he began to dress himself, eat, and tries to draw something. My daughter drinks with pleasure. The drug has a pleasant taste.

Marina: My son is 4 months old. Born with hypoxia. We take Ceraxon for a month. Before him, my son cried all the time, was very restless, and did not latch on to the breast. Now he is smiling, calm, sleeps well, and walks.

Among the disadvantages of the drug, parents note only the high price and rare adverse reactions.

Thus, Cerakson can be safely prescribed to children of any age with gastrointestinal development of organic origin. Important !

It should be remembered that the treatment must be completely carried out by a specialist! Independently selecting, changing the dose, method of administration, setting the regimen and duration of the course of treatment is strictly prohibited!

Alina Veyts, psychoneurologist, candidate of psychological sciences, especially for Mirmam.pro

Operating principle

In its structure, citicoline, which is part of Ceraxon, belongs to the precursors of phospholipids - important components of nerve cell membranes. Thanks to this structure, it is able to restore membranes when they are damaged. In addition, citicoline has the ability to inhibit phospholipases and interfere with the formation of free radicals in large quantities, due to which this substance prevents cell death.

When using Ceraxon, an improvement in the transmission of nerve impulses and a decrease in neurological symptoms caused by cerebral hypoxia are noted. According to neurologists, the drug showed good results in cases of brain damage (reduced the volume of affected tissue) and post-traumatic coma (shortened its duration and contributed to faster recovery). It also helps with memory impairment, problems with speech, attention and other mental processes.

Dosage for children

Ceraxon solution may also be indicated for children.
Boys and girls can be prescribed this drug for lesions of the central nervous system of varying severity. This medicine is highly effective and its side effects are kept to a minimum. “Ceraxon” is an oral solution, instructions for which must be included in the package, and can even be prescribed to infants. This medication perfectly fights damage to the nervous system, it eliminates delays in psycho-speech development, and helps get rid of epileptic symptoms. Thanks to treatment with Ceraxon, the child begins to develop normally emotionally. In addition, the medicine has an excellent effect on the baby’s speech activity and auditory perception, it improves fine motor skills in boys and girls. "Ceraxon" - a solution, instructions for use of which (for children) will be described below, should be prescribed by a doctor individually, depending on the severity of the lesion, as well as the age of the child. The dosage for oral administration is as follows:

— For premature babies – 50 mg 2 times a day.

- Children from 2 months - 100 mg twice a day.

In general, the treatment regimen with Ceraxon should be selected individually. However, mom and dad should know that the baby should not be given more than 20 ml of medicine per day.

Ceraxon for children: how to take it correctly?

Children's Cerakson can be used both in the form of injections and in the form of syrup orally. Cerakson solution for oral administration is best given to newborns and infants, and injection solution and tablets are best given to children aged 2-3 years.

If a child is prescribed this drug in the form of syrup, the mother immediately has a question: Should Ceraxon be given to children before or after meals? As indicated in the instructions, it is best to take the medicine 30 minutes - 1 hour after feeding. This will reduce the risk of nausea and vomiting. The tablets should also be taken after meals. But Ceraxon injections are given regardless of food intake.

The correct dosage and duration of treatment is a very important point when using the medicine Ceraxon. The dosage for children, as well as the course of therapy, are prescribed strictly by the attending physician. It is strictly forbidden to independently change the dose of the drug and the frequency of its use, as this may affect the child’s well-being and the progression of his illness. The following is a table with approximate doses of Ceraxon for children of different ages:

Method of administration and dosage of Ceraxon in children

"Ceraxon" is one of the popular nootropic drugs. It is widely used in neurological practice, prescribed to adults for strokes and brain injuries, since its effectiveness is high for various lesions of the central nervous system. Sometimes this drug is used in children, but only as prescribed by a specialist.

Analogues of the drug

After using the drug "Ceraxon", reviews indicate great success of treatment, however, this medication, in turn, also has the following analogues:

In the form of an injection solution - medications “Escotropil”, “Cerebrolysin”, “Cerebrolysate”, “Lucetam”, “Amilonosar”.
In the form of tablets - Omaron, Noopept, Memotropil, Pantogam, Memoplant, Lucetam, Cavinton, Gopantam, Ginos, Vincetin, Vinpocetine, Vero-Vinpocetine", "Acephen", "Amilonosar".
In the form of capsules - drugs “Piracetam”, “Neuromet”, “Carnicetine”, “Idebenone”, “Noben”, “Ginkoum”.
In the form of sublingual tablets - Glycine.
In the form of a solution that needs to be taken orally - the drugs “Nootropil”, “Cogitum”, “Demanol”, “Tanakan”, “Nooclerin”.
In the form of a dry extract – Cortexon;
In the form of nasal drops – medications “Semax”, “Minisem”.

Pregnancy

There are no sufficient data on the use of citicoline in pregnant women. Although animal studies have not shown any negative effects, during pregnancy the drug

prescribed only in cases where the expected benefit to the mother outweighs the potential risk to the fetus.

When prescribing Ceraxon during lactation, women should stop breastfeeding, since there is no data on the excretion of citicoline in human milk.

Opinions of patients and doctors

Reviews of Citicoline (1000 mg) are usually positive. People report increased effectiveness from drug therapy during recovery from stroke and traumatic brain injury, as well as for disorders that are associated with vascular lesions of the brain.

But there are also responses with complaints about the occurrence of adverse reactions. In many situations, such as dizziness, insomnia, migraine, agitation.

Most medical specialists leave good reviews about Citicoline. Noting a remarkable combination of levels of increased effectiveness and very rare development of negative effects.

When rehabilitating people who have suffered a stroke, it is necessary to choose the right medication to restore brain function. In their practice, doctors often use Citicoline. In a medical facility, the drug is used in the form of injections, which allows you to quickly eliminate ischemia at the source of the lesion and neurological signs.

In addition, there are reviews of Citicoline (1000 mg), in which doctors say that patients with alcohol and drug addictions need to use nootropic medications as additional treatment. Citicoline helps restore cognitive functions, as well as memory and concentration.

Adverse reactions

According to the instructions for use, it is known that Citicoline very rarely provokes negative actions. But still they sometimes happen:

Excitation.
Hyperstimulation of the parasympathetic nervous system.
Insomnia (sleep disorder, which is characterized by shallow sleep, as well as a delay in its onset or early awakening).
Hallucinations (an image that appears in consciousness without an external stimulus).
Vertigo (a disease better known as dizziness; it is characteristic of ear diseases or, less commonly, of brain lesions).
Headache.
Numbness in paralyzed limbs.
Arterial hypotension (lowering blood pressure by more than twenty percent).
Hypertension (a disease whose main symptom is an increase in blood pressure caused by nervous and functional disorders).

How to prepare a suspension from the contents of the sachet

In order to prepare the cerakson sachet suspension, you should separate one sachet from the other along the tear seam

Holding it vertically, carefully tear off the edge along the o. After opening, the contents of the sachet should be diluted in half a glass of water and drunk before meals or between meals.

Get examined and treated with Ceraxon by making an appointment with a neurologist at the Yusupov Hospital by phone. The contact center of the Yusupov Hospital is open 7 days a week, around the clock. Leading specialists in the field of neurologists individually select the optimal doses, course of treatment and pharmacological forms of drugs.

Author

Boris Yuryevich Bobrov

Endovascular surgeon, Candidate of Medical Sciences. Laureate of the Russian Government Prize in the field of science and technology, laureate of the Vocation Award. The largest personal experience of EMA in Russia

Pharmacology

Due to the main substance, the drug has a nootropic effect and has a wide spectrum:

enhances cholinergic type transmission in the brain of the head;
regenerates membrane areas of cells;
inhibits phospholipase action;
stops the formation of active oxygen molecules without a paired electrode (free radical);
reduces the number of damaged cells in the brain of the head during a stroke (acute);
inhibits and stops neurological symptoms in cases of traumatic brain injury, and also shortens the duration of post-traumatic coma.

The use of “Ceraxon” in a sachet, according to reviews from medical experts, is particularly effective in the treatment of neurological disorders (motor or sensory) that are of vascular or degenerative origin.

During oxygen starvation (hypoxia) of chronic brain tissue, the drug produces good results in the treatment of cognitive disorders (lack of initiative, memory impairment, difficulty performing self-care activities). The instructions for using Ceraxon in a 1000 mg sachet say that taking the medicine slows down the manifestations of amnesia and increases attentiveness.

This product is well absorbed. Metabolism occurs in the liver and intestinal tract with subsequent formation of cytidine and choline. After entering the body, the active substance enters the brain and is embedded in the membranes of cells of the cytoplasmic and mitochondrial type. Excretion occurs in a small volume (approximately 15%), 3% in urine and 12% in exhaled air.

Instructions for use of Ceraxon in sachets and other forms

The drug in the form of a sachet is used 20 minutes before or after meals. To prepare the suspension, you need to open 1 sachet, first separating it from the rest. Then the contents are dissolved in 50 ml of water and drunk. The dosage of Ceraxon in a sachet should not exceed 2-3 sachets of medicine in 24 hours. The exact dosage for treatment is determined by the doctor depending on the patient’s problem.

The drug in the form of an oral solution can be taken both during and after meals. It is pre-diluted in a small amount of water without gas (maximum 100 ml can be used). During the day, take 1 g twice. The duration of treatment is determined by a neurologist (usually it lasts no more than 10 days).

When using the oral solution, the sequence must be followed (to use a special syringe).

It is necessary to immerse the syringe vertically into the bottle with the drug.
By pulling the piston up, you should draw the required amount of liquid.
It can be dissolved in a small amount of warm still water or consumed undiluted.
After administration, the syringe must be thoroughly rinsed and dried. After this, it can be collected for further use.

According to the instructions, the tablets can be taken regardless of meals. The maximum dosage is 4 tablets. The number of appointments is individual for each patient.

The injection solution is used in several ways. It can be administered intravenously, intramuscularly and intravenously. All manipulations are carried out by a nurse in a medical institution.

Compound

The active component of the drug is citicoline sodium, which has the following properties:

has a stabilizing effect on the membrane;
reduces cerebral edema;
weakens the severe symptoms of cerebral dysfunction resulting from injury or acute circulatory disorders in the brain;
helps reduce the level of amnesia, etc.

Depending on the form of release of the drug, the main substance is supplemented with auxiliary components that improve the absorption of the drug by the body.

The list of components used by the manufacturer includes:

sorbitol;
methyl parahydroxybenzoate;
glycerol;
sodium citrate dihydrate;
propyl parahydroxybenzoate;
sodium saccharinate;
potassium sorbate;
strawberry flavor (strawberry essence 1487-S-Lucta);
citric acid (50% solution);
purified water.