Ketanov tablets instructions for use. Ketanov analogues. Ketanov tablets

Composition and release forms of Ketonal

The active ingredient of the drug is ketoprofen and, depending on the form of release of the drug, it is present in it in a certain dosage (see table).

Dosage form of the drug Ketonal	Ketoprofen concentration
Injections (injection solution)	50 mg/ml
Capsules	50 ml
Long acting tablets	150 mg
Cream (also called ointment)	5 %
Gel	2.5% (or 2.5 mg)
Film-coated tablets	100 mg
Suppositories for rectal administration	100 mg

There are also Ketonal Duo and Uno capsules, the content of the active ingredient in which is 150 and 200 mg, respectively. Most forms of the drug are intended to be taken or administered orally, as this option provides the most effective therapeutic effect.

Pharmacological action of the drug

The three therapeutic effects that Ketonal injections provide are pain relief, reduction of inflammation and relief of fever. The last action is not as pronounced as the first two. At the molecular level, the analgesic effect of the drug is explained in this way - ketoprofen blocks the activity of enzymes involved in the synthesis of the main provocateurs of pain and inflammation - prostaglandins.

A special feature of the drug Ketonal is its wide spectrum of action. In this regard, it is used to relieve pain of various origins and localization. Thus, the remedy is effective against pain in muscles, joints, blood vessels, ligaments, skin and many organs. For arthritis, the remedy relieves pain and helps reduce swelling and stiffness that occurs in the affected areas in the morning.

What is better ketanov or ketorol What are the differences between ketorol and ketanov

So, both drugs are positioned as well-known anti-inflammatory and pain relievers. They have similar names. Both drugs have one main component – ketorolac. It is used in various doses. In ketanov, the dose of the main component is higher than in ketorol. What is stronger and more effective: ketanov or ketorol? Ketanov is the most serious remedy aimed at pain relief.

Both of these drugs are produced in tablet form. Thanks to the strong concentration of ketorolac, ketanov is suitable for relieving the most severe pain. This medicine is often prescribed for joint pain. Ketanov is also effective for pain during menstrual periods.

For headaches, it is advisable to use ketorol, because its effect is the mildest. For acute migraine, ketanov is recommended. The advantage of ketorol is that it is most harmless for pregnant women and nursing mothers.

With the highest efficiency, ketanov has more contraindications than ketorol.

So, what to choose: ketanov or ketorol? The choice depends on the type of pain. For acute, sharp pain, it is recommended to use ketanov, for minor injuries and pain - ketorol. It acts more gently and has fewer contraindications.

Possible side effects that occur during treatment

This medicine may cause unwanted side effects in some cases. The list of them is quite impressive, but it is worth saying that in medical practice they are rarely recorded and, as a rule, are associated with improper use.

The drug can affect the nervous system, causing headaches, increased drowsiness, and dizziness. Paresthesia, convulsions and distortion of taste sensations are much less common. Sometimes patients also complain of tinnitus and blurred vision.
Possible side effects from the digestive system, including nausea, vomiting, stool disorders, bloating. Much less frequently, therapy leads to the development of gastritis, exacerbation of Crohn's disease, and the appearance of gastrointestinal bleeding.
Side effects include allergic reactions, which include hives, skin rashes, itching, and swelling. Anaphylactic shock develops much less frequently.
During therapy, disturbances in the functioning of the respiratory system may occur, including nosebleeds, bronchospasm, severe rhinitis, asthmatic attacks, and laryngeal edema.
Sometimes there is an increase in the level of liver enzymes and bilirubin.
Possible impairment of kidney function up to renal failure.
Other side effects include fatigue, swelling, weight gain, hypertension, and hemorrhagic anemia.

If any deterioration occurs, you should immediately stop therapy and report your symptoms to your doctor.

special instructions

Your doctor will tell you why Ketonal tablets help. Pills, as noted earlier, can be washed down with milk, or antacids in the form of Almagel, Maalox, and Phosphalugel are also suitable. These substances do not affect the absorption of the active ingredient "Ketonal", but help reduce the likelihood of complications and adverse reactions from the digestive system. With prolonged use of this medication (more than one week), you will need to regularly donate blood to monitor liver and kidney function.

You need to especially carefully monitor such criteria when taking the drug “Ketonal” by elderly people over sixty-five years of age.

The medicine in question must be used with great caution if a person has hypertension and cardiac pathologies that are associated with edema. In such cases, blood pressure must be constantly monitored throughout the course of using the medication.

Indications for use

Ketanov is indicated both in tablets and in injections for the relief of pain of various origins and localization. Indications, as a rule, are exactly the same for different dosage forms, but the choice of one form or another depends only on ease of use. Since pain is a symptom of many diseases and conditions, it is necessary to highlight only those for which this drug can be taken.

Ketanov shown:

To relieve pain during the postoperative period.
For pain relief in case of traumatic injury to muscles, soft tissues and bones. For example, for fractures, bruises, sprains, dislocations.
To eliminate rheumatic pain, pain due to osteoarthritis, osteoarthritis.
For pain resulting from withdrawal of narcotic analgesics.
For toothache and various dental diseases (caries, pulpitis, periodontitis).
For renal and biliary colic.
For pain during the postpartum period.
For muscle pain.
For osteochondrosis.

Ketanov for rheumatoid pain

Rheumatoid arthritis is a serious disease that is characterized by severe pain and inflammation of the joints. This disease must be treated immediately, from the moment of diagnosis. Therapy for rheumatoid arthritis includes several methods, one of which is to reduce pain with special drugs from the group of non-narcotic analgesics. It is these medications that are first aid for severe joint pain. One of these medications is Ketanov, which in this case helps not only to reduce pain, but also to eliminate the inflammatory process in the joints and periarticular tissues.

However, it must be remembered that Ketanov can be taken for rheumatoid arthritis only as prescribed by a doctor and in a certain dosage. You need to know that if you take a particular medicine correctly, you can significantly reduce the risk of side effects.

Interaction with other drugs

If Ketanov is taken in parallel with other medications, this may cause complications or lead to a decrease in the analgesic effect

Here is a list of the main interactions to look out for:

It is forbidden to take Warfarin together with Ketanov. Otherwise, the analgesic effect will decrease to 97 percent. Also, you should not drink digoxin, heparitis and other salicylates at the same time;
Use together with acetylsalicylic acid. It is not recommended to combine two drugs, as there are risks of side effects;
Use of Probenecid. When taken in parallel, the effect of Ketanov is reduced. Doctors do not recommend combining these drugs;
Taking Cyclosporine. May lead to nephrotoxic side effects. Not used together with Ketanov;
Concurrent use of Oxpentifilin. This leads to the development of dangerous hemorrhage;
Use together with Mifepristone. The effect of this drug will completely disappear if you start taking Ketanov;
Concurrent use of drugs with lithium is prohibited;
Use of anticoagulants. If taken together with Ketanov, this leads to the risk of bleeding. Simultaneous use is strictly contraindicated.

If you take the drugs described above in parallel, this can lead to dangerous side effects and a deterioration in your general condition. It is imperative to tell your doctor what medications you are currently taking so that he can adjust your therapy.

Contraindications

There are absolute and relative contraindications for using the drug. This means that there is a list of situations in which the drug cannot be used at all, and there are diseases or conditions that have their own application characteristics. Therefore, it is necessary to go to see a doctor and consult with him whether this drug can be used.

The following are absolute contraindications to the use of analgesic drugs based on ketorolac:

intolerance to this medicine or others in the group;
a history of aspirin-induced asthma;
bronchospasm;
dehydration;
hypovolemia;
exacerbation of stomach ulcers;
liver failure;
problems with blood clotting;
angioedema;
frequent bleeding or its high probability;
severe renal failure;
problems in the hematopoietic system;
hemorrhagic diathesis;
stroke;
childhood;
pregnancy, lactation;
chronic pain syndrome, etc.

In all these cases, taking ketorolac is prohibited, so if you have a history of these diseases, you should not even think about purchasing and using this drug.

The list with relative contraindications is no less numerous in terms of the number of items. It includes the following diseases or problems of the body:

bronchial asthma;
arterial hypertension;
heart problems (chronic heart failure);
cholecystitis;
cholestasis;
sepsis;
hepatitis in the active phase;
systemic lupus erythematosus;
neoplasms in the form of polyps in the nose and pharynx.

Precautionary measures

Ketanov should not be used to eliminate abdominal pain, as this leads to a distortion of the clinical picture of an acute disease requiring surgical intervention.

When planning an operation or examination, it should be taken into account that the effect of the drug on blood clotting disappears one to two days after the last dose. Canceling Ketanov three days before the expected manipulation will avoid bleeding during surgery and distortion of test results.

If a patient has been diagnosed with bleeding disorders, or has recently undergone surgery, then during treatment with medication it is necessary to monitor the number of platelets in the blood. Ketanov is best taken in a minimal dose.

If side effects occur, especially from the gastrointestinal tract (gastrointestinal tract) and circulatory system, you should discontinue the medication.

Ketanov often provokes such negative consequences as dizziness and confusion, so it is better to avoid driving a car and working with complex mechanisms.

Interaction with other drugs

Ketorol is almost one hundred percent bound to plasma proteins and does not change the pharmacokinetics of other medications.

The following features of interaction with certain medications can be highlighted:

NSAIDs (non-steroidal anti-inflammatory drugs), aspirin, glucocorticosteroids, drugs containing calcium - there is a high probability of developing ulcerative lesions of the gastrointestinal tract and bleeding;
paracetamol – increased nephrotoxicity is observed; simultaneous use for more than 5 days in adults and 2 days in children is not recommended;
probenecid – the concentration of ketorolac increases, the half-life increases;
insulin - the effect is enhanced;
methotrexate – increased toxicity;
diuretics and drugs to lower blood pressure - effectiveness decreases;
anticoagulants (including heparin), thrombolytics, cefotetan - high risk of bleeding;
opioid analgesics – dose reduction required;
antacids – no effect on drug absorption is observed;
morphine, promethazine - it is forbidden to mix with Ketanov in one syringe;
Tramadol, lithium cannot be prescribed together.

Use during pregnancy and lactation

NSAIDs can have an effect on the heart and blood vessels of the fetus, so the use of Ketanov while expecting a baby is not allowed, especially in the last trimester. The product is not used for pain relief during labor and labor.

The drug is contraindicated for nursing women, as it may adversely affect the health of the baby. If treatment with Ketanov is necessary, breastfeeding will have to be abandoned.

Prescription in children and the elderly

The medication is allowed to be used only by persons over 16 years of age. However, in case of urgent need, for example, in case of unbearable pain, it can be used in children from two years of age. The dosage should be selected individually, based on the calculation - 1 mg per 1 kg of weight. It is better not to use the drug in a course, but to limit it to a one-time administration to relieve pain.

Ketanov should be used under the supervision of a specialist and with great caution in elderly patients, since in them ketorolac is eliminated longer and its plasma clearance is reduced. Minimum doses are recommended for such patients

Solution in ampoules

The instructions indicate that ampoules with Ketorol solution are completely ready for use; the doctor prescribes their use in a certain dosage, which is prohibited from being exceeded. To relieve pain, intramuscular injections are usually indicated in the gluteal region, and less often in the thigh or shoulder. If the doctor has not determined the individual dosage, then for a single administration you can use from 1 to 3 ampoules, taking into account the severity of the pain.

The dosage of Ketorol solution for injections, as an NSAID, is designed for the age group up to 65 years. If a patient switches from injections to tablets, you should carefully consider the total daily dose:

For patients in the age group up to 65 years	the daily dosage should not be more than 90 mg
For patients over 65 years of age	the dose is reduced to 10-15 mg administered every 4-6 hours

Contraindications for use

For some patients, it is strictly forbidden to use Ketanov as an anesthetic. The drug will not relieve the unpleasant symptom and will only harm your health. Here are the cases in which doctors do not recommend taking the medicine:

Allergy to any component in the tablets or solution;
If the patient has an active ulcer;
With bleeding in the stomach;
At the time of peptic ulcer disease;
Dangerous for bronchial asthma;
Not prescribed for angioedema;
For rhinitis;
Dangerous for urticaria;
Not used before surgery and during manipulation of blood vessels;
Dangerous if the heart fails;
If polyps occur in the nose;
For bronchospasm disease;

Not prescribed for Quincke's edema;
Dangerous for postoperative patients who have previously had frequent bleeding;
Not prescribed for contractions in pregnant women;
When using other painkillers;
Dangerous for hemorrhagic diathesis;
If the patient has bleeding disorders.

Taking Ketanov in such cases can cause severe complications and worsening pain. It is imperative to consult a doctor before taking this painkiller and inform the doctor about all past diagnoses. It is best to undergo diagnostics, which will help identify hidden disorders in the body.

Indications for use

Ketanov in any form (tablets or ampoules) is used to relieve pain of various origins or nature. As a rule, the form of release of this drug does not affect the effectiveness of treatment; the patient most often chooses whether it would be more convenient for him to use tablets or use ampoules intramuscularly.

The range of uses of ketanov is very wide, because pain occurs in various diseases, so cases of use of ketanov should be described in more detail. Ketanov is often prescribed for headaches.

Why does ketanov help? Ketanov medicine is used in the following cases:

For pain in the teeth (for example, removal of wisdom teeth);
For headaches;
For joint pain;
Reducing pain after various operations;
After various injuries to muscles, soft skin and bones (fractures, ruptures, bruises, sprains, dislocations);
For renal colic:
With otitis media;
After visiting the dentist;
For muscle pain;
In the postpartum period;
For pain from tumors;
Various disorders of the spine:
Osteochondrosis;
During painful critical days;
Radicular syndrome.

It is not advisable to use Ketan medicine for discomfort in the gastrointestinal tract, because it can hide the signs of various dangerous diseases that require urgent surgical intervention.

It is important to remember that this drug only masks pain and symptoms, but does not cure them, so if you experience regular pain, you should consult a doctor.

Analogs

A substitute for a particular drug may have the same active ingredient as the main one (then it is a synonym), or it may coincide with it in its mechanism of action, but contain a different active substance (this is an analogue).

Among the synonyms of Ketanov solution are:

Dolak;
Dolomin;
Ketalgin;
Ketorol;
Ketorolac.

The drug's analogues are as follows:

Biolan;
Voltaren;
Diklak;
Diclofenac;
Ortofen.

Ketanov solution has long established itself as an effective and fairly safe remedy that is used for pain of various etiologies. The obvious advantage of the drug is that it is not addictive and lasts a long time

However, it is important to remember that when using any medication, you must undergo examination and consult with your doctor.

Composition of ketanov

In ketanov, the main component is ketorolac. It is contained both in solution in ampoules and in tablets. Ketorolac is added to ketans in different doses, which is influenced by the form of release. A tablet of this product contains ten mg of ketorolac, and one ampoule contains thirty mg per ml.

In ketanov in the form of tablets, the additional substances are:

Light yellow powder, which is extracted from natural raw materials (corn starch);
Silicon(IV) oxide;
Mineral from the silicate class (talc);
Water;
Ethylene glycol polymer;
Magnesium salt;
Stearic acid:
Microcrystalline cellulose.

The following substances are used as additional substances in the composition of ampoules for injections:

Table salt or sodium chloride;
Water;
Caustic soda;
Ethanol;
Edetate disodium.

After reading this list of components, it becomes clear that certain substances can cause allergies.

Before using tablets (injections), it is advisable to consult a doctor and carefully read the instructions for use, which are available for ketanov in different release forms.

Analogues of Ketanov

Reviews of Ketanov claim that the drug is the most effective among similar medications. Moreover, the drug begins to relieve pain faster. An analogue of Ketanov is a non-narcotic drug with an anti-inflammatory effect.

Drugs similar in effect to this one include:

Dolak;
Adolor;
Ketolac;
Ketorol;
Voltaren;
Diclovit;
Diclofenac;
Toradol.

At the moment, Ketanov is considered the most powerful medicine. No means have yet been invented that have such a quick effect with less risk of developing negative consequences.

Ketanov or Ketorol - which is better?

The main differences between Ketanov’s analogue and the drug described in the article:

Toradol or Ketanov – what to choose?

The active ingredient in Toradol is ketorolac tromizamine.

The drug is sold in the form of tablets (10 and 20 capsules each) and injections (5 ampoules of medication per package).

Like Ketanov, the medication is used once or twice in a row. Its goal is to temporarily stop severe and moderate pain symptoms.

The side effects of Toradol coincide with those that appear with Ketanov. Stomatitis and loss of healthy skin color are also possible.

Ketanov or Dolak – which is cheaper?

Like Ketanov, Dolak has two forms of release - tablets and injections.

Capsules are sold in 10 or 20 pieces per package. The injection preparation contains 30 milligrams of the active ingredient in one ampoule. The package contains 10 containers.

Side effects are similar to those that occur during Ketonov therapy and may occur more frequently.

Dolak is also one of the strongest painkillers in this category.

Prices are approximately half that of Ketanov:

20 tablets of Dolak will cost 30-40 rubles;
10 ampoules cost close to 70-80 rubles.

Side effects

In practice, side effects were observed infrequently. They were mainly associated with an independent increase in the dosage calculated per day or in case of violation of the Ketonal administration technique. May also occur due to personal hypersensitivity to the composition of which the patient was not aware

However, caution is still necessary and be sure to consult with the doctor supervising you. Do not decide on your own which medications you need.

Negative reactions can be expressed in the form of:

Headaches;
Dizziness;
Increased drowsiness;
Blurred vision;
Noise in the ears;
Nausea;
Incorrect sensations of taste;
Vomiting;
Bloating;
Abnormal stool;
The occurrence of gastritis;
Gastrointestinal bleeding;
Cramps;
Exacerbation of Crohn's disease;
Skin allergies (swelling, itching, rash);
Bleeding from the nose;
Nasal congestion;
Laryngeal edema;
Breathing disorders;
Asthmatic attacks;
Anaphylactic shock.

Any non-standard reaction of the body must be recorded. Treatment for negative reactions can only be inpatient and will be the same as for overdoses. Symptoms of overdose are usually accompanied by vomiting and nausea, and abdominal pain. Disturbances in consciousness, difficulty breathing, and convulsions may occur.

It is treated with medication to eliminate negative symptoms and remove ketoprofen from the body. Withdrawal occurs with special inhibitor drugs and prostaglandins.

Trouble, what to prepare for

As can be seen from the instructions for the Ketanov tablets, the drug can provoke negative responses from the body, some of which occur in three patients out of every hundred, but most side effects develop in only one percent of patients or even less often. One of the most common reactions is headache. Many people complain that during the course they constantly feel sleepy and feel dizzy. With a probability of 1-3%, meningitis of an aseptic nature may develop, expressed by convulsions, headaches, and muscle rigidity. There is a risk of depression or increased activity associated with mood swings and anxiety. There are cases where, while taking Ketanov, psychosis developed and hallucinations were observed.

Also in the instructions for Ketanov tablets, the manufacturer draws attention to the possibility of disruption of stool and gastrointestinal tract function. This is observed to a greater extent in persons 65 years of age and older, suffering from ulcers, erosion

Possible abdominal pain, vomiting, jaundice. Rarely, "Ketanov" provokes a runny nose, laryngeal edema, bronchospasm, problems with the functioning of the kidneys and urinary system. Some patients experience an increased frequency of the urge to urinate. There are known situations where taking medication provoked fainting, increased blood pressure, ringing in the ears and bleeding, and allergic reactions.

How to take the pills

Ketanov tablets can be taken directly to relieve pain or taken according to a specific schedule. To relieve acute pain, it is recommended to take 1-2 tablets before meals, so the therapeutic effect will occur faster, however, a detrimental effect on the gastrointestinal mucosa is possible. If the pain is not severe, you can take the tablet after a meal, swallowing it whole. It is not recommended to bite or chew the drug! After taking it, you need to drink about 100 ml of still water.

If you take the drug after a fatty meal, the therapeutic effect may occur a little later. In addition, the medicine can be taken according to a specific schedule, that is, take 1-2 tablets 3-4 times a day every 6-8 hours, regardless of whether there is pain or not. In this case, the daily dosage according to the schedule should be no more than 8 tablets. The duration of therapy is determined by the doctor, individually for each patient. As a rule, treatment lasts from 5 to 7 days.

Ketanov during pregnancy and lactation

This medicine is strictly prohibited during pregnancy and breastfeeding. If a woman is indicated to take Ketanov during lactation, then the child must be switched to artificial feeding while taking the medicine.

What happens in the body

“Ketanov” is intended to relieve pain, at the same time suppress inflammatory processes, and inhibit the activity of cyclooxygenase. Almost immediately after entering the human body, the drug is completely absorbed into the circulatory system. The rate of adsorption may decrease slightly if the drug enters the body with food, but this fact does not affect the degree of efficiency of the process. The maximum concentration of the active compound in the circulatory system is observed half an hour or an hour after taking the tablet. If you use the solution for intramuscular administration, the interval is from 45 minutes to one hour.

The pharmacokinetics of Ketanov are linear, the plasma concentration of the active compound is similar to the dose received by the patient. There is no cumulative effect. The equilibrium concentration is fixed 6 hours after the drug enters the body. The component binds to plasma proteins by 99% or higher. The substance may cross the placenta. Medical research has found it in human breast milk. Up to 90% of the incoming medication leaves the body through the urinary system, of which 60% is unchanged. The half-life on average is from 4 to 6 hours from the moment the tablet is ingested.

Ketanov release form

The drug ketan is produced exclusively in two forms:

Ampoules for intramuscular injections;
Pills.

Ketan tablets also differ: they are produced either in a regular shell or in a film shell. The clinical effect of these types of tablets is almost identical, therefore, when prescribing tablets, the differences for patients are insignificant. Tablets are produced in ten, twenty and one hundred pieces per pack. The packaging itself is white with a yellow corner.

The solution for injection (into the muscle) is usually called ketan injections or ketan ampoules. In fact, we are talking about a solution. The ketane solution is produced in 1 ml ampoules of 5 or 10 pieces.

Ketanov is not produced in the form of ointments or suppositories. Other medications containing the active substance ketorolac are produced in ointment or gel forms, for example, ketorol gel.

Method of application and dose of ketanov

The main symptom for using ketanov is pain of various origins. There are no fundamental differences in the use of tablets or ampoules in the instructions for use.

Ketan injections or tablets are allowed to be used systematically for some days. If the patient has chosen a systematic solution, then the tablets are used every five to six hours, just like injection ampoules.

If the patient chooses to take it as needed (during the onset of pain), then the tablet is taken once during the onset of pain. The duration of treatment with Ketanov should not exceed the following norm:

Adults are advised to use this treatment for no more than five days;
For children, treatment is recommended for no more than two days.

When using tablets, they must be swallowed completely with an average amount of water. It is advisable to use ketan tablets after meals, this will reduce the likelihood of a bad effect on the mucous membranes. After a fatty meal, the effect may occur later. If the patient needs a quick effect, then ketan tablets should be taken before meals.

Ketanov can be used one-time (if pain occurs) and on a schedule. The schedule is recommended to be no more than five days for an adult. You need to take one tablet three or four times a day every 6-7 hours. For severe pain, you can take tablets in double dosage - two tablets per dose.

People under 50 kilograms, over 65 years old and with impaired kidney function need to take ketan tablets in halved doses.

Ketanov ampoules should be injected deep into the muscle during the injection. The best places for injections into the muscle: upper arm, abdomen, thigh.

It is undesirable to inject into the buttocks, since they contain dense fatty tissue. With it, the solution does not always get into the muscle, which causes the effect of the drug to slow down and weaken.

The selected injection site must be disinfected. Because the ampoule contains 1 ml of solution, then for the correct dose it is advisable to use a small syringe of 0.5 - 1 ml. You need to use a needle to insert deep into the muscle.

The dose of ketanov for injection is prescribed personally based on the type and frequency of pain. The solution, like Ketanov tablets, can be used once in connection with the onset of pain and on a schedule.

For people under 65 years of age and without renal failure, injections are prescribed at a dosage of 10-30 mg (0.1 - 1 ml). For people with impaired renal function, the dose of ketanov is reduced by half. The course of injections is equal to a week.

Dosage of the drug in the form of a solution

Ketanov in the form of an injection solution is prescribed intramuscularly. To relieve the first attack of pain, 10 mg of the drug must be administered. After 5 hours, the dosage should increase to 30 mg. The attending physician should supervise the administration of the medication.

The maximum dose of Ketanov per day is no more than 90 mg. Elderly patients should be administered no more than 60 mg of the drug.

Injections with the drug are allowed for 2 days to relieve pain. After this, the patient can take Ketanov tablets for another 5-7 days until the pain symptoms completely disappear.

After the first injection, the unpleasant pain goes away within 30 minutes. Complete pain relief will occur within 2 hours. The doctor must change the dosage based on the patient's diagnosis and general condition. To reduce the likelihood of side effects, do not prescribe too high a dose.

Use during pregnancy and lactation

Ketanov in any form is contraindicated for use during pregnancy and breastfeeding.
Its use during pregnancy can be resorted to only for health reasons on the part of the mother. If Ketanov is indicated for a nursing mother, then during the period of its use the woman should switch the child to artificial formula. During childbirth, Ketanov should also not be used for pain relief, since the drug prolongs labor and weakens the contractile activity of the uterus, which can cause serious complications, including bleeding.

Women who are forced to use Ketanov during pregnancy should not worry too much, since animal experiments have not revealed any negative effects of the drug on the fetus. However, late labor and post-term pregnancy were observed in females receiving Ketanov.

Contraindications

This Ketanov drug has various limitations that should be taken seriously.

Cases in which you should not use ketans:

For chronic diseases;
If you are under sixteen years of age;
If kidney function fails;
If you are intolerant to any substance in ketanov;
When recovering from a stroke;
For gastritis;
With enlarged pancreas.

It is necessary to use ketans with care for erosive and ulcerative lesions of the gastrointestinal tract (especially during exacerbations)

After consulting a doctor, you can use ketans with caution for blood pressure, asthma and heart failure.

It is not recommended to use ketans for pain in the abdominal area, because the effect can smooth out the symptoms of dangerous diseases that require treatment.

Ketanov should be discontinued three days before surgery to avoid increased bleeding, because When consuming ketanov, a decrease in blood clotting is observed.

If a rash or other deterioration appears while using ketanov, this remedy should be discontinued.

The drug ketanov has various contraindications, so it is advisable to consult a doctor before using it.

Ketanov in any form is prohibited during breastfeeding and pregnancy. If Ketanov is recommended for a nursing woman, then she needs to switch to feeding with various mixtures.

Ketanov should not be used during childbirth to relieve pain, because this will only increase the time of labor (the contractile activity of the uterus will weaken). There is a possibility that during childbirth, ketanov will provoke bleeding. If ketanov is still prescribed during pregnancy for some individual indication, then it should be used under the supervision of a doctor.

You cannot combine ketanes and alcohol. When interacting, they increase the chance of ulcers and internal bleeding from the gastrointestinal tract.

Alcoholic drinks enhance the analgesic effect of ketanov, because of this you may not notice an increase in pain.

Contraindications and side effects

Ketanov can cause the development of side effects, which manifests itself in disruption of the functioning of the central nervous system. In this case, the risk of headaches, drowsiness and even lethargy increases, which is a consequence of a decrease or increase in blood pressure.

There is a detrimental effect on the digestive organs, since there is a high probability of developing peptic ulcers, toxic type hepatitis and gastritis. The first signs are vomiting, nausea, sharp pain in the abdomen and defecation disorder. At the time of using Ketanov, it is advisable to stop driving vehicles.

pregnancy and lactation;
bronchial asthma;
gastritis with high acidity;
peptic ulcer, the presence of chronic renal and liver failure;
various bleedings;
toxic hepatitis, liver cirrhosis.

It is advisable not to combine Ketanov with other representatives of the group of non-steroidal anti-inflammatory drugs. These include Nurofen, Aspirin and Indomethacin, as well as Analgin.

What does Ketanov help with?

Before taking the drug, you need to understand the uses of Ketanov. Ketanov's action includes pain relief (ketan's analgesic effect is the strongest), relieving inflammation and reducing temperature in diseases.

The product, according to the instructions for use, has the following method of therapeutic action: as soon as the active substance is taken and it enters the blood, cyclooxygenase is immediately blocked and the production of prostaglandins, which are responsible for the inflammation process, is inhibited. All pain mediators cease to be released and act thanks to the use of Ketanov, from which it helps to overcome toothache, relieve pain during inflammation, and avoid many complications.

Ketanov has a very wide application - its effect relieves symptoms of pain of various types and places of origin. A more detailed list of indications is given below:

to relieve pain after surgery;
for initial assistance in case of various injuries (dislocations, bruises, sprains, fractures);
if a tooth starts to hurt, but there is no way to quickly get to a dental facility so that the doctor can help and relieve the aggravation (they take regular Ketanov, since there are no tablets specifically for toothache);
use the drug before long dental procedures;
if the pain is caused by impaired renal function (renal colic, renal failure);
postpartum pain;
otitis;
with cholelithiasis;
The drug is taken in long courses in case of osteoarthritis and osteoarthritis;
some guidelines recommend this analgesic for pain relief in tumors;
An equally common indication is osteochondrosis.

Pharmacodynamic properties of the anesthetic

What pharmacodynamic properties do the drug in question and its analogue have? "Ketanov" (tablets and injections) has a pronounced analgesic effect. The drug has moderate antipyretic and anti-inflammatory properties.

According to experts, the principle of action of this medication is associated with inhibition (non-selective) of the activity of the enzymes COX-2 and COX-1. This process occurs in peripheral tissues. This effect causes inhibition of the biosynthesis of PGs, that is, modulators of thermoregulation, pain sensitivity and inflammation.

The use of Ketanov tablets or the administration of an intramuscular solution promotes the formation of a racemic mixture of S- and R-enantiomers. By the way, the analgesic effect of the drug is due only to the S-form.

It should be especially noted that this medication does not depress breathing, does not affect opioid receptors in any way, does not have an anxiolytic or sedative effect, and does not cause addiction.

What do you need to know before taking this product or its analogue? "Ketanov" (tablets and injections) in terms of the strength of its analgesic effect is comparable only to morphine. According to experts, this drug is significantly superior to all other non-steroidal drugs.

After oral or intramuscular administration, the analgesic effect is observed after an hour and half an hour, respectively. The maximum effect of the drug is achieved after 60-120 minutes.

Ketonal's analogs

Ketoprofen.
Ortofen.
Diclofenac.
Ketanov.
Movalis.

Ketoprofen and Ketonal - what is the difference?

The main active ingredient in both drugs is ketoprofen. These agents have an almost identical mechanism of action, but in order to make the right choice, you should familiarize yourself with their differences.

Ketonal and Ketoprofen are presented in the same release forms, except that the first product is manufactured in Slovenia or by a German organization, and its opponent is produced by Russian companies, Vertex.
Ketoprofen is safer for children; in pediatrics it is prescribed from 6 years of age. Ketonal cannot boast of such an advantage; it is more suitable for teenagers.
The cost of the analogue ranges from 70-180 rubles, and the price of Ketonal is higher.

What to choose, Ketonal or Ketoprofen, depends on the desires of the consumer. The analogue is cheaper, therefore, it is considered more affordable. Those who trust European production more than domestic ones, Ketonal is suitable. In addition, the German drug causes fewer side effects.

Flamax or Ketonal - what to choose?

Flamax, like Ketonal, belongs to a number of non-steroidal anti-inflammatory drugs based on propionic acid. The active substance is ketoprofen. These funds have a number of differences.

Flamax has the same effects as Ketonal, but this product has higher absorption and bioavailability (90%).
An analogue is produced in Russia, and Ketonal is produced in Germany. The cost of Flamax is 100-150 rubles, which is cheaper than the opponent.
Contraindications and side effects are the same for both drugs.
Flamax is produced in the form of ampoules, capsules, tablets, rectal suppositories, and Ketonal has a wider selection of production forms.

To eliminate pain due to pathologies of the musculoskeletal system, preference should be given to Ketonal, the drug has a stronger antispasmodic effect.

Ketanov and Ketonal - which is cheaper?

Both drugs are not considered full-fledged analogues, since they have a number of significant differences.

Ketanov and Ketonal have different active ingredients, in the original it is ketoprofen, and the opponent includes ketarolac in its composition. Despite this nuance, both elements are comparable in effectiveness to morphine; Ketonal is evacuated from the body faster and has fewer side effects. Due to this nuance, the drug is prescribed to older people.
Ketonal can be used in conjunction with other medications at minor oral dosages.
Ketanov's action begins 40 minutes after internal administration, and reaches its maximum effect after 2 hours, and its brother is famous for the same.
Ketonal is more effective for eliminating long-term pain in a chronic form.
Ketanov is produced in India, its cost ranges from 70 to 250 rubles, depending on the form of release. This is slightly cheaper than the price of Ketonal.

If you choose between these drugs, you should rely on your doctor’s recommendations. Note: Ketanov has a more powerful analgesic effect, while his opponent has an anti-inflammatory effect.

Ortofen or Ketonal - what to choose for osteochondrosis?

Ketonal and Ortofen have the same effect, but their similarities end there.

Ketonal has a stronger effect on severe pain due to diseases of the musculoskeletal system; the product allows you to quickly relieve discomfort without harming the articular cartilage. The medicine is inferior in power to Ortofen, this medicine is more effective in inflammatory processes.
Both drugs are rarely used in pediatrics. Ortofen is manufactured in Kharkov, Ukraine. Cost - from 40 to 170 rubles, depending on the form of release. In terms of price, Ketonal's analogue is cheaper.
Ortofen has a large list of side effects, they occur more often than after using Ketonal.

If you choose between Ketonal and Ortofen for pain caused by diseases of the musculoskeletal system, it is better to give preference to the first remedy. Ortofen is more suitable for eliminating inflammation. Lovers of European quality will appreciate Ketonal, and admirers of domestic production will appreciate Ortofen.

pharmachologic effect

The drug Ketanov has a pronounced anti-inflammatory and analgesic effect, and also has a moderate antipyretic effect. Ketorolac (active substance) suppresses the activity of group I and II cyclooxygenase enzymes, prevents the synthesis of arachidonic acid, and stops the formation of prostaglandin, which is a provocateur of febrile conditions, pain and inflammation. Compared to other drugs of similar action, Ketanov has several important advantages:

does not interfere with the functioning of the respiratory system;
does not reduce the number of platelets in the blood, nor does it reduce their activity;
does not have a negative effect on the psychomotor skills and mental state of the patient.

Thus, a highly effective drug is used as an anti-inflammatory and analgesic for any degree of pain intensity. In this regard, Ketanov is far superior to other drugs belonging to the same group (NSAIDs), and its anesthetic properties are similar to the effects of morphine.

The effect of the medication begins 30-40 minutes after taking it, and the maximum effect is achieved after two hours. When taken orally, ketarolac is instantly absorbed into the blood through the gastrointestinal tract, however, the presence of food in the stomach, especially fatty foods, slows down the absorption process, so the maximum concentration of the active substance in the blood is observed only an hour after taking the medicine. When administered intramuscularly, the peak activity of the drug is observed after 30-40 minutes.

The drug is eliminated from the body through the work of the kidneys and liver. 5-6 hours after administration, its concentration in the body is about 50%. In patients suffering from kidney disease, as well as in elderly patients, the removal of the drug from the body takes longer (usually from 12 to 14 hours).

Basic information about the medication

Ketorol belongs to the group of drugs NSAIDs (non-steroidal anti-inflammatory drugs), a class of derivatives of pyrrolysine-carboxylic acid. Any form of the drug has an analgesic and anti-inflammatory effect with signs of a moderate antipyretic effect. However, after using Ketorol injections, the analgesic effect is much stronger and occurs faster, unlike other types of medication.

Gel. A homogeneous transparent substance, used externally, has a characteristic odor, packaged in tubes of 30 g.
The tablets are greenish in color, biconvex in shape, packaged in packs of 20 pieces. A distinctive feature of Ketorol tablets is the presence of the letter “S” on one side.
Ampoules (glass) of 1 ml with a solution for intramuscular and intravenous administration are equipped with a recess for breaking and a ring. The package contains 10 ampoules.

Pharmacological properties

Ketanov is a non-steroidal anti-inflammatory drug.

It has the following medicinal properties:

Blocks pain syndrome
Relieves inflammation
Reduces temperature

The degree of action of the drug varies. The main purpose is pain relief. It copes well with any pain. But as for reducing temperature or anti-inflammatory properties, they are much weaker. Doctors explain this by the fact that the strong analgesic effect overshadows the other effects of the drug. Compared to other strong painkillers, the effect of Ketanov is tens of times greater.

It is important to remember that Ketanov is a non-narcotic drug and, accordingly, is not addictive, but it does have a negative effect on the nervous system. In the group of non-steroidal drugs, Ketanov is considered the strongest. Ketanov is equally effective in relieving pain in all organs and systems of the human body.

Doctors use it to block severe pain. The secret of Ketanov's action is that ketorolac binds cyclooxegenase, an enzyme that provokes inflammation, fever and pain.

Ketanov equally effectively relieves pain in all organs and systems of the human body. Doctors use it to block severe pain. The secret of Ketanov's action is that ketorolac binds cyclooxegenase, an enzyme that provokes inflammation, fever and pain.

When Ketanov acts on the body, it binds substances that are responsible for sensitivity to pain

It does not matter what factor provokes pain, because Ketanov does not treat or destroy the source of pain. This drug copes well even with long-term and painful pain.

Previously, in medicine, strong opiates such as Morphine or Omnopon were used to relieve acute and long-term pain. But the number of side effects in them far exceeded the beneficial qualities, and opiates are narcotic drugs that cause addiction, unlike analgesics.

Ketanov does not cause the following symptoms:

Does not have a sedative effect
Does not depress breathing
Does not irritate the central nervous system
Does not interfere with the functioning of the heart muscle
Does not change pressure readings

Medicines with similar effects

If necessary, Ketanov can be replaced with other drugs of similar action. The most commonly prescribed drug substitutes are:

Methindol;
Dickloberl Retard;
Ketorol;
Rapten;
Ketalgin;
Ketolac;
Zerodol;
Ketonal / Ketonal Duo;
Ketorolac.

Judging by the reviews of patients who use non-steroidal drugs to relieve pain, the drug Ketonal is most similar to the main drug, characterized by a rapid onset of effect, but its period of action is shorter than that of Ketanov tablets.

The price for the Ketanov painkiller is quite affordable and does not exceed 110-125 rubles per ampoule or 54-65 rubles per pack of tablets. Available without a prescription.

Ketanov is a potent anti-inflammatory and anesthetic drug used in the treatment of many diseases, the course of which is accompanied by severe pain. However, you should not prescribe and use this remedy yourself, since in this case the risk of developing serious complications increases. It is better to consult a doctor who will determine an individual treatment regimen and dosage.

Too much

You can suspect an overdose of a medication by painful sensations in the abdomen. Often the situation is associated with vomiting and nausea. Excess Ketanov in the body can cause peptic ulcers and lead to impaired renal function. If the situation does not repeat itself, after stopping the medication, all negative changes will resolve themselves.

If negative symptoms of overdose appear, means should be used to relieve unpleasant symptoms. No special therapy is required. Dialysis is also ineffective because it does not remove the active compound from the patient's blood.

Ketanov instructions for use of tablets

There is no fundamental difference between taking drugs in tablets and injections. Moreover, a prescription for Ketanov is required in both cases. The patient decides together with the doctor which form to take.

The tablets should be taken whole, with as much water as possible. The ideal time to take your next dose is when you have finished eating. After eating, the gastric mucosa does not react so negatively to the anti-inflammatory drug, so vomiting and other side effects characteristic of Ketanov are not observed. If you take fatty foods, the expected effect often occurs much later, sometimes by an hour.

The easiest way to use Ketanov is a one-time dose when there is pain. If the problem arose once and began to resolve on its own, you can stop taking the product for the day. But there is another way, which involves using the drug 4 times a day with a daily dose of up to 8 tablets. The scheme is as follows: assess how severe the pain is, and if its manifestations are weak, take one tablet of the drug 3-4 times a day, and if severe, take 2 tablets with the same frequency.

How long can you take Ketanov? As the description indicates, no more than a week. After this, the side effects increase significantly.

Dosage

According to the instructions, Ketonal tablets to eliminate pain are taken in the following standard dosage:

Regular coated pills are taken one at a time twice a day.
Long-acting tablets are used once a day.

The maximum permissible daily dosage for all types of medication is 200 milligrams. The duration of therapy is strictly individual, and it is determined by the speed of relief from pain. That is, the medication is taken as needed against the background of pain and used until it is completely relieved. The dosage of Ketonal tablets must be strictly observed.

It is worth saying that this drug is suitable for long-term use in the presence of pain syndromes of different localization. The tablets should be taken with an equal interval between two subsequent uses, which will ensure reliable relief from existing discomfort and contribute to a minimal risk of complications. For example, if regular pills need to be taken twice a day, then it is best to take them within an interval of ten to twelve hours, and those that have a prolonged effect are optimally taken daily at the same time .

Ketonal tablets can be taken in combination with rectal suppositories, as well as cream or gel. However, it is necessary to ensure that the total daily dosage of the active ingredient in all forms used does not exceed 200 milligrams. When taking this medication, you should remember that the drug does not cure the disease, but only eliminates painful symptoms, allowing the patient to work fully and lead a normal lifestyle. In this regard, in combination with Ketonal, it is imperative to carry out the necessary therapy aimed at completely eliminating the disease.

How can you replace ketans for toothache?

The presence of a number of contraindications to the use of ketanov, the danger of negative consequences of using this medicine is the reason why a doctor’s prescription is required to purchase the drug in a pharmacy. What to do if there is no prescription for ketanov or there are contraindications to it?

A common pain reliever is nimesil and its analogues. This drug can be purchased without a doctor's prescription. Unfortunately, it does not work as effectively as ketone. At the same time, it is more effective and less dangerous than the still widely used analgin. In addition, unlike analgin, nimesil lowers the temperature and relieves inflammation.

The advantage of Nimesil is that it can be taken not only by adults, but also by children. Drugs for toothache Tablets for toothache Analgin for toothache Ketanov for toothache Nise for toothache Nimesil for toothache Analogues of Nimesil Diclofenac for toothache Took for toothache pain Ketonal for toothache Nurofen for toothache Mig for toothache Ibuprofen for toothache Paracetamol for toothache Spazmalgon for toothache Tempalgin for toothache Citramon for toothache Aspirin for toothache Pentalgin for toothache Ketorol for toothache Folk remedies for toothacheMore Analgesics stronger than nimesil, like ketone, require a doctor's prescription.

How to use?

To minimize the risk of side effects, it is important to use the drug strictly in accordance with the instructions for Ketanov tablets. Incorrect use and overdose significantly increase the risk of a negative response from the body, including unpredictable and severe reactions. The manufacturer advises using one capsule of the drug at a time. Can be repeated no more than 4 times per day, that is, the maximum daily dosage is 40 mg of the active compound.

Slightly different restrictions are provided for the product in the form of a solution. The substance should be administered into muscle tissue in the minimum dosage that shows the desired effect. In each individual case, the doctor chooses the dose individually, focusing on the strength of the pain syndrome and the patient’s response. If the situation is very severe, Ketanov can be combined with opioid painkillers.

Characteristics of Ketonal

This is a non-narcotic, non-hormonal drug, characterized by antipyretic, anti-inflammatory and analgesic properties. It helps relieve moderate and severe pain of various origins, for example, with colic, neuralgia, myalgia, radiculitis, osteoarthritis, spondylitis, arthritis, etc.

Dosage forms of Ketonal:

pills;
gel;
cream;
rectal suppositories;
solution in ampoules for intravenous or intramuscular administration;
capsules.

The main active component of the drug is ketoprofen. This substance belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDs). A distinctive feature of the drug is the provision of a wide range of analgesic effects, distributed to the peripheral and central nerve fibers that are responsible for the perception of pain impulses. Therefore, Ketonal is often used for pain in joints, muscles, and ligaments. The drug reduces inflammatory reactions, which helps relieve pain in joint diseases and relieves morning stiffness.

Tablets, injections, suppositories and capsules are prescribed for the treatment of degenerative or inflammatory diseases of cartilage, ligaments, muscles, joints and bones:

rheumatoid arthritis;
glenohumeral syndrome;
rheumatism;
gout and pseudogout;
osteochondrosis;
osteoarthritis;
arthrosynovitis;
periarthritis;
polyarthritis;
reactive arthritis;
ankylosing spondylitis;
psoriatic arthritis.

To relieve pain, doctors often prescribe drugs such as Ketonal or Ketorol.
In addition, these dosage forms are prescribed to relieve severe or moderate pain in the following diseases and conditions:

phlebitis;
lumbago;
lumbodynia;
sciatica;
radiculitis;
neuralgia;
myalgia;
headache;
bursitis;
tendinitis;
lymphadenitis and lymphangitis;
pain after operations, injuries, during menstruation and malignant tumors.

Gel and ointment are indicated in the following cases:

periarthritis and rheumatoid arthritis;
neuralgia;
myalgia;
bursitis, tendinitis;
osteoarthritis;
reactive arthritis;
psoriatic arthritis;
ankylosing spondylitis;
ruptures of tendons and muscle ligaments, sprains, bruises of ligaments and muscles, injuries to the musculoskeletal system;
radiculitis.

Contraindications for Ketonal include:

intolerance to drugs of the NSAID group;
bleeding disorders;
exacerbation of inflammatory bowel diseases (enteritis, Crohn's disease, etc.);
exacerbation of a stomach or duodenal ulcer;
chronic digestive disorders (constipation, diarrhea, flatulence, etc.);
bleeding of any location (uterine, gastrointestinal, etc.);
coronary artery bypass grafting performed less than 2 months ago;
heart failure;
progressive kidney disease;
severe liver or kidney failure;
third trimester of pregnancy;
breastfeeding;
children under 15 years of age.

Contraindications for Ketonal include: intolerance to NSAIDs, blood clotting disorders.
Cream and gel should not be applied to wounds on the skin (wetting dermatitis, eczema, open wound, etc.).

Painkiller Ketanov

According to the pharmacological classification, the drug Ketanov is a non-steroidal drug with antirheumatic and anti-inflammatory effects. This means that it relieves pain syndromes and relieves inflammation. The active ingredient of the drug is ketorolac tromethamine, which has a pronounced analgesic effect.

Composition and release form

Ketanov is available in the form of tablets and solution for injection. The detailed composition of each medicine is given below:

Pills	Solution
Description	Covered, round	Transparent, colorless, pale yellow liquid
Active substance concentration, mg	10 per 1 pc.	30 per 1 piece.
Compound	Corn starch, microcrystalline cellulose, water, macrogol, silicon dioxide, talc, hydroxypropyl methylcellulose, magnesium stearate	Sodium chloride, alcohol, water, sodium edetate, sodium hydroxide, hydrochloric acid
Package	10, 20 or 100 pcs. in a pack	5 or 10 ampoules of 1 ml per pack

Pharmacological properties

Nonsteroidal anti-inflammatory drug (NSAID) belongs to pyrrolysine-carboxylic acid derivatives, has analgesic, anti-inflammatory and moderate antipyretic effects, stimulates opioid receptors. The mechanism of action is associated with inhibition of the enzyme metabolizing arachidonic acid, which is a precursor of prostaglandins. These substances cause inflammation, pain and fever.

Oral administration of the drug allows the active substance to be absorbed by the walls of the stomach and intestines and reach maximum concentration in the blood plasma after 45 minutes (parenteral administration has a similar time). Eating does not affect the absorption of the drug; it is 99% protein bound. The active substance is excreted after 4-10 hours in the urine and intestines. With impaired renal function or in the elderly, the withdrawal time is increased.

Indications for use of Ketanov

The instructions for use indicate the indications for use of the drug - this is short-term relief of moderate and severe pain of the following origin:

postoperative bleeding (after abdominal, orthopedic, gynecological operations);
for dislocations, fractures, soft tissue damage;
toothache after dental surgery;
postpartum period, oncology;
osteoarthritis, sciatica;
not used for chronic pain.

Ketanov for stomach pain

As with any other pain, Ketanov helps with abdominal pain, but according to doctors, this is not recommended. The reason is the negative effect of the drug on the mucous membrane of the digestive tract. If abdominal pain is caused by pathologies of internal organs, the use of the medicine is prohibited, since relief of the syndrome will delay a visit to the doctor and increase the risk of complications. You can use tablets if the pain is short-term and occurs after surgery.

Ketanov for menstrual pain

For most women, menstrual pain is caused by spasmodic contractions of the uterus, which are caused by prostaglandins. If the patient does not have problems with the genital area, a bent uterus or hormonal disorders, Ketanov effectively copes with pain by blocking the production of substances that interfere with the normal movement of blood through the vessels of the genital organs.

For toothache

The active component ketorolac is known for its strong analgesic effect by inhibiting the production of prostaglandins. Once inside, it acts systemically, and not just on toothache. The drug helps with severe pain, which goes away in 35 minutes, and the effect lasts up to seven hours . Due to its antipyretic effect, the analgesic can be used for severe inflammation from pulpitis or periodontitis.

Ketanov. Action

This is a fairly strong non-steroidal anti-inflammatory drug. The principle of its action is that it slows down the action of the cyclooxygenase catalyst and blocks the synthesis of prostaglandins. In addition, Ketanov does not have a sedative effect, which has a very positive effect on the life of patients.

Which one is better, when and for whom?

If you are in doubt about choosing one of these products, you should be guided by the following factors:

Intensity of pain and presence/absence of inflammation and elevated body temperature.
The presence of concomitant diseases of organs and organ systems that are targets for side effects (liver, auditory analyzer, cardiovascular system, excretory system, etc.).
General condition of the body (for more weakened patients, especially in the elderly and senile, it is advisable to use lighter drugs due to the lower likelihood of side effects of the drug, for example, peptic ulcers of the stomach, dysfunction of the liver, heart, kidneys, etc.).
The presence of absolute indications for the use of Ketorol or Ketonal, which were described above.
Individual tolerance to the components of one and another drug (presence of allergic manifestations).

Thus, we can draw a simple conclusion that Ketorol and Ketonal are very similar, but at the same time have a number of serious differences, which once again confirms the need to carefully study the drugs before independent use, provided that you are fully aware of the condition of your body.

Nowadays, most of us think that there is no need to seek help from doctors for every reason. After all, there is a medicine for every disease, be it stomach pain or cough. Most often, people carry painkillers with them, such as Ketonal and Ketanov. What is the difference between them, we will tell you in more detail in order to know exactly the features and properties of each drug.

Most common adverse drug reactions

Since the drugs belong to the same pharmacological group, their side effects are mostly the same:

Stomach upset;
Increased fatigue;
Headaches and dizziness;
Weight gain;
Swelling of the arms, legs and face;
Heavy sweating.

In some cases, the patient may experience abdominal pain and vomiting. Depending on the cause of the symptoms, there is an increase in blood pressure, accompanied by severe shortness of breath and hearing dysfunction. In addition, allergic rhinitis and urticaria may occur.

With excessive use of tablets, an overdose may occur, which is manifested by vomiting, hallucinations, drowsiness, and in case of severe poisoning, a stomach ulcer may develop.

Overdose

Adult patients need to take one suppository twice a day.

Suppositories "Ketonal" can be used in conjunction with other drugs that contain ketoprofen. However, the maximum amount of this substance taken per day should not exceed 200 mg.

Using more than 2.5 g of ketoprofen can cause overdose symptoms: abdominal pain, nausea, vomiting, drowsiness.

There are no antidotes for medications that contain ketoprofen. For those who are poisoned by the drug, the stomach is washed and supportive and symptomatic treatment is prescribed to compensate for dehydration.

If the patient has renal failure, hemodialysis is indicated, due to which the drug is completely removed from the blood.

Reception scheme

For toothache Ketanov take 1 tablet per day. It does not matter when the drug is taken (before or after meals). Also, the period of time that has passed since the next meal does not matter. If the pain worsens again, then you need to take another tablet after 5-6 hours. If the doctor has allowed children under 12 years of age to take tablets, then a single dosage of the drug for this category of patients will not exceed ½ tablet.

The solution is administered intramuscularly only to those patients who have reached 16 years of age. It is allowed to use no more than 2 ml of solution at a time. For people with kidney pathologies and older people, the maximum dosage of Ketanov does not exceed 1 ml. The interval between injections is also 5-6 hours.

The frequency of taking the medication depends on the severity of pain symptoms:

for moderate pain, take 1 tablet every 12 hours;
for acute unbearable spasms, consumption of 4 capsules per day is allowed.

Despite the fact that Ketanov has a powerful effect, after its consumption it is not recommended to exert mechanical force on the tooth. Otherwise, the pain syndrome may worsen again. Also, you should not take the drug immediately before going to the dentist. It can distort the clinical picture of the disease (for example, when determining the stage of caries) and contribute to the incorrect diagnosis.

The drug should be discontinued on day 5. Failure to comply with this rule increases the likelihood of developing side effects from the gastrointestinal tract. It is necessary to consult a doctor for toothaches even if Ketanov has completely relieved the pain symptoms. There is a high probability that the symptom will make itself felt in the near future with greater intensity.

The drug in the form of a solution is rarely used to eliminate symptoms of dental problems. It is used to relieve muscle spasms. You can learn more about the methods of administering the solution in the instructions for use.

Effect of the drug

Like other propionates, ketoprofen works by affecting the enzymes COX1, COX2. It does not have a selective effect, therefore it affects all foci of the presence of these substances that are involved in the production of prostanoids (prostaglandins and other mediators of pain and inflammation). The result is suppression of enzyme production and a decrease in the inflammatory response, which occurs both locally and in the central nervous system and hypothalamus.

Ketonal also acts in a different way. It suppresses the production of bradykinin, a substance that dilates blood vessels, which is one of the factors responsible for pain sensitivity. Inhibiting the release of this peptide also reduces pain. The medicine also affects leukotrienes - these substances cause spasms, trigger allergic-inflammatory reactions, also participating in inflammation. Administration of Ketonal provides the following effects:

analgesic;
anti-inflammatory;
decongestant;
antipyretic.

By stabilizing liposomal membranes, the use of the drug helps reduce cell damage that occurs during inflammation. The active substance penetrates well into the synovial fluid without damaging articular cartilage. It is easily absorbed from the small intestine with a bioavailability of 90%, the peak concentration is detected after 1.3 hours, and is not affected by food intake. When administered intravenously, the maximum effect develops within 20 minutes. The medicine is excreted by the liver, which imposes restrictions on therapy for diseases of this organ.

Advantages

Ketanov has a powerful anesthetic effect for toothache, which lasts for a long period of time. Among NSAIDs, you cannot find another drug with a similar effect. A person can achieve a more pronounced therapeutic effect only by taking steroid painkillers. For this reason, Ketanov is prescribed even for unbearable toothaches associated with postoperative complications and traumatic factors.

Blocking prostaglandins also makes it possible to stop signs of inflammation and fever.

The therapeutic effect of Ketanov is equal to the drug Nise

Ketanov can be included in the list of the best painkillers because it:

does not affect the cells of the central nervous system;
does not provoke digestive disorders in the form of vomiting and stool disorders;
does not increase heart rate;
is not addictive;
relieves severe pain, in which other NSAIDs are powerless;
has a long-lasting analgesic effect (up to 8 hours);
dispensed without a doctor's prescription;
affects pain of various localizations.

Pharmaceutical action

The drug has a complex effect on the human body:

anti-inflammatory;
antipyretic;
painkiller.

The medicine does not affect the central nervous system of patients and their moral state. The active component begins to act immediately after entering the blood. It stops the production of prostaglandins, which are responsible for the perception of pain. After taking the tablets or administering the solution, a person ceases to feel not only toothaches, but also spasms of other localizations.

The effect of taking Ketanov is observed after 30-40 minutes and lasts for 5-8 hours. How long it takes for Ketanov to take effect largely depends on its release form, the intensity of pain in a person and the patient’s individual susceptibility to medications.

The components of the drug are excreted along with urine, so it is not recommended to drink it for people who have problems with kidney function. Ketanov is excreted in the urine in the form of metabolites.

It is a non-steroidal medication that relieves inflammation. Provides an analgesic effect.

The therapeutic process is carried out due to the inhibition of the enzyme cyclooxygenase and prostaglandins.

It does not have a sedative effect on opiate receptors, does not depress breathing, does not impair the functioning of the nervous system or motor processes.

The pills are absorbed fairly quickly. Their highest concentration in the blood is achieved approximately 40 minutes after morning use on an empty stomach. In this case, you need to give up high-carbohydrate and fatty foods, as this will significantly reduce the therapeutic speed, delaying it for 1 hour.

After administration of the solution, it concentrates in the blood at a maximum level in 20-60 minutes.

Most of it is excreted by the kidneys, and the rest by the intestines in 5 hours. This value is increased in older people and, conversely, decreased in young patients.

They are extremely rare. However, failures may occur:

Spheres of digestion in the form of nausea, difficulty in emptying, gastritis, ulcerative lesions of internal organs, dry mouth;
Central nervous system - craving for rest, sleep, dysfunction of the vestibular apparatus, nervous tension, spontaneous goosebumps, tingling and burning sensations;
Urinary systems – frequent urination, kidney dysfunction, nephritis;
Metabolic processes;
Blood pressure level;
Pulse rate;
Hematopoiesis - reduced platelet levels, purpura, frequent nosebleeds, decreased concentration of potassium ions in the blood;
Dyspnea;
Allergies – rashes on the skin.

Patient opinions

The vast majority of those who have used Ketonal speak extremely positively about the various forms of the drug.

Svetlana, 20 years old: “I injured my back while playing sports and now periodically experience severe pain. I tried to take many painkillers, but Ketonal became a real salvation for me!”
Igor, 48 years old: “Ketonal-gel was recommended to me after I severely sprained the ligaments in my leg. The drug helped, now I always keep it in my medicine cabinet, just in case.”
Marina, 36 years old: “After gynecological surgery, I experience severe pain during menstruation. Only taking Ketonal Duo helps to forget about them. “I have never experienced any side effects.”

Features of use for children, pregnant women and during breastfeeding

Ketanol is contraindicated during pregnancy, breastfeeding, and children under 16 years of age.

The drug Ketanov is not recommended for use by pregnant women. The constituent components have a harmful effect on the child. Also, you should not use the medicine during childbirth.

Since the constituent components are excreted in breast milk, the drug is not used during breastfeeding.

Important! Contraindicated for use in children. Ketanov can only be used by adults and adolescents over 16 years of age. Sometimes in exceptional cases it is used for children from 2 years of age.

Features and Cautions

Pregnant and lactating women

In the first and second trimester, Ketonal is prescribed only in cases where the benefit to the mother outweighs the risk to the child. The third trimester suggests a complete ban on this drug, since ketoprofen can cause late and complicated labor. If taking Ketonal is necessary during breastfeeding, then the child is transferred to artificial formula.

Mechanism control

Ketoprofen does not directly affect the ability to control complex mechanisms or devices that require attention and reaction speed. But it is still not recommended to use it in such cases, since the list of side effects of the drug includes disorders of the nervous system.

Interaction with other drugs

Injections and other forms of Ketonal reduce the effectiveness of Mifepristone, diuretics and blood pressure lowering drugs, but enhance the effect of hypoglycemic medications (to reduce blood sugar levels).

In combination with other NSAIDs (Diclofenac, Aspirin, Ketorol, etc.), alcohol and glucocorticosteroids, it can provoke gastrointestinal bleeding. Impaired renal function is possible when Ketonal is taken simultaneously with diuretics and ACE inhibitors (Enalapril, Captopril, etc.). The risk of bleeding increases when ketoprofen is combined with any antithrombotic drugs, be it anticoagulants, thrombolytics or antiplatelet agents. When ketonal is combined with cardiac glycosides, Methotrexate, lithium preparations or calcium channel blockers, the blood concentration of these drugs increases.

Important instructions

Capsules and tablets can be taken with antacids such as Almagel, as well as milk, since they do not affect the rate of absorption and at the same time reduce the risk of developing complications from the gastrointestinal tract.

Long-term use of Ketonal (injections and other forms) involves monitoring the composition of the blood and the state of the kidneys and liver, especially for older people.

The drug should be used with caution and under the supervision of a doctor for hypertension and heart disease.

Reviews

Doctors with many years of experience strongly advise using this drug. At the same time, experts remind that before taking tablets or intramuscular injection of a solution, it is imperative to visit a medical institution, undergo an examination, after which the patient will be prescribed a treatment regimen according to the established ailment.

Evgenia. 35 years. Ekaterinburg.

One day, when I fell at work, I severely damaged the soft tissues of my back. In addition to many gels and other remedies, the doctor prescribed Ketanov for me. It can be used both internally and in the form of injections. But fearing the latter, I decided to buy pills. Having started taking them, I began to recover so quickly that I didn’t even notice how my sick leave ended.

Ivan. 23 years old. Bryansk.

Ketanov helped me during the summer session at the university. Then, I experienced simply unbearable toothache, which not only did not allow me to prepare for exams, but also to sleep, since it intensified at night. Having suffered until the morning, in the hope that everything would pass, I went to the nearest pharmacy, where I was recommended this inexpensive drug.

After drinking it, after a few hours I felt a complete cessation of all existing symptoms. Apprehensively preparing for the night, I took another pill in the evening. As a result, I didn’t even notice how I fell asleep. Now I recommend this pharmaceutical product to everyone. Its main advantage is fast and long-lasting pain relief and affordable cost.

Anton, 37 years old. Ketanov toothache tablets act quickly and help eliminate spasms for several hours, but you should not abuse them. If you experience pain, you should contact your dentist as soon as possible.

Irina, 41 years old. At the dacha I got a toothache. I couldn’t see a dentist because I was too far from the city. The pain was so severe that it radiated into the ears and eyes. I took the only painkiller that was in my first aid kit – Ketanov. The product relieved the pain within 15 minutes and allowed me to spend the weekend at the dacha without any problems. I got an appointment with a doctor only 4 days later. The dentist said that I acted irresponsibly, because Ketanov has a lot of side effects.

Vitaly, 38 years old. I can’t speak unequivocally about the drug. I only used it once, when I damaged the root of a tooth. I took it as a preventive measure so that I wouldn’t feel pain later. However, my injury was not accompanied by pain. This drug does not help my brother at all. He says it also hurts to chew food and drink. I think you shouldn’t count on a special therapeutic effect from the drug for serious problems. It's better to go to the dentist right away.

Danger and consequences

The general combination of alcohol and Ketanov causes a negative consequence. The drug negatively affects the functioning of the nervous system. There is inhibition of reactions and brain activity. The liver is also affected. The gland bears the heaviest toxic load.

Possible consequences

The main negative from mixing Ketanov with alcohol occurs in the intestines and fermentation. While drinking alcoholic beverages, it is forbidden to resort to medication. The interaction enhances the destructive effect of toxins and provokes unwanted side effects. Parallel intake of two substances activates protective functions. As a result, the ions pass into the mucous material of the stomach and destroy it from the inside. The substances interfere with tissue regeneration and restoration of the structure of blood vessels.

To protect the affected areas, the body begins to produce fermentation. The collision of opposing elements contributes to the occurrence of inflammation. Alcohol increases the likelihood of resulting side effects and acute gastrointestinal diseases. Combining alcohol with medicine causes:

increased sensitivity of cells and organs to the therapeutic effects of the drug;
the opposite effect, causing intoxication of the body instead of a medicinal effect;
overdose of the drug if the recommended dose is observed;
reducing the number of enzymes that neutralize the negative effects of the drug;
metabolic disease.

According to the warnings described above, you should avoid the general use of Ketanov with alcohol. This will protect you from many health problems. With general use, there is a high probability of worsening the effect of the drug. Consequences that are life-threatening to the patient develop.

Adverse reactions

Alcohol significantly enhances the side effects of the drug. The likelihood of serious consequences for patients with pathologies in the gastrointestinal tract increases. Symptoms appear after a period of time. Common consequences are:

gagging, feeling of nausea, pain in the abdominal area, diarrhea, bloating;
development of ulcerative lesions, gastritis, duodenitis;
kidney disease, swelling, frequent urination;
hepatitis, jaundice;
irritability, drowsiness, dizziness;
changes in blood pressure;
manifestation of allergies in the form of urticaria, unbearable itching.

The interaction of alcoholic beverages and Ketanov increases the presence of toxic substances in the body. As a result, the patient faces life-threatening consequences. The greatest danger is:

hemorrhage in the stomach and intestines;
liver and kidney failure;
hallucinogenic images, mental disorder;
anaphylactic shock;
bronchospasms.

httpv://www.youtube.com/watch?v=embed/SGAUPw4Z_aA

To prevent the onset of complications, you will have to give up the simultaneous use of alcohol and the drug Ketanov, especially for those suffering from gastrointestinal diseases. During therapy, it is recommended to stop interacting with alcoholic beverages. The period between their treatment must be maximized. This way, the expected results from the procedures are achieved and the risk of side effects is reduced.

Stories from our readers

Saved the family from a terrible curse. My Seryozha hasn’t drunk for a year now. We struggled with his addiction for a long time and unsuccessfully tried a lot of remedies over these long 7 years when he started drinking. But we made it through, and thanks to everyone.

Pain is a defensive reaction aimed at preserving the integrity of the body and the functionality of its organs. But not every pain is that same defensive reaction. There are types of pain that can literally drive you crazy. The best way to get rid of pain, naturally, is to eliminate the cause that causes it. But if this is not possible, analgesics or painkillers come to the rescue.

Ketanov is a representative of the most common group of analgesics - non-steroidal anti-inflammatory drugs. Compared to narcotic analgesics, it does not depress the brain and is not addictive, but exhibits a powerful analgesic effect. There are situations in life when a person’s pain occurs against the background of complete well-being, sometimes during or after a feast with alcoholic beverages. To find out whether the combination of Ketanov and alcohol is dangerous, you need to understand the mechanism of action of the medication and the possible interaction of these substances.

How can ketanov be dangerous for toothache?

Like any other drug, ketanov can cause side effects if overdosed, taken for too long, if the rules of administration are not followed, and if there are contraindications. Possible negative consequences of taking ketanov include: Allergies - from small rashes to swelling, breathing problems and even anaphylaxis.

Disturbances in the normal functioning of the digestive system - constipation, gas formation, nausea, vomiting. Hypertension. Neurological problems - headaches and dizziness, emotional swings, depression. An overdose of the drug also causes kidney pathologies. If too large a dose of medicine was taken, the victim should rinse the stomach and give an adsorbent.

To prevent the use of ketanov from leading to negative consequences, you need to know when this drug should not be used. Firstly, ketanov is incompatible with a number of substances. These include: drugs containing calcium and lithium; other non-steroidal anti-inflammatory drugs; aspirin;

ethyl alcohol; glucocorticosteroid drugs; corticotropin; paracetamol; heparin and other drugs that prevent blood clotting. The incompatibility of ketanov with alcohol is due to the fact that the simultaneous presence of ethanol and the drug in the body leads to overload of the liver, which finds it difficult to cope with both substances.

As a result, on the one hand, alcohol intoxication increases, and on the other hand, the likelihood of side effects of the drug increases. Secondly, in some cases, ketane is contraindicated for patients. Contraindications to the use of this drug include: pregnancy; breastfeeding; allergic reactions to the drug.

Breastfeeding women should not drink ketan because it passes into breast milk. It is unacceptable for this drug to enter the body of an infant. In addition, ketones should not be used in the presence of pathologies such as: peptic ulcer or duodenal ulcer; pathologies of the liver and kidneys;

bronchial spasms; cerebral hemorrhage. Ketanov should also not be taken by patients who have recently undergone a surgical operation. For pain that continues for a long time, Ketanov should also not be taken. Since the maximum duration of use of the drug is no more than a week, pain relief with its help will only be a temporary solution to the problem.

Limitations: continuing the list

Since the drug in question is one of the rather strong medications with a pronounced effect, there are many contraindications regarding the possibility of its use. In particular, as can be seen from the instructions for use, Ketanov pain relief tablets are not intended for those suffering from dehydration; aspirin is not used to relieve pain during surgery, since the use of the medication increases the risk of bleeding. Normally, the drug is not used for the treatment of minors. Of course, sometimes a doctor can give instructions on the use of Ketanov tablets for children, but there is no official information about the absence of negative consequences for such patients, no studies have been conducted.

Rules for taking capsules

Capsules should not be bitten or chewed. They are swallowed whole, along with the shell, washed down with plenty of liquid. As a rule, ordinary water is used for these purposes. Drink Ketonal with food or immediately after taking it.

Use on an empty stomach is also not prohibited, but then unpleasant and painful sensations may occur.

Treatment rules:

Frequency of administration – up to 3 times a day.
Single dosage – 1 capsule (if necessary, the quantity can be increased to 2 pieces).
Stop taking when the required result is achieved.

The frequency of taking Ketonal Duo and Uno is once a day.

When will it help?

All indications for use are clearly stated in the instructions for Ketanov tablets (10 mg - dosage of the active compound). Doctors recommend having a remedy on hand to relieve pain. The medication is effective for sensations provoked by a variety of factors, and helps even with intense pain. It is also reasonable to use it for pain of moderate intensity.

As can be seen from the instructions for use, Ketanov tablets help relieve pain caused by malignant neoplasms. Sometimes the product is used for severe toothache. The medication can be used during the rehabilitation period after surgery if the patient has a difficult recovery.

Who is not prescribed

This is written in the instructions for Ketanov injections. Cellular blisters contain 10 tablets. The price of Ketanov is low - a package costs about 100 rubles. How it is used can be read in the description of the medicine.

According to special regimens with a reduced dosage, Ketanov is prescribed to elderly people, patients with chronic disorders of the liver and kidneys, as well as patients with arterial hypertension.

When Ketanov is combined with paracetamol, intoxication may occur. Among Ketanov's analogues, there are no products completely identical to it. Ketonal is most similar to it. Ketanov is not prescribed to children.

In case of acute toothache, you should first try to relieve it with weaker remedies (rinse with a soda solution, brush your teeth with medicated paste). If they are powerless, and an immediate visit to a doctor is impossible, you can take Ketanov. According to the instructions, you can take one tablet after meals. If it is not possible to eat before taking, you can take the pill with milk.

Unfortunately, in some people this drug can cause a lot of unpleasant phenomena in the body. Ketanov + alcohol" will deal a severe blow to your liver. I also took solpadeine with tempalgin before - no effect. And this medicine really helped me. I found out that my liver is not 100% healthy, and the doctor warned me not to get carried away with this painkiller. Yes, the drug is very effective, but it is not designed for course use. Think about your health, don’t get carried away with this medicine. However, you should not get carried away with this medicine.

Injections are given only intramuscularly, this process is painful.

After assessing the victim’s condition, the emergency doctor will provide him with symptomatic treatment and, if necessary, hospitalize him.

These are drugs from the same pharmaceutical group, so it’s quite difficult to say which is stronger. Differences between Ketanov and Ketonal? Why do I take this particular analgesic with me?

These substances are largely responsible for pain, and therefore, when their amount decreases, the pain weakens, or even goes away altogether. And in case of toothache, taking this medicine is perhaps the best way to solve the problem. If there is no impact on the tooth, the pain will be almost completely absent. It is recommended to use this drug regularly for at most five days. During this time, it is highly advisable to make a visit to the dentist. Ketanov should also not be taken by patients who have recently undergone surgery.

Repeated use of the drug is allowed no earlier than four to six hours after the first dose.

In order to overcome attacks of pain, strong analgesics are used. On one side there must be an engraving “KVT”. This drug also exists in the form of an injection solution. Its components act primarily on peripheral tissues. Enzymes that are responsible for pain are blocked. At the same time, it is superior even to morphine in terms of pain relief. The peak of its analgesic activity occurs an hour or two after administration.

The pain syndrome described above does not need to be endured - it must be gotten rid of first.

In what cases should Ketanov not be taken?

Like any other medicine, Ketanov has a number of contraindications for its use, since the main substance, ketalorak, has a number of properties that can do more harm than good in a given situation.

Individual intolerance to the main active ingredient.
Problems with the gastrointestinal tract.
Kidney or liver failure.
Pregnancy, as well as the period of breastfeeding.
Age up to 16 years.
Stroke, as well as various blood diseases.
Preoperative period due to the high likelihood of bleeding.
Asthma.

In addition to the listed contraindications, it is worth remembering that this drug should be used only after consultation with your doctor, since there is some possibility that Ketanov may not help. Also, this medicine is not recommended, or rather, it is prohibited to treat chronic pain, since the nature and origin are completely different, and they require a different approach to treatment (or alleviation of the patient’s condition).

When is the drug prescribed?

The composition of the ampoules allows for intravenous injections in the presence of the following indications:

Rheumatoid arthritis, which affects the small and large joints of the extremities.
Osteoarthritis affecting cartilage tissue.
Psoriatic and gouty arthritis.
Ankylosing spondylitis, which causes limited mobility of the spine. This is due to the fusion of intervertebral joints and the occurrence of inflammation in them.
For various pain syndromes - neuralgia, tendonitis, joint pain, ossalgia, bursitis, radiculitis, adnexitis, back pain and toothache.
Prescribed as an analgesic during the period of postoperative pain and syndrome that occurs along with inflammation.
Injections help cope with pain associated with oncology and tumors.
Ketonal injections are prescribed by doctors to women during painful menstruation and during childbirth.

Interaction between Ketanov and alcoholic beverages

Alcohol is one of the most powerful toxic substances. It disrupts the functioning of organs in the body. Alcohol poses the greatest danger to the liver as a kind of filter for the body. Ketanov also causes harm to liver functions. The ability of the two substances to interact increases the amount of toxins available for processing.

Alcoholic drinks will cancel the therapeutic effects of the drug. Exceeding the permissible dosage increases the risk of adverse reactions of the drug. The general consumption of alcohol with Ketanov leads to injury to the gastric mucosa. As a result, painful ulcerative lesions form.

Alcohol significantly enhances the analgesic effect of the drug. Under the influence of the medicine, the patient does not feel increasing pain and does not seek medical help. Such actions lead to the development of serious pathologies. If you mix alcohol with Ketanov, consumption causes pronounced side effects prescribed by the manufacturer in the instructions:

nausea and vomiting;
ulcerative manifestations in the gastrointestinal tract;
liver pathologies;
pain in the lower back and stomach;
diseases of the urinary tract and organs;
visual-auditory impairment, tinnitus;
disruptions in the functioning of the heart and blood vessels, in the functions of the respiratory tract;
dysfunction of the nervous system, expressed in the form of increased activity, headaches and neck pain, depressive tendencies and fatigue.

Negative consequences are expressed by visual defects of the skin. Among the side effects that occur is the formation of stomach ulcers. Patients with problems in the gastrointestinal tract are prohibited from using Ketanov. It is not recommended to combine the medicine with strong drinks.