Furazolidone is the first remedy for stomach infections in children

Children under 4 years of age are especially sensitive to intestinal infections because they have not yet developed a strong immune system. The child's body cannot fully produce antibodies to microbes, which leads to intoxication of the entire digestive system. To eliminate the infection, use Furazolidone. This effective, but still toxic drug is given to children strictly as prescribed by the doctor.

Directions for use and dosage

Furazolidone is intended for oral use. The tablet must be swallowed whole, without chewing first, and washed down with a sufficient amount of water. The recommended course of treatment and daily doses depend on the nature and stage of the pathological process:

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Furazolidone for children

In pediatrics, the drug is prescribed in the form of granules for the preparation of a suspension for parasitic diseases, intestinal infections, wounds and burns. The calculation of the daily dosage for children is carried out by a pediatrician, taking into account the age and weight of the small patient:

• from 1 to 12 months: 10 mg per 1 kg of weight for 3 days, then take a three-day break and repeat treatment;
• from 1 year to 8 years: the maximum dosage is 0.15 g, the course of treatment is no more than 10 days.
• children over 8 years of age: the daily dose is 5 mg per 1 kg, divided into 3-4 doses.

It is recommended to first dilute the drug in the form of granules for preparing a suspension with boiled water and mix thoroughly until the sediment is completely dissolved. Then take orally according to the instructions. Furazolidone tablets are contraindicated for children under 3 years of age.

For cystitis

Furazolidone destroys pathogenic intestinal flora, which provoked an exacerbation of inflammatory processes in the genitourinary system and bladder. To eliminate urogenital infections, you need to choose the right daily dosage:

• children from 1 year: 10 mg per 1 kg of weight, divide the received dose into 3 doses. The course of treatment is 3 days, after which a three-day break is taken, and treatment is resumed.
• adults: 2 tablets. 4 doses per day, the course of treatment varies from 3 to 7 days.

Furazolidone for diarrhea

For diarrhea, Furazolidone tablets are prescribed after meals and are recommended to be taken with plenty of water. The course of treatment should not exceed 10 days, but positive dynamics are noticeable already on days 3–5 of home therapy. Daily doses depend on the patient's age:

• Furazolidone for children over 1 year of age: 10 mg per 1 kg of child’s body weight, divided into 3 doses;
• patients over 5 years: 0.5–1 table. four times a day;
• adults: 2–3 tablets. three times a day.

What can replace the product?

If a child develops an allergic reaction while taking Furazolidone, or the drug is found to be ineffective, the pediatrician may prescribe another drug with a similar therapeutic effect.

Furazolidone analogues - table

Medications in the photo

Nevigramon is not more effective than Furazolidone, but is 75 times more expensive

Stopdiar in the form of a suspension is suitable for babies

Furadonin often “works” against urological infections in children

There are different forms of enterofuril, including a children's suspension

Indications and methods of administration for children

Before giving Furazolidone at the first signs of illness, it is necessary to conduct an examination and consult with a pediatrician. A child’s complaints of abdominal pain do not always mean an acute intestinal infection and require immediate medical treatment. The drug is prescribed only if the doctor confirms the infectious nature of the disorder.

The most common ones may be:

• Various forms of dysentery (Shigella infection).
• Paratyphoid fever (spreads salmonella).
• Food poisoning.
• Giardiasis.
• Rod or coccal infections.

During an acute gastrointestinal disorder, a child may develop water or electrolyte imbalance due to frequent vomiting and diarrhea. In addition to antibacterial treatment, it is necessary to carry out rehydration (replenish fluid volume) and restore the intestinal microflora. There are special medications for this.

The use of nitrofurans to treat bactericidal infestations of a child is possible only from the age of twelve months. Prescribing them to children under one year of age is strictly prohibited in any of the available forms.

Until the child is 5 years old, the only possible way to treat with Furazolidone is to use a suspension. It is obtained from granulated powder, diluted with warm boiled water to the required volume. For children over five years of age (with rare exceptions, treatment at 3 years of age is allowed) the drug can be given in tablets.

Dosing Features

The daily dosage is determined by the child’s weight. The calculation should be 10 mg per 1 kg of body weight. The resulting figure should be divided into three or four doses. The medicine is given strictly after meals at regular intervals. If these are tablets, wash them down with plenty of water. The duration of treatment can be from 3 to 5 days. The maximum course of therapy is limited to ten days.

Illustrative examples of how to properly give Furazolidone to children:

• The sick child is 2–3 years old and weighs almost 12 kilograms. Use only suspension. The daily dose of the drug will be 10 ml * 12 kg = 120 ml. Divide into 3-4 equal parts and calculate a single dose. It turns out that the baby needs to be given 30 or 40 ml of Furazolidone once a day, respectively.
• It is expected to treat a child over six years old, whose weight is 20 kg. Apply the tablets. Calculate the daily volume of the drug according to the scheme - 10 mg * 20 kg = 200 mg. Similarly, divide into an equal number of doses and get 50 mg, which is equal to 1 tablet.

The duration of therapy depends on the diagnosis and severity of the disease.

Release form

The medication is produced in tablets that have a yellow or yellow-green color, a flat-lindrical shape and a chamfer. Each tablet for abdominal pain is packaged in a contour-free packaging of ten pieces and placed in a cardboard pack of one or ten packages, supplied with a leaflet with instructions. Tablets can also be packaged in blister packs and placed in a cardboard pack of one, two, five, fifty or one hundred packages, accompanied by folding instructions.

Each tablet contains fifty milligrams of the active substance furazolidone, as well as a certain amount of excipients lactose monohydrate, colloidal anhydrous silica, calcium stearate, potato starch.

Does Furazolidone help with diarrhea?

It is not recommended to use the medication together with antidepressants, since simultaneous use causes an increase in blood pressure. When taken simultaneously with alcohol, teturam-like reactions develop, which can lead to coma. The drug enhances the effect of tetracycline and aminoglycosides (kanamycin, gentamicin). Furazolidone allows you to fight the following ailments:

• typhoid fever;
• dysentery;
• paratyphoid fever;
• giardiasis;
• food poisoning;
• salmonellosis.

In most cases, the drug is not addictive. Indications for use:

• disorder due to infection of various parts of the intestine. The drug quickly neutralizes loose stools. In this case, treatment is supplemented with sorbents;
• prevention against lamblia.

1. Nausea and vomiting.
2. Decreased appetite.
3. Allergic reactions manifest themselves in the form of rashes and itching.
4. With long-term use - polyneuritis.
5. Increasing intensity of urine color with a change in color: from pink to dark brown.
6. Palpitations, sweating, increased body temperature, feeling hot and anxious - after drinking alcohol during treatment.

To avoid side effects, it is recommended to take Furazolidone before meals with a sufficient amount of liquid. If serious side effects occur, call a medical team at home.

How safe is the drug for children?

Safety is the determining criterion for choosing a drug for the treatment of gastrointestinal disorders in children in the first months of life.

The high effectiveness of Furazolidone is combined with a low likelihood of side effects. Complications are associated with overdose and taking the drug in the presence of contraindications.

Side effects

By giving Furazolidone to the baby, bypassing the doctor’s recommendations, parents increase the risk of developing the following side effects:

• nausea and vomiting;
• decreased appetite;
• diarrhea;
• dizziness and headache;
• weakness and decreased activity;
• drowsiness;
• irritability;
• local allergic reactions - rash and itching of the skin.

If mild side effects occur, you can divide the daily dose of the drug into 5-6 doses. It must be remembered that Furazolidone is toxic, and therefore must be taken after meals. It is better to drink the medicine together with sorbents: activated carbon, Smecta, Sorbex. To prevent allergies, the baby is given antihistamines.

Overdose

Furazolidone, used to eliminate intoxication, if used incorrectly, leads to severe drug poisoning. In such cases, a deterioration in the course of the underlying pathology is most often noted, but the following also develops:

• shortness of breath and cough;
• convulsions;
• pain in the epigastric region;
• hyperthermia;
• liver intoxication;
• polyneuritis;
• excess and decrease in hemoglobin in the blood, which is especially dangerous for a one-year-old baby.

If signs of overdose occur, you should immediately consult a doctor. Due to the lack of an antidote to Furazolidone, these symptoms are eliminated by gastric lavage, taking sorbents and laxatives. In case of severe drug poisoning, restoration of water and electrolyte balance is indicated.

Contraindications

Furazolidone is a toxic drug and can worsen the course of some somatic diseases.

It is inadmissible to take the medicine if there are the following contraindications:

• patient hypersensitivity to the components of the drug;
• severe pathologies of the liver and kidneys;
• neurological disorders;
• lactase deficiency and lack of glucose-6-phosphate dehydrogenase;
• up to one year of age.

Interaction with other drugs

When giving Furazolidone to children, you need to remember its ability to react with certain drugs. To avoid sudden jumps in blood pressure, this medication is not prescribed with antidepressants and vasoconstrictors. The combination of Furazolidone with the antibiotics Ristomycin and Chloramphenicol provokes circulatory problems.

The antimicrobial properties of Furazolidone increase if it is taken with aminoglycosides, tetracyclines and drugs that acidify urine. In order not to disrupt the treatment process, you should stop using these medications for 2 weeks after your last medication intake, unless otherwise directed by your doctor.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Furazolidone is an antimicrobial agent derived from nitrofuran. Salmonella, Shigella, Campylobacter, as well as protozoa (Gardia, Trichomonas) and Vibrio cholerae are highly sensitive to it. Depending on the concentration, it has a bactericidal or bacteriostatic effect.

The mechanism of action is the blockade of many enzyme systems of the microorganism. Nitrofurans disrupt cellular respiration, suppress the Krebs cycle and block the biosynthesis of nucleic acids. As a result, the shell of microorganisms or their cytoplasmic membrane is destroyed. When the drug acts, destroyed microbial cells release less toxins. Unlike other antimicrobial agents, they activate the immune system.

Acts on strains resistant to some antibiotics. Does not affect anaerobes and Pseudomonas aeruginosa. Resistance of microorganisms to the drug occurs rarely.

What is Furazolidone used for? Since it is poorly absorbed from the gastrointestinal tract and high concentrations are created in the intestine, it is used for intestinal infections of bacterial and protozoal etiology. Unlike Furadonin, it is characterized by low toxicity.

Pharmacokinetics

Well absorbed when taken orally. Distributed in tissues and liquids. In the cerebrospinal fluid during meningitis, the same concentrations are created as in the plasma; therapeutic concentrations are also achieved in the intestinal lumen. Intensively metabolized in the liver to an inactive metabolite. Excreted by the kidneys (up to 65%), small amounts are determined in feces,

What is the use of the drug based on?

The widespread use of Furazolidone in the treatment of bacterial infections is based on the absence of rapid adaptation of pathogenic microorganisms to its main ingredient. This allows the drug to be used in the treatment of patients with chronic diseases during their relapses. Furazolidone is used in the treatment of digestive disorders, when antibiotic therapy is extremely undesirable due to the development of complications, for example, dysbiosis.

Antimicrobial action

The active substance Furazolidone has the ability to disrupt the processes of cellular respiration of pathogenic microbes. After the drug penetrates the gastrointestinal tract, it is absorbed by the mucous membranes and enters first into the systemic bloodstream, and then transferred to the inflammatory focus. The mechanism of the antimicrobial action of Furazolidone lies in its ability to:

• suppress the metabolic breakdown of tricarboxylic acid;
• destroy cytoplasmic membranes and outer shells of microorganisms.

Violation of the integrity of bacterial cells causes inhibition of growth and suppression of the active reproduction of bacteria of pathogenic and opportunistic microflora.

Often, patients with pyelonephritis, glomerulonephritis, and intestinal infections develop symptoms of general intoxication. They are provoked by toxins that enter the bloodstream - waste products of microbes. The use of Furazolidone prevents the development of events in such a negative scenario, since the number of bacteria in the gastrointestinal tract, bladder, kidneys and urethra is gradually reduced.

Boosting immunity

The undoubted advantage of Furazolidone is the ability to increase the activity of white blood cells. Under the influence of the drug, the ability of leukocytes increases:

• destroy infectious pathogens;
• prevent their growth and reproduction.

The drug has the ability to quickly reduce the severity of inflammation, from which Furazolidone tablets are taken to increase the body's resistance to infectious agents, as well as strengthen general immunity.

Recommendation: “Unlike antibacterial drugs, Furazolidone does not destroy beneficial intestinal microflora, but takes an active part in its preservation.”

The first signs of an overdose

Overdose of Furazolidone occurs for three main reasons:

• incorrect selection of the required amount of active substance;
• pathologies of the urinary system, due to which the drug is retained in the body;
• independent adjustment of the duration of treatment.

As a result of an overdose, a person experiences the following symptoms:

1. Hepatotoxicity is a disturbance in the structure and functionality of the liver, which is accompanied by a feeling of heaviness in the right hypochondrium, vomiting with bile, and a change in the color of the stool to green.
2. Polyneuritis is multiple lesions of nerve tissue, which is manifested by decreased muscle sensitivity, decreased muscle strength, and impaired nutrition of muscle tissue.
3. Hematotoxicity is a selective disruption of the functions of blood cells and its cellular composition.

There is no specific treatment for overdose.

Therapy is carried out symptomatically, and the following is performed:

• gastric lavage with drug withdrawal;
• prescription of electrolyte solutions;
• use of enterosorbents.

Additionally, B vitamins are prescribed to restore the functions of nerve tissue and antihistamines to reduce the intensity of allergic reactions.

If a person has a severe overdose due to impaired kidney function, he may be prescribed hemodialysis.

With severe damage to the nervous tissue and liver, there is a possibility of incomplete restoration of their normal functioning after the end of the course of treatment with the drug.

Contraindications, possible side effects and overdose

Furazolidone is contraindicated in:

• hypersensitivity to nitrofurans;
• chronic renal failure (end stage);
• diseases of the nervous system;
• deficiency of glucose-6-phosphate dehydrogenase.

Furazolidone has minimal toxicity, so it can be safely used in the dosage prescribed by the pediatrician for the treatment of children over one year of age.

In some cases, taking the drug can lead to the development of undesirable consequences:

• allergic manifestations (rash, itching, redness, angioedema);
• problems with the gastrointestinal tract - loss of appetite, nausea, vomiting;
• neuritis (with long-term use).

In case of overdose, you must call an ambulance

In case of overdose, the following complications are possible:

• hemolytic anemia and methemoglobinemia;
• acute toxic hepatitis (damage to liver cells);
• dysfunction of blood cells or its cellular composition;
• polyneuritis.

In case of overdose, you must call an ambulance as soon as possible. Before the doctor arrives, it is recommended to give the baby warm water to drink.

How to help a child with food poisoning (Dr. Komarovsky) - video

Furazolidone analogues for diarrhea

If it is clear that diarrhea is caused by infections, one of the possible analogues may be the antibiotic Fthalazol, which belongs to the group of sulfonamides. It is somewhat cheaper than Furazolidone and belongs to a different group of antibiotics, which means it may be suitable if you are allergic to Furazolidone. Sulgin belongs to the same group as Phthalazol.

Another analogue is Enterofuril, which is part of the same drug group as Furazolidone, but has fewer adverse reactions and is suitable for treating children under one year of age. Available in the form of tablets and suspensions, which facilitates dosing of the drug for treating a child. The price is higher than that of analogues.

Other antibiotics with similar indications for use:

• Levomycetin (may be effective where Furazolidone is powerless, but has a wider range of contraindications and side effects).
• Amoxicillin (broad spectrum of action with fewer contraindications).

If the cause of diarrhea is not clear, you should use enterosorbents, for example, activated carbon or Enterosgel and consult a doctor.

Furazolidone is an antibiotic active against intestinal pathogens. This drug should only be used for diarrhea if it is clear that it is caused by bacteria susceptible to the antibiotic.

It is important to follow the regimen and dosage of the drug, take into account compatibility with other medications and existing contraindications

Anti-diarrhea tablets Furazolidone is an effective medicine for loose stools and has good antibacterial characteristics. This property allows you to effectively remove infections from the body and improve the digestion process.

Description of the drug Furazolidone

Furazolidone is an active antimicrobial and antiprotozoal drug from the group of nitrofurans, antibacterial agents that can suppress the process of cellular respiration of pathogenic microorganisms and protozoan parasites, as well as the formation of nucleic acids.

One of the important advantages of Furazolidone is that pathogenic bacteria are not able to form strains resistant to the drug, and this property determines its high effectiveness.

The effectiveness of Furazolidone in destroying microbes is much higher than that of Furacilin, Furadonin, Furagin, and its toxicity is approximately five times less.

Furazolidone in tablets is approved for children from five years of age.
Furazolidone exhibits the greatest activity against gram-positive streptococcus and staphylococcus, gram-negative bacilli of the species Proteus, Shigella, Escherichia, Klebsiella, Enterobacter, as well as against protozoa - Giardia, Trichomonas. The pathogens of paratyphoid fever, dysentery, and typhoid fever react especially strongly to the antibacterial effect of the drug.

As a result of the activity of Furazolidone, harmful microbes release fewer toxins, so improvement in the patient’s condition often occurs very early - even before the pathogenic microflora is completely suppressed. Moreover, the drug has the rare property of stimulating the body’s protective functions and the ability of leukocytes to kill foreign microorganisms.

The drug is quickly absorbed and excreted by the kidneys and intestines.

Release forms

Furazolidone is available in two pharmaceutical forms:

• Yellow flat-cylindrical tablets with a bevel, 0.05 g each. The active ingredient is furazolidone, additional substances: potato starch, lactose monohydrate, polysorbate, calcium stearate, sugar, colloidal silicon dioxide. Not used to treat children under 5 years of age.
• Yellow and greenish-yellow granules with a characteristic odor, used in pediatrics for the preparation of a suspension. Packaging 50 g in glass bottles with a volume of 150 ml. Additionally, a plastic measuring cup is included. The granule suspension is approved for use in children from 12 months.

The concentration of the active substance in granules is lower than in tablets.

Instructions for use for diarrhea

Furazolidone has instructions for use in adults for diarrhea. Each form of the disease has its own dosage. The therapeutic plan should be approved by the attending physician. Self-medication can lead to dangerous consequences and deterioration of health. After completing the full recovery course, tests are taken. This way you will determine the current state.

For adults, the manufacturer of the drug recommends taking 2 tablets per day at equal intervals. The hours of taking the substance should not be changed. The drug is actively used to eliminate loose stools in children. Read the instructions carefully and follow the dosage to avoid a large number of side effects. The concentration of the compound has the following gradation:

• for newborns and babies under 1 year of age, taking the substance is prohibited;
• up to 3 years of age, ½ tablet is given every 8 hours until complete recovery;
• over 12 years old - take 1 tablet three times a day;
• child over 12 years old – 1.5 tablets every 6 hours. If an allergic reaction occurs, drug treatment is stopped.

Furzalidone anti-diarrhea tablets are taken orally. If an adult falls ill with dysentery, a course of treatment of 7-10 days is prescribed (1-3 tablets every 6 hours). The dosage is selected by a pediatrician or gastroenterologist. It is prohibited to exceed the concentration of 10 mg of the drug per 1 kg of baby’s weight. To eliminate Giardia, the following regimen is used: 2 tablets every 6 hours (for adults).

In case of overdose, drug-induced hepatitis may develop, and in case of chronic overdose, polyneuritis may develop. At the first signs of intoxication, it is necessary to perform gastric lavage. After the procedure, the sorbent is taken. Sometimes the doctor prescribes a saline laxative. To promptly restore the patient’s body, vitamin therapy is necessary - B vitamins are used through intramuscular or intravenous administration.

Avoid drinking alcoholic, carbonated drinks and eating fatty foods 7 days before and after treatment with the substance.

Pay attention to tips that will minimize troubles:

• if no improvement is observed after a week of therapy, stop recovery;
• in case of metabolic disorders, treatment with the drug is carried out under the strict supervision of a doctor;
• in some cases, the medication may have the opposite effect in the form of acute diarrhea.

It is recommended to store the medicine in dark places out of reach of children. When exposed to moisture and high temperatures, the chemical loses its beneficial properties. The drug is sold in pharmacies without a prescription. Self-medication at home is prohibited! After the expiration date (36 months), the tablets are discarded.

Analogs

In case of side effects or if there are medical contraindications, Furazolidone is not prescribed. Analogues of the drug and their brief characteristics:

1. Nifuroxazide. Yellow tablets have a bactericidal and antibacterial effect and are recommended for use in adult patients. Children are prescribed a sweet suspension with fruit flavor. The drug helps well with diarrhea of ​​various origins.
2. Rifaximin. A medicine with an identical principle of action in the body. It has 2 dosage forms - tablets and suspension for oral use. It is important to avoid cases of overdose.
3. Imipenem. This is a bactericidal, antibacterial, antimicrobial agent recommended for infections of the genitourinary system, abdominal organs, and respiratory tract.
4. Azithromycin. These are tablets, capsules and powder with an antibacterial effect. This is a semi-synthetic antibiotic, effective for the extermination of gram-positive, gram-negative bacteria, protozoa, strains.
5. Amikacin. The medication is produced only in the form of a white powder for the preparation of an injection solution (intramuscular, intravenous). There is no tablet form of Amikacin.
6. Ciprofloxacin. These are ear and eye drops, tablets, infusion solution with a pronounced bactericidal effect, and is an early fluoroquinolone. The drug is an antibiotic and is evenly distributed in tissues.

Analogues of Furazolidone, price in pharmacies

If necessary, you can replace Furazolidone with an analogue for therapeutic action - these are the following drugs:

1. Nifuroxazide,
2. Entprofuril,
3. Rifaximin,
4. Imipenem,
5. Azithromycin,
6. Fluoroquinolone,

When choosing analogues, it is important to understand that the instructions for use of Furazolidone, price and reviews do not apply to drugs with similar effects. It is important to consult a doctor and not change the drug yourself

Store at room temperature in a dry place out of reach of children. Shelf life: 3 years.

Sale in pharmacies without a prescription.

Cystitis is an unpleasant disease in which inflammation of the mucous membrane of the bladder occurs.

It has its own characteristic features. You should consult a doctor if you have symptoms such as:

• frequent painful urination;
• lower abdominal pain;
• elevated temperature.

The disease is infectious in nature. The causative agent of the disease enters the bladder through the bloodstream or directly from the source of infection. Women often get sick, since the characteristics of their body favor the infection to enter the urethra, and through it to the bladder.

Pathogenic microorganisms enter there from the vagina or rectum. Despite the fact that cystitis occurs more often in women, men can also suffer from it; cystitis in children is dangerous. The cause of inflammation of the mucous membrane of the bladder can be sexually transmitted diseases, dysbacteriosis, and foci of infection in the body.

There are many medications available to treat cystitis. Due to the modern abundance of drugs, it is difficult to choose just one; their names are similar. Patients are often interested in whether Furadonin and Furazolidone are the same drug or not?

You need to compare them to understand the difference. In pharmacies you can find many medications for cystitis, they all have their own properties, contraindications and side effects.

Scope of application of the pharmacological drug

The powerful antimicrobial and antibacterial properties of Furazolidone provide its wide therapeutic range of use.
Since the drug in some cases acts as an immunomodulator, it is used in the treatment of diseases caused by pathogenic fungi. Furazolidone exhibits the greatest activity against gram-negative anaerobic microorganisms, and aerobes are resistant to the drug. The therapeutic effect of tablets is directly dependent on the concentration of the active substance in the systemic circulation:

• the use of high doses leads to the destruction of bacterial cells;
• a small amount of the drug causes inhibition of the growth and reproduction of infectious pathogens.

Therefore, single and daily doses, as well as the duration of the course of treatment, are determined by a urologist or gastroenterologist. When prescribing, it is based on the results of laboratory tests, taking into account the patient’s age and history of diseases.

Furazolidone is able to destroy pathogens of pyelonephritis

Taking pills for cystitis and pyelonephritis

Furazolidone is often prescribed by urologists to patients who have been diagnosed with acute cystitis or pyelonephritis. Almost all pathogens of these pathologies are sensitive to the active substance of the drug. But there are also application features based on the pharmacokinetics of the drug. Metabolism of the main and auxiliary ingredients of Furazolidone occurs in liver cells (hepatocytes). Under the action of enzymes, large conglomerates are formed, which are excreted:

• with bile acids;
• every time you empty your bladder.

Most of the drug leaves the body with feces, so its significant concentration is found in the intestines. When prescribing Furazolidone for pyelonephritis or cystitis, the urologist takes this feature into account and includes additional antibacterial drugs in the therapeutic regimen.

Use for intestinal infections

The main symptoms of gastrointestinal infections include vomiting, diarrhea, and fever. Such diseases are especially dangerous for young children, as they quickly provoke dehydration and loss of important mineral compounds. Furazolidone is prescribed by gastroenterologists when diagnosing the following pathologies in adults and children:

• rotavirus infection;
• amoebic dysentery;
• salmonellosis;
• cholera;
• giardiasis;
• typhoid fever;
• intestinal flu.

The drug actively destroys infectious agents, a common cause of which they enter the body is dirty hands and unwashed fruits and vegetables. It is not advisable to use Furazolidone for diarrhea of ​​unknown origin. It can occur in humans against the background of diseases of the gastrointestinal tract not associated with infection by microbes.

Advice: “When treating intestinal infections, you need to take Furazolidone tablets with plenty of clean water. During the absorption of the drug by the mucous membranes, they become excessively dry, which negatively affects the background of general dehydration of the body.”

Furazolidone quickly and effectively eliminates the symptoms of intestinal infections

Application in the treatment of children

The drug is not used in the treatment of children under one year of age. What are the indications of Furazolidone for babies older than one year:

• acute, chronic intestinal infections;
• inflammation of the mucous membrane of the bladder and urethra;
• burns.

The yellow tablets can be swallowed whole or dissolved in plenty of water. The first option is preferable due to the bitter taste of the tablets. But consuming a solution of the drug will allow the active substance to quickly exhibit a therapeutic effect. When treating children, it is strictly prohibited:

• combine the use of Furazolidone with medications that are not included in the therapeutic regimen by the doctor. This can cause unwanted chemical reactions and unpredictable complications;
• exceed the dosages recommended by a pediatric urologist or gastroenterologist, the frequency of tablets taken and the duration of the course of treatment in the hope of a speedy recovery.

If a day after taking Furazolidone the child’s health condition has not improved, then the doctor should be informed about this. He will adjust dosages, replace medications, or supplement the therapeutic regimen with new drugs.

Combination with other drugs

Before taking a medication, it is recommended that you review the list of medications that interact with this drug to prevent excess stress on the body.

Interaction of Furazolidone with other drugs and substances:

• combination with products containing ethylene increases susceptibility to alcohol, which leads to a hyperreaction, so the drug can be prescribed in the treatment of alcoholism;
• antidepressants, MAO inhibitors, Phenylephrine, Tyramine, Ephedrine, Amphetamine can cause an increase in blood pressure while taking Furazolidone;
• the inhibition of hematopoietic processes increases when combined with Chloramphenicol and Ristomycin;
• alkaline-based drugs reduce the effect of Furazolidone;
• acid-based preparations activate the effectiveness of the active substance;
• antibiotics of the aminoglycoside and tetracycline groups enhance the antimicrobial effect.

Additionally, it is recommended to avoid foods containing tyramine, which act as MAO inhibitors. This is cheese, black coffee, cream, beans, pickled herring.

To enhance the therapeutic effect, the medicine can be combined with enterosorbents (Enterosgel, activated carbon, Smecta). They help bind toxins released by pathogenic microorganisms, thereby alleviating the patient’s condition during general intoxication.

Drug interactions

Furazolidone should not be combined with alcohol-containing drugs, since the risk of toxic effects on the liver increases (disulfiram-like reactions develop) and depression of the nervous system occurs. Other information about drug interactions is described in the instructions for use:

1. The simultaneous use of the medication with antacids, magnesium, aluminum and iron preparations is prohibited, since the absorption of Furazolidone and its therapeutic effect are reduced.
2. In combination with Tetracycline and aminoglycosides, the antimicrobial effect of both medications is enhanced, so additional adjustment of daily dosages is required.
3. Antidepressants, MAO inhibitors, Phenylephrine, Ephedrine, Tyramine, Amphetamine contribute to an increase in blood pressure during the use of Furazolidone.
4. When used simultaneously with Chloramphenicol and Ristomycin, the functioning of the hematopoietic organs is disrupted (blood clotting is reduced).

Instructions for use of the drug

The method of administration and dosage of Furazolidone may vary depending on age and disease. You can read about how to take Furazolidone in the instructions for use. It is recommended to adhere to the following regimens and doses for treatment of the adult population:

1. The tablets are taken orally after meals with water.
2. For all kinds of toxic infections, bacillary dysentery, and paratyphoid fever, adults should take 100-150 milligrams four times a day. The course of therapy is 5-10 days. The duration of treatment can be adjusted depending on the severity of the disease and its nature. In some cases, the drug is prescribed at the same dose in several 3-6-day cycles with breaks of three or four days.

1. Furazolidone for giardiasis is prescribed at a dose of 100 milligrams four times a day. The duration of medication is determined by the doctor individually depending on the severity of the disease and the patient’s condition. The maximum daily dose for adults should not exceed 800 milligrams, and the maximum single dosage is 200 mg.
2. For the treatment of Trichomonas urethritis, 100 milligrams are prescribed four times a day for three days.

Furazolidone during pregnancy

Research has revealed that this medication has a negative effect on the fetus, so the use of this medication during pregnancy is strictly contraindicated.

Since the active component can pass into breast milk, Furazolidone is not prescribed during lactation. If there is a need for treatment during lactation, breastfeeding must be interrupted for the duration of therapy.

How to take Furazolidone for children?

Furazolidone can only be prescribed to a child by the attending physician. If you purchased Furazolidone for children, the instructions state that the medication must be taken in accordance with the following regimen and doses:

Anti-worm suppositories for children and adults

1. When treating dysentery, toxic infections and paratyphoid fever, the dose for a child is calculated based on weight. It is equal to 10 milligrams per kg. This daily dose must be divided into 4 doses. The duration of treatment is no more than a week.
2. For giardiasis, children are prescribed 10 milligrams per kg. The daily dose is divided into several doses. The duration of the course is determined individually.

How does overdose and side effects manifest?

Instructions for children and adults prescribe symptoms of a drug overdose.
Among them it is worth noting:

• manifestations of neurotoxicity;
• signs of hematotoxicity;
• acute forms of toxic hepatitis.

For such situations, the instructions for use for children and adults provide for special treatment in the form of discontinuation of Furazolidone. You should also drink a lot of water and possibly use symptomatic therapy. Patients are often prescribed antihistamines and vitamin B in tablets.

The instructions for use for children clearly state the symptoms of the side effects of the medicine on the body.

Among them are:

• possible neuritis;
• manifestations of skin rash;
• itching sensations;
• swelling;
• allergic reactions;
• nausea with bouts of vomiting;
• loss of appetite.

Indications for use of Furazolidone:

1. It is not recommended to combine medication with alcohol. Such a union has a negative impact on the health of patients.
2. An increased dosage of the drug also negatively affects the healthy intestinal microflora.

Many patients often ask: “Is furazolidone an antibiotic?” Indeed, the release form of the drug classifies it as an antibiotic.

Therefore, the course of its administration is very limited, otherwise the beneficial microflora of a sick person may be seriously affected. Now it’s clear whether it’s an antibiotic or not.

Instructions for use of Furazolidone

The dose for adults for paratyphoid fever, dysentery and food poisoning is 0.1 g per day 4 times a day for 5–10 days. Single dose - 0.2 g, daily dose - 0.8 g.

For giardiasis - 0.1 g 4 times a day for up to 7 days, after a week the same course is repeated.

For trichomonas urethritis - 0.1 g 4 times for 3 days.

For trichomonas colpitis, the dosage and frequency of administration are the same and in parallel, a powder containing furazolidone and milk sugar is injected into the vagina, and suppositories containing 4-5 mg of furazolidone are administered into the rectum.

For the treatment of burns locally in the form of bandages with a solution of the drug (1:25000).

Instructions for use for children

For children, the dose is calculated per kg of body weight. It is: one-time - 0.0025 g per kg, and daily 0.01 g per kg, distributed over 3-4 doses. The course of treatment is 5-7 days.

Application in veterinary medicine

The veterinary drug is a yellow powder, insoluble in water.

The drug is used for salmonellosis, coccidiosis, colibacillosis, enteritis, balantidiasis in animals and birds. You can also use a pharmaceutical drug in tablets (one tablet contains 50 mg).

The dosage for these diseases is the same for chickens, turkey poults and broilers - the drug is added to the feed at the rate of 3 mg per head 2 times a day, treatment is carried out for 8 days. If necessary, the course of treatment is repeated, but after a break of 10 days. As a preventative measure, young animals up to 10 days of age are given 2 mg per head once a day.

An overdose is unacceptable, since the bird becomes drowsy, lethargic and may die. How to feed to chickens? Better with food. Another option is to dissolve it in water and give it as a drink. But you need to know that the drug does not dissolve well and loses its properties when exposed to sunlight.

Admission rules

During treatment you should adhere to certain rules:

• While taking the pills and 3 days after the end of the course, you should not take alcohol, as taking them together causes: nausea, cough, redness of the skin, fever, chills, a sharp drop in blood pressure, up to the appearance of coma; What you can drink if you have intestinal disorders can be read here.
• It is forbidden to eat foods containing tyramine (cheeses, smoked meats, coffee, chocolate, pickled fish, red wine, cream, beans and others. Furazolidone is an MAO inhibitor and when consuming such products, blood pressure will rise sharply and a headache will occur;
• the medicine cannot be combined with antidepressants, MAO inhibitors, since ephedrine, amphetamine, phenylephrine, tyramine cause a sharp increase in blood pressure;
• During the course of treatment, it is recommended to additionally take vitamins from group “B” due to the risk of neuritis;
• It is forbidden to exceed the recommended dosage or if you miss a pill, take a double dose - damage to the liver, kidneys, hematopoietic organs and nervous system is possible;
• Long-term use of the drug is permitted only under the supervision of the attending physician.

Furazolidone dosages for various diseases

The drug is used mainly for intestinal infections; it is not used to treat urinary tract infections.

Let's consider standard dosage regimens for various diseases:

• for dysentery, salmonellosis and typhoid fever, a dose of 0.15 g is prescribed for a week. frequency 4 times a day;
• in case of food poisoning or intestinal flu, take 0.1 g for 5 days. 4 times a day;
• for giardiasis, 0.15 g is prescribed. 4 times a day, course duration – 10 days;
• for trichomonas colpitis and urethritis, 0.1 g is prescribed. the drug 4 times a day for 14 days;
• For the treatment of shigellosis, treatment with 0.15 g is prescribed. frequency 4 times a day for a week;

Dosage for children:

The medicine for diarrhea and giardiasis is quite loyally prescribed to children over the age of one year; contraindications for Furazolidone tablets include children under 1 month of age, for granules and powders – less than 1 year

Be sure to use caution when taking this product to your child.

For children over 3 years of age, Furazolidone is prescribed based on weight, the dosage is calculated by the attending physician, under whose supervision the treatment is carried out. Due to the high frequency of side effects from taking pills, as well as the possibility of nausea or vomiting, self-medication is not recommended.

Reception during pregnancy and lactation

During pregnancy, the medicine is not prescribed due to the fact that Furazolidone has a wide spectrum against microorganisms and a high incidence of side effects.

• liver;
• kidneys;
• central nervous system (hepatotoxicity, hematotoxicity and neurotoxicity).

Active ingredients and principle of action of the drug

The main active ingredient of the drug is furazolidone, a derivative of nitrofurans. It inhibits monoamine oxidase (MAO), which inhibits metabolic processes in pathogenic microorganisms.

The effect of use is observed 2-5 days after the start of treatment, but general relief of the condition is observed much earlier.

When interacting with pathogenic microorganisms, furazolidone inhibits cellular metabolic processes, thereby inhibiting the growth of the number of pathogenic bacteria.

Active microorganisms begin to release fewer toxins, which is why a person’s condition improves long before the pathogenic microflora in the body is destroyed.

The drug primarily acts in the intestines. The remedy for diarrhea is poorly absorbed in other organs of the gastrointestinal tract, and therefore enters the blood in very small quantities.

Pregnant and lactating women are not recommended to drink Furazolidone to treat diarrhea, since the absence of its negative effect on the child’s body has not been reliably proven.

pharmachologic effect

The drug Furazolidone is a derivative of 5-nitrofurforol of synthetic origin. Its maximum effectiveness is observed in the treatment of inflammatory diseases caused by gram-negative bacilli. Gram-positive cocci, protozoan microorganisms and fungi are less sensitive to this drug. Anaerobic pathogens are not sensitive to the drug.

The drug has a pharmacological effect that depends largely on the dose. At a lower dosage, furazolin will have a bactericidal effect, while at a higher dosage it will have a bactericidal effect. The mechanism of action of the drug is explained by the fact that under the influence of microbial enzymes, nitro groups, which are part of the drug molecules, are reduced to amino groups. The latter are very toxic to foreign microorganisms. By influencing bacteria, they destroy their cell membranes and also stop many processes occurring in them. As a result, parasites lose the opportunity to further grow and develop.

Reviews of the drug say that it also has minor immunostimulating properties, which are due to the ability of this drug to increase the phagocytic activity of leukocytes. The drug Furazolidone causes increased sensitivity of the human body to ethyl alcohol. For this reason, when a patient simultaneously takes these pills and drinks alcohol, side effects such as nausea and vomiting occur. Furazolidone and alcohol are incompatible, so during therapy it is necessary to completely avoid drinking alcohol.

The development of resistance to the active substance of the drug occurs quite slowly.

When taken internally, Furazolin quickly and almost completely dissolves in the intestines. Levels of the substance sufficient for a therapeutic effect remain for about six hours after the dose is taken. The drug enters the cerebrospinal fluid and its content there will be the same as in the plasma. An increased concentration of the active substance will also be observed in the intestines.

The drug is excreted from the body by the kidneys, in most cases in its original state, sometimes in the form of metabolites.

Indications for use

Furazolidone is prescribed for diarrhea and other symptoms of diseases caused by intestinal infections. Among these diseases are E. coli, dysentery, typhoid, paratyphoid and others. In this case, you can achieve the best effect by taking the antibiotic and enterosorbents in turn.

Loose stools are not necessarily an indicator of an intestinal infection, therefore, they are not always an indication for taking Furazolidone. The drug is effective only against bacteria (many, but not all), so the ideal situation would be in which a person has been tested and knows exactly what disease he wants to cure.

Otherwise, you need to focus not only on diarrhea, but also on other symptoms of intestinal infection. They can manifest themselves in different ways, but most often the following symptoms are observed simultaneously or separately:

• increased body temperature;
• vomit;
• weakness;
• blood in stool.

In addition to diarrhea, indications for taking the medicine are infections of the genitourinary system and damage to infected skin.

In what cases is it used?

Parents should know exactly when to use Furazolidone. Full information on this issue is given in the instructions for the drug, but it is better to repeat it again and remember it.

Indications for use:

1. Gastrointestinal infections of various natures, including rotavirus, food, paratyphoid, dysentery. With severe symptoms of poisoning (diarrhea, vomiting).
2. For giardiasis and other diseases caused by parasites.
3. Infections of the genitourinary system, which include pyelitis, cystitis, Trichomonas urethritis.
4. Wounds and burns infected with infection.

READ ALSO: What can you give a child who is vomiting at 3 years old?

Numerous studies have revealed the active destructive effect of the product on the following bacteria and parasites:

• Gram-positive and gram-negative bacteria, including salmonella. Consequently, the drug successfully fights intestinal infections, typhoid fever, paratyphoid fever, and salmonellosis.
• Shigella, which is the culprit of dysentery (we recommend reading: how is dysentery treated in children?).
• Giardia, parasites that live in the rectum and lead to a dangerous disease, giardiasis.
• Trichomonas, causing infection in the child’s genitourinary system.

Contraindications

The drug should not be taken if the kidneys are impaired, since it is excreted through the urinary tract. Furazolidone has a negative effect on the liver, so if you have cirrhosis or other lesions of this organ, you should not take this antibiotic.

The product contains lactose monohydrate, so if you are deficient in lactase (the enzyme that breaks down lactose), you should not take it. Contraindications also include allergic reactions to any of the components or to another antibiotic from the nitrofuran group, pregnancy, breastfeeding and children under one year of age.

People of retirement age and those who suffer from a deficiency of enzymes for the breakdown of glucose (diabetes), have an imbalance of water and electrolyte balance (hyperhydration, that is, excess water, or dehydration, that is, dehydration) and anemia should be treated with special caution when taking the drug. , since the drug can negatively affect blood cells

Side effects

The drug is slightly toxic. However, it can also lead to a variety of side effects. Particular discomfort in the gastrointestinal tract, nausea, vomiting, sharp or dull pain in the abdominal cavity, and lack of appetite may occur.

Possible manifestations of an allergic reaction, skin itching, Quincke's edema, rash, urticaria.

Doctors recommend taking B vitamins together with taking Furazolidone. To prevent unwanted side effects, the drug should be taken with plenty of water and at the same time take antihistamines. This will avoid an unwanted allergic reaction to the medicine.

Overdose

If furazolin is taken in doses exceeding the dosage recommended by the instructions for use, a person may experience severe liver damage, sometimes acute hepatitis.

No special antidotes have been created. In case of overdose, you will need to rinse your stomach and drink a sorbent or a salt-based laxative. If necessary, infusion treatment is prescribed to help restore water and electrolyte balance. When intoxication is very severe, hemodialysis is performed - a procedure during which toxic substances are eliminated from the body.

Composition of tablets and granules of the drug Furazolidone

The drug Furazolidone is produced by manufacturers in the form of tablets and granules. Both forms contain the following excipients:

• potato starch;
• calcium stearate;
• sucrose;
• polysorbate;
• lactose (milk sugar).

The tablet form is intended for the treatment of infectious inflammation of the bladder in adults. Granules for preparing the solution are used in children.

Furazolidone is available in the form of tablets and granules

Pregnancy

A drug

during pregnancy, it should be taken strictly as prescribed by the attending physician, who must carefully weigh the expected benefits for the mother and the potential risks for the fetus.

If it is necessary to use the drug during lactation, the issue of possible interruption of breastfeeding should be addressed, since furazolidone passes into breast milk and can cause the development of hemolytic anemia and methemoglobinemia in infants.

Side effects

The drug "Furazolidone" is a low-toxic drug. But despite this, it can still contribute to the development of adverse reactions. These include nausea, lack of appetite, vomiting and epigastric pain.

According to the instructions, this medication rarely leads to allergic reactions. Sometimes, against the background of its prima, urticaria, skin rash, Quincke's edema and severe itching develop.

To prevent the occurrence of adverse reactions, it is recommended to take each dose of the drug with a large volume of liquid, and, if necessary, take B vitamins and antihistamines.

With long-term use of tablets, especially in young children, the development of hemolytic anemia, methemoglobinemia, hyperthermia, shortness of breath, cough and a neurotoxic reaction is possible.

Properties of the drug

Due to the ability to form combined compounds with nucleic acids, furazolidone disrupts protein synthesis in bacterial cells, as a result of which the process of their reproduction and growth is inhibited.

The immunostimulating property of the drug in question is due to its ability to increase phagocytic activity and leukocyte complement titer. Furazolidone also reduces the production of toxins by bacteria, resulting in an improved overall clinical picture.

General characteristics of the drug

Furazolidone belongs to the category of drugs with a pronounced antimicrobial and bacteriostatic effect. Additionally, it stops inflammatory processes. The drug is active against gram-negative aerobic microorganisms (Escherichia coli, staphylococci, shigella), protozoa and chlamydia. Fungi and anaerobic microorganisms are less susceptible to Furazolidone.

Furazolidone, as an antibiotic from the nitrofuran series, has broad antibacterial properties, but is more effective against pathogenic microflora in the lower digestive tract. The drug is characterized by low toxicity compared to antibiotics from the fluoroquinolone group (Ofloxacin, Ciprofloxacin).

The drug is available in several forms - tablets, soluble granules and suppositories (only by individual prescription). The tablet form is more common and is prescribed more often. The tablets are round, yellow. Each contains 50 or 100 mg of active substance. In pharmacies, the drug is presented in ordinary paper plates or in blisters.

An important advantage of Furazolidone is the ability to combine its use with other antimicrobial agents (Tetracycline). Simultaneous use with herbal herbal preparations for cystitis (Fitolysin, Urolesan) increases the effectiveness of therapy, accelerating recovery.

Furazolion: contraindications

Antibiotics have a large number of contraindications, which does not indicate the low quality of the medicine, but its knowledge.

Contraindications for use as treatment with Furazolidone:

1. Renal failure in the stage of decompensation.
2. Acute liver dysfunction.
3. Glucose-6-phosphate dehydrogenase deficiency.
4. Pregnancy.
5. Breastfeeding period.
6. Age up to 8 years.
7. Allergic drugs to the components of the tablets (potato starch, milk sugar, aerosil, calcium stearate).

What does it help with?

The medicine is effective in fighting infections that affect the gastrointestinal tract and organs of the urinary system. The drug has a gentle effect on the child’s body and does not affect the functioning of the central nervous system. The drug has antimicrobial and antiprotozoal effects. It is prescribed to patients who have been diagnosed with an infectious disease. Furazolidone successfully copes with the following bacteria:

1. Gram-positive and gram-negative. The medication is prescribed to kill salmonella and shigella. These bacteria cause various intestinal infections, including paratyphoid, typhus, salmonellosis, and dysentery.
2. Giardia. These are simple infections that parasitize the cavity of the small intestine. As a result, the disease giardiasis develops.
3. Trichomonas. They belong to the group of protozoan bacteria that provoke trichomoniasis and diseases of the genitourinary system.

If we take other antimicrobial drugs , Furazolidone suppresses infections faster and activates the immune system.

This is interesting! How to take Enterol: instructions for use for adults

The composition of the drug includes the main potent substance - furazolidone. It is a derivative of nitrofuran. Auxiliary elements include potato starch, calcium stearate, lactose, polysorbate Tween-80, sucrose.

Available in several forms. Patients can purchase tablets or granules to make their own suspension. For young children, it is best to buy the drug in the form of a suspension for precise dosing .

Furazolidone tablets

Furazolidone tablets: price, reviews

The price of this product is not very high. You can buy 20 antibacterial tablets for 40-50 rubles.

What do consumers say about the drug "Furazolidone"? Every patient who has ever used it can leave a review of this medicine. According to the majority, the medication in question is particularly effective in the treatment of diseases of the genitourinary system. After several days of taking the tablets, the symptoms of cystitis, urethritis and other pathological conditions immediately disappear. As for side effects, they occur extremely rarely.

Analogues and price of the drug

If the use of Furazolidone is impossible, it is replaced with a drug from another pharmacological group that has a similar effect. The selection of a similar drug is carried out by the attending physician. Azithromycin, Ciprofloxacin, Rifaximin, Fluoroquinolone, Nifuroxazide have a similar effect.

You can purchase the medicine at a pharmacy without a doctor's prescription . The average price for a package of medicine is from 60 rubles.

Interaction with other medications

Before using any medicine, you need to know how it interacts with other drugs to avoid complications. If we talk about the compatibility of furazolidone with other drugs, the following should be noted:

• When furazolidone is used simultaneously with sedatives, tyramines, amphetamines, and sleep aids, an increase in blood pressure may occur.
• With alcohol-containing tinctures, blood pressure may be reduced, there is a risk of increased body temperature, as well as mental disorders.
• When used together with drugs with a saturated alkaline composition, the effectiveness of furazolidone may decrease. Conversely, products containing saturated acids help increase the effectiveness of this medication.

To prevent the occurrence of side effects due to the simultaneous use of incompatible drugs, you should consult a doctor before starting treatment.

Reviews

Patients note the effectiveness of furazolidone for bacterial diarrhea and infections of the genitourinary system. Rapid improvement is achieved due to the short absorption time of the main component. Important: improvement in condition is not a sufficient reason for making an independent decision to stop the course of antibiotic therapy. In this case, there is a particularly high risk of developing a relapse of the disease, requiring a second course of antibacterial therapy.

The most common use of the medicine is in the treatment of urinary tract infections. Reviews of the use of furazolidone for cystitis are predominantly positive. Practitioners pay special attention to the narrow list of contraindications and adverse reactions.

Read further: How to take probiotics when taking antibiotics and which ones are better

• About
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Yulia Peshkova

Certified specialist, in 2019 she graduated with honors from the Orenburg State University with a degree in microbiologist. Graduate of the graduate school of the Federal State Budgetary Educational Institution of Higher Education Orenburg State Agrarian University. In 2015 At the Institute of Cellular and Intracellular Symbiosis of the Ural Branch of the Russian Academy of Sciences, she completed advanced training in the additional professional program “Bacteriology”. Laureate of the All-Russian competition for the best scientific work in the category “Biological Sciences” 2019. Author of many scientific publications.

Operating principle

What are Furazolidone tablets? Instructions and reviews from experienced specialists indicate that this is a very effective antibacterial agent.

The effect of the drug in question directly depends on the dosage taken. When using a small amount of furazolidone, it has a bacteriostatic effect. If the dosage is increased, the bactericidal activity of the drug is noted.

It should also be said that this medication can have an immunostimulating effect.

The principle of the antimicrobial action of this medicine lies in the ability of the nitro groups of furazolidone under the influence of bacterial enzymes to be restored to the amino group. The elements formed as a result of this process have a toxic effect. They disrupt the integrity and structure of the cell membrane, and also block the biochemical processes occurring in bacteria.

After using Furazolidone, inhibition of tricarboxylic acids and irreversible blockade of NADH is observed. As a result, the respiration of microbial cells and the functioning of the cytoplasmic membrane are disrupted. After this, the death of bacteria occurs.

How to use the drug correctly

The drug is to be used only internally. The tablet must be swallowed completely. Chewing and crushing of the medicine is not allowed. In this case, the effectiveness of action will be reduced, and the drug is much less absorbed in the intestines. The dosage depends on the disease.

On average, a ten-day course is prescribed for the treatment of foodborne infections. You need to drink 150 grams four times a day.

For infected burns, a solution is used to treat open wounds. Typically, this drug is used only in hospitals and hospitals, where they use their own concentration of the drug, depending on the individual characteristics of the patient.

Use of the drug Furazolidone for cystitis

The tablets are taken orally. Chewing and crushing the drug is not recommended. Furazolidone should be taken with plenty of water. The medicine is best taken after meals.

To prepare the solution, the granules are diluted with boiled water using the measuring cup included in the kit. The child should be given the drug after meals. This form of medication is used for children under five years of age.

The doctor selects the course of treatment and dosage of the drug individually.

Treatment of cystitis with Furazolidone

The use of an antibiotic requires breaks during administration, after which tests are immediately carried out. First of all, the alternation of food intake and medication is learned - Furazolidone is taken before meals and washed down with a glass of clean water. Let's consider treatment tactics - how to take furazolidone for cystitis and in what dosages.

Treatment regimen (100 mg every 6 hours):

• three days of admission;
• break 3 days;
• three days of admission;
• taking tests.

To achieve the required concentration, it is enough to take only 2 tablets at a time. During the therapeutic course, the dosage does not change, however, in mild cases, the total number of tablets can be reduced (the course duration is either 3 or 6 days). The maximum daily dose allowed by the instructions for use of Furazolidone includes the permissibility of taking no more than 16 tablets (dosage 50 milligrams). To enhance the effectiveness of the product, the method of application is adjusted: high levels of salt and spices are excluded from food, and diuretic herbs are taken at the same time.

In order not to harm the young body, the manufacturers of furazolidone indicate in the instructions other treatment tactics for children when treating cystitis. For 1 kilogram of a child’s weight, 10 mg of furazolidone is prescribed (but no more than two tablets to take at a time). Medical specialists allocate the total treatment time for children no more than three days.