The reproductive function is responsible for the state of women's health, and the indicator of its proper functioning is considered, first of all, the stability of the menstrual cycle. Every woman has repeatedly faced a situation when her critical days began at the most inopportune moment: at an interview, on a first date or at a business meeting. And if this problem is easily eliminated with the help of the necessary hygiene products, then a more serious problem is when menstruation does not come on time. In such cases, experts recommend taking duphaston to induce menstruation.
The main reasons for the lack of a regular menstrual cycle
Based on the experience of many years of practice, gynecologists identify the following reasons that provoke cycle irregularity and amenorrhea:
- young age, when the cycle is just establishing (the first year after menarche);
- hormonal imbalance caused by menopausal changes in premenopause;
- period after childbirth (first 6 weeks plus while breastfeeding)
- current pregnancy;
- anovulation caused by a short-term failure in the pituitary gland and delay of menstruation;
- diseases of the endocrine system;
- acute inflammatory diseases of a viral, bacterial or fungal nature;
- inflammatory diseases of the genitourinary area;
- gynecological hormonal diseases;
- errors in nutrition: insufficient amount of food consumed, unbalanced diet;
- excess body weight or sudden weight loss;
- termination of pregnancy (spontaneous or artificial);
- taking hormonal drugs;
- great physical activity;
- stressful situations.
The effectiveness of treatment depends on making the correct diagnosis and further action plan aimed at eliminating the cause of the imbalance.
Knowing why amenorrhea occurs (complete cessation of menstruation), it is possible to conduct a targeted diagnosis and find the cause of this condition in a short time.
Reasons for delay
Delays often occur during menstruation.
There are many factors that can cause a delay in menstruation:
- it is most likely that the girl is pregnant - if the delay is more than two weeks, it is necessary to take a pregnancy test. It is important to remember that even the use of contraceptives does not provide a 100% guarantee that a girl will not become pregnant.
- A woman who has recently given birth also does not have menstruation for the next two months. This is because the uterine surface needs to heal and recover from the recent birth.
- an unstable cycle is considered normal in adolescence for the reason that the hormonal background has not yet formed due to a sharp change in hormone levels. If a girl is worried about the unexpected arrival of her period or, conversely, its delay two years after the start of her first menstruation, she should consult a doctor.
- Stressful situations, excessive physical activity or sudden climate change can cause the lack of ovulation. This deviation is not considered dangerous if it does not exceed 2-3 cases per year.
- exhausting diets provoke disruptions in the cycle, and the formation of a severe rash on the face, chest and back is also possible.
- Excess weight can cause hormonal imbalance.
The reasons for this group are much less common:
- interrupted pregnancy;
- side effect from contraceptives that contain hormones;
- development of menopause;
- diseases of the female organs.
Operating principle of Duphaston
The effective effect of the drug is explained by the presence in its composition of the active dydrogesterone, which is a progestogen. This active substance is an analogue of natural progesterone. It is devoid of estrogenic, corticoid and androgenic effects, and does not interfere with the establishment of the date of the ovulation process due to the lack of influence on basal temperature indicators. Duphaston also does not affect the ovulation process itself.
Duphaston for irregular cycles does not have side effects, as with the use of synthetic progestins. Its effectiveness has been confirmed when administered orally. The selective ability of the drug to act on progestin receptors located in the uterine mucosa allows Duphaston to be used to restore the cycle without threatening a woman’s reproductive health. If estrogen saturation levels in the body are achieved, it promotes normal epithelization of the endometrium. The drug is often prescribed at the planning stage of pregnancy, as well as in the first trimester to preserve it.
The high bioavailability of Duphaston due to the rapid absorption of the drug by the digestive system, complete excretion from the body by the kidneys within 3 days after administration, as well as the lack of cumulative properties of its presence in organs and systems allows patients suffering from renal failure to drink Duphaston.
How does duphaston work?
The active ingredient of Duphaston is dydrogesterone. One tablet contains 10 mg. A feature of dydrogesterone is its similarity in structure, chemical and pharmacological effects with natural progesterone. Since dydrogesterone is not a derivative of testosterone, it does not cause the side effects inherent in most synthetic progestogens derived from androgens (excessive hair growth or deepening of the voice).
Also, the drug does not have anabolic activity (does not increase protein synthesis and muscle mass), does not affect the production and metabolism of glucocorticoids and temperature, including basal temperature (for example, when taking COCs, there is no point in measuring basal temperature). Dydrogesterone supports the beneficial effects of estrogens on blood lipids, but differs in that it does not affect blood clotting. Also, dydrogesterone does not have a negative effect on carbohydrate metabolism and liver function.
Dydrogesterone replenishes the deficiency of its own progesterone in the body, that is, it promotes the “unfolding” of the second phase of the cycle - it loosens the endometrium, preparing it either for implantation of the egg or for rejection (menstruation). Thus, duphaston reduces the increased risk of endometrial hyperplasia or cancer due to excess estrogen, which is observed with long and regular delays in menstruation.
Feasibility of application
Amenorrhea, in which the cycle may be delayed by 2-3 days, usually does not cause concern for the fair half of humanity, but in the absence of menstruation for a long period, it is worth thinking about existing problems. If menstruation does not occur within a week or this problem recurs frequently, you should consult a doctor. A consultation with a gynecologist and confirmed test results will indicate an effective technique to restore the disorder.
The use of Duphaston makes it advisable in the following cases:
- luteal phase deficiency;
- endometriosis;
- threat of miscarriage;
- menstrual irregularities;
- pronounced premenstrual syndrome (PMS);
- secondary amenorrhea due to gynecological diseases;
- in order to prevent negative effects on the uterine mucosa due to estrogen intake;
- as replacement therapy for surgical interventions (removal of the uterus, appendages, ovaries).
When menstruation is delayed, Duphaston gently eliminates the insufficient level of estrogen in the female body. A delay in taking Duphaston can be easily eliminated with minor hormonal dysfunction. Duphaston is one of the few highly active drugs that can be used among all age categories. Rational use of the drug allows you to regulate the menstrual cycle and helps eliminate many problems associated with imbalance of hormones in the body.
How to take Duphaston to induce menstruation? To induce menstruation, you need to drink Duphaston, adhering to the treatment regimen. The standard scheme, which allows you to normalize the menstrual cycle, is used in most cases. It involves the use of Duphaston 10-20 milligrams per day, divided into two doses. The start of therapy is indicated from the 11th day from the start of menstruation. The duration of use reaches up to the 25th day of the cycle.
An important point: before starting therapy, you should donate blood for hCG or do a test to make sure there is no pregnancy. Delayed menstruation may be associated with conceiving a child. If you receive a negative result, you must start taking Duphaston according to the regimen prescribed by your doctor.
For more significant disorders, it is necessary to drink Duphaston in combination with estrogens. The inclusion of ethinyl estradiol in the treatment regimen at a dose of 0.05 milligrams confirms its effectiveness after 3 months of use. Duphaston for normalizing the cycle pleases with the results after one month of use, but you should not stop treatment with the medicine. Any changes in the regimen must be adjusted by the attending physician.
In the absence of menstruation, Duphaston is used depending on the reason for the absence of menstruation. Therapy can be continued for up to six months. This duration is indicated for pronounced premenstrual syndrome, painful and heavy periods. In any case, Duphaston tablets are taken based on the phase of the menstrual cycle and individual characteristics, clinical manifestations of the disease.
The scheme for using Duphaston is presented in the table:
Pathological condition | Application diagram | Course of therapy |
Infertility | 10 mg per day from 14 to 25 days of the cycle | 6 months |
Threatened miscarriage | 40 mg once and then 10 mg every 8 hours | until symptoms disappear with gradual withdrawal of the drug |
Habitual miscarriage | 10 mg 2 times a day | up to 16-20 weeks of pregnancy with gradual withdrawal of the drug |
PMS | 10 mg 2 times a day from days 11 to 25 of the cycle | until the condition normalizes |
Irregular menstruation | 10 mg 2 times a day from days 11 to 25 of the cycle | until the condition normalizes or pregnancy occurs |
Dysfunctional uterine bleeding (treatment) | 10 mg 2 times a day | 5-7 days or until bleeding stops |
Dysfunctional uterine bleeding (prevention) | 10 mg 2 times a day from days 11 to 25 of the cycle | 3-6 months |
If your period comes too early
Sometimes a woman, without finishing taking the prescribed amount of pills, observes bloody marks on her underwear. If your periods started ahead of schedule while taking Duphaston, then the reason may be the following:
- Adverse reaction of the body.
- Lack of dose.
- Violation of the dosage regimen.
- Second phase displacement.
Without the help of a doctor, it is impossible to accurately determine the cause of unscheduled discharge. It is imperative to take tests and undergo comprehensive diagnostics.
Non-dangerous reason
A hormonal drug based on dydrogesterone must be taken within a certain period. But not all women have a cycle of 28 days, and according to most schemes, the last pill falls on the 25th day. After three days, menstruation should begin.
But if the cycle is shorter, then menstruation appears earlier, falling at the time of taking it. There is nothing terrible about this, but it would be best to visit a doctor to adjust the therapy according to the duration of the cycle.
Side effect
Can menstruation begin while taking Duphaston? Gynecologists answer this question in the affirmative, but during therapy there is a high risk of bleeding, which can easily be confused with menstruation. Premature bleeding is often caused by a negative reaction of the body to the drug. You should not quit treatment on your own. A woman must adhere to the following action plan:
- Continue taking pills that day.
- Visit a medical facility immediately.
- Get tested.
Based on the data obtained, the woman will need to either stop the course of treatment to choose another remedy, or increase the amount of the substance per day.
Continuous use
Stopping taking the pills is appropriate only with your doctor's permission. But continuous use of the product is unacceptable. If a woman continuously takes synthetic progesterone, its effectiveness decreases.
Will my period come if I drink Duphaston continuously? In such a case, you should not expect normal menstruation; only bleeding or spotting is possible.
Is it possible to drink Duphaston during menstruation?
Due to its characteristics and existing dosage regimens, a drug containing synthetic progesterone cannot be used during menstruation. After all, its purpose is to stabilize the hormonal balance in a certain period of time, that is, before the start of monthly menstrual flow.
Delay, early menstruation or uterine bleeding is a reason to consult a doctor.
When treating menstrual problems, you cannot use the experience of other women. When reading comments on the site, you must take into account that violations in each individual case are caused by different reasons. Therefore, some patients take Duphaston from days 5, 6 to 25 of the cycle, and others from days 11, 14, 16 to 25. Only an experienced specialist will be able to correctly determine the cause of the disorder and adjust subsequent treatment.
Active ingredient: dydrogesterone
.
One tablet contains 10 mg of dydrogesterone. The uniqueness of the drug duphaston
given by the fact that during its production the progesterone molecule is slightly modified, as a result of which duphaston, while maintaining almost complete identity with endogenous progesterone, even in low doses is 20 times more active than progesterone. In addition, it is more stable in the body, which allows it to maintain a stable concentration of this substance over time.
When using duphaston, the frequency of premature termination of pregnancy is reduced by 2 times, in addition, placental insufficiency, hypoxia and fetal growth retardation syndrome occur less frequently. No birth defects have been reported associated with the use of this drug. In particular, it does not cause masculinization of the genital organs (enlargement of the clitoris) in female fetuses, and feminization (appearance of female characteristics) in male fetuses. Usually, to maintain pregnancy, 2 tablets of duphaston (20 mg) per day are used, but in some cases the dose may be increased. The use of duphaston after 20 weeks of pregnancy is undesirable.
Dydrogesterone is not a derivative of the male sex hormone testosterone, like many of its predecessors, so its use does not cause many side effects. It does not affect the condition of the skin, hair and voice of a pregnant woman. In addition, unlike natural progesterones, it does not cause drowsiness, does not change the lipid spectrum and the concentration of glucose in the blood. Side effects when used outside of pregnancy include intermenstrual bleeding from the genital tract, which can be prevented by increasing the dose of the drug. Any changes in the nature of discharge during pregnancy are a reason to immediately seek medical help!
Contraindications
: hypersensitivity to the components of the drug. Prescribe with caution if there are indications of skin itching during previous pregnancy. The drug is incompatible with phenobarbital drugs. Dydrogesterone is excreted in breast milk, so breastfeeding while taking duphaston is not recommended.
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Does Duphaston have contraceptive properties?
Is Duphaston a contraceptive? Can the drug be considered as a birth control pill? You can give an affirmative answer - no.
This medicine does not have a contraceptive effect. It is not capable of causing spontaneous abortion and does not threaten termination of pregnancy. On the contrary, it promotes pregnancy by maintaining normal progesterone levels. Women taking the drug to prevent pregnancy do not achieve their goal with dydrogesterone stimulation.
The drug is prescribed for infertility if there is progesterone deficiency. If pregnancy cannot occur within a year of regular sexual activity, the doctor may recommend taking Duphaston. A daily dose of 20 milligrams is divided into two doses at equal intervals from the 11th to the 25th day of menstruation. Therapy is continued for up to 6 months. If pregnancy is confirmed, there is no need to stop taking the drug. The doctor adjusts the dose based on examination and examination data. Usually, it corresponds to that prescribed for fetal loss.
In cases where recurrent miscarriage is observed, Duphaston can be effective in a daily dosage of 10-40 milligrams, taken according to the classical regimen. Taking the drug continues for up to 14-16 weeks continuously (daily). Do not suddenly stop taking the drug. Abrupt withdrawal of Duphaston can cause a miscarriage. The correct thing to do would be to consult a doctor and follow the proposed scheme for gradual withdrawal of the medication.
What are periods
Menstruation is a natural physiological process in the female body that lasts from 3 to 7 days. The cycle must be at least 21 days and no more than 35 days and includes two stages:
- The initial stage occupies the first four days of the cycle - the endometrium is born on it, which begins to increase in size, which leads to the maturation of the follicles. The maximum amount of estrogen provokes the release of a mature egg - this is ovulation.
- At the final stage, the uterus is ready to receive a fertilized egg. If implantation is unsuccessful and the girl does not become pregnant, her period will begin.
Use during pregnancy and lactation
The insignificant presence of side effects makes the use of Duphaston during pregnancy rational. How long you need to take the medicine will be determined by your pregnancy doctor. The drug helps to carry out pregnancy in the early stages with progesterone deficiency. After 16 weeks, the placenta takes over the production of progesterone, and the need for hormonal support disappears.
In the case of a threatened abortion, the gynecologist may recommend a starting dose of 40 milligrams, which is taken once. The remainder of the medicine is divided into doses of 10 milligrams, consumed after 8 hours. The course of treatment is continued for a week. If the threat resumes, the dose can be adjusted upward. Duration of treatment reaches 3 months. The rationality of using the drug is valid if endogenous progesterone deficiency is accurately confirmed.
Regarding the lactation period, there are contraindications for treatment with Duphaston, since the active substance of the drug passes into breast milk. Therefore, breastfeeding should be stopped during treatment. If urgent treatment is necessary, the doctor may replace Duphaston with another drug suitable for nursing mothers.
Indications for use
Duphaston is prescribed for various abnormalities in the functioning of the female body caused by a lack of progesterone. There are several main situations when correction of hormonal balance with this drug is necessary:
- Hormonal imbalances identified based on test results at the stage of pregnancy planning. Lack of progesterone can cause infertility; prescribing Duphostan will help overcome problems with conception and minimize the risks of complications in the first trimester of pregnancy.
- Multiple cases of termination of pregnancy at its initial stage. The cause of this pathology is most often a dysfunction of the corpus luteum, in which progesterone is synthesized. As a result, the uterine endometrium does not develop normally, it loses the ability to retain the attached fertilized egg.
- Endometrial proliferation , which occurs as a result of a lack of progesterone in the body. This condition threatens its detachment and massive bleeding. Duphaston acts on the receptors of the uterine mucosa, preventing the pathological process. The danger of the disease lies in the possibility of degeneration of enlarged endometrial cells into cancerous ones.
The use of the drug in such situations does not affect the menstrual cycle and does not interfere with the implantation of a fertilized egg in the event of pregnancy.
- During pregnancy, Duphaston can be prescribed if there is a threat of miscarriage due to increased tone of the uterine muscles . In addition, progesterone prepares the female body for the lactation period and improves the condition of the uterine lining, thereby preparing it for the upcoming birth.
- Irregularity of the menstrual cycle and severe pain in the lower abdomen a few days before the onset of menstruation and at the beginning of menstruation . This condition is often associated with changes in hormonal balance, and the use of these tablets helps in solving these problems.
- Polycystic ovary syndrome. The cause of this pathology in most cases is also a hormonal imbalance, in particular, insufficient production of progesterone. During pregnancy that occurs against the background of polycystic ovary syndrome, there is a high probability of termination in the early stages or premature birth in the later stages.
The cycle of a woman with PCOS (polycystic ovary syndrome)
To prevent such conditions in the first trimester, the prescription of Duphaston may be indicated; in later stages, progesterone synthesis occurs in the placenta, which to a certain extent normalizes the hormonal balance.
- In some cases, this remedy may be part of a complex of therapy for menopause. In this case, it is prescribed to correct hormonal levels and alleviate unpleasant symptoms during menopause.
For information on the use of progesterone during pregnancy, watch this video:
Contraindications and side effects
Medical statistics have not recorded cases of incompatibility of the drug with drugs from other groups, however, it has been noted that the simultaneous use of phenobarbital or rifampicin reduces the clinical effect of Duphaston when menstruation is delayed. Its use is also contraindicated in cases of Rotor or Dabin-Johnson syndrome.
Restrictions on use include patients with chronic kidney disease, vascular disease, heart disease, diabetes mellitus, and severe headaches. The skin itching caused by the drug during pregnancy excludes the possibility of its further use. Regular examination by a mammologist is a mandatory procedure for women taking this medication. A rare, but observed during menstruation, side effect is breakthrough bleeding, requiring an increase in the dose taken. You should also not forget about individual intolerance to the drug.
Common side effects include:
- scanty bleeding from the vagina;
- headache;
- soreness of the mammary glands;
- swelling;
- jaundice;
- allergic reaction.
If any undesirable symptoms appear, you should stop taking the drug.
When is it possible to induce menstruation?
In the case of regular delays in menstruation, constantly artificially provoking their onset is illiterate and even criminal. Such an irregular cycle may hide serious endocrine diseases: hypothyroidism, pituitary prolactinoma, adrenal tumors and others. To clarify the reasons for such an irregular cycle, it is necessary:
- Donate blood for thyroid, adrenal and sex hormones.
- Check blood sugar levels and glucose tolerance levels.
- Perform an ultrasound examination of the thyroid gland and pelvis, and sometimes the abdominal organs.
- Monitor the presence of ovulation using special tests, basal temperature or ultrasound.
Constantly prescribing medications to such patients and, without understanding the reason for the absence of normal menstruation, inducing menstruation is an indicator of the indifference and illiteracy of the attending physician.
The use of special medications is justified in the case of a one-time delay in a gynecologically healthy patient. Such delays can occur due to stress or climate change. In some cases, it is permissible to wait one or two weeks, perform a pelvic ultrasound, assess the condition of the ovaries and endometrium, and only then prescribe drugs to provoke a menstrual reaction.
It is important to understand that the only proven group of medications that can in some cases cause delayed menstruation are gestagens and gestagen-like drugs. Today we will talk about Duphaston as the safest and most widely used to provoke a menstrual reaction.
Analogue drugs
Medicines with similar effects include:
- Utrozhestan:
- Iprozhin;
- Prajeesan;
- Crinon;
- Norkolut.
The price of the drug Duphaston is about 500 rubles. If necessary, the doctor can select cheaper analogues.
Analogs
If the reason for the absence of menstruation is a hormone imbalance, then the modern pharmaceutical market offers to eliminate this problem with the help of the drug Duphaston. Instructions for use for delayed menstruation will provide a detailed analysis of this medication.
How many days will it take to get your period when taking Duphaston?
When the norm is reached, the drug is not immediately discontinued. Usually, the dose is gradually reduced. Abrupt withdrawal leads to a new delay or, on the contrary, heavy bleeding. Exceeding 7-9 months or drinking Duphaston continuously is also fraught. The body, receiving progesterone from the outside, may stop producing it on its own, which will lead to even greater problems in the future.
Reviews of Duphaston for delayed periods
After reading reviews about girls taking Duphaston when their periods are late, we can note a fairly common occurrence when bleeding did not start. Sometimes this is due to the individuality of the body, and it is also possible that the synthetic hormone is not homogeneous with the woman’s body.
Sometimes menstruation began earlier than the period specified in the instructions, which is also explained by individual perception. Ladies also note the effectiveness of Duphaston for delayed menstruation in premenopause.
Girls in reviews of taking Duphaston with a delay in menstruation note its positive aspects that: the drug does not cause adverse reactions, menstruation comes immediately after the start of taking it and it is not so painful
If, during the course of treatment, a girl discovers pregnancy, you should not immediately stop taking the drug. It is not capable of causing a miscarriage or negatively affecting the development of the embryo, but a sudden interruption of the course can lead to dire consequences if there is not enough natural hormone in the woman’s body. It is better to immediately consult your gynecologist. He will change the dose or select a different drug, if necessary.
If a girl discovers she is pregnant and takes Duphaston during a delay to restore her cycle, under no circumstances should you stop taking the drug, at least until the next consultation with a gynecologist.
Side effects
After reading the instructions for use for delayed menstruation about Duphaston, you can pay attention to several types of adverse reactions:
- Headache, dizziness;
- Pain during menstruation;
- Heavy bleeding (occurs in every 10th patient);
- Chest pain is sufficient, typical due to the effects of progesterone;
- Individual allergic reactions: rash, nausea, fever.
Negative consequences are very rare, as the instructions say. Confirmation of this can also be found on women’s forums from the girls who received it.
The main reasons for the lack of a regular menstrual cycle
Based on the experience of many years of practice, gynecologists identify the following reasons that provoke cycle irregularity and amenorrhea:
- young age, when the cycle is just establishing (the first year after menarche);
- hormonal imbalance caused by menopausal changes in premenopause;
- period after childbirth (first 6 weeks plus while breastfeeding)
- current pregnancy;
- anovulation caused by a short-term failure in the pituitary gland and delay of menstruation;
- diseases of the endocrine system;
- acute inflammatory diseases of a viral, bacterial or fungal nature;
- inflammatory diseases of the genitourinary area;
- gynecological hormonal diseases;
- errors in nutrition: insufficient amount of food consumed, unbalanced diet;
- excess body weight or sudden weight loss;
- termination of pregnancy (spontaneous or artificial);
- taking hormonal drugs;
- great physical activity;
- stressful situations.
The effectiveness of treatment depends on making the correct diagnosis and further action plan aimed at eliminating the cause of the imbalance.
Knowing why amenorrhea occurs (complete cessation of menstruation), it is possible to conduct a targeted diagnosis and find the cause of this condition in a short time.
Duphaston and menstruation
Any hormonal drug should be taken only as prescribed by a doctor and according to a certain schedule, but sometimes women, in the absence of menstruation, begin to take it on their own in the hope of regulating the cycle and causing the onset of menstrual periods.
Such uncontrolled interference in the functioning of the endocrine system can lead to even more serious disruptions in its functioning, which subsequently will require long-term treatment to normalize the hormonal balance.
Duphaston can affect the menstrual cycle in different ways, but usually, with strict adherence to the dosage regimen and prescribed dosage, periods come on time, only occasionally a delay of several days is possible.
If the critical days have not arrived after taking it, then the reasons may be as follows:
- a significant decrease in the concentration of estrogen in the blood;
- dysfunction of the endocrine system, for example, thyroid disease or ovarian problems;
- delayed ovulation with late endometrial renewal.
In some cases, menstruation may begin earlier than expected, this may be due to the following factors:
- violation of the drug dosage regimen, for example, the patient starts taking pills in the first phase of the cycle;
- individual response to therapy;
- wrong dosage.
Sometimes women during treatment complain of heavy bleeding during menstrual periods, which is often caused by endometriosis. In such cases, the doctor selects other drugs to treat the pathology.
There are also cases when menstruation becomes too scanty. This occurs as a result of irregular use of pills or against the background of pregnancy.
For any deviations from the normal course of menstruation, consultation with your doctor is mandatory.
Operating principle of Duphaston
The effective effect of the drug is explained by the presence in its composition of the active dydrogesterone, which is a progestogen. This active substance is an analogue of natural progesterone. It is devoid of estrogenic, corticoid and androgenic effects, and does not interfere with the establishment of the date of the ovulation process due to the lack of influence on basal temperature indicators. Duphaston also does not affect the ovulation process itself.
Duphaston for irregular cycles does not have side effects, as with the use of synthetic progestins. Its effectiveness has been confirmed when administered orally. The selective ability of the drug to act on progestin receptors located in the uterine mucosa allows Duphaston to be used to restore the cycle without threatening a woman’s reproductive health. If estrogen saturation levels in the body are achieved, it promotes normal epithelization of the endometrium. The drug is often prescribed at the planning stage of pregnancy, as well as in the first trimester to preserve it.
The high bioavailability of Duphaston due to the rapid absorption of the drug by the digestive system, complete excretion from the body by the kidneys within 3 days after administration, as well as the lack of cumulative properties of its presence in organs and systems allows patients suffering from renal failure to drink Duphaston.
When do menstruation begin after stopping Duphaston?
Menstruation after Duphaston normally occurs during a break in treatment. A drug with an artificially created hormone (dydrogesterone) is prescribed after the ovulatory period to maintain the luteal phase.
Next, at the end of the cycle, you need to pause. It is at this time that you can expect monthly bleeding. Normally, your period comes 2-3 days after taking the last dose.
But due to the individual characteristics of the body, deviations of up to a week are allowed for the medicine.
And we must also not forget that the hormonal drug has a strong effect on the reproductive system. Therefore, Duphaston-based therapy may provoke unexpected changes in the monthly cycle due to:
- side effects;
- individual reaction;
- excessively small or large dose of the hormone;
- hidden pathologies;
- abnormalities of the genital organs.
Feasibility of application
Amenorrhea, in which the cycle may be delayed by 2-3 days, usually does not cause concern for the fair half of humanity, but in the absence of menstruation for a long period, it is worth thinking about existing problems. If menstruation does not occur within a week or this problem recurs frequently, you should consult a doctor. A consultation with a gynecologist and confirmed test results will indicate an effective technique to restore the disorder.
The use of Duphaston makes it advisable in the following cases:
- luteal phase deficiency;
- endometriosis;
- threat of miscarriage;
- menstrual irregularities;
- pronounced premenstrual syndrome (PMS);
- secondary amenorrhea due to gynecological diseases;
- in order to prevent negative effects on the uterine mucosa due to estrogen intake;
- as replacement therapy for surgical interventions (removal of the uterus, appendages, ovaries).
When menstruation is delayed, Duphaston gently eliminates the insufficient level of estrogen in the female body. A delay in taking Duphaston can be easily eliminated with minor hormonal dysfunction. Duphaston is one of the few highly active drugs that can be used among all age categories. Rational use of the drug allows you to regulate the menstrual cycle and helps eliminate many problems associated with imbalance of hormones in the body.
How to take Duphaston to induce menstruation? To induce menstruation, you need to drink Duphaston, adhering to the treatment regimen. The standard scheme, which allows you to normalize the menstrual cycle, is used in most cases. It involves the use of Duphaston 10-20 milligrams per day, divided into two doses. The start of therapy is indicated from the 11th day from the start of menstruation. The duration of use reaches up to the 25th day of the cycle.
An important point: before starting therapy, you should donate blood for hCG or do a test to make sure there is no pregnancy. Delayed menstruation may be associated with conceiving a child. If you receive a negative result, you must start taking Duphaston according to the regimen prescribed by your doctor.
For more significant disorders, it is necessary to drink Duphaston in combination with estrogens. The inclusion of ethinyl estradiol in the treatment regimen at a dose of 0.05 milligrams confirms its effectiveness after 3 months of use. Duphaston for normalizing the cycle pleases with the results after one month of use, but you should not stop treatment with the medicine. Any changes in the regimen must be adjusted by the attending physician.
In the absence of menstruation, Duphaston is used depending on the reason for the absence of menstruation. Therapy can be continued for up to six months. This duration is indicated for pronounced premenstrual syndrome, painful and heavy periods. In any case, Duphaston tablets are taken based on the phase of the menstrual cycle and individual characteristics, clinical manifestations of the disease.
The scheme for using Duphaston is presented in the table:
Pathological condition | Application diagram | Course of therapy |
Infertility | 10 mg per day from 14 to 25 days of the cycle | 6 months |
Threatened miscarriage | 40 mg once and then 10 mg every 8 hours | until symptoms disappear with gradual withdrawal of the drug |
Habitual miscarriage | 10 mg 2 times a day | up to 16-20 weeks of pregnancy with gradual withdrawal of the drug |
PMS | 10 mg 2 times a day from days 11 to 25 of the cycle | until the condition normalizes |
Irregular menstruation | 10 mg 2 times a day from days 11 to 25 of the cycle | until the condition normalizes or pregnancy occurs |
Dysfunctional uterine bleeding (treatment) | 10 mg 2 times a day | 5-7 days or until bleeding stops |
Dysfunctional uterine bleeding (prevention) | 10 mg 2 times a day from days 11 to 25 of the cycle | 3-6 months |
Question answer
I had a long delay, the pregnancy test was negative. The doctor prescribed me to take duphaston. After finishing the treatment, a dark spotting discharge began, which lasted only 2 days. This is fine?
Yes, after the first course of taking the drug, periods do not last long and are quite scanty, which is explained by incomplete proliferation of the endometrium, that is, the uterine mucosa was not yet completely ready for rejection, since the functional layer of the endometrium had not reached the required thickness. After taking Duphaston for three months, the menstrual cycle will even out and menstruation will become more intense and longer.
After stopping duphaston, my period did not start on the 5th or 7th day. The pregnancy test is questionable. What to do?
Of course, first of all, it is worth excluding/confirming pregnancy, donating blood for hCG and performing an ultrasound of the uterus. In 90% of cases, pregnancy is confirmed.
The doctor prescribed me duphaston for a long delay, but after stopping the drug, menstruation did not begin. What is this connected with?
If pregnancy is 100% excluded, then perhaps your estrogen level is too low, which did not cause proliferation of the endometrium in the first phase, and, accordingly, could not spur the second – secretory phase of the cycle. Thus, the endometrium turned out to be “immature” and not at all prepared for desquamation - menstruation. It is necessary to examine the level of estrogen in the first phase and the content of progesterone in the second and adjust the treatment of the disrupted menstrual cycle with estrogen and progesterone preparations.
Does taking duphaston increase weight?
The drug enhances metabolic processes, that is, it accelerates the absorption of nutrients, which can “stimulate” appetite and provoke weight gain. When treating with duphaston, physical inactivity should be avoided and appetite controlled, then the weight will remain at the same level. There may be some increase in body weight due to peripheral edema, but they disappear with the onset of menstruation on their own.
Is it possible to drink alcohol while being treated with duphaston?
Drinking alcoholic beverages is not advisable (but not prohibited) during treatment with duphaston. The drug is metabolized in the liver, and alcohol accelerates this process, so the therapeutic effect of duphaston may decrease due to alcohol consumption.
Does Duphaston have contraceptive properties?
Is Duphaston a contraceptive? Can the drug be considered as a birth control pill? You can give an affirmative answer - no.
This medicine does not have a contraceptive effect. It is not capable of causing spontaneous abortion and does not threaten termination of pregnancy. On the contrary, it promotes pregnancy by maintaining normal progesterone levels. Women taking the drug to prevent pregnancy do not achieve their goal with dydrogesterone stimulation.
The drug is prescribed for infertility if there is progesterone deficiency. If pregnancy cannot occur within a year of regular sexual activity, the doctor may recommend taking Duphaston. A daily dose of 20 milligrams is divided into two doses at equal intervals from the 11th to the 25th day of menstruation. Therapy is continued for up to 6 months. If pregnancy is confirmed, there is no need to stop taking the drug. The doctor adjusts the dose based on examination and examination data. Usually, it corresponds to that prescribed for fetal loss.
In cases where recurrent miscarriage is observed, Duphaston can be effective in a daily dosage of 10-40 milligrams, taken according to the classical regimen. Taking the drug continues for up to 14-16 weeks continuously (daily). Do not suddenly stop taking the drug. Abrupt withdrawal of Duphaston can cause a miscarriage. The correct thing to do would be to consult a doctor and follow the proposed scheme for gradual withdrawal of the medication.
Characteristics of Duphaston
As a rule, drug therapy can cope with disruptions in the menstrual cycle. In most cases, doctors advise using Duphaston for delayed periods. Dydrogesterone is a high-quality drug; its amount in one tablet should not exceed 10 milligrams.
The excitement surrounding the drug is due to the fact that it effectively compensates for the lack of progesterone, acting as its high-quality substitute. Despite the fact that the medicine contains hormones, it does not provoke reproductive failures.
In addition, taking Duphaston does not put the metabolic process at risk - it does not make any changes to its functioning, does not increase the temperature, and is not harmful to the liver and other vital organs.
The most common question is whether girls who are preparing to conceive can take Duphaston. Experts answer the question positively, arguing that the useful component of the drug helps normalize hormones and promotes a comfortable stay for the fetus in the uterus.
Another important advantage of Duphaston is that it provokes weight gain and can be taken without fear for your figure. Girls will also be pleasantly pleased with the price, which is set at an average level and therefore accessible to almost everyone. The price in Ukraine does not exceed 410 hryvnia.
Use during pregnancy and lactation
The insignificant presence of side effects makes the use of Duphaston during pregnancy rational. How long you need to take the medicine will be determined by your pregnancy doctor. The drug helps to carry out pregnancy in the early stages with progesterone deficiency. After 16 weeks, the placenta takes over the production of progesterone, and the need for hormonal support disappears.
In the case of a threatened abortion, the gynecologist may recommend a starting dose of 40 milligrams, which is taken once. The remainder of the medicine is divided into doses of 10 milligrams, consumed after 8 hours. The course of treatment is continued for a week. If the threat resumes, the dose can be adjusted upward. Duration of treatment reaches 3 months. The rationality of using the drug is valid if endogenous progesterone deficiency is accurately confirmed.
Regarding the lactation period, there are contraindications for treatment with Duphaston, since the active substance of the drug passes into breast milk. Therefore, breastfeeding should be stopped during treatment. If urgent treatment is necessary, the doctor may replace Duphaston with another drug suitable for nursing mothers.
How to stimulate menstruation if the drug is late
Before your appointment, you must undergo a full examination to determine the cause of the absence of menstruation. First of all, you need to make sure there is no pregnancy.
If the results of a hormonal analysis indicate an insufficient level of progesterone in the blood, the doctor may prescribe 1 tablet for five days if the critical days are delayed. Menstruation may begin immediately after starting to take the drug or immediately after the end of the course.
If the regularity of the cycle could not be established in one course, then it should be carried out over several months, taking the drug one tablet daily from the 11th to the 25th day of the cycle. After this course of therapy, the menstrual cycle is usually completely restored.
Contraindications and side effects
Medical statistics have not recorded cases of incompatibility of the drug with drugs from other groups, however, it has been noted that the simultaneous use of phenobarbital or rifampicin reduces the clinical effect of Duphaston when menstruation is delayed. Its use is also contraindicated in cases of Rotor or Dabin-Johnson syndrome.
Restrictions on use include patients with chronic kidney disease, vascular disease, heart disease, diabetes mellitus, and severe headaches. The skin itching caused by the drug during pregnancy excludes the possibility of its further use. Regular examination by a mammologist is a mandatory procedure for women taking this medication. A rare, but observed during menstruation, side effect is breakthrough bleeding, requiring an increase in the dose taken. You should also not forget about individual intolerance to the drug.
Common side effects include:
- scanty bleeding from the vagina;
- headache;
- soreness of the mammary glands;
- swelling;
- jaundice;
- allergic reaction.
If any undesirable symptoms appear, you should stop taking the drug.
Side effect
Taking duphaston may be accompanied by a number of side effects.
- First of all, during treatment with this drug, breakthrough uterine bleeding may occur, which is eliminated by increasing the dose of the drug.
- Changes in the hematopoietic system and the development of hemolytic anemia are also possible (rare).
- A number of women note the appearance of headaches or migraines, and increased sensitivity of the mammary glands.
- The occurrence of allergic reactions (both rash and in rare cases) cannot be ruled out.
- Possible liver dysfunction (weakness or malaise, etc.).
- And extremely rarely, duphaston provokes the development of edema of the extremities.
Analogue drugs
Medicines with similar effects include:
- Utrozhestan:
- Iprozhin;
- Prajeesan;
- Crinon;
- Norkolut.
The price of the drug Duphaston is about 500 rubles. If necessary, the doctor can select cheaper analogues.
Duphaston's analogues
Utrozhestan, which contains micronized progesterone of a natural nature, obtained from plant materials, eliminates the obvious clinical manifestations of the disease and has no restrictions during pregnancy.
Iprozhin and Prajisan are synthetic analogues of progesterone, produced for oral and intravaginal use. Crinon gel allows you to administer artificially synthesized progesterone, which causes epithelization of the vaginal mucosa against the background of hormonal imbalance.
In some cases, Norkolut based on norethisterone has a similar effect. Regular intake of Norkolut according to the regimen corrects hormonal imbalances. If treatment is ineffective, estrogen medications can be taken as additional therapy.
Unlike analogue drugs, Duphaston does not have sedative properties; it can be used when driving vehicles and in situations requiring concentrated attention.
Duphaston has proven its effectiveness in treating delayed periods and has become a recognized drug for the treatment of hormonal disorders of reproductive function. As an introduction, Duphaston provides detailed instructions for using the product, but only a doctor should prescribe the method and treatment regimen.
The drug Utrozhestan, which contains micronized progesterone of a natural nature, obtained from plant materials, eliminates the obvious clinical manifestations of the disease and has no restrictions during pregnancy.
Iprozhin and Prajisan are synthetic analogues of progesterone, produced for oral and intravaginal use. Crinon gel allows you to administer artificially synthesized progesterone, which causes epithelization of the vaginal mucosa against the background of hormonal imbalance.
In some cases, Norkolut based on norethisterone has a similar effect. Regular intake of Norkolut according to the regimen corrects hormonal imbalances. If treatment is ineffective, estrogen medications can be taken as additional therapy.
Unlike analogue drugs, Duphaston does not have sedative properties; it can be used when driving vehicles and in situations requiring concentrated attention.
conclusions
Duphaston has proven its effectiveness in treating delayed periods and has become a recognized drug for the treatment of hormonal disorders of reproductive function. As an introduction, Duphaston provides detailed instructions for using the product, but only a doctor should prescribe the method and treatment regimen.
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Duphaston analogs
There are a number of drugs whose mechanism of action is similar to duphaston. A distinctive feature of all of the listed duphaston analogues is their ability to cause lethargy and drowsiness and reduce concentration.
The active substance of this medicine is natural micronized progesterone, which is obtained from plant materials. Utrozhestan is available in gelatin capsules, which are taken either orally (orally) or administered intravaginally. One capsule contains 100 active substances. The dose for treatment is selected individually in each specific case and depends on the form of the disease and the severity of clinical symptoms. Utrozhestan, like Duphaston, can be taken during pregnancy. Price: 28 pcs 410 rub.
The active ingredient of the drug is progesterone, obtained synthetically. Iprozhin is also available in capsules, which can be taken orally or administered intravaginally. One capsule contains 100 mg of progesterone. Price: 15 pieces 380 rub. |
Crinone is available in gel form. One applicator contains 1.125 g. artificially synthesized progesterone. The applicators are inserted into the vagina. Price: Crinon 2200-2700 rub. |
This drug also contains synthetic progesterone, 100 or 200 mg per capsule. Oral and intravaginal administration of prajisan is allowed. Price: 10 pcs. 270 rub. |
What is the menstrual cycle
In women, starting from adolescence, the regularity of menstruation indicates a normal state of health and the absence of pregnancy. Therefore, if there is a delay, an adult woman begins to worry.
In gynecology, a normal cycle is a time period that is determined from the first day of the last menstruation until the first day of the next. If it lasts from 21 to 35 days, and the discharge lasts three to seven days, then there is no reason to worry.
The cycle itself is divided into two main phases:
- follicular,
- luteal
A specific hormone is responsible for each phase. All these hormonal changes are necessary in order to prepare the female body for pregnancy. If for any reason pregnancy does not occur, then menstruation begins.
Duphaston to induce menstruation - how to take?
It is worth remembering that this drug is hormonal. Before drinking Duphaston to induce menstruation, a woman must make sure that the reason for their absence is definitely a hormonal imbalance.
To do this, you need to see a doctor and undergo appropriate treatment. In addition, before starting to take the drug, you must make sure that there is no pregnancy: taking the drug may affect its course.
More often, women use Duphaston when their periods are late, but it can also be used to induce menstruation ahead of schedule. However, there are differences in the pattern of drug use and duration of treatment.
- violation of the regularity of menstruation;
- change in the volume of menstrual blood;
- increase or decrease in the duration of menstruation.
Duphaston can be used if the next menstruation is delayed if menstruation is absent for a week or more. In this case, it is necessary to exclude the possibility that untimely menstruation is not caused by a stress factor, physical fatigue, or pregnancy.
But even if there is an occasional delay, doctors advise not to rush to take hormonal medications. Changes in the frequency and frequency of menstrual flow, occurring no more than 3 times a year, are considered to be a variant of the norm.
If cycle disturbances are permanent, after examination the woman is prescribed a course of therapy. To eliminate the delay caused by a lack of progesterone, Duphaston can be prescribed, which is taken for no more than 10 days.
Often in life, women are faced with a situation where it is necessary to bring the day of menstruation closer. An important trip or vacation sometimes occurs during your period. In order not to change their plans, women use Duphaston to stimulate menstruation.
Doctors have a negative attitude towards measures aimed at accelerating the arrival of the next menstruation. Even using Duphaston tablets once to induce menstruation, a woman affects the functioning of the endocrine system in this way.
- cycle disorders;
- changes in the volume of menstruation;
- lack of menstruation.
https://www.youtube.com/watch?v=5ubrndT_Jtk
Before using Duphaston to induce menstruation, a woman should consult a doctor. Only after examination and diagnostic procedures, during which the cause of the delay is established, do doctors prescribe the drug.
Taking Duphaston to induce menstruation is stopped after it starts. However, in some cases, when the delay is caused by strong hormonal changes, if the cycle is disrupted, the drug may be prescribed for a longer time.
At the same time, doctors take into account the fact that progesterone synthesis in the body decreases due to the constant use of its synthetic analogue. To prevent this, when taking Duphaston therapy, take a break after using the medicine for 2-3 months in a row.
How is the drug useful?
There is constant debate among doctors about the effect of the drug on the female body.
British doctors banned the hormonal drug almost 10 years ago. Domestic doctors successfully use it and deny negative effects on a woman’s body, provided, of course, that all rules of administration, dosage and tests are followed.
One of the confirmed facts recorded in medicine states that Duphaston can significantly reduce the likelihood of relapses of inflammation and prevent the development of cancerous tumors of the female organs.
https://youtu.be/LLpEovLV3i0
Delayed menstruation occurs at least once in every woman’s life. If menstruation does not start once, then this is not considered a pathological deviation; this can happen due to the effects of changing atmospheric pressure. But if delays are regular, then this is already a deviation from the norm. In this case, you should contact a gynecologist.
Under no circumstances should you take Duphaston if your menstruation is delayed. This medicine is hormonal. An excess of hormones in the body can cause negative consequences. The dosage and duration are prescribed only by a doctor, after a test is carried out on the level of hormones in the woman’s blood.
Insufficient progesterone production is a common reason for menstruation to arrive at the wrong time. But this symptom is also typical for many other gynecological diseases, so self-medication or increasing the dose prescribed by the gynecologist is under no circumstances allowed.
Doctors almost always prescribe Duphaston to induce menstruation and restore the cycle. If the rules of administration are not violated, the woman follows the dosage, then the drug perfectly restores hormone levels and does not have side effects on the body.
Doctors do not recommend inducing menstruation on your own using folk remedies. Some recipes may cause uterine bleeding.
Contraindications
A mandatory examination before taking Duphaston for amenorrhea must also be carried out for the reason that the drug has contraindications. A hormonal drug is not prescribed if a woman is diagnosed with pathologies of the liver, kidneys, or has cardiovascular diseases. For problems with the gallbladder and in the presence of benign and malignant neoplasms, Duphaston is also not prescribed to induce menstruation.
https://youtu.be/0wJcEw-EV1A
Many women who cannot get pregnant chart their basal temperature. At the same time, it is not recommended to take Duphaston, because under its influence the basal temperature changes and the data will not be informative and correct.
If you have an allergy, your body may react. In this case, the Duphaston dosage regimen and dosage will differ from the standard one. If the body is intolerant of the components, the drug is not prescribed.
If a woman experiences delays during breastfeeding, hormonal medication is not prescribed, as it passes into the milk.
https://youtu.be/s4oXuUUTWbY
Possible cycle changes
If you do not have your period after taking Duphaston, you should seek help from a doctor and find out the reason for the delay. This can be triggered by climate change, emotional stress, excessive physical stress, and also due to the onset of pregnancy. Taking the drug during menstruation may cause a shift in the onset of the next menstrual cycle, especially if Duphaston was taken to speed up or delay the onset of discharge.
For pregnant patients, after taking the drug in the early stages, a negative test is possible, and menstrual delays are caused by an erroneous diagnosis. In any case, timely consultation with a doctor is important, and in the future it is necessary to follow all his instructions. This is especially true for patient complaints about:
- too heavy periods;
- presence of spotting instead of menstruation;
- uncharacteristically scanty periods.
Uncontrolled use of hormonal drugs is extremely dangerous, and doctor’s prescriptions should be followed only after examination and a blood test for hormones. As a rule, your period comes towards the end of the first course of treatment. Any observed result of treatment is discussed in advance with the doctor.