Vitamins Pharmstandard MAGNELIS B6 FORTE TOMSKHIMPHARM, OJSC - reviews

Every mother knows about the weakening of the immune system and the lack of useful microelements after childbirth, especially since almost every second woman acutely feels this problem herself. Magnesium is no exception and, like many other elements, is necessary for a nursing mother. Taking Magnelis B6 while breastfeeding will help replenish its supply. How to take the drug correctly? In what cases is the drug contraindicated? The answers to these and many other questions are of interest to every woman who cares about her health.

Indications for use

Magnelis B6 is a more inexpensive Russian analogue of the French-made drug Magne B6. Despite the fact that the Russian analogue is inferior in price, the spectrum of action and composition of these products is identical. Both drugs are based on the properties of pyridoxine and magnesium. Magnelis B6 has a good reputation, and gynecologists equally often prescribe these drugs.

The most relevant use of this drug is during pregnancy, since during this period the female body is subjected to serious stress and suffers from a lack of important microelements and vitamins. The lack of nutrients must be compensated externally by taking medications.

Taking Magnelis B6 can minimize the risks of pathological development of the fetus and ensure normal growth.

It has the following effects on the child’s body:

  • against the formation of blood clots;
  • against inflammation;
  • against the development of arrhythmia;
  • antispasmodic.

The drug can completely cope with almost any manifestation of vitamin deficiency. At the same time, it does not cause harm to an unformed child, but before use it is better to consult a specialist, because the mother may have an individual intolerance to the constituent substances.

Harm

Magnelis B6 has restrictions on use. It is not recommended for renal failure (moderate is allowed) and phenylketonuria. Also limited is children under 1 year of age. Problems with administration may occur in people with impaired transport of glucose and fructose, as well as other components of the drug. Usually the drug does not cause side effects or discomfort.

It is recommended to keep it at home in order to take it in a timely manner; this is a good way to protect yourself from the harmful effects of stress and avoid many diseases. Doctors also prescribe other drugs in this group.

Chemical composition

As an active component, Magnelis B6 includes magnesium lactate and pyridoxine, the content of which in one tablet reaches 480 mg and 6 mg, respectively. The action of magnesium lactate in the structure is aimed at normalizing the metabolic processes of incoming substances and eliminating the lack of magnesium.

Pyridoxine or vitamin B6 is involved in metabolic processes, restores the functioning of the nervous system (both central and peripheral), participates in redox processes and is a participant in the secretion of enzymes.

In addition, the drug contains additional substances:

Component nameComponent action
SucroseWhen entering the body, it breaks down into glucose and fructose, which subsequently become a source of energy necessary for the child’s growth and development.
PovidoneIt has an absorbent effect and is aimed against intoxication of the body.
Kollidon SR (silica, polyvinyl acetate and sodium lauryl sulfate)Has a detoxifying effect (including antidotes)
Magnesium stearateIt is included in the composition of the drug as a binding auxiliary element, which gives the mixture homogeneity. It is also an additional source of magnesium.
Carmellose sodiumIncluded in Magnelis B6 to improve its dissolution after ingestion.
TalcEnsures the tablet slides along the esophagus and prevents it from sticking to the walls of the stomach.

The shell consists of the following components:

  • disaccharide;
  • protein (gelatin);
  • white type of clay;
  • minerals (talc);
  • wax (beeswax);
  • wax (carnauba);
  • titanium dioxide;
  • acacia gum.

The content of all components is balanced so that their action complements each other and has no side effects as far as possible.

What is included in the drug and its release form

Magnelis B6 is produced in the form of coated tablets. One tablet contains magnesium lactate (470 mg) and pyridoxine hydrochloride (5 mg).

The composition of the drug is supplemented by other active substances: sucrose, talc, magnesium stearate, etc. The vitamin complex is produced in two variations:

  1. Small jars, they contain 60 tablets or 90.
  2. Cardboard packages contain 3 or 5 strips of 10 tablets.

The main active ingredient, magnesium lactate, is considered an antispasmodic, has an antiplatelet effect, due to which neuromuscular tissue is restored. Recommended for replenishing magnesium in professional athletes, with increased mental stress, and also during pregnancy.

The second active component, pyridoxine hydrochloride, is considered a toxic substance, but the drug contains it within the permissible dosage and does not have a negative effect on the body. With it, magnesium is better absorbed and distributed throughout the cells.

In what form is it produced?

Maglelis B6, which is taken during pregnancy, is produced in the form of tablets to be taken by swallowing. They are completely enclosed in a protective shell in the form of a whitish film. The tablet has an oblong-round shape, convex on both sides.

The product can be placed in:

  • a polymer jar (60 tablets), located in a cardboard box (cost 390 rubles);
  • a polymer jar (90 tablets), located in a cardboard box (cost 620 rubles);
  • contour wrappers with cells with 10 tablets, placed in 3 pieces. in a cardboard pack (price 290 rub.);
  • contour wrappers with cells with 10 tablets, placed in 5 pieces. in a cardboard pack (price 40 rubles).

Magnelis B6 is not produced in the form of suspensions, solutions or mixtures for injection.

Dosage forms of Magnesium B6 preparations: dosage and time of administration

In case of magnesium deficiency, the doctor prescribes Magnesium B6 preparations in the form of tablets or solution.

Tablets are sold in packs of 30 or 50 pieces. The daily dose during pregnancy and lactation is prescribed by the doctor individually, on average it is 4-6 tablets per day. The duration of the full course is one month.

The tablets contain:

  • magnesium salt of lactic acid;
  • vitamin B6 (pyridoxine hydrochloride);
  • excipients such as sugar, white clay, magnesium stearate, etc.

The tablets must be taken with a sufficient amount of water.

Taking Magnesium B6 reduces the rate of absorption of tetracycline antibiotics, so when used together, the minimum interval between doses of the drugs should be three hours.

Another dosage form of magnesium is an oral solution .

The recommended dose of solution for an adult is 3-4 ampoules per day. Before taking, the ampoule is dissolved in 100 ml of water.

Both tablets and solution are taken with meals.

Pharmadynamics

The drug is aimed at eliminating magnesium deficiency in the patient’s body during pregnancy. Magnesium belongs to a group of important elements that are an integral part of major organs and tissues and are used for adequate cell functioning.

He also takes part in such processes as:

  • regulation of nervous system signal transmission;
  • contractile muscle work;
  • transport of substances.

Magnesium enters the body along with the food consumed. Its deficiency can be detected in the case of an incorrectly composed diet, increasing the need for magnesium during intense physical and intellectual overload. Also, a lack of magnesium can occur due to pregnancy, stress, or the use of diuretic medications.

Pyridoxine or vitamin B6 is involved in a large number of substance transport processes and restoration of the central nervous system. This vitamin also helps improve the absorption of magnesium in the digestive system and better penetration into the cell.

What medications are it not recommended to take Magnelis B6 with?

To compensate for the lack of magnesium during lactation, the components of the drug must be dissolved in the body and absorbed in a certain way. But there are a number of medications that interfere with the absorption of magnesium when taken in parallel with Magnelis B6. This:

  • calcium-containing products and medications that contain phosphates. They interfere with the penetration of magnesium into cell membranes,
  • drugs from the tetracycline category. Their effect is simply absent if magnesium is taken at the same time. They can be combined, but then you need to take a break of at least three hours between taking each tablet,
  • complex products based on iron. Magnesium interferes with the absorption of beneficial microelements intended to treat anemia,
  • levodopa, since one of the components of Magnelis, pyridoxine, interferes with the full effect of this medicine.

To avoid the negative consequences of medication incompatibility, you should tell your doctor all your symptoms and a complete medical history. And also analyze hemoglobin indicators: if its value is low, magnesium will only aggravate the problem.

Pharmacokinetics

Magnelis B6 is taken orally and enters the stomach through the esophagus, where it is absorbed into the blood. The volume of absorption of magnesium entering the digestive system is no more than 50%. Residues of magnesium are excreted through the excretory system, mainly by the kidneys, where additional absorption of the substance occurs.

After the glomerular filtration process, the percentage of absorbed substance increases to 70%. Further, in the kidney tubules, magnesium undergoes additional filtration, where another 27% is absorbed. As a result, along the way magnesium travels through the body, 97% of the active substance is absorbed, half in the digestive organs, and the rest in the excretory system.

Instructions for use

This drug is prescribed to a person in cases where there is a lack of magnesium and vitamin B6 in the body.

Prescribe the drug up to eight tablets per day. For an adult, the minimum daily dose is equal to taking six tablets. For a child, the dosage is chosen slightly less: from 4 to 6 capsules per day. The prescribed dose must be divided into three doses. It is worth considering that you should not take this medicine until you are four years old. The only exceptions are cases when the benefits of treatment outweigh the risk of side effects.

The instructions recommend taking Magnelis B6 tablets with meals. This is necessary to achieve maximum effect. Since a person receives vitamins from food, it is during this period that the benefit from such a drug will be maximum. You need to take the tablets with plenty of clean, still water.

Depending on the reason that caused the lack of essential substances in the body, additional treatment may be carried out. What are the main factors that reduce the content of magnesium and vitamin B6 in the human body?

Application

Magnelis B6 is recommended for use not only by pregnant women. It can be drunk by all categories of people who have no contraindications for taking it. The indication for use is a lack of magnesium in the body. However, at different ages and health conditions there are special recommendations for using the drug.

For children under 18 years old

Magnelis B6 is contraindicated for children under 6 years of age. Upon reaching this age, you should take tablets according to the following scheme: 4-6 tablets every 24 hours. In this case, they need to be divided into 2 or 3 doses, that is, 2 tablets at a time. The drug should be taken with meals and washed down with plenty of 1 tbsp. water.

Therapy should be completed immediately after the level of magnesium in the body has returned to normal. Magnelis B6 is also prohibited for children who have reached the age of six but weigh less than 20 kg.

For adults

Adults should take Magnelis B6 2 or 3 times every 24 hours during meals, 2 tablets. Thus, the daily dose of the drug reaches 6 pcs. You need to take the tablets with plenty of water, 250 ml of water. Before taking the course, it is better to consult a doctor; you may need to prescribe an individual dosage for Magnelis B6, taking into account the level of magnesium in the blood serum.

It is also necessary to check for any contraindications.

For pregnant

Magnelis B6 during pregnancy is prescribed both during gestation and before the onset of this condition. It is recommended to start taking vitamins 90-120 days before conception to avoid a lack of magnesium in the mother's body. This will help the fetus develop correctly, without pathological abnormalities.

The daily consumption of the drug is 6 tablets, which should be taken 3 times a day, 2 tablets each. during meals, with plenty of water. It is better not to combine a course of Magnelis B6 with medications that contain calcium and iron. These substances interfere with mutual absorption. Taking calcium prevents magnesium from being absorbed into the blood, while magnesium blocks the absorption of iron.

Before taking it, you should consult a gynecologist to avoid possible side effects.

For the elderly

In old age, you can take any medications only after consulting a doctor, including Magnelis B6. Usually prescribed 6 tablets per day, 2-3 doses with meals. The medicine must be taken with a large volume of water.

Indications for taking Magnelis B6 for hepatitis B

Replenishing magnesium is an important part of caring for the health of a nursing woman, because its lack acutely affects the development of a newborn baby. If the magnesium contained in food products is not enough for the mother, then doctors recommend drinking magnesium while breastfeeding when vitamin deficiency occurs.

Magnelis B6 is considered one of the optimal medications. The Russian-made product effectively copes with the lack of a useful substance, replenishing its reserves. Some therapists refute this opinion, but if there is an acute shortage of a microelement in the body of a nursing woman, they still prescribe the drug for use. When breastfeeding, the drug is prescribed in the following cases:

  • the appearance of signs of a nervous system disorder, tremors in the fingers, convulsions or spasms,
  • unstable psycho-emotional state, fear, anxiety, increased excitability, excessive irritability or lethargy that occurs for no reason, apathy to everything that happens,
  • heart rhythm disturbances,
  • painful sensations in the epigastric region, problems with stool,
  • attacks of nausea or vomiting.

Already when some of the described symptoms appear, we can talk about a lack of magnesium in the body of a nursing woman. Most often, these indications for the use of Magnelis B6 must be expressed clearly enough for the therapist to prescribe the drug for guards. After all, most doctors are afraid of harming the baby and prescribe medication only in exceptional cases.

Contraindications

Taking Magnelis B6 is strictly contraindicated for children under 6 years of age and children over 6 years of age whose body weight is less than 20 kg.

Other contraindications for using the product include:

  • phenylketonuria;
  • allergy or high sensitivity to the components included in the drug;
  • severe renal failure with keratin clearance less than 30 ml/min.

Caution should be exercised in people suffering from mild renal failure, as there is a high likelihood of developing hypermagnesemia. Magnelis B6 can be taken during pregnancy, since the negative effect of the drug on the fetus is possible only with an overdose. When taken in moderation, the product only brings benefits.

However, consultation and appointment of a treating gynecologist is required. While breastfeeding, Magnelis should be stopped because it is excreted in breast milk and can harm the baby. If there is a need for a person suffering from diabetes to take Magnelis, it is worth remembering that it contains sucrase.

In this case, you need to carefully monitor your blood sugar levels. Also, magnesium intake should be completed if there is a need to replenish calcium in the body, because complex treatment in this case will be useless. Magnesium and calcium cannot be absorbed together.

Analogues of the drug during breastfeeding

The following structural analogues of the drug Magnesium B6 exist:

Magnelis B6

Available in the form of white biconvex film-coated tablets. Well-being is restored due to improved communication of neural connections. The mental state becomes more stable.

Magnelis has the same indications and contraindications as Magiy B6, but it should not be used together not only with tetracycline antibiotics, but also with drugs containing iron, phosphates and calcium. Do not use in patients with diabetes mellitus due to the sucrose contained in the drug. The drug is compatible with lactation in the same way as Magnesium B6.

Magnesium plus

This drug contains more microelements. It contains: folic acid, vitamin B12, magnesium carbonate and lactate. In this regard, the drug Magnesium Plus is not recommended during breastfeeding. The indications coincide with the drug Magnesium B6. The recommended daily dose is different: you need to take 1-2 pieces. in a day.

Bibliography:

  1. New descriptions of combinations of active ingredients - radar (updated 08/30/2017).
  2. Modern possibilities for correcting magnesium deficiency in obstetrics – Chushkov V.V. – “RMZh” No. 17 of 07/06/2012, p. 867.
  3. Magnesium Lactate and breastfeeding. Are they compatible? – E-Lactancia.org.

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Overdose

With normal functioning of the excretory system and kidneys, magnesium intake is not capable of causing a toxic reaction, even if the maximum permissible dosage is exceeded. A toxic result from taking Magnelis B6 is possible if the patient has renal failure. The degree of poisoning depends on the level of magnesium in the blood serum.

In case of intoxication, the following symptoms may appear:

  • a sharp decrease in blood pressure;
  • feeling of nausea;
  • the appearance of vomiting;
  • anuria;
  • slow breathing;
  • coma;
  • depression of the nervous system (decreased reflex speed);
  • heart failure.

If symptoms of poisoning occur, rehydration and forced diuresis are necessary. If the patient suffers from renal failure, peritoneal dialysis or hemodialysis will be required.

Magnesium and its role in the human body

Many people are susceptible to magnesium deficiency due to improper and unbalanced diet, unhealthy lifestyle, excessive physical and emotional stress. What can we say about the body of a woman who is breastfeeding, because most of the vitamins and nutrients during this period go to the baby along with mother’s milk.

Magnesium, as an important element for the human body, performs a number of functions:

  • replenishing the energy supply in the body’s cells and maintaining it at the required level. The element promotes the transfer of accumulated energy to all types of tissues, therefore, the more magnesium in the body, the more cheerful and healthy a person feels;
  • regulation of nerve impulses and reduction of excessive cell excitability. Thanks to this action, a person becomes calmer, reacts adequately to stressful situations, remains balanced and unexcited;
  • regulation of vascular tone - capillaries remain elastic, which maintains normal blood pressure levels in the system of veins and arteries;
  • maintaining the full functions of the nervous system and muscles - a sufficient amount of magnesium in the body helps to relax the heart muscle and prevents it from working “for wear and tear”;
  • strengthening the body's defenses - magnesium helps protect the immune system from attack and the introduction of pathogens, as well as allergens.

Expectant mothers begin to take complexes containing a beneficial element even during gestation, so that it is formed correctly, without defects and pathologies of the neuromuscular system. Therefore, doctors often prescribe magnesium to pregnant women, even for preventive purposes.

On a note! Magnesium is proportionally distributed in the tissues and systems of the body. Of the total incoming volume of the element, 4/5 is deposited in the bones and tooth enamel, 1/5 goes into muscle tissue, kidneys and heart. And only 1% of magnesium penetrates the circulatory system.

Foods High in Magnesium

A natural way to replenish magnesium in the body is to eat foods high in this element. Many cereals, herbs and nuts, animal products, as well as fresh and dried fruits are rich in it. The following are the foods with the highest microelement content (the amount per 100 grams of food is indicated):

  • wheat bran – 586 mg;
  • buckwheat – 290 mg;
  • cashew nuts – 270 mg;
  • beans – 130 mg;
  • fresh herbs, especially parsley;
  • hard cheeses;
  • persimmon.

Expectant mothers and women breastfeeding must include foods rich in magnesium in their daily diet to avoid a lack of this valuable element in the body.

Side effects

Magnelis B6 during pregnancy can cause allergic reactions in the form of redness on the skin, rash, swelling and itching. This effect is possible due to individual intolerance to the components included in the drug or exceeding the daily dosage.

You can get rid of this effect by stopping the medication, replacing it with a similar drug, or starting taking anti-allergy pills. It is necessary to consult a specialist to choose the most suitable option.

The following side effects may occur from the gastrointestinal tract:

  • sharp pain in the abdominal area;
  • bowel dysfunction (constipation);
  • feeling of nausea;
  • the appearance of vomiting;
  • flatulence.

In this case, symptomatic treatment with appropriate medications is required. They should be prescribed by a doctor, who should be contacted if any symptoms appear.

special instructions

The instructions for use of the drug contain a special instructions section, which should be studied especially carefully, since it contains important information:

  • the tablets contain sucrose, so you need to be careful when prescribing them to patients with diabetes;
  • with concomitant calcium deficiency, the magnesium deficiency should first be eliminated, and then treatment with calcium preparations should be started;
  • there is no evidence that the drug impairs concentration or the speed of psychomotor reactions, so it can be prescribed when driving or driving dangerous mechanisms;
  • If after a month of treatment there is no result, it is not advisable to continue therapy.

Drug interactions

The interaction of Magnelis B6 with drugs that contain phosphates or calcium salts causes a significant decrease in the absorption of magnesium in the gastrointestinal tract and excretory system. At the same time, the absorption of phosphates and calcium will remain the same.

Combined therapy with Magnelis B6 and tetricycline is not recommended, since the action of magnesium significantly reduces the effectiveness of the second agent. If the medications cannot be divided, the tablets should be taken at intervals of at least 3 hours.

During pregnancy, Magnelis B6 should not be used together with a drug such as tetricycline.

The effects of oral thrombolytic agents and drugs containing iron and its derivatives can be neutralized by taking Magnelis B6 and other magnesium drugs. Magnelis also inhibits the activity of levodopa. Magnelis can be taken with other drugs that are not listed here without fear that they will neutralize each other’s actions.

Pharmacology of the drug

Magnelis B6 Forte tablets (reviews note that the drug helps cure prolonged depression and strengthens the nerves well) replenish magnesium deficiency. This substance is simply necessary for the human body, because the microelement is involved in the work of cells responsible for metabolism. Involved in stabilizing the transmission of nerve impulses and appears in the contraction of muscle tissue. Half of the total amount of magnesium in the body is found in bone tissue.

The metal is involved in 350 reactions in the human body. It has a beneficial effect on the brain, nervous system, head and heart organ. Strengthens blood vessels. Affects energy and performance. Removes lethargy, depression and fights stress. Copes with limb cramps and prevents their occurrence in the future.

Pyridoxine, also known as vitamin B6, affects many metabolic processes in the body. Positively affects the absorption of magnesium in the gastrointestinal tract. Promotes faster penetration of metal into cells.

If the blood contains 12-17 mg/l of magnesium, then this is a moderate magnesium deficiency. If the amount of trace element in plasma is less than 12 g/l, then the person experiences severe magnesium deficiency. People receive magnesium at the same time as food. Its deficiency occurs due to poor and unhealthy nutrition, during a diet or during pregnancy.

Magnelis B6 Forte is an optimal complex for replenishing magnesium deficiency. Here the magnesium formula is as close as possible to natural. Therefore, the drug is easily absorbed and well tolerated by patients. Vitamin B6 accelerates the process of magnesium absorption by cells.

Clinical studies have proven that the product improves sleep, reduces anxiety signals, and eliminates leg cramps. During pregnancy, it reduces the tone of the uterus and calms the nervous system.

In the gastrointestinal system, the absorption of magnesium salts occurs passively. Here, salt solubility plays a critical role. The degree of absorption is not more than 50%. The drug is mostly excreted by the kidneys.

Reviews

According to patient reviews, taking Magnelis B6 has a beneficial effect on the body, which can be noticed already in the first days of use.

These results include:

  • improved sleep;
  • reduction of irritability and excitability;
  • improving hair quality;
  • disappearance of the feeling of fatigue.

Also, one of the advantages of the drug is its relatively low cost. However, there are also negative aspects that people take magnesium highlight. Compared to its more expensive analogue, Magne B6, Magnelis does not have such a pronounced and rapid effect on the body.

Similar means

Cheap analogues of the described product are:

  • "Magnesium plus B6";
  • "Magne B6" (tablets);
  • "Magnistad" (tablets);
  • "Magnicum" (in tablets) and others.

A specialist will indicate how long they need to be used. The benefits and harms of these drugs can be found out by studying the annotation to them. The dosage will also be prescribed there.

Analogs

Magnelis B6 is not the only drug that can combat magnesium deficiency in the body.

There are several products that are almost identical in composition and method of action:

Drug nameRelease formDosageTo whom it is recommendedPeculiarities _price, rub.
Magne B6Oral solution in the form of a clear brown liquid with a caramel odorDaily dose for adults: 3-4 ampoules containing 10 to 30 mg of magnesiumPeople with magnesium deficiency who suffer from sleep disturbances and increased irritabilityIs a strong allergen for people prone to allergic reactionsFrom 450
AngiovitisWhite biconvex film-coated tabletsDaily dose of 1 tablet containing up to 4 mg of vitamin B6People suffering from magnesium deficiency due to diseases of the cardiovascular system and high homocysteine ​​levelsCombines well with cardiac glycosidesFrom 220
BiotredinSublingual white or slightly yellowish tablets in the shape of a flat cylinder with a bevelDaily dose 2-3 tablets. One tablet contains up to 5 mg of magnesium People who suffer from disturbances in emotional stability and deterioration of brain function due to a lack of magnesiumNot recommended during pregnancy and breastfeedingFrom 110
Combilipen TabsWhite, film-coated, convex, biconvex tabletsDaily dose: 3 tablets containing up to 100 mg of magnesiumUsed in cases of development of pathologies of the central nervous system against the background of magnesium deficiencyContraindicated in the presence of heart failure and children under 16 years of ageFrom 210
Luxidon PlusOval capsulesDaily dose: 3 tablets containing up to 50 mg of vitamin B6They belong to the group of anti-tuberculosis drugs, but contain a large amount of vitamin B6Do not use if you have epilepsyFrom 230
Magnesium PlusEffervescent white tablets in the shape of a flat cylinder with a beveled edge. Have a slight specific odor Daily up to 2 tablets containing up to 200 mg of magnesium and 2 mg of vitamin B6People with sleep disorders, increased excitability and spasmsMay cause nausea and dizzinessFrom 170

Magnelis B6 is able to normalize the level of magnesium and vitamin B6 in the blood. You can take it both for microelement deficiency and for prevention. Taking the drug is especially useful for women during pregnancy, as it promotes the normal development of the fetus.

Article design: Ilchenko Okana

Why is Magnelis B6 prescribed to pregnant women?

So, Magnelis B6 is prescribed during pregnancy to compensate for the deficiency of magnesium and pyrodoxine in the body. The daily intake of magnesium for pregnant women is 350-700 mg, and pyridoxine - 2-2.2 mg.

READ IN DETAIL: Why are pregnant women prescribed Magnesium B6?

The biological role of magnesium is very great, so obstetricians and gynecologists first began to prescribe drugs based on it at the beginning of the twentieth century. This macronutrient:

  • required for protein synthesis;
  • necessary for the conversion of creatine phosphate into ATP, an important component of cellular energy metabolism;
  • required for the functioning of the nervous and cardiovascular systems - stimulates the functioning of the heart muscle, dilates blood vessels;
  • stimulates the excretion of bile;
  • accelerates intestinal function and promotes the removal of cholesterol from the body.

As for pyrodoxine, the second main component of the drug, its role is as follows:

  • participates in the formation of red blood cells;
  • helps nerve cells absorb glucose;
  • required for the normal functioning of metabolic processes;
  • needed to normalize liver function.

During pregnancy, due to hormonal fluctuations, magnesium deficiency often occurs, which negatively affects the state of the reproductive system and can lead to uterine tone. Also, indications for the use of Magnelis B6 or Magne Forte are:

  • risk of miscarriage;
  • the woman’s previous pregnancies were interrupted by miscarriages;
  • multiple pregnancy;
  • diabetes;
  • pathologies of the heart and blood vessels;
  • gastrointestinal ailments.

Sometimes doctors prescribe Magnelis B6 at the pregnancy planning stage. The expectant mother will be able to compensate for the lack of macronutrients in advance and prepare her body for bearing a child. The drug will help to successfully overcome stressful situations and improve the body's metabolic processes.

Analogues and generics

It's no secret that the pharmaceutical market offers drugs with the same composition at different prices. These drugs have different names and are produced by different manufacturers. As for magnesium preparations, there are also several of them. Here are just a few of them: Magnesium B6, Magne B6, Panangin, Asparkam, Magnerot, Magnelis B6 forte, Magnistad, etc.

Video: review of magnesium preparations

If a person wants to stay healthy, then he must ensure that his body, in addition to other beneficial substances, receives magnesium B6. If there is a deficiency of this microelement, it is necessary to adjust the diet or even resort to taking special medications. However, there is no need to take them thoughtlessly, since an overdose is no less dangerous for the body than a deficiency of this substance. The opinion that everything unnecessary will simply be eliminated by the body without causing any harm is erroneous. In order not to harm yourself, you need to carefully calculate the dosage, monitor the body’s reaction to taking medications, and consult a doctor.

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Foods as sources of magnesium

If there is a deficiency of magnesium in the body, an obstetrician-gynecologist can prescribe a pregnant woman to take Magnelis B6 and recommend her products that are rich in this mineral. It is worth noting that doctors’ opinions on the need to take magnesium supplements during gestation are quite contradictory, since some experts consider such additional drug therapy inappropriate.

A woman can receive magnesium and vitamin B6 in their pure form from food that is familiar and accessible to us, so the expectant mother should include in her diet:

  • nuts: almonds, cashews, walnuts, pistachios, hazelnuts, peanuts;
  • cereals: oatmeal, buckwheat, millet, barley;
  • beans (especially asparagus) and peas;
  • seaweed;
  • fish: tuna, mackerel, sardine;
  • liver and meat;
  • greens: parsley, spinach, dill, basil, mint;
  • dried fruits: raisins, dried apricots, prunes, dates;
  • sweet pepper and garlic;
  • pomegranates, bananas, avocados.

A pregnant woman can get magnesium in its pure form from food

Unfortunately, the quality of modern food products leaves much to be desired, so these days it is quite difficult to find dried fruits that are truly rich in magnesium. In the summer-autumn period, while relaxing at the dacha, I try to dry as many blueberries, plums, cherries, currants and apples as possible. For these purposes, I do not use an electric dryer or oven. The best option is open air, and the sun's rays should not fall on the berries and fruits. I prepare parsley and dill in the same way.

Magnesium during pregnancy

The daily requirement for magnesium in the body of an adult woman is 280 - 300 mg. During pregnancy, this figure increases by almost 20 - 30% and amounts to 340 - 350 mg. This is due, first of all, to the formation of new blood vessels, and therefore to an increase in blood volume, as the body begins to work with double the load, providing nutrients to mother and baby. Moreover, during gestation the excretion of magnesium by the kidneys increases.

Miscarriage is one of the main pathologies that occurs in obstetric and gynecological practice. This pathology accounts for 27% of the total number of complications. One of the reasons for its occurrence is considered to be magnesium deficiency, which occurs in almost 80% of pregnant women.

Causes and symptoms of magnesium deficiency during pregnancy

There are a number of factors that influence the decrease in magnesium levels in the body of the expectant mother:

  • severe toxicosis;
  • increased blood volume;
  • increased excretion of magnesium by the kidneys;
  • taking diuretics;
  • alcohol and smoking abuse. Although these bad habits are already prohibited during gestation;
  • poor nutrition;
  • diseases of the gastrointestinal tract;
  • early pregnancy;
  • stressful situations.

The main symptoms of hypomagnesemia are:

  • increased excitability and anxiety;
  • cramps of the calf muscles;
  • increased swelling;
  • insomnia;
  • fast fatiguability;
  • hypertonicity of the uterus;
  • increased activity of the baby, which may indicate oxygen starvation;
  • fast heart rate (100 to 400 beats per minute).

Magnesium acts as a kind of calcium antagonist. When there is a lack of magnesium in the body, calcium takes its place, which leads to overstrain and spasm of the smooth muscles.

The dangers of magnesium deficiency during pregnancy

A lack of magnesium during pregnancy can negatively affect both the development of the fetus, the course of pregnancy, and the condition of the woman herself. So, a deficiency of this microelement is fraught with:

  • intrauterine growth retardation;
  • premature birth or miscarriage;
  • pathologies of intrauterine development of the musculoskeletal system and cardiovascular system, as well as mental underdevelopment of the baby;
  • impaired blood flow in the placenta and hypoxia;
  • thrombophilia;
  • eclampsia - a sharp increase in blood pressure, accompanied by loss of consciousness, convulsive syndrome and even coma;
  • development of diabetes mellitus;
  • weakness and incoordination of labor, which entails ruptures in the perineal area;
  • the formation of stretch marks on the abdomen and chest.

A prolonged period of magnesium deficiency in the mother increases the risk of sudden neonatal death (SIDS).

Analogues of Magnelis B6

There are other medications on the pharmaceutical market designed to compensate for magnesium deficiency in pregnant women.

Drug substitutes - table

NameDosage formActive ingredientContraindicationsUse during pregnancyPrice
Magnesium pluseffervescent tablets
  • magnesium carbonate;
  • magnesium lactate;
  • vitamin B6;
  • vitamin B12;
  • folic acid.
  • severe renal failure;
  • intolerance to components.
as prescribed by a doctorfrom 148 rubles
Magne B6
  • pills;
  • solution.
  • magnesium lactate dihydrate;
  • pyridoxine hydrochloride;
  • magnesium pidolate (only in solution).
Are common:
  • severe form of renal failure;
  • phenylketonuria;
  • glucose-galactose malabsorption syndrome;
  • simultaneous use of levodopa;
  • intolerance to components.

For tablets:

  • fructose intolerance;
  • sucrase-isomaltase deficiency.
as prescribed by a doctorfrom 574 rubles
Magne B6 fortepills
  • magnesium citrate;
  • pyridoxine hydrochloride.
  • intolerance to components;
  • severe renal failure;
  • phenylketonuria;
  • hereditary galactosemia, glucose and galactose malabsorption syndrome;
  • concomitant use of levodopa.
as prescribed by a doctorfrom 536 rubles
Magnistadpills
  • magnesium lactate dihydrate;
  • pyridoxine hydrochloride.
  • hypersensitivity to components;
  • severe renal failure;
  • phenylketonuria;
  • lactase deficiency;
  • lactose intolerance;
  • glucose-galactose malabsorption.
as prescribed by a doctorfrom 238 rubles
Magwitcapsules
  • magnesium citrate;
  • pyridoxine hydrochloride.
  • intolerance to components;
  • severe renal failure;
  • phenylketonuria.
as prescribed by a doctorfrom 355 rubles
Magnesium sulfate
  • solution in ampoules;
  • powder for suspension.
magnesium sulfateAre common:
  • severe renal failure in chronic form;
  • intolerance to the active substance.

For powder:

  • appendicitis;
  • rectal bleeding;
  • intestinal obstruction;
  • dehydration (dehydration of the body).

For solution:

  • arterial hypotension;
  • depression of the respiratory center;
  • severe bradycardia;
  • AV block;
  • prenatal period.
as prescribed by a doctorfrom 50 rubles

How does magnesium deficiency manifest during pregnancy?

If the daily requirement for magnesium is not met, a deficiency of this useful element occurs in the female body. Such a deficiency poses a serious threat to mother and child and leads to the following unpleasant consequences:

  • decreased body temperature;
  • high excitability, irritability, tendency to depression;
  • worry and anxiety;
  • sleep problems;
  • swelling;
  • tingling, cramps in the muscles of the lower extremities;
  • hypo- or hypertension;
  • tingling in the heart, arrhythmia;
  • headaches, dizziness;
  • loss of appetite, nausea or vomiting (in addition to toxicosis);
  • nagging pain in the lumbar region and lower abdomen;
  • hypertonicity of the uterus, fraught with miscarriage;
  • development of gestosis (complications in late pregnancy);
  • risk of fetoplacental insufficiency.

Why do pregnant women need magnesium and vitamin B6?

During pregnancy, magnesium performs the following list of actions:

  • takes part in the metabolism and transport of nerve impulses;
  • improves the contractile capabilities of muscle fibers;
  • forms the structural basis of body tissues;
  • eliminates muscle spasms;
  • normalizes blood pressure;
  • is a source of energy;
  • preserves the viability of the fetus during early pregnancy.

Vitamin B6 has other beneficial properties:

  • improves the absorption of magnesium by the body;
  • accelerates glucose absorption;
  • normalizes metabolic processes at the cellular level;
  • stabilizes stress resistance;
  • helps overcome mental and physical stress;
  • creates favorable conditions for pregnancy.

Mechanism of action: how does B6 affect the human body

The mechanism of influence of B6 on the human body is associated with the synthesis of serotonin, the hormone of joy that regulates a person’s mood and psychological sensations. A lack of vitamin leads to depressive states and disorders of the nervous system, leading to a number of negative changes in organs.

Vitamin B6 is involved in the synthesis of a number of vital substances:

  • squirrel;
  • enzymes that regulate immune functions and a number of chemical reactions;
  • promotes the production of histamine and hemoglobin;
  • provides sufficient amounts of glutamic acid;
  • regulates lipid levels and reduces cholesterol levels (lipotropic effect);
  • improves the condition of the heart muscles, normalizes the muscular system;
  • regulates the production of folic acid;
  • has an antioxidant effect;
  • regulates skin balance.

The most important property of vitamin B6 is stimulation of the synthesis of neurotransmitters, regulation of the uptake of glucose by cells of the nervous system.

Requirement for vitamin B6

Recommended daily intake of B6:

  • for adults – up to 2.2 mg;
  • for pregnant women – up to 2.4 mg;
  • for women breastfeeding – up to 2.6 mm;
  • for children – up to 1.6 mg;
  • For children under one year of age, the dose does not exceed 0.6 mg.

General recommendations for use of the drug

The exact dosage and duration of treatment can only be prescribed by a specialist after studying the blood tests of the pregnant woman. Self-adjustment of the dose is contraindicated.

Rules for using Magnelis B6:

  • the daily dose of the drug should not exceed six to eight tablets;
  • frequency of administration - 2 - 3 times a day;
  • The tablets should be taken during meals with sufficient liquid.

As a rule, drug therapy with magnesium preparations lasts one to two weeks, then parallel intake of calcium preparations is prescribed

In this case, it is important to maintain the ratio of magnesium and calcium - 2:1

Drug interactions

If it is necessary to use different drugs in parallel, the following features of their interaction must be taken into account:

  • medications containing phosphates or calcium salts reduce the degree of magnesium absorption;
  • magnesium reduces the effectiveness of iron-containing drugs, thrombolytics and tetracycline.

The interval between taking these medications should be at least three hours.

Magnelis B6 – gynecologist’s recommendation for maternal health and pregnancy preservation

Most often, to compensate for the deficiency of vitamins and microelements, the proper development of the fetus, the gynecologist prescribes to a pregnant woman at the first consultation:

  1. Folic acid.
  2. Vitamin B6.
  3. Vitamin B1.
  4. Vitamin C.
  5. Magnesium.

If a woman is still at the stage of preparation for pregnancy, then these drugs are recommended by a doctor for preventive use.

In most cases, the gynecologist prescribes the well-known and quite popular Magne B6, the use of which is allowed from 5-6 weeks of pregnancy. Few people know that this imported product has an equally high-quality domestically produced analogue called Magnelis B6. This drug costs much less than foreign ones, and at the same time it is designed to solve a variety of problems that often arise during pregnancy. Magnelis B6 is effective in cases of threatened miscarriage, increased uterine tone, problems with the nervous system, late toxicosis, for calming, relaxing, and lifting the mood of a pregnant woman.

Adverse reactions

According to statistics, the drug Magnelis B6 is absorbed and tolerated in a fairly mild form. Adverse reactions of the body may occur in the presence of hypersensitivity to the main components of the drug in question when used during therapeutic treatment. Side effects include the following:

  1. the appearance of abdominal pain;
  2. gas formation and bloating of the anterior abdominal wall;
  3. disruption of digestive processes, accompanied by nausea, and sometimes vomiting, as well as constipation;
  4. rashes on the surface of the skin of an allergic type and the occurrence of unpleasant itching;
  5. the appearance of urticaria.

Regimen and duration of treatment

As mentioned above, the dosage and duration of administration are prescribed only by the attending physician. Independent use of the drug by pregnant women at any stage of gestation is not allowed without prior consultation with their doctor.

Only after a complete examination of the pregnant woman’s condition, clarification of possible pathologies, deviations in the functionality of other systemic organs of the female body, assessment of the baby’s development process, muscle tone of the uterus, can the doctor prescribe the drug and decide how long to take Magnelis B6.

On average, during pregnancy, doctors prescribe a dosage regimen that includes twice or three daily use of 1-2 tablets at a time during meals. Only a doctor can answer the question about how long to take Magnelis B6. Since the drug has a positive effect on the female body, helps eliminate toxicosis, improve blood circulation, normalize the tone of the uterus and the metabolic process in the body, has a general strengthening effect on the immunity of the mother and the unborn child, it is often taken until the birth is resolved.

Release forms

Magnelis-B6 is available in tablet form. The composition includes 0.47 g of magnesium salt (lactate), which is equivalent to 47 mg of elemental Mg, and 0.005 g of pyridoxine. Sucrose, kaolin, povidone and other substances are used as a base.

Magnelis B6 Forte is also on sale, a feature of which is the presence of magnesium citrate salt in its composition. The list of drugs that can replace Magnelis includes more than 30 items, but the following drugs fully correspond in composition:

  • Magnistad (“Stada”, Germany);
  • Magne-B6 (Sanofi, France);
  • Magnemax (“Health”, Ukraine);
  • Magwit (GlaxoSmithKline, Poland).

You can buy Magnelis or its cheap analogues in a pharmacy without a prescription and at an affordable price, but before starting treatment it is better to consult a specialist.

See also:

Preparations and foods rich in potassium and magnesium for the heart

Admission during pregnancy

Instructions for use for Magnelis B6 recommend taking the medicine during pregnancy only if it is prescribed by a doctor

This is due to the fact that you need to take it very carefully and at the same time carefully monitor your well-being.

It is logical that after seeing such a warning in the instructions, the expectant mother may get scared: what if Magnelis B6 may turn out to be dangerous and it is better not to take risks, even if a doctor prescribes it? But in reality there is no reason to worry. Neither magnesium nor vitamin B6 can have any negative effect on the fetus. There is simply always the possibility of side effects that can significantly worsen your well-being. In addition, the medicine has contraindications, which the doctor will take into account when deciding whether to prescribe the medicine.

In order to be completely calm about the safety and benefits of a medicine, you need to know well in what cases it may be very necessary, and when it is better to choose some other drug

And it is very important at all stages of pregnancy to consult with good doctors about taking any medicine, even ordinary vitamins

Indications

Listed above are some conditions that may indicate that you are deficient in magnesium and vitamin B6. They can occur in absolutely all people. But they talk about a serious deficiency, which during pregnancy could even lead to a miscarriage. Therefore, women in a special situation may be prescribed Magnelis B6 even when there are no such symptoms.

Conditions during pregnancy when it is considered advisable to take a course of Magnelis B6:

  1. Poor nutrition before or during pregnancy.
  2. Increased uterine tone.
  3. Risk of miscarriage.
  4. Miscarriage during a previous pregnancy.
  5. Presence of stressful situations.
  6. Physical or emotional exhaustion.
  7. Drawing sensation in the lower abdomen.
  8. Signs of oxygen starvation in the fetus.

The conditions listed above can be very dangerous for a child. But of course, the main indicator is the level of magnesium in the blood. If a deficiency is actually present, it is better not to refuse the medicine, because this will increase the chances of giving birth to a healthy baby and on time.

Contraindications

Magnelis B6 has contraindications, which are especially important to consider during pregnancy. You can usually read them in the instructions for the drug

You should not take Magnelis B6 in the following cases:

Allergy symptoms appeared while taking the medicine.

It is known that there is individual sensitivity to one of the components that make up the medicine.

Severe renal impairment

But caution must be exercised even when the problems are minor, since metabolic products are excreted through the kidneys. Any malfunction in their operation increases the risk of poisoning. Phenylketonuria. Liver failure. Lactation period

The drug passes into breast milk in large quantities, and is contraindicated for children under 6 years of age. Therefore, if a woman becomes pregnant while still breastfeeding, she needs to choose another drug or temporarily transfer the child to artificial nutrition.

Dose selection

The dosage of the drug is selected individually depending on the severity of the deficiency of magnesium and vitamin B6 and the body’s response to the drug.
It is advisable to monitor blood tests during treatment so as not to exceed the norm. The average dose prescribed to pregnant women is 2 tablets three times a day. After taking the medicine, drink it with water. But these are average figures; the doctor may prescribe a dose a little more or less. You should definitely stick to it if there are no side effects. If they appear, this may indicate that the dosage needs to be reduced.

Under no circumstances should you ignore unwanted symptoms. Usually, when a woman feels unwell, the fetus also suffers. For example, if magnesium poisoning occurs due to problems with the liver or kidneys. For this reason, it is strictly forbidden to start taking the medicine on your own.

The duration of the course of treatment is also selected for each woman separately. Most often it lasts several weeks. But there are cases when the medicine has to be taken throughout pregnancy, but with regular breaks for at least 2 weeks.

The best option is to compensate for the deficiency of the most important macroelements and vitamins at the stage of maternity planning. But if this fails, no need to worry. If you cooperate with a good specialist and pay attention to your health, there should not be any problems that would be difficult to solve.

Indications for use of the drug

  • magnesium, which is the main component of the drug, adds energy;
  • vitamin B6 improves the absorption of glucose by the body;
  • magnesium has a spasmodic effect;
  • lack of magnesium can lead to arrhythmia, headaches, spasms;
  • magnesium prevents irritability, eliminates insomnia;
  • Vitamin B6 promotes the absorption of magnesium.

These vitamins are prescribed when there is a threat of miscarriage

The main reason why Magnelis is prescribed to most women in the early stages of pregnancy is uterine hypertonicity. This prescription is 100% made for serious indications from the 5th week, if there is a threat of losing the child, and from the 13th week the drug is prescribed to everyone for preventive purposes.

The attending physician decides how long to drink Magnelis during pregnancy, but, as a rule, a similar drug is prescribed until childbirth.

Advantages and disadvantages of the product

BehindAgainst
Improved sleepNot allowed to be taken with tablets containing iron and calcium
Reduced excitability, nervousnessDiabetes
Increase in magnesium in the bodyFructose intolerance
Painkiller, one of the few allowed during pregnancy

Medical workers know the composition of the drug very well, so they will not prescribe it together with incompatible drugs, and the positive effect is much higher when using Magnelis B6. In addition, doctors' reviews of these tablets are only positive, since they monitor the development of the fetus during pregnancy.

Also read the instructions for Oscillococcinum during pregnancy and reviews of pregnant women about Pentoxifylline.

Some gynecologists prescribe Magne B6 during pregnancy, which contains the same components as Magnelis B6. Many women, having read the composition of Magnelis B6, understand that its price is significantly lower than a similar foreign drug. At the same time, there is a saving of money that can be spent on purchasing the necessary natural vegetables and fruits.

Instructions for use

Don't self-medicate

The medicine can cause allergic reactions, which often go away on their own even without stopping the drug, but if the reaction to the pills is negative and does not disappear, then immediate consultation with a doctor is necessary.

Only qualified doctors in the antenatal clinic can diagnose uterine tone, and with such indications, the expectant mother is admitted to the hospital for preservation, where Magnelis B6 is prescribed from the first day during pregnancy. During the first few days, the attending physician examines the patient daily for allergies.

Recommended in the early stages for uterine hypertonicity

Doctors rarely notice any problems, but the description says that when taking Magnelis B6 during pregnancy, there is the possibility of a number of negative aspects:

  • pain in the abdominal area;
  • constipation;
  • nausea, vomiting;
  • bloating, constant release of gases;
  • allergy.

Therefore, during inpatient treatment, it is necessary to immediately tell the medical staff about the occurrence of side effects after starting to take Magnelis B6 during pregnancy. Then the medicine will be replaced with an analogue that can compensate for the loss of magnesium in the body.

According to reviews from new mothers, many were prescribed Magnelis B6 during pregnancy and promptly warned that the tablet should be washed down with a full glass of water. In this case, the drug is quickly absorbed and causes less discomfort in terms of consequences.

According to the observation of many gynecologists, women who bought a pack of pills before childbirth continue to take them after, to relieve fatigue and irritability. But Magnelis B6 is only good during pregnancy.

You should not drink this remedy after childbirth, since after the baby is born, it quickly passes into the mother’s milk and is passed on to the baby. The instructions indicate that the age at which the drug should be prescribed is 6 years. Based on this, Magnelis can only be taken during pregnancy, and during breastfeeding it is strictly prohibited.

If there is a need to calm frayed nerves from round-the-clock communication with a newborn, you need to find products in pharmacies that do not pass into mother’s milk.

Women's opinion

According to reviews of women who took Magnelis B6 during pregnancy, it is clear that the tablets help.

Valentina Koryakova:

Irina Ivanova:

Alevtina Kulago:

Also find out the whole truth about Tantum Verde in the 1st, 2nd, 3rd trimester of pregnancy and Faringosept in the early stages of pregnancy.

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