Video Drug Magnerot
Magnerot is a common medication used in combination with other medications to treat various diseases that are associated with magnesium deficiency in the body.
Magnerot has the following actions: antiarrhythmic, antispasmodic, antiplatelet.
Magnesium is a necessary vital element in the body, which is involved in the metabolism of carbohydrates, proteins and fats, and also takes part in energy processes. Thanks to magnesium, normal myocardial function is stimulated and is also involved in the regulation of the contractile functions of the heart muscle (myocardium). With the help of Magnerot, the body becomes more resistant to stressful conditions. This drug contains orotic acid, which is directly involved in cell growth and metabolic processes. A worthy replacement for this can be its analogues, of which, as you know, there is a wide variety. Magnerot should be used after thoroughly studying the instructions and consulting with your doctor.
The main indications for use may be complex and preventive treatment of diseases of arrhythmia, chronic heart failure, dyslipidemia, atherosclerosis, diseases of the biliary tract and the vital organ of the liver, recovery processes after childbirth, etc. The drug Magnerot is very effective when used during pregnancy, as it replenishes the increased deficiencies of magnesium in the body
Also, Magnerot during pregnancy has a positive effect on malformations, various chromosomal abnormalities and is capable of preventing embryonic edema
The drug Magnerot is very effective when used during pregnancy, as it replenishes the increased deficiencies of magnesium in the body. Also, Magnerot during pregnancy has a positive effect on developmental defects, various chromosomal abnormalities and is capable of preventing embryonic edema.
It should be noted that the drug also has contraindications that should be paid attention to. These include various functional disorders of the kidneys, cirrhosis of the liver, urolithiasis, hypersensitivity to orotic acid or other substances included in the drug, hypocalcemia and others
Magnerot: use during pregnancy
Magnesium is an essential intracellular element. Its participation is considered mandatory in enzymatic reactions, neuromuscular impulses, as well as in the regulation of cellular metabolism.
Magnesium has a sedative, anticonvulsant, relaxing and analgesic effect on the nervous system, and also increases coronary blood flow. Being a salt of orotic acid, magnesium stimulates the regeneration process, normalizes metabolic reactions, and reduces the peripheral support of blood vessels.
Given the importance of magnesium in the body, it is necessary to ensure a sufficient supply of this mineral in a woman’s blood. In conditions of its deficiency, intrauterine development of the fetus is disrupted, gastrointestinal disorders appear, and smooth muscle tone increases. In addition, the risk of developing eclampsia, malformations and miscarriage greatly increases.
Magnerot is a drug with a unique composition of orotic acid derivatives, which quickly eliminate magnesium deficiency, positively affecting the course of pregnancy. Thanks to its use, it is possible to prevent hypertension, premature birth, cramps of the calf muscles, and intrauterine growth retardation.
On a note! Taking Magnerot during pregnancy has a positive effect on the emotional state of a woman and also supports the functioning of the heart muscle.
Which is better Magnerot or Magne B6
"Magne B6" is considered a direct analogue of "Magnerot", both drugs have a similar spectrum of action, but differ in structure.
The Magnerot preparation contains only magnesium compounds, and Magne B6, in addition to it, also contains vitamin B6 (pyridoxine). Both medications are intended to compensate for magnesium deficiency in the human body, especially when the deficiency of this element increases:
- in stressful situations;
- during physical and mental stress;
- during the period of bearing a child.
Magne B6 is not a cheap analogue of Magnerot. If there is a need to prevent magnesium deficiency during times of increased need for it, then either of the two medications can be given preference. Both drugs help eliminate:
- calf night cramps;
- muscle spasms;
- increased excitability;
- nervousness;
- premenstrual syndrome.
If there is a need to take magnesium to eliminate heart disease, a persistent increase in blood pressure, migraines, increased sweating, numbness of the extremities, then it is better to opt for the drug Magnerot, since this medicine is suitable specifically for the treatment of cardiovascular disorders.
The following medications are considered cheaper Russian analogues of Magnerot:
- "Vitrum Mag."
- "Magnelis B6".
- "Magnesium plus B6".
"Vitrum Mag" is a combined medication that regulates calcium metabolism. Replenishes the deficiency and corrects the exchange of Ca and magnesium. Takes part in the creation of bone tissue, conduction of nerve impulses and maintenance of myocardial function. Replenishes energy metabolism, normalizes blood clotting and muscle contractility. Magnesium increases calcium absorption and prevents the formation of calcium oxalate stones. The cost of the drug is approximately from 370 to 480 rubles.
List of cheap analogues of Magnerot:
- “Asparkam” is a Ukrainian-made drug that replenishes the lack of magnesium in the body. The cost of the medicine varies from 50 to 130 rubles. Available in the form of tablets and solution for injection.
- "Panangin" - available in tablet form, used for heart failure, as well as after myocardial infarction. The drug also increases the effect of glycosides. The price of “Panangin” (60 tablets) is 370 rubles.
- "Magvit" - a Belarusian-made medicine is one of the cheap analogues of "Magnerot". The drug helps eliminate sleep problems, relieves anxiety and seizures. Produced in capsule form. The cost of Magvit is from 200 to 230 rubles (30 tablets).
About the drug
Magnerot belongs to the group of mineral supplements. It contains magnesium and is intended to replenish its reserves in the body. The bioavailability of the drug is approximately 40%.
In the presence of severe magnesium deficiency, the level of absorption increases. With an excess of macronutrients, most of the active substances are excreted unchanged through the kidneys.
Release form
The drug is available in the form of tablets for oral administration. They have a round shape and white color, packaged in blisters of 10 pieces.
Compound
The active component of the composition is magnesium orotate. Additional components include:
- talc;
- colloidal silica;
- cellulose gum;
- maize starch;
- cellulose.
What is it prescribed for?
Magnerot is prescribed for the treatment and prevention of magnesium deficiency. When there is a shortage of this mineral in the body, symptoms such as pressure surges, muscle cramps, headaches, dizziness, and heart pain occur. Magnerot is prescribed for diagnosed magnesium deficiency and conditions associated with hypomagnesemia:
- angina pectoris;
- risk of heart attack;
- vasospasm;
- muscle cramps;
- increased irritability;
- risks of gestosis;
- violation of fat metabolism;
- atherosclerosis.
Doctors often prescribe Magnerot to pregnant women for headaches. This is explained by its positive effect on blood vessels and blood supply to the brain. The drug helps eliminate migraine attacks characteristic of the gestational period.
Magnerot during pregnancy and breastfeeding
Considering the fact that many women during pregnancy are faced with uterine hypertonicity and the threat of fetal loss, as well as cramps of the calf muscles and palpitations, gynecologists widely use Magnerot in clinical practice. The drug is most often prescribed for the threat of miscarriage, for hypertonicity of the uterus, for gestosis with edema, for fetal hypoxia and for unpleasant pulling sensations in the lower abdomen and lower back. Magnerot quickly and effectively relieves these symptoms, allowing a woman to bear a fetus and not suffer from discomfort during pregnancy.
In addition, Magnerot is prescribed for surges in blood pressure, hypertension, tachycardia, pain in the heart and calf muscle cramps, as well as a high risk of preeclampsia, which develops in some pregnant women in the second trimester.
The drug is also actively used by gynecologists to eliminate increased excitability and nervousness in pregnant women. If these symptoms are present, Magnerot acts like a sedative without causing any harm to the woman or fetus.
Considering the benefits of Magnerot, as well as the wide and varied range of conditions for which its use is indicated, gynecologists often prescribe the drug in long courses throughout pregnancy. Some pregnant women take Magnerot during the entire period of pregnancy, discontinuing it only after the 36th week of gestation. Others take the drug for 2–4 courses with short breaks between them.
Gynecologists recommend that pregnant women take Magnerot according to the following scheme: in the first week, drink 2 tablets 3 times a day, then for a month drink 1 tablet 3 times a day. After this, you can take a 2-4 week break from taking Magnerot or continue taking the drug, but 1 tablet once a day for an unlimited time (usually until the 36th week of pregnancy).
To prevent an overdose of Magnerot, it is recommended to periodically (once every 2-3 weeks) take a blood test to determine the concentration of magnesium in the blood. If this is within the normal range, then the drug can be continued to be taken. If the concentration of magnesium in the blood is at or above the upper limit of normal, then you should stop taking Magnerot for at least 3 weeks. The normal concentration of magnesium in the blood of a pregnant woman is 0.66 - 1.07 mmol/l.
If, while taking Magnerot, a pregnant woman suffers from abdominal pain, unstable stools or diarrhea, then the dosage of the drug should be reduced and continued so that the total duration of use is at least 4 - 6 weeks.
Magnerot user reviews
I didn’t expect it, but after three days of taking it, I felt relief. My convulsions stopped. I began to sleep better every night. A week later, when measuring the pulse, it began to return to normal. It was a wonderful transformation; no examinations or expensive drugs were needed. There just wasn't enough magnesium!
Within two weeks the pulse was completely normal. I stopped being nervous about my colleagues and other various factors. The nervous system has recovered.
Therefore, I am very pleased with Magnerot. The only sad thing is that when prescribing contraceptives, the doctor did not warn about a decrease in the amount of magnesium.
pharmachologic effect
Pharmacodynamics
Magnerot helps increase the amount of magnesium. When a deficiency of this macronutrient occurs within the body, the following occurs:
- neuromuscular disorders, which manifest themselves in increased excitability (sensory, motor), the appearance of seizures, paresthesia;
- deterioration of the cardiovascular system (ventricular extrasystole, tachycardia, increased sensitivity to cardiac glycosides);
- psychological changes (confusion appears, depression begins, hallucinations may occur).
In pregnant women, a lack of magnesium provokes toxicosis and can cause premature birth.
"Magnerot" is a magnesium preparation. This element is involved in carbohydrate, lipid, protein, and energy metabolism. It is also involved in the exchange of nucleic acids and in the regulation of neuromuscular excitation. It is a universal regulator of physiological and biochemical processes in the human body.
Role of Components
The role of magnesium is:
- fixation of macronutrients inside cells;
- regulation of myocardial contractions;
- regulation of metabolism;
- maintaining the work of cardiomyocytes;
- increasing the body's resistance to stress;
- stimulating cell growth (thanks to the drug orotic acid).
Functions of orotic acid salts:
- participation in metabolism;
- fixation of the microelement on ATP inside the cell;
- manifestation of the effect of magnesium.
Considering the functions of the main components of the medicine, its action is as follows:
- restoration of magnesium levels;
- providing an antispasmodic effect. It is able to relieve spasms and tics;
- improving metabolism;
- providing an antiarrhythmic effect. It ensures the correct activity of the heart muscle;
- manifestation of antiaggregation action. The drug reduces the intensity of thrombus formation.
Pharmacokinetics
- The body receives only 35-40% of the amount of medication taken.
- Magnesium absorption is activated by hypomagnesemia. Orotic acid is needed for more efficient absorption of the microelement.
- Magnesium is excreted from the body through the kidneys.
Read below about the indications for use of the drug Magnerot, as well as about possible use during pregnancy.
Magnerot reviews from cardiologists
Doctors, it turns out, often use the drug. When I told the cardiologist that I was taking Magnerot, she approved of my choice. She said that she was also going to prescribe it for me after the examination was completed.
“Magnerot is a drug that improves heart rate. Usually prescribed to people with various forms of arrhythmia, as well as sinus tachycardia. The trace element helps to achieve complete relaxation of the heart muscle and a stronger contraction, which promotes good blood expulsion. Metabolic processes in the body improve. This is good help for heart failure,” - cardiologist Yuri Novatsky.
“Hypertension is simply the scourge of our time. Lack of movement and constant stress factors affect people's health. When fighting the disease, I prescribe not only antihypertensive drugs. It is very important to follow a routine, eat right, and also be less nervous. Magnerot is an excellent preventive and therapeutic medicine, which not only helps stabilize blood pressure, but also increases resistance to stress,” cardiologist Yulia Mikhailyuk.
“I recommend Magnerot to patients who experience a lot of stress. This element helps relieve nervous tension and allows a person to react more calmly to an unfavorable environment. It is especially important for heart patients and elderly people to take the drug. Timely intake of magnesium can eliminate the need to drink nitroglycerin or validol in the future,” cardiologist Irina Podvysotskaya.
Drug price
- Magnerot, 20 tablets – 235 – 338 rubles;
- Magnerot, 50 tablets – 525 – 677 rubles.
Before use, you should consult a specialist.
"Magnerot" is a drug that can restore the balance of magnesium in the human body. A lack of this microelement can provoke the appearance of various heart diseases, so this remedy is prescribed to patients with problems of the cardiac system. In addition, this medication can calm neuromuscular overexcitation and reduce susceptibility to stressful situations. Today we will find out how to take Magnerot tablets, what their price is, and also find out the opinions of patients and doctors about the effectiveness and safety of this drug.
Can pregnant women take it?
Magnesium deficiency in a pregnant woman can lead to dangerous consequences. These include the risks of miscarriage and premature birth, as well as anomalies and malformations in the fetus. In addition, a lack of the mineral leads to stressful conditions that are extremely undesirable for the expectant mother. Therefore, if there is a confirmed deficiency of a component, the doctor may prescribe Magnerot. The drug is well tolerated and rarely causes adverse reactions.
In 1st trimester
In the first trimester, the fetus is just beginning to form. Its organs and systems are being formed, and in order for these processes to occur correctly, the expectant mother’s body must have enough useful substances. With a lack of magnesium, abnormal development of the embryo is possible, so the doctor may prescribe Magnerot.
In the 2nd trimester
At this time, the fetus has already formed to a certain extent and continues to actively develop. A lack of magnesium in a pregnant woman’s body is fraught with negative consequences, both for the unborn child and for the expectant mother herself, who faces headaches, irritability and other unpleasant symptoms. The doctor may decide to prescribe Magnerot if a deficiency of the mineral is confirmed by research.
During the 3rd gestation period
In later stages, Magnerot is often prescribed if there are signs of gestosis. It is also necessary for hypertonicity - the drug helps relieve spasms of smooth muscles and reduce the risk of miscarriage. Sometimes prescribing medication to a pregnant woman in the third trimester is not associated with pregnancy problems. Thus, it can be indicated for diseases of the cardiovascular system. The drug helps normalize heart rhythm and prevent pressure surges.
Domestic analogues
Magnelis B6 is a slightly more expensive generic Magnerot, which contains two active components: magnesium and vitamin B6. The drug is prescribed for a deficiency of this element. The average duration of treatment is no more than thirty days
Caution should be exercised if you have diabetes, as the tablets contain sucrose. Prohibited for patients with renal failure, under the age of 6 years only as prescribed by a doctor.
Approved for use during pregnancy. Side effects manifest themselves in the form of nausea, vomiting, allergic reactions. The cost of the drug varies from 250 to 330 rubles. "Magnelis B6" is one of the cheap analogues of "Magnerot".
"Magnesium plus B6" is a complex medicine based on B vitamins in combination with mineral trace elements. The drug is available in the form of white effervescent tablets. The medicine has a slight specific odor. Sold in tubes of ten pieces. The active components of this drug are multivitamins and mineral salts.
"Magnesium plus B6" is used during pregnancy only as prescribed by a doctor. Magnesium passes into breast milk, so it is necessary to avoid taking the drug during lactation. The cost of the drug varies from 310 to 450 rubles.
Analogs
Medicines containing magnesium and a similar therapeutic effect can replace the drug. These include:
- Asparkam – solution and tablets containing potassium and magnesium aspartate;
- Panangin – tablets and concentrate for solution based on potassium and magnesium aspartate;
- Megamag - capsules, whose composition contains magnesium aspartate dihydrate, eliminate magnesium deficiency.
Magnerot or Magne B6 – which is better?
The popular analogue of Magnerot Magne B6 contains magnesium salts of lactic, citric and pyroglutamic acid and an additional ingredient - vitamin B6, produced by the French company Saofi in the form of tablets and oral solution. There is 0.47 g of magnesium lactate per tablet, and 0.618 g of magnesium citrate in the Forte version. Magne B6 is better absorbed by the body, but can be used during pregnancy only if necessary.
Magnerot or Magnelis - which is better?
The second known analogue of Magnerot - Magnelis - contains magnesium lactate and vitamin B6, which improves the absorption of the mineral. One Magnelis tablet contains 48 mg of magnesium versus 32.8 in Magnerot. Unlike the remedy in question, Magnelis cannot be used to treat heart disease, because it is intended only to compensate for the deficiency of the element. The advantage of Magnelis is that it can be taken by children over six years of age, but it is not recommended for use during pregnancy.
Magnerot or Magne B6
If you need to take a drug to prevent or eliminate magnesium deficiency during periods of increased need for it, then you can choose any remedy - Magnerot or Magne B6, depending on which one you like best for subjective reasons, since in this situation their effect is practically the same.
You can also choose any drug based solely on personal preference to treat calf cramps, muscle spasms, excessive excitability, nervousness and discomfort during PMS.
However, if it is necessary to take the drug to eliminate cardiac disorders, arterial hypertension or neurovegetative symptoms (dizziness, headaches, hot flashes, sweating, irritability, numbness of the limbs, crawling sensation, etc.), then in this case it is better to prefer Magnerot, since this drug, unlike Magne B6, has a “cardiac” action.
In addition, if it is necessary to give magnesium preparations to children, it is recommended to prefer Magne B6 in the form of an oral solution, since this dosage form is optimally suited for young patients and is officially approved for use.
List of drugs
The drug magnesium orotate dihydrate can be purchased in the form of tablets with a standard content of active substance of 200 or 500 mg. It is usually presented in the form of mono-supplements.
KAL – Magnesium orotate
KAL, Magnesium Orotate, 200 mg, 60 tablets
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592 rub.
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General information:
- Country: USA;
- concentration – 200 mg (mg);
- volume – 60 tablets.
The dietary supplement is made using ActivTab technology, which guarantees complete release and absorption of the active compound in 30 minutes. Adults need to take this drug 2 tablets per day with meals.
Magnerot
Magnerot tab. 500 mg No. 50
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General characteristics:
- country of origin – Germany;
- element concentration – 500 mg;
- package volume – 50 tablets.
The drug contains magnesium orotate dihydrate. Tablets are taken not only to replenish mineral deficiency, but also for complex treatment of ischemic heart disease, lipid metabolism disorders, and arteritis. Regimen for taking magnesium dihydrate: in the first week, 2 tablets 3 times a day, then 1 tablet. 2-3 times a day.
There is a packaging variation that contains 20 tablets:
Magnerot tab. 500mg n20
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Magnemax
Magnemax tab. 500 mg No. 20
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Characteristics of the drug:
- country Russia;
- substance concentration – 500 mg;
- volume – 20 tablets.
The Russian analogue contains a high concentration of the element and quickly replenishes magnesium deficiency in the body. The instructions for use indicate that you need to take 1 tablet. 2-3 times a day and should not be taken by children.
Pharmacological properties
The drug has antiarrhythmic, antiplatelet and antispasmodic effects. The main active component is magnesium orotate dihydrate. Thanks to magnesium, many energy processes occur and metabolism occurs in the body. The element participates in the processes of neuromuscular excitation, simultaneously inhibiting neuromuscular transmission. Its biological effect is opposite to the work of calcium, which determines its use as a natural biological antagonist of this substance. Magnesium normalizes the functioning of the heart muscle and is involved in the regulation of its contractility. The use of the drug "Magnerot" allows you to increase the body's resistance to stress, since in these situations there is an increased excretion of magnesium. The orotic acid included in the composition stimulates cell development, takes part in metabolism, helps magnesium fix in cells and manifest its properties.
Composition and effect of components
In general, magnesium is a vital macronutrient. It is constantly present in the body and is consumed a lot. The compound is involved in more than three hundred biochemical processes. Therefore, a lack of magnesium inevitably leads to illness.
One of the main purposes of the compound is to participate in the regulation of muscle function. Magnesium is an element that forms the relaxation impulse. It works in conjunction with calcium, which provokes an increase in tone and contraction. Magnesium has a particular effect on the heart muscle, intestines, uterus, and, in general, the smooth muscles lining the organs. By the way, blood vessels also have a muscle layer, so magnesium is important for reducing blood pressure.
It relieves tension, pain caused by muscle spasms, and relaxes the arteries.
Magnesium has a positive effect on the nervous system. Here it plays the role of a calming component that inhibits overexcitation. It is part of the neurotransmitters through which nerve cells transmit signals to each other.
The compound is necessary to provide the cell with energy, since it is involved in the breakdown of ATP. Provides the element of protein production for the internal needs of the body. It is also necessary for good growth of young cells and regeneration processes.
The element is part of muscles and bones. Without it, potassium and sodium and B vitamins cannot be absorbed normally.
What else does magnesium depend on?
- Regular bowel movements - it improves intestinal function, moving food mass to the exit.
- Treatment of biliary dyskinesia. It is associated with spasm of the sphincter and the channels through which bile enters the intestines. Improving the secretion of bile normalizes digestion, removes nausea and heaviness.
- Memory. Magnesium is involved in the process of memorization and the functioning of the nervous system. A sufficient amount of it protects against the development of dementia.
- Bone growth. Even as adults, our bones are constantly renewing and mineralizing or losing minerals. In the latter case, osteoporosis develops, a disorder of the bone heads entering the joints. Magnesium prevents these diseases.
- Fighting stress. A person taking Magnerot tolerates stress better.
In combination with orotic acid, magnesium is better absorbed. Moreover, everything in the body is arranged in an amazing way; if there is not enough magnesium, more of it is absorbed from the drug.
This microelement is especially needed if you take contraceptives, diuretics, inject insulin, or take glucocorticoids for inflammation. These drugs reduce the amount of magnesium in the body, even if you get enough of it with food. In this case, long-term use of Magnerot is permitted.
Magnerot for children
Thus, drug manufacturers are required to indicate a contraindication for use in children under 18 years of age if there are no results of clinical trials in which the safety and effectiveness of the drug were proven. Even if the drug has been used for many years, and clinical observations have shown that it is well tolerated by children and is safe and effective for them, the manufacturer must still indicate in the instructions that it is contraindicated for use under 18 years of age, unless clinical trials have been carried out. Thus, a situation arises where official trials have not been carried out, but practical observations have shown that the drug is safe and effective. Doctors, knowing this state of affairs, are guided by the experience of using Magnerot for children, and not by official instructions, and therefore prescribe the drug from one year onwards.
For children, the drug is often prescribed for various interruptions in the functioning of the heart that are not associated with severe heart disease. For example, adolescents often experience extrasystoles, bradycardia, tachycardia or myocardial dystrophy, due to the fact that the development of internal organs does not keep pace with the rapid growth of the body and skeleton. In such cases, Magnerot is a safe and effective drug that eliminates such manifestations of functional disorders of the heart.
In addition, Magnerot is prescribed to children of all ages who suffer from increased excitability, nervousness, a tendency to hysteria, sleep disturbances, frequent awakenings, and difficulty falling asleep. The drug eliminates these manifestations, making the child calmer, more diligent, less hot-tempered, etc.
The drug is also effective for relieving muscle spasms and cramps in children of any age. For spasms, Magnerot is prescribed as the main treatment, and for convulsions - as part of complex therapy.
Dosage
Magnerot for children over 12 years of age is the same as for adults. That is, a teenager should take 2 tablets 3 times a day during the first week, and then take 1 tablet 2-3 times a day for 4-5 weeks. The total duration of therapy is 4–6 weeks, but if necessary, can be extended for an indefinite period of time.
For children aged 1 - 12 years, the dosage of Magnerot is calculated individually according to body weight, based on the ratio of 10 - 20 mg per 1 kg of weight per day. The calculated daily dosage is divided into 2 - 3 doses per day and given to the child before meals. Let's look at dosage calculation using an example.
If the child’s body weight is 20 kg, then the daily dosage of Magnerot for him is 10 * 20 = 200 mg or 20 * 20 = 400 mg, which corresponds to approximately half or a whole tablet. It is convenient to divide this amount into two doses per day and give the child either 1/4 or 1/2 tablet 2 times a day. It should be remembered that children under 12 years of age should not be given more than 4 Magnerot tablets per day. The duration of therapy for children is 5–10 days. After 5 - 10 days, on the recommendation of a doctor, you can continue taking Magnerot in a dosage halved for another 2 - 3 weeks.
Purpose
The drug can only be recommended for use by a doctor. You cannot take the drug on your own, even if a woman notices signs characteristic of hypomagnesemia.
As a rule, the appointment is made after studying the results of a biochemical blood test, which allows one to judge the degree of deficiency of the element in the body. Carrying out such an analysis will allow you to select the optimal dosage.
Most often, pregnant women are prescribed Magnerot when hypertension is detected. Timely use of the drug can relieve spasm of smooth muscles and reduce the risk of miscarriage.
In later stages, Magnerot can be prescribed if signs of gestosis are detected. In this case, a drug containing magnesium is taken as part of complex therapy. The drug helps remove swelling, improve the supply of blood to the fetus and, accordingly, nutrients.
In some cases, the prescription of the drug to pregnant women is not associated with problems with pregnancy. This remedy can be prescribed in the presence of diseases of the cardiovascular system. Taking the drug helps normalize blood pressure and heart rhythms.
How to use?
The treatment will be quite long, the minimum course of taking the drug is one month. If the deficiency of magnesium is significant, then Magnerot can be recommended for use for several months, sometimes right up to childbirth.
The dosage regimen given in the instructions included with the drug:
- in the first week, take 1000 mg (2 tablets) three times a day;
- the next week, the drug continues to be taken three times a day, but the single dose is halved;
- starting from the third week, take 500 mg (one tablet) once a day.
Advice! After the tests, the doctor may recommend a different dosage regimen that differs from the one given in the instructions. In this case, you need to follow the recommendations of a specialist.
The instructions recommend adhering to the following rules of admission:
- You need to take the tablet whole, without crushing it;
- It is recommended to drink it with water, it is recommended to drink at least a glass;
- You need to take the tablet about an hour before meals;
- After taking the drug, it is not recommended to drink strongly brewed green or black tea, as well as coffee, for an hour. Substances contained in these drinks interfere with the absorption of magnesium.
Overdose
With normal liver function, taking Magnerot does not cause intoxication. The drug can provoke botulism in kidney and liver diseases. An overdose can occur as a result of an increased concentration of magnesium in the blood. Symptoms of poisoning:
- low blood pressure;
- nausea;
- diarrhea;
- vomit;
- depressive disorder;
- coma;
- anuria (a clinical symptom that is manifested by the complete absence of urine in the bladder and, as a consequence, the cessation of its release from the urethra).
Therapy:
- oral rehydration (re-saturation of a previously dehydrated body with water);
- detoxification method, which is based on the accelerated removal of toxins from the body by increasing the volume of urine produced.
In case of renal failure, it is necessary to use hemodialysis (a method of blood purification for acute and chronic renal failure) and peritoneal dialysis (one of the methods of blood purification that is used for impaired renal function).
Side effects
Magnerot is well tolerated by patients, sometimes causing side effects. These include digestive disorders, unstable stools, diarrhea, allergic reactions, urticaria, exanthema, papular rashes on the skin, itching, which go away on their own. With normal renal function, taking the drug does not lead to poisoning, but with renal failure this is possible. Signs appear more pronounced with increased concentrations of magnesium in the blood serum.
According to the instructions, the symptoms of a drug overdose are anuric syndrome, decreased blood pressure, cardiac arrest, nausea, coma, vomiting, slowed reflexes, and depression. Magnesium intoxication can cause obstruction of the biliary tract, paralysis of the respiratory muscles and failure of gastric or atrioventricular conduction.
Treatment consists of rehydration, forced diuresis; in case of renal failure, hemodialysis and peritoneal dialysis are indicated. To restore magnesium balance, large amounts of potassium, which is its natural antagonist, should be administered. If necessary, therapy is supplemented with resuscitation of the lungs and heart.
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Magnerot, analogues, indications for use
The closest structural analogue is the drug “Magnesium Orotate”. Medicines are prescribed for the prevention and complex treatment of chronic heart failure caused by magnesium deficiency, arrhythmia, heart attack, angina pectoris. The medicine is used for myocardial dystrophy, spastic conditions, pathological vasoconstriction caused by prolonged intense muscle contraction. The drug "Magnerot" and its analogues are used for atherosclerosis, dyslipidemia, diseases of the liver and biliary tract, increased physical activity, progressive muscular dystrophy, and for recovery after illness. It is very effective to use the medicine “Magnerot” (reviews from patients who used the drug for these indications confirm this fact) for digestive pathologies, chronic alcoholism, stress, physical inactivity and other conditions that require an increased intake of magnesium.
Contraindications
Taking magnesium is prohibited in the following conditions:
- decompensated renal failure with creatinine clearance less than 30 ml/min;
- severe atrioventricular block;
- cirrhosis of the liver;
- allergy to medication components;
- age up to 6 years.
The supplement is safe during pregnancy, but its use should be under strict medical supervision. During treatment, you need to regularly take blood tests for electrolytes.
The drug is prescribed with caution for renal diseases, as there is a risk of hypermagnesemia.
Features of the drug
Thanks to its unique combination, this product has advantages over other magnesium preparations. After all, it is orotic acid that acts as a conductor of this microelement to the cells. Magnesium is considered a natural insulator that replenishes missing dopamine.
This drug differs from other drugs in the following ways:
- The method of taking Magnerot is much more convenient than other drugs (it is used orally).
- It does not contain gluten (it can be used in the treatment of children and adolescents).
This drug is able to increase physical performance, therefore it is considered very effective in the treatment of chronic fatigue syndrome and stress. Thanks to magnesium therapy through Magnerot, resistance to hypoxia increases, magnesium deficiency is eliminated, and muscle convulsive activity is reduced. For this reason, this medicine is widely used in neurology and neuropediatrics.
Compound
The active ingredient in Magnerot is magnesium orotate dihydrate.
One tablet contains 500 mg of the main substance. The drug contains:
- corn starch;
- silicon dioxide (colloidal);
- talc;
- carmellose sodium;
- magnesium stearate;
- povidone K30;
- sodium cyclamate;
- lactose monohydrate.
Dosage forms
The medicine in question is produced in the form of tablets. Magnerot is produced in cardboard packs. The pack contains 2.5 blisters. Each blister contains 10 tablets.
The price of Magnerot in different online pharmacies varies significantly:
A drug | Pharmacy name | Price |
"Magneroth". 20 pcs. | WER.RU | 277 rub. |
"Magneroth". 20 pcs. | PHARMACY IFK | 362 rub. |
"Magneroth". 50 pcs. | WER.RU | 588 rub. |
“Magneroth. 50 pcs. | PHARMACY IFK | 641 rub. |
"Magneroth". 20 pcs. | Piluli.ru | 310 rub. |
"Magneroth". 50 pcs. | Piluli.ru | 651 rub. |
Composition and release form
Magnerot is presented in the form of tablets for oral use. They are packed in 10 pieces. in blisters; the pack contains 2–5 blisters along with instructions. Detailed composition of the medicine:
Description | White round flat tablets |
Concentration of magnesium orotate dihydrate, mg per tablet | 500 |
Additional components | Magnesium stearate, colloidal silicon dioxide, talc, sodium carmellose, sodium cyclamate, microcrystalline cellulose, lactose monohydrate, corn starch, povidone |
pharmachologic effect
Pharmacological group - magnesium-based preparations for the heart, which are sources of minerals in the body. The mechanism of action of the drug is ensured by the activity of Magnesium, which is part of the drug.
Pharmacological actions of Magnerot:
regulation of cell wall permeability; improvement of neuromuscular impulse transmission; participation in providing energy processes, stimulating the production of ATP - an important source of energy for cells throughout the body. This feature of magnesium is important, including for athletes, especially those involved in weightlifting and bodybuilding; improved metabolism
Magnesium is a participant in many metabolic reactions in the body. This property of the drug is used in sports; normalization of the work of heart muscle cells; improvement of myocardial contractility; calming effect; elimination of tachycardia; prevention of seizures; reduction of pain syndrome; elimination of spasms and decreased smooth muscle tone; decreased vascular resistance; stimulation of general blood flow; decreased amount of calcium in the blood; improving blood supply to the heart muscle; decreased release of acetylcholines; decreased platelet aggregation; accelerating the restoration of damaged tissues.
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Magnesium orotate
Average rating: Number of reviews: 0
Pros:
- the supplements have a high-quality chemical formula that is well absorbed;
- relieve cramps in the calf muscles and leg fatigue;
- eliminate muscle spasms;
- normalize mood during pregnancy and during PMS.
Minuses:
- Some customers experienced nausea after taking the pills.
Popular substitutes for Magnerot
Magnelact
Magnelact is a drug enriched with magnesium. Its composition includes magnesium lactate trihydrate, vitamin B6, as well as a huge number of auxiliary components, such as talc, polysarbate 80, sodium starch glycolate, lactose monohydrate and others.
It is usually used as an additional source of magnesium and vitamin B6. Contraindications for this drug include renal failure and individual intolerance to some components of this drug.
Magne B6
Magne B6 is the most common drug used to replenish magnesium in the body. This combination drug contains pyridoxine and magnesium. Magne B6 is prescribed mainly for preventive purposes. It is also used for severe fatigue, sleep disorders, asthenia, tingling sensations and other symptoms that are associated with a lack of magnesium in the body. You should not take Magnesium B6 if there are disturbances in the absorption of glucose and galactose, renal failure, or sucrose deficiency. Magnesium B6 is not prescribed to children under 1 year of age. In cases of long-term use of this drug, peripheral neuropathy (peripheral NS is damaged) and paresthesia (tingling sensation, crawling sensations) may occur.
Magnesium plus
This is a complex of minerals and multivitamins, the main composition of which is magnesium lactate, pyridoxine hydrochloride, cyanocobalamin, folic acid and other excipients (citric acid, aromatic additive, etc.).
It is used for magnesium deficiency, as well as for diseases arising from a lack of magnesium.
Contraindicated in patients with renal failure, individual intolerance and hypersensitivity to some components of this drug. Children should only take it from 6 years of age.
The main side effects are: allergic reactions, pain in the abdomen, diarrhea.
Magnelis B6
Magnelis B6 contains the active substance magnesium lactate and auxiliary substances - sucrose, silicon dioxide, povidone and others. It has many contraindications, such as: renal failure, hypersensitivity, phenylketonuria. Side effects include vomiting, nausea, allergic reactions, and flatulence.
Magnerot is an ideal combination of magnesium and orotic acid. Thanks to its unique combination, this product has advantages over other magnesium preparations. And today we will look at the instructions for using Magnerot, its analogues and prices, reviews about it.
Adverse reactions
Usually the drug is well tolerated. But the possibility of an allergic reaction should not be ruled out. In rare cases, the following side effects may occur:
- stool disorders;
- skin rash;
- abdominal discomfort.
If a woman has healthy kidneys, then even with an overdose of the drug there will be no negative consequences - excess magnesium will simply be excreted from the body. However, if kidney function is impaired, consequences such as vomiting, decreased blood pressure, and in severe cases, coma and cardiac arrest are possible.
For symptoms of magnesium poisoning, rehydration and diuresis are performed. In case of kidney failure, hemodialysis is additionally required.
Instructions for use of the drug Magnerot
"Magnerot" is used orally. To achieve the best effect, take the product before meals (60 minutes before). Take the tablet with water.
If the patient is taking tetracyclines, an iron supplement, or sodium fluoride, it is necessary to maintain an interval of approximately 2 hours between medications. The appropriate dosage and duration of treatment are determined by the doctor.
- Adults need to drink 2 Magnerot tablets at a time three times a day. This dosage must be observed for 1 week of treatment. In the future, 1 tablet is prescribed three times a day. On average, the course duration is 1-1.5 months.
- For children under 12 years of age, the doctor calculates the dosage individually. It should be based on the child’s weight (10-20 mg per 1 kg).
Interaction
Is it possible to combine the drug Magnerot with other drugs? The instructions for use (the price of this medicine is not very high) states that this medication must not be combined with iron salts, tetracyclines and sodium fluoride, since the intestinal reabsorption of the latter is significantly reduced.
When magnesium is used in parallel with neuroleptics, sedatives or tranquilizers, their pharmacological effect is potentiated.
When Magnerot is combined with antihypertensive and antiarrhythmic drugs, the severity of their therapeutic effect increases (the development of bradycardic or hypotensive crises is possible).
How to take Magnerot
The drug is intended for oral use. To achieve the maximum therapeutic effect, it is recommended to take the tablets 60 minutes before meals. Magnerot tablets should be taken whole with a small amount of drinking water. When used simultaneously with iron preparations, tetracyclines and sodium fluoride, it is recommended to maintain an interval of at least 2 hours between taking these drugs. The duration of therapy and dose of magnesium orotate are determined by the attending physician individually.
As a rule, 2 tablets of the drug are prescribed three times a day for 1 week, after which they switch to taking 1 tablet three times a day.
The total duration of the course of taking magnesium orotate is 1-1.5 months. If necessary, the course of treatment is repeated after some time.
Patients suffering from night cramps are usually prescribed 2-3 tablets of Magnerot once a day before bedtime. The maximum recommended daily dose of magnesium orotate dihydrate is 3000 mg (6 tablets of Magnerot).
Directions for use and dosage
According to the instructions, the tablets are taken orally before meals, washed down with water. The average dosage is two pieces three times a day for a weekly course, then one 2-3 times a day for a course of 4-6 weeks. For night cramps in the calf muscles, take 2-3 pieces. In the evening. The maximum daily dose is 300 mg of magnesium orotate or six tablets.
Article on the topic: Kipferon - instructions for use, indications, release form, composition, side effects, analogues and price
Ukrainian-made substitutes
- Asparkam. The medication helps normalize the balance of ions, not only magnesium, but also potassium. It contains two active ingredients - potassium and magnesium aspartate, 175 mg per tablet. There are also auxiliary components - calcium, starch and talc.
- Panangin. Used after myocardial infarction, for heart failure, in additional therapy to increase the effectiveness and tolerability of glycosidones. Available in both tablet and injection form. During pregnancy and breastfeeding, it is allowed to be taken exclusively in the form of injections.
- Magnemax. It has the form of two-layer tablets, consisting of a film shell and the drug itself. Sold at a fairly affordable price.
Magnerot: what is it
Magnerot is a drug that contains only one useful trace element, magnesium. It is included in the composition in the form of a compound, magnesium orotate dihydrate. The active ingredient contains 500 mg, just enough to cover the daily requirement. The remaining auxiliary ingredients are lactose, microcrystalline cellulose, silicon dioxide.
The packaging of the product is bright - completely red. No drawings. Name of the drug, composition. There are five blisters with tablets inside. They are opaque white. The tablets are also round and white with a dividing chamfer. There are 50 pieces in total in the package.
The product is produced by the German company WOERWAG PHARMA. A foreign manufacturer gave me more confidence, so of all the products presented in the pharmacy, I chose it, and also because a friend recommended it.
special instructions
Use during pregnancy and lactation.
It is possible to use the drug during pregnancy and lactation (breastfeeding) according to indications, since during these periods the need for magnesium increases significantly.
If its content is not balanced, this can lead to serious complications, incl. miscarriage.
The use of the drug during pregnancy and lactation is possible if the potential benefit to the mother outweighs the potential risk to the fetus and child.
The drug can be used for a long time.
It should be taken into account that gastrointestinal diseases can lead to magnesium deficiency in the body; consumption of foods with reduced magnesium content; playing sports (due to increased sweating); chronic alcoholism (due to decreased resorption of magnesium in the renal tubules and increased excretion of magnesium ions from the body); taking certain medications (cardiac glycosides, aminoglycoside antibiotics, oral contraceptives, diuretics, laxatives, glucocorticosteroids); conditions requiring increased magnesium intake (physical inactivity, stress, pregnancy and lactation); prolonged exposure to the sun.
Impact on the ability to drive vehicles and operate machinery.
The drug does not affect the ability to drive vehicles and other activities that require high concentration and speed of psychomotor reactions.
Pharmacodynamics and pharmacokinetics
The chemical feature of magnesium orotate is that it is metabolized disseminated, that is, the drug is absorbed in different ways. The largest amount is in a free, ionized state in the systemic bloodstream and is excreted along with urine by the kidneys. About 30 percent of magnesium salts bind to blood plasma proteins, which prolongs the presence of the drug in the body. 10-15 percent accumulates in the form of salts in bone formations or intracellular spaces, where they are included in compounds with DNA , RNA and ATP .
Orotic acid is metabolized to a greater extent in the liver. With its help, uridine monophosphate , which is then part of the intermediate synthesis of pyrimidines. Thus, the biologically active component of the drug can be excreted in three ways:
- through the intestines;
- kidneys;
- sweat glands.
It should be noted that Magnerot is a very active drug. The main active ingredient penetrates the blood-brain and placental barrier relatively easily. Magnesium orotate is also detected in breast milk during lactation.
Negative feedback from patients
The Magnerot product has not only good reviews, but also bad ones. However, there are very few negative responses. Some patients note that after taking this drug they began to have problems with bowel movements, and some developed a rash all over their body. However, to prevent this from happening, you must carefully read the instructions for the medicine so that no side effects occur. After all, symptoms such as itching, rash and diarrhea are observed due to the fact that a person takes the medication in a dose that exceeds the norm.
Also, some people are unhappy with the high cost of the drug Magnerot. However, it is difficult to do or change anything about this, since all such means are expensive.
Existing indications for use
Prevention, as well as complex treatment:
- Myocardial infarction;
- Arrhythmia (provoked by magnesium deficiency);
- Angina;
- Atherosclerosis;
- Impaired lipid metabolism;
- Spastic condition – muscle spasms and pain (including vasospasm);
- Arteritis;
- Chronic form of heart failure.
Magne B6 forte analogues
Magne B6 forte, unlike the usual form, contains another salt - citrate. The price of the product is higher. It has the same indications as the regular drug. It differs in its application characteristics - a maximum of 3-4 tablets per day, divided into 2-3 doses. It is also approved for use by pregnant women as prescribed by a doctor.
What to choose – Magne B6 or Magne B6 forte, depends on the indications. If you need to take 6–8 tablets per day, it is advisable to replace it with a strengthened formula or a cheaper analogue of Magnesium B6 forte.
Substitutes can be used in consultation with a doctor. The complete Russian analogue of Magne B6 forte is Magnelis forte .
Therapeutic effect
Magnerot has the following pharmacological effects due to the magnesium it contains:
- Replenishes magnesium deficiency in body tissues;
- Improves the metabolic process;
- Antispasmodic effect;
- Antiarrhythmic effect;
- Anti-aggregation effect.
Magnerot is able to have a positive effect on metabolism, since magnesium, which is part of it, activates more than 300 enzymes that carry out a wide range of different biochemical reactions that ensure the metabolism of fats, proteins and carbohydrates.
In addition, magnesium is necessary for the formation of a universal cellular energy molecule - ATP (adenosine triphosphoric acid), which is used as an energy source for biochemical reactions. Magnesium is also a calcium antagonist and is involved in maintaining the normal intracellular balance of this element, preventing its amount from exceeding the norm.
The antispasmodic effect of Magnerot lies in its ability to relieve spasms, tics, painful contractions, as well as unpleasant pulling sensations in the muscles. This effect of magnesium is ensured by inhibition of the transmission of impulses from nerves to muscles.
The antiarrhythmic effect of Magnerot is to regulate the contractile function of the heart muscle and ensure its well-coordinated rhythmic work. Due to the antiarrhythmic effect, Magnerot reduces the frequency and severity of angina attacks, reduces vascular resistance, improves blood supply to the heart muscle and prevents spasm of coronary vessels.
In addition, Magnerot is a cardioprotector, as it increases the resistance of heart cells to the adverse effects of various environmental factors. The use of Magnerot in high dosages in the early stages after the development of myocardial infarction can reduce the area of damage to heart tissue, reduce the risk of arrhythmia and increase patient survival.
The antiaggregation effect of Magnerot is to reduce the intensity of thrombus formation, as a result of which the risk of thrombosis and thromboembolism is reduced.
In addition, the drug helps reduce the concentration of total cholesterol and triglycerides, due to which it has an antiatherosclerotic effect.
During periods of stress or high mental, physical and emotional stress, a large amount of magnesium is removed from the body, so during such periods the need for this microelement increases significantly. Taking Magnerot in these situations increases the body's resistance to stress, facilitates tolerance and speeds up recovery after high stress.
The drug also has a positive effect on asthenia, migraines, headaches, dizziness, cramps at night, sleep disturbances, paresthesia (feeling of goosebumps, numbness, etc.), sweating, palpitations and other neurovegetative symptoms caused by any cause. factors.
Magnerot is an effective additional remedy in the treatment of bronchial asthma, since it promotes the removal of histamine and acetylcholine from tissues, which, in fact, are the substances that ensure the development of an asthmatic attack.
Orotic acid, which is formed in the human body as a result of the release of magnesium from its salt, also has a positive effect. Thus, orotic acid accelerates cell growth and improves the process of regeneration and repair of various tissues, including the myocardium.
Release forms, structural analogues and prices
The medication is available in the form of flat tablets, on the surface of which there is a score and a chamfer. The tablets are placed in blisters, 10 pieces each. One cardboard package can contain 2 or 5 blisters, that is, 20 or 50 tablets. The amount of the drug in the package significantly affects its cost. The concentration of the active substance is 500 mg of magnesium orotate dihydrate, which is equal to 32.8 mg of Mg. The color of the dosage form is white, without dark inclusions and impurities.
The drug can be stored for 5 years out of the reach of children. The dispensing rate is over-the-counter. The price of Magnerot is quite high, and not everyone can afford to complete the full course of treatment with this drug. In view of this, the demand for cheap analogues of the drug Magnerot is growing in Russia.
Experts, as a rule, recommend selecting analogues that are similar in composition. These analogues include:
- Magnelis B6.
- Magnesium B6.
- Magne-B6.
- Magwit.
- Magnemax.
These medications are complete structural analogues of the main drug. They are based on an identical mechanism of action, which makes it possible to use all of the listed medications for similar diseases. The main advantage of analogues is their low cost. It is worth knowing that there are also cheaper magnesium-based products that are not complete analogues of Magnerot, but have a similar effect - Asparkam, Cardiomagnyl.
Magnerot release form
You can buy Magnerot in Moscow or other Russian cities without a prescription. The medicine is stored for 5 years from the date of manufacture. It is recommended to keep it out of the reach of pets and children at 25°C. The release form of Magnerot is almost white, flat, round tablets, with a chamfer on both sides, and only one with a line. You can find the drug on sale with two or five blister packs in a cardboard box with instructions. Each blister contains 10 tablets.
Effect of the drug
Providing a certain amount of magnesium in the body is necessary for the normal well-being of the pregnant woman and the harmonious development of the baby inside the womb. A deficiency of this element often causes cramps, indigestion, spasms, and even spontaneous miscarriage. Therefore, Magnerot is an indispensable drug during pregnancy. It helps restore the balance of microelements in the body. The presence of magnesium and orotic acid in its composition ensures the normal course of pregnancy.
The use of the medication helps prevent:
- sudden jumps in blood pressure;
- calf cramps;
- premature contractions;
- fetal anomalies.
For expectant mothers who are susceptible to stressful situations or complain of excessive irritability, doctors also recommend Magnerot during pregnancy.
Reviews of the use of Magnerot, its price
Patients of different groups are often prescribed Magnerot or Magne B6, which have a similar effect, in order to compensate for magnesium deficiency. The effectiveness of the drugs does not appear immediately; there are no dramatic improvements, since it takes some time to achieve a positive result. In their reviews of Magnerot, people usually do not report any side effects. You cannot start using the drug on your own - this is a serious remedy; only after a diagnosis has been made and treatment has been prescribed, the drug Magnerot can be taken. Price and reviews are often of interest to patients. A package of the drug of 20 tablets of 500 mg costs approximately 250-280 rubles.
Magnesium B6 or Asparkam – which is better?
Cheap analogues in Russia are Asparkam and the synonym Panangin. The composition of the preparations includes aspartic salt of potassium and magnesium, which replenishes the deficiency of minerals. When used in a course, substitutes eliminate or prevent arrhythmia, convulsions, and are used for the treatment and prevention of diseases of the heart and blood vessels.
Asparkam is cheaper, however, it is used exclusively in cardiology. Magne B6 is a German product based on magnesium and pyridoxine. Has more indications, clinically studied. The choice of drug is individual.
Positive feedback from patients
The drug "Magnerot" receives mostly flattering reviews from patients. People like the effect of this product. Those patients who constantly suffered from leg cramps note that after the doctor prescribed these pills, their cramps soon disappeared. Also, the Magnerot product has earned special attention from the fair sex, who took this drug before the onset of menstruation. It turns out that these pills help girls during the period of premenstrual syndrome: irritability, nervousness, abdominal pain disappear, and women do not even notice how their mood improves. And all this thanks to Magnerot pills.
However, most of the reviews about this drug are from hypertensive patients and heart patients. People suffering from tachycardia and arrhythmia note the effectiveness of this remedy. It significantly reduces the number of unscheduled heart contractions. At the same time, patients are less likely to experience pain. People also note that thanks to these tablets they no longer experience asthma attacks. Due to such positive changes, patients’ sleep improves. For people suffering from hypertension, the threat of crises has faded into the background. For those who suffered a heart attack, the heart began to tingle less often.
Some patients note that they take this drug in the spring and autumn to relieve seasonal depression. After all, this remedy normalizes the nervous system.
You can find a lot of positive feedback from women about the medicine “Magnerot”. Only positive reviews are given by representatives of the fair sex. Why did women like this drug so much? It turns out that during pregnancy this remedy prevents uterine tone, which is so dangerous due to premature birth. These tablets also make breathing easier and relieve shortness of breath. Women who take these pills no longer suffer from toxicosis.
What is the difference?
When comparing similar drugs, it is also necessary to know their cost, since it may affect the availability of the drug. Moreover, it is necessary to take into account not just the price of 1 package. It is much more important how much treatment will cost for 1 day, week, month. If a drug is available in a large and economical package (in terms of the cost of 1 tablet, for example), this can be its advantage, especially if long-term use is necessary.
Another selection criterion is where the drug is produced. For some, it may be a matter of principle to purchase a medicine from a specific manufacturer. Below is a comparison table that lists the main differences according to several criteria. When analyzing them, you should remember that there is also Magnelis B6 “Forte”, which has a slightly different composition.
Packaging for 50 tablets.
comparison table
Magnerot | Magn. AT 6 |
Active substance | |
Mg orotate dihydrate | Mg lactate/Vitamin B6 |
Contents in 1 tablet | |
500 mg | 470 mg/5 mg |
In terms of Mg2+ | |
32.8 mg | 48 mg |
Recommended daily dose | |
6 tablets per day for 1 week, then 3 tablets per day | 6–8 tablets per day (adults) |
How many tablets are in a package | |
20, 50 | 30, 50, 60, 90 |
Clinico-pharmacological group | |
Mg-containing preparation | A drug that replenishes Mg deficiency |
Pharmaco - therapeutic group | |
Metabolic agent | Mg preparation |
Indications for use (generally) | |
Heart and vascular diseases, spastic conditions, lipid metabolism disorders | Established magnesium deficiency accompanied by symptoms |
Produced | |
Germany | Russia |
Contraindications | |
KSD, salt diathesis, renal dysfunction, cirrhosis with ascites, children under 18 years of age, intolerance | Severe chronic renal failure, phenylketonuria, age less than 6 years, intolerance |
Pregnancy and lactation | |
According to indications | During pregnancy according to indications, during lactation it is not advisable |
From the table it becomes obvious that despite the fact that both drugs contain magnesium ions, the chemical formula of the compound in which this element is located is different (the drugs generally belong to different pharmacotherapeutic groups). In Magnerot it is a salt of magnesium and orotic acid, and in Magnelis B6 it is lactate. Plus, Magnelisa contains vitamin B6.
Cheap structural analogues of the drug
Almost every modern medicine has a number of similar remedies, and Magnerot is no exception. The most popular analogues of the main medicine are drugs of domestic, Ukrainian and Belarusian production due to their low cost.
Magnelis B6
Magnelis B6 is a domestically produced analogue, which is considered the best substitute for Magnerot. Pharmaceutical group – “Mineral impurities (magnesium preparations)”. Magnelis is sold in tablet form. One tablet contains 470 mg of magnesium lactate and 5 mg of pyridoxine. Additional components are povidone, sucrose, lauryl sulfate, silicon, talc, polyvinyl acetate and magnesium stearate. The medication compensates for the lack of Mg in the body and is used for diseases that arise due to its deficiency.
Magnelis B6
Contraindications:
- Allergy to any component of the composition, including lactose intolerance.
- Severe kidney dysfunction.
- Phenylketonuria.
You should also refrain from using the drug when treating children under 6 years of age and women during lactation, since the drug passes into breast milk.
Directions for use: orally (with water). The time of taking the drug depends on the time of eating, since many experts recommend taking Magnelis with meals for better absorption. The average dose of the drug ranges from 6 to 8 tablets per day, depending on the severity of the disease. Frequency of administration – 2-3 times a day. The daily amount of the drug for children is determined taking into account the child’s weight and on average is 3-6 tablets.
Treatment with Magnelis requires constant blood donation for Mg content. As soon as the microelement balance is restored, therapy should be stopped. Magnelis is well tolerated by the body and rarely causes adverse reactions. Possible side effects include: nausea, vomiting, increased gas formation, constipation and abdominal pain. It is also possible to develop allergic reactions in the form of skin rash, itching and urticaria. Magnelis differs from Magnerot in the concentration of the active component in 1 tablet.
See also:
Magnesium B6
Also among Russian-made analogues is the drug Magnesium B6 aptek_ANAdesh-068. The medicine is also a magnesium preparation and is prescribed to people with its deficiency. Mg helps restore performance, relieve spasms, especially of the gastrointestinal tract, and normalize heart rate. The medication also helps eliminate irritability and minor sleep disturbances that were caused by a lack of trace elements in the blood.
Magnesium B6 is sold in the form of coated tablets, shaped like a capsule. The active components in the composition are magnesium lactate (470 mg) and pyridoxine hydrochloride (5 mg) + vitamin B6. The presence of vitamin B6 in the structure helps to shorten the absorption period of Mg and accelerate its entry into the body's cells. The composition also contains milk sugar (therefore, people with lactose intolerance are prohibited from taking the medication). Magnesium B6 is contraindicated for the same diseases and conditions as Magnelis. You should refrain from taking the medication while breastfeeding.
For an adult, the initial daily dose of the drug is 6-8 tablets, which is divided into 2-3 doses. Children over 6 years old and weighing more than 20 kg should start therapy with 4 tablets per day. As a rule, the drug is taken for 4 weeks, or until normal Mg levels in the blood are restored. Taking Magnesium B6 can cause constipation, abdominal pain, bloating, nausea with vomiting and allergies. An overdose of Magnesium is possible only if at the beginning of therapy there was a sufficient amount of the microelement in the blood. Difference from Magnerot: contains a different concentration of Mg.
Magnesium overdose
Magwit
Magvit is a Belarusian substitute for Magnerot, the active ingredient of which is magnesium citrate along with pyridoxine. The manufacturer used lactose, potato starch and magnesium stearate as auxiliary components. Medicinal group – mineral supplements.
The medication is available in the form of yellow capsules, the shell of which contains glycerol, pharmaceutical gelatin, sodium lauryl sulfate, nipazole, nipagin, purified water and yellow dyes. One cardboard package contains 30 capsules placed in blisters.
Magvit helps restore Mg balance in the body. The medicine is used for diseases and symptoms that were caused by Mg deficiency. These symptoms include:
- Minor sleep disturbances.
- Fast fatiguability.
- Increased anxiety and irritability.
- Rapid heartbeat in the absence of cardiovascular pathologies.
- Intestinal spasms.
- Muscle cramps.
Magvit is contraindicated for people with normal levels of Mg in the body, as well as patients with lactose intolerance, kidney dysfunction and children under 6 years of age. Well tolerated by the body. Possible side effects include bloating, abdominal pain and constipation.
Constipation
Magvit is prescribed 1-2 capsules several times a day. It is better to take the drug during meals with a glass of water. The maximum dose is 6 capsules/day. The course of treatment depends on the speed of restoration of magnesium levels in the body. The drug interferes with the body's absorption of iron. Since the launch of the drug until now, no cases of overdose with Magvit have been reported. Magvit differs from the main drug in dosage form and Mg concentration.
Magnemax
Magnemax is a Ukrainian-made magnesium preparation, which is sold in the form of two-layer tablets consisting of the preparation itself and a film shell. External characteristics of the form of sale: white tablets, shaped like an oval. On one side there is a notch on the surface of the tablet.
Magnemax belongs to the B complex of vitamins and minerals. The action of the drug is based on Mg (100 mg/1 tab) and pyridoxine (10 mg/1 tab). The form-modeling components are titanium dioxide, talc, triacetin, magnesium stearate, polyethylene glycol and lactose.
Mg is a vital element that is involved in almost all enzymatic processes, being part of many body tissues, including skeletal. Therefore, with Mg deficiency comes hyperexcitability, irritability, weakness, tingling in the muscles and increased heart rate. Magnemax eliminates these symptoms by increasing the amount of Mg in the blood.
Causes of magnesium deficiency
The drug is contraindicated in patients with severe kidney damage, excess vitamin B6, myasthenia gravis, low blood pressure, lactose intolerance, diarrhea and phenylketonuria. Magnemax is also contraindicated in breastfeeding women and children under 6 years of age.
The tablets are taken orally. The medicine must be swallowed whole, without chewing and with a significant amount of liquid. The average daily dose for an adult patient is 3-4 tablets. Frequency of administration – 2-3 times/day. The dose of the drug for a child is selected taking into account his weight. Thus, children weighing more than 20 kg are allowed to take 2-4 tablets per day, divided into a couple of doses.
Complications while taking Magnemax manifest themselves in the form of nausea, vomiting, constipation and allergic skin reactions. The development of an overdose is possible only in the presence of concomitant kidney disease. Magnemax differs from the main drug in the concentration of the active substance, auxiliary components and the presence of a film shell.
See also:
Russian analogues of Magnerot
How much Magnerot costs in tablets can be easily found out in any pharmacy, since the drug is in demand. However, not many Russian residents can afford to buy medicine, much less complete the entire course of treatment. The price of the Russian analogue of Magnerot is significantly reduced due to the lack of costs for transportation, advertising, and research of the Russian market. The domestic pharmaceutical market offers magnesium-containing products with the most similar therapeutic effect, but with a different active component (various magnesium compounds). Russian analogues of Magnerot:
- Vitrum Mag;
- Magnelis B6;
- Alditive magnesium;
- Magne Positive;
- Magnesium plus B6;
- Magne Express.
Precautionary measures
Magnerot, like other drugs containing magnesium, is prohibited for use in the following conditions:
- the presence of kidney stones;
- renal failure:
- severe liver disease (cirrhosis);
- individual intolerance to the drug.
Advice! It should be borne in mind that the tablets contain lactose, therefore Magnerot is prohibited for use in conditions associated with intolerance to this substance.
Side effects
Magnerot is almost always well tolerated, but the development of allergic reactions cannot be ruled out. In rare cases, the following may occur:
- stool disorder;
- the appearance of a rash on the skin;
- abdominal discomfort.
Overdose
If a woman has healthy kidneys, then even if the dosage is chosen incorrectly, no unpleasant consequences will develop. Excess magnesium will simply be removed from the body. If renal function is impaired in case of overdose, toxic reactions are observed. Symptoms of magnesium poisoning:
- a sharp decrease in pressure;
- vomit;
- depressed mental state;
- slower reactions;
- in severe cases - coma and cardiac arrest.
When signs of magnesium poisoning appear, a process of rehydration and diuresis is carried out. In case of renal failure, hemodialysis is additionally performed.
Side effects and special instructions
Side effects
When treated with Magnerot, complications in the functioning of the following life support systems of the body are possible:
- Digestive – diarrhea and unstable stool. No special treatment for symptoms is prescribed - it is enough to reduce the dose of the drug taken.
- Others are the manifestation of an allergic reaction when interacting with one of the substances in the composition.
special instructions
- Treatment with Magnerot during pregnancy and breastfeeding is not prohibited. Rather, it will even be useful to expectant and young mothers due to the acute lack of magnesium in the body at this stage of life.
- However, the use should still be treated with extreme caution and the drug should be prescribed only when the risk of treatment for the child is less than the benefit for the mother.
- Taking the drug in children under 18 years of age is strictly contraindicated.
- The drug can be used by professions that require high concentration of attention such as driving a car and others.
Drug interactions
- It is undesirable to use drugs similar to Magnerot due to possible hypervitaminosis.
- With the simultaneous use of drugs with iron, sodium and tetracyclines in the composition, it is possible to reduce their dose perceived by the body. Therefore, arrange an interval between taking medications of 2-3 hours.
- The effect is reduced when consumed simultaneously with diuretics, oral contraceptives, insulin and muscle relaxants.
In Russia, one medicine with an active substance is officially registered - magnesium orotate. This is Magnerot. The medicine is also sold in most European countries.
Peculiarities
Magnerot can be taken for a long time. It must be remembered that the following points can lead to magnesium deficiency in the body:
- disturbances in the functioning of the stomach and intestines;
- eating foods with a small content of the required element;
- pathological addiction to drinking alcohol, as well as the presence of mental disorders (due to decreased reabsorption of magnesium in the renal canals and increased excretion of magnesium from the body);
- taking certain medications (for example: oral contraceptives, diuretics, muscle relaxants, glucocorticoids, insulin);
- the patient’s well-being, which requires increased magnesium intake (stress, pregnancy);
- hypodynamia (impaired body functions of the musculoskeletal system, blood circulation, breathing, digestion).
Substitutes for Magnerot with a similar effect
In addition to structural analogues, there are also drugs with an effect that is similar to that of Magnerot, despite a different composition. Such similar drugs include Asparkam and Cardiomagnyl.
Asparkam
Asparkam is a medicine that helps restore the balance of potassium and magnesium ions in the body. The drug belongs to the pharmaceutical group of mineral supplements in combination. Consists of 2 active ingredients and several auxiliary components. The active ingredients are magnesium and potassium aspartate, 175 mg of each in 1 tablet. Auxiliary components are talc, starch and calcium.
Asparkam is sold in the form of white tablets, the surface of which has a notch and a chamfer. There is also a drug in the form of an injection solution, 1 ml of which contains 40 mg of active ingredients. It is used for potassium and magnesium deficiency, as well as as an adjuvant therapy for chronic cardiovascular diseases, including heart failure and arrhythmia. Asparkam also helps people recover after myocardial infarction.
Contraindications to taking Asparkam are the following diseases:
- Addison's disease.
- Intolerance to the composition of the medication.
- AV block.
- Kidney failure.
- Shock.
- Problems with urination.
- Excess potassium and magnesium.
- Ulcer of the stomach and duodenum.
The drug can be used orally and intravenously, depending on the dosage form. Before administering Asparkam intravenously, it is diluted in 50-100 ml of 5% glucose solution. The permissible single dose is 1 ampoule.
The tablets are taken orally after meals, since gastric juice reduces the effectiveness of Asparkam. The average daily dose of the medication is 3-6 tablets, 3 times a day.
Possible adverse reactions:
- nausea;
- diarrhea;
- internal bleeding;
- stomach ulcer;
- epigastric pain;
- dry mouth;
- hypotension;
- AV block;
- cardiac conduction disturbance;
- seizures;
- skin rash and itching;
- breathing problems.
Asparkam, unlike Magnerot, has a more extensive list of indications and contraindications, and is also available not only in the form of tablets, but also in the form of an injection solution. Prohibited for use in children.
Asparkam
Cardiomagnyl
Heart-shaped tablets based on acetylsalicylic acid (ASA), magnesium hydroxide and magnesium stearate. The drug belongs to antithrombotic agents. ASA has anti-inflammatory, antiplatelet, antipyretic and analgesic effects. The drug is used to treat coronary artery disease and as a means of preventing the formation of blood clots in people who are at risk.
Cardiomagnyl is prohibited for use by people with intolerance to ASA and other substances in the composition, as well as asthma, bleeding tendencies, ulcers and serious damage to the kidneys, liver and heart in the form of acute failure. The medication is contraindicated for women during pregnancy and lactation.
Method of administration: inside. If necessary, the tablet can be crushed or dissolved in a small amount of water. The therapeutic dose of Cardiomagnyl is 150 mg per day, and the prophylactic dose is 75 mg.
Taking medication can cause the following complications:
- Internal bleeding.
- Stomach pain.
- Dyspeptic disorders.
- Ulcer.
Peptic ulcer
- Bleeding from the nose and gums.
- Anemia.
- Allergic skin reactions.
Cardiomagnyl differs significantly from Magnerot, from its composition to its mechanism of action. Perhaps the only similarity between the medications is the presence of magnesium in the structure.
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