Can it be used?
It is worth understanding that endometriosis itself is a hormonally dependent disease. With it, pathological, overly active cell division occurs in some areas of the endometrium. This process is not associated with any external factors, it is not inflammatory or infectious. Antibiotics are drugs to combat pathogenic microorganisms, that is, bacteria, microbes, spores of some fungi (not all antibiotics are effective against the latter type of pathogen).
That is, since there are no pathological microorganisms on the mucous membranes in this disease, the use of antibiotics may seem pointless. It will not cure the very cause of the disease, since it does not affect it in any way. However, sometimes antibiotics are still prescribed for endometriosis. Why is this being done?
The fact is that the presence of such a disease indicates reduced local and general immunity of the body. Endometriosis develops with reduced immunity and reduces it even more significantly. Therefore, tissues are especially vulnerable to pathogenic microorganisms and fungi. The immune system cannot fight them, so inflammatory processes and infections develop very quickly. Antibiotics are prescribed specifically to defeat such concomitant diseases.
In itself, endometriosis is not a contraindication for taking antibiotics.
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Antibiotics for endometriosis of the uterus - which ones to use
Content
Is it worth taking antibiotics for endometriosis, since this disease cannot be associated with the development of a bacterial or fungal infection in the body?
Although the development of this uterine disease in the female body does not cause the development of a specific infection, it is still necessary to take antibiotics. The gynecologist who is observing the woman selects the drug.
How do such drugs work, are they always needed, and why are they prescribed to a patient for the treatment of endometriosis?
Is it possible to take antibiotics for this disease?
First, we need to remind you that endometriosis is a hormonally dependent disease in which increased cell division occurs in the upper layer of the uterus, which is called the endometrium. This process cannot be associated with the development of infection in the body, since its course is neither infectious nor inflammatory.
Antibiotics are drugs that quickly destroy pathogenic microflora, namely fungus, microbes and bacteria.
That is, in other words, why should a woman suffering from uterine endometriosis take this group of medications if she does not have microorganisms dangerous to health in her body? Doctors quite often prescribe antibiotics to patients with this pathology as a result of a severe decrease in immunity, which is further undermined due to the development of the disease. That is why the body of any woman is quite susceptible to the development of certain inflammatory diseases that will cause serious harm to the patient’s health. Therefore, during the course of endometriosis, the patient is prescribed one or more antibiotics, since it is quite easy for microorganisms to enter the genitals and cause this or that disease in the shortest possible time.
Endometriosis especially often leads to the development of the following diseases:
- cystitis;
- urethritis;
- urolithiasis disease;
- pyelonephritis.
When taking antibiotics, they quickly defeat many pathological processes occurring in the body, which are caused by pathogenic microflora.
As a result, the woman’s symptoms of inflammation and infection disappear very quickly. In addition, when these medications are taken correctly, the patient’s signs of endometriosis are reduced and its course is also alleviated.
This is due to the fact that this process quite significantly reduces the so-called tissue immunity, due to which the rapid growth of endometriosis cells is suppressed. That is why, with reduced immunity, such a pathology will develop quite quickly, which means it will cause a lot of harm to a woman’s health.
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During the course of uterine endometriosis, antibiotics should be prescribed in the following cases:
- endometriosis was accompanied by a fungal infection;
- the presence of complications of certain infectious diseases that develop on the genitals;
- the presence of previous inflammatory pathologies in the woman’s organs of the reproductive and urinary systems.
In other cases, this group of drugs is not prescribed to the patient, since it can cause a large number of health complications, as well as side effects. One of these actions is the suppression of the functioning of the immune system, which further aggravates the course of uterine endometriosis.
It is known that any group of antibiotics has many contraindications, but they do not cause significant harm to a woman’s health.
But it is still prohibited to take drugs in some cases, namely:
- kidney failure or other dysfunction of this organ;
- liver failure or other pathologies of this organ;
- pregnancy and breastfeeding.
Contraindications consisting in disruption of the liver and kidneys have a good reason, because it is these organs that remove toxins and other chemical components found in these drugs. According to doctors, the most toxic are antifungal antibiotics, which contain the largest amount of harmful substances.
During pregnancy and breastfeeding, some types of medications are still prescribed, but this is done according to strict doctor’s instructions and only after calculating the correct dosage.
What antibiotics are prescribed for uterine endometriosis
All antibiotics prescribed during the course of uterine endometriosis are divided into three types.
These include:
- Broad spectrum antibiotics. Most often, a woman with endometriosis is prescribed one of the following drugs: Amoxiclav, Unidox and Macropen. All these medications are presented in the form of tablets, which must be taken in full course, and, of course, without breaking it. On average, the medications should be taken for 10-14 days, depending on the severity of endometriosis. The dosage of such medications is prescribed only by the attending physician.
- Cephalosporins. Lesser-known drugs that are used today only in extreme cases. However, only they can help some patients. This group includes the following types of drugs - Cedex, Ceftazidime, Ceftriaxone, and so on. Like the previous group of antibiotics, cephalosporins are taken orally for a full course, the duration of which is 10 days.
- Antifungal compounds. This type of medication is prescribed by a doctor only in the most advanced cases, when a woman can be attacked by fungal infections at any time. These drugs include Nystatin, Fluconazole and Flucostat. Each medicine is prescribed only by a doctor in a strict dosage. Some medicinal compositions are in the form of suppositories, which can be used if the development of a particular disease is suspected.
Any type of antibiotics should be prescribed to a patient only by a doctor who will conduct a full diagnosis of the body, evaluate the test results and understand what kind of treatment the woman needs. Otherwise, unjustified use of medication causes serious complications that undermine women's health and also aggravate the course of uterine endometriosis.
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Efficiency
Why take medications of this group and what effect do they have? With long-term regular use, they help defeat the pathological process caused by pathogenic microorganisms. As a result, severe symptoms of infection and inflammation disappear. The symptoms of endometriosis may also become less pronounced, since the presence of an inflammatory or infectious process worsens the course of this disease.
This is due to the fact that such a process further reduces local tissue immunity. Namely, it suppresses partially active cell division. Therefore, when it is reduced, endometriosis develops much faster. For this reason, inflammations and infections must be treated promptly.
Indications
In what cases is it recommended to prescribe antibiotics? Typically, this is done in the following situations:
- The presence of complications of an infectious-inflammatory nature, often endometritis, endocervicitis;
- The presence of associated infectious and inflammatory diseases of the reproductive and genitourinary systems;
- Attachment of a fungal infection.
In other cases, medications of this class are never prescribed because they have many side effects. In particular, they further reduce immunity, which theoretically could accelerate the development of endometriosis. However, most often this does not happen, since therapy with antibacterial agents is carried out under the “cover” of hormonal treatment of one type or another.
Contraindications
As mentioned above, antibiotics have many contraindications. But in general, they are not too severe, and the potential benefits of taking them outweigh the potential harm. But there are several strict restrictions on taking drugs from this group:
- Renal failure or other suppression of renal function;
- Liver failure or other depression of liver function;
- You should not take such medications during breastfeeding or pregnancy, although pregnancy is not a very common occurrence with endometriosis.
Contraindications regarding the functioning of the kidneys and liver are due to the fact that these are the ones that remove all toxins and chemicals contained in the drugs. If the functioning is insufficient, then the health condition may worsen, and the antibiotics themselves will significantly negatively affect the kidneys and liver. Antibiotics that help against fungi have a particularly negative effect, since they are the most toxic.
As for pregnancy and lactation, this contraindication is not absolute, but relative. Some types of antibiotics in some cases can be used as directed by a doctor and in strictly calculated dosages.
Remember that it is not recommended to drink alcohol while taking antibiotics, as it will reduce the effectiveness of treatment.
What treatment methods are there?
In total, there are three main ways to treat this disease:
- Surgery without organ removal;
- Radical surgery;
- Conservative therapy.
The choice of the recommended technique directly depends on the patient’s age, location of the lesion, stage of the disease, as well as the need to restore the reproductive system.
If the patient is a young woman, then in most cases the most gentle treatment regimen is used, namely surgery and hormone therapy. This technique does not inhibit the development of the egg, so the risk of complications is not so great.
However, most patients are more mature (35-40 years old). Treatment of endometriosis in this case is carried out depending on the location of the lesion. The therapy is carried out comprehensively:
- Surgery to remove nodules and cysts, dissect adhesions and burn out lesions;
- Intensive therapy with hormonal drugs;
- A course of immunostimulants.
In most cases, it is not possible to completely cure endometriosis without surgery, and therefore experts recommend a comprehensive type of treatment. However, there are cases when surgery is not recommended and conservative treatment is carried out:
- Infertility;
- Reproductive age of the patient;
- The disease is asymptomatic.
Surgery is performed under the following circumstances:
- The woman has a somatic pathology;
- The presence of other diseases of the genital organs;
- Endometriosis of the scar or navel;
- Medicines do not give the desired effect.
At the same time, cases when urgent radical surgical treatment is required cannot be excluded:
- Severe form of adenomyosis;
- Ovarian endometriosis;
- Previous methods do not lead to recovery.
Only a doctor can announce the necessary treatment regimen; you should not rush and take hormonal medications. In this case, without the advice of a specialist, you can only use homeopathic medicines. Homeopathy is a harmless medicine that can normalize human hormonal function. Despite this, you should approach the choice of such a drug seriously, since they are not universal and will not suit everyone.
Kinds
Most often, broad-spectrum drugs are prescribed. Cephalosporins are also sometimes preferred. The drugs are administered by injection or orally, in the form of tablets. Antibiotic therapy is also supplemented with anti-inflammatory drugs (most often non-steroidal). These are aspirin, ibuprofen, diclofenac. They help remove inflammation, while antibiotics fight microorganisms.
Sometimes with endometriosis of the uterus there is severe pain. In this case, antispasmodics are prescribed. This is no-shpa, spasmalgon, etc.
Wide spectrum
Most often, one of three drugs is used.
Broad spectrum antibiotics
Name | Mode of application | Dosages | Price, rubles |
Macropen | Orally | One 400 mg tablet three times a day, after meals. Course duration 7-14 days | 260 |
Unidox | Orally | 200 mg per day on the first day, 100 mg per day on all subsequent days of treatment. Course duration is about 10 days | 330 |
Amoxiclav | Orally | One 1000 mg tablet once daily for 7-14 days | 650 |
It is important to remember that your doctor should recommend dosages.
Cephalosporins
Less widely used means, but for some types of pathologies may be more effective.
Cephalosporins
Name | Mode of application | Dosages | Price, rubles |
Ceftazidime | Orally | 500-1000 mg every 8 to 12 hours for a week or more | 72 |
Ceftriaxone | Oral, injection | 1-2 g of the drug once a day for 5-10 days | 25 |
Tsedex | Orally | 400 mg once daily for 5-10 days | 50 |
A suitable drug is selected by a specialist.
Antifungal
Prescribed for fairly advanced cases of the disease.
Antifungal agents
Name | Mode of application | Dosages | Price, rubles |
Fluconazole | Orally | 150 mg per day, once or as prescribed by your doctor | 15 |
Nystatin | Orally, intravaginally in the form of suppositories | 1-2 suppositories per day for at least a week. When taken in tablets, the dosage and duration of treatment is determined by the doctor. | 86 |
Flucostat | Orally | 150 mg per day, once or as prescribed by your doctor | 350 |
The dosage regimen for these drugs is quite complex and depends on many factors. Antifungal drugs are sold under a variety of brand names. Moreover, their composition is often similar. The cheapest and most effective is Fluconazole. It is sold in packages of one capsule, costing from 11 rubles.
Adverse reactions
It is difficult to find an active drug that is completely free of side effects. In the case of Ceftriaxone, the list will be insignificant:
- The occurrence of nausea and vomiting;
- Diarrhea and flatulence;
- Pain or discomfort in the hypochondrium on the right side, which is associated with impaired liver function;
- Development of dysbiosis in the intestines;
- The occurrence of candidiasis in the vagina.
Ceftriaxone is one of the most effective antibiotics that are part of antibacterial therapy for inflammation of the appendages or endometritis. Due to its high efficiency, minimal number of contraindications and minor side effects, recovery occurs in a short time.
Source 1ivf.info
Good afternoon, dear women. Our material today is about antibiotics for endometriosis. We will devote this article to the topic of treating endometriosis with antibiotics. Why did we decide to raise this issue?
- Firstly, endometriosis is a common female disease, so every representative of the fairer sex should have at least a general understanding of this disease.
- Secondly, the disease is not infectious, which means that strong drugs are used to eliminate it in individual cases.
And most importantly, if antibiotics are used incorrectly for endometriosis, you can only worsen your condition and face the most tragic consequences (for example, infertility).
General characteristics of the disease
Endometriosis is a gynecological disease characterized by the proliferation of cells in the inner layer of the walls of the uterus (endometrium) outside this layer. The disease can be genital (cells appear only in the genital area) or extragenital (formations are present in the navel area, in the intestines).
The reasons for the development of endometriosis are the same as for fibroids. Both diseases appear due to hormonal imbalances that stimulate increased cell division. Typically, the best treatment option for endometriosis is hormone therapy.
In some cases, surgery is performed. The question arises: when do potent drugs take part in eliminating the disease?
When are antibiotics used for endometriosis, and what specific medications do doctors prescribe?
Antibiotics are used in cases where endometriosis is accompanied by infectious and inflammatory complications (endometritis, endocervicitis). Doctors often prescribe broad-spectrum medications.
These include protected penicillins, macrolides, thienam, doxycycline (belonging to the group of tetracyclines).
Gynecologists often prescribe antibiotics from the cephalosporin group: ceftazidime, ceftriaxone, cedex. These medications are introduced into the body by injection or drip intravenous infusion.
If complications have received little attention and they have developed into an advanced form, antifungal antibiotics may be prescribed. This group of drugs includes Mikosist, Flucostat, Nystatin.
It should be borne in mind that the fight against infectious and inflammatory complications cannot be achieved only with the help of antibiotics.
In most cases, tablets that have an anti-inflammatory effect (aspirin, ibuprofen, diclofenac) are also prescribed. For severe pain, antispasmodics (no-spa, spasmalgon) are prescribed.
List of contraindications
Unfortunately, not everyone is allowed to take antibiotics. In particular, treatment with their help is contraindicated for women suffering from renal or liver failure. It is these organs that are responsible for processing everything that enters the body. If your liver or kidneys are unhealthy, antibiotics will only make their condition worse.
It is better to refrain from such medications during lactation (sometimes their use is allowed, but only after the appropriate doctor’s order). In addition, during the period of using antibiotics, it is strongly recommended to give up alcohol.
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We also recommend that you familiarize yourself with the course by Irina Zhgareva, dedicated to such a disease as cervical erosion. With its help you will learn what to do if this disease is detected.
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Source sosed-domosed.ru
Is it necessary to take antibiotics for endometriosis, since this process is not associated with the activity of pathogenic microorganisms? However, doctors quite often prescribe such antibacterial drugs for this diagnosis. How do such medications work, why are they prescribed, and what contraindications do they have? This is discussed in this material.