Side effects of taurine and contraindications
Experts are wary of the effects of taurine, since it is a very active substance.
Doctors believe that it has the ability to have an excessive effect on the heart, lowers blood pressure, provokes increased production of bile and aggravates chronic diseases. Important! Before you start taking medications with taurine, you should definitely visit a doctor and make sure there are no contraindications. In this case, there will be benefit from taking it, and not harm.
- Taking amino acids is not recommended if you have gallstones or liver disease.
- For gastritis with high acidity and stomach ulcers, the substance can also be harmful.
- If you have low blood pressure, taking taurine is prohibited; heart failure and other pathological changes in the cardiovascular system can progress when exposed to this substance.
- Continuous intake of taurine into the body will lead to harm in the form of wear and tear. The beneficial properties of the substance can be obtained only with minimal intake.
- Pregnant and lactating women, as well as children, can take taurine only as directed and under the supervision of a doctor.
Important! You cannot combine taurine and caffeine or alcohol. This will cause great harm to the body.
A thorny story
The discovery of taurine belongs to two German biochemists who, while studying the composition of ox bile in 1827, isolated and described a new substance.
It did not claim to be a sensation and did not attract much attention in scientific circles. The events of the 60s of the 20th century that took place in America forced scientists to return to the works.
To the chagrin of many cat owners, their pets began to lose their eyesight en masse and die from heart disease. The cause of the disease turned out to be not viruses and microbes, but a new animal food with a complete absence of taurine in its composition.
The time of detailed research and new discoveries has begun, sometimes with unexpected results.
Eye drops
Taufon is an eye drop that contains 4% taurine. Their indications for use are cataracts, glaucoma, degeneration of the cornea, macula and posterior pole, injuries of the eye and orbit. Doctors usually prescribe Taufon eye drops in courses, with breaks of several months. However, it is advisable to drip them continuously in order to maintain a consistently high concentration of taurine in the eye tissues.
Eye drops Taufon. Active ingredient: taurine 4%.
People try to arbitrarily use this remedy for discomfort and dry eyes and naturally get negative results. Because it is intended for long-term treatment, and not for quick relief of unpleasant symptoms. The instructions do not indicate any contraindications or side effects. But many patients complain that they experience discomfort when they drop Taufon into their eyes. In this case, you can try replacing these drops with taurine tablets. Don't expect quick results. Evaluate the effect after at least a month.
Taurine eye drops - benefits and harms
We have already figured out what effects the main active ingredient in the medicine can have on the body. The time has come to concentrate on Taurine drops, the benefits and harms of which for humans will be described below. The high popularity of the medicine speaks for itself, but before using it, it doesn’t hurt to once again weigh all the existing pros and cons.
Taurine eye drops - benefits
The drug is prescribed to combat various ophthalmological problems.
Taurine for eyes - benefits:
- In case of corneal tissue dystrophy, drops restore the balance of fluids, put tissue trophism in order and help strengthen cell membranes.
- Dystrophy of the retinal membrane. At the same time, taurine restores neural connections and normalizes metabolic processes.
- For cataracts, the product nourishes the cells and helps remove toxins more quickly, so the eye membranes are restored faster.
- Drops fight glaucoma by restoring nerve-impulse connections and blood vessels. In addition, Taurine reduces pressure inside the eyes.
Taurine eye drops - harm
As a rule, Taurine eye drops are absorbed very well by the body and do not cause any aggressive combinations with other medications, but they cannot be called completely safe. The medication sometimes causes side effects in the form of allergies, itching, burning, and stinging in the eyes. In order to avoid encountering them, it is better not to use Taurine for those for whom it is not suitable due to contraindications, and at the first suspicious symptoms after starting treatment, you should consult a doctor, and the drug will either be replaced or excluded from therapy completely.
Description and composition of Taurine eye drops
Taurine drops are a useful drug that can accelerate regenerative processes on the outer surface of the cornea of the eye in case of injury and damage. It is popular due to its reasonable price and wide availability: it can be found in every pharmacy.
In a general biological sense, taurine is a beneficial sulfonic acid. It can be formed in the body from the amino acid cysteine. Taurine performs an anticonvulsant function, has the ability to have a positive effect on metabolic processes, plays an important role in energy balance, and is also involved in neurotransmitter changes in the brain.
Important! With age, the body's ability to independently produce taurine decreases, so it is necessary to take this useful drug additionally.
In pharmacology, taurine began to be used relatively recently. It is available in the form of transparent, colorless drops. This is a 4% solution of amino acids with distilled water. Sometimes an antiseptic or preservative (methylparaben - nipagin) may be added. 1 ml of drops contains up to 40 mg of taurine. They are usually packaged in small bottles of 1.5 - 15 ml with a built-in dispenser or pipette.
Taurine drops - composition
Taurine eye drops, the harms and benefits of which will be described below, are available in polyethylene bottles with built-in droppers or are supplied complete with a pipette. The medicine should be stored at a temperature no more than 15 degrees. It is undesirable for the product to be exposed to direct sunlight. If all conditions are met, the product will be stored for up to 3 years when closed and up to 1 month when opened.
The short shelf life is explained by the fact that the main active ingredients of the medicine cannot retain their properties for too long when in contact with air. Taurine eye drops consist of the following components:
- taurine is the main active ingredient, which contains about 40 mg in 1 ml;
- water for injections;
- methyl parahydroxybenzoate.
Taurine - what is this substance?
To understand the harms and benefits of a medicine such as Taurine eye drops, you need to understand what it consists of. The main substance in the drug is an amino acid, which is responsible for many important processes that occur in the body. Taurine is involved in:
- restoration of damaged tissues;
- bile production;
- protection of the organs of vision;
- fat metabolism;
- breakdown of various beneficial substances;
- correction (in particular inhibition) of nerve impulses;
- preventing seizures;
- restoration of the normal metabolic process.
Taurine, what kind of substance is this for the body? This is an indispensable biologically active agent. In the body it is produced during the conversion of cysteine. In pharmaceuticals it looks like a white crystalline powder. It dissolves most quickly in water, but when added to ethyl alcohol, taurine almost does not change its consistency.
What does taurine help with?
There is no doubt that the substance has an irreplaceable effect for the body. Taurine is used in various fields. This component:
- slows down the aging process;
- prevents oncology;
- is an excellent antioxidant;
- has a beneficial effect on the heart;
- quickly and effectively restores blood pressure;
- helps keep blood sugar at normal levels;
- fights stress;
- can be used as an excellent diuretic;
- removes toxins and waste from the body;
- stabilizes the functioning of the nervous system;
- relieves swelling;
- stimulates active and productive brain activity.
Taurine eye drops are good for problems with the cornea and retina - mechanical damage, injuries. The main component of the medicine, among other things, can also be used for weight loss. It is true that the remedy is effective only when a person simultaneously follows a regimen, adheres to proper nutrition and takes care of himself in every possible way.
What is taurine and what is it for?
Not everyone understands exactly what taurine is. In fact, it is a beneficial amino acid that the human body requires for normal functioning. It is thanks to it that benefits are obtained in the form of cell restoration and division. Taurine is responsible for the process of lipid metabolism and the transmission of nerve impulses. The body can synthesize taurine based on amino acids that contain sulfur - cysteine and methionine.
The main difference between taurine is its ability to reside in tissues in a free form. Most of it is found in:
- heart muscle;
- spinal cord and brain;
- kidneys;
- retina;
- muscles
Of course, this useful substance is extremely necessary for the human body. Taurine is able to completely dissolve in liquid and has the property of neutralizing harm, restoring the normal functioning of all organs.
Tuarine deficiency
It is clear that tuaric acid is a beneficial substance for humans. But perhaps its effect is exaggerated, and its absence is not so terrible? After all, taurine does not appear immediately in mother’s milk and in the baby’s body itself, and in industrial baby food it may be completely absent. So is there any harm or benefit from taurine deficiency?
Based on the results of numerous scientific studies, it has been found that a lack of taurine can have very serious consequences for a growing body. This did not become clear immediately, because... In the first months and even years of life, the child seems to develop normally. But the consequences can be dire.
Experts have determined that the risk group sensitive to tauric acid deficiency primarily includes:
- premature;
- newborns with functional and/or morphological immaturity;
- received hypoxia and central nervous system damage during childbirth.
And even artificial feeding without taurine or with cow's milk, where the acid is contained in minimal quantities, leads to a decrease in intellectual potential, hearing loss, poor vision and diseases of the biliary system.
An overdose of taurine in the body leads to lethargy, a feeling of satiety, and drowsiness. Regular artificial administration of sulfonic acid in large quantities extinguishes the body’s natural function of its synthesis, which leads to metabolic disorders, excess weight, decreased immunity, etc. An irregular excess of tauric acid can be excreted from the body through the kidneys and intestines.
Pharmacological properties
Pharmacodynamics
The drug has a metabolic effect and is an anti-cataract agent.
Taurine (sulfoxyglycine) is a sulfur-containing amino acid that is formed in the human body during the metabolism of cysteine. It improves energy processes, stimulates repair in dystrophic diseases and processes that are accompanied by metabolic disorders in the tissues of the eye. Since taurine contains sulfur, it normalizes the functions of cell membranes, as well as metabolic and energy processes; due to the accumulation of calcium and potassium ions, it helps to maintain the electrolyte composition of the cytoplasm; improves the conduction of nerve impulses.
Pharmacokinetics
Taurine is highly sensitive to eye tissues. The maximum accumulation of the drug in the retina of the eye is observed 20–30 minutes after intraocular administration. With the parenteral route of administration, approximately the same concentration of taurine in the retina is established after 4–6 days of daily administration of the drug.
When instilled, the penetration of taurine into the eye tissue slows down, that is, to achieve a therapeutic effect, a course of the drug is required according to a certain scheme.
The main route of drug elimination is through the kidneys (most of the drug is excreted in unchanged chemical form and only a small amount is metabolized to form conjugated bile acid).
Beneficial features
Taurine is necessary for the normal functioning of the liver, heart, retina, blood cells and central nervous system. It is involved in vital processes occurring in the body - maintaining normal metabolism, regulating blood pressure, and digesting fats.
central nervous system
In the central nervous system, taurine plays a role as a neurotransmitter amino acid.4 It is believed to promote the formation of new cells in the hippocampus, the limbic part of the brain associated with memory and emotions.5
Sport
It is believed that it lowers triglyceride levels, thereby reducing the likelihood of obesity.6
Experiments in mice have shown that taurine is essential for maintaining skeletal muscle function.7
The effect of taurine on improving athletic performance has been experimentally proven. Scientists at the University of Stirling in Scotland, who study the effects of exercise on health, conducted a study among a group of middle-distance runners who took 1,000 mg of taurine two hours before a race.
90% of subjects showed improvement in results by a few seconds. And we know that in athletics, a difference of a few seconds can make a big difference. There were no negative effects on breathing or heart rate. Research has concluded that there is a 99.3% chance of athletes taking taurine to improve their performance8.
If your goal is muscle development and increased strength, then taking taurine before training will have a positive effect on recovery processes, and intense physical activity will be easier to tolerate due to its antioxidant effects.
Benefits for the eyes
It is difficult to overestimate the role of this amino acid in maintaining eye health: it improves metabolic processes in eye tissues and helps restore the functions of cell membranes. Taurine in the form of eye drops is prescribed for corneal dystrophy and injuries, dystrophic lesions of the retina, and cataracts.
Taurine for cats
Many people are interested in why manufacturers add taurine to cat food, what benefit or harm it might have. For humans, taurine is a conditionally essential amino acid. This means that the body knows how to produce it. Healthy people are unlikely to need to take taurine in tablets or capsules. However, the situation is different for representatives of the cat family. They cannot synthesize taurine, although they need this amino acid for normal metabolism.
For cats, taurine is an essential amino acid. They can only get it through food. Taurine deficiency in cats weakens vision, eventually leading to blindness, and can also cause hair loss and dental caries. For this reason, cat food manufacturers add taurine to their products. The recommended taurine content is 0.1% in dry food and 0.2% in wet food.
What is taurine for?
Taurine contains a number of minerals, including potassium, calcium and sodium.
The biologically active component has the following positive effects on the body:
- lowers blood glucose and cholesterol levels;
- acts as a powerful antioxidant;
- activates blood circulation;
- normalizes the structure of the retina, accelerates its recovery after injury;
- puts the myocardium in order;
- improves overall well-being and gives strength.
Amino acid taurine. Photo: zen.yandex.ru
What is taurine in energy drinks? It is an antioxidant that is effective in protecting the body from cancer, increasing endurance and accelerating metabolic processes in the body. The methods of use and harm of taurine have long been known to many people involved in bodybuilding and other strength sports. It speeds up metabolism, increases activity and performance. It is for this reason that the active substance is very popular among athletes and those losing weight.
What products contain it?
Foods that are the main sources of taurine are meat, fish, and especially shellfish. This amino acid is also found in eggs and dairy products. Taurine is synthesized from the amino acids cysteine and methionine, with the participation of vitamin E. The human body obtains these amino acids mainly from animal products. It is not surprising that vegetarians are often deficient in taurine, as well as vitamin B12 and other important substances.
Taurine content in food
Product, 100 grams | Taurine content, mg |
Scallop | 827,7 |
Shellfish | 655,4 |
Octopus | 388 |
Squid | 356,7 |
Oysters | 70,0 |
Pork, hip and thigh | 56,8 |
Veal | 46,7 |
Medium sized shrimp | 39,4 |
Tuna | 39,0 |
Beef | 38,4 |
Frozen cod | 31,0 |
Chicken | 14,5 |
Cow's milk | 2,3 |
Peoples who eat a lot of fish and seafood are distinguished by enviable longevity. This applies in particular to the Japanese. In 2009, an article “Taurine is a factor in Japanese longevity: proven through a global epidemiological study” appeared in an English-language journal on experimental biology. Its authors believe that the high consumption of taurine contained in shellfish is the reason for the long life of the Japanese. Omega 3 fatty acids are also important.
You can get 40-400 mg of taurine per day from food, depending on what is included in your diet. Perhaps this is enough for prevention, especially at a young age. But for the treatment of acute and chronic diseases, you need to take taurine in tablets, capsules or eye drops. Because it is physically impossible to eat enough taurine-rich foods to absorb it in therapeutic dosages.
Are there any analogues of the medicine?
In pharmacies you can buy an analogue of “Taurine” in composition. Taurine acid is the main active ingredient in them. Treatment of eye diseases is carried out with the help of Taufon, Catalina, Quinaxa if Taurine drops are not suitable for the patient.
"Taufon" is prescribed for:
- corneal degeneration;
- senile cataract;
- traumatic cataract;
- cataract, unspecified;
- in case of injury to the eyes and orbit.
A side effect may manifest itself in the form of an allergic reaction. It is prohibited to use the drug if you are allergic to Taurine eye drops. Reviews from patients indicate that doctors recommend using 2 drops 3 times a day for several months. The duration of the course is determined strictly by the doctor. Much depends on the severity of the disease and the individual characteristics of each patient’s body. It should be remembered that self-medication can worsen your health.
"Catalin" is prescribed for senile and idiopathic cataracts. It is prohibited to use the drug if you are allergic to the substance pyrenoxine. Use 2 drops 4 times a day. The duration of treatment is determined by the doctor. Side effects may occur in the form of:
- marginal blepharitis;
- conjunctival injection;
- burning, pain and itching.
It is important to consult with your doctor before use.
Quinax is prescribed by an ophthalmologist for:
- senile cataract;
- traumatic cataract;
- congenital cataract;
- secondary cataract.
Contraindications include:
- increased individual sensitivity to one of the components of the drug;
- It is not recommended to use the drug during pregnancy.
Use 2 drops 4 times a day. Side effects appear as:
- eye irritation;
- eye hyperemia;
- increased lacrimation.
Only after examining the patient, the doctor determines the specific type of medicine that will help cure the disease. Depending on the individual characteristics of each patient’s body and the severity of the disease, the dosage of drops is determined.
What are the benefits of taurine?
The debate about the benefits and harms of this amino acid continues. But still, the benefits of taurine for the body are much greater. The beneficial properties of taurine are undeniable.
For the cardiovascular system
Taurine has the beneficial property of improving blood circulation and metabolism in the heart muscles. This benefits the general condition of the body and improves tone. In addition, scientists believe that taurine acts as an anti-catabolic, a drug that reduces the harm from homocysteine. In a state of stress, taurine acts as a protector for the heart muscles; it binds and blocks catecholamines, which cause overload of the heart muscle cells with calcium ions. It is known that taking taurine counteracts the necrotic processes of the cardiovascular system. It lowers blood pressure and has benefits in the form of strengthening the heart muscle. Its beneficial properties have a beneficial effect on heart rhythm and eliminate arrhythmia.
For the nervous system
Taurine also benefits the nervous system. The fact is that it is a transport component, a neurotransmitter, a compound that ensures the transmission of impulses to the receptor. This beneficial property promotes the functioning of all human organs. This connection provides a timely impulse from the brain.
For visual acuity
With increasing age, the eyes become more sensitive to external influences (sun, light, dust, heat), scientists attribute this to degenerative changes and harm from taurine deficiency. If the taurine content in the tissues of the eye is present in normal quantities, then the visual apparatus is not subject to negative effects. Lack of amino acids provokes dystrophic and atrophic diseases of the organs of vision. Taurine benefits the eyes in the form of rejuvenation, regeneration and repair and normalizes energy balance and strengthens membranes in cells.
Important! Taurine is used for diabetes, the benefits and harms of such therapy are not comparable, the drug promotes intoxication and tissue regeneration, which is extremely necessary for this disease.
For the brain
Taurine has beneficial properties for the nervous system. Its protective property for the brain is especially useful. The amino acid is used for the treatment of neuroses, epilepsy, restlessness and agitation, hyperactivity and seizures. The level of taurine in a child’s brain is 4 times higher than that of an adult. The substance has the property of helping a child learn better and be more focused
The benefit of the amino acid in the ability to restore the energy level of the nerve cell is such that both memory and attention improve (anger, irritability decrease), sleep normalizes
Benefits of taurine for humans
The medical field has long known about the benefits and harms of taurine for humans. A lack of beneficial amino acids leads to serious disturbances in the metabolism, cardiac and nervous systems. A deficiency of the substance leads to a deterioration in overall health, loss of strength, and weakness.
What does taurine help with:
- improvement of metabolism, normalization of weight;
- the use of taurine for hair and skin improves their appearance;
- cancer prevention;
- prevention of ophthalmological pathologies;
- complex treatment of diabetes mellitus and heart failure.
But it is not enough to know about taurine, what kind of substance it is for the body, you need to familiarize yourself with the negative consequences of taking the drug. It helps lower blood pressure, so its use is not recommended for hypotensive people. In addition, energy taurine stimulates the active production of bile.
Alternative drugs
Amino acid analogues are sold only in pharmacies and are intended for medical purposes.
If you want to take a substance for weight loss, then take dietary supplements called “Taurine”. They do not contain additional components. Here are some pharmacy analogues. These are Dibikor and Igrel. There are analogues that are designed for athletes, and they contain a whole range of substances. For example, CGT-10 from Optimum Nutrition. The drug includes glutamine, which has a synergistic effect. Combinations of taurine with creatine and L-Cartinite are good.
Here are a few more products:
- Twinlab Mega Taurine Caps;
- Taurine NOW;
- Taurine Trec Nutrition.
Indications and contraindications
Eye drops with taurine can be used as a prophylactic for increased eye work and increased stress on their structures: on the computer, drivers, teachers, etc. As a means of regeneration and reparation, Taurine can be used as part of complex therapy or as a single agent for the following diseases :
- Corneal dystrophy is a hereditary disease that leads to clouding of the cornea;
- Retinal dystrophy is a disorder in the vascular system of the eye, which can be peripheral or central, congenital or acquired;
- Cataract of any etiology – clouding of the lens;
- Keratitis – inflammation of the cornea of the eye, traumatic or infectious;
- Glaucoma (as an adjuvant) – impaired functioning of the optic nerve due to increased intraocular pressure;
- Post-traumatic recovery – treatment or prevention of possible inflammation;
- Ophthalmoherpes – eye lesions with the herpes virus with the corresponding clinical picture;
- Erosion of the cornea of the eye is damage to the upper layer of the cornea, the epithelium.
In the treatment of glaucoma, Taurine is used together with Timolol drops, taking a break between doses of at least 30-40 minutes. Some patients noted a significant decrease in intraocular pressure due to a decrease in the production of tear fluid, which is an effect of the use of Taurine.
We also recommend that you familiarize yourself with Taufon eye drops in this material.
The main active ingredient has an antioxidant effect, which ultimately, with its constant use, leads to rejuvenation of the visual system as a whole. In addition, taurine is one of the important regulatory substances that has a beneficial effect on the metabolism of carbohydrates, proteins, and hormones.
Contraindications
Since the substance is of almost natural origin, contraindications to its use are minimal:
- Hypersensitivity to the components of the drug and, in particular, to the active substance – taurine. Particular caution should be exercised by persons prone to allergic reactions;
- Childhood and adolescence. The medicine is allowed to be used only after reaching 18 years of age;
- Gestational period (time from fertilization of the egg to the birth of the child), since there is no reliable data on the effect on the fetus.
During pregnancy
The period of bearing a child is not indicated in many instructions as prohibited. At the same time, a reservation is made that use is possible only when absolutely necessary and under the constant supervision of the attending physician.
This contradiction is explained very prosaically - the lack of results on the use of the drug during pregnancy. Like most medications, even if they are eye drops, Taurine may, under certain circumstances, turn out to be the missing drop that will negatively affect the development of the fetus. Therefore, it is better not to take risks, and if you decide to use the drug, be sure to consult your doctor.
For small children
Treatment of children with Taurine according to the instructions is prohibited, and this prohibition is of the same nature as during pregnancy. That is, the lack of reliable data.
However, pediatricians often prescribe an analogue of the drug - Taufon drops, which have the same concentration of taurine as the drops of the same name. At the same time, the age of the children is far from being close to adolescence. This is explained by the fact that the drug has a minimum of side effects.
Taurine instructions for use dosage and method
Solution for intraocular administration
Taurine in the form of a solution for intraocular administration is administered under the conjunctiva in a dose of 0.3 ml once a day.
The course of treatment is 10 days. Repeated courses are carried out after 6–8 months.
Eye drops
Taurine eye drops are used topically in the form of instillations.
Recommended doses and duration of therapy:
- cataracts: 1-2 drops 2 to 4 times a day for 3 months. After 1 month, the course of treatment is repeated;
- dystrophic diseases and injuries of the cornea: 1–2 drops 2 to 4 times a day for 1 month;
- open-angle glaucoma (in combination with timolol maleate or butylaminohydroxypropoxyphenoxymethyl methyloxadiazole): 1-2 drops 2 times a day 15-20 minutes before using a local antihypertensive agent; the course of treatment is 6 weeks, followed by a 2-week break, after which a repeat course is prescribed.
Eye films
The drug in the form of ophthalmic films is used topically by placing behind the lower eyelid.
The film is removed from the contour blister pack (it is advisable to use clean ophthalmic tweezers for this) and, pulling back the lower eyelid, it is placed in the space between the eyeball and the eyelid. After this, the eyelid is released and the eye is held motionless for 30–60 seconds (this is necessary to wet and soften the film).
For corneal dystrophy, the drug is used once every 1–2 days. One course of treatment requires 10 to 15 eye films.
For corneal injuries, films are placed daily (1 piece) for 10 days.
Indications for use
Taurine is not used as monotherapy, but it is included in the treatment of many eye diseases. Pathologies for which drops are prescribed:
- cataracts of various origins (senile, traumatic, metabolic, toxic, radiation);
- dystrophic changes in the cornea;
- retinal dystrophy;
- glaucoma (as a stage of complex therapy);
- mechanical damage to the mucous membrane due to foreign bodies, burns, insect bites.
The product is also used to eliminate eye fatigue. This syndrome can develop with prolonged work at the monitor, increased dustiness of the air, or irritation of the cornea with chemical vapors.
The active ingredient of the drug relieves inflammation and swelling.
Release form and composition
Taurine is available in the following dosage forms:
- solution for intraocular administration: colorless, transparent liquid (1 ml in neutral glass ampoules, 10 ampoules in a cardboard box and instructions for use; 1 ml in neutral glass ampoules, 5 ampoules in blister packs, 2 blister ampoules in a cardboard box packaging);
- ophthalmic films: polymer oval plates with blunted edges, white or white with a yellowish tint, size 9 × 4.5 × 0.35 mm (10 pieces in blister packs, 1 or 3 blister packs in a cardboard box);
- eye drops: transparent, colorless liquid (1.5, 2 or 5 ml in polymer dropper tubes, 1, 2, 4, 5 or 10 dropper tubes in a cardboard box; 5 ml or 10 ml in polymer dropper bottles , in a cardboard pack 1 or 2 bottles; 5 ml in bottles, in a cardboard pack 1 bottle complete with a dropper cap; 5 ml in bottles, 5 bottles in blister packs, in a cardboard pack 1 blister pack included 5 dropper caps).
Each pack also includes instructions for using Taurine.
Composition per 1 ml solution for intraocular administration:
- active substance: taurine – 40 mg;
- auxiliary components: water for injection.
Composition for 1 eye film:
- active substance: taurine – 3 mg;
- auxiliary components: biosoluble polymer (in an amount sufficient to obtain a film weighing 16 mg), potassium dihydrogen orthophosphate, polyethylene oxide.
Composition per 1 ml eye drops:
- active substance: taurine – 40 mg;
- auxiliary components: methylparaben, water for injection, sodium hydroxide solution 1M (until pH 5.0–6.5 is obtained).
Analogs
Taurine has equivalent substitute drugs. If the patient has an allergic reaction to the solution or individual intolerance, analogues are selected that are identical in action and to the intended purpose. All eye drops are intended for adult patients only:
- Taufon is a taurine-based medicine, a colorless transparent liquid. This is a Russian analogue for the treatment of cataracts of various origins. The solution is sold in dropper bottles and disposable plastic ampoules. Prescribed for rapidly progressing dystrophy of the lens and other structures of the eye.
- Oftan Katahrom ─ combined drops, red solution. The drug quickly penetrates the cornea and is included in the restoration processes. In addition to local allergic reactions, it causes systemic phenomena: nausea, shortness of breath at rest, decreased blood pressure, dizziness, hot flashes, pulsation in the temples, and rarely, fainting.
- Catalin is a drug based on pyrenoxine. The main effect is the neutralization of toxic substances that are formed during the breakdown of amino acids. Available in the form of tablets for self-preparation of the solution. The drops turn out to be a rich yellow color. During treatment, it causes the following negative phenomena: inflammation of the eyelids (blepharitis), diffuse damage to the cornea, conjunctivitis.
- Quinax ─ pink or red eye drops. They stop oxidative processes in the lens, tissue degradation, and activate the production of enzymes in the anterior chamber of the eye, which support the functionality of the organ of vision. During therapy, burning, itching, conjunctival discomfort, dryness or lacrimation often occur.
- Khrustalin is a means for the prevention and timely prevention of destruction of eye tissue. It is not a pharmacological drug. Prescribed to people at risk, as well as to those whose work involves eyestrain. The drops have a moisturizing, antiseptic, and soothing effect. If the pathology (cataracts, presbyopia, glaucoma) has already formed and is progressing, Khrustalin is not prescribed.
Taurine analogue drugs are not absorbed into the bloodstream and are safe to use if treatment regimens are followed.
Side effects
Since the main source of taurine is energy drinks, many believe that strong stimulation, slight tremors and irritability are associated with it. And they are deeply mistaken. After drinking a couple of cans of Red Bull or Monster, you are “invigorated” not by taurine, but by caffeine, sugar and other components of the energy drink.
However, caution must be exercised when:
- Kidney disease. Like other amino acids, large doses of taurine can cause some problems in people with kidney disease.
- Pregnancy and breastfeeding. There is not enough information on its consumption during pregnancy or breastfeeding, so avoid its use.
- Bipolar disorder. Some sources claim that a large dose of taurine may worsen bipolar disorder. Therefore, energy drinks are not recommended for people with bipolar disorder.
- Combination with lithium. Taurine can change the amount of lithium in the body. Before using it in combination with lithium, consult your doctor to avoid negative side effects.
What is important to know before using the drug
“Taurine” is an eye drop that is important to use correctly during the treatment process. Before using the drug for eye therapy, it is important to consult a doctor and follow all specialist recommendations. Among them are:
- Read the instructions included in the medicine package.
- Wash your hands thoroughly with an antibacterial solution. This is necessary to prevent eye infection.
- Before using Taurine eye drops, you need to warm the closed bottle in your palms.
- Slightly pull down the lower eyelid and drop drops into the inner corner of the eye. It is important not to touch the cornea with the pipette.
If the patient bought the medicine in glass bottles without special droppers, then they must be purchased separately. It is not recommended to use the pipette several times; it is important to use disposable devices. The exact dosage will be determined strictly by the doctor, after a thorough medical examination of the patient. In frequent cases, it is necessary to instill drops 3 times a day, 2 drops in each eye.
Taurine tablets
In Russian-speaking countries, Dibikor tablets, the active ingredient of which is taurine, are popular. The medicine Kratal for cardiovascular diseases is also produced in Ukraine. It contains taurine, motherwort and hawthorn extracts.
The Centr-Zdorovja.Com website recommends ordering taurine capsules from the USA instead of Dibikor. To get a daily dose of 2 grams of taurine, you need to take 4 tablets of Dibikor 500 or 8 tablets of Dibikor 250. Compare the cost of the daily dose you need in domestic tablets with the price of the same dose of taurine from the USA. The benefit is significant. The savings are worth it to figure out how to order supplements from abroad and receive them by mail.
Taurine tablets help against hypertension and heart failure. They are a healthy alternative to “chemical” diuretics. You can also take taurine for nervousness, depression, epilepsy, and liver diseases.
Taurine, like other amino acids, should be taken on an empty stomach - 20-40 minutes before a meal or 2.5-3 hours after a meal. If taken immediately after a meal, the effectiveness will decrease because most of the active substance will not be absorbed. The therapeutic dosage of taurine is 1.5-3 grams per day. For heart failure, you can try higher doses under the supervision of a doctor. Above on this page there are instructions for use. Re-read the “Side Effects” section in it. Dosages less than 1 gram per day are practically useless.
Patient reviews
People recommend reading the instructions for using Taurine eye drops before using the product. Reviews from patients who have used the drops confirm the fact that the product effectively helps get rid of cataracts. In frequent cases, this disease occurs in older people, since with age-related changes in the body the biochemical composition of the lens changes, but this can be prevented in time. Patients are of the opinion that visual acuity can only be preserved if they consult a doctor in a timely manner. Taurine can be effectively taken not only during the treatment of cataracts, but also for the prevention of diseases. Patients who were found to have recurrent corneal erosion used Taurine. This remedy effectively eliminates lacrimation, discomfort and discomfort in the eye area. According to welders, you can reduce eye fatigue and prevent the development of cataracts with the help of Taurine eye drops, the price of which is no more than 20 rubles.
Contraindications
If you have high acidity and problems with bile, you should not take any action without the advice of a doctor. Also, the drug may cause an allergic reaction if the dose is exceeded. For example, it can cause indigestion and contribute to diarrhea. Pregnant women should definitely stop using this drug.
Reviews and opinions of doctors
Kremenchuk Anatoly Viktorovich, 48 years old, Rostov-on-Don Prescribed the drug Taurine to a patient with mild retinal dystrophy. 2 courses were completed, 2 months long, with a break of 1 month. After the entire treatment, vision improved significantly, the patient was satisfied. This is a truly high-quality product that has a lot of useful properties and is widely used in modern medicine. Karlova Inna Nikolaevna, 52 years old, Novosibirsk Prescribed a course of taking Taurine drops for a person with incipient radiation cataracts. Thanks to timely contact with a specialist, proper treatment and compliance with all the rules, the patient got rid of all problems after six months and lived a normal life. Taurine is an indispensable drug in the treatment of ophthalmic diseases and is valuable for its unique beneficial properties. It is important to always consult a doctor and not self-medicate, especially in such serious cases!
Taurine supplements: reviews and results ^
Compliance with the instructions and duration of taking Taurine in any form is the key to the high effectiveness of the drug, which is expressed in the following:
- Diseases caused by a lack of this acid disappear;
- General well-being improves;
- Additional energy appears;
- Glucose levels and blood pressure are normalized;
- Additional energy appears;
- Weight loss.
Where to get taurine to compensate for its deficiency
- Products: fish and meat - the main source of taurine (per 100 g of raw weight - up to 200 mg of taurine);
- Vegetarians and those who limit meat and fish should pay attention to drugs in pharmacies - Dibikor, Cardio Active Taurine;
- Dietary supplements on the Iherb website: Solgar, Jarrow Formulas, Now Foods, Thorne Research, Life Extension, Source Naturals;
- In sports nutrition, taurine is sold in combination with other amino acids.
Composition and properties
The composition of the drops is very simple. First of all, it contains taurine itself, which acts as the main active ingredient. Its amount is about 40 mg per 1 ml of ophthalmic solution.
Taurine is a substance responsible for regeneration processes in the human body. It promotes the conduction of nerve impulses, improves the properties of cell membranes, and promotes metabolic processes.
In addition to taurine, the medicine contains plain water and the excipient methyl parahydroxybenzoate. Although there are few components in the drug, the medicine has proven itself well, and the benefits of Taurine are undeniable.
Taurine for weight loss
There is information that this biologically active substance promotes weight loss and therefore women are interested in how to take taurine. However, in reality, there is no scientific basis that could confirm that the amino acid is truly capable of burning fat and speeding up metabolism. If you add an amino acid to a high-calorie diet, there is a possibility of aggravating the person’s condition. Positive results can be observed to a small extent when a person who wants to lose weight not only follows a diet, but also leads a sporty, active lifestyle.
Treatment in adults and possible side effects
The dosage of Taurine depends on the purpose of use and the diseases faced by the patient.
Before use, consult a specialist.
If cataracts develop, at the beginning of treatment, use the drug three times a day, three drops, the course of treatment will be from one to one and a half months. Subsequent cataract therapy is almost identical, only two drops must be used.
For traumatic damage to the visual system, dosage is up to three drops, three times a day.
Treatment of glaucoma requires the complex use of medications; taurine acts as an adjuvant.
It is recommended to use it thirty minutes before using the main medications, no more than one drop.
For dystrophic lesions, it is possible to prescribe injections of the drug, once a day, with a volume of 0.3 ml. The duration of the course should not exceed ten days, and the break before re-treatment should not be less than six months.
Varieties
The medicine is produced in several forms. Only the manufacturer differs, but the composition and properties are the same. The price segment may vary depending on the country of origin.
Taurine DIA
The use of Taurine DIA is recommended for various ophthalmological diseases, but it is most often used for cataracts. The drug contains 40 mg of active substance per 1 ml of solution.
The use of Taurine DIO is also justified for corneal injuries and retinal dystrophy.
Taurine Akos
Taurine Akos is a drug whose main active ingredient is also taurine. Excipients, as in Taurine DIAA, are methyl parahydroxybenzoate and plain water for injection. Drops are best used for cataracts, but ophthalmologists also prescribe them for various diseases of the retina and cornea.
Taurine tablets are also used in medicine if it is necessary to influence the body not locally, but systemically. They are used for pathologies of the heart and blood vessels, hypertension, and diabetes.
What foods contain taurine?
Having heard a lot of positive reviews about this component, many will want to purchase it as soon as possible. The biologically active substance can be purchased at a regular pharmacy, or in one of the popular online stores as a dietary supplement. However, there are also natural analogues. Products containing taurine are present in our daily diet. If you wish, you can create a special menu that will include your favorite and very healthy foods. This component can be found in:
- fish;
- mussels;
- crabs;
- eggs;
- milk;
- shrimp;
- beef;
- rabbit;
- cod;
- pork;
- cottage cheese.
Which eye drops are better: Taurine or Taufon
These ophthalmic drugs have similar properties. Both Taurine and Taufon are prescribed as eye drops for ophthalmological diseases; their differences are insignificant. On the contrary, doctors consider them interchangeable, and there is not much difference whether a person uses one or the other. Their main property is to help in the treatment of dystrophy, cataracts and other eye ailments. However, Taurine will still be preferable in cases of senile cataracts. The difference is also visible in the price: Taufon (100 - 140 rubles) is almost 2 times more expensive than Taurine (40 - 60 rubles).
Double Strength
Double Strength Taurine is a double strength product. Each capsule of this dietary supplement contains 1000 mg of taurine in free form.
Now Foods, Taurine, Double Strength, 1000 mg, 100 Veggie Caps
See the price on iHerb Reviews on iHerb
Like the first product, it is sold in thick plastic jars with a protective membrane. It is possible to take a larger or smaller package. Capsules are packaged in 100 and 250 pieces.
The capsule shell is made of vegetable cellulose. The contents are a white, odorless and tasteless substance. In addition to the main ingredient, the composition includes stearic acid.
The product is intended for adults. Before starting the course, it is worth studying the contraindications to taking dietary supplements. There are few restrictions, but they still exist. Pregnant and lactating women should not use Double Strength Taurine. You will have to discard the capsules in case of individual intolerance. Concurrent use of drugs prescribed for hypertension, as well as diuretics, is not allowed. Also, some diseases do not allow this product to be included in the diet. In order not to harm your own health, you should first consult a doctor.
Now Foods, Taurine, Double Strength, 1000 mg, 250 Veggie Caps
See the price on iHerb Reviews on iHerb
Manufacturer's recommendation: take 1 capsule once or twice a day with sufficient liquid. It is better to consume taurine between meals.
Taurine is a semi-essential amino acid that is not part of proteins. It is formed in the body from the amino acid cysteine. In mammalian tissues, Taurine is distributed everywhere - in the heart, retina, skeletal muscles, brain and leukocytes.
It is formed in the body during natural metabolism and actively participates in metabolic processes. A person receives the main amount of Taurine from the outside through food.
The content of Taurine in the body can decrease for various reasons - with age, injury, stress, coronary heart disease, Parkinson's disease, vegetarianism.
For many years, scientists believed that degenerative processes in the brain were irreversible. Recent research shows that brain matter loss is a reversible process!
The amino acid Taurine opens up new opportunities for restoring the structure and function of the brain and allows for more than just symptomatic treatment.
Research shows that restoring Taurine levels in brain cells can reverse neurodegenerative changes.
Taurine increases the growth of new cells in the hippocampus, an area of the brain responsible for learning and memory functions. It activates dormant stem cells, which are capable of developing into several different functioning cell types.
Taurine deficiency impairs brain function by delaying normal neuronal development.
Laboratory studies show that Taurine may help solve this problem. When taurine-deficient brain cells are grown in vitro (outside a living organism) and then Taurine is added, it results in a dramatic increase in the formation of new cells.
This is due to several mechanisms of action, including improved mitochondrial function.
In vivo, Taurine increases the growth of brain cells by activating dormant stem cells.
Taurine also increases the survival of new neurons, leading to larger adult brain cells.
Recent studies have shown that Taurine has unique biochemical properties that trigger the formation of new brain cells.
Animal studies show that Taurine triggers new cells in the hippocampus, the area of the brain responsible for memory, and can lead to dramatic improvements in memory and cognition.
In addition to the growth of new brain cells, Taurine improves neural connections, which help brain cells “talk” to each other. The connections between nerve cells carrying electrical impulses are optimized, thereby supporting memory, cognitive activity, sensations, and thinking processes.
The findings that Taurine has a therapeutic effect that can rejuvenate the aging brain and repair damaged brains are truly revolutionary and are beginning to change the way scientists and neurologists think about the treatment of age-related changes and traumatic brain injury. For many years, scientists believed that brain aging was inevitable and irreversible. But new research has shown that brain cells can regenerate.
In addition to these impressive brain benefits, Taurine also improves heart function and reduces arterial stiffness, and reduces the negative effects of metabolic syndrome.
Taurine levels in the body decline significantly with age, leaving the brain, heart, kidneys and other tissues deprived of this vital amino acid that can rescue dying cells and restore cellular communication.
Experts are beginning to recognize that as people age, many may become deficient in Taurine, which is a serious health threat.
Two other positive effects of Taurine have been identified - its effect on depression and Parkinson's disease.
Standard treatment for Parkinson's disease symptoms involves taking Levodopa (Levodopa is an anti-Parkinsonian drug), which further depletes already low Taurine levels in Parkinson's patients. Therefore, Taurine supplements in the treatment of Parkinson's disease are simply necessary.
Taurine supplements are also important for those who suffer from depression, which is especially common in diabetics because... Chronically elevated blood sugar levels contribute to depression and neurodegenerative disorders.
In a study in rats, Taurine supplementation was shown to improve depressive-like behavior and improve diabetes-damaging neurotransmitter function (neurotransmitters are chemicals involved in transmitting signals between neurons).
Cardiovascular diseases are the leading cause of death among adults. Heart problems cause premature aging and lead to early death.
Scientific research shows that low levels of Taurine worsen poor heart muscle function, and Taurine supplementation may increase lifespan by improving heart muscle function.
Human studies demonstrate the beneficial effects of Taurine on the cardiovascular system.
Taurine has a positive effect in congestive heart failure (the inability of the heart to pump the amount of blood necessary to ensure metabolism in the tissues).
In a study reported in the Journal of Clinical Cardiology, patients with congestive heart failure took either a placebo (dummy drug) or 2,000 mg of Taurine three times daily.
Compared with placebo recipients, patients taking taurine experienced significant improvements in their condition, as measured by cardiac measurements.
In addition, none of the patients taking Taurine worsened during treatment, while this was observed in 29% of those taking placebo.
In another study in patients with chronic heart failure, taking Taurine (3 g per day for six weeks) led to significant changes, confirmed by cardiogram, which showed an improvement in the pumping function of the left ventricle of the heart.
Thus, the assumption is confirmed that maintaining normal levels of Taurine in the body is necessary for the proper functioning of the heart.
The effect of Taurine on metabolic syndrome. Metabolic syndrome is characterized by signs of obesity, high blood pressure, insulin resistance, elevated blood sugar, elevated triglycerides, and low levels of high-density lipoprotein (good cholesterol), which is associated with increased risks of cardiovascular and kidney disease, diabetes, cancer, and ultimately - early death.
Taurine supplements have proven to be extremely effective in reducing the harmful effects of metabolic syndrome.
Studies in mice and rats demonstrate that Taurine leads to improvements in many of the metabolic syndrome factors listed above, including insulin secretion and sensitivity and glucose tolerance.
One study found that taurine-deficient mice developed kidney failure identical to diabetic nephropathy. This suggests that taurine in metabolic syndrome patients may reduce the risk of kidney disease.
Taurine has also been shown in several studies to enhance the beneficial effects of Metformin, an antidiabetic drug that has health benefits for metabolic syndrome.
Human studies have shown how important Taurine is for people with metabolic syndrome, which exacerbates the age-related decline in Taurine levels. Taurine supplementation significantly reduces many of the risk factors faced by individuals with metabolic syndrome.
For example, 3 g per day of Taurine for eight weeks in a group of obese adults produced a 29% reduction in plasma inflammatory markers. and 20% reduction in lipid peroxidation.
Diabetics taking 1.5 g of Taurine per day were not only able to restore Taurine levels to normal, but were also able to reduce platelet aggregation to the level of healthy people. (Platelet aggregation is increased in diabetics, which increases the risk of stroke and heart attacks due to increased blood clot formation).
In addition to heart disease and the risk of strokes caused by aggressive platelet aggregation, diabetics and people with chronically high blood sugar levels have an increased risk of cardiovascular disease due to loss of elasticity and increased stiffness of blood vessels.
Again, treatment with Taurine was able to reverse this dangerous state of affairs. In a study of diabetes and vascular disease in adults with endothelial dysfunction, taking 500 mg of taurine three times daily for just two weeks returned patients to normal levels of arterial stiffness.
Taurine, a still little-studied amino acid, turns out to be able to do the impossible.
Taurine's ability to stimulate the growth of new brain cells opens up completely new possibilities in the treatment of cognitive impairment, and major neurodegenerative diseases such as Parkinson's and Alzheimer's disease!
Our longevity, which is closely related to the health of the cardiovascular system, also depends on Taurine.
Studies in both animals and humans demonstrate Taurine's ability to significantly improve heart and blood vessel function and reduce the harmful effects of metabolic syndrome.
Taurine is found in animal products - fish, seafood, meat and poultry.
Vegetarians, especially strict vegetarians - vegans, do not get Taurine from food at all. Therefore, vegetarianism poses a great harm to health due to the increased risk factors listed above.
Taurine levels in the body decline significantly with age, leaving the brain, heart, kidneys and other tissues deprived of this vital amino acid that can rescue dying cells and restore cellular communication.
Taurine deficiency is a real health threat.
Taurine deficiency can be compensated for by taking additional medication.
Taurine can be purchased >>> HERE .
Taurine is an inexpensive drug and everyone can afford to supplement their diet with Taurine in order to reverse degenerative processes and slow down aging in general.
Links to studies:
https://www.sciencedirect.com/science/article/pii/S1873506115000434 https://link.springer.com/chapter/10.1007%2F978-3-319-15126-7_36 https://www.ncbi.nlm. nih.gov/pubmed/23466467 https://link.springer.com/article/10.1007%2Fs11011-014-9572-x https://www.sciencedirect.com/science/article/pii/S1873506115000434 https://www .ncbi.nlm.nih.gov/pubmed/25833519 https://link.springer.com/chapter/10.1007%2F978-1-4614-6130-2_16 https://www.ncbi.nlm.nih.gov/pmc /articles/PMC4264000/ https://link.springer.com/article/10.1007%2Fs10072-014-1801-x https://www.tandfonline.com/doi/abs/10.3109/00207454.2015.1051046?journalCode=ines20# .VewQ4dErbjQ https://www.europeanreview.org/article/8815 https://link.springer.com/chapter/10.1007%2F978-3-319-15126-7_50 https://link.springer.com/chapter/ 10.1007%2F978-3-319-15126-7_27 https://link.springer.com/article/10.1007%2Fs00726-015-1988-z https://link.springer.com/chapter/10.1007%2F978-3- 319-15126-7_57 https://link.springer.com/chapter/10.1007%2F978-3-319-15126-7_19 https://link.springer.com/chapter/10.1007%2F978-3-319-15126- 7_20 https://www.ncbi.nlm.nih.gov/pubmed/18388409 https://www.ncbi.nlm.nih.gov/pubmed/19239150 https://www.ncbi.nlm.nih.gov/pubmed /23963537 https://archneur.jamanetwork.com/article.aspx?articleid=573523 https://link.springer.com/chapter/10.1007%2F978-1-4614-6130-2_9 https://link.springer. com/article/10.1007%2Fs00726-014-1901-1 https://www.sciencedirect.com/science/article/pii/S0306452214008422 https://www.ncbi.nlm.nih.gov/pubmed/23327111 https:/ /www.tandfonline.com/doi/full/10.3109/00207454.2015.1051046 #abstract https://www.sciencedirect.com/science/article/pii/S0166432815000224 https://link.springer.com/chapter/10.1007%2F978 -3-319-15126-7_45 https://link.springer.com/chapter/10.1007%2F978-0-387-75681-3_3 https://link.springer.com/article/10.1007%2Fs00380-005-0841 -9 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994395/ https://link.springer.com/chapter/10.1007%2F978-3-319-15126-7_51 https://www .journal-of-cardiology.com/article/S0914-5087(11)00010-4/abstract https://link.springer.com/chapter/10.1007%2F978-3-319-15126-7_21 https://link .springer.com/article/10.1007%2Fs00394-013-0586-7 https://ajcn.nutrition.org/content/61/5/1115.long https://dvr.sagepub.com/content/7/4 /300.long https://femsle.oxfordjournals.org/content/226/2/195.long https://link.springer.com/article/10.1007%2Fs10529-015-1846-9 https://www. ncbi.nlm.nih.gov/pubmed/25997235 https://www.sciencedirect.com/science/article/pii/S0304394015000786 https://link.springer.com/article/10.1007%2Fs11064-015-1546-9 https https://link.springer.com/chapter/10.1007%2F978-3-319-15126-7_33 https://link.springer.com/chapter/10.1007%2F978-3-319-15126-7_39
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Impact
The effect of the drug on the body is to accelerate regenerative processes, as noted above. The drug promotes the normal functioning of cells, stimulates metabolic processes, and improves the processes of conducting nerve impulses from organs to the brain.
Taurine eye drops can stop the progression of cataracts and promote wound healing in case of corneal injuries. Although the effect of the drug is great, it will not be possible to restore previously lost vision or eliminate cloudiness on the lens, which must be kept in mind.
Where is taurine found?
Taurine is also found in some foods. For example, meat and fish are its carriers. In addition to heavy foods, it can be found in eggs and milk. Please note that those peoples who have very popular fish in their diet differ from others in good health and long, painless years of life. For example, the Japanese eat sea shellfish. And they live much longer than most Westerners.
But you shouldn’t hope that taurine alone will help you lose weight. This drug works in conjunction with other methods that promote weight loss. First of all, active physical activity and proper diet will serve as the main impact tool for losing weight. And taurine will become an auxiliary link in this process. The benefits of taurine include the following:
- Fast removal of fats;
- Positive reflection on the psychological state;
- Decreased appetite;
- Control of glucose in the body's blood;
- Improving metabolic processes;
Since our body works 24 hours a day, it needs to regularly consume all the necessary substances, which applies to taurine. Negative consequences of taurine deficiency:
- Deterioration of vision;
- Decreased skeletal muscle functionality;
- Excessive anxiety and overexcitability;
- A sharp decline in the immune system;
- Slow development in children;
- High risk of liver and stomach disease;
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