What do Levomycetin drops and tablets help with? Instructions for use

Medicines have become an integral part of human life. Almost every third person on the planet takes some kind of medication. Some people do this directly to correct pathology, while others try to prevent diseases and carry out prophylaxis. In this article we will talk about the drug “Levomycetin” (tablets). You will find out further what this remedy can help with. It is also worth mentioning how to take the medicine in a particular case.

Release form and composition

The medicine is supplied to pharmacies in the form of:

1. Eye drops 0.25%.
2. An alcohol solution with a mass fraction of the active substance from 0.25% to 5%.
3. Capsules and tablets 250 and 500 mg.
4. Liniment 1% or 5%.
5. Long-acting tablets 650 mg.

The active element of the drug "Levomycetin", from which tablets, drops and solution help with many infections, is chloramphenicol, which belongs to the category of antibiotics - amphenicols. The composition of the auxiliary components depends on the form of release of the drug and the manufacturer.

Levomycetin tablets are packaged in blisters of 10 pieces. The cardboard pack contains one blister and instructions for use of the drug.

Indications and contraindications for use

Levomycetin drops are used in ophthalmological practice to treat patients suffering from conjunctivitis, keratitis and other infectious diseases caused by microorganisms sensitive to the action of this antibiotic.

Find out how to choose lenses for glasses here.

The drug is also used for the treatment of infectious diseases in case of ineffectiveness of other drugs.

Mode of application

The doctor usually prescribes 1 drop of the drug in each eye 3 times a day . Drops are drawn from the bottle with a clean pipette.

The duration of treatment with Levomycetin drops is determined by the ophthalmologist individually for each patient. The maximum duration of treatment should not exceed 2 weeks.

Features of application

Longer use of Levomycetin eye drops should be avoided, as there is a possibility of developing hypersensitivity and the emergence of resistant microorganisms.

When visiting an ophthalmologist, patients must inform the doctor about:

• Previous conjunctivitis;
• At the first signs of glaucoma of the eye;
• Dry eye syndrome;
• Eye surgery or laser vision correction within the last 6 months;
• Previous eye injury;
• Current use of other allergy eye drops or eye ointment;
• Wearing contact lenses.

Phacoemulsification of cataracts is an operation that thousands of people undergo every year. You can read about it here.

During the course of treatment with these drops, you should not wear contact lenses. They should also not be worn for 24 hours after treatment is completed.

Levomycetin drops affect the ability to drive vehicles and potentially dangerous mechanisms and can cause temporary blurred vision. Patients should not drive a car or operate moving machinery until their vision is completely restored.

Contraindications

Levomycetin drops are contraindicated in the following cases :

• In case of increased individual sensitivity to the components of the drug and other drugs of the chloramphenicol group;
• Patients suffering from psoriasis, eczema and fungal skin infections;
• Women during pregnancy and breastfeeding;
• Children under 4 months of age.

Pharmacological properties

The drug "Levomycetin" is an antibacterial agent with a wide range of applications. The active component has a detrimental effect on gram-positive and gram-negative bacteria, microorganisms that cause dysentery, typhoid fever, and meningitis. The medicine has bacteriostatic properties.

"Levomycetin" tablets, for which reason they are used in various fields of medicine, help with diseases caused by spirochetes, chlamydia, brucella, hemophilus influenzae and other bacteria. The medication does not have the proper effect on protozoan microorganisms, clostridia, and Pseudomonas aeruginosa. Resistance to the antibiotic "Levomycetin" develops slowly in bacteria, while addiction to other drugs is not observed.

When using drops, the active substance accumulates in the iris, vitreous body, cornea, and “Levomycetin” does not enter the lens. The medication is well absorbed by the body when taken internally, concentrating maximum in the blood after 1-2 hours.

Can these drops be used for children?

The greatest controversy surrounding this drug is the topic of its use in young children: despite the fact that the instructions limit use only in newborns up to 4 months, some doctors and young parents show excessive caution based on the composition of the drug. The main reason why not everyone considers it reasonable to include Levomycytin drops in children's therapy is the presence of an antibiotic in their composition, but its concentration here is to a degree that allows the drug to be used even in newborns, but under the supervision of a doctor

For children over 2 years of age, drops are allowed without any restrictions, only taking into account the sensitivity of the body. This is confirmed by reviews of young mothers

The main reason why not everyone considers it reasonable to include Levomycytin drops in children's therapy is the presence of an antibiotic in their composition, but its concentration here is to a degree that allows the drug to be used even in newborns, but under the supervision of a doctor. For children over 2 years of age, drops are allowed without any restrictions, only taking into account the sensitivity of the body. This is confirmed by reviews of young mothers.

• Anna: “My daughter (3 years old) was given Levomycytin, but they gave it up immediately because the girl began to complain of a burning sensation in her eyes. They attributed it to an individual reaction, since the niece did not experience such sensations, and replaced it with Tobrex.”
• Irina: “My daughter (1 year and 8 months) did not experience any side effects, but we did not see any results from the treatment of conjunctivitis: her eyes began to water and continued to water. As a result, after long discussions with the doctor, they replaced it with another drug.”

Some women mistakenly assume that Levomycytin drops are produced separately for children and adults. This is facilitated by the difference in concentration of the active substance indicated on the bottles presented in pharmacies. Doctors clarify this point:

“Levomitin drops are divided into those that are injected into the eye canals, and those that are intended for instillation into the ear canals. There is no division of the drug into children’s and adults: for newborns, the same solution is used as for children over 12 years old, but in a lower dosage.”

As for the algorithm for using Levomycytin drops in children, the proportion of the solution is calculated based on the child’s weight and the degree of his sensitivity.

• Newborns - up to 6 mg for every 1 kg of weight;
• Infants aged from 2 weeks - up to 12.5 mg for every 1 kg of weight;
• Children over 2 years old - 1-2 drops once.

An opened bottle can be used for 30 days

During use, it is important to ensure its sterility: you should not touch the spout with your hands (even after cleaning them with antibacterial agents), and it is also unacceptable to lean the spout against the surface of the eyeball

Medicine "Levomycetin": instructions for use

Using Levomycetin solution and eye drops

To obtain a solution, the powder is diluted in 2-3 ml of injection water. The dosage and duration of therapy is determined by the doctor according to indications separately for each patient. Injections are given into a vein or muscle tissue. Levomycetin eye drops are injected into the conjunctiva 1 - 2 units 3-5 times a day. Treatment lasts 5-15 days.

How to take the pills

Levomycetin capsules and tablet form are taken orally 30 minutes before meals. Adult patients are prescribed 1-2 tablets 3-4 times a day. The daily volume of the medication reaches 2 g. In difficult cases, it is possible to take 4 g of the drug 4 times a day. In this case, medical monitoring of the functioning of the kidneys and liver, as well as blood composition, is necessary.

The duration of therapy depends on the indications and is about 7 - 10 days. If there are no adverse reactions, the medication can be taken for two weeks if necessary.

Instructions for use of the drug "Levomycetin" for children

For children under 3 years of age, the one-time amount of the product is determined by body weight: 15 mg per kg. Children up to 8 years old are given 150 mg 3-4 times a day. Children over 8 years old should take 0.25 g 3-4 times a day.

Pharmacodynamics and pharmacokinetics

Chloramphenicol is destructive to most gram () and gram (-) bacteria (including strains that are resistant to sulfonamides, streptomycin and penicillin), spirochetes, rickettsia, and some large viruses.
Shows low activity against Clostridium, Pseudomonas aeruginosa, acid-fast bacteria and protozoa.

Resistance to chloramphenicol in microbes develops relatively slowly; cross-resistance to other chemotherapeutic drugs, as a rule, does not occur.

When applied topically, the required concentration is created in the aqueous humor, vitreous fibers, cornea and iris. The drug does not penetrate the lens.

Pharmacokinetic parameters when taking chloramphenicol orally:

• absorption - 90%;
• bioavailability - 80%;
• degree of binding to plasma proteins - 50-60% (in prematurely born
• term infants - 32%);
• Tmax - from 1 to 3 hours.

Therapeutic concentration in the bloodstream remains for 4-5 hours after oral administration. About a third of the dose taken is found in bile; the highest concentration of Levomycetin is created in the kidneys and liver.

The drug is able to cross the placental barrier, its serum concentration in the fetus can reach 30-80% of the serum concentration in the mother. Penetrates into milk.

Elimination time is 24 hours. It is excreted mainly by the kidneys (90%). From 1 to 3% is excreted with the intestinal contents. T1/2 for an adult - from 1.5 to 3.5 hours, in children 1-16 years old - from 3 to 6.5 hours, in children 1-2 days after birth - 24 hours or more (with low weight longer body), on days 10-16 of life - 10 hours.

It is poorly susceptible to hemodialysis.

Contraindications

The instructions for use of the medicine "Levomycetin" prohibit its use for the following diseases and conditions:

• individual non-acceptance of the active component and components of the drug;
• skin pathologies;
• eczema;
• depressed hematopoiesis;
• psoriasis;
• fungus on the skin;
• sore throat;
• acute respiratory infections;
• pregnancy;
• breastfeeding.

The product should not be used together with barbiturates, sulfonamides, cytostatic drugs, Butamide; modifications of pyrazolone. The medicine "Levomycetin" quickly penetrates into mother's milk, which is why it cannot be used during lactation.

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Side effects and what else you need to know

Interestingly, there are practically no side effects caused by Levomycetin. It can only be noted that some patients with hypersensitivity to the active substances developed a rash or itching on the skin, and their eyes experienced irritation. But, in general, the remedy cannot be classified as one that causes serious ailments. Increased tearfulness may also be noted.

The drug has side effects

Levomycetin has few contraindications.

1. The product cannot be used by people who suffer from eczema, psoriasis and fungal skin diseases.
2. Hypersensitivity to substances contained in the product.
3. Sensitivity to drugs belonging to the group of chloramphenicol.
4. These drops should not be used by women who are pregnant or who are breastfeeding. In the latter case, the use of the drug is allowed subject to a temporary refusal to feed the child breast milk.
5. Children under 4 months of age are prohibited from instilling Levomycetin.

Storage conditions

Attention! Levomycetin can impair attention and quality of vision, which means that people working in areas where increased attention is needed, as well as drivers of various vehicles and those responsible for the lives and well-being of other people, should not be prescribed it.

Pregnant women should not use Levomycetin only because the possible risk to the fetus is much higher than expected from the use of this antibiotic - the drug can penetrate the placenta and affect the unborn baby. Although in fact, a thorough study of the effect of this drug on the fetus has not been fully studied. The same applies to the period of breastfeeding. Levomycetin passes into breast milk and, accordingly, into the child’s body. As a result, serious side effects appear in the baby.

The drug is not indicated for children under two years of age

If Levomycetin, or rather, chloramphenicol, which is part of its base, enters the body of a small child in large quantities, then it accumulates in the tissues. The baby’s liver, where toxic substances are neutralized, does not yet function the way it works in adults, which means that cleansing the body is worse. The result may be the so-called “gray syndrome” or “gray child syndrome.” In the presence of this syndrome, the baby’s skin acquires a special color – bluish-gray. At the same time, the body temperature drops, the child does not react to anything, cardiovascular failure and irregular breathing are noted. Unfortunately, the percentage of fatal cases is quite high - about 40%. But in some cases, doctors are able to cope with this syndrome if they call an ambulance in time.

Too much of the drug is harmful

On a note! If too much Levomycetin has been injected into the eyes, it is recommended to rinse them with plenty of clean running water.

Side effect

The drug, when observed in therapeutic doses, is well tolerated by patients. In some cases, injections, tablets "Levomycetin", reviews indicate this, can cause adverse reactions in the body, expressed as follows:

• leukopenia;
• blurred vision;
• hearing loss;
• nausea;
• thrombocytopenia;
• cardiovascular collapse;
• reticulocytopenia;
• allergies;
• confusion,
• diarrhea;
• decrease in hemoglobin;
• hallucination;
• vomiting;
• psychomotor disorders.

About the drug

The substance has high activity against gram-positive and gram-negative bacteria and their strains, chlamydia and other microbes. Once inside the body, the antibiotic disrupts the life processes inside the cell. Resistance to the drug develops very slowly.

Additional components:

• silicon dioxide is an enterosorbent that removes toxins from the body;
• povidone is a detoxifying agent;
• crospovidone is a chemical compound that promotes the release of the active substance from the tablet;
• calcium stearate – stabilizer;
• cellulose - to create a protective shell for tablets and ensure prolonged action;
• macrogol is a polymer that improves intestinal motility;
• titanium dioxide – a filler for tablets that gives a white color;
• iron oxides (black, red, yellow) – food coloring;
• aluminum varnish – food additive, synthetic dye;
• talc is an auxiliary substance for the production of tablets.

Levomycetin actitab, when taken orally, is instantly absorbed into the bloodstream through the gastrointestinal mucosa. Its highest concentration in blood plasma is observed after 2-3 hours. The active effect of the drug in the blood lasts for 4-5 hours. The antibiotic easily penetrates into all liquid media and tissues of the body.

The percentage of chloramphenicol content in the body after administration;

• blood plasma – from 45 to 90%;
• cerebrospinal fluid – from 20 to 50%;
• bile – 30%;
• fetal blood serum during intrauterine development – ​​from 30 to 80%;
• liver – 90%.

Levomycetin is active against the following microbes:

• salmonella;
• shigella;
• Escherichia;
• Proteas and their strains;
• pathogens of meningitis;
• treponema;
• Klebsiella

The antibiotic has no effect on bacteria that are resistant in an acidic environment - staphylococci, enterobacteria, fungi, protozoa.

The drug is excreted from the body within 24 hours by the kidneys (90%), naturally through the intestines (1-3%). During hemodialysis, it is excreted very poorly.

The use of chloramphenicol is effective for infectious diseases of the digestive, urinary and other systems. Levomycetin actitab helps against inflammatory pathologies caused by bacteria that are sensitive to chloramphenicol:

• intestinal infections - dysentery, typhoid and typhus;
• infectious brain damage - whooping cough, meningitis;
• damage to the lymphatic system - tularemia;
• respiratory system infections - pneumonia;
• infectious inflammation of the urinary system - pyelonephritis, chlamydia, cystitis;
• generalized infections – sepsis.

Levomycetin actitab is often prescribed for diarrhea. Tablets in a short time allow you to get rid of symptoms such as loose stools, intestinal upset in the form of putrefactive and fermentative processes (dyspepsia), and flatulence.

Levomycetin actitab is produced in the form of tablets for oral administration. Each tablet is coated with a special film of a light blue hue. In appearance they are oblong in shape, with graphene in the middle. In a cross section, two layers are clearly demarcated. The inside of the tablet is white or with a yellow tint.

The dosage of the dosage form is 250 and 500 mg. One aluminum foil blister contains 10, 12 and 15 tablets. One cardboard box contains from 1 to 6 blisters and instructions for use. Tablets are stored at room temperature not exceeding 25°C, away from sunlight.

Dosage regimens

The drug is taken orally half an hour before meals. The number of appointments is from 2 to 4, depending on the diagnosis. The maximum daily dose of an antibiotic should not exceed 2 g. If the patient is seriously ill and is in hospital treatment, the dosage can be increased to 4 g per day. At the same time, he must be under constant supervision.

The duration of the antibacterial course is 8-10 days.

Levomycetin actitab is prescribed orally for diarrhea. It is important to swallow the tablet whole, without chewing, and wash it down with plenty of water. Diarrhea is almost always accompanied by nausea, abdominal pain, and vomiting. Therefore, it is better to take the drug an hour after eating.

For diarrhea, the maximum course of treatment is 7 days. If there are blood impurities in the stool, then the antibiotic continues to be taken for 15 days.

Main contraindications for prescribing an antibiotic:

• children under 3 years of age;
• hypersensitivity to an antibacterial drug;
• pathology of hematopoietic organs, bone marrow diseases;
• severe kidney and liver dysfunction;
• intermittent porphyria - a genetic disease, a disorder of hemoglobin synthesis;
• skin diseases - fungal infection, eczema, psoriasis;
• cellular disorder of the synthesis of fatty acids and proteins, which leads to hemolytic anemia;
• pregnancy and lactation period.

In case of an overdose of the drug, negative side effects for the body often occur. Since chloramphenicol penetrates everywhere, symptoms of poisoning appear in almost all organs and systems. The most pronounced signs of overdose:

• irritation of the oral mucosa, severe nausea, dyspeptic disorders, dysbacteriosis;
• mental disorders, nervous and emotional tension, irritation, dysfunction of the sensory organs, hallucinations, headaches;
• allergic manifestations - skin itching, rashes, redness, peeling, urticaria, angioedema;
• violation of the quantitative composition of the blood - decrease in red blood cells, platelets, leukocytes, hemoglobin.

The antibiotic is extremely toxic when taken orally and can cause severe side effects. Therefore, it is not prescribed for foodborne infections and functional gastrointestinal disorders, for infants, people weakened by chronic diseases, and elderly patients.

The most dangerous complication when taking an antibiotic, which can lead to death, is irreversible aplastic anemia. This is the inhibition and complete cessation of the formation of blood cells in the bone marrow.

Subjective symptoms of drug overdose:

• loss of strength and body temperature;
• pale skin color with a gray tint;
• arrhythmic breathing;
• lack of reactions to external stimuli;
• development of cardiovascular failure.

Levomycetin actitab helps to achieve a rapid therapeutic effect in severe infections. It is included in the list of vital and essential medicines. But the drug cannot be taken independently, without a diagnosis and recommendations from a doctor. This is due to its toxicity, which poses a serious health threat.

To treat diarrhea caused by a bacterial infection, a gastroenterologist may prescribe Levomycetin Actitab to the patient. The drug has an antibacterial effect, due to which the patient’s digestion process quickly stabilizes. The frequency of medication and dosage are selected taking into account the patient’s age and the course of the disease.

The therapeutic effect of the drug is provided by the substance chloramphenicol (250/500 mg per tablet). There is also a release form such as capsules (250 mg or 500 mg), in which the action of the antibiotic is the same element.

The composition of Levomycetin is supplemented with povidone, calcium stearate, macrogol and other components that contribute to the release of the active element and restoration of the gastrointestinal tract.

The tablets are packaged in cellular contour blisters, 1-5 in a cardboard pack. Capsules are also placed in blisters and cardboard boxes - 20 pieces per package.

Pharmacology

The drug refers to drugs that inhibit bacterial activity in the body. This is achieved by disrupting protein synthesis in the cells of pathogenic bacteria. Levomycetin is a broad-spectrum antibiotic.

The activity of the pharmacological drug is manifested in relation to:

• Streptococcus.
• Shigella.
• Salmonella
• Coxiella burnetii.
• Burkholderia pseudomallei.
• Klebsiella pneumoniae.

They also act on other pathogenic strains of bacteria. The action of the antibacterial drug is ineffective against acid-fast, anaerobic bacteria, enterococci, fungi and protozoa.

The active component very quickly reaches its maximum concentration in the blood. After just 1 hour of taking the tablets, the number of pathogenic bacteria in the tissues decreases. Chloramphenicol is effectively distributed in liquids; in a therapeutic dose, it remains in the blood for up to 5 hours, continuing its effect on bacteria.

The time it takes for the antibiotic to leave the body is 24 hours. More than 90% of the active element is excreted by the kidneys, and up to 3% of chloramphenicol is excreted through the intestines with feces.

Levomycetin is a popular antibiotic. It is active against most pathogens of acute intestinal infections. But due to the high risk of side effects, Levomycetin for diarrhea can only be prescribed by the decision of the attending physician.

Levomycetin for diarrhea is used if stool disorder is caused by the activity of pathogenic bacteria:

• salmonella;
• shigella;
• streptococci;
• some staphylococci;
• chlamydia;
• pseudomonas;
• Proteus and a number of others.

But this antibiotic is powerless against clostridia, Pseudomonas aeruginosa, strains of staphylococci resistant to methicillin, protozoa, fungi and acid-fast bacteria.

Once in the body, Levomycetin is concentrated mainly in the liver and kidneys, but is also present in bile and cerebrospinal fluid. The kidneys and gastrointestinal tract are involved in excretion, which causes possible side effects.

Despite the fact that Levomycetin is a potent antibiotic, it helps with diarrhea only indirectly, destroying the causative agents of the disease. Levomycetin does not have an astringent effect during diarrhea, does not slow down intestinal motility or the production of enzymes in the stomach, and does not have any other properties that could somehow affect the course of diarrhea.

Levomycetin is not used for poisoning. The action of a bacteriostatic antibiotic is aimed at destroying the cells of pathogenic bacteria. It does not affect toxins, heavy metal salts, or radionuclides that cause poisoning.

It is worth distinguishing between an intestinal infection and food poisoning. The symptoms of these pathologies are similar; OCI can also occur after consuming certain foods that contain pathogens.

Like food poisoning, the infection is accompanied by diarrhea, vomiting, diarrhea, and fever.

But the deterioration of the patient’s condition is caused by the activity of pathogenic microorganisms, and not by the poisons contained in the food.

• Lavomycetin;
• Potato starch;
• Low molecular weight medical PVP;
• Calcium stearate.

For adults

Price and analogues

"Levomycetin" can be replaced by the following antibiotics, which have a similar mechanism of action: "Fluimucil", "Neomycin", "Gentamicin", "Baneocin", "Sintomycin", "Fucidin". The analogue “Levomycetin Actitab” is also popular. What does this drug help with?

The main indication for use is bacterial infection. Patients leave good reviews about the eye drops “Levomycentin-Acri”, -AKOS, -DIA. You can buy 250 mg children's tablets for 18 rubles. Levomycetin capsules for adult patients in a dosage of 500 mg cost 25 rubles. The price of eye drops is 35 rubles.

About the drug

Levomycetin® is an antibacterial agent with a wide spectrum of bacteriostatic effects, realized due to the active inhibition of peptidyl transferase and disruption of the process of protein synthesis by bacterial cells. Staphylococci, streptococci, pneumococci, enterococci, Escherichia coli, Haemophilus influenzae, salmonella, Shigella, Klebsiella, serracia, yersinia, proteus, gono- and meningococci, rickettsia, spirochetes, shigella, chlamydia.
Levomycetin® has virtually no effect on acid-fast pathogens, clostridia, Pseudomonas aeruginosa, and protozoa.

• The drug can be used to treat infections caused by strains of bacteria resistant to penicillin, streptomycin and sulfonamides.
• It should also be noted that the antibiotic has rapid and complete absorption in the gastrointestinal tract and high bioavailability when taken orally.

Due to the effectiveness of the drug against many pathogens of acute intestinal infections (AEI), chloramphenicol was previously used quite often for diarrhea in adults, however, at present, it is practically not used for AEI.

This is due to two main reasons. Firstly, despite the widespread myths in everyday life about its harmlessness, chloramphenicol is a rather toxic antibiotic. Treatment with this drug often leads to the development of undesirable effects, in particular, the drug inhibits the hematopoietic function of the bone marrow.

Secondly, due to the frequent self-medication of patients with chloramphenicol tablets for diarrhea, many strains of bacteria have acquired resistance to this drug.

Taking chloramphenicol actitab for diarrhea has long been considered an extremely popular method of treatment, but many patients preferred not only to prescribe the antibiotic themselves, but also to take it incorrectly, drinking chloramphenicol for 1-2 days and stopping taking it.

It should also be noted that most acute intestinal infections are of viral etiology, so taking chloramphenicol for children and adults with diarrhea may not only be inappropriate, but also dangerous. While taking antibiotics, the normal intestinal microflora is inhibited, therefore, with a viral acute intestinal infection, chloramphenicol can only worsen the patient’s condition.

Answering the question: does chloramphenicol actitab help with diarrhea, it should be noted that the antibiotic can still be used for a generalized form of salmonellosis or for shigellosis caused by Shigella Sonne.

However, even in this case, chloramphenicol is not the drug of choice and should be used only after obtaining cultures for the sensitivity of the pathogen to the antibiotic.

Levomycetin is a broad-spectrum antibacterial drug with a pronounced bacteriostatic effect. Many gram-positive and gram-negative microorganisms are sensitive to the antibiotic - chlamydia, spirochetes, brucella, staphylococci, streptococci and many others. The action of Levomycetin is based on the ability to inhibit the synthesis of pathogenic microorganisms, which ultimately leads to their death.

The drug is available in the form of round tablets, white or light yellow. One tablet contains 0.25 or 0.5 g of the main active substance - chloramphenicol.

Our article is a kind of instruction for use of tablets for diarrhea “Levomycetin”. That is why the first thing to start with is a story about what this drug is. Levomycetin is a broad-spectrum antibiotic, these tablets are very effective, including against diarrhea, but only if the ailment is caused by bacteria and microorganisms, for example, in the case of dysentery, salmonellosis and most other intestinal infections.

However, we must not forget that such a pathogen does not always occur in a disease. Sometimes loose stools are caused by viruses, fungi, helminths; diarrhea can be the result of diseases of the gastrointestinal tract. In all these cases, the answer to the question “Can I take Levomycetin for diarrhea?” will be negative. Such treatment will not only not relieve you of your illness, but will also worsen the condition due to a fairly large number of side effects.

After the above, it remains to add that any treatment should be carried out only under the supervision of a doctor. If he determined that bacteria are the cause of the illness, then using Levomycetin for diarrhea in adults would be the right choice.

A detailed article on the choice of remedies for diarrhea in adults is available on our website.

We have already figured out that exceeding the dosage and uncontrolled use of the drug can end very sadly. This is why the doctor should tell the patient how to take Levomycetin for diarrhea, based on the age, condition and weight of the sick person. However, it happens that leaflets with prescriptions are lost, and it is for such cases that we will tell you how to take Levomycetin tablets for diarrhea.

What you need to know

• Treatment with this antibiotic will help if it is started within the first hours (maximum, 24 hours) after the onset of symptoms of diarrhea
• A very important condition for therapy with this medicine is taking the drug at regular intervals.
• Typically, a course of antibiotic treatment lasts from five days to two weeks. However, if the diarrhea ends earlier, the dosage of the antibiotic can be reduced. Of course, this aspect is agreed upon with the attending physician.

For adults

Adults take the medicine one tablet every five to six hours. The maximum effect will be achieved if treatment occurs one hour before or two hours after meals (the food rule applies to all antibacterial drugs that you will have to deal with). For mild forms of diarrhea, the dosage of the active substance in one tablet should be a quarter of a gram, for severe conditions - half a gram. The daily maximum is 4 grams of active ingredient.

The dosage of chloramphenicol for diarrhea in children is calculated based on the weight and age of the baby. If the child is over three years old and weighs more than twenty kilograms, he takes 12.5 mg of antibiotic every six hours, or 25 mg every twelve hours. If the disease is severe, the dosage is increased to 75 mg.

Patient opinions

The main reviews of Levomycetin solution and tablets are related to the use of acne medication. Individuals who have used this acne treatment indicate that their skin cleared up within a couple of days. To combat acne, a mash is prepared for external use, which includes calendula tincture, Aspirin and Levomycetin.

Patients also leave positive reviews about eye drops. They confirm the effectiveness of the product, noting its low price. Side effects are discussed in isolated cases.

Treatment method for conjunctivitis

• nausea;
• vomit;
• allergic reaction;
• diarrhea.

When used externally - either in its pure form (if we are talking about a solution) or as part of a mash (for example, a mash containing Aspirin, Levomycetin and calendula tincture) - the product copes with acne within a couple of days.

There are no less good reviews about Levomycetin eye drops. Despite its low cost, the drug gives quick and in the vast majority of cases 100% results.

Step 1. First of all, when the main signs of the disease appear, you should still make an appointment with a doctor. The fact is that the eyes turn red, itch and even fester in almost any form of the disease, of which there are three.

First, visit your doctor

1. In the viral form, symptoms can be observed on one or two eyeballs at once. This is a contagious and difficult to treat form, treatment usually lasts about 3 weeks.
2. With the bacterial form, the eyes are not only red, but also fester. In this case, it is best to buy a bottle of Levomycetin for treatment.
3. With allergic conjunctivitis, usually, in addition to the main ones, other symptoms appear, for example, nasal congestion. As a rule, you can cope with allergies on your own. True, Levomycetin is useless here - antihistamines are needed.

Is conjunctivitis contagious?

The doctor will help you choose treatment

Step 3: The infected eye should be cleaned regularly

It is important to use clean tissues every time, and you should constantly wash your hands after touching your eyes to avoid spreading the infection to the other eye or passing it on to others.

Use clean napkins

Step 4

It is important to put medications in your eyes. For bacterial conjunctivitis, Levomycetin is still considered one of the best drugs

It is able to quickly not only eliminate symptoms, but also destroy pathogenic microflora. By the way, Levomycetin is sold without a prescription, despite the fact that it is an antibiotic.

Apply eye drops

Step 5. If a person wears contact lenses, it is recommended to stop using them for the period of treatment. Bacteria can settle on lenses and negate all treatment attempts, especially if the immune system is weak enough.

Avoid contact lenses for a while

Levomycetin drops are inexpensive, effective and easy to use, and have virtually no side effects. That is why they are preferred by most ophthalmologists when choosing treatment tactics for conjunctivitis and a number of other eye diseases

But it is important to remember that Levomycetin is an antibiotic, and should never be abused. If after several days of unauthorized use of drops there is no improvement, it is important to consult a doctor as soon as possible

Indications for use

Instructions for use, which are included in the package, indicate that treatment with suppositories is indicated for:

• vaginitis;
• colpitis;
• cervicitis, and other vaginal diseases caused by harmful bacteria.

The medicine can also be used as a preventive measure after surgery, installation of a uterine device or abortion.

Syntomycin suppositories also cope well with various intestinal infections.

Sometimes doctors prescribe medication for the treatment of cystitis, as an additional therapy. This is due to the ability of the antibiotic to penetrate through the wall of the intestine or vagina into the bladder.

How to be treated

Before starting to use the product, you should definitely consult a doctor. The course of drug therapy usually lasts from 7 to 10 days. This time is usually enough to eliminate the bacterial disease.

In special cases, the treating doctor may increase the treatment period if, 5 days after the first course of using Synthomycin suppositories, it was not possible to completely get rid of the infection.

Suppositories should be used once or twice a day, 1 pc., before bed and in the morning. In more complex forms of the disease, the daily number of suppositories can be increased to 4 pcs.

It is treated according to the same scheme, but only after communication with a specialist. After all, each case is individual.

Before putting the drug into the vagina or anus, you should perform water hygiene procedures for the perineum, and also wash your hands well.

Overdose symptoms

Nausea and vomiting may be signs of drug poisoning. A toxic overdose is considered to be a level of Levomycetin above 25 mcg/ml. Symptoms include aplastic anemia, thrombocytopenia, and increased serum iron levels.

If the dose of antibiotic is exceeded, treatment is suspended, and the patient is given gastric and intestinal lavage with activated charcoal. In case of massive overdose, a blood transfusion is given.

Premature and newborn babies may develop “gray” (or cardiovascular) syndrome: due to a lack of liver enzymes, chloramphenicol accumulates in the body, which has a toxic effect on the myocardium. Symptoms of overdose are bluish-gray skin tone, low body temperature, irregular breathing, cardiovascular failure, lack of reactions. The risk of death reaches 40%, so it is extremely important to strictly adhere to pediatric dosages.

Spectrum of action of the drug

The high bacteriostatic activity of the drug makes it effective in combating a large number of disorders.

The tool is capable of:

• invade through the cellular barrier and enter various organs and systems;
• the drug is capable of destroying many microbes, it does not allow them to multiply, disrupting their cell membrane and suppressing protein synthesis;
• the chloramphenicol base accelerates cell regeneration, therefore the product is effective in the treatment of burns and trophic ulcers, applied externally, the product does not enter the bloodstream, the local effect on the body lasts about six to twelve hours.

Sometimes redness of the skin and an allergic rash appear, in which case it is necessary to reduce the dosage or abandon the therapeutic agent altogether. The drug cannot be used for more than two weeks, as it is carcinogenic and highly toxic. The most optimal use is once a day.

Indications for use

Levomycetin belongs to powerful antibacterial agents

, stopping internal inflammation and eliminating infectious processes in the body. Like many antibiotics, it is taken in courses.

Indications for use are the following infectious diseases:

• pneumonia;
• dysentery;
• pathologies of the visual system: blepharitis, keratitis;
• inflammatory processes of the hearing organs: otitis media;
• meningitis;
• brucellosis;
• salmonellosis;
• food intoxication.

In practice, the drug is often used to treat otitis media accompanied by purulent discharge, as well as to eliminate bacterial rhinitis.

Levomycetin is often prescribed for repeated vomiting and diarrhea (up to 10-16 times a day) lasting more than 2 days. In addition, it is advisable to use an antibiotic if:

• vomit contains impurities of blood and bile;
• the patient's condition is characterized by prolonged intoxication;
• elevated temperature continues for more than 2 days;
• other drugs have not shown effectiveness, including sorbents.

The presence of bacteria in the intestinal system can also be indicated by purulent streaks and blood in the feces. In these cases, the use of chloramphenicol is considered mandatory.

An ointment based on it “Levomekol” is prescribed for skin infections of a bacterial nature.

, bedsores, boils, trophic ulcers, wound infections, for the treatment of cracked nipples in women during lactation.

Cautions for the use of alcoholic chloramphenicol

You can purchase chloramphenicol alcohol preparation at a pharmacy kiosk; a doctor’s prescription is not required to purchase it. The product is intended for external use only; the antimicrobial medicine prevents the development and increase in the number of microorganisms.

Psoriasis

There is a list of contraindications for which the use of the drug is contraindicated:

• serious skin diseases, such as eczema and psoriasis, are a categorical ban on the use of the medicinal solution; when using the product, there is a sharp drying of the skin and a deterioration in the patient’s condition;
• childhood is also a reason that does not allow the use of the solution; in children under twelve years of age, chloramphenicol alcohol cannot be used;
• for symptoms of fungal diseases, drug therapy is prohibited;
• While expecting a baby or breastfeeding, a woman should not use the drug;
• In case of serious liver and kidney diseases, the use of alcohol-based products is prohibited.

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It is important not to forget the fact that the medicine can provoke an allergic reaction. This manifests itself in the form of swelling, redness, rash and itching. In this case, the medicine is no longer used and a specialist is consulted.

Molecule structure

In nature, one is most often found ( 1R,2S,5R

)-enantiomer (see bottom left in the figure). The remaining 7 stereoisomers:

In naturally occurring compounds, the isopropyl group trans

-oriented towards the methyl and alcohol group (see figure):

All 3 bulky groups in the “chair” conformation are located in the most distant equatorial positions from each other, which makes (-)-menthol and its enantiomer the two most stable isomers out of 8 possible.

There are 2 crystalline forms of racemic menthol with M.P. 28°C and 38°C. Pure (-)-menthol has 4 crystalline forms, the α form being the most stable.

Levomycetin for cystitis

As mentioned above, Levomycetin can be prescribed to treat infections in the urinary organs. The drug for inflammation of the bladder provides a therapeutic effect due to its antimicrobial properties.

The spectrum of action of the drug is quite extensive

The spectrum of action of the drug is quite extensive. It is used to fight infections that often cause cystitis. Namely for staphylococci, chlamydia, streptococci.

The active substance of the drug is capable of neutralizing pathogens that are resistant to antibiotics of the penicillin and streptomycin group.

The drug is quickly absorbed into the blood after administration. The action lasts for 6 hours.

Chemical properties

Levomenthol, a levorotatory isomer of menthol, is an important secondary metabolite of Lamiaceae plants. The substance is isolated artificially from essential peppermint oil.

According to its physical properties, it is transparent crystals that begin to melt upon reaching room temperature. The substance is highly soluble in ethyl alcohol, hexane, acetic acid, ether, acetone, chloroform, and slightly soluble in water. Molecular mass = 156.3 grams per mole.

The chemical and physical properties of menthol isomers are similar; Levomenthol is most often used in medicine. It is added to the farm. over-the-counter drugs, cosmetics; used in the food industry as a flavoring agent and in perfumery.

special instructions

To avoid serious complications of overdose, some manufacturers indicate in the instructions for Levomycetin that the medicine should not be given to children under 1 year of age.

With great caution, the drug is prescribed to patients who have recently undergone radiation therapy or treatment with cytostatics. If possible, the medicine is not recommended for use in people with impaired liver or kidney function. Long-term antibiotic treatment should be carried out under the strict supervision of a physician .

During therapy with Levomycetin, avoid drinking alcohol, since when combining chloramphenicol with ethanol, the patient may experience convulsions, nausea, vomiting, hyperemia and a reflex cough.

The drug does not have a direct effect on the function of the cerebral cortex, but in order to avoid side effects from the central nervous system, experts advise avoiding driving and working with complex mechanisms. Due to its high toxicity, the antibiotic is not recommended for use in the treatment of common infections and colds.

Scope of application of alcohol-based chloramphenicol

Streptococci

The drug with chloramphenicol is used for various types of diseases; it is effective against the following microbes:

• streptococcus;
• salmonella;
• chlamydia;
• spirochetes.

Levomycetin is an antibacterial drug, so it cannot affect viral and bacterial organisms. The product effectively affects only the simplest organisms. For external use, an alcohol solution of chloramphenicol is used. This is a kind of antibiotic that effectively affects the cause of skin rashes.

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When acne appears due to a hormonal imbalance, alcoholic chloramphenicol with Trichopolum is widely used. No less effective will be a remedy prepared by mixing a solution of calendula, salicylic alcohol, boric acid and alcohol-based chloramphenicol. The effect will appear only with regular use of the drug for one week. After using the product, the skin needs additional hydration. In addition to its therapeutic effect on skin diseases, the product helps to cope with the tendency to sweaty feet. Even after wearing closed shoes for a long time, an unpleasant odor will not appear.