Tsipromed eye drops: instructions and contraindications for use, analogues

Tsipromed drops belong to the group of antimicrobial (antibacterial) agents. Used in ophthalmology and otorhinolaryngology. The mucous membranes of the eyes and the surface of the eardrums are very sensitive to various pathogens. When bacteria act on the membranes, their integrity is disrupted, which leads to inflammatory processes, which are often complicated by the formation of pus. It is in such cases that doctors prescribe antibacterial agents.

Release form and composition

Tsipromed eye drops are available in the form of a solution. The medicine is bottled in plastic bottles, which are equipped with a convenient dispenser. The bottle is equipped with a cap with a first opening control. Each bottle is placed in a cardboard box along with instructions for use.

The active substance is ciprofloxacin, but the drug also contains additional substances - sodium chloride, hydrochloric acid, purified water and others.

Clinical and pharmacological group

Antibacterial drug for local use in ENT practice

Ear drops 0.3%

in the form of a transparent, viscous, colorless to colorless solution with a slightly yellowish tint.

Excipients: benzalkonium chloride, lactic acid, propylene glycol.

10 ml - plastic dropper bottle (1) - cardboard packs.

Indications for use

Tsipromed is used only topically for the treatment of infectious pathologies of the eye and its appendages. The main indications for use are the following diseases:

• conjunctivitis;
• keratitis and uveitis;
• blepharitis and other eyelid diseases;
• dacryocystitis;
• eye injuries and surgical interventions on the organs of vision.

The appropriateness of using a drug for a particular eye disease is determined by the attending physician.

You can start using the drug only as directed by your doctor. You should not self-medicate.

Indications: when will Tsipromed help?

Ophthalmologists prescribe Tsipromed for the treatment of the following infections:

• acute/subacute conjunctivitis;
• keratitis;
• anterior uveitis;
• blepharitis;
• dacryocystitis;
• other inflammatory lesions of the eyelid and eyeball.

Tsipromed - quick help for eye inflammation.

The drug is also used to prevent purulent complications in injuries and operations on the organ of vision.

Irina, 36 years old:

“In the summer, my husband severely damaged his cornea when handling an angle grinder carelessly. Then the ophthalmologist prescribed him Kornergel for rapid healing of the mucous membrane and Tsipromed for the prevention of purulent complications. Improvement occurred already on the third day of treatment: the husband stopped complaining of severe pain in the eye, and lacrimation decreased.”

Method of administration and dosage

The drug is instilled into the eyes up to 8 times a day, at approximately equal intervals. The solution should be dripped into the conjunctival sac, after first pulling the lower eyelid with your fingers.

If the cause of the disease is Pseudomonas aeruginosa, then eye drops should be applied more often - up to 12 times a day. The course of treatment can last up to 3 weeks.

Eye drops are also common in cases of dacryocystitis. In this case, procedures can be carried out every hour. For eye injuries, it is enough to instill the solution 5-6 times a day. After operations, it is recommended to use the drug 4 times a day. The course of treatment can be a month.

During pregnancy and breastfeeding

The drug is prescribed with caution to pregnant women at all stages of gestation and nursing mothers. Tsipromed can only be prescribed when there is no alternative to such treatment. Before using the medicine, the doctor weighs all the risks for the expectant mother and child.

If it is necessary to prescribe it to pregnant women, the doctor calculates the dosage of the drug individually. It is usually recommended to apply eye drops no more than 5 times a day.

Use in children

The medicine is not intended to treat children under one year of age. But in exceptional cases, the doctor may prescribe Tsipromed for a young child. Treatment in this case takes place under the constant supervision of a specialist.

Children over one year old receive 1 drop of the medicinal solution several times a day. The frequency of use is determined by the doctor, depending on the severity of the disease.

If the baby suffers from dacryocystitis, then before and after instilling Tsipromed, the area of ​​the lacrimal canal is massaged with your fingers.

Use in pregnant women and children

The drug is contraindicated during pregnancy and breastfeeding, as the antibiotic penetrates into the blood and breast milk. If during the feeding period the drug cannot be replaced with an analogue, feeding is stopped for the duration of treatment. At this time, to maintain lactation, milk is expressed. Resume 4 days after stopping the drops (this time is enough for the drug to be eliminated from the body).

According to the instructions, ear drops are prohibited until the age of 15; until this age, its analogues are used. For children, eye drops are used upon reaching 12 months; the dosage and duration are determined by the pediatrician. Only a doctor can tell you whether the drug can be given to a child.

Side effects and overdose

When treated with Tsipromed, various side effects may occur. The most frequently recorded patient complaints are:

• severe burning and redness of the mucous membrane;
• itching of the eyelids;
• feeling of sand getting into the eye;
• dry skin and crust formation on the eyelids;
• lacrimation;
• deterioration of visual acuity;
• blurriness of objects before the eyes;
• development of superinfection.

Particularly sensitive people may experience dyspeptic symptoms - abdominal pain, nausea and vomiting. Allergic reactions, in particular dermatitis, are often observed.

Typically, side effects are short-lived and disappear after a while. If unpleasant phenomena continue for too long, we can talk about intolerance to the drug.

When using eye drops in therapeutic doses, overdose is excluded. If the recommended dosage is exceeded, all side effects intensify. In this case, it is necessary to rinse your eyes with running water.

If the drug is accidentally ingested, nausea, vomiting and diarrhea may occur. Treatment boils down to taking adsorbents and drinking plenty of fluids.

If any side effects occur, you should inform your doctor. In many cases, the treatment regimen has to be revised.

Possible adverse reactions

Some varieties of staphylococci are moderately resistant to the solution, so large doses of the drug are required to suppress them. This can provoke local and general undesirable reactions of the body, the most common of which are:

• dizziness;
• fear of bright light;
• redness of the protein membrane;
• temporary blurriness of the “picture”;
• sensation of the presence of a foreign body;
• burning;
• excessive uncontrolled lacrimation;
• swelling of the eyelid;
• spots on the cornea;
• absent-mindedness;
• unpleasant taste in the mouth.

If adverse reactions are detected, it is necessary to interrupt the instillation of Tsipromed and consult an ophthalmologist.

Patients often complain of dizziness while receiving treatment.

In case of overdose or use of eye drops orally, the following are possible:

• attacks of nausea and vomiting;
• fainting conditions;
• migraine;
• feelings of anxiety.

Since there is no antidote for the drug Tsipromed, if the drug gets into the stomach, it is enough to rinse and take activated charcoal.

Some microorganisms are resistant to Tsipromed, so an antibiotic is prescribed based on an examination and study of exudate from the eyes, which is carried out to clarify the type of bacteria.

Dangerous swelling of the sclera of the visual organ is conjunctival chemosis.

An overdose of the drug may cause a feeling of nausea

Find out why chorioretinitis of the eye is dangerous from the article.

Analogs of Tsipromed eye drops

In pharmacies you can find a number of analogues of Tsipromed at different prices. You can replace the original drug with an analogue only with the agreement of your doctor. Before using any medicine, you should carefully study the instructions for use.

Sulfacyl sodium

A broad-spectrum antimicrobial drug that is used for conjunctivitis, keratitis and other diseases of infectious origin. It acts locally, and in small quantities enters the bloodstream through the inflamed mucosa.

Contraindications include intolerance to sulfonamides. The drug is prescribed with caution to allergy sufferers.

When using the drug, there may be redness of the mucous membranes of the eyes and eyelids. Sometimes there is a short burning sensation and a feeling of a foreign body entering the eye.

Levomycetin drops

This is a broad-spectrum antibacterial drug that is used for the prevention and treatment of various bacterial infections. Levomycetin drops are recommended to be instilled into the eyes for conjunctivitis and blepharitis; they help well with barley on the eye.

Children are prescribed this drug for dacryocystitis. In this case, the baby’s eyes are treated up to 6 times a day, each time gently massaging the area of ​​the tear duct. The drug is often prescribed for eye injuries of various etiologies and after surgery on the organs of vision.

Levomycetin drops are very cheap. The price of this drug is not higher than 10 rubles. But despite this, the drops are quite effective and help quickly cure eye diseases.

Tsiprolet

This broad-spectrum antibacterial drug is prescribed for bacterial eye diseases. In the acute period of the disease, the drug can be used 5-6 times a day. Then the frequency of use of the medicine is reduced and the eyes are treated only 3 times a day.

The drug is prescribed to children and pregnant women with great caution, as there is a possibility of developing side effects.

For conjunctivitis or stye on the eye, the doctor may prescribe Tsipromed drops to the patient. This is a broad-spectrum drug that has a detrimental effect on a number of pathogens.

Contraindications

A common limitation for all types and types of drugs is the rare individual intolerance to any components in their composition. Other contraindications for which the use of Tsipromed is prohibited or requires medical supervision include:

• pregnancy at any stage;
• period of breastfeeding (during instillations, the child is transferred to alternative nutrition and weaned);
• children's age from birth to 1 year;
• simultaneous therapy with the use of drugs with a pH value of 3–4 (pharmacologically incompatible).

It is also unacceptable to use medicine that has expired (after opening, the bottle is stored for a maximum of 30 days).

In complex therapy, a break of at least 5-10 minutes is maintained between instillations.

Moisturizing the sclera and protecting against fatigue - instructions for Hilokomod eye drops.

During pregnancy, the use of any medications is undesirable

Treatment methods for upper eyelid chalazion are described here.

Use in pediatrics

According to clinical studies, it is not recommended to use this product in the eyes of children. Tsipromed eye drops are not safe for children. This is due to the fact that the drug belongs to the pharmacological group of fluoroquinolones. The latter have a negative impact on the formation of joints and bones.

The drug is not recommended for use in adolescents. The drug can be prescribed only if there is a threat to the child’s life, if there is no effect from other antimicrobial medications.

But recent studies have found that ciprofloxacin enters the bloodstream in lower concentrations than other compounds related to fluoroquinolones. In this regard, the drug can be prescribed for the treatment of diseases in children, but it must be used with extreme caution.

How to treat a drug overdose

When using the drug described externally, no overdose was observed. Accidental ingestion of Tsipromed eye drops can be hazardous to health, although there are no specific signs of poisoning. Typically, headaches, nausea with vomiting, diarrhea, and sometimes anxiety and fainting may occur. Assistance to the victim is standard: cleansing the stomach and providing a sufficient volume of fluid. It is also necessary to create an acidic reaction in the urine to prevent the appearance of salt crystals in it (so-called crystalluria).

Reviews of ear drops "Tsipromed"

This is a very effective remedy for the treatment of acute otitis in children and adults; it is better to combine it with antibacterial medications; it can be used after barotrauma, trauma and perforation of the eardrum. It has an affordable price and good quality.

Patients say that ENT doctors prescribe various ear drops in clinics, but the only remedy that saves when persistent otitis occurs is Tsipromed. It is used both as eye and ear drops.

The drug is effective and good, it contains an antibiotic, it is enough to instill it for two days, and the otitis media will go away. In addition, patients do not experience side effects during treatment, for which they are grateful to the manufacturer.

Users also note the importance of pre-warming the bottle of product in hand and the correct frequency and dosage. They remain satisfied with the effect of the medicine, as a result, after 5-6 days the pain and ear congestion disappear.

The drug helps children. Thus, with ear congestion against the background of a purulent runny nose, several days of instilling Tsipromed helped get rid of the pathology. Parents recommend the medicine as affordable and effective.

Thus, reviews of ear drops are mostly positive. Users note the speed of action of the drug even when treatment with other medications did not bring the expected result. Patients consider the disadvantages of the drug to be side effects in the form of itching and irritation in the ear canal, and in some cases dizziness is possible.

Ciprofloxacin or Ciprolet – which medicine to choose?

In case of infectious diseases, it becomes urgent to search for an effective antibacterial agent that will be affordable. Among the drugs suitable for external and internal use, it is worth noting Ciprofloxacin and Tsiprolet.

Instructions for use of Ciprofloxacin

Operating principle

Ciprofloxacin actively fights against a large number of different pathogens. It produces a double effect - it disrupts the synthesis of proteins in bacterial cells and prevents their reproduction. Effective against the following pathogens:

• Staphylococcus (including aureus)
• Enterobacteriaceae
• Klebsiella
• E. coli of various strains
• Listeria
• Chlamydia
• Protea
• Beta-hemolytic streptococcus.

The substance has low toxicity relative to body tissues and is quickly distributed into them. Its concentration in individual organs is much higher than in the blood serum. Resistance to the active substance is developed slowly in bacteria due to the lack of enzymes.

Release form

The drug is available in several varieties:

• Tablets of 250 and 500 mg, coated, packaged in blisters
• Solution for intravenous administration 0.2% in 100 ml bottles
• Eye and ear drops 0.3% in a dropper bottle of 5 ml

Indications

The medication is designed to effectively treat many infectious diseases:

• Pneumonia, bronchiectasis, pleurisy, lung abscess, pulmonary cystic fibrosis
• Salmonellosis, cholera, typhoid, dysentery
• Cholecystitis, epimyema (suppuration) of the gallbladder, intraperitoneal abscesses
• Peritonitis and sepsis
• Adnexitis, salpingitis, endometritis, prostatitis
• Gonorrhea and chlamydia
• Osteomyelitis and septic arthritis.

It is also prescribed for the prevention of purulent and inflammatory complications after abdominal operations.

In ophthalmological and ENT practice, this medicine is prescribed for:

• Conjunctivitis, blepharitis, keratitis (except viral), corneal ulcer
• Eyeball injuries
• Otitis externa.

Contraindications

The use of the drug orally and intravenously is contraindicated during pregnancy and lactation, liver and kidney failure, previous strokes, mental disorders, epilepsy and convulsive syndromes.

Dosages and method of administration

For most internal infectious diseases, 250-500 mg is prescribed per dose, 2 times a day. In case of complicated pneumonia and severe course of the process, the single dose is increased to 750 mg. The interval between doses is 12 hours.

For intravenous drip administration, the single dose is 200 mg (100 ml), the number of injections is twice a day. For acute gonorrhea, prostatitis and cystitis without complications, the dose can be reduced to 100 mg (50 ml) per 1 administration.

If kidney function is impaired, the dosage is reduced by half. For elderly people, reduce the dose of the drug by 25-30%.

Eye and ear drops are used according to schemes corresponding to the diagnosis. For ophthalmological pathologies, instill 1-2 drops into the conjunctival sac of the affected eye every 4 hours, for a corneal ulcer - every hour.

Side effects

Taking the drug can cause certain ailments caused by the individual characteristics of the body:

• Tachycardia, arrhythmia, hypotension
• Nausea, vomiting, abdominal bloating, jaundice, liver necrosis
• The appearance of salt crystals, red blood cells, protein elements in the urine, glomerulonephritis
• Skin itching, photosensitivity, anaphylactic shock
• Pain in joints and ligaments, inflammation of tendons

Some side effects may be perceived as symptoms of an underlying disease, such as fatigue, headache and leukocytosis in the blood.

Storage

The tablets must be stored in cardboard containers away from light, maintaining a temperature of 15 to 25°C. The solution for infusion, eye and ear drops are stored in closed cabinets or a refrigerator at a temperature of 2 to 25 ° C. Shelf life is 2-3 years depending on the manufacturer.

special instructions

Tsipromed eye drops are a medication that can only be used after carefully studying the label. The instructions indicate several features of the use of the drug that cannot be ignored:

• It is not recommended to put medicine in your eyes while wearing soft contact lenses. This is due to the fact that the auxiliary components of the product have a damaging effect on the product.
• Hard contact lenses should be removed 15 minutes before instillation. They can also be installed back only a quarter of an hour after the procedure.
• Often, in order to stop the infectious process, doctors prescribe several drugs at once. In such cases, it is necessary to maintain an interval between instillations. It should be 5 minutes or more.
• When driving a vehicle or working with potentially dangerous equipment, it is important to consider that immediately after instillation, a decrease in visual acuity may occur. It is recommended to stop in advance or take a break from work for 15 minutes. During this time, vision is usually restored.

Tsipromed drops are prescribed exclusively by a doctor. Self-medication in the presence of infectious eye pathologies is unacceptable. In this regard, you can purchase the drug in pharmacies only with a prescription from a doctor.

The shelf life of the product is 2 years. If the bottle is opened, the drug must be used within 2 months. It is necessary to store the drops only in the original packaging in a dry and dark place, the temperature in which does not exceed 25 degrees. Freezing liquids is unacceptable.

If the patient wears soft contact lenses, then he should not use Tsipromed, because the preservative may be deposited in soft contact lenses and have adverse effects on ocular tissue.

You should remove hard contact lenses before instilling the drug and put them back on only after 15 minutes.

When using other ophthalmic drugs, the interval between their administration should be at least 5 minutes.

Immediately after instillation of the drug, vision clarity and mental reactions may decrease, which may reduce the ability to actively participate in street traffic, operate machines, or perform work without support. This occurs to an even greater extent when the drug is used simultaneously with alcohol.

How to properly instill the drug into a child's eye

In order for the results of treatment with the proposed remedy to be more noticeable, parents are obliged to follow the dosage and frequency of instillation suggested by the doctor. The treatment process should look like this:

• re-read the instructions for using the drops;
• wash your hands thoroughly;
• warn the child that the droplets will “pinch” a little;
• wipe the baby's eyes with a cotton swab;
• shake the bottle with drops;
• lay the child on his back so that his head is slightly thrown back (have someone hold him in one position);
• gently pull back the baby’s lower eyelid;
• squeeze a drop of medicine onto it without touching the eye;
• release the eyelid and let the child blink so that the product is evenly distributed;
• Wipe off any remaining drops with a clean napkin.

General characteristics

Both drugs contain ciprofloxacin as an active ingredient, to which the following microorganisms are sensitive:

• Escherichia coli.
• Salmonella.
• Shigella.
• Citrobacter.
• Klebsiella.
• Enterobacteriaceae.
• Proteas.
• Morganella morgani.
• Serrations.
• Hafnia.
• Edwardsiella tarda.
• Providence.
• Vibrios.
• Yersinia.
• Haemophilus influenzae and Pseudomonas aeruginosa.
• Moraxella.
• Aeromonas.
• Neisseria.
• Pasteurella.
• Plesiomonas.
• Campylobacter jeuni.
• Legionella.
• Brucella.
• Listeria monocytogenes.
• Mycobacteria, including tuberculosis.
• Staphylococci.
• Streptococci.
• Corynebacterium diphtheria.

In addition, there are the following similarities between the drugs Tsiprolet and Tsipromed:

1. Both drugs are manufactured in India .
2. Both drugs can be purchased with a doctor's prescription .
3. Both medications should not be prescribed to pregnant women or those who are breastfeeding.
4. During treatment with these drugs, you must be careful when driving a car and when working in potentially hazardous work.
5. Both drugs can cause allergies .
6. Tsiprolet and Tsipromed eye drops can cause burning, itching, pain, redness of the eye mucosa, swelling of the eyelids, photophobia, lacrimation, sensation of a foreign object in the eyes, unpleasant taste in the mouth immediately after instillation, blurred vision, keratitis, keratopathy, spots. or infiltration of the cornea, superinfection. In patients with corneal ulcers, a white crystalline precipitate may appear.

pharmachologic effect

An antimicrobial drug from the fluoroquinolone group.

Has a bactericidal effect. The mechanism of action is due to inhibition of the bacterial DNA gyrase enzyme, as a result of which DNA replication and the synthesis of bacterial cellular proteins are disrupted. Tsipromed acts on both reproducing and dormant bacteria. Tsipromed is active against gram-negative bacteria:

Escherichia coli, Salmonella spp., Proteus spp.
(indole-positive and indole-negative strains), Morganella morganii, Citrobacter spp., Klebsiella spp., Enterobacter spp., Yersinia spp., Vibrio spp., Campylobacter spp., Hafnia spp., Providencia stuartii, Haemophilus influenzae, Pasteurella multocida , Pseudomonas spp., Gardnerella spp., Legionella pneumophila, Neisseria spp., Moraxella catarrhalis, Acinetobacter spp., Brucella spp., Chlamydia spp.; gram-positive bacteria:
Staphylococcus spp., Streptococcus pyogenes, Streptococcus agalactiae, Corynebacterium diphtheriae, Listeria monocitogenes.

Differences

Tsiprolet and Tsipromed have the following differences:

Patient use of tablets

Tsipromed tablets with the active substance ciprofloxacin are an antimicrobial agent, a quinolone derivative. Acts against entero- and gram-negative bacteria, intracellular pathogens.

The tablets are taken orally, rapid absorption of the drug (absorption) and good distribution in tissues are noted.

Indications for the use of Tsipromed tablets are the diagnosis of infectious diseases of the lower respiratory tract:

• pneumonia and bronchitis;
• diseases of the ENT organs.

The drug is also prescribed for:

• cystitis and pyelonephritis;
• gonorrhea and prostatitis;
• skin infections, septic arthritis, osteomyelitis.

Tsipromed has been well recommended when used for prophylaxis after operations.

The tablets have side effects that can include nausea, vomiting, flatulence, and from the nervous system - headaches, insomnia, depression and nightmares.

The ciprofloxacin contained in Tsipromed tablets is contraindicated in children, pregnant and breastfeeding women.

Tsipromed is a potent antibiotic.

Mechanism of action

According to the instructions of Tsipromed, this antimicrobial drug belongs to a group of antibiotics characterized by antibacterial properties. Due to its unique composition, the drug stimulates the death of bacteria, which is achieved by suppressing the catalytic activity of DNA gyrase enzymes in bacterial cells.

As a result of this work of the drug, a disruption of the processes of DNA replication/doubling is observed with the subsequent death of pathogenic microorganisms. The bactericidal effect of treatment with Tsipromed drops is manifested both in relation to dividing bacterial cells and microorganisms that are at rest.

The medicine Tsipromed has a wide range of effects on pathogenic microorganisms, which is due to its antibacterial activity. The drug stimulates the death of a large number of species of gram-positive bacteria - staphylococci, streptococci, and gram-negative bacteria - Escherichia coli, gonococci, Klebsiella, Eirsinia, Shigella, Salmonella, Proteus, Pseudomonas aeruginosa.

In addition, due to their composition, the drops have an effect on specific pathogens, which are intracellular parasites:

• microbacteria tuberculosis;
• chlamydia;
• mycoplasma;
• legionella.

“After contact with the mucous membranes, be it the ear or the eyeball, Tsipromed drops are distributed throughout the affected tissues and have a pronounced therapeutic effect”

Evgeniy Smirnov, otolaryngologist of the highest category

Synonyms of nosological groups

DETAILS: Medifox - instructions for use, indications, analogues

Analogues of the drug Tsipromed

Despite the fact that Tsipromed is not that expensive, many patients still try to find cheap substitutes for this medicine.

Important! The selection of an analogue of a medicine prescribed by a doctor should be carried out exclusively by the same specialist. The specificity of the drug effect may be different. In addition, it is necessary to take into account all the nuances of the use and effect of the substitute on the body.

Analogues of Tsipromed in composition and mechanism of action on pathogenic microflora:

• Ciprofloxacin;
• Rotsep;
• Tsiprolet.

Among cheaper analogues:

• Tsifran;
• Basijen;
• Liproquin;
• Recepro;
• Sofradex;
• Phloxamed;
• Cifroxol.