Neo-Penotran and alcoholic beverages. Is it possible to take alcohol and Neo-Penotran

The variety of suppositories for treating various types of inflammation in the vagina sometimes confuses even experienced doctors. The most popular of them are combination products that contain two or more components. This way, with minimal examination, you can prescribe effective treatment. NEO-PENOTRAN suppositories are one of the popular and effective drugs for the treatment of vaginitis of various natures. How and when to use candles correctly? Is it effective to take NEO-PENOTRAN during menstruation?

Read in this article

To whom and when is it prescribed?

The range of indications for prescribing suppositories is very wide. This is due to the composition of the drug and its basic properties. There are two forms - regular and extended-release (Forte). The difference is in the amount of active components. You can also find the form of suppositories and vaginal tablets, which has no fundamental difference.

The main active ingredient is metronidazole. Miconazole, an antifungal drug, has also been added. Metronidazole has a detrimental effect on protozoa (amoeba, trichomonas), pathogenic microorganisms in the vagina (gardnerella, streptococcus and others). Moreover, the drug destroys all pathogenic flora, and does not simply inhibit its reproduction. Miconazole is one of the effective fungicidal drugs. Can be used to treat both chronic and acute fungal infections. Remarkably, it even slows down the formation of new pathogenic bacteria.

Thus, the spectrum for prescribing candles:

candidal colpitis (thrush),
bacterial vaginosis,
trichomonas colpitis,
nonspecific mixed infection in the vagina,
recovery after cauterization of the cervix,
sanitation on the eve of surgical interventions (curettage, abortion, abdominal surgery, etc.),
in the complex treatment of cervical dysplasia.

The medicine can be used both during exacerbation of infections and for the treatment of chronic lesions.

The drug can be used in girls over 16 years of age who are sexually active. During pregnancy, the use of NEO-PENOTRAN is prohibited up to the 15th week inclusive, as its components can have a negative effect on the fetus.

https://youtu.be/RL2yh742J-c

Contraindications

NEO-PENOTRAN is absorbed from the vaginal mucosa into the systemic circulation. The drug is metabolized in the liver. This determines some restrictions in its use. These include:

Allergic reactions to any component of the drug individually or unsuccessful attempts to use NEO-PENOTRAN earlier.
Women with chronic liver pathology should take it with caution, especially when taking several medications simultaneously, which increases the load on the organ.
The drug should not be used during breastfeeding and in the first trimester of pregnancy due to possible exposure to the baby. If it is absolutely necessary to use the drug during lactation, human milk should be excluded from the child’s diet for the entire duration of use and for two more days after completion of the course.
If the use of NEO-PENOTRAN and a missed period suddenly coincide, you should immediately take a pregnancy test. If the latter is confirmed, you should stop taking it and consult a doctor.
NEO-PENOTRAN should not be used by women suffering from epilepsy, as well as those who have ever had even single convulsive seizures.
With long-term use, metronidazole can affect blood composition. Therefore, if pathology is present, use should be postponed until recovery or replaced with another drug.
It is not recommended to use NEO-PENOTRAN in children under 16 years of age.

Side effects and combination with alcohol

As mentioned earlier, most often Penotran is well tolerated; numerous trials of the drug have shown that it causes almost no adverse reactions. Sometimes there may be irritation in the vaginal area. If you notice such a symptom in yourself, and it lasts more than three days, you need to interrupt the course of therapy and consult a doctor so that he can change the drug to one that is suitable for you.

The drug may cause some side effects, especially when combined with alcohol:

Bad mood;
prolonged diarrhea;
rash all over the body;
constipation;
pain in the genital area;
vomit;
muscle weakness;
headache;
excessive fatigue;
dry mouth.

All these side effects are inherent in this medicine, but most often they do not occur at all, patient reviews have confirmed this. I would like to note that pregnant women cannot use Neo Forte suppositories in the first trimester. After this period of time, they can be used as usual for the rest of the pregnancy.

Important information! People with severe diseases of the central nervous system and liver should not take Penotran. It is recommended not to have sexual intercourse until the end of the entire course of therapy, since the likelihood of infecting your sexual partner is very high. He also needs to undergo treatment with the drug only orally. I would like to note that you can drink alcohol during the period of using Penotran three days after taking the medication.

Neo Forte suppositories should not be used for therapy in virgins and very young girls. Neo Forte candles can be used by women when driving; they are absolutely not dangerous. Penotran is not recommended to be taken simultaneously with other medications, as it can greatly distort the reaction of another medication or make it completely ineffective. The product should be stored in a dark place, away from children.

When this drug is used simultaneously with alcohol, a so-called disulfiram reaction may occur. With the simultaneous use of metronidazole, certain disturbances in the central nervous system may occur. Also, this medication, together with alcohol, can increase the toxicity of lithium. With a single dose of alcohol and metronidazole, the level of phenytoin in the blood itself decreases.

You can still talk about this topic for a very long time, but patient reviews have long proven that alcohol and medicine cannot be taken at the same time, and this applies not only to this drug. Any medicine can cause a lot of side effects when combined with alcohol. You need to know this and follow the rules.

Admission course

There are two forms of release of the drug. Regular NEO-PENOTRAN contains 100 mg of miconazole and 500 mg of metronidazole. This is the most commonly used option. NEO-PENOTRAN Forte contains 200 mg of miconazole and 750 mg of metronidazole. It is used more often for trichomonas colpitis or concomitant infection.

But there are standard prescribing methods. They look like this:

For uncomplicated infection or preventive sanitation, it is possible to prescribe suppositories one at night for 7 or 14 days.
In more complex cases, apply one capsule twice a day for a week.

Each suppository is placed deep into the vagina. It is better to do this in a lying position. After administration, you should remain in a horizontal position for 15-20 minutes to prevent the dissolved drug from leaking out of the vagina. For ease of intravaginal use, the kit includes a special finger attachment along with the drug, which can be used if necessary.

Treatment with NEO-PENOTRAN suppositories is often combined with oral administration of antibacterial or other drugs. This enhances the action and effect of the medicine.

Women often worry whether it is possible to insert NEO-PENOTRAN suppositories during menstruation, if the course of treatment fell on these days. If necessary, you can add medicine only on days of minor discharge. If you have heavy menstruation, you should take a break for several days while continuing to take the pills (if they were prescribed).

Side effect

Metronidazole and miconazole for intravaginal use are well tolerated, rarely causing adverse reactions. These include:

various types of allergic manifestations (rash, itching, swelling both in the vagina and genitals, and on any part of the skin);
headaches, even migraine-like, cramps - only with prolonged use;
nausea, changes in taste preferences, sometimes diarrhea or constipation;
unpleasant sensations (itching, burning) in the vagina after using the drug.

It is important to know

During treatment of any sexually transmitted infection using vaginal products, you should abstain from sexual intercourse. Firstly, reinfection is possible if the partner does not undergo treatment. Secondly, NEO-PENOTRAN can affect the properties of latex, which can contribute to the rupture of the condom during sexual intercourse.

For those who have liver pathology or diseases of the nervous system (including functional ones), the drug can be used only after prior consultation with a doctor and only as prescribed.

Suppositories (or even vaginal tablets) should not be used orally. If this happens, you should rinse the stomach as soon as possible or induce vomiting. Otherwise, adverse reactions and signs of drug overdose may occur.

We recommend reading the article about restoring microflora after thrush. From it you will learn about vaginal dysbiosis after candidiasis, and medications that allow you to restore a normal environment.

Can I take it during menstruation?

When starting a course of treatment, it is advisable to start taking the drug one and a half to two weeks before menstruation. NEO-PENOTRAN suppositories during menstruation may not have the desired therapeutic effect.

If necessary, you can put the medicine on days of minor discharge. But in no case should you take vaginal tablets or then use several at once to “catch up” with the treatment. As a rule, complex therapy is prescribed for sexually transmitted infections. Therefore, during critical days, it is necessary to stop taking oral medications, and then refill the missed suppositories according to the scheme.

NEO-PENOTRAN is a universal and effective suppository for the treatment of a wide range of sexually transmitted infections. The regimen and indications for prescription should be determined by the doctor. Independent uncontrolled use can lead to adverse reactions and complications, and an acute infection can become chronic. Whether NEO-PENOTRAN can be taken during menstruation or other bleeding (for example, after cauterization of the cervix), as well as other features of administration in a particular situation, can only be determined by a gynecologist.

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We recommend reading the article about neo-penotran suppositories during menstruation. From it you will learn about indications for use and contraindications.

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Contraindications and adverse reactions to taking Neo-Penotran

Suppositories must be inserted into the vagina; be sure to use the finger guards that are included in this drug. For candidiasis, as well as vulvovaginitis, it is necessary to administer Neo Forte suppositories twice a day, the course of treatment is two full weeks. If the disease returns after a while, you must take the course again and administer Neo Forte suppositories twice a day for fourteen days.

During the treatment of trichomoniasis, it is necessary to combine treatment; in addition to the use of suppositories, metronidazole should be taken orally. The dosage of the substance does not differ from the above. During therapy, you must completely abstain from sex, this is very important! It should be noted that even older women can use Neo Forte suppositories; the main thing is to first consult a doctor to confirm this.

To date, there have not been any cases of overdose with this drug.

But, like any medicine, Penotran has its own symptoms of overdose, which must be voiced:

Vomiting.
Poor coordination.
Inflammation of the mouth.
Cramps.
Diarrhea.
Nausea.
Itching of the skin.
Dark urine.

But you shouldn’t be afraid of all of the above, since such symptoms appear extremely rarely. Feedback from patients using this product confirmed that Neo Forte suppositories do not pose any danger to human health.

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Contraindications to the use of this medication are:

first trimester of pregnancy;
breast-feeding;
individual intolerance to the components included in the drug;
childhood;
epileptic and convulsive seizures;
severe liver dysfunction;
disorders of the central nervous system;
disturbances in plasma production.

During pregnancy, the drug should be prescribed with caution and preferably only when the expected benefit to the mother potentially outweighs the risk of developing fetal pathologies. The use of the drug while breastfeeding is prohibited; it can be restored no earlier than two days after taking the last dose of the medicine.

It is not recommended to use this medication during the menstrual cycle, since all active ingredients will be excreted along with the discharge, which will not bring any therapeutic effect. Therefore, during this time, treatment with this drug is interrupted and restored again after the end of the cycle.

Sexual contact is also prohibited while undergoing treatment with Neo-Penotran. Even with the use of a condom, since the drug helps reduce the strength of latex products.

Often, when using this medicine to treat cervical erosion, a white discharge may appear. But the presence of red bloody impurities in them is a reason to immediately contact a gynecologist, who, after passing the examination, will prescribe adequate treatment.

When using the drug, local and systemic side effects may occur. Most often, patients experience local reactions, which are expressed in:

hyperemia of the perineum and vaginal mucosa;
burning and itching;
irritation and redness of the epidermis.

Typically, such reactions occur at the very beginning of using the drug and, as a rule, pass quite quickly. However, if adverse reactions persist or are severe, you should stop taking the drug and consult a doctor.

Systemic side effects most often develop against the background of low absorption of this drug. Their appearance is quite rare. They can manifest themselves in:

increased irritability;
headache and dizziness;
ataxia;
nausea, vomiting, stool disorders;
violation of taste sensations;
increased activity of liver enzymes;
leukopenia;
convulsive syndrome.

The combined action drug Neo-Penotran (as well as Neo-Penotran Forte), produced in the form of suppositories, is intended for vaginal (by insertion into the vagina) use of a drug that is effective against a wide range of pathogens of infections of the female reproductive system.

Neo-Penotran is a combined drug with antibacterial and antifungal action

Calling it an antibiotic is not very correct - in addition to the substance that affects microbes (the antibiotic itself), it also contains substances that are active against fungi (fungicide) and protozoa (antiprotozoal drug).

The sum of active ingredients allows you to treat diseases caused by combined microflora (microbial-fungal-protozoal, or consisting of microorganisms of two categories). This property is very convenient for consumers and does not require separate dosing of each component.

Despite the ease of use, unauthorized treatment with the drug is not recommended for a number of reasons.

These include ignorance:

structure and properties of one’s own body;
type of infectious agent, its properties and capabilities;
capabilities and properties of the composition used;
the duration of the course of necessary treatment;
frequency of administration of the drug and its adequate dose.

The dose should be sufficiently effective against pathogens and at the same time safe for the body.

All the nuances of the treatment process are purely individual and must be assessed by a doctor, who will also select the most effective and timely combinations and doses (for one dose, for a day and for a course).

Composition of the drug

The universality of action on a wide range of pathogenic microorganisms is explained by the inclusion of two categories of substances in both modifications of the drug (regular and forte):

Metronidazole;
Miconazole.

Metronidazole is the structural formula of the main active ingredient of the drug Neo-Penotran

The first ingredient (antiprotozoal action) actively suppresses various types of protozoa, the second (fungicide) – pathogenic fungi, and the overall result of their effect is also the destruction of bacteria harmful to the human body.

The drug is effective not only against trichomonas, but also against pathogens classified as other categories of living beings:

aspergillus;
fungi of the genus Candida;
cryptococci;
streptococci;
gardnerell.

Due to the combination of ingredients active against various classes of pathogens, a drug is prescribed to suppress microflora, the reproduction of which leads to the occurrence of:

candidiasis;
trichominiasis;
vaginitis (colpitis) of a bacterial nature;
vaginal infections of fungal origin;
infections caused by mixed microflora.

The compatibility of Neo-Penotran and alcohol when used simultaneously depends on the patient’s level of health at the start of treatment. The presence of chronic diseases can change the course of biochemical reactions in the body to critical levels, as well as regular consumption of alcoholic beverages.

Doctors recommend refraining from drinking alcohol while taking Neo-Penotran

A change in the acid-base balance of the blood to the acidic side (and such a combination as Neo-Penotran and alcohol acidifies the blood) leads to a distortion of the action of the drug, which in other conditions gives an excellent result.

If you use Neo-Penotran suppositories and drink alcohol afterwards, the body’s reaction may be different. If there is significant previous provocation of the liver or kidneys, the medication can, having accumulated in the body, cause the appearance in the blood of chemical compounds intolerable to it.

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It is not stated in the instructions, but judging by numerous reviews, after treatment with Neopenotran, uncharacteristic bloody or pink discharge often appears.

There can be many reasons, so if such a symptom occurs, you should immediately consult your doctor. The examination will show what causes this reaction in the body.

The individual reaction of the body to the main or auxiliary components - this may be ordinary intolerance to the active substances (metronidazole or miconazole) or even an allergy.

In this case, white or yellow (sometimes bright yellow) copious discharge is observed, which is sometimes accompanied by other uncomfortable sensations (itching, burning, inflammation, rash, etc.).

In such a situation, you need to consult with a gynecologist who will prescribe you an alternative medicine.

Antibacterial suppositories Neo-Penotran and Neo-Penotran forte, when taken, for example, with oral contraceptives, can lead to some disruptions in the body, not to mention the fact that they completely reduce the contraceptive effect. Therefore, you need to promptly inform your gynecologist about taking any medications, so that the drug is selected taking into account the possibility of their unhindered interaction.

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Diseases

Concomitant diseases – pathologies of the cervix (erosion, tumor) and other gynecological diseases. If they were noticed by a doctor in time, then he should warn you about the possibility of such a side effect. It is not necessary to change the drug if it does not cause other negative symptoms.

For example, after a biopsy of the eroded cervix, a small wound remains on it, which, due to the superficial location of the vessels, can bleed for some time, thereby causing brownish or bloody discharge. Follow the link to find out what discharge after a cervical biopsy may indicate a pathology, and what secretion is normal.

If, after a few days of regular administration of suppositories, a cheesy white discharge is observed, then the treatment is unsuccessful and the thrush is still progressing.

Perhaps the reason is non-compliance with instructions or neglect of the rules of personal hygiene and nutrition during therapy.

Each of the described cases must be confirmed by a specialist. Further decisions on continuing treatment with Neo-Penotran suppositories (Penotran forte) or changing the drug are made by the gynecologist based on examination and tests.

Types of suppositories and dosage of the drug

Three types of the drug are available in composition - Neo-Penotran, Neo-Penotran Forte and Neo-Penotran Forte L. The main active ingredients in suppositories are metronidazole and miconazole. The difference between drugs lies in the dose, as well as in additional ingredients. Therefore, each drug has its own characteristics of use - schemes, doses, duration.

Compound	Neo-Penotran	Neo-Penotran Forte	Neo-Penotran Forte L
Miconazole	100 mg	200 mg	200 mg
Metronidazole	500 mg	750 mg	750 mg
Lidocaine	No	No	100 mg

When are suppositories prescribed?

Neo-Penotran suppositories are used to treat vaginal infections caused by one pathogen or several at the same time. The active ingredients have a therapeutic effect not only at the level of the vaginal mucosa, but also penetrate into the bloodstream, thus enhancing their effect.

Metronidazole in the suppositories has a detrimental effect on Trichomonas, Gardnerella, peptococci and peptostreptococci. Miconazole is an antifungal substance; it suppresses the formation of ergosterol, this is the main component of the wall of fungi, which leads to their death. The fungicidal effect applies to candida, which causes thrush.

Thus, Neo-Penotran has anti-inflammatory, antiprotozoal and antifungal effects. Indications for its use are the following conditions:

treatment and prevention of thrush, for example, when taking antibiotics or when immunity is reduced after serious illness;
trichomonas colpitis;
bacterial vaginosis;
for the prevention of complications after surgical treatment of the cervix (cauterization, conization, etc.);
in the complex of treatment of erosions, dysplasias;
on the eve of childbirth or cesarean section;
for the treatment of chronic cervicitis, endometritis, adnexitis.

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And here is more information about the signs and treatment of nonspecific colpitis.

Pharmacological effect

When ingested, the components of neo penotran suppress the vital activity of pathogenic microflora that are sensitive to them. The combination of two active substances avoids relapses of infection, which are often observed with monotherapy.

Metronidazole prevents the production of nucleic acids that make up the DNA of microbes, which causes their death. Metronidazole is effective against most pathogens of vaginal infections. Due to the fact that metronidazole enters the bloodstream, its amount in the body is the same throughout the entire treatment period.

Miconazole is a strong antifungal agent that destroys the cell membranes of fungi. Miconazole destroys most fungal infections, and is especially effective against candida, aspergillus, and cryptococcus. The drug also prevents the development of some gram-positive microbes.

When these components are used intravaginally, a certain amount of metronidazole is detected in the blood, miconazole does not enter the blood. The first is processed by the liver and evacuated from the body over 6 to 10 hours in the urine.

Neo-Penotran during menstruation: can it be used and how?

It is not advisable to take Neo-Penotran during menstruation; it is optimal to adjust treatment to the menstrual cycle. If the critical days “hit” the time of laying suppositories, you should stop taking them on the days of maximum discharge. If it is spotting, you can continue treatment.

Using Neo-Penotran during menstruation is fraught with a decrease in the therapeutic effect of the drug due to the fact that some of the components will simply be released with copious discharge.

This may lead to the development of pathogen resistance to the drug due to an artificial reduction in dosage.

As a rule, treatment with Neo-Penotran is carried out in combination with other oral medications. Therefore, during your period you should take oral tablets, and leave all vaginal forms for later. Under no circumstances should you take Neo-Penotran orally or “catch up” with treatment by placing suppositories more often after a break or several at once. This may lead to side effects.

Contraindications for use

Neo-Penotran has a number of contraindications. This is due, among other things, to the fact that the drug penetrates the systemic bloodstream and undergoes metabolism in the liver. You should not be treated with the drug in the following situations:

if there is hypersensitivity to any component of the drug;
for liver pathologies - only as prescribed by a doctor;
for diseases of the blood and bone marrow, since metronidazole in the suppositories can affect the process of hematopoiesis;
for neurological diseases - seizures, epilepsy;
children under 16 years of age.

It is not recommended to use the product in the first trimester of pregnancy, as well as during lactation. There is no evidence of serious harm from the drug, but safety has not been studied, so use is only possible in cases of extreme necessity.

Do suppositories have contraindications and side effects?

Neo Penotran Forte is an antibiotic and, naturally, it has contraindications, in the presence of which it cannot be used, as this can lead to various complications.
Contraindications for this drug include the following conditions:

Individual intolerance to the components included in its composition.
Liver diseases.
First trimester of pregnancy.
Lactation.
Cramps.
Epilepsy.
Alcoholism.
Serious psychological disorders.
Blood diseases.
Children under 16 years old.

It should be noted that this drug also has limitations during its use. When using vaginal suppositories, it is strictly forbidden to drink alcohol or have sexual intercourse.

As for the use of suppositories during menstruation, the opinions of experts are divided. Some argue that this medicine cannot be used during menstruation, since all the active components of Neo Penotran will come out along with bloody discharge without having time to exert their effect. Others say that the course of treatment should not be interrupted, as this will lead to a decrease in the effectiveness of the therapy.

Also, the use of these suppositories may be accompanied by side effects:

Migraine.
Allergic rash like urticaria.
Dry mouth.
Frequent mood changes.
Abnormal stool.
Attacks of nausea and vomiting.
Cramps.
Irritation of the vaginal mucous membranes, which causes itching and yellow discharge after Neo Penotran.

Women may also experience strong white discharge after Neo Penotran. Their occurrence is due to the fact that after inserting a candle into the vagina, it begins to melt and flow out. But this phenomenon is observed no more than 30-40 minutes.

The effect of anticoagulants increases,
The damaging effect of lithium drugs increases,
Concomitant use with phenobarbital reduces the amount of metronidazole in the blood,
The components of neo penotran inhibit the activity of some cardiac drugs (cisapride, etc.), so arrhythmia may occur,
Cimetidine increases the amount of metronidazole in the blood,
The components of the drug affect the level of procainamide and theophylline in the blood.

The drug is stored at room temperature for three years from the date of release. Sold in pharmacies with a prescription.

Treatment regimens

The treatment regimen must be prescribed by a doctor. Depending on the clinical situation, drugs with different dosages of active ingredients are used. The following standard recommendations generally apply:

it is necessary to place one Neo-Penotran suppository deep into the vagina, preferably at night for a week or two;
if necessary, double the dose - one suppository twice a day.

After placing the suppository, you need to lie down for about 10-15 minutes, otherwise the suppository may go down into the lower third of the vagina and leak out after dissolving. For convenience, you can use a special nozzle to insert the suppository into the vagina.

Characteristics of the drug

Cleanliness and sex with a regular partner cannot always protect the female body from vaginal infections. Sometimes just going to the pool is enough to catch a serious sore. Already the first symptoms of the disease (itching, frequent urination, pain) create internal discomfort and reduce the quality of life. If the disease is neglected, complications appear that lead to serious health problems. Therefore, treatment should be started as soon as possible.

One of the drugs that copes well with vaginal infections is Neo-Penotran. It helps well in treating advanced cases of inflammation of the vaginal mucosa, vaginal infections, thrush and other fungal infections. The candles owe their effectiveness to a successful combination:

micronized metronidazole – antimicrobial and antiprotozoal (destroys protozoan microorganisms) drug;
micronized miconazole nitrate, an imidazole derivative, the action of which is aimed at combating fungal infections and certain types of gram-positive microorganisms;
lidocaine – analgesic effect.

The first drug is effective against most bacteria that cause vaginal infections, while the action of the second is directed against fungi of the Candida group, aspergillus, and cryptococcus. Suppositories are inserted into the vagina once a day, the course lasts a week. In case of relapse, repeated treatment is increased to two weeks.

https://youtu.be/_Gs0IqK4DDM

There is no clear opinion regarding the use of the drug during menstruation. Some doctors say that the course must be interrupted and continued after the end of menstruation, others say that treatment cannot be interrupted, and only use pads and tampons are prohibited. It is best to discuss this controversial issue with your doctor, but keep in mind that most of the drug may come out along with the discharge.

Under no circumstances should you self-prescribe the drug or increase the dosage or course of treatment at your own discretion. This can lead to various side effects in the body.

Possible complications from taking

The use of Neo-Penotran may be complicated by the following conditions:

allergic reactions - rashes, itching, swelling of the tissues of the genital organs and perineum;
with prolonged use and exceeding doses - convulsions and migraines;
dyspeptic disorders - nausea, diarrhea, constipation, metallic taste in the mouth, abdominal pain, heartburn.

In an overdose, nausea to vomiting, convulsions, and dizziness are noted. The appearance of bloody discharge from the vagina when taking the medicine is not considered normal; this should be reported to the doctor.

Side effects

Usually, taking Neo-Penotran is not accompanied by side effects. They are possible when taking the medicine if there are contraindications or non-compliance with instructions (for example, exceeding the norm). The side effects of Neo-Penotran include the following manifestations:

Irritation of the vaginal mucosa, resulting in itching, yellow or bloody smears.
Hives (rash).
Migraine.
Change of mood.
Problems with coordination.
The appearance of seizures.
Pain in the epigastric region.
Dry mouth.
Constipation or diarrhea.
Vomiting, nausea.
Reduction of leukocytes in the general blood test.

An unexpected reaction may occur when Neo-Penotran is combined with certain medications. For example, simultaneous use of a drug with anticoagulants increases the strength of their action; when using drugs with lithium, their side effects increase. Neo-Penotran can reduce the effect of some medications aimed at treating the cardiovascular system, which can lead to arrhythmia. Therefore, you must inform your doctor about the use of any medications.

Changes in menstruation after Neo-Penotran suppositories

The suppositories themselves do not affect the menstrual cycle and discharge during menstrual periods. This is a complex anti-inflammatory drug. However, after treatment, normalization of the cycle, a decrease in the amount of discharge, and the disappearance of an unpleasant odor (if any) may be observed. This is due to the fact that by getting rid of the infection, the function of the genital organs is restored.

If suppositories are placed during menstruation, there may be a slight increase in discharge and the appearance of impurities of the dissolved drug in them.

Watch this video about the mechanism of action and indications for the drug Neo-Penotran:

Neo-Penotran analogues

Before purchasing an antibiotic or antifungal agent, consult a specialist. You can choose from the catalog, order and buy Neo-Penotran suppositories for thrush in the online store, but their action is not always reliable and effective. This is a consequence of superficial self-medication. In fact, some people are more suitable for Neo-Penotran analogues with identical pharmacological effects in the body. Doctors place special emphasis on the effectiveness of the following medications:

Klion-D 100;

Clomesol;

Clotrimazole;

Metromicon-Neo;

Ketonazole;

Livarol;

Clevazol;

Metrogyl Vaginal;

Mycogal;

Ginalgin;

Kandisan;

Gynofort (cream);

Candibene (cream);

Gravagin;

Econazole;

Trichopolum;

Pulsitex.

streptococci;

Restrictions during treatment with suppositories

You should use the medicine only as prescribed by a doctor, who will evaluate all the benefits and possible harm from the medicine. Neo-Penotran is prescribed with caution in the following situations:

in women with liver diseases;
while taking a large number of medications;
during pregnancy, especially in the first trimester, and during breastfeeding - the components of the drug, absorbed into the blood, enter breast milk;
if pregnancy is not excluded;
for epilepsy.

It should be borne in mind that the drug can interact with the latex of the condom, so you should refrain from sexual intercourse during the period of treatment.

And here is more information about the choice of candles after cauterization of erosion.

Neo-Penotran is a combination medicine, available in the form of suppositories. The drug should be used only as prescribed by a doctor, as it has a number of contraindications, and adverse reactions cannot be ruled out. Schemes and variations of the drug are also selected by a specialist based on the clinical situation.

Using vaginal suppositories for thrush is convenient and simple. It is impossible to figure out which of them are the best and most effective, which ones will help and can be used during pregnancy, and which pills need to be added on your own.

Almost always, suppositories for cervicitis are used in complex treatment. In gynecology, vaginal and rectal treatments can be used for acute and chronic cervicitis in women. Do they always help in treatment?

The multicomponent drug "Terzhinan" for cervical erosion is prescribed quite often, as it is highly effective. Just one candle at night - and the result will not be long in coming.

Due to bacteria or excessive attention to personal hygiene, nonspecific colpitis may develop. The reasons may also lie in unprotected sexual intercourse. Treatment includes medications and suppositories, which are also prescribed for chronic colpitis. How dangerous is he?

Use during pregnancy and lactation

Both tablets and suppositories are inserted into the vagina as deeply as possible. Suppositories are administered using the fingertips supplied with them. Before inserting the tablet, it should be slightly moistened.

For candidiasis, bacterial vaginosis, trichomonas vulvovaginitis, one suppository or tablet twice a day (morning and evening) for seven days. Or just at night, one at a time for fourteen days.
For recurrent forms of vaginitis or in case of insensitivity to other drugs, one suppository (tablet) twice a day for fourteen days.

For trichomoniasis, local treatment is usually combined with oral metronidazole. The dosage of the drug Forte does not differ from that described above. During the treatment period, you should refrain from copulation. The dosage does not change for elderly patients.

It is forbidden to use neo penotran in the first 15 weeks of pregnancy. Then, until childbirth, the drug can be used only as prescribed by a doctor. Since metronidazole passes into the blood and milk, the drug should not be used during breastfeeding or the baby should be switched to artificial feeding. You can breastfeed your baby a day or two after the last dose of neo penotran.

Release form

The drug Neo-Penotran for intravaginal use is available in the form of suppositories No. 7. The medicine is placed in a contour package of 7 suppositories each. Depending on the quantitative ratio of the active substances relative to each other, several variations of the medicinal product are presented on the pharmaceutical market:

"Neo-Penotran", the chemical composition of which contains 500 mg of metronidazole and 100 mg of miconazole nitrate.
"Neo-Penotran Forte" contains 750 mg of metronidazole and 200 mg of miconazole nitrate.
"Neo-Penotran Forte-L." The ratio of components in this suppository is identical to Penotran Forte. The only difference between the drugs is that Forte-L contains lidocaine in an amount of 100 mg.

Visually, vitepsol is a white, solid substance that is tasteless and odorless. A similar base for candles is made by pouring.

Chemical composition of the drug

Relying on the opinion of practicing gynecologists, we will call Neopenotran vaginal suppositories the most popular and effective remedy in the fight against infections affecting the organs of the female reproductive system. The release form includes both suppositories and tablets. To select the appropriate dosage form or adjust the course of therapy taking into account the onset of menstruation, you must consult with your doctor.

Metronidazole

Based on the information contained in the instructions for the drug and relying on articles by specialists in the field of gynecology, we can conclude that the main component of the drug is metronidazole. This substance has a strong antimicrobial effect and is prescribed both as part of medications and independently for parasitic infections of the body.

The chemical characteristics of the component states that metronidazole belongs to the nitro-5-imidazole family. Drugs in this group are designed specifically to combat protozoan microorganisms, which, when entering the human body, can provoke the emergence and development of infectious diseases. In most cases, metronidazole acts as an “ambulance” in the relief of the following infectious diseases:

Trichomoniasis;
Giardiasis;
Amoebiasis;
Stomach ulcers;
Anaerobic infections that affect various body systems.

One of the features of the effect of this component on a woman’s body is a change in urine pigmentation during the treatment period. The liquid takes on a dark, rich color. This phenomenon should not cause concern. This coloration of urine is a physiological reaction of the body to the effects of metronidazole.

Miconazole nitrate

Based on the annotation for the drug, it can be noted that the composition of the drug Neo-Penotran in the form of suppositories contains miconazole nitrate. This active component has a pronounced antimicrobial effect on the human body. The therapeutic effect is achieved by changing the lipid composition of the membrane of harmful fungal cells, provoking the development and maintenance of the “life activity” of the infection. Such an “invasion” leads to cell necrosis, and therefore the elimination of the entire infectious focus. The main microorganisms that can be eliminated using the substance are:

Dermophytes;
Yeast fungal forms;
Gram-positive microorganisms.

One of the main advantages that allows us to talk about drugs containing miconazole nitrate in their composition as the main ones in the fight against infections affecting the female genital tract is the ability to instantly relieve burning and itching that accompany most fungal diseases of the genital organs.

Witepsol

The basis of the Neo-Penotram vaginal suppository is Witepsol in a dosage of 1.9 grams. The chemical composition of this substance is a mixture of triglycerols and saturated fatty acid lauric acid. This suppository base is compatible with most medicinal components.

Is it possible to insert suppositories during menstruation? Neo-Penotran suppositories can be used, since according to experts, with intravaginal use of drugs based on metronidazole, menstruation is not a reason to stop or suspend the course of treatment.

An undoubted advantage of preparations based on miconazole nitrate is the absence of a negative effect on vaginal pH. Vaginal suppositories with this active ingredient do not dry out the natural flora.

Negative consequences when combining medication with alcoholic beverages

Neo-Pentoran is also well tolerated. A large number of tests conducted to identify the properties of the drug itself have demonstrated a complete absence of side effects. In some cases, minor irritation may occur, which usually spreads to the vaginal area.

If you drink alcohol during therapy, you may experience some side effects:

deterioration of emotional state (possible depression);
the appearance of diarrhea;
rash spreading over the entire body;
the appearance of constipation;
pain in the genitals;
the appearance of frequent gag reflexes;
some weakness in the muscle area;
increased fatigue;
the occurrence of dry mouth.

Is it possible to drink alcohol with cystitis (beer, wine, etc.)

Each of these side effects is caused by the medicine we are describing. In most cases, users do not have to deal with these negative manifestations. Female representatives who are pregnant in the first trimester should not take the drug. At the end of this time period, therapy can already be resumed and continued until the final stage of pregnancy.

It must be remembered that people who suffer from liver diseases, as well as the central nervous system, should not use this medication. Until the course of treatment comes to an end, it is not recommended to have an active sex life, because there is a high probability that the pathology will be transmitted to the partner.

We suggest you read: Are women allowed to drink alcohol after biorevitalization?

Virgins and young girls should not use the drug. Women should use candles while traveling by car. Neo-Pentoran cannot be used in parallel with other medications, because it can negatively affect the action of another drug, suppressing its effectiveness. The drug must be stored in a dark place.

If the drug is taken together with alcohol, a disulfiram-type reaction may occur. In this case, various disorders in the central nervous system may occur. The medication can increase the content of toxic lithium components if you also drink alcohol while taking it. Also, with this regimen, the content of phenytoin in the blood may decrease.

If there is a high concentration of the drug in the digestive tract, it is necessary to immediately rinse the walls of the stomach. In this case, it is necessary to consult a doctor only when the esophagus begins to contain about twelve grams of metronidazole. It is not possible to find a special remedy in this situation.

If the dose is exceeded, patients may experience the following symptoms:

nausea;
the appearance of a gag reflex;
abdominal pain;
the appearance of severe diarrhea;
itching on the skin;
presence of a metallic taste in the mouth;
the appearance of paresthesia;
the occurrence of symptoms of leukopenia;
urine has a dark unnatural color, the appearance of a dark shade.

Pharmacological properties

Thanks to the combination of antiparasitic and antimicrobial active ingredients, Neo Penotran vaginal suppositories are widely used in gynecology. Once in a woman’s body, the drug has an immediate effect, suppressing the reproduction and activity of pathogenic microorganisms. The combination of metronidazole and miconazole nitrate is harmful to the following types of microorganisms:

The drug is used to treat thrush during menstruation.

In modern gynecology, Neo-Penotran vaginal suppositories are prescribed by specialists for the treatment of the following diseases:

Anaerobic vaginosis;
Trichomonas vulvovaginitis;
Nonspecific vaginitis;
Gardnerella vaginitis;
Colpitis of a trichomodal or candidal nature;
Mixed type genital tract infections;
Dysplasia;
Infectious lesions resulting from cauterization of the cervix.

Some doctors recommend a course of vaginal suppositories as a prophylaxis after surgical operations affecting the organs of the woman’s reproductive system (cleaning, curettage, abortion).

Brief information about the drug

Neo-Penotran suppositories are used in gynecology for the treatment of vaginal diseases such as:

bacterial vaginosis;
thrush (vaginal candidiasis);
inflammation of the vaginal walls of an infectious nature;
mixed type infections caused by pathogenic microbes located on the mucous membrane of the female genital organs.

During the period of use, suppositories have an antibacterial, antifungal, antiprotozoal effect, which is provided by the active substances: metronidazole and miconazole nitrate.

The product is intended for local use.

Detailed information about the medicine is contained in the instructions for use. In addition, when visiting a doctor, a specialist can give all the recommendations you need about dosages and methods of using the drug.

Features of application

Experts say that you should not combine a course of therapy with Neo-Penotran vaginal suppositories and an active sex life. The point is not only about the possibility of recurrence of an infectious disease, but also about the peculiarities of the influence of the substances on some contraceptives. The chemical formula of the drug has a negative effect on rubber and latex, damaging products made from these materials.

Remember that antifungal therapy, in case of infection of the genital tract, must be carried out for each sexual partner.

The drug Neo-Penotran and instructions for its use