Omez and De-Nol: how to take together and under what conditions

The drugs De-nol and Omez have different compositions and mechanisms of action. They can be used simultaneously as part of complex therapy for peptic ulcers and some other gastrointestinal pathologies.

The drugs De-nol and Omez can be used simultaneously as part of complex therapy for peptic ulcers and some other gastrointestinal pathologies.

How to choose drugs depending on the acidity level

There are no medications in the world that can restore the functioning of the gastrointestinal tract in one go.
Moreover, they have side effects. You can only take pills with full confidence that they are intended for a specific disease.

This must be done because most drugs have side effects, and this can affect the health of internal organs.

This can be done with the help of doctors, thus it is possible to avoid aggravation of the situation and serious consequences.

Treatment of gastritis

For gastritis and stomach ulcers, you can take complex treatment.

The presence of symptoms such as nausea, vomiting, pain, and abdominal discomfort are clear manifestations of the presence of gastritis.

When treating chronic gastritis, every patient knows a huge number of medications that help eliminate symptoms.

You should not take medications when the first symptoms occur. You can undergo an examination and consult with a doctor, and only then undergo treatment and take various medications together.

Almost any disease of the gastrointestinal tract must be treated comprehensively. Today on the pharmaceutical market there are all kinds of drugs for gastrointestinal diseases. Depending on the symptoms, the doctor prescribes one or another medicine. The most popular among them remain Omez and De-Nol. But which of these two drugs is right for you, only a doctor can determine.

Patient reviews

Due to the availability of a huge number of drugs from different manufacturing companies, reviews from those who have directly encountered this or that product are especially relevant. This applies to both doctors and patients.

Lydia, 21 years old

I have been suffering from ulcers for a long time. On the eve of the summer session, another exacerbation occurred, despite taking all kinds of sedatives. This time, the use of Motilak, Prosulpin and De-Nol was not effective enough. The doctor recommended adding Omez and drinking it together with De-Nol - both drugs half an hour before meals three times a day, one dose. And, lo and behold, within a day I felt much better. After the course of treatment, no new exacerbations or any side effects were observed.

Successful therapy for gastritis requires an integrated approach. Proton pump inhibitors and De-Nol are present in most treatment regimens for this disease. Each of the drugs has an effect on a specific link in pathogenesis. Taking them simultaneously, according to clinical trials, does not in any way affect each other’s action. But I would recommend, if possible, taking them 30 minutes before different meals.

Angelina, 32 years old

The mother began to experience pain and heaviness in her left side. After various examinations, a peptic ulcer was discovered. Therapy consisted of a range of medications. We have been fighting the bacterium Helicobacter pylori for a long time. As a result, De-Nol was prescribed along with antibiotics and Omez for another anti-Helicobacter therapy. Everything was fine, but Omez had too many side effects this time. I had to look for a replacement among other products in this group.

With the participation of a competent attending physician and due patience, it is possible to cause a stable remission of both ulcers and gastritis, as well as other diseases of the digestive system.

I have had chronic gastritis since childhood. During the acute stage, she was treated with standard medications - she took anticoagulants and proton pump inhibitors. Omez was my salvation. However, the doctor said that there would be improvements in just a couple of days, which in itself is strange. And I decided to change doctor. After diagnosis, I was diagnosed with bacterial gastritis, which, naturally, needs to be treated differently. The doctor prescribed me to take De-Nol. I took the course. I forgot about gastritis! It's been 4 years already. A good remedy. Anna, 35 years old

She underwent a thorough medical examination before the planned operation. They examined me from head to toe and found an ulcer. I was shocked, because I never had a stomach ache! The doctor immediately prescribed therapeutic treatment. I was prescribed to take Omez and De-Nol at the same time. Both drugs performed well. No side effects were found. The ulcer was cured in just two months. Yulia, 28 years old

It took a long time to treat a stomach ulcer; De-Nol and Omez were prescribed. There were no improvements. It even seemed to me that it was only getting worse. The doctors were shocked how the medications helped everyone, but not me. By the way, I had a bacterial ulcer. The doctor asked me to stop taking the medications one by one and look at how I was feeling. First I stopped taking Omez and immediately noticed that I felt better. It turned out that the active component of the drug simply did not suit me. Valeria, 52 years old

It is impossible to compare Omez and De-Nol, since the two products have completely different pharmacological properties. To effectively cure an ulcer and choose individual treatment, be sure to consult a doctor. Of course, you can use both drugs at the same time, but you must take some precautions, which your doctor will tell you in more detail.

Omez. Indications for use

1. Ulcers that arise due to stressful situations, improper use of medications. Omez is taken both during the remission stage and in the presence of an exacerbation.
2. Gastritis.
3. Eradication of the bacterium Helicobacter pylori.

You can drink the capsules whole, followed by 1 glass of still water.

You need to take the medicine correctly. It is forbidden to take Omez if you have an individual intolerance, children or pregnant women. Omez is an analogue of the Indian medicine called Omeprazole.

It helps reduce acidity levels and also helps protect the stomach from pathogenic bacteria. Ideal to take with De Nol.

1. Quickly suppresses the production of excess HCl during the day and night, helping to eliminate dyspeptic symptoms.
2. Maintains the pH of the stomach within a range favorable for the healing of peptic ulcers.
3. Increases the activity of some antibacterial agents and has a bactericidal effect on Helicobacter pylori.
4. Relieves pain in chronic pancreatitis by reducing the production of pancreatic enzymes and reducing pressure in the pancreas.

It is produced in the form of capsules and lyophilisate, from which an infusion solution is prepared. The medication does not provoke the development of acid rebound. The initial volume of production of the hydrochloric acid component of gastric juice is restored within a few days after stopping the medication.

• peptic ulcer of the stomach and duodenum;
• complex therapy for Helicobacter infection;
• gastritis;
• esophagitis;
• heartburn;
• gastroesophageal reflux;
• gastrointestinal erosions due to taking NSAIDs;
• ulcerogenic pancreatic adenoma;
• stomach maltoma.

Omez acts as a selective proton pump inhibitor.

Can be used as a prophylactic agent to prevent recurrence of ulcerative lesions.

The drug begins to act soon after administration, the hypoacid effect lasts up to 24 hours.

Medicines should not be taken if you are intolerant to their composition, have severe renal or hepatic dysfunction, or during pregnancy. Nursing mothers should interrupt natural feeding during therapy. This drug combination is used with caution for osteoporosis, anorexia, decreased gastric motility and a tendency to constipation. Age limit: 4 years.

1. Ulcers that arise due to stressful situations, improper use of medications. Omez is taken both at the stage of remission and in the presence of an exacerbation.
2. Gastritis.
3. Eradication of the bacterium Helicobacter pylori.

You can drink the capsules whole with 1 glass of still water.

It helps reduce acidity levels and also helps protect the stomach from pathogenic bacteria. Ideal to take together with De-Nol.

• Gastroduodenitis.
• Gastritis.
• Stomach ulcer.
• Functional dyspepsia.
• Irritable bowel syndrome.

During the treatment period, doctors prohibit drinking alcohol and advise driving with caution. You should not take medications with Vikair, Vikalin, Clopedogrel, Atazanavir due to the development of severe side effects. Taking medications together is contraindicated in the following cases:

• allergy to active or auxiliary components of drugs;
• taking Nelfinavir;
• severe disturbances in the functioning of the kidneys or liver;
• reduced body weight;
• increased fatigue;
• abdominal pain of unknown etiology;
• intoxication of the body;
• disturbance of water and electrolyte balance as a result of prolonged vomiting or diarrhea;
• various swallowing disorders;
• bleeding from the gastrointestinal tract;
• the presence of malignant neoplasms;
• low level of magnesium in the blood;
• reduced supply of vitamin B12;
• osteoporosis.

Omeprazole helps to stop inflammatory processes in the digestive tract and restore ulcerated defects by regenerating the mucosa.

During pregnancy, it is prohibited to take the product. Breastfeeding should be discontinued before use. For respiratory diseases and persistent heartburn, it is necessary to be under the supervision of a gastroenterologist. If nausea, heartburn, vomiting, allergies in the form of skin rashes, headaches, indigestion or other side effects appear during therapy, treatment is stopped.

Taking Rabeprazole

Rabeprazole is a Russian-made proton pump blocker. The active substance is rabeprazole sodium. Available in 10 mg capsules. The drug is completely absorbed after 3.5 hours. The intake does not depend on food; De-Nol and Rabeprazole in the regimen do not interfere with each other. The Indian analogue based on rabeprazole is Khairabezol.

May have side effects:

• decreased appetite, nausea, vomiting, persistent diarrhea or constipation;
• stomatitis;
• bloating;
• dizziness with headache;
• lethargy, drowsiness;
• disturbance of taste and vision;
• temperature increase;
• pain in the back, muscles, joints;
• runny nose, cough, sinusitis;
• allergic skin rash.

Blood tests reveal: increased liver tests, leukopenia, thrombocytopenia. The drug is not used to treat children due to the lack of reliable research results.

De-Nol. Methods of use

It has an astringent effect and helps eliminate bacteria. This is especially true for the bacterium Helicobacter pylori. By reacting with hydrochloric acid, it creates a protective film.

Thanks to this film, the healing process of erosions on the wall of the stomach occurs, which is a good prevention of the development of ulcers and transformation into oncology.

Due to the decrease in pepsin levels, increased resistance to stress occurs.

De-Nol penetrates deep into the mucous membrane, helping to restore it and eliminate excess bacteria. Not absorbed into the gastrointestinal tract. It is excreted from the body through feces.

The drug acts as a selective proton pump inhibitor. The active component used here is omeprazole, a compound with the properties of weak bases, which is activated by acidic exposure in the stomach cavity. The drug irreversibly blocks the enzymatic activity of potassium-hydrogen ATPase, suppressing the final stage of hydrochloric acid production.

It is forbidden to take during pregnancy and lactation, in case of hypersensitivity. It is also not recommended for young children to drink.

It is strictly forbidden to use in chronic, advanced or acute stages of renal failure.

It is not recommended to use De-Nol in large quantities for the treatment of gastritis.

This is because the accumulation of bismuth in the body can lead to problems with the kidneys or central nervous system.

De-Nol is made in the Netherlands. Significant differences in taking a medicine such as Omez from De-nol are in the effect on the main cause of the disease - the bacteria Helicobacter pylori.

Additionally, De-Nol creates a protective coating against damage to the gastric mucosa. It is better to consult a doctor before taking medications.

In almost one hundred percent of cases, the doctor prescribes a course of treatment with De-Nol for stomach ulcers and gastritis. However, these are not the only indications for taking this drug. The list of health problems that tablets can effectively treat is quite extensive:

• duodenal ulcer in different stages;
• gastroduodenitis;
• irritable bowel syndrome (including diarrhea as one of the symptoms);
• dyspepsia;
• peptic ulcer of the stomach;
• peptic ulcer of the duodenum;
• lesions of the gastric mucosa.

Most often, the last of these problems occurs with long-term use of non-steroidal anti-inflammatory drugs.

Before starting a course of treatment with De-Nol for gastritis or peptic ulcers, you need to protect yourself from counterfeits. To do this, you need to study what the tablets should look like.

The manufacturer produces the drug only in tablet form. They have a biconvex shape and are covered with a film shell. Usually the color of the tablets is close to light cream, but minor deviations towards darker or lighter shades are allowed.

The pills are very well protected from counterfeiting due to embossing. It is applied on both sides and consists of an inscription and a graphic design. Some patients treated with De-Nol complained of an unpleasant odor emanating from the tablets. Pharmacists note that this is the norm. Original tablets may emit a mild ammonia odor.

The manufacturer packages the drug in cardboard boxes. Each contains several blisters. They contain eight tablets. On average, a pack contains from seven to fourteen blisters. The maximum number of tablets in a package is one hundred and twelve.

Depending on the severity and nature of the disease, the doctor may prescribe both a minimum course of treatment with De-Nol and a maximum course with a possible repetition in a few months. Based on this, the patient has the opportunity to calculate in advance which package of tablets he will need.

Storage rules

Only a dry place, out of direct sunlight, is suitable for storing the drug; the room temperature should not exceed 25°C, otherwise the medicine may soon become unusable.

It is worth considering that storing it in a refrigerator or in a damp room can affect the loss of properties of the drug. It is best to keep De Nol in a special first aid kit, which will be kept out of the reach of children.

You need to pay attention to the appearance of the tablets. There should be no mechanical damage or punctures, otherwise it is better not to use such medicine. A change in color and odor may also indicate non-compliance with storage conditions, so such tablets are also not suitable for oral administration. In general, De Nol does not require special storage conditions. It is important to maintain temperature conditions.

Please note that the shelf life of the tablets is 48 months.

According to the instructions for use, the treatment regimen is as follows:

1. For the treatment of children from 4 to 8 years of age, tablets are prescribed at the rate of 8 mg per 1 kg of the child’s body weight. The average therapeutic dosage should be divided into two doses during the day.
2. If the child's age is from 8 to 12 years, the average dosage is 1 tablet twice a day.
3. If the child has reached the age of 12 years or an adult patient is being treated, the drug is prescribed at the rate of 1 tablet 3 or 4 times a day.
4. For gastritis with high acidity, you should take tablets 30 minutes before meals. De-Nol capsules are washed down with plenty of clean filtered or boiled water.
5. The full therapeutic course for gastritis is 5 – 8 weeks. The final decision on how long De-nol should be taken is made by the attending physician. In some cases, a course is prescribed to prevent relapse of the disease.
6. When the course of treatment with the drug is completed, it is not recommended to take medications containing bismuth for the next two months.

Instructions for use recommend taking the tablets 30 minutes before starting a meal. The patient takes three tablets before meals and the last tablet should be taken at night.

An alternative treatment regimen is to take 2 tablets before breakfast or before dinner. It is strictly forbidden to chew the tablets. It is possible to drink only non-carbonated clean water. Do not take the medicine with tea, milk or coffee. The action will reduce the effectiveness of treatment.

Restrictions on use

It is not recommended to use De-Nol in large quantities for the treatment of gastritis.

It is also important to maintain time and not take De-Nol 30 minutes before or after meals. The treatment regimen lasts for a maximum of 2 months.

De-Nol is made in the Netherlands. Significant differences in taking a medicine such as Omez from De-nol are in the effect on the main cause of the disease - the bacteria Helicobacter pylori.

Additionally, De-Nol creates a protective coating against damage to the gastric mucosa. It is better to consult a doctor before taking medications.

What's better,

Taking Omez or De-Nol - which is better for stomach diseases? It is impossible to give a definite answer to this question. Reviews about these drugs are good, but there are also people who are dissatisfied.

Those who have ever treated a stomach ulcer or gastritis are familiar firsthand with the drugs De-nol and Omez - the favorite drugs of gastroenterologists.

Let's try to figure out what is better - Omeprazole or De-nol, when they are prescribed, how they differ from each other, whether you can take only one of them or you can drink them together.

These medications are the most popular drugs for the treatment of gastritis and other pathologies of the digestive organs. The effectiveness of their use has been proven by many years of gastroenterological practice.

They can be used individually or in combination with other drugs to treat acute conditions or prevent exacerbations.

In this case, drug therapy is determined by the attending physician based on:

• forms of the disease;
• patient's age;
• concomitant diseases.

Omeprazole is the active substance of Omez. By entering into a chemical reaction with the acidic environment of the stomach, it inhibits the activity of the proton pump, an enzyme that stimulates the secretion of hydrochloric acid.

The effect of the drug lasts for 17-24 hours. The maximum effect develops after 4 days of taking the capsules.

Suppresses the activity of the pathogenic bacterium Helicobacter pylori.

Description De-nol

Refers to bismuth-containing gastroprotectors.

Entering into a chemical reaction with the contents of the stomach, it forms complex compounds (white film) on the surface of mucosal defects - ulcers and erosions. Activates the production of mucus, prostaglandin E, bicarbonate.

Increases the resistance of mucous membranes to the irritating effects of enzymes, hydrochloric acid and bile acids. Heals defects in the mucous membrane of the walls of the stomach, esophagus and intestines.

Drug differences

It is not entirely advisable to compare these drugs, because... they belong to different pharmacological groups and have different mechanisms of action.

It is advisable to use De-nol for:

• dyspeptic symptoms (diarrhea, heartburn, sour belching, nausea, epigastric pain);
• peptic ulcer of the duodenum and stomach;
• irritable bowel syndrome;
• duodenitis;
• gastritis;
• helicobacteriosis.

Omez is prescribed for:

• gastroesophageal reflux disease (GERD);
• peptic ulcer of the stomach and duodenum;
• hypersecretion of hydrochloric acid;
• infection with the bacterium Helicobacter pylori (in combination therapy).

The drugs can be taken together.

Their compatibility is positive, i.e. They:

• enhance each other’s therapeutic effect;
• accelerate the onset of the effect;
• inhibit the growth of bacteria that cause gastropathy;
• eliminate symptoms of diseases faster.

Thus, joint therapy is aimed at all parts of the pathology:

• bacteria;
• excessive production of hydrochloric acid;
• dyspeptic symptoms;
• erosive and ulcerative lesions of the mucous membrane.

There are a number of contraindications for the use of De-nol:

• period of breastfeeding and pregnancy;
• severe renal dysfunction;
• children under 4 years of age;
• individual intolerance to the components of the drug;
• taking other bismuth-containing medications.

Restrictions on taking Omez:

• children under 2 years of age;
• hypersensitivity or intolerance to the ingredients of the drug;
• taking certain medications (posaconazole, erlotinib, nelfinavir, atazanavir).

Both drugs are included in treatment regimens used for pathologies of the digestive tract, including those associated with Helicobacter pylori.

Before treating helicobacteriosis, it is necessary to undergo a medical examination, which will reveal the presence of a pathogenic bacterium. To do this, a biopsy and blood tests are taken. If the result is positive, the doctor prescribes antibiotic therapy.

Special regimens include antibiotics of various pharmacological groups.

The most commonly used schemes are:

• triple therapy method - take De-nol or Omez together with the antibiotics Amoxicillin and Clarithromycin. Metronidazole can be used instead of Amoxicillin;
• The quadruple therapy method is a backup technique when De-nol is taken together with Omez, Metronidazole and Tetracycline.

There are many other variations of antimicrobial therapy, which include other drugs: Furazolidone, Josamycin, etc.

Patient reviews

Patients who took De-nol and Omeprazole generally speak well of them.

The advantages of De-nol are:

• no serious side effects;
• positive effect of therapy;
• long-term preventive effect;
• Available in all pharmacies;
• availability of large and small packaging.

Disadvantages of a gastroprotector:

• it is required to observe the interval before taking food and other medications;
• high price;
• contraindicated for pregnant and nursing mothers;
• ineffective as a stand-alone remedy; other medications are required.

The advantages of Omez are considered:

• affordable price compared to other stomach medications;
• Suitable for young children, pregnant and lactating women;
• no serious side effects;
• quickly relieves heartburn and pain;
• can be bought at any pharmacy;
• There are packs of 10 and 30 capsules.

Flaws:

• cannot be taken for a long time;
• in some cases it does not help without other medications.

Doctor's recommendations

Omez and De-nol are good drugs that have been protecting the health of the gastrointestinal tract for decades. Their effectiveness has been confirmed by clinical studies and daily medical practice. But even the most reliable means can cause harm.

The appropriateness of prescribing such drugs is determined by the doctor. At the same time, he evaluates the symptoms and the results of examinations, which help determine the type of pathology.

It will not be possible to establish a diagnosis on your own, because there are several types of gastritis:

• with high acidity;
• with low acidity;
• atrophic;
• erosive, etc.

The same symptoms may indicate different forms of the disease.

Therefore, the best decision for stomach pain and other dyspeptic syndromes is to consult a gastroenterologist, who, after an examination, will determine what means to treat gastritis.

Health November 30, 2017

Gastric diseases such as gastritis, ulcers, pulpitis are widespread among people of all ages. There are enough medications prescribed by doctors for exacerbations and for their prevention. Many of them can be used in complex treatment, so the question of which is better “Omez” or “De-Nol” often arises among patients.

Stomach diseases

When ingesting food, the cells lining the inner mucous surface of the human stomach are exposed to the irritating action of physical and chemical factors. Optimal conditions for the normal digestion of incoming products are created by the active work of glands and cells that produce hydrochloric acid, which also play a protective role against harmful bacteria.

When an infection enters the stomach or is negatively affected by irritating factors, inflammation of the mucous membrane occurs. In this case, the cells and glands begin to produce too much hydrochloric acid. The consequence of this imbalance is a violation of acidity with its excessive production and a disorder of the digestive system.

People of any age and social status are susceptible to stomach diseases, and they are treated with various methods. The most common diseases are erosive and ulcerative gastritis and stomach ulcers.

Gastritis is a disease in which the functioning and secretory function of the stomach is impaired, accompanied by inflammatory processes of its mucous membrane, intestinal spasms and constipation. The disease often occurs against the background of increased stomach acidity. Treatment of gastritis is complex, one of its conditions is following a strict diet and taking medications.

Peptic ulcer disease most often occurs due to chronic gastritis of the stomach. Its aggravation occurs under the influence of several negative factors: overwork, lack of sleep, prolonged stress, smoking and drinking alcohol, unhealthy diet, etc.

In the treatment of gastritis and stomach ulcers, gastroenterologists widely use the drugs Omez and De-Nol. Treatment carried out with their help can reduce the unpleasant symptoms of diseases, reduce the negative effect of acid on the walls of the stomach and create a protective film at the site of erosive formations.

Helicobacter Pylori is a harmful bacteria that causes the disease helicobacteriosis, which contributes to the appearance of duodenal and stomach diseases: gastritis and ulcers.

The discovery of these bacteria aroused great interest among medical scientists, who still devote their research to them.

It was found that helicobacteriosis is present in 70% of the world's population, but with good immunity, the bacteria cannot multiply much.

Under unfavorable conditions, which include stress, infections, bad habits and bad food, their effect can affect not only the gastrointestinal tract, but also the liver, pancreas and heart.

They contribute to the appearance of bronchial asthma, disorders in the endocrine and hematopoietic systems.

Drug differences

It is not entirely advisable to compare these drugs, because... they belong to different pharmacological groups and have different mechanisms of action.

For convenience, we offer a visual table of comparative characteristics:

Is it possible to take De-Nol and Omeprazole at the same time and which drug is better?

Any doctor in the field of gastroenterology will confirm that gastritis, ulcers, or any other pathology of the gastrointestinal tract must be subject to complex therapy, otherwise the treatment will become ineffective.

The main purpose of Omez is aimed at inhibiting the production of gastric secretions. The active components of the drug produce a protective film, which has a beneficial effect on the mucous membrane of the organ.

De-Nol, in turn, is also prescribed for the treatment of diseases of the gastrointestinal tract. After a few days of taking De-Nol in complex therapy, the components of the drug produce substances that form a protective film on the gastric mucosa, thus preventing the bacteria Helicobacter pylori from developing.

To prevent diseases, experts recommend using De-Nol.

These two remedies can be taken together. This is evidenced by the recommendations of doctors. But you still need to strictly monitor the duration of taking medications that only a doctor prescribes.

You should not take medications when the first symptoms occur. You can undergo an examination and consult a doctor, and only then receive treatment.

The drug belongs to the group of gastroprotectors that are used in the treatment of peptic ulcers and gastritis. Its active substance is a complex bismuth salt. The product has the following therapeutic effects:

• forms a protective film on the inner walls of the stomach, which prevents the development of further lesions of the mucous membranes;
• stimulates the production of mucus (mucin), which is a natural defense against the aggressive effects of digestive juices;
• reduces acidity, reduces the negative effect of peptin, a digestive enzyme, on the stomach walls;
• improves blood supply, stimulates metabolic processes;
• suppresses the activity of Helicobacter pylori, reducing their mobility.

Thus, the effectiveness of the drug in the treatment of gastritis and ulcers is undoubted. In addition, the drug may be prescribed for the treatment of irritable bowel syndrome.

It is possible to combine medications. At the same time, their effect is enhanced. The drugs are taken in the presence of reflux esophagitis, dyspepsia, gastritis, ulcers of the duodenum and stomach or inflammation of their membranes, functional digestive disorders in the intestines. Medicines are taken to treat or prevent diseases.

Omeprazole and De-Nol are medications that help in the treatment of diseases of the digestive tract.

Treatment of stomach ulcers and gastritis occurs through complex treatment. The complex includes treatment with medications, diet and traditional medicine methods.

Many people believe that the effects of these drugs are the same, but this is not true.

There is a treatment regimen for stomach ulcers or gastritis. De-Nol is considered to be one of the main and most common medications, but there are a number of other medications that can fight bacteria.

If there is a severe exacerbation, it is recommended to take Omeprazole together with De-Nol. But at least an hour should pass between taking these two medications.

This is due to the fact that De-Nol significantly reduces the healing properties of Omeprazole. But only a gastroenterologist can determine the compatibility of these drugs during treatment.

Contraindications and side effects

Medicines have different pharmacological characteristics, but they combine well, complementing each other. Their parallel use creates optimal conditions for the healing of erosions and ulcers of the mucous membrane in the gastroduodenal zone, prevents their reappearance, eliminates severe symptoms and brings the onset of remission closer.

However, there are contraindications to the combined use of De-Nol and Omeprazole. These include pregnancy and lactation. During clinical trials, it was found that De-Nol components can cause gene mutations and, as a result, the development of pathologies in the fetus. And during breastfeeding, the components of the drug, primarily bismuth compounds, penetrate into the baby’s body with milk and can damage the kidneys and nervous system.

The effect of using Omeprazole and De-Nol together is much higher than from using them separately. However, it should be remembered that self-medication with a complex of these drugs is absolutely impossible. Only a gastroenterologist can draw up the correct drug therapy regimen. In addition, both medicines can be purchased at a pharmacy only with a doctor’s prescription. Uncontrolled use of drugs in this group can lead to untimely diagnosis of the development of tumors in the digestive organs.

The maximum duration of taking De-Nol should not exceed two months. Otherwise, a high concentration of bismuth in the body can cause serious impairment of kidney function.

Comparison of drugs De-Nol and Omez

What is the difference between Omez and De-Nol? As already mentioned, these are drugs from different pharmacological groups. Omez is a proton pump inhibitor, that is, a drug that reduces the amount of hydrochloric acid in the stomach.

De-Nol is a restorative and antibacterial agent, that is, a gastroprotector. Therefore, it is difficult to compare these drugs, they act differently and can be prescribed at the same time.

De-Nol has the following effects:

• gastroprotective;
• regenerating;
• bactericidal (active against Helicobacter).

Omez is an antacid, its pharmacological action:

• reduction of hydrochloric acid production;
• suppresses the growth of pathogenic microflora by creating negative living conditions for them.

The active substance of De-Nol is a complex bismuth salt. This substance has a healing and regenerating effect. In addition, the product exhibits antibacterial activity against Helicobacter pylori infection. The active ingredient of Omez is omesoprazole or 5-methoxy benzimidazole. Antacid agent.

Release form

The release forms of De-Nol are tablets. The drug is produced packaged in blisters of 8 pieces. One pack contains from 7 to 14 blisters. Omez is sold in capsule form; different forms contain 20 or 40 mg of the active substance. Capsules are packaged in blisters of 10 pieces. The package usually contains 2 blisters.

Medicines are prescribed for the treatment of gastrointestinal pathologies accompanied by excess acidity. Indications for use:

• inflammation and erosive and ulcerative lesions of the gastric and duodenal mucosa;
• eradication of H. pylori (in combination with antibiotics);
• reflux esophagitis;
• dyspeptic disorders due to hyperacidity of gastric juice.

Often, a gastroenterologist prescribes taking De-Nol and Omez at the same time. These drugs belong to different pharmacological groups, their actions complement each other. How to take De-Nol with Omez?

It is very important to take these medications correctly, as taking them incorrectly can result in less effective treatment. Therefore, you should definitely check with your doctor about how to properly take De-Nol and Omez together.

The dosage of the drug is determined by the doctor, who must also recommend a treatment regimen. The standard treatment regimen with De-Nol and Omez is as follows:

• In the morning on an empty stomach you need to take an Omez capsule;
• after half an hour you need to take a De-Nol tablet;
• in another half hour you will be able to have breakfast;
• the second and third De-Nol tablets must be taken half an hour before lunch and dinner, respectively;
• The fourth De-Nol tablet is taken at night.

When a Helicobacter pylori infection is detected, antibiotics are included in the treatment regimen with Omez and De-Nol. As a rule, two antibacterial drugs are prescribed. The course of treatment with antibiotics is 7-10 days, it is necessary to take De-Nol and Omez longer, the course of treatment is 1-2 months.

Side effects

Omeprazole (active substance) has a specific effect on the enzymes of stomach cells. The drug quickly reduces the secretion of hydrochloric acid - the effect appears within an hour and is maintained throughout the day. The medicine eliminates heartburn, belching and a feeling of heaviness in the stomach.

Omez is prescribed for the following conditions:

• peptic ulcers and erosive-ulcerative esophagitis;
• ulcerative processes associated with taking NSAIDs;
• gastroesophageal reflux disease;
• systemic mastocytosis;
• pancreatitis.

Omez is prescribed for peptic ulcers and erosive-ulcerative esophagitis.

The medicine is available in the form of gelatin capsules and powder for diluting a solution (intravenous administration is possible).

De Nol is well tolerated, but side effects may occur: nausea, vomiting, constipation or frequent bowel movements. With increased sensitivity, skin rashes or itching appear.

Long-term use of large doses can provoke the development of encephalopathy (bismuth can accumulate in the central nervous system).

Side effects when using omeprazole manifest themselves in the form of headache, nausea, dizziness, abdominal pain, and flatulence. Possible disorders of the hematopoietic organs (leukopenia, thrombocytopenia) and the musculoskeletal system (joint or muscle pain). Sometimes allergic reactions occur: itching, urticaria, bronchospasm.

When is it prescribed to take Omez?

The drug market offers a very large number of drugs that are necessary for the treatment of gastritis.

But not all of them have a positive effect on recovery. A large number of doctors recommend in this case to opt for taking a medicine such as Omez.

It is this that helps eliminate acute symptoms of the disease in a short period of time.

Side effects from taking this medication are minimal. They are aimed at producing gastric juice in limited quantities.