There are many different medications available for hypertension. We will look at the instructions for using Andipal: at what pressure can this medicine be taken, is the drug really that effective?
Andipal is classified primarily as an antispasmodic and analgesic, the effect of which in hypertension helps to dilate blood vessels. In addition, the drug contains psycholeptic components that help relieve headaches and dizziness that occur with high blood pressure. Main active ingredients: bendazole, papaverine, metamizole sodium, phenobarbital.
The drug is a whitish-yellow tablet. This product is always available in one form with the same concentration of active ingredients.
The average price of the drug usually does not exceed 100 rubles per pack. Today, Andipal is considered a rather outdated medicine against hypertension and migraine. In addition, due to the presence of phenobarbital, this drug may affect the patient's mental state. It is also worth considering a large number of possible side effects and contraindications.
The active ingredients in the drug help relieve spasm of blood vessels in the brain and the body as a whole. Due to this, the blood vessels dilate, the pain of migraines goes away, and blood pressure decreases. The analgin included in the composition complements the analgesic effect. In addition, the drug has a sedative effect, eliminating the effect of high blood pressure on a person’s emotional state.
At the moment, Andipal is practically not prescribed, preferring to use more modern and safe means. However, this drug is still quite common; it is used in the vast majority of cases by older people who are simply accustomed to this drug. Therefore, if there is no other, more suitable remedy at hand and Andipal is tolerated without problems, it can be used after reading the instructions.
Andipal can also be taken together with other drugs for the treatment of hypertension: beta-blockers, diuretics, and other antispasmodics. In this case, the hypotensive effect will increase. When taking the medicine simultaneously with tonic drugs, its effect will weaken.
Important! It is worth remembering that such drugs should not be taken frequently. If high blood pressure bothers you regularly, you should consult a doctor to find out the cause of this condition and choose appropriate therapy.
General information about the drug: its composition and properties
Andipal is a long-known drug that contains 0.25 g of metamizole sodium (the main active ingredient of Analgin tablets) with analgesic and antipyretic properties, 0.2 g of phenobarbital with a sedative effect and 0.2 g of papaverine hydrochloride and bendazole (dibazole), distinguished by their antispasmodic properties, reducing the tone of the smooth muscles of our internal organs and dilating peripheral vessels.
Composition, release form
“Andipal” is used for high blood pressure and more. It helps relieve cramps (during menstruation), eliminate pain syndromes of various types. It is also used for increased anxiety. Pharmacists explain the widespread use of the drug in question by the large list of active ingredients in the composition of this drug. The drug is produced in the form of tablets. They are characterized by a white, slightly yellowish color.
Andipal tablets consist of many active elements:
- Metamizole sodium, analgin. Pharmacists consider this component as the main one. Its purpose is to eliminate pain and inflammation.
- Bendazole (dibazole). This substance is used to lower high blood pressure (BP). It successfully lowers it, but the effect is usually short-lived. Bendazole also has a calming effect.
- Phenobarbital. The substance is classified as a sedative. It also has an antispasmodic effect, although it manifests itself very weakly.
- Papaverine hydrochloride. This component helps relieve cramps that occur during menstruation. It lowers blood pressure that is not too high, reduces vascular tone, and helps normalize the heartbeat.
The composition also contains other components that play a supporting role. These include:
- stearic acid,
- talc,
- starch.
One tablet has a mass of 0.37 g. The dragees are placed in cellless contour packaging of 10 pieces.
Indications for use
Considering the complex composition of the drug "Andipal", the instructions prescribe taking it to quickly relieve high blood pressure. This action is safe only if you make sure that the headache is caused by high blood pressure before taking it.
For hypotensive patients and people with unstable blood pressure levels, the drug can increase symptoms of low blood pressure and even lead to serious problems with brain functioning. Doctors still have not developed a consensus on the use of Andipal. Some experts advocate occasional use of this medication to relieve unbearable pain. Other doctors are inclined to prescribe the drug as a course. Anti-pressure tablets "Andipal" will not only help normalize the level of blood pressure that has increased as a result of arterial hypertension, but will also relieve a migraine attack and improve the condition of VSD (vegetative-vascular dystonia).
Previously, this drug was used in the complex treatment of hypertensive crises. Today medicine has more effective means of treating this disease. However, the medicine Andipal for blood pressure remains a popular first aid remedy, especially among people with low incomes, and this is facilitated by the mostly positive reviews about it. The vasodilating and analgesic, antispasmodic and sedative properties of the drug “Andipal” help relieve pain syndrome expressed by spasm of the peripheral arteries, gastrointestinal tract (their smooth muscles), as well as cerebral vessels. The drug can be taken at a time, for attacks of headaches (including migraines), gastrointestinal spasms, pain in the premenstrual period - 1 or 2 tablets no more than 3 times a day. A diagnosis of hypertensive type VSD recorded by a doctor can be treated according to a regimen where therapy lasts from 5 to 10 days.
Instructions
How to take this drug correctly? The tablets are taken orally with a small amount of plain water. You should not take the medicine for more than 7-10 days in a row. If your blood pressure does not decrease, you should definitely contact a cardiologist. Children under eighteen years of age should not take Andipal.
Adults are usually prescribed 1-2 tablets 2-3 times a day. It is advisable to check the required amount of the drug with your doctor: the final dosage may depend on the person’s weight and the severity of the disease.
Do you take this drug before or after meals? The official instructions for use do not specify, so this is not of particular importance. The main thing when taking such medications is to maintain equal intervals between using the drug so that the effect is as smooth as possible and there are no pressure surges or return of pain.
Features of the drug
No matter how positive the reviews about our medicine are, all the nuances of taking the drug “Andipal” (for what pressure - high or unstable) must be agreed with a specialist. There are often cases when this medicine relieved a severe headache with a blood pressure of 150/50, normalizing it. At the same time, systolic (upper) pressure decreased, and diastolic (lower) pressure reached normal levels.
It is up to the doctor to decide whether Andipal is needed, at what pressure to take it and for how long. The presence of phenobarbital has a mild narcotic effect, due to which the level of adrenaline in the blood decreases, so it can cause addiction to the drug.
Contraindications
It is worth noting that Andipal has a fairly large list of contraindications. First of all, it cannot be used in case of individual intolerance to the components of the drug.
Also, this drug is prohibited for various blood diseases, kidney and liver dysfunction, myasthenia gravis, porphyria, and a number of other pathologies of the cardiovascular system. To completely eliminate contraindications, it is recommended to consult a specialist before starting to use the product.
You should not use Andipal during pregnancy; however, only the first trimester of pregnancy is considered a strict contraindication. During the second and third, you can use this drug after consulting a doctor, if it is not possible to use safer means.
Important! During breastfeeding, taking the drug is completely prohibited.
Compatibility with other drugs and ethanol
When ingesting nitrates or slow calcium channel blockers, ganglion blockers or beta-blockers, as well as myotropic antispasmodics or diuretics (including hypothiazide, furosemide), you must agree with your doctor about the possibility of using Andipal tablets. This combined inexpensive drug significantly reduces blood pressure and enhances the hypotensive effect of the listed drugs.
Due to the increased risk of adverse reactions, special caution should be observed when prescribing narcotic analgesics while taking the drug Andipal. What kind of pressure does it help with? Doctors give a clear answer - from high. Any adsorbents, as well as astringent and enveloping dosage forms, reduce the ability of Andipal to be absorbed from the gastrointestinal tract. It is categorically unacceptable to use this drug with alcohol - the consequences of such a “duet” can be sad: severe poisoning, internal bleeding, pressure surges, stroke, stomach ulcers and shortness of breath. During treatment with Andipal, taking any doses of alcohol is prohibited.
Pharmacological action, pharmacodynamics, pharmacokinetics
Let's look at what Andipal tablets can be used for. The medication has the following therapeutic effects:
- antispasmodic,
- anesthetic,
- calming,
- vasodilator.
Under the influence of the drug, there is a decrease in blood pressure and an improvement in collateral circulation. Thanks to the unique combination of components such as papaverine hydrochloride, dibazol with analgin, the analgesic effect of the tablets becomes stronger. This is especially true for the treatment of identified sinuses and headaches.
Phenobarbital in the composition of the drug provides its sedative effect, as well as enhancing the effectiveness of other active substances. This substance also exhibits a hypnotic effect, while suppression of foci of pathological excitation in the cortex of the cerebral hemispheres occurs.
Experts often prescribe Andipal to patients who have been diagnosed with early stages of hypertension. A decrease in blood pressure is achieved due to vasodilation. Andipal is also capable of exhibiting an antiepileptic effect.
Precautions: Side Effects
When choosing the drug “Andipal” for treatment (for what pressure, we know), you should take into account that the following may occur: nausea, allergic phenomena (even with anaphylactic shock), problems with bowel movements (constipation). With long-term drug therapy (more than 7 days), it is necessary to monitor the peripheral blood picture and liver functionality.
The presence of analgin in the medicine can cause leukopenia, phenobarbital - a sedation effect (ataxia or depression). During the treatment period, it is necessary to refrain from performing work that requires increased concentration or hazardous activities (for example, driving). The speed of psychomotor reactions during this period is significantly reduced.
Overdose
Exceeding the dosage specified in the annotation may cause poisoning. Signs of an overdose are:
- dizziness,
- severe drowsiness,
- collapsed state.
In this case, first aid is required, represented by gastric lavage and the use of “Activated carbon”. The doctor also prescribes symptomatic treatment.
Can pregnant women take the drug?
To understand whether Andipal can be taken during pregnancy, let's consider its effect on the mother and the fetus.
- High blood pressure is a fairly common condition for expectant mothers. Therefore, it is not surprising that one of the drugs prescribed to pregnant women is Andipal, which lowers blood pressure and relieves headaches. Almost immediately after administration, the components included in the medicine relieve unpleasant symptoms and bring long-awaited relief.
- However, you should remember how phenobarbital ingested by a pregnant woman affects the fetus. It inhibits the functioning of the unborn child’s brain and slows down its development when taken for a long time. There is a high probability that the patient will have a baby with a disease such as cerebral palsy.
- When prescribing a drug, the doctor is obliged to warn the pregnant woman about possible negative consequences and the risk of developing pathologies. Another problem should be mentioned here: many drugs that have a similar effect have an even more negative effect on the developing fetus, and some even lead to the death of the baby in the womb.
- That is why, of all the possible drugs, Andipal is usually prescribed. It must be taken under the close supervision of a specialist.
- Following the contraindications for use, Andipal is not prescribed for renal failure, liver and blood diseases. Sometimes patients experience individual intolerance to this drug, which should also be excluded.
Andipal's duration of action, special instructions
Most people who have taken this drug note that the pressure begins to gradually drop, and the pain syndrome completely disappears approximately thirty minutes after taking Andipal.
The therapeutic effect lasts for a long period of time (4-6 hours). With prolonged use, you need to monitor your blood condition.
You cannot self-medicate. You must follow the recommendations specified in the instructions.
Andipal for children
Andipal is contraindicated for children. Prescribing Andipal to children is possible only at the age of 14 years. An earlier age of the child is a contraindication. Phenobarbital, which is part of the drug, has a negative effect on the development of brain cells. When Andipal is systematically taken by children, the phenomenon of mental failure may occur. Before prescribing Andipal to children, the doctor should carefully familiarize himself with all existing additional diseases in the child and try to find an alternative treatment.
Analogs
To eliminate the conditions described above, doctors prescribe analogues of the medication in question. But it is important to take into account that other drugs have distinctive contraindications and dosages of use.
Among the popular analogues we note:
- "Analdim."
- "Captopril."
- "Quattrox".
- "Papazol."
- "Celebrex."
- "Kofalgin."
Analogues of the drug in question for high blood pressure are an order of magnitude higher. An analogue with greater effectiveness is “Captopril” (ACE inhibitor). It copes faster with lowering blood pressure and has a hypotensive effect. This medication has a milder effect.
Barbiturates and once - a threat
Women who are used to saving themselves with Andipal sometimes continue to take this drug (drug) during pregnancy, believing that a one-time dose will not harm the baby.
Those expectant mothers who do not rely on chance and are interested in whether it is possible to take medication during pregnancy know that it is not worth using this remedy not only because of the analgin.
One of the components of the medicine, phenobarbital, is categorically not recommended for women during pregnancy, because it inhibits the activity of the nervous system. How do you like this side effect?
At the stage of the formation of the nervous system, this is fraught with irreversible changes in the development of the central nervous system, up to a serious lag in intellectual development. Since the nervous system develops throughout pregnancy and after the birth of the baby, taking this medicine at a later stage is dangerous.
Negative Impacts
The use of a medication may cause negative effects, including:
- Hypotension.
- Allergic responses.
- Drowsiness.
- Impaired kidney function.
- Nausea.
If these undesirable reactions occur, the dose used should be reduced or therapy with this drug should be completely abandoned.
Are carrying a baby and andipal incompatible?
Is it possible to take a drug (drug) while carrying a child? The instructions explicitly prohibit use; pregnancy (at any stage!) and lactation are contraindications.
Two but...
“But” first: Yes, yes, you can find instructions where they will write in the contraindications for you the first trimester, and not the entire period of pregnancy. But we don’t recommend “buying into” this. The formation of the main organs and systems actually occurs just in the first half of gestation. But usually this means the entire pregnancy, and especially the first trimester.
“But” second: The instructions prohibit taking Andipal while carrying a baby (at any stage!). But sometimes doctors have to deviate from the instructions when it comes to the patient’s life.
Because of their education and experience, they know when and how much to retreat. And they prescribe the drug with caution and supervision to save the patient's life.
If your doctor has prescribed this drug to you and you are unsure about the need to take it, consult with another doctor. But do not take this medicine yourself!
When do we treat?
Andipal is drunk when experiencing spastic pain (spasm of blood vessels located in the brain, biliary or renal colic, migraine). Outside of pregnancy, Andipal is a good affordable drug to combat spontaneous attacks of hypertension, thanks to its composition:
- sodium metamizole (analgin) - an anesthetic with an antipyretic and weak anti-inflammatory effect;
- phenobarbital - an anticonvulsant with a pronounced sedative effect (belongs to the group of barbiturates);
- benzadol (better known as dibazol) - a vasodilator and myotropic drug with an antispasmodic effect;
- hydrochloride - an antispasmodic (relaxes spasmodic muscles) drug.
When using the drug accurately (precisely on target), that is, correctly, you can get an excellent hypotensive and analgesic (eliminates) effect. Dibazole and papaverine are a strong combination for relaxing the smooth muscles of the vascular wall and reducing pressure. But while carrying a baby, it is better to use gentle means.
During pregnancy and in the last 6 weeks, do not “indulge” in this medicine under any circumstances! Even if for some reason you were prescribed it in the middle of pregnancy. After all, 2 out of 4 components (phenobarbital and analgin) are avoided by obstetricians at all costs during pregnancy.
If there is a need to take drugs for blood pressure, consult a gynecologist. Most likely, he will replace your drug with a safer one. And it is likely that 2 tablets or an intramuscular injection of Nosh-pa will be enough for you to normalize your condition.
If you have severe hypertension, the doctor will still select a medicine with a minimum of harm to you and the baby. Particular care must be taken when taking Andipal during pregnancy.
For example, its component, Metamizole (), is prohibited in some countries altogether, since there is a risk of developing agranulocytosis (few lymphocytes due to the fact that there are many granulocytes, such people have a high risk of developing viral and bacterial infections).
It is believed that agranulocytosis can develop even if you take just one tablet. Instead of analgin, it is recommended to take safer drugs ().
Andipal during pregnancy - reviews
Unfortunately, Andipal only removes the symptoms of the disease, but does not contribute to its treatment. Therefore, women try to avoid taking this drug. But when it is impossible to endure pain and suffer from high blood pressure, pregnant women still take the Andipal tablet.
In each individual case, the effect of Andipal is different. Someone writes that it normalizes blood pressure well and helps with headaches. There are also those for whom Andipal did not help at all.
Women's opinions about Andipal are predominantly negative. They are afraid to take it after studying the list of side effects, so they are looking for more acceptable treatment options.
By drawing conclusions from the available information, you can get a very clear answer to the question of whether Andipal can be taken during pregnancy. It is better not to take this drug in this important period of a woman’s life if there is an opportunity to use an alternative and safer drug. But this does not mean that you need to ignore the pain syndrome, because it also harms the baby. Just if you feel unwell, contact your doctor and together make a decision on how to get rid of pain or hypertension.
No Analgin! Why?
It is prescribed only for vital signs. Considering this alone, you should avoid taking Andipal during pregnancy. The next component is Analgin.
The World Health Organization does not recommend the drug for use at any stage of pregnancy, because it can negatively affect the development of blood vessels and the heart of the fetus.
The effect of the drug is especially noticeable in the early stages. At the end of gestation (gestation), Algin is not recommended because it affects the blood coagulation system. And its use can cause postpartum hemorrhage.
Side effects, conditions of sale and storage
Reviews of Andipal tablets from most patients are positive, but many note a number of symptoms that arise when using the drug. These include constipation, allergies, nausea, drowsiness, nephritis, and change in urine color. Long-term use leads to leukopenia, thrombocytopenia, and agranulocytosis.
You can purchase the medicine without a prescription. For storage, choose a dark, dry place out of reach of children. The air temperature in the room is not higher than 30 degrees. Be sure to pay attention to the expiration date, after which the drug cannot be taken.
When will anidipal help?
Its purpose is indicated for various situations that form a specific symptom complex.
- Taking it will eliminate headaches. However, it matters what causes the pain symptom. It will help only when the occurrence of pain is due to a state of spasm. By relieving the spasm, the pain also disappears. If the pain is associated with any mechanical effect, taking it will be useless. He won't help. But with high blood pressure, when blood vessels are subject to spasm, you can take it.
- Pain associated with spasms of the digestive organs. It will only eliminate the pain, but not the reason why the organs are undergoing spasm.
- Andipal is able to reduce blood pressure. Its use will be effective only in the initial stages of hypertension, when the pressure numbers are not high. But it will not be possible to cure the disease itself. There will be no effect even if it is used for a long time. To reduce blood pressure, it is recommended to take it once. Reception can be carried out if systolic pressure does not exceed 160 units. At higher numbers, it is useless to take it, since taking it will not have the desired effect. Such indicators are borderline for its use.
Interaction with other drugs
The use of Andipal with other medications has the following effects on the body:
- A rapid decrease in pressure is observed after simultaneous use of the tablets in question with calcium antagonists, myotropic drugs, beta blockers, and diuretics.
- Poor absorption of the drug is observed if Andipal and sorbents and medications that exhibit an astringent, enveloping effect are taken together.
- An increased risk of side effects is possible when combining tablets with opioid analgesics.
Causes of headaches during pregnancy
A headache in a pregnant woman can be a consequence of her emotional experiences (not everyone perceives their new condition equally calmly), and the cause of painful sensations can be:
- lack of sleep;
- low blood sugar;
- dehydration of the body;
- weather dependence;
- stress;
- excessive passion for drinks containing caffeine;
- high blood pressure.
Each of these points is dangerous in its own way and none of them is undesirable for a pregnant woman. But of all the above, the most severe and unbearable headache is associated with blood pressure.
In the third trimester, the cause of high blood pressure can be preeclampsia (a severe form of toxicosis), and the head can also hurt due to spinal tension and worsening posture.
In any case, symptoms (headache, abdominal cramps) must be eliminated.
Urgent help in case of excessive drug intake
If there are clear signs of deterioration in the health of a person who has taken Andipal tablets, poisoning should be assumed. You should urgently seek medical help.
While the doctor is on his way, you can help the victim yourself. First, you need to do everything possible to stop the process of absorption of the drug components into the blood. To do this, you need to remove it from the stomach as quickly as possible. Pre-medical measures include:
- Gastric lavage. The patient should be given 4-5 glasses of warm salted water to drink and induce vomiting. This procedure should be repeated until the discharged masses are cleared. Washing can be done if the patient has sufficient strength and is fully conscious. If the vomit is dark in color, you need to stop the process - this means that internal hemorrhage has occurred.
- After successful rinsing, it is necessary to “collect” the remaining toxins in the intestines and stomach. To do this, take sorbents - Activated carbon, Smecta or Enterosgel. Activated carbon is taken according to a person’s weight - 1 tablet of carbon per 10 kg of weight. For comfortable use, the tablets can be crushed into powder and washed down with plenty of water. Other products are taken as directed in the instructions or on the packaging.
- After the measures taken, the patient should be given alkaline mineral water in moderate quantities.
Video: Andipal drug for mildly reducing high blood pressure.
Video on the topic
How to take Andipal correctly? How quickly does this drug reduce blood pressure? Answers in the video:
Thus, different medications are sold in pharmacies to relieve pain, spasms and lower blood pressure. Many doctors prescribe combination drugs. Andipal is considered an effective and safe remedy. It works after just a quarter of an hour and relieves unpleasant symptoms for about six hours.
Fitolife® - innovation in the treatment of human hypertension
- Eliminates the causes of pressure disorders
- Normalizes blood pressure within 10 minutes after administration
To learn more…
