Cold and flu treatments Valenta Pharmaceuticals INGAVIRIN

Ingavirin is used as part of the treatment of respiratory system infections and is prescribed to reduce the risk of infection. This is an antiviral agent that exhibits activity against various pathogens of respiratory pathologies. The product cleanses the patient’s body of pathogenic microorganisms and speeds up recovery. Used in therapeutic and pediatric practice.

The effectiveness of the medicine has been proven in studies conducted by the manufacturer.

Ingavirin for children

The use of Ingavirin in pediatric practice, that is, for children, has not been studied at all in clinical studies.
This means that the effectiveness and safety of the drug for children has not been confirmed by any clinical studies, which were simply not conducted for obvious ethical reasons. This fact alone suggests that Ingavirin should not be used for children, since it is unknown what consequences this may have. In addition, you need to know that the history of Ingavirin is much longer than it seems at first glance, and there are very serious facts in it that indicate the need to abandon the routine use of this drug for children.

The fact is that the drug was registered and released onto the pharmaceutical market as an antiviral agent only in 2008, and synthesized back in the 70s of the 20th century. After the drug was obtained in the 70s, it was used as a stimulant of hematopoiesis in people receiving chemotherapy to treat malignant tumors. In principle, the drug is still used in oncological practice, but under a different name ( Dicarbamine

Thus, it is obvious that Ingavirin has an effect on the process of hematopoiesis, which can provoke negative consequences in children. After all, children's regulatory systems are not as perfect and stable as those of adults, as a result of which even minimal interference in their work can lead to negative consequences, including serious illnesses. It is precisely because of this potential danger that it is not recommended to use Ingavirin for the treatment of influenza and ARVI in children under 18 years of age. To treat children, it is better to use safer antiviral drugs, such as Arbidol, Anaferon, etc.

"Ingavirin": analogues

Cheaper than this drug you can find similar medicines based on the same active ingredient, in particular, Dicarbamine.

As everyone knows, many patients who prefer to save money, having barely received a prescription from a doctor, immediately look for analogues of recommended medications. Ingavirin is not a cheap medicine, so the search for an analogue is a completely understandable phenomenon.

There is no product on the market that can completely duplicate the properties of this drug. The only closest analogues of Ingavirin are Russian Dicarbamin and Vitaglutam.

However, the purpose of the first is slightly different. So, it is used in oncology, and the dosage of “Dicarbamine” for the treatment of viral diseases will be higher, in the end, in terms of finances, the result will be almost the same. However, if the form is not severe and this remedy helps you, you can try using an analogue of the drug Ingavirin. In general, it is better to choose a similar drug at a price that is more acceptable to you, not in terms of composition, but in terms of action; here the list will be more significant.

Pharmacological effect

Has an antiviral effect, effective against influenza viruses of types A (A/H1 N1, including “swine” A/H1 N1 swl, A/H3N2, A/H5N1), type B, adenovirus infection, parainfluenza, respiratory syncytial infection. The antiviral mechanism of action is associated with the suppression of virus reproduction at the nuclear phase, delaying the migration of newly synthesized NP virus from the cytoplasm to the nucleus.

According to the instructions for use of Ingavirin:

significantly shortens the period of temperature rise.

With ARVI, fever usually lasts 2–4 days, and with influenza up to 5 days. When treated with Ingavirin, the duration of this stage of the disease is reduced by 1–2 days;

- helps reduce intoxication.

Viruses release toxins that, when absorbed into the blood, cause headaches and weakness. Influenza viruses are more toxic than the pathogens of acute respiratory viral infections, so severe joint and muscle pain and dizziness are observed with influenza. Ingavirin reduces the intensity of these manifestations, which are practically not relieved by symptomatic means;

helps reduce catarrhal symptoms.

It cannot be said that taking Ingavirin will completely relieve a patient with influenza or ARVI from rhinorrhea or sneezing attacks. However, the intensity of catarrhal manifestations will still decrease. With the combined use of Ingavirin and symptomatic drugs, the effect will be even more pronounced;

helps reduce the duration of the disease.

Here it is appropriate to recall folklore again, which speaks of a week-long self-healing from influenza and ARVI. According to research data, Ingavirin significantly reduces the duration of influenza and ARVI by 1–3 days. Thus, you can get back on your feet in not seven, but six days. And, if the immune system is in perfect order, then you have every chance of going to work within four days after the onset of the disease;

helps reduce the number of complications.

As many people know, the main danger of influenza and ARVI lies not in the infection itself, but in its possible complications. The likelihood of additional bacterial infection is quite high in young children, the elderly, and patients with a reduced immune response. Note that the addition of a bacterial infection automatically means the subsequent use of antibiotics as first-line drugs.

The use of this drug reduces the likelihood of complications from viral infections.

Indications for use of Ingavirin

Prescribed as part of complex therapy for respiratory infections. A course of therapy helps reduce the duration of the disease and reduce the risk of complications. It is also used for preventive purposes before the cold season. Vitaglutam helps the body cope with common ARVI pathogens.

Main indications

An acute infection of the respiratory system caused by influenza virus type A or B. Infection usually occurs through airborne droplets, and the mucous membranes of the nasopharynx and throat become the entry point for infection. Symptoms of the disease include fever, weakness, runny nose, sneezing and cough.
Other respiratory system infections: adenovirus infection, parainfluenza, rhinovirus disease, respiratory syncytial virus infection.
Reducing the risk of infection during exposure to adverse factors and before the start of the cold season.

If serious symptoms appear, such as prolonged fever and difficulty breathing, you should undergo a medical examination. The specialist will prescribe an effective treatment regimen.

Classic treatment of influenza and ARVI includes Ingavirin

If you treat ARVI, you will recover in seven days, but if left to its own devices, the disease will go away in a week. Who among us does not remember this statement? Many patients seriously think about the question: is it worth taking Ingavirin and other antiviral drugs for the treatment of influenza and ARVI or not? Let's try to understand this dilemma.

In the CIS countries, standard protocols for the treatment of influenza and ARVI offer a combined regimen, which includes:

- antiviral drug.

Among the frequently recommended drugs, we note Arbidol, Kagocel, Ingavirin, Amiksin, Amizon or others.

For severe cases of influenza, especially in immunocompetent patients (for example, HIV-infected people, the elderly), Tamiflu or Relenza are prescribed. Let us repeat: these are the drugs that have proven high effectiveness against the influenza virus.

- symptomatic remedies.

These medications are selected individually based on clinical manifestations. So, for elevated temperatures, antipyretics are prescribed, for coughs - mucolytics or antitussives, for a runny nose - decongestants that reduce swelling of the nasal mucosa, and so on.

Often, diligent therapists supplement the treatment regimen for viral infections with homeopathic medicines - Aflubin, Anaferon, Oscillococcinum and others. After such appointments, the patient comes to the pharmacy with a hefty prescription, sometimes including 6-7 drugs.

And now I would like to draw an analogy with foreign countries. What do they take for influenza and ARVI? It turns out that in developed countries, catarrhal infections are much easier to treat. Symptomatically.

You may ask, how to treat viruses, how to fight them? The answer is very prosaic: no way. In any generally healthy person, the respiratory or influenza virus clears on its own within about seven days. That is, the same week.

However, with a decrease in immunity, the disease can be delayed and complicated by bacterial infection. That is why most of our doctors trust domestic treatment regimens for influenza and ARVI more. And they continue to prescribe antiviral drugs as first-line drugs.

Indications and principle of action

Studies have shown the effectiveness of the drug against infection:

Causative agents of influenza of different strains and parainfluenza;
Respiratory syncytial infectious agents;
Adenoviruses;
Enteroviruses;
Rhinoviruses;
Coxsackie viruses.

Coxsackie virus

Taking a pharmaceutical drug helps remove pathogens of viral diseases from the body of a sick baby, reduces the duration of illness and reduces the risk of complications.

Vitaglutam as part of a pharmaceutical product has three main effects:

Prevents the proliferation of infectious agents, which leads to suppression of the development of the disease, helps the immune system quickly overcome the infection.
Tones up the immune system. If the defense is weakened, the infection may develop again. The active substance of the drug has an enhancing effect on the body's hidden reserves, helps to increase the concentration of interferon in the blood and improves resistance to infection by ARVI viruses.
Inhibits inflammatory processes, prevents infection from spreading, which leads to rapid recovery.

After taking Ingavirin, the number of white blood cells responsible for eliminating viral particles increases, and the anti-inflammatory effect of the pharmaceutical drug is associated with blocking the cytokines that cause this process.

The sooner they start giving the drug to a child, the sooner their health will improve.

The first signs for taking antiviral medication:

Snot of mucous consistency;
Temperature rise;
Nausea and diarrhea;
Dry throat, cough;
Pain in the head and muscles.

Ingavirin is taken only for illnesses of a viral nature. If the infection is caused by bacteria or has become attached, antibiotics will be required. The harmful effects of microorganisms can be detected by the appearance of plaque on the tonsils or thickening and greening of nasal discharge.

Analogues of Ingavirin 90 mg

Which is better: Ingavirin or Arbidol?

Scientists conducted a study, the purpose of which was to compare the safety and effectiveness of Ingavirin compared to Arbidol. In patients taking Ingavirin, body temperature dropped faster, a decrease in symptoms of intoxication was noticed, and not a single case of complications was observed. Neither the patients taking Ingavirin nor the patients taking Arbidol had any side effects.

Which is better: Ingavirin or Amiksin?

These funds have a number of significant differences. For example, Amiksin is allowed to be taken from 7 years of age, while Ingavirin is only allowed from 18. Ingavirin is not compatible with any antiviral agents, while Amiksin can be taken with antibiotics and other medications. Ingavirin is prescribed for influenza and other types of acute respiratory viral infections, while Amiksin has a broader focus. Moreover, both drugs have very low toxicity. Thus, Ingavirin as a medicine for influenza for adults is more effective, and in case of illness with herpes, hepatitis, etc., Amiksin is recommended.

Which is better: Ingavirin or Kagocel?

Kagocel is also a children's drug; it can be taken by children from 3 years of age; in addition to influenza, this remedy is also used against herpes. It can also be used simultaneously with other medications and antibiotics. This drug is non-toxic and does not accumulate in the body.

Which is better: Lavomax or Ingaverin?

Lavomax, like Ingaverin, is used from the age of 18, but has a wider spectrum of action. This product is also compatible with antibiotics. Lavomax has a wider range of contraindications, since it contains lactose.

Is Ingavirin an antibiotic?

Many people, when prescribing Ingavirin, are interested in whether this drug is an antibiotic or not. The answer is negative: it only affects viruses and does not affect human immunity in any way. Sometimes doctors recommend taking the drug along with antibiotics, but this is allowed only if the condition worsens due to colds.

If there are no associated problems, then only Ingavirin is prescribed. Analogues of the drug also do not belong to the category of antibiotics. However, before purchasing them, you should study the annotation about what effect they have.

Analogs

If the patient is allergic to the drug or falls into the group of restrictions on its use, then analogues should be used.

List of analogues:

Amizon;
Ergoferon;
Hyporamine;
Arbidol;
Oksolin;
Kagocel.

The drug Ingavirin is widely used in the treatment of influenza, acute respiratory viral infections, viral tonsillitis, and inflammatory diseases of the ENT organs provoked by a variety of viral agents. The drug is produced in capsule form with different dosages. It must be administered orally.

The only condition for safe use is use exclusively within the expiration date established by the manufacturer on the packaging. The medicine does not cause a negative response in people who are not allergic to it. If you follow the rules for taking an overdose, there can be no overdose. The drug does not require a doctor's prescription. You can buy it at the pharmacy. There are a significant number of analogues on sale.

pharmachologic effect

The drug is effective for the treatment of colds and flu caused by influenza viruses of strains A (H1N1, including “swine”, H1N1 sw1, H3N2, H5N1), and B. Also, the drug is able to quickly and effectively resist viral agents.

The active substance of the drug has a modulating effect on the processes of functional activity of interferons. This leads to an increase in the concentration of interferons in the blood to physiological norms. The medicine enhances and leads to normal levels of reduced α-interferon and γ-interferon. This means that at the site of inflammation, the concentration of leukocytes increases significantly. This mechanism allows you to speed up the healing process, the patient’s condition quickly improves.

Therapeutic effect of Ingavirin in case of infection with influenza and ARVI viruses:

reduction of manifestations of intoxication syndrome (headaches and muscle pains, body aches, weakness, apathy, drowsiness);
reduction of inflammatory manifestations (reduction of swelling and redness of the tissues of the ENT organs);
reducing the risk of developing possible complications or consequences;
acceleration of the overall recovery period.

When studying toxicity, it was found that the drug has a weak toxic effect. Doctors classify it as a safe pharmaceutical. The medicine has no mutagenic, immunotoxic, allergenic, or carcinogenic effects on the body, and does not act as a local irritant.

The drug is recognized as an effective antiviral agent that does not affect the genitals and sexual function. No negative embryotoxic effects were detected. The drug does not enter into the body's metabolic processes.

At the recommended dosage, the drug is completely eliminated from the blood plasma; the components of the drug do not accumulate in the human body. During the experiments, scientists found that the drug quickly enters the bloodstream from the organs of the digestive system and reaches the organs in the same proportion. The maximum concentration of the drug in the bloodstream, plasma and organs is achieved half an hour after oral administration of the drug.

The components of the drug are released into the external environment 24 hours after use. During this period, the body leaves approximately 80% of the substance taken: 35% leaves the body in the period from 5 to 30 minutes, the next 45% after 24 hours. The remaining substance is removed from the body over the next 48 hours.

Instructions for use

How to take Ingavirin

Ingavirin capsules should be taken orally, swallowed whole, without biting, chewing, cutting or pouring out its contents, but with a small amount of water (half a glass is enough). Capsules are taken regardless of food intake, that is, Ingavirin can be taken at any time convenient for the person.

For the treatment of influenza and acute respiratory viral infections (acute respiratory viral infections), Ingavirin should be taken 90 mg (1 capsule of 90 mg or 3 capsules of 30 mg) once a day for 5 to 7 days, depending on the severity of the disease. It is necessary to start taking Ingavirin from the moment the first signs of influenza or ARVI appear. However, if for some reason it is impossible to start taking Ingavirin immediately after the onset of symptoms of the disease, then it is optimal to do this within the next 36 hours. If more than 36 hours have passed since the first signs of the disease appeared, then you can start taking Ingavirin, but its effectiveness will be much lower.

To prevent influenza and ARVI during mass epidemics or after contact with already sick people, Ingavirin should be taken 90 mg (1 capsule of 90 mg or 3 capsules of 30 mg) once a day for a week.

special instructions

Ingavirin is not recommended to be taken in combination with other antiviral drugs, as this may lead to excessive stimulation of the immune system with the subsequent development of autoimmune diseases.

According to experimental studies on animals, it was found that Ingavirin has very low toxicity, since the lethal dosage exceeds the therapeutic dosage by more than 3000 times. Thus, even when taking high dosages of Ingavirin, the risk of severe complications resulting in death is very low.

Impact on the ability to operate machinery

Ingavirin does not affect the functioning of the central nervous system and does not have a sedative effect, therefore, while using the drug, you can engage in any type of activity, including those related to the need to have a high reaction speed and concentration.

Overdose

Cases of overdose with Ingavirin have never been recorded during the entire period of observation of the clinical use of the drug.

Interaction with other drugs

Ingavirin has not been shown to interact with any medications. Therefore, Ingavirin can be taken in combination with any other medications, with the exception of antiviral drugs.

How to drink Ingavirin: dosage of the drug

Before taking Ingavirin, you should consult your doctor and exclude all possible contraindications to taking this medication. It is prescribed for both prevention and active treatment.

From a preventive point of view, effectiveness is observed when starting administration even after direct contact with an infected person. But it is recommended to start prevention approximately 10 days before the outbreak of a seasonal epidemic of colds and flu.

For therapeutic purposes, it is necessary to begin therapy immediately after the appearance of relevant clinical symptoms. The sooner therapy is started, the higher the chances of a speedy recovery. Although it is possible to take the drug 2-3 days after the onset of the disease.

In the table below, the dosage of Ingavirin is calculated for an adult with a body weight of at least 60 kg. If there are deviations from this parameter, then you should discuss with your doctor a decrease or increase in the daily dosage, since it is the concentration of the active substance in the blood plasma that has a significant impact on the speed of the recovery process.

Ingavirin dosage for adults
Common types of flu	90 mg 1 time per day for 7 days
ARVI, acute respiratory infections and other colds	60 mg (2 capsules of 30 mg each) 1 time per day for 5 days
Preventative treatment	90 mg in the morning daily for 7 days

Pharmadynamics

Antiviral drug.

Preclinical and clinical studies have shown the effectiveness of the drug Ingavirin against influenza viruses type A (A(H1N1), including swine A(H1N1)pdm09, A(H3N2), A(H5N1) and type B, adenovirus, parainfluenza virus , respiratory syncytial virus; in preclinical studies: coronavirus, metapneumovirus, enteroviruses, including Coxsackie virus and rhinovirus.

The drug Ingavirin promotes accelerated elimination of viruses, reduces the duration of the disease, and reduces the risk of complications.

The mechanism of action is realized at the level of infected cells due to the stimulation of innate immune factors suppressed by viral proteins. In experimental studies, in particular, it was shown that the drug Ingavirin increases the expression of the first type interferon receptor IFNAR on the surface of epithelial and immunocompetent cells. An increase in the density of interferon receptors leads to an increase in the sensitivity of cells to endogenous interferon signals. The process is accompanied by activation (phosphorylation) of the STAT1 transmitter protein, which transmits a signal to the cell nucleus to induce antiviral genes. It has been shown that under conditions of infection, the drug stimulates the production of the antiviral effector protein MxA, which inhibits the intracellular transport of ribonucleoproteins of various viruses, slowing down the process of viral replication.

The drug Ingavirin causes an increase in the level of interferon in the blood to the physiological norm, stimulates and normalizes the reduced α-interferon-producing ability of blood leukocytes, and stimulates the γ-interferon-producing ability of leukocytes. Causes the generation of cytotoxic lymphocytes and increases the content of NK-T cells, which have high killer activity against virus-infected cells.

The anti-inflammatory effect is due to the suppression of the production of key pro-inflammatory cytokines (TNF-α), IL (IL-1β and IL-6), and a decrease in the activity of myeloperoxidase.

Experimental studies have shown that the combined use of the drug Ingavirin with antibiotics increases the effectiveness of therapy in a model of bacterial sepsis, incl. caused by penicillin-resistant strains of staphylococcus.

Experimental toxicological studies conducted indicate a low level of toxicity and a high safety profile of the drug.

According to the parameters of acute toxicity, the drug Ingavirin belongs to the 4th toxicity class - “Low toxic substances” (when determining LD50 in acute toxicity experiments, lethal doses of the drug could not be determined).

The drug does not have mutagenic, immunotoxic, allergenic or carcinogenic properties, and does not have a local irritant effect. The drug Ingavirin does not affect reproductive function and does not have embryotoxic or teratogenic effects.

Therapeutic effect

The active substance helps the patient's body fight infectious agents by activating the innate immune system and improving the protective properties of tissues. The effectiveness of the chemical compound in the fight against adenovirus, respiratory syncytial virus, pathogens of parainfluenza and influenza A, B has been proven. A course of use is needed to remove infectious agents from the body and restore the functioning of the immune system. Use as a prophylactic agent helps to significantly reduce the risk of infection.

Additional properties

Improving the production of type 1 interferons. These natural components of the immune system prevent viral particles from spreading in the body.
Increased number of interferon receptors on cell membranes. This property enhances the effects of internal interferon and stimulates the immune system.
Activation of intracellular mechanisms to combat the viral threat. The genetic regions responsible for the synthesis of antiviral proteins are launched. Cellular transport is also disrupted, which slows down the process of creating new viral particles.
Activation of cellular and humoral defense mechanisms. Vitaglutam stimulates the production of endogenous interferon by leukocytes and improves the functioning of leukocytes that can destroy infected cells.
Reducing the severity of the inflammatory process. The drug blocks the production of inflammatory mediators in tissues, thereby relieving cold symptoms.
Improved prognosis when combined with antimicrobial agents. Helps fight bacterial threats.
Reducing the duration of symptoms of ARVI and reducing the risk of complications.

The medicine is considered safe and low-toxic.

Adverse reactions

Medicines that have a systemic therapeutic effect can cause unpleasant symptoms. Getting the product into the body of some people leads to the development of an allergic reaction. This condition is due to the sensitivity of the immune system to the substances contained in the capsule. Typical signs of allergies include redness of the skin, skin rashes and itching. More serious manifestations are possible.

Consult a doctor before use

Before using the product, you need to read the instructions and clarify the composition. The patient should not have intolerance to the components of the capsules. If signs of immunological reactions appear during therapy, you need to make an appointment with a doctor.

Ingavirin price, where to buy

The average cost of Ingaverin in Ukraine is approximately 130-160 UAH. In Moscow and Russia, the price for Ingavirin 90 mg varies from 390 to 482 rubles per pack.

You can buy Ingavirin in Moscow and find out how much it costs at any pharmacy in the city.

The average price for antiviral drugs is 20-50 UAH.

What types of viruses is it effective against? Does it make sense to take it for colds and acute respiratory viral infections?

Ingavirin is an antiviral and anti-inflammatory drug. It is effective in the treatment of influenza viruses belonging to types A and B. The active ingredients included in Ingavirin block the reproduction of viruses, normalize a person’s own immunity, and stimulate the formation of cells that destroy viruses.

I learned about this medicine when I myself had a severe cold, and it was not possible to go on sick leave. Friends recommended this drug. I didn’t regret it - I really managed to cope with the disease quite quickly. From further practice of using the drug, I concluded that ingavirin is especially effective if you start taking it at the first sign of a cold or flu. Then everything flows much easier. It is possible, of course, that this does not happen for everyone - the individual characteristics of the body are different for everyone, but I like this drug, I always keep it in my home medicine cabinet as “heavy artillery” for fighting colds.

Antiviral "Ingavirin": tablet composition and action

Antiviral "Ingavirin" is a patented and clinically tested drug that can interrupt the process of duplicating the RNA of the virus and its subsequent introduction into a living cell of the human body.

Ingavirin contains vitaglutam, a derivative of imidazolylethanamide pentanedioic acid, which is the basis for the production of diacarbamin. The remaining components are excipients that protect the drug from the negative effects of environmental factors. In particular, the drug is available in the form of gelatin capsules with an enteric coating. This reliably protects the internal contents from transformation under the influence of the acidic contents of the stomach.

The main pharmacological action of Ingavirin is aimed at interrupting the process of replication (reproduction) of viruses belonging to groups A and B. These are all serotypes: swine, avian, seasonal (A/H1N1, A/H3N2 and A/H5N1). A negative effect of the drug on the causative agent of adenoviral and respiratory syncytial infections was revealed.

After assimilation through the bloodstream, it is transported to the localization sites of the infectious agent and, by suppressing the synthesis of nuclear transformation, stops the production of new RNA of the viral microflora. Penetration of the microorganism from the cytoplasm into the cell nucleus becomes impossible, and gradual elimination of pathogenic microflora occurs. The patient feels a significant improvement in his condition and recovers, all damaged mucous tissues are restored.

The second phase of the antiviral action begins after the active substance penetrates the bone marrow cells. Here, the production of special forms of leukocytes is enhanced, capable of actively finding and neutralizing various forms of viruses, the so-called NK-T cells, characterized by aggressiveness towards cells with an altered genetic structure. And here it’s worth making a small digression.

It is necessary to understand that the virus does not have its own cellular structure. For subsequent reproduction, it needs to insert its RNA genetic code into the cells of the “host” or infected person. Such cellular structures have a genetic code different from that programmed by human DNA. And it is precisely because of this distinctive characteristic that T-leukocytes can identify and inactivate viruses in the human body.

Another effect of this drug is to stimulate the production of human interferons. These specific substances are a natural cure for many infections, since they are active antigens whose action is aimed at destroying pathogenic microflora. It is also worth noting the anti-inflammatory effect, which manifests itself in reducing swelling of the mucous membranes, reducing elevated body temperature, and eliminating pain in large muscles.

Ingavirin price

The difference in cost between Ingavirin and its analogues can be quite significant. This can be explained very simply: each manufacturer regulates the price at its own discretion. For example, during flu epidemics, pharmaceutical companies increase the cost of drugs. Many people, having only noticed the first symptoms of a cold, rush to buy pills, not paying attention to senseless overpayments, although this can be avoided. The table below will help you understand the cost of antiviral drugs that can be used to treat colds and respiratory infections:

Name of the drug	Manufacturer country
Kagocel	Russia	240
Ribavirin	Cuba	160
Cycloferon	Russia	165
Remantadine	Russia	250
Hyporamine	Russia	150

The principle of action of ingavirin

Ingavirin for children is a fairly effective remedy for treating colds and flu. Recent clinical studies have proven the high capabilities of this pharmaceutical product, used to reduce the likelihood of human infection with viral infections, including influenza (especially its dangerous types A and B). This drug actively fights other viruses, including parainfluenza, rhinovirus, adenovirus, and respiratory syncytial infections.

The use of the drug, which has an immunomodulatory effect on the body, removes the most dangerous pathogens from the body, shortens the period of the disease, and reduces the risks of developing possible complications. Timely initiation of therapy can reduce the likelihood of contracting a viral infection.

The main active ingredient of Ingavirin is vitaglutam, which has the ability to stimulate the activity of cells affected by the virus. It is this substance that acts as the main stimulator of immune defense, which is suppressed during the penetration of viruses into the human body.

Correct and timely use of Ingavirin capsules in children and adults produces the following effects on the human body:

increases the number of receptors that perceive interferon; thanks to this quality, infected cells increase their own sensitivity to this factor, which causes a rapid reaction in the form of an immune response;
has an effect on proteins, they are the main signaling agents for the activation of antiviral genes;
Ingavirin affects the process of movement of ribonucleoproteins occurring inside the virus cells, which contributes to a strong inhibition of the pathogen’s reproduction procedure;
increases the level of interferons in the human body to the physiological norm, this becomes possible by influencing leukocytes, their restoration and increasing their ability to create immune factors;
increases the number of white blood cells, which are vital for organizing the work of destroying viral activity;
suppresses cytocoins, substances that provoke the development of inflammatory processes.

Instructions

Take the medicine orally with clean water. You can take the capsule regardless of food, but it is advisable to drink Ingavirin at the same time of day

A child's immune system is not as developed as an adult's, so it is important to start treatment on time

Ingavirin 90 should be used according to the following scheme:

For therapeutic purposes, children 7-17 years old are prescribed one Ingavirin 60 capsule per day (60 mg);
Adults, for therapeutic purposes, are prescribed 90 mg per day;
For prevention purposes, adults, immediately after contact with a suspected infected person, take 1 capsule every day for a week.

Begin treatment immediately after symptoms appear (cough, fever, runny nose), preferably no later than two days from the moment of infection. Depending on the severity of the infection, continue therapy for 5-7 days.

Interesting read: neurotic cough in children

Analogues of the drug

Despite the fact that Ingavirin is considered one of the effective antiviral drugs, it should not be taken by children under 7 years of age, and the cost of the drug is not the most affordable (about 450 rubles). Before considering analogue medications, it is worth noting that pharmacies sell medications with similar effects, but there are no complete analogues of Ingavirin.

Kagocel

An antiviral drug that can be given to children from 3 years of age. Effectively fights infections caused by viruses and helps strengthen the immune system. One package contains 10 tablets, which are taken three times a day. The course of treatment is from 4 days.

Price: from 250 rubles.

Ergoferon

Ergoferon has antiviral, immunomodulatory and anti-allergenic properties. It is allowed to be taken by babies from 6 months for the purpose of preventing and treating viral diseases. The package contains 20 lozenges. For children from six months to 3 years old, it is recommended to dissolve 1 tablet in a small amount of boiled water and use 3 times a day.

Price: from 300 rubles.

Cycloferon

The analogue drug fights viral infections, eliminates inflammation and strengthens the body's defenses. Cycloferon can be given to children from 4 years of age. The package contains 20 tablets, each of which contains 150 mg of active substance. Take from 1 to 4 tablets (depending on age) at a time half an hour before meals.

Price: from 300 rubles.

Anaferon for children

Anaferon has an immunomodulatory and antiviral effect and is indicated in the complex treatment of infections. Can be given to babies from the first month of life. On the first day you need to take 8 tablets, then 1 tablet 3 times a day.

Price: from 200 rubles for 20 tablets.

Arbidol

Arbidol is taken for influenza and respiratory diseases. The medicine is available in tablets, capsules and powder. Can be used by children from 3 years of age. Tablets are sold in dosages of 50 and 100 mg. The course of treatment is from 5 to 14 days depending on the type of infection.

Price: from 150 (10 pieces of 50 mg) to 450 (20 pieces of 100 mg).

To treat children with Ingavirin, you need to choose the correct dosage - 60 mg. The medicine must be taken once a day, regardless of meals, which is very convenient. Despite the fact that the price is higher than that of other analogues, one package of the drug is enough for the full course of treatment. Ingavirin ensures rapid recovery and protects the body from recurrent diseases.

Ingavirin 90 mg and 60 mg, what is the difference

The pharmaceutical product is produced in capsules, equipped with a blue color and a white logo. Inside the tablets there are granular elements and white powder. The product differs in the dosage of pentanedioic acid. That is, when considering the question of Ingavirin, 90 mg and 60 mg, what is the difference, it is worth noting that it lies in the content of the main component. In addition, both types of tablets contain additional components such as lactose, starch, and magnesium. Tablets for adults and children fight viral infections and inflammatory processes. The adult drug involves a higher content of the main substance, which is 90 mg. Also on sale is Ingavirin for children, it contains a minimum of acid, that is, the main substance in the amount of 60 mg.

The product requires research into its action and effectiveness. Based on the data that were obtained, it turned out that there is an effect on the fetus during pregnancy, but it is minimal. The same applies to the lactation period. If changes are observed during the use of the composition, it is worth stopping the treatment process. Allergic reactions can be identified as serious consequences, but they occur rarely. The drug does not have a sedative effect and has no effect on psychomotor reaction speed indicators, therefore it can be used by representatives of all professions. There are restrictions and contraindications in terms of using this composition in conjunction with other medications.

Operating principle

Ingavirin is a group of antiviral drugs.

Taking Ingavirin not only helps to remove these types of pathogens from the body of a sick child, but also shortens the duration of the infection and reduces the risk of complications of the disease. The action of vitaglutam is primarily based on stimulation of affected cells. In particular, this substance stimulates immune factors that are suppressed by viruses during an infectious disease.

As a result of taking the capsules, the number of interferon receptors increases, which increases the sensitivity of infected cells to this factor of the immune response. In addition, the drug affects proteins that give cells signals to activate antiviral genes. And thanks to the drug’s influence on the movement of ribonucleoproteins inside viral cells, the reproduction of the pathogen slows down.

The level of interferon during treatment with Ingavirin increases to normal, since the medication affects leukocytes and restores their ability to produce immune factors. It is also noted that taking the capsules increases the number of white blood cells responsible for destroying viral particles, and the anti-inflammatory effect of the drug is associated with suppressing the production of substances called cytokines.

For information on the specifics of using antiviral drugs, see Dr. Komarovsky’s program.

Composition and analogues

Many doctors strongly advise patients to take the drug Ingavirin. Feedback from experts indicates that in the presence of this medication, the patient’s body becomes more viable, synthesizes a sufficient number of protective factors and can resist viral infection. What makes this medicine so effective? It is based on a complex chemical compound called “vitaglutam”. It has a beneficial effect on the activity of the circulatory system. The same substance is contained in the drug “Dicarbamin”, which is used to fight cancer and to protect the blood during chemotherapy. What could a cure for cancer and a cure for the flu have in common? It turns out that there is nothing surprising in this fact. The fact is that the dosages of vitaglutam in medications are not the same, and the fact that different amounts of medication taken can have different effects on the body is no secret. Another drug with a similar mechanism of action on the body is Vitaglutam. It is proposed to be used to improve the process of hematopoiesis (that is, to accelerate the formation and maturation of blood cells). Thus, the substance from which the medicine “Ingavirin” is made has been used in medicine for a long time and has been successfully used. Analogues of this drug (according to the method of action) are the drugs “Dicarbamin” and “Vitaglutam”. However, these medications are powerless against viruses.

Absorption and excretion

Taking capsules in therapeutic doses is not accompanied by the detection of vitaglutam in the blood plasma. The substances quickly enter the bloodstream from the intestines and are distributed to internal organs, including the kidneys, liver and spleen. Course use of the drug leads to a gradual accumulation of substances in anatomical structures. The highest concentration of vitaglutam occurs approximately 60 minutes after administration. The chemical structure of the drug does not change in the liver.

The chemical compound is excreted from the body by the digestive tract and kidneys.

What is better than Ingavirin

In medical practice there is no concept of “best”, since today it is impossible to create a medicine that would be perfect for all people and at the same time be very effective. Therefore, instead of the concept “best,” the term “optimal” is used. By optimal, doctors mean the drug that best suits this particular person at the current moment in time. And it is precisely this optimal drug that will be the best for a particular person at the current moment in time.

Thus, for some there are no drugs better than Ingavirin, but for other people other antiviral agents, such as Kagocel, Arbidol, etc., are much better. Therefore, there is only one way to understand what is better than Ingavirin for a given person - by trying different drugs and choosing the optimal one for yourself.

Pharmacological characteristics

What is the medicine "Ingavirin"? Is this medicine for children or not? You will find answers to these questions in the materials of this article.

According to the instructions, the drug in question is antiviral. It has a detrimental effect on influenza viruses type B and A, as well as parainfluenza, adenovirus and respiratory syncytial infections.

What is the antiviral principle of action of the drug “Ingavirin”? The children's drug and medications for adults are able to suppress viral reproduction at the nuclear phase. This effect is due to the delay in migration of the synthesized NP virus from the cytoplasm to the nucleus.

The agent in question is capable of modulating the activity of the interferon system, as a result of which its content in the blood increases to a physiological level. Also, this medication normalizes and stimulates the reduced alpha and gamma interferon-producing abilities of blood leukocytes.

It should also be noted that the drug “Ingavirin” (60 mg) is capable of causing the generation of cytotoxic lymphocytes and increasing the content of NK-T cells, which have high killer and antiviral activity against cells transformed by viruses.

As for the anti-inflammatory effect of the drug in question, it is due to the ability of the drug to suppress the production of key pro-inflammatory cytokines such as IL-1β, TNFα and IL-6, as well as reduce the activity of myeloperoxidase.

Ingavirin instructions for use of the tablet for adults

The composition in question is a substance that has a modulating effect on the functional indicator of interferon activity. The drug ensures an increase in the amount of interferon contained in the blood to the physiological norm. Also, its property is to stimulate and normalize the reduced ability of leukocytes. The anti-inflammatory effect is due to the ability to suppress the production of harmful elements. The effectiveness of the therapy lies in the fact that the period of a febrile state is significantly shortened, the process of intoxication is reduced, as is the duration of the disease.

Information about the drug Ingavirin, instructions for use, price, reviews, analogues are provided for informational purposes. Before considering the detailed properties of Ingavirin, instructions for use, tablets for adults, you need to familiarize yourself with the list of actions of the composition.

Therapy for influenza of several groups, as well as for acute respiratory viral infections;
use for the prevention of influenza in adult patients;
treatment of influenza forms A, B in young patients under 17 years of age.

Thus, the drug performed well in the case of therapeutic and preventive measures for numerous conditions. It is indicated for use during the detection of the first signs of pathology and is designed to combat various phenomena of any etymology. Ingavirin 90 mg and 60 mg is not used in cases of lactose deficiency, pregnancy and breastfeeding. It is prohibited to use the drug in childhood and adolescence. If there is a high level of sensitivity to the composition, you should abstain.

When considering Ingavirin, instructions for use, price, reviews, analogues, it is worth paying attention to several points. The product is used internally, the scheme does not depend on food preferences and habits

For the treatment of respiratory infections, 90 mg is prescribed once a day for adults. Persons 13-17 years old should use 60 mg once a day. The duration of the therapeutic effect is up to a week, based on the severity of the pathological process. It is best to start using the composition in the initial stages of the pathology, as soon as the first signs appear. For preventive purposes, the dosage regimen is the same.

Analogues of Ingavirin, list of drugs

tilaxin;
Panavir;
Lavomax;
Tamiflu;
tilorone;
kagocel;
hyporamin;
ribavirin;
arbidol;
imunoflazid;
imustat;
cycloferon;
oxolin;
ergoferon;
anaferon;
arbivir;
amizon;
remantadine.

Promptly prevent ARVI with antiviral drugs. According to doctors' reviews of Ingavirin 90, the later treatment with an antiviral drug was started, the less effective it was. Important - instructions for use of Ingavirin, price and reviews do not apply to analogues and cannot be used as a guide to the use of drugs of similar composition or action. All therapeutic prescriptions must be made by a doctor. When replacing Ingavirin with an analogue, it is important to consult a specialist; you may need to change the course of therapy, dosages, etc.

Don't self-medicate!

Therapy results

What does Ingavirin help with? What effect does the medicine have if taken according to the recommendations given by the doctor?

When carrying out drug antiviral therapy, positive dynamics in the course of the disease can be achieved:

Reduces the acute period of the disease by 2 times. Without the use of an antiviral drug, a cold can progress over the course of a week. If you take an immunomodulator, you can recover within 3 days.
Smooth restoration of body temperature. Within 24 hours, lytic normalization of all indicators occurs.
Elimination of symptoms caused by intoxication of the body. The chills quickly disappear, sweating normalizes, and muscle pain and headaches go away.
Catarrhal symptoms are reduced. The patient ceases to suffer from nasal congestion, runny nose, cough, sneezing and pain in the throat.
The likelihood of developing complications is excluded. The immunomodulator prevents the attachment of bacterial microflora and eliminates the possibility of suppuration.

The active substance on which the drug is developed accumulates in the body - in physiological fluids and soft tissues. This provides a preventive effect for 3 weeks after the therapy is completed. Such properties of the drug eliminate the possibility of re-infection.

What are Ingavirin tablets for colds, sore throat and flu?

In the question of why Ingavirin tablets help with colds, flu and sore throats, one inaccuracy has crept in, which can be confusing when visiting the nearest pharmacy. The fact is that the dosage form of this antiviral drug is capsules. It is not available in tablet form.

But let’s return to the essence of the question posed, because indeed, practicing doctors have increasingly recently prescribed this drug as part of complex therapy for various diseases of the upper respiratory tract.

It’s worth starting with the fact that there are absolutely clear indications for its use, these are:

ARVI and acute respiratory infections caused by microorganisms of viral etiology;
influenza of various types;
adenovirus and respiratory syncytial infection (especially in immunocompromised individuals);
prevention of seasonal colds.

For a bacterial infection, it is prescribed only if there is confidence in the presence of combined forms of pathogens, including viruses that are sensitive to the active substance of the pharmacological agent.

"Ingavirin" for sore throat can be prescribed either as an immunostimulant, or if there are laboratory data indicating that the disease is caused by a sensitive group of herpes viruses (the so-called catarrhal or herpetic sore throat, which has recently become widespread in the general population).

Ingavirin, taken in accordance with the doctor’s recommendations for colds and flu, allows you to achieve positive dynamics in the course of the disease:

the duration of the acute period is reduced by approximately 1.5-2 times (if a cold lasts approximately 7 days without taking an antiviral drug, then with such therapy, performance returns after 3 days);
elevated body temperature normalizes lytically (smoothly) within 24 hours from the start of treatment;
symptoms of general intoxication are quickly eliminated (headache and muscle pain, chills, dizziness, increased sweating go away);
catarrhal symptoms (nasal congestion, sore throat, runny nose, sneezing and cough) are significantly reduced;
the addition of secondary bacterial microflora and the subsequent development of purulent complications is practically not diagnosed.

The active substance can accumulate in the physiognomic fluids of the body and some tissues, as a result of which the preventive effect lasts approximately 3 weeks after the end of the course of administration. This eliminates the risk of re-infection after recovery.

Effect of taking

The drug belongs to the antiviral group according to its pharmacological group. It is capable of destroying viruses that cause influenza and other acute respiratory diseases. The effect is based on suppressing the reproduction of pathogenic organisms even at the nuclear phase. Ingravirin has multiple effects. The instructions for use say that the medicine:

Reduces the time of fever and body aches. Reviews from doctors and patients confirm that the number of days of fever is significantly reduced. If during acute respiratory viral infections and influenza the temperature lasts up to 5 days, then after taking it - about 2 days.
Reduces intoxication of the body. As viruses multiply, they release toxins, causing a person to experience headaches and muscle discomfort. If the influenza virus attacks, then the patient’s health is very poor. He experiences joint pain, dizziness and pain in the eyes. Such conditions can be treated with Ingavirin. The instructions for use indicate that intoxication of the body is significantly reduced, which cannot be achieved by taking conventional medications that are aimed at relieving the symptoms of the disease.
Reduces catarrhal manifestations of the disease. Of course, the drug does not completely relieve the patient of a runny nose and sneezing. But in combination with symptomatic therapy, this condition goes away faster.
Reduces the overall duration of the disease. It is known that ARVI can go away on its own in 5 days. However, with the flu, the disease often drags on. Taking it can speed up recovery and the patient recovers at a faster pace.
Reduces the risk of complications. Doctors know that it is not the infection itself that is dangerous for the patient. Complications after it are more terrible. People with reduced immunity, the elderly and children are susceptible to bacterial infection. As a result, patients have to take antibiotics, which increases the burden on the weakened body. Ingavirin can reduce the likelihood of complications. The instructions for use by adults contain clear instructions for this, confirmed by clinical studies.

In addition to antiviral activity, the drug has an anti-inflammatory effect. This possibility is due to the activation of the production of the corresponding components.

Indications

It has been proven that Ingavirin is able to increase interferon levels to physiological norms. It increases the productivity of special leukocytes in the blood. They are the ones who absorb the body cells affected by the virus. Plus, they have a direct antiviral effect.

Ingavirin tablets reduce the synthesis of molecules involved in the body's inflammatory reactions. Below in the article we will answer the main question: what does the medicine help with? What is included in the indications for use?

The mechanism of action of the drug is aimed at promptly suppressing the reproduction of the virus and blocking its further development. Ingavirin has a high-quality antiviral and anti-inflammatory effect. It is absolutely safe for humans during use and does not cause any complications afterwards.

Ingavirin is taken in the treatment of:

various ARVI viruses;
influenza A and B;
as a prevention of infectious diseases;
respiratory syncytial infection;
for the treatment of respiratory viral diseases in children under 7 years of age (Ingavirin 30) and from 7 to 17 years of age (Ingavirin 60).

Ingavirin is approved for the prevention of colds and acute respiratory viral diseases. Combining Ingavirin and alcohol is not recommended.

Ingavirin quickly enters the blood. 30 minutes after administration, the patient experiences a maximum concentration of the active substance in the blood. It is excreted in the same form and is not metabolized. The intestines remove the largest part from the body in the first 24 hours, and the remaining part of the drug through the kidneys.

Contraindications for use

Among the contraindications to the use of Ingavirin it is worth noting:

- individual intolerance to the active substance or components of the drug.

As a rule, individual reactions are recorded in patients prone to allergies;

- lactose intolerance.

We have already mentioned that Ingavirin contains milk sugar - lactose. Therefore, for patients suffering from lactose intolerance, vitaglutam is contraindicated. Typically, lactose intolerance is caused by a deficiency of the enzyme that breaks down milk sugar, lactase. Diagnosing lactase deficiency in yourself is simple: if after eating dairy products you experience flatulence, abdominal pain, or, even worse, diarrhea, then you can safely assume lactose intolerance;

- glucose-galactose malabsorption.

This symptom is a congenital malabsorption of two sugars - glucose and galactose. Such patients cannot tolerate foods containing glucose and lactose (dairy products);

- children under 18 years of age (according to alternative data - up to 13 years for the treatment of influenza and ARVI and up to 18 years for prevention);

- pregnancy.

The effect of Ingavirin during pregnancy has not been studied. Therefore, the drug is categorically not recommended for use during this period;

- lactation.

Despite the high sales and popularity of Ingavirin, it is still unknown whether the drug passes into breast milk. However, given the very modest clinical studies of the drug and the complete lack of testing in pediatric practice, it is extremely undesirable to use Ingavirin during breastfeeding.

How can an overdose occur?

Overdose can only occur if the patient intentionally exceeds the doctor-recommended dosage of this medication

This is why it is important to adhere to a reasonable dosage regimen, as prescribed in the instructions for the drug, or recommended by the attending physician.

If negative reactions of the body occur due to an increased amount of the substance consumed, you should seek medical help. To normalize a person’s condition, even before the doctor arrives, you need to rinse his stomach, then take sorbents.

In general, if the instructions are followed, the drug is well tolerated by children and adults. Occasionally, adverse reactions may develop due to individual intolerance to the active or auxiliary components.

Despite the lack of clinical studies of the effect of Ingavirin therapy on driving, it is generally accepted that the drug does not affect this process in any way (because it does not have sedative or other side effects on humans).

Analogs

Is it possible to take other antiviral drugs if the doctor prescribed Ingavirin? Experts do not recommend doing this, because calculating the correct dosage of an immunomodulatory agent is quite difficult. To do this, you need to consult with your doctor.

Analogs are cheaper than Ingavirin:

Arbidol (price: 180 rub.). The drug has a pronounced inhibitory effect on influenza A and B viruses by stimulating cellular immunity. The tablets can be used for children from 2 years of age and during pregnancy (in emergency cases). Widely used for combination therapy for bronchitis, pneumonia, intestinal and herpetic infectious diseases.
Kagocel (price: 260 rub.). It produces beta and alpha interferons in the human body, which have persistent antiviral activity. The drug does not cause mutagenic or carcinogenic effects, therefore it has virtually no adverse reactions.
Viferon (price: 390 rub.). The drug is available in the form of rectal suppositories, which can be used for immunostrengthening therapy for young children from the first days of life. The drug contains highly active antioxidants that have anti-inflammatory and regenerating properties.
Grippferon (price: 315 rub.). The immunostimulating agent is widely used to prevent colds and flu. Available in the form of drops and nasal spray. Can be used to treat infants. Suitable for adults as well. There are practically no side effects, since the drug is non-toxic and non-allergenic. It can be taken with antibiotics, but only after consulting a doctor.
Tamiflu (price: 1290 rub.). An expensive generic that is widely used for the prevention and treatment of influenza and ARVI. The drug has some differences from Ingavirin, which lie in the mechanism of action on the virus. The active substances included in its composition act as follows: they create a kind of shield that prevents infection from penetrating into the upper respiratory tract.

How much does Ingavirin cost? The cost of Ingavirin varies between 490 rubles. (children, 60 mg) and 520 rub. (adult, 90 mg).

Ingavirin - composition of the drug

The described medication is available in the form of capsules containing one active ingredient - vitaglutam or pentanedioic acid imidazolylethanamide, which has an antiviral effect. The auxiliary part of the product Ingavirin has the following composition:

Aerosil;
potato starch;
lactose;
Magnesium stearate.

The capsule shell contains:

dyes (diamond black, Ponceau 4R, patent blue);
titanium dioxide;
gelatin;
Azorubine

Release form

Ingavirin for throat is available in capsule form for oral use. This means that it is consumed internally. The capsules are red or yellow. The amount of active ingredient in the capsule directly affects its color.

The package contains seven capsules of the drug. You must take the medicine strictly in accordance with the instructions that come with the package.

The contents of the capsule are standard for similar forms of medications: a gelatin shell, inside of which there are white or cream-colored powder granules.

The drug, produced in a yellow pack, contains 60 mg of the main component, and capsules from a red pack - 90 mg. The dosage is adjusted by the doctor depending on what form of the disease a person has and the severity of it. Thus, for the treatment of severe infections, more frequent use of the drug at the maximum dosage is indicated.

Contraindications

Ingavirin is one of the safest antiviral drugs. During the studies, rare restrictions on use were identified that were associated with an increased risk of complications.

Known contraindications:

Carrying a child.
Age up to three years.
Intolerance to any component of the capsule.
Lactation period.
Lack of lactase enzyme.
Intolerance to milk sugar, glucose or galactose.

Age restrictions depend on the dose of the active ingredient in one capsule.

How much and how to give

To figure out how to take Ingavirin correctly, you should read the information below:

It is allowed to take the drug at any time of the day, but the same for the entire period of therapy;
Ingavirin does not need to be taken only after or before meals;
the product requires oral administration with obligatory washing down with water;
to obtain the best effect from drug therapy, it must be started no later than 2 days after the onset of the first catarrhal symptoms;
a child aged 7 to 17 years should take 1 capsule of Ingavirin (up to 13 years, its dosage is 60 mg, after 13 years - 90 mg):
the drug is taken once a day;
The duration of therapy may vary from five to seven days; it depends on the severity of the disease and the specific ARVI viruses that caused the pathology.

Adult patients (over 18 years of age) can take the drug at a dosage of 90 mg for preventive purposes, after contact with ill people. This reception should take place once a day, it can last no more than a week.

When a child experiences the first signs of a viral infection, manifested by a cough, runny nose, and fever, Ingavirin should be started immediately. The sooner drug therapy begins, the faster the body will cope with the infection.

Substitutes, analogues of Ingavirin , are present in a wide variety on pharmacy shelves:

Kagocel: a Russian-made drug, actively used for the treatment of influenza virus, herpes, and other viral infections. Children can be admitted from the age of three.
Isoprinosine: The medicine contains an active substance called inosine pranobex. It has an effect on cytomegalovirus, the measles element, the causative agent of herpes. In children, this remedy can be used after 3 years.
Arbidol: this medicine contains umifenovir, a component that is active against influenza and other viral diseases, including rotavirus, coronovirus. It has several dosage forms: the suspension is approved for children from the age of two, capsules, tablets - from the age of three.
Amizonchik: this antiviral drug contains enisamium iodide. The drug is available in the form of a syrup with a sweet taste, which allows it to be used to treat children from three years of age.
Orvirem: this type of syrup is used to treat children from one year old. It contains rimantadine, which actively affects influenza and acute respiratory infections viruses.
Amiksin: the composition of the drug contains tilorone, a component that activates the production of interferons by the human body. This remedy is in the form of tablets and is used only in children from the age of seven.

Compatibility

Ingavirin should not be taken simultaneously with other antiviral medications - this will increase the negative toxic effect on internal organs, but will not lead to a greater therapeutic result.

Is it possible to take Ingavirin with antibiotics?

The use of Ingavirin with antibacterial agents has not been studied and is not recommended - this medicine is used for viral diseases, and antibiotics help eliminate the negative effects of bacteria.

With alcohol

It is strictly prohibited to use the medicinal product together with alcoholic beverages, as this will significantly weaken the body’s protective functions, reduce the effect of treatment and have a strong negative impact on the functioning of the liver. Drinking alcohol is allowed 3 days after finishing taking the drug.

Do not take Ingavirin with alcohol

Beneficial effects

The drug is characterized by a strong inhibitory effect on influenza particles, as well as respiratory infections. It should be taken for prevention during seasonal exacerbations. It is expressed by the following clinic:

reducing the time of fever;
less manifestation of intoxication (headache, general weakness);
suppression of external manifestations (sore throat, runny nose);
reducing the duration of the disease;
eliminating the risk of further complications.

Ingavirin is an antiviral agent that does not have a detrimental effect on pathogenic microbes. Therefore, it makes no sense to take the drug for a bacterial infection; in this case, the use of antibiotics is required.

Cheap Analogues of Ingavirin

Like many drugs, Ingavir has a number of cheap analogues, among which the following products are worth noting.

Altabor or Ingavirin, which is better?

Altabor is the cheapest analogue of ingavirin among the listed medications. It costs 195 rubles per pack of 20 capsules in a pack . It is taken orally 3-4 times a day, two tablets at a time, depending on the specific indication. The product slowly dissolves until completely dissolved. It consists exclusively of natural components - altabor (tannic acid), which has a complex antiviral effect on the body. Altabor or Ingavrin – which is better? It is worth paying attention to the fact that the dosage of Altabor is inconvenient - you need to drink the medicine often and, despite the lower cost, you will have to purchase more packs of the drug for the course of treatment.

Yodantipyrin or Ingavirin, what to choose?

Yodantipyrine is a Russian analogue based on iodophenazone. The active substance has antiviral, anti-inflammatory, immunostimulating and immunomodulating properties. Thanks to yodantipirin, the body’s immunity is strengthened, which makes it more difficult for the virus to affect the body, and the medicine also fights tick-borne encephalitis. How much does Yodantipyrin cost? Its average price is 320 rubles per package of 50 tablets . Which is better - ingavirin or yodantipirin? It is better to choose the first option of the drug, since the dosage is convenient - once a day, iodantipyrine is taken 2-3 times a day, and it is more suitable for combating tick-borne encephalitis. Few people are suitable for the treatment of viral respiratory diseases.

Ingavirin or Amizon - comparative characteristics

Amizon is a Ukrainian-made antiviral drug. Available in tablet and capsule forms; one package contains 10 or 20 tablets; there are children's forms. It has a wide range of uses and suppresses viral activity well. Which is better - amizon or ingavirin? Amizon is less convenient in terms of dosage - you need to take several tablets 3-4 times a day, but its range of prescriptions is much wider, so both remedies are good. The price is about 60 rubles per plate , but domestic pharmacies rarely have this drug among their assortment.

You might be interested in: Instructions for using Arbidol for children.

Patient reviews

The medicine Ingavirin helped many. Reviews from some patients indicate that already on the second day of using the drug, their condition significantly improved and their temperature decreased. Some say that the very next day after taking the capsules they felt completely healthy, but they did not stop the course of treatment and did not feel any unpleasant consequences. There are also reviews that three weeks after using the medicine, some patients became infected with influenza again, but the disease was milder.

However, not everyone tolerates the antiviral drug Ingavirin equally well. Reviews from patients also contain information that the medicine caused heartburn, stomach pain and attacks of dizziness in some. Apparently, such symptoms are associated with the individual characteristics of the body. There may be an allergic reaction to certain components of the drug. One way or another, such comments exist, and they are worth taking into account.

There is a third opinion about the drug "Ingavirin". Reviews from some patients indicate that the medicine did not have any pronounced effect on them. They say that within the recommended time of taking the drug (five to seven days), the body itself can easily cope with the flu, and “miracle” capsules only help drug manufacturers, and not in terms of health, but in terms of material well-being. Such patients expect immediate action from an antiviral drug, forgetting that each of us has individual characteristics, and, unfortunately, panaceas for all possible influenza viruses have not yet been invented.

In general, patients have good impressions after using the drug Ingavirin. Medical experts also leave similar reviews. This antiviral remedy has not yet been tested by time, but has already won loyal supporters. However, any new medication should be taken with caution. Remember this and be healthy!

How to take the antiviral drug "Ingavirin" for a cold

The antiviral drug "Ingavirin" is based on an active substance that was invented in the 70s of the last century with the aim of using its ability to combat cancer. For the first time, a previously unknown dicarbamine was synthesized, capable of stimulating the process of production of leukocytes in various forms. This quality has been actively used in complex therapy of oncology, against the background of the use of chemotherapy and radiological irradiation. Throughout the clinical use of the substance, active work has been carried out to study its properties and spheres of influence on the human body. The scientific research was carried out by the doctor who first synthesized dicarbamine, A. Chuchalin.

In 2005, based on the obtained clinical studies, a practical test of the substance was carried out in the treatment of viral pathologies. In 2009, a new antiviral drug, Ingavirin, went on sale in the pharmacy chain and was widely used in the fight against one of the most powerful influenza epidemics. During the course of prescription by doctors, it was found that this drug reduces the long hyperthermic period by almost 2 times, reduces the catarrhal manifestations of colds and flu and eliminates the risk of complications.

Due to the existing history of clinical trials over 40 years, we can say with confidence that specialists know for certain all the pharmacological properties, contraindications and dosage of this substance. In this article you can learn about how to take Ingavirin for colds, flu and for the purpose of their prevention during seasonal epidemics.

Antiviral "Ingavirin": tablet composition and action

Antiviral "Ingavirin" is a patented and clinically tested drug that can interrupt the process of duplicating the RNA of the virus and its subsequent introduction into a living cell of the human body.

What are Ingavirin tablets for colds, sore throats and flu?

It’s worth starting with the fact that there are absolutely clear indications for its use, these are:

ARVI and acute respiratory infections caused by microorganisms of viral etiology;
influenza of various types;
adenovirus and respiratory syncytial infection (especially in immunocompromised individuals);
prevention of seasonal colds.

Ingavirin, taken in accordance with the doctor’s recommendations for colds and flu, allows you to achieve positive dynamics in the course of the disease:

the duration of the acute period is reduced by approximately 1.5-2 times (if a cold lasts approximately 7 days without taking an antiviral drug, then with such therapy, performance returns after 3 days);
elevated body temperature normalizes lytically (smoothly) within 24 hours from the start of treatment;
symptoms of general intoxication are quickly eliminated (headache and muscle pain, chills, dizziness, increased sweating go away);
catarrhal symptoms (nasal congestion, sore throat, runny nose, sneezing and cough) are significantly reduced;
the addition of secondary bacterial microflora and the subsequent development of purulent complications is practically not diagnosed.

How to drink Ingavirin: dosage of the drug

Before taking Ingavirin, you should consult your doctor and exclude all possible contraindications to taking this medication. It is prescribed for both prevention and active treatment.

Ingavirin dosage for adults
Common types of flu	90 mg 1 time per day for 7 days
ARVI, acute respiratory infections and other colds	60 mg (2 capsules of 30 mg each) 1 time per day for 5 days
Preventative treatment	90 mg in the morning daily for 7 days

"Ingavirin" and alcohol: contraindications and side effects

In most cases of clinical use of the drug, no side effects are registered. But this does not mean that the drug is completely safe and does not have a toxic effect on the tissues of the human body. In particular, such an effect can occur if Ingavirin and alcohol are combined: toxic hepatitis may develop and the therapeutic effect of the drug may be completely eliminated.

There are contraindications for Ingavirin, which include the following factors:

individual intolerance to the components of a pharmacological agent;
childhood (up to the age of 18);
period of childbearing and breastfeeding.

The need to perform actions that require increased concentration are not contraindications for taking the drug. However, it is worth considering that the clinical manifestations of a cold can themselves reduce concentration and performance and increase the risk of occupational injuries.

Is it possible to drink Ingavirin during pregnancy and for children?

These two questions currently do not have a clear and convincing answer, since the amount of testing being carried out does not provide a clear picture of the effects of the components on the embryo and growing tissues of the child. A number of publications allow the use of Ingavirin during pregnancy, but only if the expected risk to the mother’s health exceeds the threat to the unborn baby. If possible, it is better to give preference to other forms of prevention and treatment of influenza and colds during pregnancy.

Is it possible to take Ingavirin while breastfeeding if the mother’s condition is severe and requires antiviral treatment?

Everything is much simpler here. During the period of therapy and for 5 days after the end of treatment, breastfeeding is stopped. At this time, the baby is transferred to artificial feeding.

"Ingavirin" is not prescribed for children, even after they reach adolescence. Although some medical sources allow experimental use of the drug by children over 13 years of age. The standard adult dosage is used. At the moment, there are no known side effects of these therapies.

NasmorkuNet.ru

Ingavirin or Ergoferon?

One of the common reasons for visiting a pharmacy is the need to purchase antiviral drugs. Which of these antiviral drugs should I choose to reduce the severity of symptoms, shorten the overall duration of treatment, and prevent the development of complications?

Use only as directed by a doctor

What is the difference between Ingavirin and Ergoferon: the first is a medicinal product, while the second is homeopathy.

Contains vitaglutam, has anti-inflammatory, antiviral and immunomodulatory activity. Acts on adenovirus, influenza virus, parainfluenza.

The antiviral mechanism is based on suppression of virus reproduction. Normalizes the level of interferon in the blood. Anti-inflammatory property: inhibits the production of anti-inflammatory cytokines.

Take orally once for up to 7 days. Start of use no later than 1.5 days from the first symptoms. For preventive purposes - immediately after contact with the suspected source.

It is excreted unchanged, most of it through the intestines.

Intolerance.
Pregnancy.
Breastfeeding (stop for the duration of treatment).
Up to 18 years old.

Allergic reactions develop rarely. Do not use together with other antiviral agents. No studies have been conducted in combination with antibiotics, so co-administration is not recommended.

Russian made. The cost of packaging is 450-500 rubles. Available without a prescription.

The drug "Ingavirin" - 7 capsules

Antiviral and immunomodulatory homeopathic remedy containing antibodies. It is compared with Anaferon because it has a similar composition.

Range of activity: anti-inflammatory, antiviral, immunomodulatory, antihistamine.

Anti-aging peptide serum!

A female stimulant with a quick effect. An effective means of getting rid of hair. Eternal youth of the face is real.

The difference from Ingavirin lies in the prescription for the prevention of acute respiratory viral infections during the morbidity season and in a broader list of indications:

Treatment and prevention of viral diseases (flu, herpes, ARVI, intestinal infections).
Complex treatment of bacterial infections.
Prevention of bacterial complications.

High safety profile and low toxicity.
There is no teratogenic or embryotoxic effect.
There are no immunotoxic or mutagenic properties.
Does not affect reproduction.

Contraindicated in case of hypersensitivity, congenital galactosemia, lactase deficiency.

Available in lozenges, which are taken according to a specific regimen. Can be prescribed from 6 months. For children under 3 years of age, the tablet is dissolved in water. Preventive course for up to 6 months.

Combine, if necessary, with other symptomatic and antiviral drugs.

Country of origin: Russia. Cost (20 tablets) – 290-320 rubles.

So I became a victim of advertising for the drug Ergoferon, because I read that it does not help, but I still decided to check it out. I chewed the tablets according to the scheme, it is a little tricky. On the third day I realized that if I continue to be treated with it, I will end up with bronchitis or some other problem.

One good thing is that the RAS commission is finally obliging us to indicate active ingredients in the instructions for drugs, and to remove homeopathic remedies from the shelves and sell them separately. I have nothing against homeopathy, but I don’t want to prolong the disease with ergoferon treatment.

Once they recommended ingavirin for treatment, but there was no benefit from such treatment. Only two years later I learned that it had no evidence base, no therapeutic effect, no foreign analogues. And they treat it only here. A common commercial interest of pharmaceutical companies, which acts on the placebo effect. This is how you can treat yourself with tap water.

If you carefully read the annotation for ergferon, you understand the dosage - the active ingredients are applied to lactose monohydrate in the form of a mixture of three active aqueous-alcoholic dilutions of substances diluted respectively in 100 * 12 100 * 30 100 * 50, that is, almost until they disappear completely. With this the concentration remains only lactose. Excuse me, but when did we treat viruses with sugar? It’s funny and sad that they sell us sugar under the guise of a “miracle cure.”

Strong dilution is called homeopathy. As long as it is not prohibited from production and release, everyone decides for themselves whether to trust it or not.

There are a lot of antiviral drugs, but they are of little use. I took ergof-n, the scheme is tricky, but this is not the main thing, it does not help in the fight against viruses, and as a preventive measure it also did not show its best side. Waste of money and time.

I am skeptical about antiviral drugs, ergoferon is not a medicine, an ordinary homeopathic dummy, like all homeopathy without an evidence base. The composition alone is worth something, it’s not clear how the substance is diluted to large degrees 100 * 12,100 * 30,100 * 50

Ergof. I definitely wouldn’t choose it, I tried to treat it twice and it was all to no avail. Only a rash appeared on the body, and the fever went away only after antibiotics.

If an antibiotic helps you, antiviral drugs are powerless. And I have tested ergoferon and ingaverin on myself more than once. Ingaverin is a strong remedy. Helps. Erg. The main thing is to start taking it on time, as soon as the symptoms begin. And strictly according to the plan. With his help, they have coped with the disease more than once. You need to approach taking medications wisely. Health to everyone!

There is no need to test the effectiveness of antiviral drugs with an antibiotic. Most acute respiratory infections are of a viral nature and ATB is usually not needed, and if it is needed, then you need to know exactly which one and from what.

Side effects

The media is non-toxic and is not absorbed into the blood, so the risk of side effects is minimal. If intolerance to one of the substances included in Ingavirin is detected, an allergy may occur.

If you are intolerant to the components of Ingavirin, an allergic reaction on the skin may occur.

At what age can children be given Ingavirin 60 mg

Many parents are interested in the age at which Ingavirin is allowed. It is not prescribed to children under seven years of age. The medicine also has other contraindications that you should familiarize yourself with before taking it.

What does Pancreatin help with, who should take it and how should it be taken correctly?

The drug is often used in pediatric practice. Experts safely prescribe it to schoolchildren and note that it effectively combats the symptoms of the disease. Children calmly accept the taste of the medicine. It is not bitter and has a sweet aftertaste.

Mechanism of action

A strong medicine is the drug "Ingavirin". Reviews from patients indicate that it quickly relieves fever and other unpleasant symptoms of the flu. This effect is associated with the mechanism of action of the drug. "Ingavirin" affects viruses by suppressing their ability to reproduce (divide). The well-known Swiss drug Teraflu has a similar effect. However, the domestic “Ingavirin” is capable of more: it has a stimulating effect on the synthesis of interferons, and also gives a pronounced anti-inflammatory effect. In this case, the medicine is not retained in the body, but is eliminated from it within 24 hours after administration.

Important information from the instructions

Before using Ingavirin (for children), the instructions included with the drug should be carefully studied by parents. This way you can protect your child from possible unpleasant consequences. The annotation states that antiviral capsules must be taken for the treatment and prevention of viral diseases. The medication is also prescribed for bacterial complications, but in combination with other drugs.

Many consumers are wondering at what age the drug “Ingavirin” (for children) can be taken. If you believe the instructions, then you can use antiviral medicine for children from the age of seven. Some sources indicate that the capsules should not be given to a child under 13 years of age. Even if your child meets the established standards, do not rush to give him a magic pill

Be sure to pay attention to contraindications. The instructions warn that you should not take Ingavirin (children 60 mg or adults 90 mg) if you are hypersensitive to the main substance or intolerant to additional

It is prohibited to use the medicine during pregnancy and lactation (even in pediatric dosage). The medication should not be given to children with lactase deficiency or lactose intolerance. If you decide to give this drug to your child for the first time, be sure to consult with your pediatrician. During treatment, monitor your baby's reaction. If unexpected and unusual reactions occur, be sure to tell the doctor who prescribed you about them.

additional information

To give Ingavirin for children to a small patient, he must be at least seven years old. Children younger than this have not been studied clinically. Therefore, the manufacturer cannot guarantee that the drug will be safe. Don't risk your baby's health. If he is under seven years old, then use other antiviral medications. Some of them will be presented to your attention later in the article.

Laboratory studies have shown that the drug "Ingavirin" does not cause disturbances in the functioning of the central nervous system. Therefore, it can be combined with driving

When using capsules, you do not have to give up important work, since your concentration does not decrease

The manufacturer does not recommend using the anti-inflammatory immunomodulator together with other antiviral agents. At the same time, other types of medications are perfectly combined with Ingavirin. It is used with antibiotics, antipyretics, immunomodulators, and antiparasitic complexes.

The medicine is produced in Russia by Valenta Pharm OJSC. Ingavirin is sold without a prescription in many pharmacy chains. Keep the medicine out of the reach of children. The room temperature should not exceed 25 degrees.

Evidence base

In 2009, the drug Ingavirin was tested in humans. Reviews of the study indicate that the medication significantly reduces the duration of fever during influenza (duration - 34.5 hours). This figure is much lower than when using the advertised Arbidol (48.4 hours) or taking a placebo (72 hours). Another result of the trial was the absence of toxic effects when using the drug. Unfortunately, there is no other official evidence of the effectiveness of the drug yet. However, many praise Ingavirin. Reviews from specialists on specialized forums indicate that its effectiveness has been confirmed by practice. Below we will talk about what patients think about this medication.

Alcohol during treatment

Ingavirin cannot be combined with alcoholic beverages, since the active substance of the drug reacts with ethanol, which significantly affects the effectiveness of treatment. Moreover, Ingavirin inhibits the process of alcohol elimination by the liver, which increases its toxic effect. Consequently, any drinks containing alcohol reduce the effectiveness of treatment to almost zero.

And since the load on the liver increases, taking Ingavirin if you drink alcohol will not only be completely useless, but also harmful. It is worth noting that doctors recommend abstaining from alcohol for another two to three days after completing the course of treatment.

General information about Ingavirin

Ingavirin is an antiviral drug produced by Russian manufacturers. The medication has an anti-inflammatory effect and stops the process of virus reproduction and the spread of infection to healthy cells.

Ingavirin is available in capsules for oral administration with the active ingredient - pentanedioic acid imidazolylethanamide (vitaglutam). The medicine is not an antibacterial agent and differs from it in its mechanism of action. A medicine with low toxicity, so it has a wider scope of application than an antibiotic.

Description of the drug

The drug does not have any harmful effects on the body - carcinogenic and immunotoxic effects, as well as mutagenic effects on cells. Over the course of 5 days of taking the medication, it begins to accumulate in the body, so the drug is not prescribed for longer than 7 days, 1 capsule per day.

The reasons for prescribing the medication are the following signs of influenza viral agents invading the body and the onset of disease progression:

weakness of the whole body and pain in joints and muscle fibers;
dizziness and pain in the temporal and frontal parts of the head;
fever and fever;
nausea and sometimes vomiting;
intoxication of the body, which can cause diarrhea;
catarrhal diseases.

Mechanism of action of Ingavirin

The medicine is not prescribed if you are allergic to the components, as well as for children under adulthood.

Ingaverin has not been studied during pregnancy and breastfeeding, so it is not recommended to take it during this period. If treatment with this particular medication is absolutely necessary, it is necessary to consult a gynecologist about the advisability of taking the medicine by nursing and pregnant women.

You need to start taking the medication from the first hours of the development of the pathology, then the effect of the medicine will be maximum.

Adverse reactions

There have been very few clinical studies conducted in the field of studying Ingavirin and its effects on the human body. They have not been completed to this day, so newly emerging circumstances, side effects, contraindications that are determined during such studies are periodically included in the instructions for the drug.

As a rule, the medication is tolerated by patients without any possible side effects. Occasionally, people experience changes in the normal digestion of food, dyspeptic disorders may develop, and heaviness may appear in the epigastric region. Some patients complained of allergic reactions in the form of a rash on the skin, accompanied by itching.

If such reactions occur on the part of the body, you should stop using ingavirin and seek medical help.

Which is better for children - Kagocel or Ingavirin 60

Kagocel belongs to synthetic antiviral drugs from the group of interferon inducers. The drug has antiviral and immunostimulating effects.

The cost of a package of Kagocel is 260 rubles. The drug is produced by the Russian pharmaceutical company Nearmedic Plus.

Just like Ingavirin, Kagocel is used for the prevention and treatment of influenza and other acute respiratory viral diseases.

The mechanism of Kagocel's antiviral activity is based on its ability to stimulate the processes of interferon synthesis by the patient's body.

Kagocel is recommended for the treatment of patients over six years of age, however, if necessary, the drug can be prescribed to children over three years of age.

Read further: Instructions for Kagocel tablets + a lot of useful information

Ingavirin movement to Olympus

For almost five years of existence on the pharmaceutical market, Ingavirin was able to break into the top ranks of the ranking of drugs for influenza and ARVI. Sales rates break records in the autumn-winter period and are steadily growing from year to year. And this despite the fact that Ingavirin is contraindicated for use in children.

It's time to remember that Russian pharmaceuticals have produced several antiviral drugs over the past ten years. Among them, Arbidol, Kagocel and, of course, Ingavirin are known to every conscious citizen of the CIS today. The homeopathic Anaferon should also be included in the host of domestic remedies for the flu.

Against the background of this optimistic information about the achievements of domestic pharmaceuticals, the fact that not a single Russian antiviral drug, including Ingavirin, has been registered in non-CIS countries looks very sobering.

Nevertheless, the chief therapist of the Russian Federation, Alexander Chuchalin (inventor of Dicarbamine), responsibly declares that Ingavirin is in no way inferior in effectiveness to the French Tamiflu. It should be noted that Tamiflu is a world-recognized leader among drugs that act against the influenza virus. The drug has successfully passed many large placebo-controlled studies and has proven highly effective.

In this article we will try to figure out what Ingavirin is. Is it really an excellent remedy for influenza and ARVI or just a promoted advertising project with a placebo effect?

>>We recommend: if you are interested in effective methods of getting rid of chronic runny nose, pharyngitis, tonsillitis, bronchitis and persistent colds, then be sure to check out this page of the site after reading this article. The information is based on the author’s personal experience and has helped many people, we hope it will help you too. Now let's return to the article.

Drug safety

The drug Ingavirin 90 is relatively safe. Reviews from experts strongly advise using this drug against the most severe forms of influenza. Doctors justify their position with the following facts:

This medication significantly reduces the risk of relapses and complications.
Taking the medicine does not depend in any way on the diet.
The drug "Ingavirin" has a proven safety profile.
The drug does not have a local irritant, allergenic, immunotoxic, or mutagenic effect on the body.
The medication does not have reproductive toxicity or carcinogenic activity.
The drug Ingavirin is recommended by the Ministry of Health and Social Development for the treatment of swine flu. Instructions and reviews of the medicine indicate its high effectiveness against this disease.

Directions for use: special instructions

Instructions for use of Ingavirin note that the children's version of this medication is used only from 7 years of age (from 3 years of age, despite widespread misconception, this drug is not allowed to be used). Capsules for children have a reduced (compared to an adult) dosage of the main active ingredient; in capsules it is equal to 60 mg of vitaglutam.

Another dosage, equal to 90 mg, can be used for preventive and therapeutic effects in children from the age of thirteen and adults. It should be taken into account that experts do not recommend the use of Ingavirin tablets for preventive purposes in children until they reach the age of majority.

Before using a pharmaceutical product, be sure to read the instructions; it indicates for children at what age this medication can be used.

The method of using this medicine involves taking it orally, followed by drinking a small amount of water. The capsule can be taken without paying attention to the time of eating. The only important thing is to take Ingavirin approximately the same daily (at the same time of day).

Children's immunity is weaker than adults. For children, timely initiation of therapy is especially important, so taking the drug should begin from the moment the first symptoms of a viral infection appear.

Pharmacological properties

The antiviral effect of the active substance of the drug Ingavirin is based on stimulating the functional activity of its own interferon, increasing endogenous, i.e., formed in the body, interferon in the blood.

The drug suppresses the synthesis of virions in the nucleus of an infected cell, inhibits the migration of synthesized particles to the site of assembly of a new virus.

The immunomodulatory effect of the drug is:

in increasing the activity of NK cells with high killer activity;
increased production of gamma and alpha interferons by leukocytes;
production and specialization of cytotoxic lymphocytes.

The anti-inflammatory effect is manifested:

inhibition of pro-inflammatory cytokines;

Interleukin 6:
interleukin 1 beta;
tumor necrosis factor;

blocking the activity of myeloperoxidase, an enzyme of neutrophils (a type of leukocyte), which has a damaging effect on blood vessels;
reducing symptoms of colds such as runny nose, lacrimation, inflammation of the conjunctiva of the eye.

Pharmacokinetics

The active substance Ingavirin was initially studied for use as an immunomodulatory agent for the treatment of cancer patients. The dosages of vitaglutam used in these studies were significantly higher than those used as an antiviral agent.

This explains the fact that, despite the properties of the compound being studied, much of its behavior in the body remains unstudied. Thus, the drug is not detected in the blood by available methods after administration.

Although, when studying the properties of vitaglutam as part of the antitumor drug Dicarbamine, it was found that it is quickly absorbed in the stomach and enters the blood, evenly distributed throughout the body.

The active substance is not metabolized in the body and is excreted unchanged in feces (77%) and urine (23%). The elimination period is 24 hours, during which about 80% of the compound is removed.

Description

Unfortunately, there are no drugs that guarantee 100% protection against influenza. But nevertheless, there are remedies that help eliminate the first symptoms of the disease. Ingavirin is one of these drugs. Taking the medicine does not cause complications, it is completely safe and is eliminated from the body in full throughout the day.

The effectiveness of treatment largely depends on how quickly the course began. If it is not possible to start treatment within the specified time frame, the drug will have a less effective effect.

Contraindications for antiviral drugs

Taking medications is contraindicated:

when breastfeeding;
if lactose intolerance is detected;
during the period of bearing a child;
if you have intolerance or hypersensitivity to one of the ingredients.

Under 18 years of age, it is not recommended to take the drug in the adult form.

Do not take Ingavirin while breastfeeding

How to take Ingavirin

The drug is intended for internal use. Its action does not depend on diet. The medicine should be used no later than 2-3 days after the onset of the disease. One-time use during the day includes:

Blue and red capsules: 90 mg per day for adults (i.e. 1 piece red or 3 pieces blue), children 13-17 years old 60 mg per day (i.e. 2 pieces blue).
Yellow capsules: children 7-17 years old, 60 mg per day (i.e. 1 piece).

The duration of the course takes from 5 to 7 days. The duration depends on the severity and illness of the patient. For preventive purposes, Ingavirin should be taken for a week in the dosages established for the age group. You should not open the capsule and pour out its contents when taking the drug. The shell is edible and soluble.

If it is necessary to take the drug during lactation, you will have to stop feeding the baby milk. Further feeding should be continued after the active substances have been completely removed from the body and only after agreement with the attending physician.

Instructions for using Ingavirin in our video:

Release form and composition of Ingavirin

Before you buy Ingavirin for your child, remember that the drug is popular among adults. The 90 mg dosage is not suitable for small children and adolescents and is even dangerous. The reason is elementary - the child’s body is less strong and resilient, the physiological processes in it proceed somewhat differently. Therefore, for the treatment of children, Ingavirin is purchased in children's form.

In pharmacies Ingavirin is sold in the form of red capsules in a dosage of 90 mg with the active substance vitaglutam. Excipients are:

powder contains lactose, potato starch, aerosil, magnesium stearate;
The shell contains gelatin, titanium dioxide, and crimson dye.

The children's product has a dosage of 60 or 30 mg. The capsules are packaged in blisters of 7 pieces, which are packed in a cardboard box. The manufacturer of Ingavirin for adults and children is the large Russian company Valenta Pharma. It was she who previously produced the drug Dicarbamine with a similar effect in the form of tablets.