Is it possible to take Ranitidine for gastritis of the stomach or not?

Gastritis is a disease that can lead to extremely serious consequences. Therefore, if such a diagnosis is made, you need to be treated persistently and regularly. Moreover, self-medication should be categorically excluded, since therapy is prescribed taking into account individual indications.

Thus, it is advisable to use Ranitidine for gastritis if the inflammatory process is accompanied by increased secretion. If secretion is not changed or reduced, then the use of this medicine may be harmful.

Description of the drug

• inhibition of digestive acid secretion;
• decrease in the amount of gastric juice;
• relieving irritation from inflamed walls;
• relief of heartburn, reduction of belching force;
• activation of local immunity;
• launching regeneration processes.

The drug is excreted naturally in the urine after 24 hours.

• heartburn with belching;
• inflammation of the esophagus due to the backflow of acidic gastric contents;
• stomach and intestinal disorders.

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The active formula contains ranitidine hypochloride in the form of white powdery granules with a pungent odor and a bitter aftertaste. Auxiliary compounds are sodium lauryl sulfate, cellulose microcrystals, colloidal silicon dioxide, magnesium stearate. In smaller quantities, the composition included titanium dioxide, hypromellose, ethylcellulose, polyethylene glycol, corn thickener (starch), and dye.

• for a long time reduces the secretion of digestive juice and acid concentration;
• slows down the action of microsomal enzymes;
• creates protection for the cellular layer of the mucosa;
• relieves the severity of a painful attack.

Indications for use

Ranitidine is used as part of complex therapy for gastric and duodenal ulcers, Zollinger-Ellison syndrome, reflux esophagitis, erosive esophagitis, chronic dyspepsia, accompanied by pain in the chest area. Ranitidine can also be used to prevent:

• ulcers caused by stress;
• ulcerations in peptic ulcers;
• bleeding from the upper gastrointestinal tract;
• secretion of gastric juice caused by surgical operations under general anesthesia.

The drug can also be used to treat ulcers caused by the use of non-steroidal anti-inflammatory drugs.

The drug has no serious contraindications, which means that it can be used by patients who have not only problems with the gastrointestinal tract, but also concomitant diseases.

First of all, the drug is not approved if you are intolerant to ranitidine and the excipients contained in the tablets. Also, the drug is not recommended for use by children under 12 years of age, since there is no data yet on how safe it is for them. Since the drug easily penetrates the placental barrier and into breast milk, it is also better for pregnant and lactating women to avoid it, although there is currently no direct evidence that it can harm the baby.

Ranitidine is designed for the treatment of pathologies of the stomach and other gastrointestinal organs:

1. Stomach ulcers during exacerbation.
2. Duodenal ulcers during exacerbation.
3. Erosive esophagitis.
4. Zollinger-Ellison syndrome.
5. Ulcers in the gastrointestinal tract that occurred as a result of strong external influences (poisoning, stress).

What else do Ranitidine tablets help with? The medication has proven itself to be effective in preventing exacerbations with bleeding of gastrointestinal ulcers, as well as acid aspiration pneumonitis.

Contraindications

A complete ban on treatment with Ranitidine:

• intolerance to components;
• age less than 15 years;
• breast-feeding;
• pregnancy.

Ranitidine should be taken with caution in cases where the disease is accompanied by cirrhosis of the liver. Liver as well as renal failure, as well as the acute form of porphyria, are also good reasons to use Ranitidine only when absolutely necessary.

In addition, visual impairment and accommodation paresis (temporary dysfunction of the eye lens) may occur. As a rule, the patient does not experience the absolute majority of side effects after taking Ranitidine, and if they are present, they are in such a mild form that the patient may not notice them.

Contraindications and overdose

• pregnant and lactating women;
• children under 14 years of age;
• cores;
• patients with nervous system problems.

If the permissible dose (maximum) is exceeded, convulsions appear, heart rhythm is disturbed, hallucinations appear, and fainting is possible. This situation requires urgent medical intervention.

If an overdose occurs with tablets, the stomach must be rinsed before the ambulance arrives. If migraines, allergies, irritability and overexcitability occur, the patient should consult a doctor regarding the development of side effects for reassignment or correction of the treatment regimen.

Treatment of gastritis is complex and consists of taking drugs with different spectrum of action. Ranitidine is most often prescribed for gastritis, especially in cases where the disease is chronic and is accompanied by increased secretion of gastric juice.

Stomach diseases. Use of ranitidine

Ranitidine is relevant for the treatment of gastric ulcers or chronic gastritis, in which there is increased secretion of gastric juice. An excessively acidic environment has a negative effect on the stomach, destroying the integrity of the internal surface.

If an ulcerative process is already underway on the surface, the influence of strong acidity can become fatal. Progressive disruption of the stomach walls leads to bleeding. They are associated with the destruction of blood vessels that pass through the walls of the stomach. It can even end with a perforation of the stomach, which will result in peritonitis - inflammation of the abdominal cavity.

Therefore, ranitidine is indispensable in the correction of increased secretion of gastric juice, because it reliably blocks its excessive secretion. This drug can not only treat existing pathology, it is used for prevention.

If the condition is corrected due to exacerbation of gastritis or peptic ulcer, ranitidine is taken 150 mg 2 times a day. You can replace two doses with one time before bed. But in this case, they immediately take the daily dose - 300 mg. Treatment lasts for one to two months. If prophylaxis is carried out, 150 mg or 300 mg is prescribed. The specific dosage is determined by the doctor. Take a pill before bed.

pharmachologic effect

Ranitidine belongs to the group of histamine receptor blockers of the gastrointestinal mucosa.

1. Significantly and permanently suppresses the secretion of gastric juice, including its acidity.
2. Inhibits microsomal enzymes.
3. Protects the cells of the gastric mucosa.
4. Reduces the feeling of pain.

The above pharmacological actions make it possible to use this drug for the treatment of gastritis, including for its prevention.

The danger of uncontrolled treatment of gastrointestinal diseases: a doctor says

The drug is named after its active ingredient, ranitidine.
There are 2 types of tablets that differ in dosage: 300 and 150 mg. The protective film consists of agents that disintegrate in the intestines. Among the additional chemical agents used: silicon dioxide colloid, microcrystalline cellulose powder, magnesium stearate, copovidone. Ampoules contain 25 mg of active substance per 1 ml; accordingly, if a full 2 ​​ml ampoule is used, the patient is given an injection of 50 mg.

Ranitidine was originally created as an antiulcer agent. The active component is a synthetic substance from the group of blockers of special receptors responsible for the release of histamine (H2). Their role is to have a complex effect on the secreting goblet cells of the stomach along with gastrin, caffeine, pentagastrin, pepsin, acetylcholine for the formation of gastric juice. Histamine acts like a hormone and stimulates the synthesis of hydrochloric acid. It is “recognized” only by H2 receptors.

Under normal conditions, the quantitative indicator of acidity depends on the food received. It supports the initial digestion process, affects the microflora, crushing and mixing of the bolus, and the speed of transportation to the duodenum. In patients with stomach pathology (gastritis, ulcers), the mechanism for regulating acid production is disrupted. Excess leads to erosion of the mucous membrane, the formation first of a focus of inflammation, then erosion and deep ulcers.

Due to the stagnation of the food bolus, the possibility of reverse (reflux) reflux of contents into the esophagus appears. The patient suffers from heartburn from the effects of acid on the mucous membrane of the lower part. Food is not digested properly, which leads to disruption of subsequent enzymatic processes in the gastrointestinal tract (GIT).

In addition, increased acidity creates a convenient habitat for Helicobacter pylori infection, which is considered the main cause of peptic ulcer disease in 70% of patients. Ranitidine suppresses increased acid production, pepsin activity and stimulates the physiological defense of the stomach against internal acid aggression.

As a result of the use of the drug, conditions for scarring of the ulcer, activation of anti-inflammatory processes due to active microcirculation in the wall of the stomach and small intestine, and the supply of nutrients are improved. The symptoms of the disease gradually disappear.

When taken as a tablet, the medicine is quickly absorbed in the intestine. The presence of food in the stomach does not affect the flow of the drug into the bloodstream. The maximum concentration is determined after 2-3 hours. Further metabolism of the substance depends on the condition of the liver cells. Complete conversion to oxide and desmethylranitidine occurs in 5-9 hours. Speed ​​is individual. It is believed that the therapeutic dosage in the patient’s blood is maintained for 10-12 hours.

Excretion from the body is ensured mainly through urine; a small part of the substance is removed during defecation.

The properties of the drug determined its main indications:

• gastric or duodenal ulcer in the acute phase;
• the presence of signs of bleeding in the initial areas of the gastrointestinal tract, their prevention;
• gastroesophageal reflux disease;
• inflammation of the esophagus with cracks in the mucosa (erosive type of esophagitis);
• prevention of the formation of “stress” ulcers and seasonal exacerbations;
• pre-anesthesia preparation for the upcoming operation to prevent gastric juice from entering the respiratory tract;
• chronic hyperacid gastritis;
• consequences of long-term treatment with non-steroidal anti-inflammatory drugs;
• acute pancreatitis;
• digestive disorders with nausea and pain in the epigastric area after eating;
• consequences of infectious gastroenteritis;
• Zollinger-Ellison syndrome is a benign pancreatic tumor with increased production of gastrin, accompanied by a stomach ulcer.

It has been established that substances that block histamine H2 receptors suppress the negative effects of non-steroidal anti-inflammatory drugs and protect the stomach wall from ulceration. Therefore, the need for admission may arise in patients with systemic lesions of the joints and spine.

Ranitidine is loved by patients because it is cheap and accessible. Doctors are critical of the drug. On medical forums they directly write that “there are more side effects than beneficial ones.” When prescribing the drug, the doctor is not sure that the patient is using it correctly; he often observes “rebound syndrome” after discontinuation, signs of overdose:

• drowsiness;
• skin rashes;
• headache and dizziness.

It is impossible to foresee them in advance.

Patients with uncontrolled use experience very negative consequences:

• in a blood test - a decrease in the number of leukocytes and platelets;
• on the ECG - the appearance of atrioventricular block;
• complaints of constipation or diarrhea, pain in the liver area;
• fatigue;
• visual impairment;
• women stop menstruating, men experience impotence, and the mammary glands become enlarged;
• pain in muscles and joints;
• hypertension;
• hair loss.

Rarely observed:

• attacks of shortness of breath due to bronchospasm and other allergic manifestations;
• confusion to the point of hallucinations;
• recurrent parotitis.

Doctors know that during treatment with Ranitidine, laboratory test data (liver tests, creatinine) are distorted.

Ranitidine is used for diseases of the digestive system with caution, after a preliminary examination of the patient. Not recommended as first aid. The drug is strictly contraindicated for self-administration in order to get rid of the symptoms of gastritis, ulcers, and food poisoning.

Bibliography

1. Fundamentals of clinical pharmacology and rational pharmacotherapy: A guide for practicing physicians, ed. Yu.B. Belousova, M.V. Leonova. M.: Bionics, 2002.
2. Zhandarov K.N. The use of H2-histamine blockers in complex conservative therapy of acute pancreatitis. Medical news 2007 No. 2 pp. 53–55.
3. Gorsky V.A. et al. Antimediator therapy in the complex treatment of acute destructive pancreatitis. Journal named after N.I. Pirogova, surgery, 2010, No. 3, pp. 54–61.
4. Bloom Stewart, Webster George Handbook of Gastroenterology and Hepatology. GEOTAR-Media M. 2020
5. Gastroenterology and hepatology. Clinical reference book. Practical medicine M. 2012

Application

The drug ranitidine is available in tablet form and is prescribed exclusively by the attending physician as a systematic course. The drug is used regardless of the time of meal, and it is recommended not to chew the tablets, but to swallow them immediately and then wash them down with a small amount of water.

For adults and children over the age of twelve, doctors prescribe 150 milligrams twice a day, that is, in the morning and evening. If necessary, the single dose is increased to 300 milligrams.

The duration of treatment is four to eight weeks. Long-term use of ranitidine reduces the aggressiveness of pepsins, which destroy the stomach's own tissue.

Scope of application

This drug is intended for the treatment and prevention of stomach ulcers . In addition, ranitidine is prescribed for the following diseases:

• For the prevention of aspiration pneumonitis.
• With erosion of the walls of the stomach due to taking non-steroidal anti-inflammatory drugs.
• For pancreatic adenoma.
• This remedy is used to prevent bleeding in the upper part of the stomach.
• It is prescribed after gastric surgery to prevent stressful situations.
• For inflammation of the mucous membrane.

The main function of this drug is to reduce stomach acidity . The maximum concentration of beneficial substances occurs 3 hours after taking the drug. More than 60% of ranitidine hydrochloride is excreted through the kidneys and about 30% through the feces.

Contraindications for use and side effects

This drug is contraindicated in pregnant women, since the active components of ranitidine penetrate the placenta into the child’s body. It is not used during lactation and for treating children under 12 years of age. The drug is contraindicated in case of individual intolerance to the components of the drug.

Side effects include the following symptoms:

• Skin rash.
• Decreased sexual desire.
• Tinnitus and dizziness.
• Drowsiness and increased fatigue.
• Arrhythmia.
• Irritability.
• Bronchospasm.

This drug is incompatible with alcohol. If you drink alcohol during the course of treatment, heart rhythm disturbances occur . If the drug is taken once, then to avoid side effects, a time period of at least 14 hours should be observed. When taken for more than one week, its concentration in the blood is quite high. After stopping the course of treatment, you should pause for at least 5 days and only then drink alcohol.

Directions for use and dosage

The tablets are taken half an hour before meals. The dosage of the drug depends on the nature of the disease. Typically, ranitidine is used as follows:

• To prevent the formation of ulcers or gastritis, one tablet 2 times a day.
• After surgery for a stomach ulcer, half a tablet of ranitidine 2 times a day. The duration of the course of treatment depends on the patient’s condition and can last from 14 to 60 days.
• During an exacerbation of a stomach ulcer, the patient takes 300 mg of the drug 2 times a day.
• To avoid complications after surgery, the patient takes one tablet before surgery and one after it.
• For Gallinger-Ellison syndrome, one ranitidine tablet is prescribed per day.

This medicine is part of a complex treatment and is used for various diseases of the gastrointestinal tract.

The drug has proven itself very well in the treatment of gastritis and pancreatitis. For heartburn, it is recommended to take half a tablet of ranitidine . It perfectly relieves spasms and colic in the pancreas during pancreatitis. In case of exacerbation of the disease, instead of tablets, a solution of the drug is administered intravenously.

Side effects

Ranitidine, like any other medicine, has side effects, these include:

• nausea;
• vomit;
• stool disorder;
• lowering blood pressure;
• dizziness;
• headache;
• drowsiness;
• blurred visual perception;
• various allergic reactions.

The use of Ranitidine for gastritis is practiced by many patients. The medicine is quite effective and easily tolerated by patients, minimizing side effects. Ranitidine for gastritis helps reduce the acidity of gastric juice, improve well-being and increase the production of beneficial enzymes. In our new material, you can find out in what forms of gastritis Ranitidine will be useful and how advisable its use is in exacerbation of gastritis with high acidity.

In pharmacies, this medication can be purchased in orange tablets. If necessary, you can buy medicine that will be in the form of injections. Another good option is effervescent tablets that can dissolve in lukewarm water.

Characteristics of the drug

Contraindications to treatment

Despite the high effectiveness of such a drug in eliminating various pathologies of the gastrointestinal tract, in some cases its use will have to be abandoned. Ranitidine has a high level of metabolism, so some of its components are able to penetrate the placenta and breast milk. It is for this reason that it is not recommended to take this medicine when treating diseases in women during pregnancy and lactation.

One of the contraindications to treatment with Ranitidine is children under 14 years of age. The drug contains chemical compounds that can negatively affect the functioning of the nervous and cardiovascular systems.

Patients may complain of:

• frequent headaches;
• sleep problems;
• increased irritability and depression;
• dizziness and faintness;
• attacks of nausea and vomiting;
• pain in the abdominal area;
• anemia;
• cardiopalmus;
• allergic reactions.

Treatment with Ranitidine should be carried out with increased caution in those patients who suffer from impaired liver and kidney function. The fact is that the medicinal components included in the drug can accumulate in these organs.

If the required dosage is exceeded, the patient may experience convulsions and hallucinations, as well as heart rhythm disturbances and fainting. In such a situation, it is necessary to call an ambulance as quickly as possible. Before the doctors arrive, it is advisable to perform a gastric lavage, but only if the pills were taken. Ranitidine for gastritis is prescribed only by a specialist, since its uncontrolled use can provoke the development of various complications.

https://youtu.be/3lWZ-4_rXtE

How to take Ranitidine for gastritis

For gastritis, Ranitidine is prescribed only if the disease is chronic and the patient has increased secretion of gastric juice. The drug has a blocking effect on histamine receptors, which are supplied to the gastric mucosa. This leads to a decrease in gastric juice.

The area affected by inflammation does not experience irritation, so local immunity is activated and regeneration processes are launched. The described drug creates favorable conditions for the healing of wounds and erosions, eliminating other symptoms of inflammation of the gastric mucosa, but only if you know how to take Ranitidine for gastritis.

As a rule, Ranitidine is taken for gastritis only after careful diagnosis and weighing of all identified symptoms. The dosage is calculated on a strictly individual basis.

Ranitidine is taken for gastritis only after careful diagnosis and weighing of all identified symptoms

General rules for taking the drug Ranitidine for gastritis;

• For the treatment of gastritis, adults are prescribed 300 mg per day, this dose is divided into two doses - morning and evening. If necessary, a single dose of 300 mg is taken strictly at night;
• The tablets can be taken before or after meals. They do not need to be chewed; the medicine is swallowed with water;
• The minimum course of treatment is a month. The maximum is two. You can no longer take Ranitidine if you have gastritis. Active substances reduce the activity of pepsins and prevent the destruction of the stomach walls;
• injections are most often used to prevent internal bleeding.

During long-term use of the drug, some side effects may occur. Numerous studies have shown that headaches, causeless irritability and instability of the nervous system often appear. During therapy, attacks of depression and severe dizziness were noted. Patients experience sleep disturbances and a mild panic attack.

In addition to allergic reactions, tachycardia and arrhythmia often occur. The patient may experience nausea, which is accompanied by vomiting. Side effects can be minimized if you know how to take Ranitidine for gastritis. Since any medications have the ability to accumulate in the liver and kidneys, doctors pay attention to the fact that the described drug must be used with extreme caution in the treatment of kidney and liver patients.

Treatment regimen for gastritis

How should patients with gastritis take Ranitidine? The dosage and duration of therapy is determined by the treating gastroenterologist. As a rule, for gastritis with high acidity, the following dosage regimen is recommended:

• daily dose 300-450 mg (depending on acidity readings);
• if necessary, the daily dosage can be increased to 900 mg;
• you should take the drug 2 or 3 times a day, dividing the daily dosage into equal parts;
• if the drug is prescribed for prophylaxis, then you need to drink 1 tablet containing 150 g. active substance, at night;
• if the patient is diagnosed with kidney disease, then it is necessary to reduce the dosage to 75 mg twice a day;
• if intramuscular or intravenous administration is necessary, it is recommended to use 50-100 mg of the active substance for procedures every 6-8 hours.

Rules for taking Ranitidine for gastritis with high acidity

A gastroenterologist, when prescribing drugs for the treatment of the gastrointestinal tract, can prescribe Ranitidine for gastritis. This medicine is suitable for patients with increased secretion of gastric juice, i.e. it cannot be prescribed for low stomach acidity. This medicine is necessary in order to adjust the amount of hydrochloric acid produced. Therefore, it is often used for gastritis with high acidity.

It helps to cope with this disease, and is also an excellent means of prevention, because prevents inflammation of the gastric mucosa if the body produces too much hydrochloric acid. Indications for use of this drug: increased acidity of gastric juice, heartburn and belching. Can be used for erosive gastritis, because helps heal ulcers and erosions, it immediately relieves the symptoms of the disease.

Principle of operation

Ranitidine tablets reduce the production of hydrochloric acid and digestive juice, and at the same time, increase the volume of protective mucus, which prevents the appearance of ulcers. But, in addition, the medicine is effective for stomach pain, helps relieve heartburn and belching, and also activates the immune system, relieves irritation and eliminates foci of inflammation. The histamine blocker, which is Ranitidine, takes an active part in eliminating any intestinal and gastric disorders. The drug is excreted naturally through urine 24 hours after the dose is taken. The components of the medication do not have a negative effect on the endocrine gland and genitourinary system.

Indications and contraindications for taking Ranitidine for gastritis

Before deciding to use a histamine receptor blocker, consult your doctor. The drug is effective during the period of seasonal manifestations that occur in spring and autumn, in the treatment of exacerbations. Some treatment regimens for gastritis involve complex therapy, which is implemented by combining ranitidine and bismuth-containing drugs. They have an antibacterial and protective function, which is used in the role of preventive and therapeutic care for the patient.

The instructions state that Ranitidine is effective in cases of increased acidity; it is not prescribed for those with low acidity. Use is permitted only after reaching the age of 14; objective testing of the drug has not been carried out on children, therefore it is conditionally considered a medicine for adult patients of a gastroenterologist.

The doctor determines the dose individually, the standard measure is 150 mg in the morning and before bed or 300 mg at night. Tablets are available with both amounts of the main active ingredient. The course of treatment can last 30 - 45 days; after the symptoms of exacerbation are relieved, the tablets are used only before going to bed. The product should not be chewed and should be taken with a sufficient amount of liquid.

Not knowing how to take ranitidine for gastritis, during, before or after meals, patients seek an answer from a doctor. The instructions state that the absorption of the substance does not depend on nutrition; it is allowed to take the tablet both before meals and after a certain period of time.

The parallel use of Ranitidine tablets with alcohol and enveloping agents (antacids), sorbents is undesirable, as their degree of absorption is reduced. There is evidence that smoking and smoking have a negative effect on treatment with a histamine receptor blocker.

Composition and beneficial properties

The release forms of this drug are film-coated tablets and solution for injection. The tablets are packaged in blister packs of 10 pieces each. Each box can contain from 2 to 10 tablets in blisters.

Chemical composition of ranitidine

The active ingredient of this drug is ranitidine hydrochloride . The tablets contain 150 or 300 mg of the active ingredient. The amount of ranitidine hydrochloride in ampoules does not exceed 2 ml.

Ranitidine: features of use for gastritis

Ranitidine for gastritis is one of the most popular antacid drugs. The taken medication continues to be active for 12 hours, which eliminates the need to take the drug after each meal.

Ranitidine is used to treat gastritis with high acidity and provides the following therapeutic effect:

• reduces the amount of gastric juice secreted, thereby preventing the eruption of digested food into the esophagus;
• normalizes the acidity level of gastric juice, significantly reducing the aggressive effect of enzymes on mucous tissues.

The drug is classified as potent. An overdose or prolonged use on a regular basis can cause many side effects.

Before use, you should consult your doctor; it is strictly not recommended to use the medication on your own.

Before use, you should consult your doctor; using the medication on your own is strictly not recommended.

Like other H2-histamine blockers, ranitidine should not be discontinued abruptly. With long-term therapy in patients with a weakened immune system, there is a risk of bacterial damage to the stomach and further progression of the infection. There is also information that the medicine can provoke acute manifestations of porphyria.

It is recommended to use the substance 2 hours after using ketoconazole or itraconazole. This will help avoid a significant decrease in the absorption of these drugs. The drug can also increase the effect of glutamate transpeptidase.

Ranitidine can provoke a false-positive reaction when performing a test for protein components in the urine. The medicine can counteract the effects of histamine and pentagastrin on acid synthesis in the stomach. Therefore, it is prohibited to use ranitidine 1 day before the test. The substance provokes the suppression of skin reactions to the action of histamine. This provokes false positive results. Before performing skin tests to diagnose allergies, you should stop taking this medication.

Contraindications

Contraindications for use are:

• individual intolerance. If signs of an allergy appear, you should consult a doctor to select a safe analogue;

• age under 14 years;
• pregnancy;
• lactation.

The drug is prescribed with great caution if the patient has impaired functioning of the urinary system. Before starting treatment, you should make sure that there are no malignant neoplasms in the upper gastrointestinal tract.

So, Ranitidine is prescribed for diseases caused by increased secretory function of the stomach. This remedy should not be used for self-medication, since the dosage and duration of the course of administration are determined individually. The drug can be used as part of complex therapy, but it is recommended to take it 1-2 hours before taking another pharmacological agent.

Reviews about the drug Ranitidine

Ranitidine is an effective drug that successfully copes with various digestive disorders. To achieve good results, it is important to strictly follow your doctor's recommendations.

Numerous reviews of ranitidine indicate the high effectiveness of the drug

Numerous reviews of ranitidine indicate the high effectiveness of the drug:

• Natalya: I was prescribed ranitidine after treating a duodenal ulcer in a hospital setting. I took 1 tablet before bed and continue to take it when the first symptoms of discomfort appear. I didn't notice any side effects;
• Varvara: A very effective remedy is ranitidine. The doctor prescribed it to me to eliminate the symptoms of a peptic ulcer. The drug helped me personally in a short time. Thanks to its use, unpleasant symptoms disappeared and well-being improved;

Side effects and contraindications

Like all medicines, Ranitidine has contraindications for use. It is strictly forbidden to use the product in the following cases:

• pregnancy;
• lactation;
• children under 12 years of age;
• hypersensitivity to the components of the drug;
• atrophic gastritis;
• low acidity in the stomach.

Like all drugs belonging to the same group as Ranitidine, it tends to provoke the development of side effects with long-term use, for example:

• skin rashes;
• decreased platelet levels in the blood;
• increased prolactin levels;
• increased fatigue;
• loss of coordination;
• general weakness;
• bad feeling;
• hair loss.

As a rule, stopping taking it stops the body’s negative reaction, but in especially severe cases, serious deviations can develop, and if a person suffers from some chronic diseases, then death. It is imperative to notify your doctor if you experience tinnitus, depression, or nervous irritation. Also dangerous are negative reactions from the digestive system:

• vomit;
• constipation;
• diarrhea;
• nausea;
• poor appetite;
• abdominal pain;
• discomfort in the oral cavity.

The functioning of the cardiovascular system may be disrupted, which is characterized by symptoms such as rapid heart rate, discomfort in the heart area, arrhythmia, and others.

Reviews

In most cases, reviews of the use of Ranitidine are positive. For several years in a row, the medicine has been a leader in the treatment of heartburn and other symptoms of gastrointestinal diseases. Even with modern medications, which have fewer negative consequences, Ranitidine is not inferior to them and remains in demand.

Reviews from doctors indicate that the remedy is absolutely necessary in the treatment of ulcers and gastritis, since the amount of gastric juice is reduced and its acidity is reduced, which leads to rapid treatment and recovery of patients. The solution can also stop internal bleeding.

special instructions

In case of severe pathology of the renal system, the medication is prescribed with caution. Before using the drug, it is necessary to exclude oncological diseases of the intestines, esophagus and stomach.

Long-term therapy of weakened patients who are in a state of stress can provoke the development of bacterial disease of the stomach, as well as the subsequent spread of the inflammatory process.

If the medication is abruptly discontinued, the risk of relapse of peptic ulcer increases. Preventive therapy is more effective with a course of taking the drug for 45 days in the fall and spring, compared to continuous use.

In patients suffering from various rhythm disorders, rapid intravenous administration of the solution can provoke bradycardia. For persons with a history of porphyria, Ranitidine is prescribed with caution due to the risk of developing an acute attack.

Distortion of laboratory test parameters (liver enzymes, creatinine, GGT) is allowed. The time interval between taking antacids and Ranitidine should be at least 1-2 hours due to the risk of changes in the absorption of the active substance. Clinical studies confirming the safety of the drug in pediatric practice are limited.

Description of the drug

When a person suffers from gastritis, he usually feels pain in the epigastric region, cramping in the abdomen, and nausea.
The abdomen becomes bloated, belching and discomfort appear after eating. In this situation, a person seeks to find suitable tablets for gastritis to reduce pain and discomfort. Typically, patients who have suffered from chronic gastritis for many years already know how to treat gastritis and what tablets for gastritis will help relieve pain, reduce nausea and normalize digestive processes.

If a patient has clinical signs of gastritis for the first time, experiments with self-prescription of drugs cannot be carried out! Before starting treatment and making decisions on the choice of medications, it is recommended to undergo a full examination; based on the results of the studies, the gastroenterologist will prescribe comprehensive treatment and prescribe medications for gastritis.

Today, medicine and the pharmacological industry have not developed a single universal tablet that can eliminate the existing pathogenetic mechanisms and clinical symptoms of gastritis. Drug treatment for gastritis includes:

• Antibacterial agents - trichopolum, furazolidone, amoxiclav.
• Antacids - Gaviscon, Maalox, Rennie.
• Gastroprotectors.
• Antispasmodics and analgesics.
• Proton pump inhibitors.
• Wound healing agents - solcoseryl, actovegin, methyluracil.
• Hepatoprotectors for the treatment of bile reflux - hofitol, ursosan.
• Sorbents – lactofiltrum, activated carbon, smecta, enterosgel.
• Histamine receptor blockers (famotidine) are used less frequently today.
• Means that normalize gastric motility - cerucal, motilium.

When prescribing an adequate course of treatment, it is necessary to take into account the level of acidity. For high and low acidity, different medications are prescribed.

To treat gastritis with low acidity, the doctor prescribes replacement therapy drugs.

For example, gastric juice with pepsin or a number of medications that stimulate the production of hydrochloric acid and digestive enzymes in the stomach.

To improve the digestive process, enzymes are used - mezim or creon. The drugs help relieve pain and prevent bloating and flatulence.

If the acidity of the gastric juice is high, drugs with antacid properties, proton pump inhibitors, are prescribed. A number of treatment regimens for gastritis and gastric ulcer have been developed.

Antacid tablets

The list of antacid medications includes tablets:

• Rennie.
• Maalox.
• Gastal.
• Gaviscon.
• Alumag.

Medicines are used in combination with drugs that are proton pump inhibitors. The complex is quite effective. Antacid substances are incompatible with gastroprotectors. For a good therapeutic effect, you will have to take a break between taking medications for at least 2 hours.

Antacids contain aluminum compounds. Interacting with digitalis preparations, tetracyclines and salicylates, aluminum forms insoluble compounds that cause harm to the body.

The combined use of medicinal groups is contraindicated. It is important to know which medications can be taken in combination and which ones are best avoided. Only a doctor can provide such a recommendation.

In addition to tablets, Almagel suspension is widely used.

The therapeutic mechanism of the drug for the stomach is extremely simple. The medication contains magnesium and calcium carbonates, which in the stomach interact with hydrochloric acid of gastric juice.

After just a few minutes, taken Rennie neutralizes the acid, water and neutral insoluble salts are formed in the stomach, which are removed from the body through the kidneys or intestines.

This is an effective remedy for relieving pain and heartburn due to gastritis and peptic ulcers.

Gastal

Combined gastric drug. Contains compounds of aluminum and magnesium. The active compounds of gastal interact with stomach acid and form neutral insoluble salts and water.

The resulting salts have a mild laxative effect by relieving spasm of intestinal smooth muscles. The resulting aluminum salts are colloidal compounds and attract large quantities of water, intensely protecting the mucous membranes of the stomach and intestines.

This remedy is an excellent cure for heartburn and abdominal pain due to gastritis.

Gastritis is often caused by a bacterial infection, and antibiotic therapy is prescribed to eliminate it. Antibiotics are used that are active against Helicobacter pylori infection and are stable in the acidic gastric environment. Suitable products include:

1. Clarithromycin.
2. Amoxicillin.
3. Amoxiclav.
4. Trichopolum or metronidazole.
5. Furazolidone.

These drugs for gastritis are highly active against the causative agent of gastritis, and are used for hyperacid gastritis and gastritis with decreased acidity. At the same time, you should take probiotics. Instead of tablets, it is possible to take the fermented milk product acidophilus.

Gastroprotectors

The drug group has a direct protective effect on the gastric mucosa.

Medicines for acute gastritis protect the epithelium from the effects of external aggressive factors - acids, enzymes, alkalis, chemically active substances.

As a result of exposure to a number of pharmacological drugs, drug-induced gastritis develops. Effective and frequently used drugs are Venter and De-nol.

De-nol

Another name for the drug is bismuth tripotassium dicitrate. In addition to the protective effect, it has high activity against the bacterium Helicobacter pylori. By interacting with the acid contained in gastric juice, the drug forms a protective film that creates mechanical protection for the stomach wall, especially in areas of ulceration.

Sucralfate

Another name for the product is venter. It is a salt of aluminum and sucrose. The drug taken in an acidic environment forms a stable polymer that protects the stomach wall.

Do not take the medicine if you have low acidity or with antacids. In the latter case, no protective polymer is formed.

A properly formed film adheres to the walls of the stomach, creating a protective coating that reliably protects against the effects of aggressive factors.

The drug belongs to a type of gastroprotector. An example of a group is the drug misoprostol.

It helps to increase the protective properties of the epithelium of the mucous membrane and its resistance to external influences. The active substance prostaglandin is synthesized in the epithelial cells of the gastric mucosa.

It plays an important role in the normal functioning of the mucosa. Prostaglandins perform the following functions:

1. Increases the regenerative ability of cells.
2. Improves blood circulation in the gastric mucosa.
3. Reduce the secretion of hydrochloric acid in parietal cells.
4. Increase mucin synthesis.

This treatment is effective for gastritis caused by long-term use of non-steroidal anti-inflammatory drugs. Often exacerbation of gastritis occurs in patients taking aspirin, paracetamol, thromboass.

During exacerbation of peptic ulcer disease, the prescribed drug is less effective. A side effect that limits its use is the frequent development of diarrhea. If you have chemical or drug-induced gastritis, drinking medicine is quite useful.

The substances are used in the treatment of gastric ulcers and gastritis with high acidity; they help reduce the production of hydrochloric acid by inhibiting the enzyme sodium-potassium ATPase.

Thanks to this pharmacological group, the acidity of gastric juice is reduced and signs of the inflammatory process are stopped. The representative of the group is the drug Omez (omeprazole). Previously, group 2 antihistamines, in particular Famotidine and Ranitidine, were widely used to reduce the synthesis of hydrochloric acid.

However, recently Omez has replaced the mentioned components due to its high efficiency. The product has the best effect.

For preventive purposes, it is convenient to use omez simultaneously with long courses of thromboass drugs and steroid hormones. The drug paracetamol has less effect on the gastric mucosa and is taken once if necessary.

This group of drugs is used as a symptomatic remedy to eliminate pain due to gastritis. The mechanism of action is due to the relief of spasm of smooth muscle cells.

Thanks to the effect, the pain goes away and the movement of the food bolus through the digestive tube improves. Such drugs include drotaverine (no-shpa), halidor, papaverine.

Thanks to these medications, the pain goes away in a matter of minutes.

A number of antispasmodics have an effect on pain centers in the brain, reducing the flow of pain impulses into the cerebral cortex during gastritis of the stomach. These include spazgan, spasmalgon, baralgin.

Other groups of drugs that cure gastritis are known.

Ursosan for gastritis is used to normalize the functioning of the biliary system. Helps neutralize bile acids released into the stomach during reflux gastritis. The drug hofitol is taken for a similar purpose.

To accelerate the healing of wounds and gastric ulcers, the drug methyluracil is widely used. It has an anti-inflammatory effect and promotes tissue regeneration processes. Actovegin has a similar effect. Wobenzym accelerates the healing process and increases the overall resistance of the body. The course of Wobenzym is repeated during periods of exacerbation.

To speed up the removal of excess acid and toxins from the stomach, sorbents are prescribed - enterosgel, smecta, lactofiltrum. You can take cheap activated carbon.

To eliminate the symptoms of nausea and vomiting, normalize the movement of the food bolus and prevent the development of reflux, tablets are used to treat gastritis - cerucal and motilium for gastritis. The drugs help prevent the backflow of food and bile from the duodenum into the stomach, and eliminate the unpleasant symptoms of nausea and vomiting.

Herbal medicine has found wide application in the treatment of gastritis. Plant decoctions - oregano, St. John's wort, chamomile, nettle - allow you to heal ulcers and cure inflammation. It is necessary to brew the herbs with boiling water and drink before meals.

Unlike pharmaceutical drugs, herbs are safer, according to patients, and are inexpensive. It is possible to include acidophilus in the diet during the subacute period of the disease. Alternative medicine (including Ayurveda) offers a number of effective recipes.

Important Features

1. The drug masks the signs of carcinoma in the stomach. Before prescribing, a cancerous ulcer should be excluded.
2. Abrupt discontinuation of the drug is unacceptable due to the risk of rapid relapse of the disease.
3. Long-term treatment of weakened patients exposed to severe stress increases the risk of bacterial infection of the stomach, which can quickly spread to other organs.
4. Incompatibility with Itraconazole and Ketoconazole, which must be taken within 2 hours of using the blocker to avoid decreased absorption.
5. The drug provokes a false positive reaction to the presence of protein in the urine.
6. 24 hours before the test for the acid-forming function of the stomach, which is affected by the concentration of pentagastrin and histamine, you need to o.
7. The drug shows maximum effectiveness when used prophylactically in courses of 45 days. This treatment is prescribed during seasonal exacerbations.

Overdose

Symptoms of overdose are as follows:

• headache and dizziness;
• clouding of consciousness and drowsiness;
• skin rash;
• convulsions;
• bradycardia and ventricular arrhythmia.

If signs of overdose appear, you should call a doctor. Before the first aid team arrives, you should induce vomiting and drink activated charcoal. Additionally, gastric cleansing by lavage and symptomatic treatment will be required:

• to relieve seizures - Diazepam intravenously;
• to eliminate bradycardia - “Atropine”;
• for ventricular arrhythmias - Lidocaine.

Consequences and complications after taking the drug may occur due to improper adherence to medical recommendations or overdose. The use of the drug should be monitored if there are individual characteristics of the patient’s body.

Possible adverse reaction:

• appetite decreases;
• nausea and vomiting appears;
• Constipation or diarrhea occurs.

Sometimes the patient may experience tinnitus, headache, fever or dry mouth, and increased fatigue. Frequently taking the medication will cause a man to experience pain in his muscles or joints, and even show signs of developing impotence. Serious violations include:

• heart and blood pressure problems;
• increased heart rate and heart rate;
• leukocytosis, thrombocytosis;
• severe allergic reaction.

Against the background of an overdose, symptoms such as:

1. Headache, dizziness.
2. Drowsiness, confusion.
3. Skin rashes.
4. Cramps.
5. Bradycardia, arrhythmia.

If the first signs of an overdose appear, you should immediately call an ambulance. While the doctor is driving, the patient must be given activated charcoal or given plenty of water to induce vomiting. After this, gastric cleansing and treatment will be required.

https://www.youtube.com/watch?v=hCetbg8xvxw

In medicine, there are analogues of Ranitidine, for example, Omeprazole. The medicine also effectively eliminates all signs of digestive system disorders, fights heartburn and protects the gastrointestinal mucosa.

The drug is taken under the strict supervision of a qualified specialist. The doctor knows what Ranitidine helps with, and, taking into account all the features of the established diagnosis and the patient, he prescribes the medicine. While the course of treatment lasts, it is necessary to refrain from consuming any foods that negatively affect the condition of the gastrointestinal mucosa. You should also avoid drinking alcoholic beverages.

Operating principle

Ranitidine quickly normalizes the amount of digestive juice, inhibiting its excessive production. This condition is usually provoked by a high food load, for example, when overeating. Juice begins to be actively produced under the influence of hormones and biologically active substances, such as acetylcholine, histamine, gastrin, pentagastrin, caffeine.

The drug enhances the natural protective properties of the gastric mucosa, stabilizes the production of hydrochloric acid in the digestive juice. At the same time, the amount of mucus secretion does not change, and the processes of production of liver enzymes are not inhibited.

Ranitidine helps accelerate the healing and regeneration of damaged tissue of the gastric mucosa resulting from the aggressive effects of gastric acid.

According to the instructions, 150 mg of Ranitidine is enough to suppress the production of digestive juice for 8-13 hours. Coated tablets are quickly, but 50%, absorbed into the blood. The maximum content of the active substance is achieved after 2 hours.

What you need to know before use

The drug is prescribed after the absence of cancer in the stomach, esophagus, and duodenum is diagnosed. If the patient is confirmed to be infected with bacteria, antibiotics are prescribed in combination with ranitidine.

Important! Taking this medicine may affect some tests.

It increases the level of a substance synthesized in muscles - creatinine, which is an important indicator of kidney function. It also provokes the activity of the GGT enzyme.

It is known that Ranitidine, taken to relieve heartburn, begins to act after only 10–15 minutes; in some cases, gastrointestinal diseases are resistant to therapy with this drug.

Ranitidine affects blood creatinine levels

Action of the medicine

Ranitidine is a second-generation H2-histamine receptor blocker. This means that it reduces the production of acid by blocking the cells that produce it. The antisecretory drug also reduces the activity of pepsin, an enzyme involved in the breakdown of protein foods.

It also improves the motility of the stomach and duodenum and promotes microcirculation.

Important! There are analogues of the drug - these are Ranitab, Asitek, Zantac, Peptoran, Ulkosan, etc.

Ranitab is an analogue of Ranitidine

Features of the drug:

1. Protects the stomach by reducing its secretion. This quality of the substance is especially necessary in case of exacerbation of ulcers, in the chronic form of the disease, during the period of multicomponent therapy for gastritis.
2. It is quickly absorbed from the gastrointestinal tract, which is facilitated by the simplified form of the drug.
3. Almost 50% of the main active ingredient is metabolized in the liver, but is excreted through the kidneys (through urine). The drug leaves the body completely after 24 hours.
4. It is also excreted through mother's milk, so if taken by the mother, it is recommended to temporarily stop breastfeeding.

The product can help with night and daytime high acidity, and effectively copes with stress and age-related gastritis. It has been proven that in elderly patients absorption of the drug occurs faster. On average, the tablet begins to act in 1.5 – 2 hours.

Ranitidine is suitable for the treatment of elderly patients