Instructions for use of the drug Mezim Forte

Constipation as a result of poor digestion

Insufficient digestion and breakdown of food leads to various disorders in the body. At the level of the gastrointestinal tract system, this is manifested by colic, spasms, strong abdominal rumbling, constipation or diarrhea. All these changes in well-being usually bother you after a meal. Poor digestion of food negatively affects the entire body; if this disorder occurs constantly, it leads to:

• Vitamin deficiency.
• Severe weakness and poor ability to work.
• The appearance of rashes and pigmented spots on the skin.
• Drowsiness.

Digestive problems do not appear out of nowhere; in most cases, the person himself is to blame for their occurrence. A course of enzyme preparations may be required if constipation and other symptoms of bolus digestion disorders are caused by:

• Constant consumption of unhealthy food. Constipation often occurs in people who prefer to eat fatty, too salty, fried foods, smoked foods and sweets. Excessive and constant consumption of such food leads to significant disruptions in the functioning of the pancreas, liver, and stomach.
• Overeating. Even healthy food eaten in large quantities causes problems with the absorption of beneficial components.
• Poor chewing of food. Thorough chewing of all foods contributes to their better absorption and has a positive effect on the functioning of all parts of the digestive system.
• Eating too late. After about 9 pm, all metabolic processes in the body slow down, and if you eat after this time, the food will take a very long time to digest, causing heaviness, bloating, and constipation.
• Drink plenty of fluids during meals. You should consume as much water as possible, but most of it should be drunk between meals. If you drink food, an excess amount of liquid will dilute the bile, including enzymes, and this will worsen the digestion process.

If the body constantly experiences all of the listed provoking factors of poor digestion, then it may require drug treatment. It is based on preparations with enzymes, under the influence of which the digestion of food bolus will be closer to natural.

Other medicines

If you don’t want to drink expensive lactulose for a long time, use suppositories and microenemas (this most often applies to men), strong laxatives are used. They have many unwanted effects and are not suitable for long-term treatment of constipation and its symptoms.

Magnesium sulfate

Perhaps the most powerful saline laxative. A single dose (20 g) is dissolved in a glass of water. Drink the freshly prepared solution. Effect in about 2 hours.

You should not leave the house at this time. Saline laxatives work powerfully. Magnesia is good for rare constipation.

It is not recommended to use it often; it can cause dehydration and persistent diarrhea.

By using osmotic agents for several months, you can “earn” cardiovascular failure. The drugs interfere with the absorption of potassium and magnesium - this leads to heart failure.

Long-term use of saline laxatives is unacceptable in children, since disturbances in water-electrolyte metabolism can lead to dehydration.

Osmotic laxatives are able to retain water in the intestinal lumen. The stool softens.

The drugs increase the volume of intestinal contents and promote comfortable bowel movements. The drugs raise osmotic pressure by using water from the fatty tissues surrounding the intestines and plasma.

This causes a strong laxative effect of the drugs. The powerful laxative effect of salt remedies is used for poisoning.

Medicines containing bisacodyl (Dulcolax)

These can be suppositories and tablets. They help well with hemorrhoids, hypotonic and atonic constipation. If bowel movement is desired in the morning, take 1-3 bisacodyl tablets in the evening. The action develops over eight hours.

Bisacodyl is the drug of choice for the treatment of constipation accompanied by hemorrhoids and anal fissures. Drugs are used before endoscopic examination. Prescribed for various diets.

Long-term use of drugs in this group leads to dehydration and intestinal atony.

Sena preparations

among them we can highlight “Senade”, “Glacsena”, “Thick senna extract”, “Senadexin”. The initial dose is 1 tablet at night, the effect develops after 8 hours.

Disadvantages of senna preparations: intestinal colic, flatulence, addiction. Suitable only for relieving symptoms and treating occasional constipation.

Buckthorn bark, joster fruit

Gastroenterologists do not like these drugs due to the lack of strict dosing and rapid addiction.

Products containing sodium picosulfate

Among them are “Guttalax”, “Slabilen”, “Regulax” and others. They are good because they do not cause colic and chronic diarrhea. The drugs “work” at the level of the colon, increasing peristalsis.

Macrogol

The pharmacy sells Lavacol, Fortrans, Forlax.

Macrogol is not absorbed into the systemic circulation. It does not cause addiction, disturbances in intestinal motility and dehydration. Therefore, macrogol-containing drugs can be used for up to three months.

Macrogol is well tolerated. It does not cause flatulence, pain, or rumbling in the stomach. His work is aimed at softening stool by increasing the fluid content in it.

The drug is drunk during breakfast, dissolving the sachet in water.

When are enzyme preparations needed for constipation?

A one-time violation of the principles of proper nutrition will not lead to significant changes in the functioning of the digestive organs. If constipation develops at this time, you can eliminate it by changing your diet. Properly selected products for digestion against constipation should not only normalize intestinal function, but should also reduce the load on the stomach and pancreas. Gentle nutrition will help stabilize the enzymatic function of organs, and the process of digesting food will gradually return to normal.

Following a diet helps only if constipation is not caused by pronounced changes in the functioning of the gastrointestinal tract. But if the problem has been going on for many years or arises as a consequence of changes in the functioning of the digestive organs, then a course of taking special means to facilitate digestion cannot be avoided.

Enzyme preparations or otherwise enzymes must be selected by a doctor. When choosing them, the functioning of the gastrointestinal tract, manifestations of disorders, and concomitant diseases are taken into account.

If enzymes for constipation are chosen correctly, then:

• Intestinal function gradually normalizes.
• Undigested pieces of food disappear from the stool.
• All symptoms of poor digestion and constipation are eliminated.

The dose of enzymes should be calculated individually. In case of severe disorders, enzymes must be taken with every meal.

Rules for taking Mezim before an ultrasound examination

For high-quality diagnostics using an ultrasound machine, thorough cleansing of the intestines from gases and stagnant contents is required. The X-ray contrast method also does not give a clear picture without preparation. Mezim is recommended together with laxatives. To complete the scheme you need:

• the day before the scheduled examination, take 1 tablet three times with meals;
• In the evening, be sure to take activated charcoal or Espumisan.

By morning, the contents of the intestines will be released through bowel movements. Diagnosis of the abdominal organs will be possible with maximum clarity and reliability.

The effectiveness of Mezim is confirmed by many clinical trials. But if the rules of administration are violated, it becomes useless or causes harm. The success of therapy depends on the doctor’s recommendations and their exact implementation. Unauthorized actions, even when symptoms disappear, do not lead to recovery.

Types of drugs

Medicines that stimulate the production of enzymes should be prescribed by a doctor. Such drugs are divided into several groups. Each of them is suitable for eliminating certain changes in the digestive process:

• Medicines based on pancreatin are prescribed for poor production of pancreatic juice, increased detection of pepsin and hydrochloric acid in gastric secretions, dysbacteriosis, and congenital disorders of enzyme production. Drugs from this group are Pancitrate, Penzital, Pankreon, Mezim-Forte. A course of taking these medications improves the enzymatic function of the gland, which also has a positive effect on bowel movements.
• Medicines containing pancreatin, bile acids, hemicellulose. These drugs effectively reduce the formation of gases, promote the breakdown of complex carbohydrates, stimulate the secretion of enzymes and improve intestinal motor function during constipation. They are prescribed for constant difficulty defecating, belching, and flatulence. The most famous drugs are Pancral, Festal, Enzistal, Panzinorm, Cotazim.
• Medicines with herbal ingredients. Exocrine function is stimulated by drugs containing rice fungus and papain extract - Nigedase, Pepfiz, Somilase.

We eat right

Poor digestion is most often the result of the person himself. In order not to experience all the “delights” of negative changes in the functioning of the gastrointestinal tract, you need to constantly adhere to the most basic rules of proper nutrition. Compliance with them not only promotes better digestion of food, but also has a positive effect on the functioning of almost all organs and prevents the gain of extra pounds.

Nutritionists advise putting the following recommendations into practice to prevent constipation and combat it.

• Immediately after waking up, you need to drink a glass of cool water in small sips, and have breakfast after 30 minutes.
• You need to eat in small portions.
• Don't overeat.
• Eat spices, onions, garlic, and garden herbs.
• Avoid eating food that is too cold or too hot.
• The diet should contain as many products with natural fiber as possible.
• Drink more.

The condition of the entire organism depends on how accurately the above rules are followed. People who do not neglect the advice of nutritionists almost never have functional constipation and other problems caused by poor digestion of incoming food.

To prevent insufficient digestion of the food bolus and, accordingly, constipation, it is necessary that the following types of products and dishes from them are constantly included in the diet:

• Whole wheat bread.
• Cereals and bran.
• Legumes.
• Fresh berries.
• Avocado.
• Nuts.
• Pears.
• Flax seeds.
• Dried fruits.
• Vegetables.

Poor digestion of food, which causes constipation, can be dealt with on your own. It is enough to reconsider your attitude to your diet and change your diet, and in most cases the work of all organs of the gastrointestinal tract changes for the better in just two to three weeks. Enzyme preparations in most cases are required when pancreatitis is detected, insufficient production of gastric juice and other pathological changes. If the doctor determines the advisability of taking them, then it is necessary to complete the entire course of treatment, this will relieve poor digestion and prevent the development of the most serious complications.

What enzymes should you take for digestion if you have constipation?

More and more often, enzymes are prescribed as part of complex therapy used in the treatment of constipation.
These artificially created microelements significantly accelerate many chemical reactions occurring in the gastrointestinal tract, which is why they help to effectively combat this problem. Enzymes improve the digestion process, they help eliminate seething and bloating, feelings of severe discomfort in the peritoneum, accumulation of gases - other symptoms that often accompany chronic constipation. In the process of digesting food, a variety of chemical compounds are involved, they give rise to different chemical reactions. Some are responsible for the absorption of fats, others - proteins and carbohydrates, so the very name of the drugs used always indicates which enzyme dominates and what type of chemical reaction it participates in. There are several groups of enzymes:

1. Saliva enzymes.
2. Stomach enzymes.
3. Pancreatic reagents.
4. Intestinal enzymes.

Properly selected complexes can improve the functioning of the gastrointestinal tract. In the treatment of constipation, Creon, Mezim or Pancreatin are most often used. Why do specialists prescribe them? In order to answer this question, it is necessary to study in detail the pharmacological properties of each.

Overdose symptoms

When using the drug Creon 10000 in doses exceeding the recommended ones, an overdose may occur. This condition is characterized by hyperuricemia and hyperuricosuria, which are manifested by an increase in uric acid levels, determined during a biochemical blood test. Symptoms of these conditions are:

• pain in joints and muscles;
• increased sweating;
• headache;
• dizziness;
• abdominal pain;
• nervous tics.

To eliminate hyperuricemia and hyperuricosuria, symptomatic treatment is carried out and a suitable diet is prescribed.

Does Creon 10000 help with constipation?

The formula of the drug is based on enzymes produced by the pancreas, so it is most often prescribed in cases where constipation becomes symptoms of diseases associated with pathologies of the described organ. The main active ingredient is obtained from the pancreas of pigs. Its formula is similar to the formula of enzymes produced by the human body. With proper use of the drug, absorption in the small intestine improves, Creon stimulates the production of its own enzymes of the pancreas and intestines, it has been noted that the use of Creon for constipation in children guarantees improved functioning of the entire gastrointestinal tract. Enzymes do not dissolve as they pass through the stomach. The active substances are enclosed in a gelatin capsule, among which are soluble microspheres.

The dosage of Creon for all patients, including children, is made on a strictly individual basis. It is determined by the attending physician, based on the patient’s condition and the severity of his pathological condition. But there are general rules for admission. For example, Creon 10000 is most often prescribed at the initial stage of treating constipation. Creon for constipation in adult patients is recommended to drink two capsules strictly during the main meal and one capsule during a snack. Creon 10000 will be effective only if the total number of capsules taken per day exceeds four doses. It is permissible to drink up to 15 norms per day. The designation of the number 10000 in the name of the described drug shows how many units of enzymes are in a single dose of Creon.

Mezim and children

When to give mezim to a child is stated in the instructions. It is allowed to give the medicine to children from one year of age. Since a baby at this age cannot describe his condition, and the digestive system is still imperfect (like that of an adult), a limited dosage should be prescribed, and strict control by the treating doctor is necessary.

For children under one year old, the doctor may prescribe mezim if the baby is diagnosed with duodenal disease or pancreatitis. The baby should be fed the medicine as follows.

1. Mash the tablet into powder, then dilute with boiled water.
2. The water temperature should be no more than 36-37 degrees.
3. Give the medicine to the baby during bottle feeding.

The baby may regurgitate the medicine or try to spit it out. Mom should not be scared - this is a normal state of the body for the purpose of self-defense.

Self-medication in such cases is unacceptable; in order to avoid absurd consequences, the dose should be limited and prescribed by a doctor.

Attention! If the drug is not diluted with water, ulcers will appear on the oral mucosa. Then you'll have to treat them!

Children's dosage of mezim

Each age has its own dose of enzyme prescribed. Therefore, in order to correctly give the drug to a child, you should study the instructions with special attention. If the child:

• from 1 to 7 years, one tablet should be given up to three times a day;
• from 8 to 12 years old, it is allowed to take 1-2 tablets up to three times a day;
• After 12 years, up to 6 tablets per day can be taken.

If we take the dosage in terms of lipase, we get the following:

• children under one and a half years old can be given up to 50,000 units per day, at the rate of 1 thousand units of active substance per kg of body weight;
• after one and a half years - 100,000 units per day, at the rate of 1.5 thousand units per kilogram of weight; from 12 years old – 2 thousand units.

It is better to give the tablet to the child whole. He should swallow the medicine like an adult and wash it down with regular still water.

The interval between taking tablets should be about 4 hours. The duration of the course of treatment is determined by the doctor. Depending on the condition of the body and the existing disease, patients can take the drug for several days, several months and even years.

List of the best enzyme preparations for digestion

Insufficiency of the exocrine function of the pancreas leads to disruption of the entire gastrointestinal tract. To replenish the missing complex organic substances, special medications are prescribed. The list of the best enzyme preparations for digestion includes products including: pancreatin, bile acids, hemicellulose.

• Pancreatin. Contains enzymatic components: amylase, lipase, protease, which play a fundamental role in the digestion of carbohydrates, fats and proteins.

• Bile acids. Participate in the process of digestion and absorption of food.

• Hemicellulose. It is a polysaccharide necessary for the normal functioning of the digestive system. With pancreatitis, gastritis, dysbacteriosis and some other gastrointestinal diseases, the body's need for it increases.

Current list of the best enzyme preparations for digestion

Enzyme products based on Pancreatin

The main digestive enzyme pancreatin is necessary for enzymatic deficiency. Participates in the process of breaking down protein and fatty foods.

1. Pancreatin (Russia). It is used for functional disorders of the pancreas and stomach.

• Facilitates the absorption of food in the presence of gastrointestinal diseases and overeating.

• “First aid” for bloating and stomach discomfort.

• Eliminates disruptions in the functioning of the intestines in the early stages of pregnancy associated with the restructuring of the body.

Budget digestive enzyme tablets available to all segments of the population.

• Table 125 mg 50 pcs. 45 rubles, 250 mg - 50 rubles.

2. Mezim Forte (Germany). A high-quality product for enzymatic replacement of pancreatic function. Restores its functionality.

In case of excess food, it relieves accompanying symptoms: bloating, increased gas formation, pain, heaviness in the stomach.

Prescribed in complex treatment for diseases of the gastrointestinal tract, liver, and gall bladder.

• Tab. 20 pieces - 60 rubles, 80 pieces. — 240 rub.

3. Pangrol 10000 (Germany). The special formula of the drug leads to a dosed release of pancreatin, which promotes better absorption of food.

• Replenishes excretory insufficiency.

• Relieves pain.

• Effective for chronic pancreatitis.

• Irritable bowel syndrome.

The enzyme to improve digestion is successfully used in pediatric practice in combination with other medications to treat dysbiosis in young children.

Facilitates the digestion of heavy, fatty or coarse plant foods. The dose is easily adjusted and is suitable for patients of all ages.

• Capsules No20 - 250 rubles, No50 - 570 rubles.

4. Creon (USA). An original drug with a good evidence base from the American manufacturer Abbott. Contains pancreatin - the main enzyme for improving digestion in the intestines.

It is used for dysfunction of the natural process of producing pancreatic enzymes. It has a convenient range of dosages for individual selection of therapy from 10,000 units to 40,000 units.

Effective in complex treatment:

• Chronic and acute pancreatitis.

• Cystic fibrosis.

• Intestinal dysbiosis.

He has proven himself excellent in pediatric gastroenterology and surgery.

The drug is more expensive than analogues, but also more effective among existing enzymatic agents.

The risk of side effects is minimized.

• Capsules 20 pieces 10,000 units - 250 rubles, 25,000 units - 510 rubles, 40,000 units - 660 rubles.

About the composition

The instructions for use indicate that the main component of the drug is a dry extract of pancreatin - pancreatic juice with all its enzymes. Amylase is a substance that breaks down carbohydrates. Lipase – separates fats into fractions. Protease – helps digest proteins by breaking down peptide bonds in amino acids. These are the components that make up the tablet. Pancreatin has a characteristic odor that can be felt when opening the package.

Mezim tablets are coated with a special coating. It is needed to ensure that the drug does not come into contact with the acid of gastric secretions. In an acidic environment, enzymes are immediately destroyed. The shell dissolves only in the small intestine, releasing the contents. That is why the tablets cannot be broken or chewed; they are swallowed whole (the enzymes are also extremely bitter), washed down with water.

The drug is available with different contents of the active substance; the designation on the pack corresponds to the amount of lipase. For example, Mezim Forte 10000 contains exactly 10,000 units of lipase. At the same time, amylases - 7500, proteases - 375. Sold in packages of 20 and 50 pieces. They are pink and come in blisters of 20 pieces.

Accordingly, tablets labeled “20,000” contain lipase – 20,000 units, amylase – 12,000, protease – 900. Here the release form is different – ​​white tablets, convex on both sides, in blisters of 10 pieces. You can purchase 10, 20 or 50 tablets.

Mezim Forte without a number on the package contains 3500 IU of lipase. (There are 4200 amylases, and 250 proteases). Blisters are in boxes of 20 or 80 pieces, their shell is pink. Each box contains instructions with directions for use.

The dose of the medicine is prescribed depending on the severity and duration of the disease, age, weight of the person (especially for children) and other factors. Therefore, if a doctor prescribes Mezim 20,000, then you should take it.