Antihemorrhoidal drug Gepatrombin G - reviews

How to use Gepatrombin G

Preparation for application and further actions depend on the dosage form used:
To apply the ointment, you need to wash the anus area without using soap and dry it with a napkin. The ointment should be applied in a thin, even layer on and around the painful area. The procedure must be repeated 2 to 4 times a day. After the painful manifestations of hemorrhoids stop, you need to apply the ointment for about a week. If the hemorrhoids are very inflamed and touching them is painful, then the ointment is applied with light movements. If the pain has passed, then the ointment can be rubbed in. In case of particularly severe inflammatory processes, it is recommended to apply Hepatrombin G on a gauze tampon, apply it to the hemorrhoids and secure with an elastic bandage.

A tip is used to introduce the ointment into the rectum. Insert it into the anus and squeeze a little. Do not inject too much ointment. If the amount is excessive, due to the specific action of lauromacrogol, regeneration processes will not accelerate, but, on the contrary, will slow down. Healthy tissues can also become sclerotic. At the same time, the absorption of subsequent doses of Hepatrombin G is reduced. This means that the damage will take a long time to heal.

Introducing Gepatrombin suppositories

D is best done after defecation, washing and drying the anus area. It is recommended to administer 1 suppository in the morning and before bedtime. Usually the doctor recommends a course of 1-2 weeks. It all depends on the severity of the damage and the characteristics of the body.

When is Gepatrombin G used?

This medicine is prescribed:

1. At any stage of external hemorrhoids;
2. If eczema of the anal area is observed: burning, itching, etc. (except for the cases listed in the contraindications);
3. For cracks and fistulas in the anus;
4. Before and after operations, natural childbirth.

Gepatrombin ointment instructions for use during pregnancy and lactation

This ointment is available in two dosages - 50,000 and 30,000 units. The first of them should never be used by pregnant women, since the product is very quickly distributed throughout the body. And this can lead to the development of heavy bleeding, and even death. During the lactation period, this dosage also cannot be used, as this can lead to a deterioration in the baby’s health.

A dosage of 30,000 units can be used by pregnant women from the third month of pregnancy. In this case, the ointment can be used against hemorrhoids. If the drug in this dosage is prescribed to a nursing woman, the doctor must take into account that the benefit to the mother far outweighs the risk of deterioration in the baby’s health. It is best to switch the baby to breastfeeding while using this medication.

Reviews of the drug Gepatrombin G

You can read various reviews about this product on the Internet. For the most part they are positive. They are written by pregnant women, those who have already given birth, and simply those who are faced with such a delicate problem as internal or external hemorrhoids in the initial stages of its manifestation.

This drug helps people: it reduces pain, relieves swelling, and eliminates itching. You can also leave your review about the drug after reading the article.

Despite the effectiveness of the drug, doctors emphasize that before buying the ointment, you need to go for an examination and consultation with a specialist. If the patient neglects this rule and self-medicates, then Hepatrombin G may not help him. After all, without knowing the degree of neglect of the disease, the characteristics of its course, it is difficult and even dangerous to treat it.

Instructions for use Gepatrombin method and dosage

Gepatrombin gel and ointment are applied to damaged areas 1-3 times a day. It is necessary to squeeze out no more than 5 cm of gel (ointment) and rub it into the skin with light massage movements from bottom to top. For thrombophlebitis and thrombosis, the product is applied to the skin without performing massage movements. If necessary, in case of vein disease, you can use bandages with ointment applied to them (but not gel!).

The drug in the form of a gel must not be applied to skin with compromised integrity (that is, in the case of open wounds), as well as to mucous membranes.

Gepatrombin G ointment is used externally, a thin layer is applied to the anal area and the skin around it 2-4 times a day. If necessary, the ointment can be injected into the rectum.

Gepatrombin G suppositories are administered into the rectum 1-2 times a day; to achieve a better therapeutic effect, suppositories are used after bowel movements.

Gepatrombin C gel is applied in a thin layer 1-2 times a day to the painful area (if there are wounds and abrasions, the gel is applied around them).

The duration of treatment in each specific case is determined by the doctor and depends on the patient’s condition. As a rule, the therapeutic course is 7-10 days. The course of treatment with Hepatrombin G ointment and/or suppositories usually continues until the symptoms of the disease disappear.

Release form, composition and packaging

◊ Ointment for rectal and external use is yellowish-white, translucent, gel-like.

Excipients: solid paraffin – 50 mg, liquid paraffin – 797.11 mg, lanolin – 50 mg, colloidal silicon dioxide – 70 mg.

20 g – aluminum tubes (1) complete with a tip for rectal administration – cardboard packs.

* 1 IU of sodium heparin – anticoagulant activity, corresponds to the activity of 7.7 mcg II of the International Heparin Standard (WHO).

◊ Rectal suppositories, white, conical; on the cut - white, homogeneous.

Excipients: medium chain triglycerides – 1.08 mg, colloidal silicon dioxide – 11.4 mg, solid fat (Novata B) – 1801.2 mg, glyceryl tristearate – 27.5 mg.

5 pieces. – cellular contour packaging made of PVC (2) – cardboard packs.

* 1 IU of sodium heparin – anticoagulant activity, corresponds to the activity of 7.7 mcg II of the International Heparin Standard (WHO).

Doctors’ opinions on the drug and features of use

As an effective anticoagulant drug, Gepatrombin G is most effective if there is a danger of thrombosis of nodes in hemorrhoids. But it is also used to prevent the occurrence of hemorrhoids themselves and to eliminate post-thrombosis manifestations.

Gepatrombin G is often used to prepare a patient for proctological surgery and after it. Also, this remedy, as part of a comprehensive conservative treatment, has helped a huge number of patients avoid surgery for hemorrhoids.

Hepatrombin G has been well studied. Here are the results of a recent study of the drug in one of the domestic clinics:

1. 60 patients with chronic hemorrhoids (equally divided between women and men) regularly, twice a day, used Gepatrombin G suppositories for a month. The results were recorded weekly. It has been proven that the use of this remedy reduces the amount of rectal bleeding from 85% to 5% in the first week. Doctors noted decongestant and antithrombotic effects, and patients spoke of a decrease in pain.
2. Studies have been conducted on the treatment of anal fissures with Hepatrombin G. At the same time, the analgesic effect of the drug, a decrease in the contamination of the wound with microflora, and a low percentage of adverse reactions in patients were noted.

According to the latest data, Gepatrombin G shows an effectiveness of 65% or higher, which makes it possible to successfully treat hemorrhoids in chronic and acute forms.

What is included in Gepatrombin G ointment for hemorrhoids: description and properties of the components

Hepatrombin G ointment for hemorrhoids is a multicomponent drug, since it consists of three active ingredients: heparin, prednisolone and polidocanol.

The auxiliary composition of the drug is represented by liquid paraffin, mineral oils, lanolin and silicon compounds.

Heparin sodium is a substance belonging to direct anticoagulants, under the influence of which blood clotting processes are blocked. Also, due to blood thinning, microcirculation in the tissues of the anus is normalized, the healing of anal tears is accelerated, congestion in the cavernous veins is eliminated, resulting in a decrease in the severity of inflammation.

Prednisolone acetate is a glucocorticoid hormone produced by the adrenal cortex. This substance is characterized by strong anti-inflammatory, antihistamine and decongestant effects, which allows you to quickly relieve the painful symptoms of the disease.

Polidocanol, also called lauromacrogol, is a substance with a venosclerosing effect, which ensures the adhesion of cavernous veins affected by varicose veins by denaturing proteins. Also, this component of Hepatrombin G exhibits a local analgesic effect.

Indications for use

It is used for varicose veins, thrombosis and thrombophlebitis. The ointment is also used for trophic ulcers of the lower leg, and the gel is used as a means of improving healing after surgical interventions.

The ointment is successfully used for hematomas and bruises accompanied by inflammation of tissues, tendons, muscles, and ligaments. This form of the drug is indicated for people suffering from deforming osteoarthritis and neuralgia pain.

Hepatrombin C is most often used by athletes who, due to their profession, often receive injuries accompanied by tendonitis (inflammation of the tendons), tendovaginitis (inflammation of the tendon sheath), bursitis (inflammation of the joint capsule), etc.

Gepatrombin G ointment and suppositories have proven themselves well as an antihemorrhoidal agent. For internal hemorrhoids, suppositories are used; for external hemorrhoids, the drug is used in the form of an ointment. This remedy copes well with thrombophlebitis of the anal veins, rectal fistulas, eczema, and anal fissures. In addition, Gepatrombin G ointment and suppositories act symptomatically, relieve itching, pain and burning in the anal area.

Composition of the drug

Gepatrombin G suppositories are produced in the form of small torpedo-shaped rectal inserts of white color.

The active ingredients of the drug are the following:

• heparin sodium (direct anticoagulant);
• prednisolone acetate (glucocorticosteroid hormone);
• polidocanol (sclerosant substance).

Among the auxiliary ingredients, it is necessary to highlight triglycerides, silicon compounds, glycerol derivatives and solid fat.
Thanks to such a rich composition, Gepatrombin G has a fairly wide spectrum of antihemorrhoidal action.

Instructions for use

When using hepatrombin ointment for hemorrhoids, you must strictly follow the instructions for use, and if its recommendations are corrected by a doctor, then theirs. To treat internal hemorrhoids, it is more convenient to use suppositories, which are administered 2 times a day after cleansing the intestines. If therapy of internal nodes is carried out using ointment, then a special tip is used for its administration, which is put on the tube. The ointment should be squeezed out a little, slightly squeezing the tube. A large volume of the drug in the rectum will easily cause the development of hemorrhoidal bleeding.

External nodes are treated in the morning and evening, preferably after cleansing the intestines. Next, wash with laundry soap. Use a paper towel to dry the area where the ointment is applied. A small amount of ointment is applied directly to the bump and lightly rubbed in with light movements without pressure. The duration of treatment is determined by the doctor depending on the degree of the disease and the speed of action of the drug on the patient.

If there are anal fistulas, anal fissures or eczema in the anal area, then it is necessary to use the composition in the morning and evening. After cleansing the intestines, the affected area is washed with cool water, using laundry soap as an antiseptic. Next, a sterile gauze pad soaked in hepatrombin G is applied to the anal area. It must be replaced after 12 hours.

The standard duration of treatment for any use of the drug should not exceed 2 weeks. In some cases, the attending physician may prescribe longer therapy according to an individual regimen.

Release form

The manufacturer is a Serbian pharmaceutical company.
The drug is available in two forms:

Candles

Medicinal suppositories for rectal administration are packaged in blisters of five pieces.
The package includes 2 blisters and an insert with instructions for use. They are a solid white mass of uniform consistency and conical shape. Melts easily when exposed to heat. Therefore, they need to be stored in the refrigerator. The shelf life of the drug is 2 years from the date of manufacture, which is indicated on the cardboard packaging and on the blister itself.

Available in 20-gram aluminum tubes with screw-on plastic caps. The lid has a pin for piercing the protective membrane, which blocks the access of air to the medicine. The kit includes a tip to facilitate the administration of medication into the rectum, and instructions for use. Everything is packed in a cardboard box.

It has a gel-like consistency, is almost transparent and has a yellowish-white tint. It has a pronounced specific odor of lanolin.

Contraindications

Hepatrombin G has contraindications that must be observed. Violation of them can easily lead to serious consequences for the patient’s health. The proctologist, before prescribing ointment or rectal suppositories, first determines whether such therapy is suitable in a particular case. If it is impossible to use the product, an analogue is selected that will be permitted in this situation and will not cause harm to the patient.

The use of hepatrombin, including those labeled G, is prohibited when patients have:

• intolerance to components of the drug;
• the presence of open bleeding wounds is a contraindication only for the use of ointment. Candles can be used even for bleeding hemorrhoids, since their effect is not so active;
• decreased blood clotting, especially in hemophilia;
• purulent skin lesions at the site of use - the product is also not used if there is purulent inflammation in the rectum, which is possible with advanced hemorrhoids;
• cancerous tumors in the area of ​​application of the product;
• tendency to intestinal bleeding for various reasons - a contraindication applies to the drug in any form for use in the treatment of hemorrhoids and other disorders of the rectum;
• tuberculosis;
• syphilis;
• fungal diseases in the genital area;
• first trimester of pregnancy
• age up to 16 years.

During treatment, in addition to observing contraindications, it is important to strictly maintain the dosage of the drug. If hepatrombin G is applied too often, then due to tissue oversaturation with active substances, a local overdose develops

Against this background, intense bleeding may occur, which will require medical assistance to stop, as well as a significant slowdown in the process of tissue repair. A slight and non-constant excess of the dosage does not cause such an effect and may occur.

If discomfort occurs while using the ointment, this is a reason to consult your doctor. In such a situation, drug intolerance may occur, which becomes a contraindication (it cannot be identified before starting therapy).

Characteristics of drugs

Hepatrombin is a combination medicine that has a wide spectrum of action: it relieves swelling and inflammatory processes, and has an antithrombic effect. The active component of the drug is heparin. Release form: gel. Indications for use:

• vein thrombosis;
• phlebeurysm;
• ulcerative formations on soft tissues caused by injuries, diabetes mellitus and other diseases with impaired blood circulation;
• tenosynovitis;
• inflammation of soft tissues of a non-infectious nature;
• lymphangitis;
• carbuncles;
• mastitis;
• boils;
• extensive bruises, hematomas;
• varicose phlebitis that occurs after surgery, incl. used for the prevention of postoperative phlebitis.

Contraindications for use:

• individual intolerance to individual components;
• trophic ulcers on the lower extremities with open bleeding;
• open wounds on the skin, secondary infections;
• diathesis of hemorrhagic type;
• hemophilia;
• tendency to internal bleeding.

During pregnancy and lactation, the gel is used only if the doctor decides that the positive result of drug therapy is higher than the risks of side symptoms.

In the case of treatment of varicose phlebitis, Gepatrombin should not be rubbed in, but applied to the skin and fixed on top with a bandage or elastic bandage.

Instructions for use recommend applying a thin layer of gel to the affected area of ​​skin and rubbing in with massaging movements. In the case of treatment of varicose phlebitis, do not rub the product in, but apply it to the skin and fix it on top with a bandage or elastic bandage.

The drug is well tolerated by most patients, side effects occur rarely and are manifested by skin allergies - rash, itching, burning sensation, urticaria.

The main active components of Hepatrombin G are heparin and prednisolone acetate. It is produced in the form of ointments and suppositories for rectal administration. The medicine is characterized by a combined effect and is intended for the treatment of external and internal forms of hemorrhoids. The drug quickly relieves pain, eliminates swelling and inflammation. Indications for use are:

• internal and external hemorrhoids;
• anal fissure;
• thrombophlebitis of the veins located in the anus;
• eczema on the skin of the anus.

As a prophylactic agent, the drug is prescribed before and after surgical interventions to eliminate hemorrhoidal disease.

Contraindications:

• hypersensitivity to the components of the drug;
• chicken pox;
• tendency to bleed;
• tuberculosis;
• syphilis;
• the presence of neoplasms of malignant and benign origin;
• infections and fungus on the skin.

Rectal suppositories and ointment are prohibited for use in the 1st trimester of gestation. When breastfeeding, the drug can be prescribed by a doctor only as a last resort and if necessary. During the lactation and gestational period, the medication can be used only for a short time.

Possible side effects: allergic reactions on the skin; rarely, with frequent use of large amounts of ointment, there is a possibility of secondary infection.

The drug Gepatrombin G is intended for the treatment of external and internal forms of hemorrhoids.

It is recommended to use rectal suppositories and ointment at the same time. Directions for use: administer suppositories only after bowel movements. After inserting the suppository, apply ointment to the anal area. For knots, the ointment should be applied carefully, without overusing its quantity and frequency of use, because this may cause bleeding. To relieve exacerbation of hemorrhoids, it is enough to administer suppositories 1 to 2 times a day for 5 days. The medicine can be used during remission to prevent relapses.

Dosage of the drug and its use

Violation of the instructions may lead to complications.
Before using Gepatrombin G ointment, you should thoroughly wash the anal area with plain water (without using detergents) and dry it with a napkin. If the ointment is used externally, then it should be applied to the affected areas two to four times a day. After the pain has completely disappeared, the remedy is used for another week, once a day. It is highly recommended not to exceed the recommended amount of ointment - it should be applied evenly, in a thin layer.

The drug is available in two dosage forms: suppositories and ointment. The most popular therapy is with the help of ointment for hemorrhoids Gepatrombin G, however, there are quite a lot of reviews about the drug Gepatrombin suppositories for hemorrhoids.

For rectal use, a small amount of ointment is injected into the anus using a special tip. The manufacturers of this drug specifically note that using an excessive amount of the drug will have the opposite effect and will significantly slow down healing. As for the effectiveness of the ointment for hemorrhoids Gepatrombin G, the reviews about it are only positive.

Gepatrombin suppositories are placed in the anus once or twice a day. Bowel movements and appropriate hygiene procedures must first take place. The course of treatment is usually half a month, but it may vary depending on individual prescriptions. Consumer reviews of hemorrhoid suppositories Gepatrombin G are no less flattering.

Compound

The active substances in Gepatrombin G suppositories and ointments are absolutely the same:

1. Heparin sodium. Is a powerful coagulant. Prevents blood clotting and prevents the formation of blood clots in hemorrhoids. Reduces vascular permeability and reduces the level of inflammation in the affected area.
2. Prednisolone. It is a hormone produced by the adrenal cortex. It also has anti-inflammatory and anti-exudative properties. Helps eliminate itching and pain in the anus. Prevents the manifestation of allergic reactions.
3. Lauromacrogol. It has a local anesthetic effect, alleviates the patient's condition, alleviating unpleasant symptoms.

Auxiliary components:

1. Migliol 812. In other words, palm oil. Enhances the absorption of the drug.
2. Silica. Favors the healing of cracks and wounds, absorbs the remains of tissue decay, foreign substances and synthesized protein.
3. Glycerol tristearate.
4. Novat V. Vegetable fat to improve absorption.
5. Paraffin in liquid and solid state (used in ointments).

Contraindications

The drug is contraindicated if the patient is hypersensitive to heparin, dimethyl sulfoxide, dexpanthenol and other components.

The gel is not used in the presence of bronchial asthma, severe liver and/or kidney failure, lupus erythematosus, or open wounds at the site of application of the gel.

The drug is contraindicated in case of severe disorders of the cardiovascular system (severe forms of angina, myocardial infarction, stroke, with severe general atherosclerosis).

Hepatrombin C gel is not used in children under 5 years of age, pregnant and lactating women.

Patient reviews

Andrey, 44 years old, Magadan

How hard it is when 2 different medications have almost the same names. I needed a drug for hemorrhoids, and I missed its name when the doctor prescribed it. I bought Gepatrombin, but after a few days of use I didn’t see any results, although the doctor said that the product should work quickly. As a result, I realized my mistake when I studied the instructions. When I started using the right medicine (Hepatrombin G), I managed to stop the exacerbation of hemorrhoids in just 3 days.

Ksenia, 34 years old, Murmansk

After pregnancy, Hepatrombin was used to treat varicose veins on the legs (not to be confused with Hepatrombin G - it is for hemorrhoids and has nothing to do with varicose veins and thrombophlebitis on the legs). The drug is excellent: it quickly eliminates leg pain, swelling and a feeling of heaviness. I’m already taking the second course of treatment and I’m happy with the results.

Sergey, 42 years old, Novosibirsk

Hepatrombin G is an excellent remedy that helps to quickly cope with hemorrhoids, especially if you combine the use of ointment and rectal suppositories. And my wife is being treated for varicose veins and thrombophlebitis with a drug with the same name, but without the letter “G”. It does not have any positive effect on hemorrhoids. I discovered this when I mixed up our tubes without reading the name.

Possible side effects

According to patient reviews, Gepatrombin ointment does its job well, and very rarely leads to undesirable effects. The drug has shown itself to be excellent in the treatment of venous diseases, as well as hemorrhoids. If you use the product strictly following the instructions for use, then side effects are unlikely to occur. But with excessive and prolonged use, patients noticed a rash, hives, and even swelling on the skin. If you notice any side effects, be sure to consult your doctor. In this case, you are contraindicated to use the ointment.

When is treatment with Hepatrombin G ointment carried out for hemorrhoids: list of indications

Hepatrombin for hemorrhoids, according to the manufacturer’s instructions, can be prescribed in the following cases:

• external, internal and combined hemorrhoids;
• inflammation of hemorrhoids;
• anorectal thrombosis;
• eczema in the area of ​​the perianal folds, which is accompanied by severe itching and burning;
• chronic paraproctitis;
• tears in the rectal canal mucosa;
• conservative therapy before hemorrhoid surgery;
• recovery after surgical treatment of hemorrhoids.

The use of Gepatrombin G ointment is permissible only as prescribed by a specialist, since self-medication can aggravate the course of the disease and cause harm to health.

Side effects

Infrequently reported side effects from the use of Hepatrombin G include: pain and redness at the application sites. This is a consequence of an allergy to one of the components of hepatrombin. If you observe this, stop applying the ointment or administering suppositories and consult your doctor. But when used correctly, hepatrombin G is usually effective and does not cause discomfort.

You cannot use this remedy uncontrollably and for a long time, because it contains hormonal components (prednisolone). A doctor should prescribe hepatrombin G to pregnant women. Use during breastfeeding is permitted, but this should also be discussed with your doctor.

Dispensing rules and cost of the drug

You can purchase Gepatrombin G ointment in Russian pharmacies without a doctor's prescription, since it is included in the list of over-the-counter drugs. But this does not mean at all that you can self-medicate.

The cost of Gepatrombin G ointment depends on the region of the country and ranges from 165 to 230 rubles.

Despite the high effectiveness of Hepatrombin G in the fight against hemorrhoids, you need to understand that it is unlikely that it will be possible to cure the disease with only one ointment. Remember that defeating hemorrhoids is possible only with the help of complex treatment, which can be prescribed by a competent specialist - a proctologist. Therefore, if you notice the first signs of hemorrhoids, do not self-medicate and do not hesitate to consult a doctor, even if you are ashamed to show him your problem area.

Indications for use

Gepatrombin ointment for hemorrhoids is used primarily, although there are other recommendations for applying the composition. In the case of hemorrhoids, ointment is prescribed for bumps of external and internal localization.

Also in proctology, ointment is prescribed when the following problems are present:

• thrombophlebitis of the veins passing in the rectum;
• predisposition or presence of predisposing factors to the appearance of thrombosis in the rectum;
• eczema in the anus;
• anal fissures;
• anal fistulas;
• the period of preparation for surgery in the anus, especially if inflamed hemorrhoids are present;
• postoperative period of hemorrhoids.

Ointment that is not marked G is used in the following cases:

• inflammation of the veins, which creates a risk of blood clots;
• varicose veins of the legs;
• inflammation of the joint membranes, accompanied by swelling and pain;
• an infiltrate formed due to a poorly executed intramuscular injection, resulting in an accumulation of cellular fluid, blood and lymph in the tissues. In case of a purulent process, treatment requires surgical treatment with cleansing of the cavity and its drainage;
• mastitis - due to the fact that the drug has a strong anti-inflammatory effect;
• boils;
• carbuncles;
• ulcers on the legs caused by impaired blood circulation, which can be observed with atherosclerosis of the leg veins and diabetes mellitus;
• soft tissue injuries, which cause extensive hematomas;
• tenosynovitis;
• inflammation of the skin and soft tissues of a non-infectious nature;
• inflammatory processes in the lymphatic ducts.

Hepatrombin G is not effective when used externally, since its components cannot penetrate the tissues to the proper extent. The drug is designed specifically for the treatment of hemorrhoids and anal problems. In all other cases, hepatrombin is prescribed exclusively without G.

Analogs

Among the most effective analogues of Gepatrombin G in the form of an ointment are:

1. Heparoid is curative. Emulsion for external use. The main active substance is heparinoid. Prescribed for the treatment of mild stages of hemorrhoids, in which there is no bleeding. It has blood thinning properties, relieves swelling and inflammation of the affected area.
2. Heparin ointment. An effective product at an affordable price. It has a combined effect and can be used to treat both external and internal manifestations of hemorrhoids. Reduces pain, improves blood flow and prevents blood clots.
3. Aesculus. A preparation from domestic manufacturers based on horse chestnut extract. Helps strengthen the walls of blood vessels, heal cracks and other damage to the skin and mucous membranes, relieves swelling and improves lymph flow.

The following drugs are considered similar in composition to rectal suppositories:

1. Nigepan. They promote the resorption of blood clots and hemorrhoids, relieve pain, eliminate burning and a number of other manifestations of hemorrhoids that bother the patient.
2. Gepasolone. Prescribed for exacerbation of hemorrhoids, accompanied by severe pain, bleeding, itching and the formation of nodes and anal fissures. Thanks to the main active substances: heparin, lidocaine and prednisolone, they quickly and effectively suppress pain, relieve swelling and inflammation, and prevent the destruction of venous walls.

At the first symptoms of incipient hemorrhoids, doctors strongly recommend seeking help from a clinic in order to prevent the development of complications and to prevent the disease from leading to the need to operate on the patient. It should be remembered that one of the most severe consequences of neglected hemorrhoids can be the degeneration of hemorrhoids into oncological formations.

Hepatrombin G during pregnancy: pros and cons

Hemorrhoids are a common common problem in pregnant women. A decrease in activity, a change in the nature of the diet, hormonal and anatomical changes in a woman’s body lead to the fact that the venous vessels are under stress. As a result, half of women discover hemorrhoids by the end of their pregnancy. Childbirth only complicates the situation: due to pushing, hemorrhoids are observed in 80% of women in labor. Is it possible to protect against Hemorrhoids during pregnancy with Hepatrombin G?

You can use this remedy, but after the third month of pregnancy, on the advice and under the supervision of a doctor

Such caution is justified: hepatrombin contains prednisolone, a hormonal drug that can harm the fetus in the first trimester

But in the later stages, doctors often recommend Hepatrombin G. It is indicated if a woman suffers from chronic hemorrhoids, frequent bleeding, cracks, and inflamed nodes are observed.

Hepatrombin G is a modern and highly effective means of preventing and treating hemorrhoids. The components of the drug “work” in a complex manner, each providing its own effect: anticoagulant, analgesic, sclerosing, anti-inflammatory. Using the drug under medical supervision, you can significantly alleviate your condition. And by using Hepatrombin simultaneously with other means and non-invasive medical procedures, you can avoid surgery.

Use during pregnancy and lactation

Quite often, women first encounter symptoms of varicose hemorrhoidal veins during pregnancy or after childbirth. This pattern is due to a number of objective reasons, including constipation, decreased activity and changes in hormonal levels.

The problem is further complicated by the fact that bearing a child and lactation forces you to be extremely careful when choosing a method of therapy and preferred medications. This also applies to rectal suppositories, which, although they act locally, can harm the health of the mother and baby.

Thus, Gepatrombin G suppositories for internal hemorrhoids are prohibited in the first trimester of pregnancy. It is during these twelve weeks that the organs and systems of the fetus are formed and laid down, and the effects of hormonal components can disrupt the course of natural embryogenesis.

The use of the drug in the second and third trimesters is permitted by the instructions according to the indications. The only, but very important clarification is that the decision to use suppositories is made by the attending doctor after assessing all possible risks.

Anti-hemorrhoid suppositories Gepatrombin G should also be used during lactation after consultation with a specialist and in the permitted dosages.

pharmachologic effect

• The effect of drugs is due to their active components.
• Heparin sodium has an antithrombotic effect (dissolves microthrombi in capillaries), relieves swelling, has an anti-inflammatory effect, improves local blood flow and promotes the restoration of connective tissue.
• Allantoin has regenerative and anti-inflammatory properties, stimulates metabolic processes.
• Dexpanthenol has a dermatoprotective effect, promotes tissue healing, stimulating the processes of granulation and epithelization. Thanks to dexpanthenol, heparin penetrates faster into the upper layers of the skin.

Differences between Gepatrombin and Gepatrombin G

The first difference is the presence of additional components and a different mechanism of action.

Hepatrombin includes not only sodium heparin, but also:

• dexapanthenol;
• allantoin;
• levomenthol;
• disodium edetate;
• carbomer;
• essential oils;
• water.

Due to this combination of components, the drug exhibits wound-healing, regenerating and anti-inflammatory effects. Allantoin and dexapanthenol help heparin to be absorbed into tissues more quickly. The substances stop the inflammatory process and act as catalysts for granulation and epithelialization of tissues.

Hepatrombin G increases the regenerative abilities of connective tissues and prevents blood coagulation at the site of hemorrhoids.

Hepatrombin G consists not only of heparin, but also of prednisolone and lauromacrogol, so the drug exhibits venosclerotic, antithrombotic, antipruritic, local analgesic, anti-edematous and anti-inflammatory effects.

Thanks to this combination, the medication leads to an increase in the regenerative abilities of connective tissues, preventing blood coagulation at the site of hemorrhoids.

Prednisolone is a hormonal component, therefore it has anti-inflammatory, anti-exudative and anti-allergic effects.

Lauromacrogol is characterized by a local anesthetic effect. Thanks to it, hemorrhoids undergo a process of sclerosis.

Gepatrombin G cannot be used for:

• bacterial, viral and fungal infections;
• tuberculosis;
• syphilis;
• tumors of the skin;
• development of reactions to vaccination;
• predisposition to bleeding.

Gepatrombin G is prohibited for use by women during pregnancy up to 14 weeks.

Hepatrombin has 3 release forms - ointment, gel and suppositories for rectal administration.

There are other differences too. Hepatrombin has 3 release forms - ointment, gel and suppositories for rectal administration. Gepatrombin G is sold only in ointments and suppositories.

What is the price

The cost of medications varies. The price of Gepatrombin ointment depends on the number of units of the active substance:

• 500 IU sells for 203 rubles;
• 300 IU for 112 rubles.

Candles 10 pcs. can be purchased for 151 rubles, and the gel for 130 rubles.

Gepatrombin G in suppositories costs 280 rubles, and in ointments - 215 rubles.

Means of similar action

Hepatrombin G is not the only remedy that effectively copes with the manifestations of hemorrhoids. In pharmacies you can purchase an ointment with a similar spectrum of action. For inflammation of hemorrhoids, the following analogues can be used:

• Bezornil is used rectally and externally;
• Heparin ointment is applied externally;
• Hemorol is applied rectally and externally;
• Proctosan – applied externally;
• Relief – applied rectally;
• Ultraproct - applied rectally.

The medicine can be replaced with Bezornil.

• "Betiol";
• "Simetrid";
• "Anuzol";
• "Doloproct";
• "Olesthesin";
• "Bezornil";
• "Ultraproct";
• "Proctophytol";
• "Baliz";
• "Nigepan";
• "Proctosedyl";
• "Glivenol".

Similarities between the compositions of Hepatrombin G and Heparin ointment

Both drugs contain heparin. This component, when applied to the affected area, prevents the formation of blood clots. Shows anti-inflammatory effect.

Heparin is gradually released, which leads to a decrease in the inflammatory process.

Drugs are prescribed for:

• various types of hemorrhoids;
• thrombophlebitis of the veins in the anorectal passage;
• fistulas, eczema and itching in the rectal area.

If the patient has developed hemorrhoids, then it is necessary to use medications 2-3 times a day until acute symptoms disappear.

If the drugs are used incorrectly or for a long time, side symptoms may appear. This process is characterized by:

• hyperemia of the skin, rashes and itching;
• increased platelet levels.

The development of systemic symptoms cannot be ruled out.

If side effects occur, the drugs are discontinued.

Consequences of use and contraindications

Recommended for acute thrombosis, anal fissures and eczema of the anal area. Helps with bleeding hemorrhoids, as well as with external and internal hemorrhoidal cones. Hepatrombin ointment is often prescribed to patients who are undergoing surgery to remove a hemorrhoid and are prescribed treatment after surgery.

Hepatrombin G is recommended for the local treatment of external and internal hemorrhoids, thrombophlebitis of the anal veins, anal fissures, fistulas, eczema and itching in the anal area.

Rectal suppositories are also used in preparing the patient for surgery in the anus and as part of the complex treatment of operated or thrombosed hemorrhoids.

• skin lesions of bacterial, viral, fungal etiology;
• reactions to vaccination;
• syphilis;
• tuberculosis;
• skin tumors;
• tendency to bleed;
• pregnancy (first trimester);
• children under 12 years of age (for rectal suppositories);
• hypersensitivity to the active and auxiliary components of the drug.

Due to the strong effects and content of active substances in the composition, before using Hepatrombin, mandatory consultation with a specialist is necessary.

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Have you consulted a doctor in person about hemorrhoids?

• Fungal, viral and bacterial lesions of the anus.
• Oncological diseases.
• Syphilis.
• Tuberculosis.
• Blood clotting disorders.
• Individual sensitivity to the components of the drug.
• First trimester of pregnancy.

You should also not increase the dosage of the drug. This can lead to a slowdown in regeneration processes, as well as side effects (itching, hives and skin burns).

Use of hepatrombin

In general, treatment of hemorrhoids with Hepatrombin G is well tolerated. However, side effects are possible, manifested in allergic reactions and redness at the site of application of the drug. In this case, you should stop using the medications and consult a doctor.

Long-term treatment and application to large areas may lead to the development of systemic side effects. In some cases, the use of medications is not allowed.

Damage to the anus and rectum by infectious agents. The medications contain prednisolone. This substance is used for inflammatory processes. However, it reduces local immunity, facilitating the spread of pathogenic microorganisms.

Tumor diseases of the affected area. Prednisolone is a hormonal drug that can accelerate tumor growth.

Problems with blood clotting. The main active ingredient in rectal suppositories and ointments is heparin, which thins the blood. With reduced blood clotting, it can cause severe bleeding.

Other contraindications include:

• tuberculosis and syphilis;
• reactions to vaccines;
• I trimester of pregnancy;
• the presence of individual intolerance to the components included in the suppositories or ointments.

  For tuberculosis, it is prohibited to use hepatrombin ointment

Use for other diseases

Gepatrombin ointment may have indications for use other than hemorrhoids.

A drug that prevents the formation of blood clots in blood vessels, with a strong anti-inflammatory effect, can be used in the treatment of many diseases.

Gepatrombin ointment for varicose veins

Method of use: three times a day, Hepatropin G ointment is applied to the legs with massage movements in the direction from bottom to top. It is recommended to wear special compression garments or an elastic bandage.

Multiple cases of use of this drug have confirmed its high effectiveness in the treatment of varicose veins with hepatrombin ointment for legs . "Dissolving"

thrombotic formations in the veins. Swollen, clogged veins, which no longer effectively perform their important functions, undergo sclerosis. This reduces the external, disfiguring symptoms of varicose veins. The condition of veins located close to the surface of the skin improves significantly.

Gepatrombin ointment for bruises

The product has a powerful thrombosis-absorbing effect . Hematomas are just such a physiological phenomenon. Broken small blood vessels lose blood, which then clots. A local thrombotic formation is formed. The blood cells responsible for the gradual destruction of such pathological foci require a long amount of time to complete their work. Heparin, which is part of the ointment, quickly copes with hematomas, speeding up the healing process by half .

Reviews

I have been suffering from chronic hemorrhoids for a long time. Numerous folk remedies provided relief from this problem for a short period. I’m used to putting up with discomfort in the intimate area. I tried hepatrombin ointment. At first the effect was only anesthetic. I thought that this would be the end of the effectiveness of the drug. But no. Gradually I began to notice that I was paying less and less attention to pain and itching. The bumps stopped falling out of the anus. I used this wonderful product for 2 months. I feel like a healthy person!

Pharmacological properties

Pharmacodynamics

The combination of active components of Hepatrombin G provides its antithrombotic, anti-inflammatory and venosclerotic effects when applied topically in proctology.

Pharmacodynamic properties of the active ingredients of the drug:

• heparin: a direct anticoagulant that affects blood clotting factors directly in the vascular bed; as a result of external use, it has a local anti-exudative, antithrombotic and moderate anti-inflammatory effect; improves the regeneration of connective tissue, prevents blood coagulation in hemorrhoids;
• prednisolone: ​​glucocorticosteroid (GCS) with anti-inflammatory, antiexudative and antiallergic action, reducing burning sensation, itching and pain in the anorectal area;
• lauromacrogol 600: venosclerosing agent with local anesthetic effect, promotes the adhesion and healing of hemorrhoids.

Pharmacokinetics

• heparin: when absorbed, it is biotransformed in the liver with the participation of the enzyme hepatic heparinase and partially in the reticuloendothelial system (RES) of macrophages; Up to 95% of the substance binds to plasma proteins; volume of distribution (Vd) increases with increasing dose; Heparin is eliminated by the kidneys, the half-life (T1/2) ranges from an hour to an hour and a half;
• prednisolone: ​​when absorbed, it is biotransformed in the liver; about 1% is eliminated unchanged by the kidneys; the biological T1/2 indicator is from 18 to 36 hours, and T1/2 from plasma is from 115 to 212 minutes.

Reviews, cost and analogues of Gepatrombin ointment

Reviews from doctors about the use of medicine to resolve blood clots are good. The effectiveness is beyond doubt, as patients say. For lasting results, Gepatrombin is used in combination with other medications. The downside is that the drug has no effect on the causes of the disease.

Positive opinions of patients are also associated with the cost of the ointment or gel. Compared to analogues, they are much cheaper. The product can also be used to treat complications of varicose veins - thrombophlebitis, periphlebitis, which is a plus.

There are no complete structural analogues. There is no medicine for leg veins that contains the same combination of active substances. The advisability of using Hepatrombin or its analogues is determined by a phlebologist. Independence in the selection of medications is accompanied by the risk of complications of varicose veins of the legs.

Let's consider several analogues that are similar in action for varicose veins and thrombosis:

Description and composition

The drug has several forms of release intended for the treatment of various diseases. If hemorrhoids are detected, Hepatrombin G is used in the form of rectal cream and suppositories. Regular Hepatrombin is not suitable for this, because it can cause burns to the rectal mucosa. The use of drugs in this group has its own characteristics, so it would be useful to consult a proctologist before treatment.

Composition of the product:

1. Heparin (65 IU/1 gram ointment and 120 IU/1 gram suppository). Direct anticoagulant, prevents the formation of blood clots, promotes tissue healing. It has anti-inflammatory and anti-edematous properties, improves blood circulation and promotes the removal of toxins from tissues.
2. Lauromacrogol (30 mg/1 gram of product). A sclerosing agent that has a mild anesthetic effect.
3. Prednisolone (2.233 mg/1 gram ointment and 1.675 mg/1 gram suppository). Antiallergic and anti-inflammatory component. Relieves pain, itching and swelling of the affected area.

The effectiveness of Hepatrombin G for hemorrhoids has been proven by numerous scientific studies, as well as practical experience in the use of many patients. The drug is usually well tolerated, although there are contraindications for use. In addition, the product is affordable, and together with other treatment methods it can eliminate hemorrhoids even in advanced stages.

Operating principle

After applying “Hepatrombin” to the skin, the process of absorption of heparin into the skin begins, after which the active substance penetrates the blood. Heparin prevents the formation of blood clots. It penetrates slowly into the blood, providing a longer therapeutic effect. After this, the active substance begins to interact with protein compounds. Once in the liver, it is broken down into inactive components, which are excreted from the patient’s body along with urine.

"Gepatrombin" is produced in 2 versions: ointments and gels. The product is contained in hermetic tubes that differ in volume. Among the analogues of the drug, the most effective (as evidenced by reviews) are “Relief”, “Proctosan”, “Ichthyol”, “Anuzol” and “Betiol”. Your doctor will tell you which medication to choose. The effectiveness of each of them is evidenced by reviews on the site.

Possible complications and side effects

The drug is usually well tolerated by patients, so the risk of side effects is minimal. However, if the dosage of the drug is violated, as well as in case of incompatibility of the drug, symptoms such as redness, burning in the anus and anal area, rash and allergic reactions may occur.

Hepatrombin G can cause local side effects: hypersensitivity reactions, skin hyperemia.

As a result of long-term treatment and/or application of ointment to large surfaces of the skin, systemic adverse reactions are possible, for example, swelling, slowing down the processes of crack regeneration.

How do Gepatrombin drugs work for hemorrhoids?

Hepatrombin is used to treat pancreatitis

Hepatrombin for hemorrhoids is intended for the treatment of the following pathological conditions:

• external and internal hemorrhoids;
• thrombophlebitis of hemorrhoidal veins (hemorrhoidal veins are located in the anus and rectum);
• fistulas formed in the anus;
• anal fissures.

Suppositories and ointment for hemorrhoids are used to relieve symptoms of the disease in preparation for surgery in the anus or rectum. They are also used after surgery to remove hemorrhoids for preventive purposes.

Hepatrombin for hemorrhoids

This drug has a combined effect. It is actively used in proctology as a means of dissolving blood clots and preventing their formation. This drug is used for the development of hemorrhoids. It has a direct effect on the source of inflammation and promotes the healing of damaged veins.

The main active ingredient of the drug is heparin - one of the most effective anticoagulants. Heparin not only thins the blood, but also improves the regenerative abilities of connective tissue in the anus and rectum. When applied to hemorrhoidal cones, heparin dissolves the emboli that cause the veins to expand and prevents their further formation.

Prednisolone belongs to the group of glucocorticoid drugs that have a powerful anti-inflammatory and antiallergic effect. By relieving the inflammatory process, prednisolone prevents the release of exudate through dilated vessels. Thanks to this spectrum of action, itching, burning, pain and other unpleasant sensations in the affected area are relieved.

Lauromacrogol has an analgesic effect and promotes the resorption of blood clots.

After application to the affected area, the active substances of the drug are absorbed into the blood, having a systemic effect on the body. They are biotransformed in the liver, almost completely bound to blood proteins, and then excreted in the urine.

Efficacy of the drug

For those who are wondering “will Hepatrombin suppositories help with hemorrhoids?”: a clinical study has been conducted on the effectiveness of the drug.

Results:

1. Use for a week reduces the incidence of bleeding from the anus from 80 to 5%.
2. The pain syndrome subsides or disappears in 95% of patients.
3. The risk of thrombosis is reduced from 54 to 8%.

Ease of use, speed of action, safety of use and high efficiency determine the choice of “Hepatrombin” in the form of suppositories or ointments for the treatment of hemorrhoids.

Which ointment is better? In what cases should you choose one drug or another?

Hepatrombin is an effective remedy for hemorrhoids; thanks to the use of ointments and suppositories, it is possible to quickly eliminate pain, inflammation, and accelerate regeneration processes. Due to the complex effects of heparin, lauromacrogol, and prednisolone, a pronounced therapeutic effect is ensured.

If you carefully study the composition of this medicine, you can determine that Gepatrombin is an anticoagulant. In this regard, certain restrictions in application are introduced. It is not recommended to use the drug for acute or chronic disease. In case of severe bleeding, Hepatrombin is contraindicated, as it reduces the rate of blood clotting.

During the treatment of thrombosed hemorrhoids, anticoagulant properties are a priority, as they help normalize microcirculation in the vessels. This is what contributes to the rapid elimination of the inflammatory process.

Relief and Gepatrombin are drugs that are widely used in proctological practice to eliminate the manifestations of hemorrhoids and quickly heal cracks in the rectum. Each of the medications is highly effective and fully copes with the task of curing hemorrhoids and helps restore the structure of damaged mucous membranes.

The main difference between the drugs is that Gepatrombin should not be used if there are bleeding wounds in the rectum. Relief works differently - it helps increase blood clotting, which helps to quickly eliminate bleeding.

The active ingredients of Relief are shark liver oil and phenylephrine hydrochloride. Like Gepatrombin, it is available in the form of suppositories and ointments, which greatly simplifies the use of the medicine.

But it is worth considering that Relief should be used with caution during pregnancy and lactation. The drug is contraindicated in severe diabetes mellitus, as well as tuberculosis.

It is worth noting that an analogue of Relief ointment - Gepatrombin can be used for fistulas and eczematous rashes in the anus.

The drug Proctosan is recommended for use at the initial stage of pathology development. Unlike Gepatrombin, it contains lidocaine (a strong anesthetic), due to which it has a rapid analgesic effect.

The use of rectal suppositories for hemorrhoids allows you to get rid of severe itching and burning due to the specific properties of bufexamak; it helps to stop the inflammatory process and eliminate local discomfort.

As with the use of Gepatrombin, the use of suppositories and ointments during pregnancy and lactation is not allowed, although the drug is not a steroid hormone.

The use of the drug is possible during the period of exacerbation of the disease, as it promotes rapid healing of cracks and elimination of inflammation.

Proctosan is produced by a domestic pharmaceutical company, the cost of suppositories and ointments is 337-510 rubles.

Nigepan is an analogue of Hepatrombin, it also contains heparin, and complements its action with benzocaine, which is characterized by an analgesic effect.

The use of suppositories is indicated for the treatment of hemorrhoids; the drug has a wound healing effect. Treatment will be quite effective in the presence of anal fissures, severe pain in the case of minor inflammation of the hemorrhoids. The use of the drug is indicated for mild illness.

It is worth noting that it is possible to combine treatment with Nigepan with the use of ointments, for example, Hepatrombin. In this case, the therapeutic effect will be enhanced and inflammation of the skin around the anus will be eliminated.

Thanks to treatment with Nigepan, it is possible to prevent the formation of blood clots, relieve inflammation, as well as swelling.

As in the case of the use of Gepatrombin, it is not recommended to use Nigepan suppositories in the presence of excessive sensitivity to the components or blood clotting disorders. The medicine should not be used by pregnant and lactating women, as well as children under 14 years of age.

If you have an allergic reaction to rectal suppositories, itching and swelling of the mucous membranes in the anus may occur. In case of such manifestations, it is worth stopping their use.

Nigepan is produced only in the form of candles, the cost of packaging varies between 214-358 rubles. The drug can be considered affordable and practically does not cause the development of adverse reactions.

The mechanism of action of tribenoside is based on a decrease in the endothelial pores of the veins, due to which the permeability of blood vessels is reduced, and the release of blood components and fluid directly from the blood rust into the tissue is prevented. As a result, it is possible to completely eliminate swelling, normalize microcirculation, increase the elasticity of the vein walls and strengthen them.

Tribenoside exhibits antiallergic and analgesic properties, as it blocks the synthesis of certain anti-inflammatory substances.

The use of Procto-Glivenol is indicated for both external and internal hemorrhoids. Unlike Gepatrombin, it can be used in the acute period.

Although Procto-Glivenol is characterized by many positive qualities, the use of the drug may be accompanied by the manifestation of undesirable effects, which are mainly associated with intolerance to the components.

As with the use of heparin-based products, local swelling, increased severity of pain, the appearance of urticarial rash, and the development of dermatitis are possible. Quite rarely, bronchospasm occurs, as well as Quincke's edema.

Cost 385-560 rubles, available without a prescription. Compared to Gepatrombin, the drug is expensive, but quite effective.

It is worth noting that the treatment will be much more effective if you additionally take drugs that increase vascular tone and normalize blood circulation. Troxevasin is one of these drugs. It is recommended to take it three times a day; the duration of treatment for hemorrhoids is 30 days.

Levomekol ointment can be used to accelerate the process of skin regeneration. In addition, the drug is characterized by antimicrobial properties and helps eliminate inflammation. Used for hemorrhoids, when there is infection of the mucous membranes with mixed flora.

Alternative for pregnant women

Drugs for the treatment of hemorrhoids during pregnancy are selected according to a completely different principle. Hepatrombin, as well as its analogues, is not recommended for use by an expectant mother. You can replace them with other means, for example, sea buckthorn suppositories, suppositories with papaverine or propolis. The use of heparin ointment and Troxevasin gel is also allowed.

conclusions

Having assessed all the advantages and disadvantages of each drug, it is difficult to determine which one is better, since it is impossible to predict the body’s reaction, everything is individual. If one of the remedies does not work, you will need to switch to another drug.

Treatment should be carried out under the strict supervision of a doctor; it is important to identify negative manifestations in time and take measures to completely stop them. It is worth remembering that following a diet is quite important. Eliminating a number of foods from the diet will help improve your general condition and speed up recovery.

Usually hemorrhoids do not disappear completely, they decrease in size, but if they do not cause discomfort, then this is not a pathology. It is important to control their size and begin treatment at the first manifestation of the inflammatory process. It is in the early stages that hemorrhoids can be cured much faster. Do not self-medicate, be sure to consult a doctor!

• Stagnation of blood, dilation of veins, formation of blood clots are factors that contribute to the occurrence and growth of hemorrhoids.
• Drugs from the group of anticoagulants and venotonics, which normalize the condition of blood vessels, can cope with the problem.
• Among the most popular medications are Hepatrombin and Hepatrombin G for hemorrhoids. These drugs are available in several forms, they are inexpensive, easy to use and quite effective.

Hide content

Gepatrombin and Gepatrombin G are drugs from the group of anticoagulants. Their task is to normalize the functioning of blood vessels, ensure proper blood flow and prevent the formation of blood clots.

1. Hepatrombin is prescribed for varicose veins, venous insufficiency, thrombophlebitis and other vascular pathologies of the lower extremities and pelvis, various injuries, and damage to the skin.

2. Hepatrombin was created exclusively for the treatment of hemorrhoids.

3. Its task is to influence the veins located in the rectal area, to prevent the formation of internal ruptures and anal fissures.

Both drugs come in different forms. Hepatrombin is offered in the form of an ointment or gel, Hepatrombin G is offered in the form of an ointment or rectal suppositories.

The products are sold in pharmacies without a prescription and can be used in combination with any medications: tablets, injections, compresses.

Read on our website about other effective drugs for the treatment of hemorrhoids, available in the form:

• ointments: Vishnevsky, Fleming, heparin, Bepanten, Levomekol, methyluracil, ichthyol, zinc, Aurobin, Bezornil;
• gel: Troxerutin, Lyoton.

The drugs are successfully used for external, internal or combined hemorrhoids. When used correctly they can:

• prevent the development of blood clots;
• reduce blood viscosity;
• improve blood flow;
• activate lymph outflow;
• relieve external and internal swelling;
• prevent inflammation;
• relieve pain and itching in the anal area;
• speed up wound healing.

Gels, ointments and rectal suppositories can be used for both treatment and prevention.

They are indicated for people at risk, prone to increased blood viscosity or men with hereditary fragility of blood vessels. The drugs are effective for preparation for surgery or recovery after resection of hemorrhoids.

Composition of the drug

• Gepatrombin gel and ointment are packaged in 40 g aluminum tubes.

• The tubes are packed in cardboard boxes and supplied with instructions.
• The gel is transparent and colorless, has a light consistency and a characteristic “pharmacy” smell.
• Hepatrombin ointment for hemorrhoids is white, denser and more uniform, the smell is similar.
• As active ingredients, both drugs contain:

1. Heparin. An anticoagulant that normalizes blood flow and prevents thrombus formation.
2. Allantoin. Prevents the development of inflammation, disinfects, accelerates the healing of cracks, and promotes rapid tissue regeneration.
3. Dexpanenol. A potent wound healing and restorative agent that improves the effect of heparin.

Use during pregnancy

Doctors do not recommend using Hepatrombin G during the first three months of pregnancy, since the drug contains the hormone prednisolone, which can have undesirable effects on the development of the child. Starting from the 4th month, the use of the medicine is considered possible only with constant monitoring by a specialist. The same applies to the period of breastfeeding.

Is there a difference between these drugs and what?

The ointments have some similarities:

• both have a combined composition and several active components,
• both contain sodium heparin and an anesthetic,
• have antithrombotic, decongestant and analgesic effects, reduce inflammation,
• Indications for both include external hemorrhoids,
• Contraindications include allergic reactions to the active ingredients.

However, there are much more differences between these means:

• They contain heparin in different dosages, Heparin ointment has 100 IU, and Hepatrombin has 65 IU.
• The antithrombotic effect of treatment with Heparin ointment is better expressed.
• Hepatrombin has an antiallergic and stronger anti-inflammatory effect due to the presence of Prednisolone in the composition.
• The analgesic effect develops better and faster with Heparin ointment, since it contains Benzocaine.
• Gepatrombin has more indications specifically for proctological practice - in addition to external hemorrhoids, these are internal hemorrhoids, thrombophlebitis of the rectal veins, fistulas and fissures of the anus, as well as itching and allergic reactions in the anus.
• Heparin ointment has a wider scope of application in general, but in proctology it is prescribed for the treatment of external hemorrhoids and thrombophlebitis.
• Heparin ointment has a minimum of contraindications - childhood, impaired skin integrity, ulcers and bleeding. Hepatrombin has many additional contraindications - decompensated heart failure, endo- and myocarditis, lung diseases, diabetes mellitus, bronchial asthma, cancer, decreased blood clotting, bleeding, specific and nonspecific infectious pathologies.
• The cost of a package of Heparin ointment is almost 10 times cheaper than Hepatrombin.

Proctoglivenol and Gepatrombin G have some similarities:

• both medications are indicated for the treatment of external and internal hemorrhoids, as well as for the severe accompanying pain syndrome;
• produced in candle format;
• both contain a substance that causes an analgesic effect;
• both drugs also have an anti-inflammatory component;
• both are contraindicated in case of allergies to their components, pregnancy;
• The regimen is similar. Gepatrombin G and Proctoglivenol can be used twice a day as much as possible.

However, there are much more differences between these means:

• Proctoglivenol contains Tribenoside, which has an angioprotective and anti-edematous effect; Gepatrombin G does not contain it.
• But Gepatrombin G contains Heparin and Prednisolone, which have antithrombotic and anti-inflammatory effects, respectively, which are not found in Proctoglivenol. It is they who give this medicine a wider list of diseases for which it is prescribed.
• Indications for the use of Hepatrombin G include thrombophlebitis of hemorrhoidal veins, fissures and fistulas of the anus. Proctoglivenol does not have any.
• Hepatrombin G does not have an angioprotective effect; it does not strengthen the walls of blood vessels and does not normalize their tone.
• Proctoglivenol has contraindications for liver failure, which Gepatrombin G does not have.
• But Hepatrombin G additionally has contraindications: decompensated heart failure, endo- and myocarditis, lung diseases, diabetes mellitus, bronchial asthma, cancer, decreased blood clotting, bleeding, specific and nonspecific infectious pathologies.

General information

Both drugs have identical effects. They reduce blood viscosity, dissolving emboli, preventing their further formation.

The only difference is that Hepatrombin can be used to treat dilated veins that are located on the body. Hepatrombin G is intended for the treatment of veins located in a delicate area - the anus.

However, their spectrum of action is similar. Both types have the following medicinal qualities:

• improve blood flow by reducing its viscosity;
• prevent the formation of emboli;
• dissolve existing blood clots;
• eliminate swelling and relieve inflammation.

Regular Hepatrombin ointment cannot be used to treat hemorrhoids, as it can cause a burn of the mucous membrane of the affected area, thereby intensifying the course of the disease.

In the treatment of hemorrhoids, specialized drugs are used - rectal suppositories and Gepatrombin G ointment. This drug is one of the combined drugs of local action. Gepatrombin G has a pronounced anticoagulant effect, relieves itching and allergic manifestations. This product promotes the formation of new cells, accelerating the healing process of damaged tissue.

Undesirable effects of the drug

Reviews from patients and clinical observations of patients indicate that adverse reactions to the use of Gepatrombin suppositories occur extremely rarely. But in some cases, immediately after their administration, redness of the skin of the anus was observed.

The second most common side effect of the drug is an allergy to its ingredients, which is expressed by local reactions such as itching, burning, hyperemia and swelling of the tissues of the anorectal area. Urticarial rash and dermatitis may also appear. Systemic allergic reactions were not observed.

Features of therapy

Before using ointment or suppositories, you must wash the anus area without soap and then dry it with a clean towel. The ointment is applied in a thin layer to the damaged areas several times a day until the signs of the disease completely disappear. After eliminating severe symptoms, the number of applications is reduced to 1 time, which allows you to consolidate the achieved result.

For internal hemorrhoids, the ointment is used rectally. It is administered using a tip inserted into the rectum. The product is squeezed out by applying light pressure on the tube.

Suppositories are inserted into the rectum 1-2 times a day after bowel movements and hygiene procedures.

Before carrying out the treatment procedure, you must first empty your intestines.

1. Empty the rectum and perform anal hygiene.
2. Apply a thin layer of cream to the hemorrhoidal cones located outside.
3. Repeat the procedure 2-4 times a day.
4. As the symptoms subside, the gel is used for another week, treating problem areas with it once a day.

The cream is also used for internal hemorrhoids. To do this, fix the tip on the tube and insert it into the anus, apply light pressure, squeezing out a small amount of gel. The course of treatment depends on the severity of the symptoms and characteristics of the patient’s body, but usually 14 days are enough for complete recovery.

Ointment analogues

Reviews about Gepatrombin gel are almost all positive. There are literally only a few negative reviews. This situation is due to the fact that Gepatrombin gel has an excellent therapeutic effect, quickly relieving leg fatigue, preventing and reducing swelling, and

. In addition, according to reviews of people who use Gepatrombin gel, the drug effectively stops the further progression of vein diseases. The main factor on the basis of which Gepatrombin gel received a huge number of positive reviews is that it perfectly replaces expensive

, in no way inferior to it in efficiency, but significantly lower in cost.

Positive reviews about Gepatrombin gel were left not only by people suffering from venous diseases, but also by those who have frequent and constant problems with bruising. Hepatrombin literally eliminates even pronounced, large-area and literally black bruises within 2–3 days.

People consider a certain negative quality of Gepatrombin gel to be its specific smell, the inability to use during pregnancy and the relatively long time for complete absorption, which is 5 – 10 minutes. However, these disadvantages are not decisive, as a result of which people still consider the drug to be good and leave positive reviews about it.

Reviews of Gepatrombin ointment for external use are somewhat worse, since among them negative ones are more common, but positive ones still predominate. The greater number of negative reviews about Gepatrombin ointment compared to the gel is due to the dense consistency of the ointment and the relatively long period of its absorption into the skin, which reduces the ease of use of the drug. Since the gel is more convenient to apply, and the therapeutic effect of it and the ointment is practically the same, people prefer the gel.

It is a mistake to believe that these seemingly similar drugs have the same effect, since they even differ in composition.

The use of hepatrombin ointment, which does not have the letter “G” in its name, is indicated for varicose veins, thrombosis, trophic ulcers, mastitis, boils, and sports injuries. While the drug Hepatrombin G is more intended for the treatment of hemorrhoids.

Before going to the pharmacy for this popular remedy, you need to consult with a specialist to find out whether conservative treatment of hemorrhoids will help the patient or whether in his case you need to resort to surgical intervention.

To enhance the effect of Gepatrombin G ointment for hemorrhoids, it is necessary to use it wisely, be sure to follow a diet, lead a healthy lifestyle, etc.

Remember that self-medication can be dangerous. If the ointment helped one person, it does not mean that it will help another. This is not a panacea. And failure to consult a specialist for qualified help in a timely manner only worsens the course of the disease and makes the prognosis less optimistic.

The method of application includes a number of actions:

• Before using the product, you need to carry out water procedures: rinse the problem area with warm water, pat dry with a towel (do not wipe, so as not to cause irritation).
• Apply the ointment to the anus 2 to 4 times a day in a thin layer. Gently rub the product with a clean hand, also touching the skin around the affected area.
• After the pain disappears, you need to reduce the frequency of use of the ointment - it should be applied once a day for 1 week.
• To administer the drug into the rectum, you need to use a tip. You need to screw it to the tube, insert it into the rectum, lightly press the container and squeeze out a little medicine.

After applying the product, it is recommended to lie on your stomach for a while, without covering your buttocks, so that the ointment is absorbed and not rubbed off by your underwear.

In case of severe inflammation and pain, it is allowed to apply the ointment to a cotton sponge and then apply it to the sore spot.

Do not exceed the dosage and frequency of use of the drug, as this can lead to inhibition of the healing process, as well as a slowdown in the rate of absorption of the active components of the drug.

There are no drugs similar in composition to Gepatrombin G ointment for hemorrhoids. But there are ointments and gels that contain the same active ingredients, for example:

• Hepatrombin. The active ingredient in it is heparin, as well as dexpanthenol, allantoin. Medicine is prescribed to prevent thrombosis;
• Venitan forte. The active substance is heparin, as well as horse chestnut seed extract. Used only for external hemorrhoids;
• heparin ointment. Also used for external hemorrhoids. Reduces pain and inflammation, but does not glue damaged vessels;
• Gepasolone. Suppositories are used for internal hemorrhoids. The composition contains heparin, lidocaine, prednisolone.

Hepatrombin G is the only drug of its kind that has a complex effect. There are many substitutes for this drug, but their composition is different. For example, Hemoral suppositories, Procto-Glivenol cream, etc.

The cost of Gepatrombin G ointment in Russia averages 250 rubles per tube weighing 40 grams. At the same time, Procto-Glivenol ointment costs 450 rubles per 30 grams, which is almost 2 times more expensive. The cost of Gepatrombin gel is slightly lower - 180 rubles, however, the effectiveness of this drug is lower, judging by patient reviews.

Side effects and contraindications

Statistics indicate good tolerability of all forms of Gepatrombin. Compliance with the doctor's prescriptions and recommended doses eliminates any unwanted reactions.

When using drugs, allergic reactions of various kinds are possible - hives, rash, swelling, etc.

But with independent and uncontrolled use, complaints were recorded about:

• redness on the skin at the site of application of the ointment;
• rashes like urticaria;
• hypersensitivity reactions to components;
• bleeding of nodes with prolonged use;
• itching and swelling;
• local hemorrhage (bleeding);
• slowing down the healing of wounds and cracks.

After stopping the drug, all unpleasant symptoms usually go away on their own. Prolonged discomfort requires consulting a doctor and selecting another remedy. Accidental ingestion of the ointment is treated by gastric lavage in a hospital setting.

Gepatrombin ointment and suppositories for hemorrhoids have a number of important contraindications. Strict prohibitions include:

• allergy to active or auxiliary substances;
• pathological disorders of blood coagulation function;
• cutaneous syphilis and tuberculosis;
• bleeding wounds of the anal area;
• first trimester of pregnancy;
• malignant neoplasms of the anorectal zone.

Drug analogues and prices

In pharmacies there are many remedies for varicose veins, Russian and foreign. They also have anti-inflammatory, anticoagulant and analgesic effects.

The most popular analogues of Gepatrombin:

• Venolife;
• Heparin ointment;
• Lyoton 1000;
• Troxevasin gel;
• Dolobene.

The price of Gepatrombin ranges from 150-250 rubles per package. The volume of one tube is 40 g.

Numerous reviews of the use of Gepatrombin gel and ointment for varicose veins confirm the effectiveness of the drug. Doctors indicate that the remedy will be most effective in the fight against the initial stage of varicose veins.

The doctor prescribed Gepatrombin for the treatment of varicose veins. I had vascular network for a long time, my legs were constantly buzzing at the end of the working day. After starting treatment it became a little easier. The swelling subsided, the inflammation went away after 2 weeks of using the product. Yes, the visible capillaries will not go away, but I hope that they will not stand out even more and grow. I am satisfied with the product and will use it to prevent vein diseases.

Alla, 44 years old, Kazan

A few years ago, a small lump appeared on my leg, which turned out to be a blood clot. On the doctor's advice, I used Gepatrombin ointment. I applied compresses every day to quickly get rid of this tumor. After just 3 weeks, the lump began to shrink and the blood clot dissolved. There were no side effects, although allergies to ointments are common.

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Igor, 58 years old, Chelyabinsk

The drug Gepatrombin improves blood microcirculation and relieves congestion. It is often used to treat varicose veins, thrombosis and thrombophlebitis, to eliminate trophic ulcers and subcutaneous hematomas. The action of the medicine is based on the substance heparin. It thins the blood and prevents it from clotting. Therefore, the product should not be applied to open wounds. Before using the medication, it is recommended to consult a doctor and study the list of possible contraindications.