Oral contraceptives have become in great demand. Contraceptive drugs Jess or Jess Plus, manufactured by the German pharmaceutical company Bayer, are in demand among women.
Medicines are analogues of each other. The main difference is the presence in one of them of an additional component that has a significant effect on the female body.
Oral contraceptives have become in great demand; Jess or Jess Plus are popular among them.
Drug Jess
Manufacturers can offer a wide selection of hormonal drugs, the main function of which is contraception.
Of course, it’s quite difficult to find something you need the first time:
- Firstly, this can be explained by the fact that hormonal drugs have their own characteristics . Not every woman will be able to positively perceive a hormonal drug and get the desired effect.
- Secondly, many ladies worry about sudden changes in body weight and this is also important. Of course, all hormonal drugs can cause a completely unexpected reaction in the body - this could be nausea, diarrhea, dizziness and lack of strength, as well as loss of performance.
Perhaps one of the most famous contraceptive drugs released today is Jess . This drug is familiar to many women faced with the choice of contraceptive drugs.
As you know, the drug Jess has quite a few analogues, differing in price category, as well as in manufacturer. What is this drug?
Jess represents a single-phase type of contraceptive, one of the microdosed drugs. This drug is classified as a modern generation drug.
Why can this particular contraceptive achieve the desired result? This is explained, first of all, by the fact that the medicine contains a microscopic content of hormones. The big advantage is that while taking Jess, the lady does not have to worry about the side effects inherent in such medications.
Compound
Analyzing the composition of the Jess contraceptive, it should be noted that the basis of the drug is the active substance, which is responsible for the most important function - to protect a woman from unwanted pregnancy.
When taking the pill, the first thing that changes is the cervix, and the process of suppressing ovulation also begins.
Thus, thanks to these functions, a woman does not have to worry about an unwanted pregnancy.
The active ingredients in the drug Jess are ethinyl estradio and drospirenone.
In terms of content volume, drospirenone significantly exceeds the content of ethinyl estradio. As with all medicines, in addition to the active components, there are also auxiliary ones.
They create a “substrate” for high activity components. Thanks to the combination of these components, the drug is tolerated quite easily and does not cause discomfort or side effects when consumed, which is important when taking the drug.
The auxiliary components, as in all medicines, are corn starch, lactose and cellulose.
Analogs
The analogues closest in their effect to Jess Plus are the drug Yarina, which contains the same gestagen, but includes a little more estrogen and microdosed drugs, for example, Logest, Microdinon and Novinet. For the listed medications, the dosage of estrogen is absolutely the same, but the progestogen ingredient is slightly different.
Drug Jess Plus
Often, pharmacists ask women which drug is needed: Jess or Jess Plus? What is the difference and why are these drugs often compared?
Jess Plus is a combination type drug.
This is a contraceptive containing the following components:
- estrogen;
- gestagen;
- calcium levomefolate.
Jess Plus consists of such components .
In the same way as the drug Jess, the contraceptive is taken to prevent unwanted pregnancy.
Compound
The composition of Jess Plus is filled with an active substance in the form of a component such as ethinyl estradiol , which can suppress the period of ovulation, during which, as is known, a woman has a high probability of conceiving a child. As you can see, the composition is identical to the Jess contraceptive.
The composition contains auxiliary components in the form of a vitamin complex. Vitamins play a supporting role and have a beneficial effect on a woman’s health, which is important when taking a contraceptive.
Compound
One tablet of COC Jess Plus contains the following active ingredients:
- Drospirenone (drospirenonum) – 3 mcg; has an antiandrogenic effect.
- Ethinyl estradiol (aethinyloestradiolum) – 20 mcg; analogue of endogenous estradiol.
- Calcium levomefolate (calcii levomefolinas) – 451 mcg; biologically active folic acid formula. This is a medicinal substance designed to eliminate folate deficiency in the female body. The presence of this component in the composition is what distinguishes Jess Plus from Jess.
In total, the blister contains 28 tablets (24 active + vitamins and 4 just vitamins).
Excipients:
- lactose monohydrate - 45.329 mg
- microcrystalline cellulose - 24.8 mg
- croscarmellose sodium - 3.2 mg
- hyprolose (5 cP) – 1.6 mg
- magnesium stearate – 1.6 mg
Action Jess Plus
- Suppress ovulation, i.e. interfere with the development and release of the egg
- Makes cervical mucus thick, making the cervix impassable for sperm
- They change the structure of the endometrium (the mucous membrane of the uterus), as a result - the fertilized egg cannot attach to the walls of the uterus
- Replenishes the lack of folate in a woman’s body
Each package of Jess Plus includes a detailed annotation.
What is the difference between Jess and Jess+?
The difference between Jess and Jess Plus lies in the components that fill the composition of the drugs.
To be more precise, the Jess Plus contraceptive contains a component such as calcium levomefolate, while the Jess drug does not have such a component.
First of all, it should be noted that such a component plays a rather important role primarily for the woman.
The function of the component is to prevent the development of chromosomal abnormalities in the fetus, if the woman still plans to become pregnant.
This is quite important for the future baby and the manufacturer took care of this in advance.
If we take into account the age factor, then, of course, for those who are planning to conceive a baby in the near future, it is better to choose Jess Plus.
Actually, this is the difference between the Jess Plus contraceptive and Jess.
The choice of drug should be made taking into account individual preferences and plans for the future. After all, hormonal drugs can have a serious impact on a woman’s health, including reproductive function. Before choosing a contraceptive, you need to carefully study the composition, as well as find out which components have an impact on health directly in the reproductive sphere.
Hormone therapy as the most effective method of contraception
With the passage of time and the active development of medicine, people increasingly began to resort to hormonal methods of contraception. Note that taking oral contraceptives is suitable for couples who have been together for a long time, and the issue of protection from sexually transmitted diseases is not so relevant. Hormonal contraceptives are in turn divided into “mini-pills” and combined oral contraceptives (COCs).
Today we will talk about the most popular and highly effective drugs based on several components: estrogen and progestogen. Why exactly such drugs have conquered the market? The answer is quite simple - this is an innovative product containing microdoses of active hormone substances that have minimal effect on the female body.
One of the most widely used COCs is Jess Plus. This drug is often prescribed to nulliparous girls due to its gentle effect on health. It contains drospirenone, ethinyl estradiol and calcium levomefolate. The last component is an analogue of folic acid, so it is better absorbed by the body.
Progestogen increases the level of cervical mucus, forming a plug in the cervical canal, thereby preventing sperm from entering the cervix. The movement of sperm through the fallopian tubes is difficult. Drospirenone has a progestational and antiandrogenic function. Estradiol replenishes the lack of estrogen, which regulates many metabolic processes in the body, in particular affecting the regularity of the cycle in women.
The action of drospirenone, due to certain properties, has a number of useful side effects:
- Improves skin condition;
- Reduces swelling;
- Practiced in the treatment of acne;
- Qualitatively affects the condition of hair and nails.
A common reason for prescribing Jess Plus birth control pills is planned pregnancy. This contraception gives a woman’s reproductive system a “rest.” After stopping the pills, renewal and regeneration of the genital organs occurs and the body is ready for its direct responsibilities with renewed vigor.
Some women simply feel comfortable when taking oral contraceptives, since menstruation when taking Jess Plus becomes scanty and painless and causes less discomfort. Another reason to take COCs is to reduce the risk of ectopic pregnancy.
Indications for use of Jess and Jess+
As is already known, both Jess and Jess Plus are contraceptive drugs. The main function of such medications is to protect partners from unwanted pregnancy. Of course, this is one type of contraception and indications for use - protection of a couple during sexual intercourse.
These drugs are prescribed for problems such as:
- Acne. As you know, rashes of various kinds on the face can develop very actively and sometimes have to be fought only with the use of hormonal drugs;
- PMS . Perhaps every woman has at least once encountered increased irritability, as well as other symptoms inherent in the premenstrual period.
At this time, a woman needs to find peace and hormonal medications will help cope with this.
In most cases, hormonal drugs are contraceptives and are intended not only for contraception, but also for treating acne and mitigating the period of PMS.
Indications
“Jess Plus” are hormonal tablets that are indicated for those girls who suffer from hormone-dependent fluid retention. This happens to many people, by the way. They are also great for treating moderate acne. If a girl has folate deficiency, these tablets are also created for her. And they are also indispensable if a woman suffers from a severe form of premenstrual syndrome. And finally, the most important and, in fact, the main effect, as well as a part-time indication, is contraception. In this regard, “Jess Plus” is one of the most reliable drugs in the whole world.
Contraindications
There are many contraindications for such drugs:
- thrombosis of venous or arterial type;
- syndromes preceding thrombosis;
- migraine;
- diagnosis of diabetes mellitus, aggravated by vascular type symptoms;
- at the slightest risk of arterial and venous thrombosis;
- pancreatitis;
- diseases associated with liver dysfunction;
- malignant tumors in the liver;
- neoplasms dependent on a woman’s hormonal levels;
- increased sensitivity to the components of the drug;
- lactation period;
- signs of pregnancy (even not confirmed);
- with uncertain vaginal discharge.
As you can see, there are quite a lot of restrictions on taking medications. If there is at least one of the above points, then it is better not to risk it and consult a doctor about taking this type of contraceptive.
Taking Jess: taking missed pills
Skipping inactive tablets can be ignored. However, they should be thrown away to avoid accidentally prolonging the period of taking inactive tablets. The following recommendations apply only to skipping active pills: if the delay in taking the drug is less than 12 hours, contraceptive protection is not reduced. A woman should take the missed pill as soon as possible and take the next pill at the usual time.
If the delay in taking the pills is more than 12 hours, contraceptive protection may be reduced. The more pills you skip, and the closer the missed pills are to the inactive pill phase, the higher the chance of pregnancy. In this case, you can be guided by the following two basic rules:
• taking the drug should never be interrupted for more than 4 days;
• to achieve adequate suppression of the hypothalamic-pituitary-ovarian axis, 7 days of continuous tablet use are required.
If you are more than 12 hours late in taking active tablets (the interval from the moment you took the last active tablet is more than 36 hours), remember the following.
From the 1st to the 7th day. You should take the last missed tablet as soon as you remember, even if this means taking two tablets at the same time. Continue to take the next tablets at your usual time. But over the next seven days, additionally use a barrier method of contraception. If sexual intercourse took place within 7 days before missing a pill, consider the possibility of pregnancy.
From the 8th to the 14th day. Take the last missed pill as soon as you remember, even if this means taking two pills at the same time. Continue to take the next tablets at your usual time. Provided that you have taken your tablets correctly for the 7 days preceding the first missed tablet, there is no need to use additional contraceptive measures. Otherwise, or if you miss two or more tablets, you must additionally use barrier methods of contraception for 7 days;
From the 15th to the 24th day. The risk of reduced reliability is inevitable due to the approaching phase of taking inactive tablets. Strictly adhere to one of two options. However, if in the 7 days preceding the first missed pill, all pills were taken correctly, there is no need to use additional contraceptive methods. Otherwise, use the first of the following regimens and additionally a barrier method of contraception for 7 days.
1. Take the last missed tablet as soon as you remember (even if this means taking two tablets at the same time). The following tablets are taken at the usual time until the active tablets in the pack are gone. The four inactive tablets should be discarded and the next pack of tablets should be started immediately. Withdrawal bleeding is unlikely until the active tablets in the second pack are gone, but spotting and breakthrough bleeding may occur while taking the tablets.
2.You can also stop taking the tablets from the current pack. Then you should take a break of no more than 4 days, including days you missed pills, and then start taking the drug from a new package.
If you missed active tablets and no withdrawal bleeding occurred while taking inactive tablets, pregnancy must be ruled out.
Side effects
Many hormonal drugs have a number of side effects, from which, unfortunately, many women suffer.
Has the following side effects:
- vomit;
- menstrual irregularities;
- bleeding from the vagina;
- pain in the mammary glands.
However, the list does not end there and occurs in rare cases:
- thromboembolism, manifested both arterial and venous.
It occurs extremely rarely:
- neoplasms;
- hypertension;
- liver dysfunction;
- symptoms of high sensitivity.
Types and characteristics of side effects that occur when taking Jess
Jess is a low-dose hormonal drug prescribed even to young girls under 30 years of age and women who have not given birth, since it has a narrow range of side effects, as well as a low frequency of their occurrence.
Side effects of Jess include:
- the possibility of engorgement of the mammary glands during the first three months of using the drug. These complaints usually go away as soon as the body fully adapts to the new hormonal levels;
- spotting, both in the middle of the cycle and a few days before the expected menstruation. As a rule, the discharge stops within the first few months of use. If this does not happen, it is imperative to consult a gynecologist and replace the drug used with a stronger analogue;
- increase or decrease in body weight;
- increase in blood clotting rates.
In addition, in rare cases, headaches, mood swings, decreased libido, nausea, or disruption of the gastrointestinal tract as a whole are possible.
A significant side effect that occurs in isolated cases is breakthrough bleeding, which is due to the fact that the uterus does not sense the usual hormonal surges. If such a problem occurs, you must immediately stop taking the drug and seek help from the nearest medical facility.
Instructions for use Jess and Jess+
Each drug has instructions for use:
- You need to drink Jess at the same time every day , thoroughly washing it down with water.
- Jess should be taken daily for twenty-eight days.
- Taking the contraceptive from a new package should begin the day after the last pill from the previous package was taken.
- After stopping the drug, bleeding may begin on the second or third day. There is no need to be afraid of this. This is normal.
- It should also be noted that if a woman did not take contraceptives in the previous month , then it is best to start taking Jess from the second to fifth day of the cycle.
However, in parallel it is required to use barrier contraception as a supplement. It is also necessary not to skip contraceptives while taking medications. In the event of a violation, it will be quite difficult to restore the consumption pattern in the future.
As for taking Jess Plus, you must adhere to the same rules as when taking the contraceptive Jess.
Method of administration
- The contraceptive must be taken strictly at the same time every day for twenty-eight days.
- The medicine must be taken with clean water in a small volume.
- It is prohibited to skip taking pills due to difficulties in restoring the consumption regimen.
- If you have not previously taken any contraceptives, you can start taking Jess from the first day of your cycle.
Dosage
The dosage of the drug is universal for everyone - one tablet daily for twenty-eight days.
Overdose
As such, no cases of overdose have been recorded, however, in rare cases, vomiting, weakness and the appearance of spotting may be caused.
Interaction with other drugs
- When the drug interacts with other drugs, the reliability and effectiveness of the drug is lost, and bleeding is also possible.
- In addition, increased clearance of sex hormones may be caused.
- When interacting with antibiotics, enterohepatic circulation cannot be ruled out. Taking Jess can have a significant impact on the metabolism of other medications consumed simultaneously.
To determine the interaction of other drugs with Jess, you need to study the instructions for the drug.
special instructions
In addition to contraindications, there are special instructions that must be studied and followed.
Childhood
The drug is not prescribed to patients under 18 years of age. This is due to its negative effect on the body.
In case of emergency, the drug is used in the treatment of amenorrhea and dysmenorrhea in teenage girls. The appointment is made only by the doctor.
Pregnancy and lactation
The medication must be discontinued immediately after the woman notices the first signs of pregnancy. You should stop not only taking birth control pills, but also other medications before visiting a gynecologist.
When breastfeeding, the medication is not prescribed because it penetrates into breast milk, reduces its quantity and impairs its quality.
Climax
When consumed during menopause, a woman can gain significant weight, especially if she is prone to excess weight.
If the patient plans to abruptly stop taking the medicine, spotting, headaches, and surges in blood pressure may occur. Admission and withdrawal during menopause should be agreed with a specialist.
Alcohol and smoking
Studies have shown that alcohol and nicotine in combination with COCs cause irreparable harm to health, increasing the risk of developing breast cancer, uterine fibroids and endometriosis.
It is strongly recommended to give up alcohol and cigarettes while using contraceptive medications.
Other medicines
Some medications can weaken the effect of contraceptives, provoke a delay in menstruation or unplanned pregnancy due to reduced effectiveness.
You should not combine Jess with the following medications:
- antibiotics from the group of penicillins, tetracyclines and cephalosporins;
- barbiturates;
- antacids;
- enterosorbents.
If it is necessary to use such medications, barrier contraception should be used throughout the course.
Liver and kidney failure
If renal or liver failure is diagnosed, the drug is not used because it cannot be fully absorbed into the body and provide a therapeutic effect.
In addition, the medicine can worsen the course of pathologies and provoke complications.
Terms of sale
As you know, the sale of medicines is now under special control, and getting any medicine without a prescription is quite difficult and, to be more precise, impossible.
As for purchasing contraceptives Jess, I must say that you can buy such a hormonal drug only with a prescription.
Therefore, if you have decided on this method of contraception, then you cannot do without the help of a doctor.
It is necessary to visit a doctor, consult with him and obtain an appropriate prescription in order to purchase a contraceptive.
When choosing contraceptives, take into account your individual health characteristics.
Drug interactions
If, simultaneously with the specified contraceptive, a girl takes drugs that induce microsomal liver enzymes, then it is necessary to use additional contraceptive measures - they should be used for the entire period of using Jess Plus. These drugs include barbiturates, phenytoin, and topiramate.
Another interaction is represented by the following provisions:
- HIV or hepatitis C protease inhibitors may increase or decrease the concentration of hormones in the blood plasma;
- some substances, for example, methotrexate, sulfasalazine, can reduce the concentration of levomefolate calcium in the blood;
- antifungal drugs from the azole group, as well as antibiotics from the macrolide group, reduce the clearance of the contraceptive.
These factors must be taken into account if a woman simultaneously takes Jess Plus and uses other medications to treat other diseases.
Compatibility of Jess Plus and alcohol
Alcoholic drinks have a strong effect on the liver, forcing it to work intensively. At this moment, the hormones that enter the bloodstream with the contraceptive are also affected. The concentration of hormones in the drug decreases, the woman remains unprotected from pregnancy.
If you cannot give up alcohol, you should choose a quality product and a moderate dosage.
Reviews
Women evaluate contraceptives positively, although there are also negative reviews about the Jess contraceptive pills from those for whom this hormonal drug was not suitable.
As a result, hormonal pills provoked side effects, in particular nausea, malaise, headaches, etc. In this case, doctors selected another, more suitable drug.
Reviews of Jess also indicate that the drug helps get rid of acne and improve the condition of the skin. After discontinuation of the contraceptive, the body’s condition does not worsen, so most women respond positively to these pills.
Reviews from doctors are positive, as experts note the effectiveness of Jess tablets, as well as their overall positive effect on the body.
pharmachologic effect
Now we will look at how the drug “Jess” (tablets) works. The instructions tell us that the contraceptive effect is achieved due to many factors. The most important of them are inhibition of ovulation and changes in the viscosity of cervical mucus. As a result, we observe two important processes: it is much more difficult for sperm to reach the egg due to the viscous mucus, but even if this happens, the endometrium of the uterus remains unprepared for implantation of the egg. Even if fertilized, it will be destroyed in the uterine cavity.
What else good does Jess (tablets) promise us? The instructions emphasize that it is drospirenone in this drug that prevents weight gain and other symptoms associated with fluid retention in the body. In addition, it has a positive effect on the course of PMS, usually minimizing it. As a result of regular use of the drug, periods become shorter and lighter. This serves to prevent anemia. Painful sensations decrease or completely disappear.
Why are periods delayed when using Jess?
There may be delays when taking Jess. This is usually due to the onset of menstruation. It is worth noting that the effectiveness of the medication can be reduced by:
- different times of taking the medicine;
- presence of problems with the digestive system;
- other medications taken.
This video talks about the features of restoring the cycle after taking OK:
If there is a delay while taking a contraceptive, the first thing to do is take a pregnancy test.
Advantages of Jess tablets over other contraceptives
The main advantage of the drug Jess is that it provides a very high contraceptive effect, but only when used correctly. If the rules of use are violated, the effectiveness of the product may decrease. In addition, the drug has the following positive effects:
- normalizes the menstrual cycle;
- reduces the intensity of bleeding;
- reduces pain during menstruation;
- improves well-being during PMS:
- regulates the secretion of the sebaceous glands, thereby reducing the oiliness of hair and skin, helping in the fight against acne;
- reduces the risk of tumor diseases of the female genital area;
- reduces the likelihood of atherosclerosis;
- stabilizes the emotional background.
Active ingredients
This is a low-dose, monophasic, oral combination drug. The main active ingredient is estrogen, contained in a minimum dose of 20 mcg per day. The second active ingredient is the progestogen drospirenone. Its composition is identical to natural progesterone and is contained in an amount of 3 mg.
This composition was not chosen by chance. It minimizes possible complications in the functioning of the cardiovascular system and usually does not make negative changes in the general condition of the woman. Most women highly praise Jess pills. Reviews emphasize good tolerability, no side effects, and sometimes even improved skin and hair condition.
Menstruation after stopping Jess
As a rule, stopping the use of Jess should be accompanied by a visit to the gynecologist. You should not stop taking the pills in the middle of the cycle, when the entire blister is not used. The peculiarity of the intake includes taking capsules for 28 days and you should stop taking the product after taking all the capsules and this is not discussed.
When a situation arises that requires urgent withdrawal of the drug, do not be afraid. Nothing bad will happen, you just need to understand that each body can react differently to the withdrawal of Jess and menstruation may be scanty.
Important: after stopping Jess, menstrual flow is often brown and very scanty. In rare cases, periods are heavy or they simply do not exist, and a long delay occurs. This is the body’s reaction to a sharp decrease in the level of sex hormones.
Spotting instead of normal periods can last up to 10–14 days. Situations where the discharge is too heavy and lasts longer than normal periods require consultation with a specialist.
Birth control pills provide all the hormones to the body and it has “forgot how” to produce them on its own. especially if taking OK was long-term. But within 2-3 cycles, menstruation should recover completely.
Menstruation after discontinuation of Jess is affected by:
- Woman's age . After 35 years, the body’s own reserves are depleted, so full restoration of menstruation can take up to 6 months.
- Duration of reception . If a woman takes Jess for many years, normalization of hormonal levels can last up to one year. Experts recommend taking a break of 3 months after one year of taking hormonal hormones.
Interesting: if a girl takes Jess for 1-2 months, after stopping it, two eggs can mature in the ovary at once. The body seems to stimulate its own ovulation, after which the chances of getting pregnant increase sharply.
The method of taking hormonal contraceptive pills is often used by doctors for infertility of unknown origin.
Jess Plus product
This is a special formula of the drug, including not only active, but also vitamin tablets that contain calcium lemomefolate. His indications are exactly the same as those of his predecessor. Only contraception for women with folate deficiency is added to the list. If you are planning a pregnancy soon, you can switch to Jess Nail. Reviews confirm that the lack of folic acid in the body quickly returns to normal. This is due to the fact that levomefolate is the active form of folate and is absorbed better than folic acid. And since during pregnancy the first thing that is formed is the neural tube, a deficiency of this element can lead to malformations of the nervous system.
It turns out that you are simultaneously protecting yourself and taking care of the baby’s health, in case you become pregnant immediately after stopping the drug or (this happens extremely rarely) while taking it. In general, B vitamins are very important for the female body, which is perhaps why the drug “Jess Nail” is becoming widespread. Reviews from women who took it indicate that the condition of their skin and hair improves.
Side effects
Studies have shown that some women taking the drug to protect against unwanted conception, get rid of acne and treat severe forms of cyclic syndrome may experience adverse reactions:
- nausea;
- pain in the mammary glands;
- periodic bleeding from the uterus;
- bleeding from the genital tract of unknown origin.
The most serious reaction may be the development of acute blockage in the arteries or veins.
After abortion and childbirth
If you had an abortion, or had a spontaneous abortion in the first trimester of pregnancy, or premature birth resulting in the death of the child, then you should start taking the drug the next day. But in this case, you should definitely consult your doctor. After giving birth, you need to wait until your first menstruation. If the baby is bottle-fed, then you will have to wait 3-4 months for this. Sometimes your doctor may allow you to start taking it earlier. If you are breastfeeding, then you need to discuss with your doctor the possibility of taking Jess (tablets). Side effects (reviews suggest that taking it makes recovery from abortion much easier) from the drug during this period are minimal, especially if you take it as prescribed by your doctor.
Release form and composition
The dosage form of Jessa is film-coated tablets: biconvex, round, the core at the break is almost white to white in color: the active ones are light pink, on one side there is an engraving in a regular hexagon in the form of the letters “DS”; placebos - white, on one side engraved in a regular hexagon in the form of the letters “DP” (28 pcs., including 24 active and 4 placebos, in blisters, in a folding book 1 or 3 blisters; 30 pcs. (active tablets) in blisters, 1 blister in flex cartridges, 1 or 3 flex cartridges in a cardboard box, possibly complete with a Clyk dispenser).
Active ingredients in 1 active tablet:
- ethinyl estradiol (in the form of betadex clathrate) – 0.02 mg;
- drospirenone – 3 mg.
Auxiliary components in 1 tablet (active/placebo):
- core: lactose monohydrate – 48.18/23.205 mg, microcrystalline cellulose – 0/54.21 mg, corn starch – 28/0 mg, magnesium stearate – 0.8/0.585 mg;
- shell: talc – 0.3036/0.2024 mg, hypromellose – 1.5168/1.0112 mg, titanium dioxide – 1.1748/0.7864 mg, red dye iron oxide – 0.0048/0 mg.
