Rimantadine: how to take, composition, contraindications

03.09.201661720

Viral infections strike people unexpectedly and can be difficult to cope with. Microorganisms consist of a chain of RNA and several proteins, which allows them to easily penetrate weak points and provoke diseases. And if there are no antibodies to the microbe in the immune system, then you won’t have to wait long for the disease: for example, the incubation period of the influenza virus ranges from 3 hours to 3 days. But not everything is as bad as it looks at first glance! The drug Remantadine has been used for the treatment and prevention of influenza for over 40 years, although there are certain restrictions.

A drug

• Effect of the drug
• Composition of the drug
• Indications for use
• Admission rules
• Taking medication for preventive purposes
• Contraindications
• Overdose and side effects

Composition and release form of the drug

It is immediately worth noting that the drug "Remantadine" for children is produced in two forms - syrup and tablets. The choice in this case depends on the age and condition of the child and, possibly, personal preferences.

The main active substance is rimantadine hydrochloride. Each tablet contains 50 mg of this component. As for excipients, lactose monohydrate, povidone, anhydrous colloidal silicon dioxide, as well as corn starch and magnesium stearate are also used in production.

The syrup is a thick, sweet liquid that is reddish or pink in color. The medicine is sold in 100 ml dark glass bottles. The active substance, of course, is the same rimantadine hydrochloride. One teaspoon (5 ml of syrup) contains 10 mg of this component. In addition, the syrup contains sugar, purified water, sodium alginate and dye.

What does rimantadine tablets help with and what is its composition and active ingredient?

Colds can have different names, but the root cause of their occurrence is infection of various organs, especially the upper respiratory tract by harmful microorganisms. They are divided into two groups: bacteria, viruses.

Medicine for viral infections

Rimantadine according to its pharmacological group is an antiviral agent. Its effect is especially active at the initial stage of infection of the patient. The drug is produced in the form of tablets in regular cardboard packaging.

The active ingredient is rimantadine hydrochloride. One tablet contains fifty milligrams of the active substance. There are also auxiliary elements: starch, lactose, calcium stearate, talc.

Composition of Rimantadine

What diseases is the drug used for?

Rimantadine is used for the treatment and prevention of influenza virus infections and encephalitis. It is effective for colds, acute respiratory infections, sore throat, rotavirus and herpes viruses. This remedy has the property of lowering the temperature and relieving the symptoms of diseases at the first stage of the disease.

Basic pharmacological properties

Today, many parents prefer to use Remantadine tablets, syrup for children. Reviews indicate that the drug is really effective. It is immediately worth noting that this is a synthetic product, the active components of which are adamantane derivatives. The drug blocks the transition of viral genetic material into the cell cytoplasm. At later stages of the disease, the drug interrupts the process of transcription of the viral genome and prevents new viral particles from leaving the cells. This drug is active against many strains of the influenza virus, especially influenza A.

After oral administration, the drug is quickly absorbed by the intestinal walls and enters the blood, where it binds to plasma proteins. In the liver, the active substances are deactivated, turning into metabolites, which are then excreted by the kidneys.

Taking the medicine provides a relatively quick effect - flu symptoms become less pronounced, the degree of serotological reactions decreases, and the process of recovery and restoration of the body is significantly accelerated.

Effect of the drug

The medicine was developed by American scientists in the 1960s, and at that time there was no more effective remedy. The manufacturer of Remantadine today is not only US companies: both domestic companies and neighboring countries have launched production. The popularity of the drug is determined by its ease of use and reliable suppression of the activity of several types of viruses. How does the medicine work on humans? To do this, you need to understand the mechanism of infection development.

When entering the body, the virus first penetrates healthy cells, after which it integrates its RNA into the process of transcription of nucleic acids - the cell is filled with pathogenic chains and becomes a focus of infection. At this stage, the drug Remantadine acts as a protective barrier, complicates the synthesis of the microbe and prevents the development of the disease as a whole. The medication blocks the transmission of the hereditary material of the virus into the cytoplasm due to the weakly basic nature of the active substance. In addition, the product inhibits the release of new microorganisms from the affected cell and increases the functionality of lymphocytes, which rush to attack unexpected guests with fresh strength.

Indications for use

In what cases do pediatricians prescribe the drug "Remantadine"? For children, this medicine is a fairly effective antiviral agent, so it is used to treat diseases of viral origin, including ARVI, influenza, etc. According to research, this drug alleviates the symptoms of the disease and speeds up the child’s recovery process.

There is another purpose for using the drug Remantadine. Syrup for children is also effective as a prophylactic agent. For example, a child can take the drug even before the onset of a flu or cold epidemic - in such cases, the risk of developing the disease is much lower, even if the child is constantly in a group. Remantadine is also used to prevent tick-borne encephalitis - the drug also copes well with this task.

Conditions for dispensing from pharmacies

The indication for taking Remantadin is the flu - an insidious infection that not only deprives us of our ability to work, but often also leads to much more dire consequences (including paralysis of the facial muscles and even death)

The number of new types of this virus reaches hundreds, and new “versions” are constantly appearing, so it is very important to carefully study the indications for taking the pills, they must affect a specific infection

For some time, the population was actively encouraged to get vaccinated against influenza, but then much more effective analogues of vaccinations, such as Remantadin, appeared. When exactly the medicine was created and why it was not in demand earlier, despite the affordable cost of the tablets, is difficult to say. The drug is contraindicated for children, but is indispensable for adult patients in the treatment of:

• early stages of influenza;
• to prevent the development of influenza viruses;
• for the prevention of viral tick-borne diseases;
• to prevent influenza during an epidemic or in contact with infected people.

Today the medicine is widely available and can be used by anyone (with the exception of children under 7 years of age, since there are no instructions for the use of Remantadine for young children).

Our website presents the current price of the drug, as well as the price of other antiviral drugs.

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* Instructions for medical use of the drug Remantadine are published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, YOU MUST CONSULT WITH A SPECIALIST

Syrup "Remantadine" for children: instructions

It’s worth noting right away that if you have symptoms, you should consult a doctor - a more serious illness is often hidden under the guise of a cold, so an examination by a specialist is still necessary. The treating pediatrician, of course, will select the form of the drug that is suitable for the child, as well as the most effective dosage.

This medicine is not used to treat children in the first year of life, which is due to the imperfect functioning of the baby’s kidneys - there is a possibility of accumulation of dangerous metabolites in the body. What does the dosage regimen look like for children 1-3 years old? On the first day you need to take 20 ml of syrup three times. On the second and third days, the daily dose is 40 ml, divided into two doses. On days 4-5 you need to drink 20 ml of syrup at a time.

The dosage of the drug "Remantadine" for children 3 years and older looks a little different. On the first day, the syrup should be taken three times, 30 ml each. On days 2-3 the daily amount is reduced to 60 ml (divided into two doses), and on days 4-5 a single dose of 30 ml is needed.

Pharmacokinetics

The medicine begins to act literally a couple of hours after the first use, and the maximum concentration of the substance in the blood is reached after 3-4 hours (the speed of action depends on metabolism). Moreover, the largest amount is observed in the mucous membranes of the respiratory tract: it is through these cells that viruses penetrate into the body.

The medicine is contraindicated in pregnant women

The medicinal substance is quickly and fairly completely absorbed in the digestive system. Metabolized in the liver, completely eliminated from the body after 1-2 days through the kidney filter. With minor liver dysfunction, the medicine does not cause significant harm.

Contraindications:

• pregnancy;
• age up to 7 years (applies only to tablets);
• severe pathology of the liver and kidneys;
• epilepsy;
• thyrotoxicosis;
• cerebral sclerosis;
• individual sensitivity to adamantane.

Side effects

From the digestive system: stomach pain, dry mouth; nausea, loss of appetite. An increased level of bilirubin in the blood was noticed after administration. People with epilepsy may have more frequent seizures.

In case of individual intolerance, the appearance of allergic rashes on the body is possible. Since the drug impairs concentration and some inhibition of the nervous system may occur, it should not be taken by drivers and persons whose professions require quick reactions.

If you notice one or more side effects, contact your physician. He will note the drug and recommend another antiviral agent.

It should be noted that the toxicological activity of Remantadine is low and side effects usually develop when the dosage is exceeded or the medication is taken for a long time.

Special instructions:

Remantadine enhances the stimulating effect of caffeine and weakens the activity of aspirin and paracetamol.

How to take Remantadine tablets for children?

As a rule, children from 7 to 14 years old take Remantadine tablets. The dosage for children is determined by the doctor; below are only general recommendations.

Children 7-11 years of age should take one tablet twice daily. Older children (11-14 years old) need to take one tablet three times a day. The course of treatment usually lasts about five days.

If we are talking about prevention, then children are prescribed to take one tablet a day for two weeks.

Remantadine

The product is intended for oral administration.

The dosage depends on the patient's age:

Orvirem and Algirem

The drugs are sold in the form of syrup, with a concentration of the active component of 2 mg/ml. They are packaged in 100 ml bottles. Liquid rimantadine is intended for use in children under 14 years of age. The maximum concentration of the main substance is 5 mg per 1 kg of weight.

The dosage of the drug depends on the age of the child:

Remantadine also has a number of analogues that are similar in action. They must be taken strictly according to the instructions after consultation with a pediatrician.

Arbidol

The main component of the drug is umifenovir. Arbidol is available in capsule and tablet form. The product is approved for use in children over 3 years of age.

It is prescribed for:

• acute respiratory viral infections;
• influenza type A and B;
• bronchitis;
• epidemics of viral diseases;
• secondary immunodeficiency;
• pneumonia;
• herpetic disease;
• decreased immunity;
• intestinal infections.

The dosage of Arbidol depends on age:

Tamiflu

The drug contains oseltamivir phosphate. Tamiflu is sold in several forms: capsules and powder. The product is intended for use in children from 6 months. The drug is prescribed for the treatment and prevention of influenza, as well as during epidemics of viral diseases. The dosage of Tamiflu depends on body weight.

Treatment:

• From 15 kg: 30 mg 2 times a day;
• 16-23 kg: 45 mg 2 times a day;
• 24-40 kg: 60 mg 2 times a day;
• from 41 kg: 75 mg 2 times a day.

Children over 6 months of age are recommended to be given a dose calculated from 3 mg of the active ingredient per 1 kg of body weight. Children over 13 years old should take 75 mg 2 times a day. Duration of use: 5 days.

Prevention:

• From 15 kg: 30 mg once;
• 16-23 kg: 45 mg once;
• 24-40 kg: 60 mg once;
• from 41 kg: 75 mg once.

Duration of treatment: 10 days.

When using powder to prepare a suspension, you must:

1. Measure out 52 ml of water.
2. Add it to the bottle.
3. Shake the container.

After dissolving the powder, the concentration of the active substance will be 12 mg/ml. For dosing, you need to draw up the suspension with the supplied syringe, which has special milligram marks.

Kagocel

The drug contains a patented sodium salt of the polymer Kagocel as the main compound. It is available in tablet form and is intended for use in children over 3 years of age.

Kagocel is prescribed for:

• flu;
• acute respiratory viral diseases;
• colds.

The dosage of Kagocel depends on age:

Relenza

The drug contains zanamivir. Relenza is produced in the form of an inhalation powder and is used in pediatrics from the age of 5 for the treatment and prevention of influenza types A and B. A special inhaler is included with the drug.

Regardless of age, when treating influenza, it is necessary to carry out 2 inhalations per day of 10 mg of the drug, that is, 2 doses at a time. The duration of treatment is 5 days. For prevention, it is necessary to carry out 2 inhalations per day of 5 mg of zanamivir for 10 days.

Procedure:

1. Lift the cap of the inhaler and pierce the packaging of the medicine.
2. Close the lid.
3. Exhale and insert the end of the mouthpiece into your mouth, closing it with your lips.
4. Take a slow, deep breath through the mouthpiece and remove it from your mouth.
5. Hold your breath and exhale slowly.
6. Pull the tray out all the way without touching the clamps, and push it back. This manipulation will allow the disk with part of one dose to rotate.
7. Repeat steps 3-5 3 times.

One disc contains 4 cells, which constitute 1 dose and contain only 5 mg of active substance. It is worth noting that exhaling into the inhaler is strictly prohibited.

The antiviral drug Remantadine is most effective in treating an incipient disease within the first 2 days. The instructions also indicate that the drug can alleviate the symptoms of the disease when used at a later date. Before using Remantadine, it is recommended to consult a pediatrician.

Are there any contraindications?

Today, many doctors prescribe the drug "Remantadine" for children. But are there any contraindications to taking it? In fact, not all categories of patients can use this remedy. In particular, the medicine is contraindicated in children with acute or chronic kidney and liver diseases. Contraindications also include some thyroid disorders, including thyrotoxicosis. And, of course, the drug should not be taken by children with hypersensitivity to any of its components.

Side effects and contraindications

Among the main contraindications are:

• Children under 7 years of age (medicine in tablet form).
• Epilepsy.
• Increased thyroid function.
• Cerebral atherosclerosis.
• Various forms of acute and chronic kidney and liver diseases.

Regardless of the form of release, the medicine should not be given to children with individual intolerance

!

In case of hyperthyroidism, the medicine can cause excessive irritability, tremors of the limbs, and sleep disturbances in the patient. In epilepsy and other forms of convulsive readiness, Remantadine contributes to the aggravation of these phenomena.

Some patients react to the drug with abdominal pain, nausea, vomiting, reluctance to eat, and various negative manifestations from the gastrointestinal tract.

Undesirable side reactions may also include:

• Phenomena of dizziness.
• Pain in the head.
• Lethargy and weakness.
• Noise in ears.
• The patient feels sleepy.
• Depressive state.
• Weakening of attention.
• Swelling in the throat and, as a result, a hoarse voice.
• Allergic reactions in the form of itching and other manifestations.

Rimantadine is an inexpensive antiviral drug. It is effective in the early stages of infection, but in later stages it does not bring tangible results. See photo below. Dosage form – tablets, capsules, syrup (for children).

What side effects can the drug cause?

Are there any risks if specialists prescribe the drug "Remantadine" for children? Reviews from parents and doctors indicate that the medicine is most often well tolerated by the body, without causing any complications. However, the occurrence of adverse reactions is still possible.

Sometimes patients experience allergic reactions, which are accompanied by redness, skin rashes, itching, hives, and slight swelling. Disturbances from the digestive system are also possible. Some children complain of dry mouth, flatulence, and pain in the stomach. Sometimes nausea, vomiting and diarrhea occur.

What else is Remantadine dangerous for children? In a number of cases, effects of the drug on the nervous system were noted. For example, side effects include headaches and dizziness, increased excitability, constant nervousness, sleep problems, anxiety, impaired concentration, etc.

If any disturbances occur, you should stop taking the medication for a while and consult a doctor.

Instructions for use of Rimantadine tablets

For an adult, a medicinal product based on adamantane derivatives may be useful in a number of cases. However, when taking it you should be careful, because there is a certain list of contraindications and possible side effects. And now about this in more detail.

Rimantadine tablets: what do they help with?

Among the indications for the use of an antiviral drug are the following:

• treatment of influenza type A;
• preventive measures against influenza A virus;
• reducing the degree of intoxication of the body due to viral diseases;
• prevention of tick-borne encephalitis.

Hemorrhoids kill the patient in 79% of cases

Regarding the treatment of influenza conditions, it is worth noting that the drug is especially effective in the early stages.

Speaking about this drug, it is worth raising the question of what Remantadine helps with. The two drugs are very similar in spelling of the name and have a common active ingredient - rimantadine hydrochloride. The drugs are interchangeable and their purposes are the same. The main difference between the “twins” is that the effect of Remantadine has been studied to a greater extent; this drug has fewer contraindications and side effects. For example, Remantadine is safer for children and can be used by women during pregnancy and lactation.

Reception features

Rimantadine tablets or capsules should be taken after meals. They are swallowed without crushing and washed down with plenty of water. For the effective effect of the drug on the body of an adult or adolescent over 14 years of age, the following dosages are recommended:

• on the first day of illness you need to take 2 tablets 3 times a day;
• on the second and third days, drink 2 tablets 2 times a day;
• on the fourth and fifth days you need to take 2 tablets once a day;
• To prevent diseases, take 1 tablet once a day for 1-2 weeks.

The duration of treatment is 5 days. The drug should be taken at the first sign of flu.

Main contraindications

The drug has a fairly wide range of contraindications, which are very important to study before starting use. Tablets should not be used:

• children under 7 years of age;
• for acute and chronic kidney diseases;
• for acute liver pathologies;
• if you are intolerant to lactose or other components of the drug;
• during pregnancy or breastfeeding.

In addition, it is important to consider conditions for which the drug is taken with increased caution. Before taking Rimantadine, you should consult your doctor if:

• epilepsy;
• liver failure;
• diseases of the gastrointestinal tract;
• chronic renal failure;
• arterial hypertension;
• atherosclerosis.

Side effects

When starting to take Rimantadine, you should take note of possible side effects. With a small probability, the following effects of the antiviral drug can be observed:

• sleep disorders;
• headache;
• state of anxiety;
• dizziness;
• feeling tired and overwhelmed;
• excessive excitability;
• loss of appetite;
• attacks of nausea;
• pain in the intestines;
• dry mouth;
• itching and redness on the skin;
• hives.

Carefully following the instructions for using Rimantadine tablets will help adults quickly get rid of viral diseases and prevent possible complications.

Are there any good analogues?

Today, many people are interested in questions about whether it is possible to replace the drug Remantadine with something. Only the attending physician has the right to select analogues for children, since everything here depends on the age of the child, his state of health, etc. Nevertheless, there are some medicines that have the same properties.

What to do if you couldn’t get Remantadine syrup for children at the pharmacy? "Orvirem" is another drug that will provide your baby with the same result. Moreover, this medication has the same active substance - rimantadine hydrochloride.

There are other, no less effective medications. For example, Remavir is a fairly good antiviral drug, which helps to cope with the flu at an early stage. And for younger children (from 1 to 7 years old), the drug “Algirem” is suitable, which also has antiviral properties.

pharmachologic effect

The herbal preparation Rimantadine has a pronounced antiviral effect. The use of tablets at an early stage of infection suppresses strains of virus A and also reduces their synthesis. The pharmacological effect is achieved by suppressing the reproduction of viral cells at the initial stage of infection.

For information! The components of the drug Remantadine have an effect on the tick-borne encephalitis virus.

The components of the medicine are metabolized in the liver, a third of the taken medicine is excreted during urination after 72 hours. In patients suffering from chronic renal failure, the active substance can accumulate in toxic concentrations, provided that the dosage is not adjusted in proportion to the decrease in creatinine clearance. It is worth noting that Remantadine instructions for use of tablets are divided into treatment and prevention of diseases.

The drug "Remantadine" for children: reviews from doctors and patients

Of course, when choosing the right medicine for a child, you need to pay attention to many facts. So what do doctors and patients say about the drug Remantadine for children? Reviews confirm that this remedy really does its job perfectly - the disease is much easier, and the recovery process is faster. Moreover, correct intake of Remantadine helps protect against colds even during an epidemic.

According to statistics, side effects occur rarely and, as a rule, are associated either with the presence of contraindications or with improper use of the drug. The drug "Remantadine" has another undoubted advantage - it is a relatively low price. But do not forget that before starting to take any drug you need to consult a doctor.

Negative reactions from people

The drug "Remantadine" has not only positive reviews, unfortunately, but also negative ones. Of course, there are few of them, but they still exist. Now let's try to figure out why some patients speak unflatteringly about this remedy.

Patients write that this drug did not help them cope with the flu. However, as the people themselves note, they began therapy with this remedy 3-4 days after the illness. Although the instructions for the drug clearly state that Remantadine tablets effectively fight the influenza virus at its initial stage. Therefore, the desired result was not observed.

Another thing is the dosage regimen. Patients who did not carefully read the instructions or did not open them at all, and did not take the drug as prescribed, experienced side effects: the appearance of a skin rash, itching, dizziness, and nausea. And such people blamed the medicine “Remantadine” for everything, although in fact the root of the evil was the patients themselves. Therefore, in order to prevent side effects from taking these pills, you must follow your doctor’s instructions and also carefully read the instructions for the medicine. And then there will be no negative reviews at all.

Interaction with other drugs

• Simultaneous use with drugs that alleviate epileptic seizures leads to a decrease in the effectiveness of the latter;
• Simultaneous use with Paracetamol or Acetylsalicylic acid leads to a decrease in the maximum concentration of Remantadine;
• Simultaneous use with drugs whose therapeutic effect is associated with enveloping the mucous membrane of the digestive system or the ability to bind and remove unwanted chemical compounds leads to a significant decrease in the absorption of Remantadine;
• Simultaneous use with drugs whose therapeutic effect is associated with a change in the acid-base balance of urine in the acidic direction, a decrease in the effectiveness of Remantadine is observed;
• Simultaneous use with drugs whose therapeutic effect is associated with a change in the acid-base balance of urine to the alkaline side leads to an increase in the effectiveness of Remantadine;
• Simultaneous use with Cimetidine leads to a decrease in the excretion of Remantadine from the body.

What does the drug help with?

The following types of action of Remantadine have been recorded:

1. Prevents viruses from entering cells. This allows the medicine to be used prophylactically - in case of epidemics and the risk of contracting viral infections.
2. It prevents the release of viruses from infected cells, that is, it stops the disease and does not allow agents to spread to healthy tissue.

As a result, the effect of Remantadine is therapeutic and prophylactic. When used, the likelihood of getting sick decreases; if infected, recovery occurs faster due to the suppression of viral reproduction.

Indications for use:

• influenza - group A strains (sphere of greatest effect - A2);
• herpes simplex 1 and 2 types;
• tick-borne encephalitis.

The medicine is often prescribed to weakened people during the autumn-winter increase in the incidence of colds, to protect against infection. The remedy helps well with constant and close communication with sick family members.

Who knows about the drug REMANTADINE and should it be taken if you have a fever or sore throat?

Answers:

Secret

If you have a sore throat, then no. Lugol - on the tonsils. orally - biseptol, ibuprofen, in extreme cases - erythromycin (tetracycline group). Keep your feet warm. Protect your liver. just in case, data: Remantadine is taken for early treatment (in adults and school-age children) and prevention (in adults) of influenza during an epidemic. Directions for use and dosage. Remantadine is taken orally (with water) after meals. THIS IS IMPORTANT, because you can ruin the mucous membrane! For influenza, adults take 2 tablets 3 times a day on the first day, 2 tablets 2 times on the second and third days, 2 tablets 1 time on the fourth day. On the first day of the disease, it is possible to use the drug once in a dose of 6 tablets. Children aged 7 to 10 years old are given rimantadine 1 tablet twice a day, from 11 to 14 years old - three times a day. Adults take rimantadine 1 tablet 1 time per day every day for 10-15 days. Side effect. When using rimantadine, discomfort in the stomach area is possible. Contraindications. The use of rimantadine is contraindicated in acute liver diseases, acute and phononic kidney diseases, thyrotoxicosis, and pregnancy.

Natalia

This is a drug for prevention, not treatment.

BITCH

A prophylactic drug... And from personal experience, it’s a dead poultice!

Svetlana

It definitely won’t help your throat, unless it’s Macropen))). Remantadine is taken for the flu)))

Abr Babr

Remantadine is an antiviral drug, and is taken mainly for the flu.

Baba Yaga

Remantadine is a drug taken for the flu. Do not confuse the disease with ARVI. Do you have aching bones? If not, then it is better to take Fervex and antiangin.

A preventive and therapeutic drug, effective against the group A strain of influenza. In all other cases it is ineffective.

Stewardess Zhanna

Remantadine is like throwing away money. Arbidol is the best!!!

Efficacy of the drug

Currently, the drug has only one indication - treatment and prevention of influenza A in children and adults. The earlier treatment is started, the higher the effect. It is advisable to start taking the medication in the first 24–48 hours after the first signs of illness appear.

The current situation is that during the process of virus mutation, many strains are not sensitive to the action of rimantadine. This applies to strains such as H3N2 (Hong Kong flu), H1N1 (swine flu) and many others. Therefore, using the drug may be useless.

In addition to influenza A, there are influenza B and C viruses. Based on the clinical picture, it is impossible to accurately determine the causative agent of the disease. This requires laboratory detection of the virus. But there are indications that the drug has an antitoxic effect against influenza B. The effectiveness of the drug in this case can be explained by stimulation of the immune system.

Currently, rimantadine is not recommended for the treatment or prevention of influenza. This drug is not included in the standard of care.

Rimantadine tablets: compatibility with alcohol

There is no information in the instructions about the interaction of these tablets with strong drinks. And yet, despite this, it would not hurt the patient to give up alcohol while taking the drug. Because, just like alcohol, without anything else, it weakens the human body’s immune system. Therefore, the beneficial effect of the tablets will disappear . All efforts to combat the infection will be useless.

Alcohol and Rimantadine

If you drink alcohol in addition to rimantadine, the effect on the liver will be worse . Tablets, albeit a little, disrupt the normal functioning of the liver, and alcohol even more so. This double exposure can result in big problems for the patient.

And if you have already taken a certain dose of alcohol, then it is better not to drink the drug. The minimum interval between the intoxicating drink and the tablets should be a six-hour break .

Moreover, if these incompatible components are consumed, then a person may have central nervous system disorders : loss of orientation, nervousness, other disorders - even severe depression.

Therefore, you should not experiment with your body. Do not drink alcohol while being treated with rimantadine.

Analogs

You can buy other medicines at the pharmacy that treat viral infections and are used to prevent influenza.

Structural analogues of the active substance (drugs of similar antiviral properties have also been added):

• Algirem;
• Amiksin (similar effect);
• Arbidol;
• Ingavirin;
• Kagocel;
• Orvirem;
• Rimantadine;
• Rimantadine Actitab;
• Rimantadine-STI;
• Rimantadine hydrochloride.

Is it better to take Remantadine or its analogues? This depends on the patient’s tolerance to the constituent components and the doctor’s recommendations. When choosing a drug, there is no need to focus on its price; the main thing is the therapeutic effect.

Drug interactions

Adsorbents and enveloping drugs reduce the absorption of the active substance.

Agents that acidify urine reduce the effectiveness of rimantadine, while agents that alkalize urine increase the effectiveness. The clearance of rimantadine is reduced when taking cimetidine.

Rimantadine reduces the effect of antiepileptic drugs.

The maximum concentration of the active substance in the blood is reduced by the simultaneous use of paracetamol and acetylsalicylic acid.

There are a number of medications that reduce the effectiveness of Remantadine. These include paracetamol (an analgesic and antipyretic that reduces fever and fever) and acetylsalicylic acid (also helps suppress inflammatory processes, reduce fever and pain).

Effect of medications

"Rimantadine" and "Remantadine" - what is the difference? The active ingredient of both medications is rimantadine hydrochloride. The second type of drug can have a dosage of 50 or 100 milligrams. Whereas the first medicine is available in a dose of 50 mg. Based on the fact that the medications have one active ingredient, we can say the following. They are analogues, or interchangeable drugs. Therefore, their operating mechanism is the same.

The drug becomes active when the virus enters a cell of the human body. The drug interacts with pathogenic microorganisms and does not allow them to multiply. The binding of viruses to cells is also blocked. The drug effectively eliminates many viral infections. It also has an immunomodulatory effect, allowing the body to regain its strength.

Reviews

There are many positive reviews about the medication from patients who not only treated the flu, but also used this drug for preventive purposes. They note that the incidence of this pathology has significantly decreased and they have become less likely to get the flu. Those who took the medication during the period of illness say that it relieves flu symptoms well or significantly weakens them. The disease in such patients progressed faster and easier than in those who did not use this medication.

We reviewed the instructions for use for Remantadine Actitab.

Rimantadine: how to take, composition, contraindications

Viral infections strike people unexpectedly and can be difficult to cope with.
Microorganisms consist of a chain of RNA and several proteins, which allows them to easily penetrate weak points and provoke diseases. And if there are no antibodies to the microbe in the immune system, then you won’t have to wait long for the disease: for example, the incubation period of the influenza virus ranges from 3 hours to 3 days. But not everything is as bad as it looks at first glance! The drug Remantadine has been used for the treatment and prevention of influenza for over 40 years, although there are certain restrictions. A drug

Effect of the drug

The medicine was developed by American scientists in the 1960s, and at that time there was no more effective remedy. The manufacturer of Remantadine today is not only US companies: both domestic companies and neighboring countries have launched production. The popularity of the drug is determined by its ease of use and reliable suppression of the activity of several types of viruses. How does the medicine work on humans? To do this, you need to understand the mechanism of infection development.

When entering the body, the virus first penetrates healthy cells, after which it integrates its RNA into the process of transcription of nucleic acids - the cell is filled with pathogenic chains and becomes a focus of infection. At this stage, the drug Remantadine acts as a protective barrier, complicates the synthesis of the microbe and prevents the development of the disease as a whole. The medication blocks the transmission of the hereditary material of the virus into the cytoplasm due to the weakly basic nature of the active substance. In addition, the product inhibits the release of new microorganisms from the affected cell and increases the functionality of lymphocytes, which rush to attack unexpected guests with fresh strength.

Composition of the drug

The synthetic compound rimantadine hydrochloride is used as the main substance responsible for the effect of the drug. The auxiliary components are starch, lactose, stearic acid, povidone and silicon dioxide - all this needs to be taken into account by people planning to take Remantadine tablets. However, there are other forms of release that will appeal to young patients.

Syrup for children Remantadine contains a reduced concentration of the active substance and is a reddish liquid with a thick consistency.

The basis of the drug is water in which sugar, sodium alginate and natural dye are dissolved. Manufacturers from different countries vary the composition of Remantadine, but this only applies to auxiliary components: for example, they include flavoring additives or change the amount of sugar.

Indications for use

Although the antiviral drug Remantadine was originally developed as a remedy for influenza, doctors later discovered its effectiveness in treating the human body with other microbes. Today the medicine is used for the following diseases:

• influenza type A;
• herpes type I and II;
• tick-borne encephalitis.

Immediately after the introduction of the invention into mass production, several flu epidemics were overcome, but the virus of this disease has an amazing ability to mutate. The antibiotic Remantadine, in turn, has a constant structure and does not adapt to each form of the microbe, which creates difficulties in treatment. Doctors note the antitoxic effect of the drug in the treatment of influenza B and even new types of infection, although one drug is not enough for complete healing.

Remantadine is most often used to treat influenza, but only at the early stage of the disease, when suppression of viral transcription is still possible. If the disease progresses in full force, then you should not hesitate with more serious medications: the flu can undermine your health for 1-2 weeks, and it is very difficult to overcome it.

Despite the specificity of the medication, doctors also advise using Remantadine for prevention during problematic times of the year - autumn and spring. Cough tablets in combination with this remedy and raspberry tea will prevent the development of ARVI in most cases, so it is worth taking care of your health in advance so as not to treat the consequences of your own negligence later.

Admission rules

You should take Remantadine for the flu only after eating food, and treatment should begin when the first symptoms appear. Of course, the signs of respiratory diseases are similar to each other, and anyone can mistake a common cold for the flu. However, inappropriate use of the drug should not worry the patient in such a situation: the medication activates the immune defense, which will fight the infection.

Remantadine tablets are taken depending on the person’s age, and the specific dosage is determined exclusively by the attending physician in accordance with the clinical picture. The official instructions recommend that on the first day of the onset of symptoms of a respiratory infection, a loading dose (100 mg three times a day) neutralizes the disease, on the second and third days, use the drug only twice a day, and on the fourth and fifth - once each. But this is how adults are advised to take Remantadine, but in the case of children and adolescents, a high concentration of the drug is unacceptable.

The drug is allowed to be given to a seven-year-old child in a daily dosage of 100 mg, and to adolescents 11-14 years old - 150 mg. The dosage regimen does not differ from the adult form of release, and on the first day the maximum possible amount of medication is consumed.

The course of treatment always lasts 5 days, and if the pills have no effect on the patient and the disease progresses, then you should not hesitate to consult a doctor.

Taking medication for preventive purposes

Antiviral drugs for children to prevent influenza are present in large quantities on the pharmaceutical market, so selecting a drug is an easy task. However, doctors recommend the use of children's Remantadine because it interferes with the transcription of the virus, which is an important factor in the early stages of the disease. In such cases, the medication is taken for 10 days, but you should not abuse the medication: 50 mg is the daily prophylactic dosage of Remantadine for both adults and children.

Prevention of influenza for children is on the minds of many parents, because the baby’s body does not have strong immunity and requires outside support. Doctors advise monitoring the child’s diet and preparing a variety of dishes that will compensate for the lack of chemical elements. If you cannot normalize the intake of nutrients naturally, purchasing a complex of vitamins and minerals would be an excellent option. The functioning of the immune system largely depends on the presence of the necessary components, so this issue should be addressed first.

Prevention for tick bites

People tend to be romantic and walk in the forest, but the danger of visiting open areas is underestimated by most. In nature, there are microbes that use insects as their home and means of transportation, without causing harm to them. In particular, the encephalitis virus lives in the body of certain species of ticks, common in Europe and Siberia.

Once in the blood of a person with an insect bite, the virus begins pathogenic activity and provokes the development of encephalitis, which, if left untreated, causes serious consequences. Remantadine will help prevent this course of events, although sometimes preventive measures will be in vain.

This insect pierces the skin painlessly thanks to special anabolic steroids in its saliva, and a person sometimes takes a week before noticing the unexpected invasion. If you take the tablets for a tick bite for three days, you will be able to avoid the disease in most cases. Doctors recommend drinking 50 mg for fifteen days, but the insect is often harmless and does not act as a carrier of infection. To confirm the danger of the disease, a laboratory analysis of the tick is required, so you should not rush to conclusions and rely on luck, ignoring prevention.

Contraindications

Individual intolerance or hypersensitivity to the components of the drug is the basis for discontinuation and treatment with Remantadine. The presence of skin rash and itching are the main signs of an allergic reaction, which, if they appear, will occur immediately after the first tablet. In addition, treatment and prevention of influenza for children and adults with this drug should be carried out taking into account the condition of the patient’s body. Taking the medication is prohibited if you have the following disorders:

1. Kidney and liver failure.
2. Thyroid diseases (thyrotoxicosis).
3. Age up to 7 years.
4. Pregnancy.
5. Lactation.

Contraindications for Remantadine must be observed, otherwise serious consequences are possible. It is worth dwelling in more detail on its use during pregnancy and lactation, because this question interests every expectant and breastfeeding mother.

Remantadine during pregnancy and lactation

Laboratory tests show high toxicity of the drug when administered in large doses, but studies have not been conducted specifically on pregnant women. During this period, doctors recommend replacing the medicine with analogues, which are present in abundance on the pharmaceutical market. In addition, rimantadine during breastfeeding is easily transferred into the baby's body and interferes with the normal development of the child due to the specific action of the constituent components, therefore the medication should not be used during lactation.

Overdose and side effects

The drug is used as prescribed by the doctor, observing the established norm, but sometimes the patient misses the time of taking the medicine and strives to make up for lost time in the following days by doubling the number of tablets. This should not be done under any circumstances: even Remantadine for children will cause intoxication, not to mention the adult dosage.

Tablets for the prevention of colds, flu and encephalitis will prevent these diseases when used correctly. However, doctors and pharmacists warn that the side effects of Remantadine are constant companions of treatment, and with an overdose they even intensify:

• intestinal dysfunction (pain, flatulence, nausea, vomiting, etc.);
• insomnia, fatigue;
• headache and dizziness;
• increased excitability;
• nervousness and anxiety;
• allergy.

The benefits of the medication can hardly be overestimated, because every person dreams of being healthy and not picking up an accidental infection. Remantadine prevents the multiplication of viruses during the incubation period, but if the side effects become pronounced, the drug will have to be discontinued.

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Consequences of taking higher doses of the drug

In case of overdose, the following deviations in condition were recorded:

• heart rhythm disturbances;
• overexcitement;
• tremor;
• heartburn, nausea;
• hallucinations.

Gastric lavage and elimination of symptoms are indicated. Hemodialysis removes only part of rimantadine.

Can I take it during pregnancy and lactation?

The use of Remantadine in any regimen is not recommended.

Use for liver or kidney dysfunction

Not prescribed for acute and chronic diseases of these organs.

When a remedy is needed

The effective action of the tablets helps when the body is affected by influenza and other colds.

These tablets contain compounds that can suppress the antiviral activity of pathogenic agents. It is advisable to take the tablets as prescribed by the doctor, following the dosages recommended by him.

What Rimantadine helps with can be understood by analyzing its content. The molecules of CC-methyl-1-adamantylmethylamine hydrochloride, which is an adamantane derivative, predominate in the described chemotherapeutic agent.

Thanks to this compound, the replication processes of viruses are inhibited in the body.

This is important at the initial stages of the disease entering the body, if the person has not previously taken antiviral drugs

Rimantadine, the indications for which are prescribed in the instructions, when taken regularly, helps to:

• slowing down the formation of viral shells;
• inhibition of the development of arboviral particles.

The regimen for taking this medicine provides for its use in the event of not only damage to the body by the usual form of viral influenza, but also in the development of pathologies in the body caused by B viruses. The results of virological studies confirm the effect of the described agent on specific protein molecules belonging to viral virions.

Liver cells involve the pills that enter the body into metabolic processes. Already on the third day from the moment of taking the medication, a fifth of the medicine leaves the body in urine.

Remantadine tablets indications for use

have the following:

• flu;
• viral encephalitis;
• cold symptoms.

The use regimen provides for the use of the medicine for adults and children from the age of seven when they are diagnosed with influenza.

Important! Adults can take this drug for preventive purposes.

Doctors' recommendations

Remantadine should be used only as prescribed by a doctor and in the quantities prescribed by the specialist. This takes into account not only the patient’s health status, but also other medications he is taking. For example, the antiviral drug in question reduces the effectiveness of drugs against epilepsy, and absorbents reduce the degree of absorption of Remantadine itself.

Also, doctors do not recommend combining an antiviral drug and alcohol - a combination of this kind significantly increases the likelihood of developing side effects, namely nausea, vomiting and diarrhea. If you have taken alcoholic beverages, you can take the tablet no earlier than 6 hours later. The opposite situation requires an even longer pause - after taking the medicine, alcohol can be consumed no earlier than 12 hours later.

special instructions

During treatment, there is a possibility of exacerbation of concomitant chronic diseases. In elderly people with arterial hypertension, the risk of developing hemorrhagic stroke increases; in patients with a history of epilepsy or simultaneously receiving anticonvulsant therapy, the risk of developing an epileptic seizure increases. In the latter case, the daily dose should not exceed 100 mg.

Prophylactic use of the drug is effective in cases of high risk of disease during an influenza epidemic, contacts with sick people, or the spread of infection in closed groups.

Description of the drug

Remantadine tablets were patented by pharmacists in 1965 in the USA. Later, experts conducted special tests among volunteers, due to which they were able to prove the high effectiveness of the drug. Today the drug belongs to the category of synthetic substances. This is one of the few derivatives of adamantane (a chemical compound that occurs naturally in petroleum). The tablets are effective for routine prevention and treatment of type A influenza, as well as to prevent the development of the active stage of tick-borne encephalitis.

When are medications prescribed?

What are the indications for Remantadine? The instructions for use indicate that the medicine is prescribed for viral infections, including influenza, encephalitis and others. The medication can also be used to prevent the described pathologies.

When is Rimantadine (tablets) prescribed? The instructions state that the indications for use of the medicine are preventive measures and treatment of viral diseases. So, if we compare, both described drugs have the same reasons for use.