Miramistin: composition, indications, dosage, side effects

Miramistin in gynecology is used as a solution with a concentration of 0.01%, completely ready for use. It has an effective effect on various types of microorganisms. Sometimes you can find this drug as an ointment, but its use is not so popular and is used more often in dermatology. Miramistin in solution is offered in 100 ml, 200 ml and 500 ml packaging, and ointment - 15 g.

Usage

Miramistin is used in gynecology in the following cases:

  • inflammation in the vaginal cavity;
  • fungal pathologies such as thrush;
  • inflammation occurring in the mucous layer of the uterus;
  • injured birth canal with suppuration of damage, in the period after childbirth;
  • treatment of sexually transmitted diseases, treatment of postpartum infections.

The use of Miramistin is permitted for pregnant women and is not contraindicated during breastfeeding.

Effect of the drug

Miramistin has a unique feature of local action on the affected areas and, without penetrating into the deeper layers of tissue, it has a local antiseptic and disinfectant effect. Another feature of Miramistin solutions is the ability to reduce the resistance of resistant viruses to antibiotic exposure, penetrating into pathogenic microorganisms and thereby disrupting their intercellular walls. The drug can make any types of staphylococci, streptococci, Pseudomonas aeruginosa and Escherichia coli more vulnerable. Miramistin has been successfully used as a means for the complex treatment of HIV and herpes.

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Miramistin 500 ml

An economical bottle, suitable for manipulations that require a large amount of the drug, as well as for use in hospitals and dressings.
Miramistin® has a wide spectrum of antimicrobial action, including hospital strains resistant to antibiotics. Increases the sensitivity of bacteria, fungi and protozoa to the action of antibiotics. Stimulates local protective reactions at the site of inflammation. The drug is not absorbed and does not have a local irritant or allergenic effect. ‹ Modern antiseptics: rebirth Up Miramistin - instructions for use ›

Application in gynecology

There are different ways to use Miramistin, and the success of the entire treatment process will directly depend on the appropriateness of the method. The most popular are the following:

  1. Tampons . A method used for the inflammatory process in the uterus or vaginal mucosa. Tampons soaked in the solution are inserted into the affected area. This remedy is used for endometritis, colpitis, and vaginitis. The duration of the course depends on individual indicators, but it should not be less than a week.
  2. Use of electrophoresis. This method allows the drug to be directed to the affected area using electrical currents. In the treatment of inflammatory diseases of the pelvic organs, this method is used in combination with therapeutic drugs.
  3. Using a douching solution. Used as a prophylactic after unprotected sexual intercourse to avoid the spread of sexually transmitted infections. After the procedure, it is recommended not to wash the genitals or have sexual intercourse for some time (at least 2 hours). The greatest effect from using this product can be expected if you use it no later than 2 hours after sexual intercourse.
  4. Injection of a solution into the genitourinary canal for urethritis and for preventive measures against sexual diseases.
  5. Miramistin spray should be used as a means of preventing the spread of infections during postpartum recovery or after a cesarean section. The spray is used to treat the vaginal cavity, and during a cesarean section, the incision and uterine area are irrigated with the spray.
  6. Miramistin is very effective for thrush and in such cases it is convenient to use this drug as a suppository. Miramistin suppositories are inserted into the vagina at night, the course of treatment lasts from 5 to 10 days. This method is much more effective than douching, since the medicinal composition remains in the vagina for a longer time.
  7. Miramistin ointment is used extremely rarely in gynecology , only when treating the infected surface of perineal wounds. The duration of use of the ointment depends on the extent of the lesion.

MIRAMISTIN 0.01% 50ML RO-R BOTTLE + GYNECOLOGICAL ATTACHMENT

Dosage form

Colorless, transparent liquid, foaming when shaken.

Compound

active substance: Benzyldimethyl[3-(myristoylamino)propyl]ammonium chloride monohydrate (in terms of anhydrous substance) - 0.1 g excipient: purified water - up to 1 l

Pharmacodynamics

Miramistin has a wide spectrum of antimicrobial action, including hospital strains resistant to antibiotics. The drug has a pronounced bactericidal effect against gram-positive (Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae, etc.), gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsiella spp., etc.), aerobic and anaerobic bacteria, determined in the form of monocultures and microbial associations, including hospital strains with multiresistance to antibiotics. It has an antifungal effect on ascomycetes of the genus Aspergillus and the genus Penicillium, yeast (Rhodotorula rubra, Torulopsis gabrata, etc.), and yeast-like fungi (Candida albicans, Candida tropicalis, Candida, krusei, Pityrosporum orbiculare (Malassezia furfur), etc. ), dermatophytes (Trychophyton rubrum, Trychophyton mentagrophytes, Trychophyton verrucosum, Trychophyton schoenleini, Trychophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseiim, Microsporum canis, etc.), as well as other pathogenic fungi, in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapy drugs. It has an antiviral effect, is active against complex viruses (herpes viruses, human immunodeficiency virus, etc.). Miramistin acts on pathogens of sexually transmitted diseases (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae, etc.). Effectively prevents infection of wounds and burns. Activates regeneration processes. Stimulates protective reactions at the site of application, due to the activation of the absorption and digestive functions of phagocytes, it potentiates the activity of the monocyte-macrophage system. It has pronounced hyperosmolar activity, as a result of which it stops wound and perifocal inflammation, absorbs purulent exudate, promoting the formation of a dry scab. Does not damage granulations and viable skin cells, does not inhibit marginal epithelialization. Does not have a local irritant effect or allergenic properties.

Pharmacokinetics

When applied topically, Miramistin does not have the ability to be absorbed through the skin and mucous membranes.

Side effects

In some cases, a slight burning sensation may occur at the site of application, which goes away on its own after 15-20 seconds and does not require discontinuation of the drug. Allergic reactions.

Selling Features

Available without a prescription

Indications

Otorhinolaryngology: complex treatment of acute and chronic otitis, sinusitis, tonsillitis, laryngitis, pharyngitis. In children aged 3 to 14 years, it is used for the complex treatment of acute pharyngitis and/or exacerbation of chronic tonsillitis. Dentistry: treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic treatment of removable dentures. Surgery, traumatology: prevention of suppuration and treatment of purulent wounds. Treatment of purulent-inflammatory processes of the musculoskeletal system. Obstetrics and gynecology: prevention and treatment of suppuration of postpartum injuries, wounds of the perineum and vagina, postpartum infections, inflammatory diseases (vulvovaginitis, endometritis). Combustiology: treatment of superficial and deep burns of II and IIIA degrees, preparation of burn wounds for dermatoplasty. Dermatology, venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet. Individual prevention of sexually transmitted diseases (syphilis, gonorrhea, chlamydia, trichomoniasis, genital herpes, genital candidiasis, etc.). Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of specific (chlamydia, trichomoniasis, gonorrhea) and nonspecific nature.

Contraindications

Individual intolerance to the drug.

Drug interactions

When used simultaneously with antibiotics, an increase in their antibacterial and antifungal properties was noted.

Should Miramistin be used during pregnancy?

During pregnancy, a woman experiences significant hormonal changes. In this regard, various diseases caused by hormonal imbalance may appear. The best treatment for such disorders in pregnant women, which does not cause harm to either the expectant mother or her child, is Miramistin. The biological substances included in its composition are not capable of harming the developing fetus throughout pregnancy. However, women, especially pregnant women, should not self-prescribe Miramistin treatment, since it is not able to be absorbed into tissues and the active substance, accumulating on the treated area, can lead to an overdose of the drug. Despite the fact that this remedy is completely harmless, it is better to avoid such situations so as not to cause the development of an allergic reaction in the newborn. Use Miramistin in the treatment during pregnancy, preferably in the form of napkins soaked in the substance. It is undesirable to do douching during this period of time, since deep irrigation of the vagina can provoke penetration of the drug into the uterine cavity, and this should not be allowed during pregnancy.

"Miramistin" for thrush

Gynecologists often prescribe this drug for the treatment of fungal diseases. This is due to the fact that the composition not only destroys viruses and bacteria, but also affects fungi. This correction is quite inexpensive compared to other treatment regimens. The price of Miramistin will be discussed below.

The dosage is always determined individually depending on the patient’s age and the severity of the pathology. However, the standard volume of the drug is from 10 to 50 milliliters. The course of treatment may vary and last from 7 to 14 days. During this period, it is worth completely eliminating sexual intercourse and following a certain diet. Sweet foods and baked goods often provoke candidiasis.

Precautionary measures

Despite the fact that the active component of the drug has an exclusively local effect on the affected area and does not affect neighboring organs of the body, Miramistin is nonetheless a medicinal agent and must be used correctly. When using, you must adhere to the following:

  • do not exceed the dosage;
  • if an allergy to a drug occurs, you must stop using it and replace it with a similar one;
  • If you experience unpleasant sensations in the form of a burning sensation, do not stop processing, and soon such deviations will disappear.

The use of this medical product in medical practice for more than 40 years has not shown a single case of adverse deviations in the state of the body in pregnant women or during breastfeeding. This, together with the high effectiveness of Miramistin, has led to the high popularity of the remedy.

How does the remedy work for thrush?

The drug actively reacts with fungi and destroys their membrane. The composition prevents the proliferation of pathological microorganisms. The solution has an antiseptic and antimicrobial effect on the mucous membrane of the vagina and cervix.

Within a few days after treatment, heavy discharge, itching and burning disappear. All these symptoms indicate the presence of thrush. Doctors note that you should not immediately stop treatment. You must complete the assigned course. Only in this case will you be able to get rid of the pathology.

Patient reviews

If we summarize the numerous reviews from patients about the use of Miramistin, we can conclude that it is effective. The number of dissatisfied patients is no more than one percent of the total number of respondents, the majority of reviews are very positive. The overwhelming number of women have had a fairly positive result from its use.

Olga, 29 years old:

I had problems in gynecology, I couldn’t get rid of the hormonal imbalance that causes thrush. The condition threatened the development of erosion. I tried several treatment methods and settled on Miramistin. Second month without relapse. I repeat the course of treatment on the recommendation of the gynecologist.

Lena K., Moscow:

I advise everyone to use this solution, especially after sexual intercourse with a partner in whom you are not entirely sure. You never know what situations happen in life. Therefore, the best remedy for unprotected sexual intercourse is Miramistin. In this case, it is better to use douching.

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