Polygynax - instructions for use, indications, composition, side effects, analogues and price

  • June 15, 2019
  • obstetrics and gynecology
  • Tatyana Andreeva

To treat female diseases, a gynecologist usually prescribes medications that come in the form of vaginal suppositories. Dissolving directly in the vagina, the drugs release active components that fight bacteria and fungi. Combination candles are very popular. They act on several infections at once, quickly eliminating the signs of the disease. An excellent example of such a drug is the Polygynax suppositories. What this medicine is for and how to use it correctly will be discussed in the article.

Release form

"Polygynax" is a drug for intravaginal use. It is presented in the form of candles that have a smooth surface and a round shape. Their color is pale yellow or beige. It contains a mixture of main components, as well as soybean oil and stabilizers. The drug is available in blisters of 6 or 12 suppositories. Instructions are included in the package along with the candles. There is no applicator for easy administration.

There is another similar drug - Polygynax Virgo. This medication is presented in the form of an emulsion without a gelatin shell. This medicine is intended for teenage girls and girls who cannot yet use suppositories.

Side effects during treatment

The use of Polygynax in some cases may be accompanied by side effects, which include:

  • Discomfort in the genital area (burning and itching).
  • The appearance of irritation in the vaginal area.
  • Allergic reactions, manifested in the form of skin rashes.

If any side effects occur, you should immediately consult a doctor. After examining the patient, the gynecologist will decide what further actions need to be taken. It may be necessary to replace the medication with a safer analogue and adjust the treatment regimen.

Compound

According to the instructions for use, Polygynax suppositories contain three types of antibiotics:

  1. Neomycin. This substance belongs to the group of aminoglycosides. It is effective against gram-positive and gram-negative microbes. The substance fights Proteus, E. coli, staphylococcus, enterococcus, tuberculosis bacteria and other pathogenic microorganisms;
  2. Polymyxin B Sulfate. This antibiotic, which is part of the Polygynax suppositories, is active against gram-negative bacteria, it kills Klebsiella, E. coli, enterobacteria, salmonella, and is also effective against dormant and growing microbes;
  3. Nystatin. This antibiotic is especially effective against candidiasis, aspergillus, blastomycetes and coccidioidosis.

Active ingredients of the drug

Polygynax suppositories contain three active ingredients that can cope with several types of infection at the same time:

  • neomycin sulfate;
  • polymyxin B sulfate;
  • nystatin.

Each of the substances has its own spectrum of activity, but acting simultaneously they are able to prevent the proliferation of all groups of microorganisms that cause colpitis or vaginitis.

Neomycin sulfate

This is an antibiotic from the group of aminoglycosides and has a wide spectrum of action. In small concentrations it has a bacteriostatic effect. At the same time, it penetrates the microbial cell, binds to specific receptors and stops protein synthesis. Bacteria lose the ability to reproduce.

In high concentrations it has a bactericidal effect. Neomycin causes direct damage to the cell membrane of the microbe, which leads to its death. Activity is manifested against the following microorganisms:

  • streptococci;
  • staphylococci;
  • coli;
  • salmonella;
  • shigella;
  • corynebacter;
  • Proteus.

Neomycin in Polygynax has only a local effect. At the same time, its suction is minimal. But in general, the drug is able to penetrate the placenta. Neomycin is dangerous for the fetus because, like other aminoglycosides, it has oto- and nephrotoxic effects. Therefore, the use of drugs containing neomycin during pregnancy is unacceptable.

Polymyxin B sulfate

Polypeptide antibiotic with bactericidal action. It attaches to the bacterial membrane, increases its permeability, which leads to cell disintegration. Resistance to the drug develops very slowly. Effective against the following microorganisms:

  • coli;
  • salmonella;
  • shigella;
  • Klebsiella;
  • bordetella;
  • enterobacter;
  • pseudomonas;
  • Haemophilus influenzae.

It penetrates tissue barriers poorly, but it is prescribed to pregnant women only for health reasons.

Nystatin

An antifungal agent from the group of polyene antibiotics. The peculiarity of the mechanism of action is based on the ability to integrate into the membrane of the fungus. In this case, a channel is formed through which water and electrolyte ions freely penetrate into the cell. Gradually this leads to the decay of the fungal cell.

Fungi of the genus Candida are sensitive to nystatin. Has no effect on the following microorganisms:

  • bacteria, including gardnerella;
  • viruses;
  • protozoa (Trichomonas).

Nystatin is practically not absorbed and has only a local effect.

Pharmacological properties

Vaginal suppositories "Polygynax" are notable for the fact that they do not have a negative effect on beneficial bacteria. The substances included in the composition do not suppress the activity of lactobacilli in the vaginal environment; they kill only conditionally pathogenic and pathogenic microbes.

The drug has antifungal and antibacterial properties, but is not effective against viruses. After inserting the suppository into the vagina, the shell of the drug softens, and its active ingredients come out. They are evenly distributed throughout the mucous membrane thanks to the oil base, which helps to completely eliminate the infection.

When is it time to get treatment?

The vagina is an environment with a certain balance of many microorganisms. Any changes in the flora are accompanied by the appearance of a certain type of discharge. Normally, the amount of vaginal discharge is insignificant. A healthy woman practically does not notice them. Discharge may increase:

  • during the period of ovulation;
  • before menstruation;
  • in pregnant women;
  • during sexual arousal.

During reproductive age, in 70% of cases, the appearance of noticeable discharge - leucorrhoea - is associated with inflammation. At the same time, the composition of the vaginal microflora changes.

Most people have opportunistic microorganisms. But it is not their quantity that matters, but the ratio with beneficial microorganisms. In healthy women, single cells of opportunistic flora can be detected in smears. The table shows normal and abnormal results of a vaginal smear.

Table - State of vaginal biocenosis

Smear readingsNormPathology
Flora— Lactobacilli (Dederlein rods); — up to 10 microbial cells of other morphotypes; - no trichomonas, gonococci, candida and key cells — Reduced number of lactobacilli; — cocci, gardnerella, and candida predominate (depending on the pathology); — specific microorganisms appear: gonococci, trichomonas
White blood cell count— Up to 10 in a smear from the vagina and urethra; - up to 30 in a smear from the cervical canal — More than 10 cells; - with gardnerellosis, the indicator may be within normal limits
EpitheliumUp to 15 cells per field of viewMore than 15 cells
SlimeA small amount ofSignificant amount

Very often, vaginitis or cervicitis is caused not by one microorganism, but by a microbial association. This is reflected in the choice of treatment regimen. In this case, you need to take an integrated approach, using drugs with multidirectional effects.

Polygynax suppositories: use in gynecology

This drug is prescribed for vaginal candidiasis, vaginitis of various natures, as well as bacterial lesions. The resistance of pathogenic microorganisms to the active substance of Polygynax develops slowly, which makes it possible to prescribe them for the treatment of chronic and nonspecific infections.

Suppositories are also suitable for the treatment of mixed infections that were caused by both fungi and bacteria at the same time. In some cases, the drug is used for prophylactic purposes. Vaginal capsules are prescribed before any gynecological interventions.

Prevention is necessary before diathermocoagulation of the cervix, placement of an intrauterine device and any other surgical operation. Suppositories are recommended for use for sanitizing the vagina before childbirth or abortion. Also, according to the instructions for use, it is advisable to use Polygynax suppositories before intracervical or intrauterine diagnostic procedures. This cleansing of the vagina from microbes speeds up recovery after surgery and reduces the risk of complications.

In what cases is it necessary and when is it contraindicated?

Indications for the use of Polygynax suppositories include treatment and prevention. For therapeutic purposes it is prescribed for the following conditions:

  • nonspecific vaginitis – inflammation caused by opportunistic flora;
  • fungal vaginitis - when thrush is complemented by microbial flora;
  • mixed vaginitis - a variety of flora was found in the smear;
  • vulvovagiitis - inflammation spread to the vestibule and vaginal cavity;
  • cervicovaginitis is an inflammatory reaction in the cervical canal and vagina.

For chlamydia, the use of Polygynax suppositories can only be part of a complex treatment.

Treatment with Polygynax is not prescribed for cystitis. This is an inflammation of the bladder, so vaginal capsules will not bring a therapeutic effect. Indications for use do not include anaerobic flora, such as gardnerella. This microbe is not sensitive to the action of the drug. In the treatment of adnexitis it can be used as an adjuvant: inflammation of the appendages is often accompanied by a similar reaction in the vagina.

Prevention of infections

For the purpose of prevention, Polygynax is prescribed in cases where it is necessary to prevent the proliferation of opportunistic flora. Most often, these conditions are associated with various manipulations of the genitals.

Preparing for surgery. If a woman is preparing for planned genital surgery, then she can start using suppositories a week in advance. This is especially true for a smear with a second or third degree of purity, when there is minor inflammation, but after surgery it can become a source of infection.

Preparing for childbirth. A newborn comes from almost sterile conditions through the vagina, rich in various microorganisms, into the outside world. Weakened local immunity during pregnancy leads to the activation of opportunistic flora. Often pregnant women are forced to use suppositories for most of their pregnancy.

A week before the planned date of birth, both natural and induced, you can use Polygynax with caution. But thrush alone is not an indication for prescription; it must be combined with elevated leukocytes and bacterial flora in the smear.

Diagnostic manipulations

Some invasive diagnostic methods can lead to ascending infection from the vagina. Diagnostic curettage and hysteroscopy should be performed with a sanitized vagina.

Treatment of the cervix. If a decision is made to treat cervical erosion using diathermocoagulation, then it is necessary to create a clean environment to avoid infection of the resulting wound. Therefore, prevention is carried out before and after manipulation.

"Polygynax" can be used when planning pregnancy. To prevent infection of the fetus in the early stages, as well as complications of the infection, it is necessary to sanitize the genital tract before conception. If the smear shows signs of inflammation, then full treatment is necessary. Sexual partners must undergo it at the same time. In men, the infection manifests itself in the form of urethritis. Sex during treatment is contraindicated.

When is another medicine needed?

The use of Polygynax is not permitted in all cases. Contraindications include the following conditions:

  • individual intolerance;
  • first trimester of pregnancy;
  • breastfeeding period.

In the second and third trimesters, treatment with suppositories is allowed if the benefit to the mother outweighs the risk to the fetus. If it is necessary to use this medicine during lactation, stop breastfeeding.

How to use

As a rule, vaginal suppositories are inserted into the vagina in the evening, preferably before bedtime. For treatment, a single use of the drug is sufficient. Depending on the purpose of use, the duration of the course may vary. For the treatment of diseases, capsules are prescribed for 12 days, and for preoperative treatment - for 6 days.

The drug can be used during menstruation. The instructions for using Polygynax suppositories indicate that skipping a dose does not reduce the effectiveness of the medicine. In this case, therapy is resumed and continued until the prescribed number of capsules is completed.

The medicine is administered immediately before bedtime so that it does not leak out during movement. One suppository is removed from the package and inserted into the vagina, pushing it as deep as possible with your finger. The drug "Polygynax Virgo" is used a little differently. After cutting the capsule, its thin part is inserted into the vagina, pressing on its expanded zone, squeezing the contents inside. The used capsule is thrown away.

The treatment and prophylactic course when using this drug lasts 6 days. During treatment, a woman must follow the following rules:

  • you can’t douche;
  • tampons cannot be used;
  • during this period, you should wear only cotton underwear;
  • you should refuse sexual intercourse;
  • You can dry yourself after a shower only with your own towel;
  • You can only wash yourself with your own washcloth.

Undesirable effects

Side effects of Polygynax manifest themselves in the form of local reactions:

  • burning;
  • itching;
  • redness;
  • allergy;
  • allergic eczema.

In this case, you should stop using the drug and report the reaction to your doctor. But reviews from doctors show that such reactions rarely develop if the instructions are followed correctly.

The duration of use also needs to be adjusted. It is not recommended to use more than the period specified in the instructions. Aminoglycosides can enter the systemic circulation in small quantities, which will lead to their side effects.

Exceeding the recommended dosage and course of treatment is theoretically fraught with the development of resistance in microorganisms to the drug. But no cases of overdose have been identified.

During the treatment period, you should not drink alcohol and should not have sex. It can reduce the therapeutic effect, the course of therapy will be ineffective. Spermicidal contraceptives also lose their effect during treatment, and latex condoms can be damaged by the components of the drug.

Analogues of "Poliginax" are "Amintax" and "Poliginax Virgo". The first of them has a similar composition, but is produced in Russia, unlike the original drug, which is produced in France. "Polygynax Virgo" is a dosage form intended for use in virgins. The capsule has a pointed end, which is cut off. Through it, the contents of the capsule are gently squeezed into the vagina. Reviews of Polygynax suppositories indicate the effectiveness of treatment with this drug and help almost everyone. You can see photos and videos in more detail.

Contraindications

According to the instructions for use of Polygynax suppositories, an absolute contraindication is individual intolerance to the components that make up the medication. "Virgo" can be used only after a doctor's prescription; the patient must be over 7 years old.

Women who are sensitive to polyene and aminoglycoside antibiotics, as well as those who are allergic to peanuts and soy, should use the drug with caution.

Pregnancy is not a contraindication to the use of Polygynax, but doctors prescribe it only if the expected benefits for the mother outweigh the risks for the child. Despite the fact that the dose of the active substance entering the blood is small, it is better not to take risks. For the same reason, suppositories are not prescribed to nursing mothers.

Reviews: “Didn’t suit me”

It turned out that, having caught a cold in my appendages, I didn’t find time for myself to immediately see a doctor, and I probably would have lived with pain in my lower abdomen if at one moment I wasn’t so twisted that I couldn’t straighten up. I had to go. The diagnosis was not reassuring; my inflammation developed into a chronic form. An ultrasound showed that the ovary was stuck to the uterus with adhesions, which is why there was such pain when walking and exercising. There was an offer to go to the hospital, which I refused, then a day hospital and warming up, the same refusal, since I have small children and there is no one to leave them with.

They prescribed treatment at home. There were many injections of antibiotics, then all sorts of douching and pills. All this lasted a month and a half. After all this, at a doctor’s appointment, I was prescribed Polygynax vaginal suppositories to complete the treatment. The candles turned out to be universal. They treat inflammation and thrush immediately. The composition includes a group of antibiotics and nystatin. This made me very happy, since thrush cannot be avoided from such a dose of antibiotics. The drug is prescribed for fungal, mixed vaginitis, inflammation of the appendages, and before surgery. They can also be taken for prevention. If I had known about them earlier, I would not have started my inflammation. Now they are always at home.

Natalya37, https://otzovik.com/review_294634.html

I used this drug 2 times in total: the 1st course was prescribed during pregnancy; 2nd - for a routine medical examination. Antibacterial suppositories "Poliginax" were first prescribed to me by a gynecologist for the treatment of thrush during pregnancy (by the way, thrush can occur as a reaction of the body to taking OCs), but the course of treatment gave only a temporary (short-lived) positive effect, then the thrush returned. The second time I was prescribed these suppositories was after a routine examination by a gynecologist (after undergoing tests, the results of which the doctor did not particularly like). I had no complaints about my health, but the doctor decided to prescribe a course of Polygynax for prevention. I, like an obedient patient, bought these suppositories and took the course. And after a couple of days I began to develop wild thrush, which I comprehensively treated (tablets + suppositories) with Pimafucin. The drug "Polygynax" absolutely did not suit me. Still, antibiotics greatly disturb (and destroy) the microflora of the mucous membranes, so they can be treated only as prescribed by a doctor and under his supervision (who will be able to adjust the therapy if there is a negative effect).

Nancy K, https://otzovik.com/review_879203.html

I took the full course - 12 suppositories. It was prescribed because of inflammation (there are a lot of leukocytes), and vaginal dryness, no unpleasant sensations, everything is as always with suppositories. I put it in at night and have a hygienic shower in the morning. The candles, naturally, partially leak out, and they also melt due to body temperature. I wore pads throughout the course and at night too. At night, so that there is no leakage of the candles, and during the day, the drug also partially comes out. I agree that first of all you need to read the instructions. I lived without sex and alcohol for 12 days. Treatment is treatment. Today I visited the gynecologist, she was shocked - the mucous membrane is fine, there is no redness. She took a smear and said it should be normal. So I have no complaints about polygynax! I had experience of treatment with Ovestin suppositories, so they almost burned everything out there exactly 10 minutes after insertion inside and everything itched and itched. This is not the case with polygenax. After Polygynax I put Ovestin on - it went without any problems at all, I think Ovestin burned because of inflammation, which Polygynax defeated! Hello, girls, and don’t delay pregnancy, because it may be too late. Infertility is a terrible diagnosis for both the body and especially the soul!

Natalya, https://www.woman.ru/health/woman-health/thread/3985912/2/

Analogs

There are no products with the same composition on the pharmaceutical market. Similar combinations are used in such medicines as Neotrizol, Terzhinan, Meratin Combi, Mikozhinaks. It is worth considering that these drugs, in addition to antibiotics, contain hormonal components.

The medicines listed above are slightly more expensive than the French medicine. In addition, they are not produced only for adult girls. The indications for the use of these drugs are the same.

Reviews

Patients praise Polygynax on medical forums. Suppositories have proven themselves well in gynecological practice when used according to strict indications. Experts characterize this medicine as effective, fast-acting, and not harmful to the body.

Women who used Polygynax during pregnancy give different reviews. In later stages, the medicine helps with fungal and bacterial infections without harming the health of the unborn child. However, reviews from some women indicate that after using the product during pregnancy, the baby experienced developmental abnormalities. They attribute this to the effects of the drug.

"Iodosept"

Many patients want to find analogues that are cheaper than Polygynax suppositories. Iodosept vaginal capsules are suitable for them. Their cost ranges from 140 to 170 rubles. This drug contains only one active ingredient - povidone iodine. It is effective against fungi and bacteria.

"Iodosept" is used for the same purposes as "Polygynax". Indications for use include many female fungal diseases. But you shouldn’t buy analogues without consulting a doctor. In any case, you need to consult a specialist.

Composition of the drug

The drug contains three active ingredients:

  • Nystatin.
  • Neomycin and polymyxin sulfates.

Nystatin in Polygynax inhibits the activity of Candida microorganisms. The last two active components are antibiotics that effectively help eliminate both gram-negative and gram-positive bacteria. At the same time, antibiotics do not have a noticeable effect on anaerobic microorganisms and streptococci.

The drug has a multidirectional effect on the body :

  • Antibacterial effect.
  • Antifungal action.
  • Increasing the level of metabolic processes in the vaginal mucosa.

The advantages of the medication include:

  • Uniform distribution of active ingredients.
  • Minimal penetration of active substances into the bloodstream.
  • Significant active action against many pathogenic organisms.

Main drug

The drug "Poliginax" is vaginal capsules. They are intended for the treatment of many female diseases, such as thrush, vaginitis, inflammation and dysbiosis. The cost of the medicine is about 400 rubles for 6 capsules. Treatment may require one or two packages of the drug.

The drug "Polygynax" is a convenient remedy for topical use. It contains nystatin (100 thousand IU), polymyxin sulfate (35 thousand IU) and neomycin sulfate (35 thousand IU). In addition, the drug also contains additional components.

Price for Polygynax

Often these suppositories are used for symptoms of thrush. According to reviews from many gynecological patients, Polygynax is an effective drug that not only eliminates the symptoms of the disease, but also prevents further infection.

Candle packaging Price (rubles)
6 items 330-400
12 pieces 550-650

Polygynax suppositories are especially often used in the treatment of thrush. It is important to note that based on the reviews of most patients, we can conclude that Polygynax is a truly powerful remedy for candidiasis, which not only eliminates all alarming symptoms, but also prevents further infection.

Of course, there are reviews of side effects, but such cases are extremely rare and are caused by a number of predisposing factors. One way or another, there is a concept of a certain “individual effectiveness”, when Polygynax suppositories “suited” some patients, but others considered them absolutely useless.

One way or another, this antifungal agent really works, productively eliminating pathogenic microorganisms localized in a woman’s vagina.

The price of Polygynax candles in capsules, 12 pieces - in retail chains - from 400 rubles.

Instructions for Polygynax Virgo - emulsion for intravaginal administration from the manufacturer of the drug Laboratory Innotec International (France)

Thrush is a diagnosis that every woman has encountered at least once in her life. That is why today a huge number of medicines aimed at eliminating a characteristic infection predominate on the free market. One of these drugs is Polygynax suppositories. General description of Polygynax suppositories First of all, it is necessary to clarify that Polygynax is an antifungal drug that is used primarily in gynecology. […]

Alexander Starovoytov

,

16:24Polygynax candles: instructions, application, reviews -

Thrush is a diagnosis that every woman has encountered at least once in her life. That is why today a huge number of medicines aimed at eliminating a characteristic infection predominate on the free market. One of these drugs is Polygynax suppositories. General description of Polygynax suppositories First of all, it is necessary to clarify that Polygynax is an antifungal drug that is used primarily in gynecology. […]

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Contraindications to Polygynax

At the very beginning of pregnancy, the use of the drug is not recommended because its effect on the developing fetus has not been studied. When the placental barrier is formed (after 14 weeks), taking the drug becomes possible.

Nursing mothers should not use the medicine because antibiotics may pass into breast milk. They can have a bad effect on the developing intestinal microflora of the child.

Otherwise, the drug acts mildly and where other remedies for thrush cannot be used, it can be used.

Exacerbation of chronic thrush occurs at any time, but the body is especially vulnerable when immunity decreases, hormonal imbalance, or relapses of other diseases. The completed treatment gives only a temporary effect, until a provoking factor appears.

Many women notice that they get thrush before or immediately after their period. Therefore, the approach of a new menstrual cycle is considered a tragedy, and due to the worsening infection, pregnancy becomes impossible, since the disease takes over the days of ovulation. What is the reason for the exacerbation of candidiasis and is there a connection between fungal infection and menstruation?

To understand why there may be thrush before menstruation, it is worth considering the main causes of exacerbation of the disease:

  • weakened immunity, as a result of which the body is not able to suppress pathogenic microorganisms;
  • antibiotic therapy leads to changes in the intestinal microflora and, as a result, the vagina, which contributes to the development of dysbiosis and candidiasis;
  • diabetes mellitus, which increases blood sugar, which the fungus likes to feed on for rapid reproduction;
  • protection or treatment with hormonal contraceptives, which increase the level of progesterone in the body, which causes thrush;
  • hormonal disorders leading to changes in microflora. They are caused by pregnancy and menstruation.

If thrush worsens every time before the onset of menstruation, or immediately after it, then this indicates that the disease has become chronic. And it is important to find the reason causing disruptions in the body.

The beginning of the menstrual cycle is the first day of bleeding. If the first symptoms of candidiasis appear consistently a week or several days before this event, this indicates disturbances in the functioning of the immune or endocrine system.

There is no direct connection between menstruation and candidiasis, but there may be a strange pattern. The idea that hormones are to blame is wrong. Before the onset of menstruation, progesterone levels increase, but in a healthy woman it remains within normal limits and does not cause hormonal imbalance.

Decreased immunity is also not suitable as a cause. A week before the expected period, the body is not exposed to stress. During menstruation, the immune system may be suppressed, but only with heavy bleeding and poor health, preventing normal rest and nutrition.

But the onset of pregnancy can cause the development of thrush a week before the expected period. Hormonal levels change sharply, and the body's protective functions often decrease. Therefore, pregnancy as a cause of thrush cannot be canceled.

If thrush appears immediately after the end of menstruation, this is explained by a change in the pH of the vaginal mucosa. This happens for two main reasons:

  • high humidity;
  • excessive hygiene.

The situation is aggravated by the use of pads and tampons, which not every woman has the opportunity to change every 3 hours. As a result, a greenhouse effect is created, the blood stagnates and becomes a favorable environment for the development of pathogenic microorganisms.

And after using pads with a fragrance and a synthetic surface, the delicate skin of intimate places can be covered with rashes and blisters, which, when injured, become an open wound for infection.

Excessive hygiene also leads to the development of candidiasis after menstruation.

Grandmother's advice that these products should be used to cleanse the skin during menstruation does not have medical confirmation. But excessive dryness of the mucous membranes is guaranteed, which contributes to the development of thrush.

  1. Delayed menstruation in women with a regular cycle and not planning a pregnancy is alarming.
  2. Violation of a stable rhythm indicates a malfunction in the body. Many women believe that the delay may occur after thrush, or against its background. Candidiasis itself cannot cause menstrual irregularities.
  3. In the initial stage, the disease affects only the mucous membranes; the development of the disease begins later, which is why doctors do not connect the delay with a fungal infection.
  4. If pregnancy is impossible, a woman has thrush and delay, then the reason lies in disturbances in the functioning of the body.

These factors are a consequence of exacerbation of a chronic disease, hormonal imbalance, and inflammatory process. Why exactly the delay occurred is diagnosed by the doctor after the examination.

The product has gained popularity due to its accessibility and effectiveness. Doctors recommend this drug for use and often prescribe suppositories to their patients. We invite you to read the comments of doctors regarding the therapeutic effects of suppositories on the reproductive system and on microorganisms that provoke the occurrence of gynecological diseases.

Antipova, E. N., gynecologist

Sergeeva, A, I., gynecologist

As we can see from the reviews of gynecologists, the effectiveness of Polygynax suppositories has been proven in laboratory studies and is an important pharmaceutical agent in the fight against various gynecological ailments. Before using it, it is important to have a face-to-face consultation with a gynecologist and, during the examination, determine the cause of the disease. Doctors also confirm the manufacturer’s recommendations that the use of suppositories should not be interrupted with the onset of the menstrual cycle.

Candida fungus is present in the human body, but becomes abnormally active under the influence of external factors. Under normal conditions, the microflora suppresses the spread of candidiasis, but if a malfunction occurs in the body, the fungus multiplies uncontrollably, which is manifested by itching, burning, and irritation of the vaginal mucosa. It is permissible to use Polygynax suppositories in such a situation, with the exception of the early stage of pregnancy. After the placental barrier has formed, and this is after 14 weeks of pregnancy, it is possible to use a similar drug containing antibiotics.

It is recommended to stop taking the drug in the following cases:

  • Early pregnancy (before 14 weeks)
  • Feeding a baby with breast milk
  • In case of complex forms of inflammatory processes

In other cases, the use of suppositories is permissible and appropriate, but with a doctor’s prescription. It is also worth noting that there are no high-quality analogues to this product today. As an alternative, it is recommended to purchase Polygynax Virgo. However, you should resort to purchasing this pharmaceutical only if the usual product is not available in any of the pharmacies.

Polygynax suppositories are prescribed for infectious and inflammatory diseases, such as:

  • Fungal vaginitis;
  • Nonspecific vaginitis;
  • Mixed vaginitis;
  • Cervicovaginitis;
  • Vulvovaginitis.

However, before starting treatment, it is necessary to determine the type of pathogen. Since drugs can negatively affect not only bacteria, but also normal microflora. Therefore, it is not advisable to use the drug without preliminary tests.

There are cases when it is contraindicated to use candles. In the first months of pregnancy, doctors prohibit the use of this drug because there is no information about how it will affect the fetus. After the 14th week of pregnancy, Polygynax can be used. During this period, it does not have any harmful properties on the body.

Also, you should not use this medicine during lactation. The substances contained in the drug can enter the baby’s intestinal tract with mother’s milk. In other cases, candles can be used without fear for your body.

The active components of the drug are neomycin, nystatin and polymyxin B. After introducing the suppository into the vaginal cavity, they are quickly absorbed into the bloodstream, eliminating inflammatory reactions in the body and destroying pathogenic agents, thus normalizing the microflora and preventing the further development of infection.

In childhood

For little girls and teenagers, a special form of suppositories is produced - Polygynax Virgo, intended for those who have not yet begun sexual activity.
Suppositories have the form of capsules with a pointed end, which, when used, must be pierced and, pressing on the shell, inserted into the vagina. After squeezing out the entire contents of the candle, the capsule itself should be thrown away. Girls need to administer the drug before bed, after the last visit to the toilet. The course of treatment is 6 days without breaks or omissions.

special instructions

Before starting treatment with Polygynax suppositories for inflammation, you should consult your doctor and pay attention to the following important points:

  • For maximum effectiveness of treatment, it is advisable to conduct an analysis of the vaginal mucosa (smear) to find out whether the infectious agent is sensitive to the active components of the drug.
  • The onset of menstruation does not necessarily require interruption of the course of treatment.
  • Excessive duration of the treatment period increases the risk of reinfection and may cause the development of forms of pathogens that are resistant to the active substances of the drug.
  • When using Polygynax for inflammation, you should not use latex contraceptives (condoms, caps).

The drug does not reduce the ability to concentrate and does not require changes to your usual lifestyle.

Mechanism of action of candles

Vaginal suppositories (capsules) Polygynax contain a combination of antibiotics (Neomycin, Polymyxin B) and an antifungal agent (Nystatin). The combined drug has a bactericidal effect on many strains of pathogenic microorganisms (staphylococci, enterobacteria, hemophilus influenzae, etc.

For the convenience of topical use of Polygynax suppositories, they contain auxiliary substances that give shape and a soft, uniform consistency (gelatin, dimethicone). The surfactant dimethicone, when introduced into the vagina, creates an enveloping film that promotes deep penetration of the drug into the tissue.

The high fungicidal activity of Polygynax against the spores and mycelium of yeast fungi makes it possible to achieve a positive treatment result in pregnant, weakened women who have chronic diseases of the reproductive organs with frequent relapses.

The use of Polygynax in pregnant women prevents intrauterine infection of the fetus, as well as infection during the movement of the child through the birth canal. Vaginal capsules (suppositories) Polygynax are contraindicated for use in the first trimester of pregnancy due to the risk of side effects of the active substances on the developing fetus.

It is not recommended to use Polygynax during breastfeeding. Despite the insignificant penetration of the drug into breast milk due to local use, you should stop feeding your baby breast milk during the treatment period.

The course of treatment with the drug lasts 6-12 days. During menstruation, the use of Polygynax is allowed, however, this therapy option is not very convenient for the patient. If menstruation occurs in the middle of the course, you can continue taking the drug after the end of menstrual flow.

Drug interactions

It is not recommended to combine the use of Polygynax suppositories with spermicidal contraceptives; this leads to a decrease in the effectiveness of the drug. It is also important to remember that the simultaneous use of vaginal suppositories and sexual intercourse with a condom increases the risk of its rupture.

It is not recommended to use suppositories simultaneously with medical means of local chemical contraception (spermicides, antiseptic creams and solutions). The substances included in their composition may reduce the effectiveness of the active substances of Polygynax.

Use only intravaginally. Capsules are administered deeply while lying on your back. It is advisable to perform the procedure in the evening. Using 1 candle per day is sufficient. The standard course of therapy takes 12 days. For prophylaxis, the drug is used for 6 days.

If the administration of a suppository is missed, treatment continues according to the established regimen without increasing the dosage.

The following analogues, applied topically and presented in the form of creams, suppositories, vaginal tablets or capsules, can replace the drug:

  1. "Sintomycin".
  2. "Meratin Combi".
  3. "Pimafucin".
  4. "Primafungin".
  5. "Dalacin."
  6. "Clindacin."
  7. "Cervugide".
  8. "Ecofucin".
  9. "Terzhinan."
  10. "Milagin."
  11. "Neotrizol".
  12. "Clindes."
  13. "Nystatin"
  14. "Natamycin."
  15. "Clindamycin."
  16. "Vagitsin."

The medication is not recommended for use in parallel with spermicides due to a possible decrease in the effectiveness of the active ingredients of the drug.

Why should Polygynax be used during menstruation?

Monthly bleeding in women causes hormonal changes, under the influence of which the mucous membrane of the internal cavity of the uterus is rejected. The bleeding surface is an excellent breeding ground for various infections, giving them an excellent opportunity to move up into the internal genital organs.

Thus, it is obvious that if a woman has signs of an infectious disease of the external genitalia, it is necessary to use antiseptics, including during menstruation, in order to prevent the transfer of bacteria to the ovaries, fallopian tubes and into the uterine cavity.

In addition, menstruation is a natural provocation that aggravates all inflammatory processes in the pelvis, which makes it possible to identify hidden infections that may not have manifested themselves before. It is always best to fight inflammation and microbes during an exacerbation, so Polygynax during menstruation is an excellent solution to infectious problems in the intimate area.

Nonspecific vaginitis

For nonspecific colpitis, suppositories are usually prescribed, the main components of which include a broad-spectrum antibacterial drug and/or an antiseptic. Good anti-inflammatory suppositories include:

  • Polygynax, consists of neomycin, nystatin, polymyxin B, is prescribed 2 times a day for a period of 5 - 14 days (price 6 pcs. 280 rub., 12 pcs. 450 rub.)
  • Terzhinan, a combination of ternidazole, neomycin, nystatin, prednisolone, is prescribed once a day in the evening for 10 days (price 240-400 rubles)
  • Meratin-combi, consists of ornidazole, neomycin, nystatin and prednisolone, 1 suppository is administered before bedtime for 10 days
  • Mikozhinax, a combination of metronidazole, chloramphenicol, dexamethasone and nystatin, duration of treatment 7 - 14 days, 1 - 2 suppositories per day are administered
  • Hexicon, the main substance is chlorhexidine digluconate, course of therapy is 7 - 10 days, 1 suppository must be administered daily (price 250 rubles)
  • Betadine - the active substance iodine, is prescribed twice a day for 6 - 12 days (280-350 rubles)

Use during menstruation

As you can see, some suppositories for thrush lose their effectiveness, but there is a way out. Just choose a product that is resistant to rinsing. If the drug has already been prescribed, but menstruation has begun, Betadine will be a safe temporary replacement. In any case, it will not harm, and you will not have to interrupt treatment.

Note! It is impossible to treat thrush with Hexicon, Bifidumbacterin, Femilex suppositories. And it's not even about menstruation. These medications are useless in the fight against candidiasis. Read the instructions and see for yourself.

The use of vaginal tablets or suppositories during menstrual periods is no different from normal use. If someone tells you to douche first, don't listen. You can't douche these days.

How to place a candle correctly:

  1. Wash your external genitalia.
  2. Wash your hands thoroughly with soap.
  3. Remove the candle from its packaging.
  4. Lie on your back, bend your legs.
  5. Carefully insert the suppository deeper.
  6. If you get dirty, run and wash your hands.
  7. Go back to bed and fall asleep.

In the morning, you may find that some strange substance is leaking along with your period. Don't worry - it's the remains of the candle coming out. By the way, your periods may become a different color, smell, or consistency - this is normal.

Is it possible to use Polygynax suppositories during menstruation?

The drug Polygynax is available in the form of suppositories and is used for the effective treatment of fungal, bacterial, and infectious infections in the female genital area. Due to the properties of actively combating harmful microorganisms, you can use Polygynax suppositories during menstruation. This is especially true for the need not to interrupt the course of treatment.

Composition of the drug

Among the main components of the medicine, it is important to highlight the antibiotics nystatin, polymyxin, neomycin. They neutralize inflammation and eliminate pain in the genital area. The safety of the drug is due to its gentle effect on the vaginal microflora, while maintaining an active fight against pathogenic microorganisms.

The drug belongs to the antibacterial category. It is effective at the stage of abnormal activity of pathogenic infections, bacteria and fungi, which occurs precisely at the beginning of the menstrual cycle.

The gentle effect on the vaginal mucosa when using vaginal suppositories is due to the presence of dimethylpolysiloxane in the composition. It is this component that nourishes and envelops the mucous layer of the vagina, followed by deep penetration of the substance inside.

Operating principle

Due to the localization of the product on the walls of the vagina, the medicine continues to fight inflammatory diseases and does not come out along with the bloody discharge of menstruation. In addition to relieving inflammation and irritation of the mucous membrane, the effectiveness of treatment is due to the elimination of itching and the cessation of uncharacteristic discharge with an unpleasant odor. The prescription of the medication and the duration of the treatment course are carried out by the gynecologist after examinations.

Thanks to the components of the drug and its properties, the effectiveness of treatment with vaginal suppositories is maintained during menstruation.

It is recommended to use Polygynax when diagnosing infectious lesions in the genital area. Candles are used in diagnostics:

  • vulvovaginitis (inflammatory processes in the vulva followed by irritation of the vaginal mucosa),
  • mixed vaginitis (inflammation of the vaginal mucosa, provoked by various reasons, for example, infectious processes),
  • cervicovaginitis (inflammation of the uterine lining),
  • fungal vaginitis (candidiasis, thrush).

The effect of using the medicine for any other infectious and inflammatory diseases can only be determined by the attending gynecologist.

Since Polygynax acts directly on pathogenic bacteria, in their absence it can affect the condition of the vaginal microflora.

It cannot always be used as a preventive measure. Before your appointment, you should consult and undergo an examination.

Contraindications

The use of vaginal suppositories is unacceptable in the first 14 weeks of pregnancy, and is also prohibited for women during breastfeeding. This is due to the possible penetration of the active substance into the baby’s gastrointestinal tract through breast milk, causing disturbances in its functioning.

The reproductive system becomes most vulnerable to the penetration of pathogens and the development of inflammatory processes during menstruation. This is due to changes in hormonal levels, as well as the property of some diseases to manifest themselves with bloody discharge (when menstruation ends, the pathology is asymptomatic).

The suppositories used are capable of destroying the cell walls of pathogenic microorganisms, neutralizing their activity. After agreeing on the correct treatment of existing diseases, it is recommended to insert Polygynax into the vagina according to the instructions or scheme proposed by the gynecologist.

Polozhinax should be taken at night by inserting into the vagina. The course of therapy itself cannot be interrupted, but its duration must be discussed in advance with the attending physician. As a rule, treatment lasts 12 days.

You can use the medicine only after consulting a doctor and checking the expiration date of the medicine itself. Polygynax belongs to the category of those few combination drugs that retain their effectiveness during menstruation and can be prescribed specifically at the beginning of the menstrual cycle.

The use of vaginal suppositories is relevant for the fight against most infectious and inflammatory diseases, for example, thrush. During treatment, patients should abstain from active sexual activity.

To determine the degree of sensitivity of existing pathologies to the effects of Polygynax, the patient may be recommended to undergo a bacterial culture (analysis). This allows you to eliminate possible side effects of the drug, prevent further complications and possible allergic reactions.

The use of the medication consists of using one capsule daily before bed for two weeks. One-time use of suppositories is possible during sanitation with surgery, gynecological manipulations, or before childbirth.

Mandatory consultation with a doctor is also due to the property of Polygynax suppositories to suppress the activity of topical spermicidal contraceptives taken. If there is a delay in menstruation after Polygynax, it is extremely important to consult a doctor in a timely manner and find out the true cause of the cycle disorder.

"Polygynax": analogues of the drug

A replacement to the described medicine is necessary when a woman experiences intolerance to certain components or an allergic reaction. In such situations, you should consult a doctor with your complaints. The specialist will be able to correctly adjust the treatment regimen.

The main substitutes for the drug include the following: Hexicon, Terzhinan, Clotrimazole, Vagilak. These medications contain a slightly different composition than the original drug. However, the effect of their use is absolutely the same. If we talk about substitutes for the described remedy that can be taken orally, these are Trichopolum, Nystatin, Metronidazole and others.

Clinical researches

During the treatment of vulvovaginitis, precise, step-by-step treatment plays an important role. The doctor selects safe and effective medications that prevent the proliferation of pathogenic microorganisms.

It is the candles from Innotera Shuzi that have a strong and pronounced antimycotic effect. Among other things, the high therapeutic effect of Polygynax is confirmed by laboratory tests by French doctors.

The clinical picture was as follows: itching, burning and discomfort in the intimate area. During the examination by gynecologists, swelling of the mucous membrane, cervix and external genitalia of the patients was detected. It was decided to treat with suppositories vaginally once a day for twelve days.

According to the results of the study, it was revealed that already 24 hours after the first dose of the drug, 90% of women noted the cessation of pain and discomfort in the vagina. The rest celebrated four days later.

What should you choose?

Consumers are often faced with the question of what to buy: Terzhinan or Polygynax? This interest arises due to the fact that both medications have identical composition. However, Terzhinan contains other additional components. These are prednisolone and trenidazole.

If we talk about the cost of drugs, then the drug "Terzhinan" has advantages. After all, it is produced in larger quantities at a more attractive price. However, this is not the only evaluation criterion. It is necessary to conduct a comparative analysis before choosing one remedy over another.

Composition and purpose

The drug is based on nystatin, neomycin, and polymyxin.
These antibiotics act on inflammatory processes in the eyes and eliminate pain in the shortest possible time. The main advantage of Polygynax is the safety of use during menstruation. The components of the medicine are localized on the walls of the vagina, which prevents their further exit along with menstruation. Suppositories do not disturb the microflora of the genital organ; they actively act exclusively on pathogenic organisms.

They are prescribed for infectious diseases such as:

  • Fungal vaginitis
  • Vulvovaginitis
  • Cervicovaginitis
  • Mixed vaginitis

Considering that menstruation is a natural provocation that can aggravate inflammatory processes caused by an infectious disease, which until some time did not make themselves felt, it is simply necessary to use pharmaceuticals such as Polygynax.

It is much more effective to fight pathogenic organisms during the period of their abnormal activity. Thus, we find that this drug is an effective means of preventing the entry of microorganisms into the fallopian tubes, ovaries and uterine cavity.

How does Polygynax work?

The pharmacological action of vaginal capsules is aimed at the antifungal and antibacterial effect, which is provided by the active ingredients of the drug.

Nystatin:

  • exhibits an inhibitory effect on candidal fungi;
  • it affects the cell membrane of microorganisms, destroying it:
  • this leads to the inability to reproduce, maintain normal life functions, and subsequently to the complete death of fungal cells.

It is known that it is Candida fungi that provoke thrush. Due to the presence of nystatin in the composition, Polygynax may be effective for thrush.

Neomycin and polymyxin. These components are active against many both gram-positive and gram-negative bacteria. They destroy the structure of these microorganisms, which leads to their rapid death. Polymyxin with neomycin is active against bacteria such as:

  • Pseudomonas aeruginosa;
  • enterococci;
  • Staphylococcus aureus;
  • ureaplasma;
  • hemophilus influenzae, etc.

The action of Polygynax is also aimed at improving the trophic processes that occur in the vaginal mucosa.

Colpitis caused by Trichomonas

When the vaginal mucosa becomes inflamed, we talk about colpitis (vaginitis). Depending on the infectious agent that caused the inflammatory process, vaginitis can be specific (for example, trichomonas, fungal, gonorrheal, etc.) and nonspecific (staphylococcal, streptococcal, polymicrobial). Distinctive signs of colpitis are unpleasant sensations in the area of ​​the external genitalia (itching, burning are unbearable), an increase in vaginal leucorrhoea, as a rule, they have an unpleasant odor, a possible increase in temperature, pain in the lower abdomen, and urination disorders.

The main importance in the treatment of colpitis is the prescription of local therapy aimed at destroying pathogenic microorganisms and suppressing their activity. In the first 3–4 days, douching is prescribed (no more than 2 times a day, see how to do douching correctly) with antiseptic solutions (chlorhexidine, rivanol, sodium bicarbonate, potassium permanganate) and/or decoctions of medicinal herbs (calendula, chamomile, lemon balm , sage). Anti-inflammatory suppositories are prescribed simultaneously with douching.

If Trichomonas are found in the vaginal contents, suppositories with Metronidazole (antimicrobial action, effective against anaerobic microorganisms - Trichomonas) and its derivatives are prescribed:

  • Ginalgin, Klion D, Trichopolum, Flagyl, Pitrid 1 per day for 10 days.

Other suppositories are also widely used:

  • Tinidazole (Gaynomax suppositories) for 10 days
  • Macmiror complex (500 rubles) consists of nifuratel and nystatin, therefore it is used for chlamydia, candidiasis, trichomoniasis and nonspecific vaginitis, used in a course of 8 days, one at a time before bedtime
  • Terzhinan
  • Meratin-combi
  • Mikozhinax one daily for 10 days
  • Trichomonacid course for 10 days
  • Trichocide twice a day
  • Neo-penotran (700-800 rubles) - contains metronidazole and miconazole, twice a day for two weeks
  • Hexicon for 7 – 20 days three times a day.

Treatment with anti-inflammatory suppositories for trichomonas colpitis is carried out over a three-month period (immediately after menstruation) in cycles of 10 days.

In the treatment of candidal colpitis, suppositories with an antifungal effect are used: nystatin, natamycin, clotrimazole, canesten. Antifungal creams may be prescribed: pimafucort, miconazole and oral tablets (flucostat, pimafucin, see antifungal drugs in tablets), and also see a detailed review of all suppositories for thrush.

After etiotropic therapy (suppression of activity and death of the pathogen), the second stage in the treatment of colpitis begins, aimed at reviving the normal microflora of the vagina. The purpose of the second stage is to create conditions for the proliferation of lactobacilli and increase their number. The list of candles used includes:

  • Bifidumbacterin (contains live bifidobacteria) is prescribed 1 suppository twice a day for 5 - 10 days.
  • Bifikol (dried bifidobacteria) daily, one course for 7 - 10 days.
  • Acylact 1 time per day in the evening for 10 days (about 110 rubles).
  • Vagilak (500 rubles), Laktozhinal (400-450 rubles), these are lactobacilli, 1 vaginal capsule in the morning and evening for a total cycle of 10 days.

In addition, the contents of ampoules with bifidobacteria and lactobacilli are diluted with water and administered intravaginally on tampons (colibacterin, bificol, bifidumbacterin).

Polygynax suppositories - instructions for use

Polygynax suppositories are used vaginally in the amount of two capsules per day. It is important to note that immediately after inserting the suppository, it is advisable to stay in a horizontal position for some time.

The course of treatment varies from six to 10 days. In the first case, we are talking more about prevention, and in the second, about therapeutic therapy. Sometimes such therapy can take a longer period.

If a characteristic disease is detected, a complete examination of both sexual partners is necessary, as well as complete abstinence from sexual intercourse during treatment. It is necessary to maintain personal hygiene, wear natural cotton underwear, and stop introducing hygienic tampons.

When combined with other medications, it is important to remember that Polygynax suppositories can significantly suppress the activity of local spermicidal contraceptives.

Indications for the use of Polygynax are diseases of the genitourinary system in women that are infectious in nature and accompanied by an inflammatory process. The most common ones include:

  • Fungal vaginitis.
  • Nonspecific vaginitis.
  • Bacterial vaginitis.
  • Cervicovaginitis.
  • Thrush.

Fungal vaginitis

A characteristic feature of this form of vaginitis is a strong unpleasant odor emanating from the vaginal discharge. The disease is provoked by fungi of the genus Candida, which change the microflora of the genital organ, providing conditions for normal life.

Candida fungi cause fungal vaginitis

It is provoked by a violation of the trophism of vaginal tissues. Polygynax successfully combats such symptoms of nonspecific vaginitis as:

  • changes in the structure of the vaginal mucosa;
  • discharge, which can be of varying severity, including purulent;
  • itching that begins as a result of the irritating effect of the discharge.

When several or at least one harmful microorganism appears in the vagina, they immediately begin to activate pathogenic processes, changing the microflora. The sooner the action of Polygynax begins, the faster it will be possible to get rid of bacteria.

The inflammatory process of the cervix can begin for various reasons. For successful treatment, it is necessary to start using antibacterial drugs, among which Polygynax is prescribed most often, as early as possible.

Thrush

Polygynax relieves inflammation of the vaginal mucosa and additionally eliminates symptoms such as:

  • curdled discharge;
  • feeling of itching;
  • pain when urinating;
  • smell with a characteristic sour tint.

Polygynax suppositories can also be prescribed for prophylactic purposes in order to prevent the occurrence of gynecological infectious diseases. This therapy is required in the following cases:

  • before performing gynecological operations;
  • before childbirth;
  • before and after the spiral insertion procedure;
  • before any diagnostic procedures inside the uterus.

Polygynax suppositories are administered vaginally, 1 piece per day. It is advisable to do this before bed, so as not to get out of bed later. If it is not possible to do this in the evening, then after the procedure you still need to take a horizontal position and lie down for at least 10–15 minutes.

Doctors can prescribe Polygynax suppositories to prevent thrush

The duration of treatment is 12 days. If the drug is prescribed for preventive purposes, then 6 suppositories administered vaginally for 6 days will be sufficient. If 1 or 2 procedures were missed during treatment, further use of the drug must be resumed without dosage adjustment.

Doctors recommend carrying out the procedure for inserting a suppository while lying on your back. In this position, the body relaxes as much as possible, including the pelvic muscles. The medicine must be administered carefully so as not to cause pain, using only a little pressure.

If menstruation begins while using the medication, there is no need to stop therapy. Doctors still recommend choosing the time of treatment so that it does not coincide with critical days. If this is not possible, tampons should not be administered simultaneously with capsules.

How to insert a suppository into the vagina

Contraindications to the use of Polygynax are:

  • individual intolerance to one of the active or additional components included in the drug;
  • first trimester of pregnancy;
  • breastfeeding period.

Bacteriological research, how it happens

During pregnancy in the second and third trimester, the use of Polygynax is permissible, but this must be done strictly as prescribed by a doctor and under his constant supervision.

Before you start using the medicine, you need to take a smear and conduct a bacteriological study. If it turns out that vaginitis or another disease is caused by microorganisms that are insensitive to the active ingredients of the drug, then its use is contraindicated.

The simultaneous use of Polygynax with any medications containing spermicides is contraindicated. Otherwise, the fungicidal effect (antifungal) of the drug will be absent.

Do you need to take a squirt in the morning after the Polygynax suppository? Regarding the first comment, I think that it is prescribed for bacterial vaginosis. I would like to ask about candles. The fact is that the doctor prescribed Polygynax for me for 10 nights. They come in 6 and 12 capsules.

Intravaginally. Lying on your back, 1 capsule. inserted deep into the vagina in the evening before bed. The course of treatment is 12 days. Preventive course - 6 days.

If you miss 1 or more capsules, you should resume taking the drug at the usual dose.

If the patient has infectious and inflammatory pathologies of the genital organs caused by pathogenic microorganisms, the doctor prescribes the use of suppositories containing an antifungal antibiotic. Polygynax suppositories are recommended in the following cases:

  • the presence of nonspecific fungal vaginitis;
  • with vaginal candidiasis;
  • if the patient was diagnosed with vulvovaginitis, vulvitis;
  • with cervicovaginitis;
  • for the prevention of genital organs caused by inflammation or infections;
  • during sanitation of the birth canal, abortion;
  • as preparation for surgical interventions in the genital area;
  • to prepare for diagnosing the space inside the uterus;
  • for prevention before childbirth;
  • before diathermocoagulation of the cervix and after the procedure.

Sometimes suppositories are prescribed for the treatment of cystitis, especially often in its chronic forms or complications. In addition, the drug can be used to prevent the development of inflammatory processes, which is important before a planned surgical intervention (in the localization of the genital organs), before and after cauterization of uterine cervical erosion, before diagnostic procedures performed intrauterinely and on the eve of childbirth.

Thrush should be treated regularly with Polygynax suppositories. Only through systematic use of the drug can pathogenic bacteria on the vaginal surface be completely destroyed. A single course of therapy, as a rule, is unable to completely rid a woman of bacterial infections.

Often, to treat thrush, a 12-day course of using suppositories is needed. The capsules are administered before bedtime, and it is better to do this while lying down, after carrying out hygiene procedures.

For preventive purposes, suppositories are used for 6 days. If a woman has missed taking the drug once or several times, she should resume therapy as soon as possible and continue as usual.

  • Before the procedure, you must wash your hands thoroughly without soap;
  • It is better to administer suppositories in a lying position (the recommended depth is equal to the length of a finger, otherwise the drug will flow out after dissolution);
  • it is recommended not to change the horizontal position for at least 15 minutes after inserting the suppository to ensure maximum safety of the product;
  • After the procedure, you need to wear a sanitary pad so that the released product does not stain your underwear.

Polygynax capsules should be inserted into the vagina one at a time. The procedure is recommended to be carried out before bedtime, for twelve days, during a course of treatment and six days for preventive purposes.

The most effective result of application will be if you follow a few simple recommendations:

  • before inserting the capsule, you must wash your hands with warm water, without using hygiene products - without soap;
  • capsule must be administered while lying down. It must be carefully pushed with a finger inside the vagina and the medicine must be deepened to the length of a finger - this is the optimal depth for the capsule. If the depth is insufficient, the medicine from the capsule can leak out or the capsule itself will come out without dissolving;
  • upon completion of the procedure, you need to lie down for 20-30 minutes, during this time the membrane will dissolve and the contents will be distributed over the surface of the vagina;
  • After administering the medicine, it is necessary to use a sanitary pad, because usually part of the medicine comes out.

It is necessary to focus attention on the fact that longer use of the product can negatively affect its effectiveness. The period of use is limited due to the development of resistance of pathogenic microflora to the active substances of the drug.

When treating with Polygynax, you should not use latex condoms. The course of treatment cannot be interrupted during menstruation; capsules can be administered despite the discharge. During treatment, it is advisable to refrain from drinking drinks containing alcohol.

The manufacturer has provided for the release of a special form of the drug called Polygynax Virgo - virgo translated from Latin means virgin, maiden, intended for the treatment of girls and adolescents.

The product is produced in special capsules with a pointed tip. Before insertion, you need to cut it off with scissors, then insert it into the vagina and squeeze out all the contents, and dispose of the empty capsule.

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