Special instructions for the use of trichopolum
Trichopolum should be prescribed with caution to patients with severe liver failure, because how, as a result of a slowdown in metabolism, the concentration of metronidazole and its metabolites in plasma increases
Caution is required when prescribing Trichopolum to patients with suppression of bone marrow hematopoiesis and central nervous system functions, as well as to elderly patients. The appearance of ataxia, dizziness and any other deterioration in the neurological status of patients requires discontinuation of treatment
During long-term therapy with metronidazole (more than 10 days), peripheral blood patterns and liver function should be monitored.
With leukopenia, the possibility of continuing treatment depends on the risk of developing an infectious process. The use of metronidazole should be avoided in patients with porphyria.
When treating trichomonas vaginitis in women and trichomonas urethritis in men, it is necessary to abstain from sexual activity. Simultaneous treatment of sexual partners is mandatory. After treatment for trichomoniasis, control tests should be carried out during three consecutive cycles before and after menstruation.
After treatment of giardiasis, if symptoms persist, 3 stool tests should be performed after 3-4 weeks at intervals of several days (in some successfully treated patients, lactose intolerance caused by infestation may persist for several weeks or months, resembling the symptoms of giardiasis).
Patients should refrain from drinking alcohol during therapy with metronidazole, as well as for at least 48 hours after completion of treatment, due to the possibility of developing disulfiram-like reactions: cramping abdominal pain, nausea, vomiting, headache, sudden flushing of blood. face.
During treatment with metronidazole, urine may become dark or red-brown in color due to the presence of water-soluble dyes. Trichopolum can cause immobilization of treponemes, which leads to a false-positive Nelson test.
It is not recommended to use Trichopolum in combination with amoxicillin in children and adolescents under 18 years of age.
When taking the drug, you should avoid potentially hazardous activities that require increased concentration and speed of psychomotor reactions, especially driving vehicles and servicing machinery.
Overdose of Trichopolum
Long-term use of the drug in high doses often leads to severe complications. Overdose is diagnosed by the increase in the above side effects. The development of uncontrollable vomiting, paresthesia and even convulsions is likely. A toxic disorder of the kidneys and liver is diagnosed.
If an overdose occurs, stop taking the drug immediately and then seek medical help. Before the doctors arrive, you should try to rinse your stomach by drinking a large amount of clean water and take enterosorbents. In a hospital setting, the patient is prescribed symptomatic treatment. There is no specific antidote; hemodialysis is not advisable.
Indications
What is Trichopolum prescribed for? The main cause is infectious and inflammatory diseases that are caused by microorganisms sensitive to the drug.
- Bacterial vaginosis.
- Trichomoniasis.
- Amoebiasis.
- Giardiasis.
- Ulcerative gingivitis, odontogenic infections.
"Trichopol" is prescribed for anaerobic bacterial infections, gynecological, abluminal, sepsis, bacteremia, infections of joints and bones, soft tissues, skin, respiratory tract infections. Trichopolum is also used to treat Helicobacter pylori for stomach and duodenal ulcers. The drug is used for prophylaxis before surgeries on the genitals and gastrointestinal tract. “Trichopol” is especially effective for bacterial vaginosis, giardiasis, trichomoniasis, and anaerobic infections.
In the case of pancreatitis, Trichopolum is used to eliminate the bacterium Helicobacter pylori, which infects the stomach area, damages the mucous membrane, and causes various inflammatory processes. As a result of such damage, gastrointestinal diseases such as gastritis and ulcers can occur. Trichopolum is often prescribed after operations performed on the gastrointestinal tract, as this prevents the formation of complications.
In what cases should women consult a gynecologist? Since Trichopolum is used to treat sexually transmitted infections, in case of burning, itching in the vagina, purulent discharge, nagging pain in the lower abdomen and other unpleasant symptoms, you should visit a specialist. Trichomoniasis and vaginitis can cause serious consequences, including infertility. During treatment with Trichopolum, sexual rest should be observed. Both partners usually undergo therapy. After treatment, sexual intercourse should be protected.
Is it possible to postpone treatment of trichomoniasis and vaginal dysbiosis until the birth of the child?
Most often, trichomoniasis in women is complicated by inflammation of the external genitalia and perineum, and rarely by cystitis. During pregnancy, the causative agent of trichomoniasis, Trichomonas vaginalis, can trigger the process of premature birth and provoke the birth of a low-weight baby.
At
bacterial vaginosis
a woman becomes vulnerable to inflammatory and infectious diseases of the female genital organs. This happens because in the microflora inhabiting the vagina, the number of lactobacilli sharply decreases (normally their content should be at least 95%). Lactobacilli produce lactic acid, which inhibits the growth of opportunistic and pathogenic microorganisms.
The drug is contraindicated for use in children under 3 years of age. It is not recommended to use Trichopolum in combination with amoxicillin in children and adolescents under 18 years of age.
Trichopolum - instructions for use
https://youtube.com/watch?v=2TYC-KYNAeI
Symptomatic trichomoniasis
Trichopolum is prescribed as a treatment for symptomatic trichomoniasis if the presence of Trichomonas in the body is confirmed by appropriate laboratory tests.
Asymptomatic trichomoniasis
Trichopolum can be prescribed to women with disorders such as endocervicitis, cervicitis or cervical erosion. Since there is evidence that the presence of Trichomonas in the body can negatively affect the accuracy of cytological smear tests, the tests are repeated after the parasite is destroyed.
Simultaneous treatment of partners: since Trichomonas vaginalis is transmitted sexually, even in the absence of symptoms in one or both partners, their simultaneous treatment is necessary.
If the partner of an infected person tests negative for trichomoniasis, he must make his own decisions about treatment.
Trichopolum - instructions. When making such a decision, it is necessary to take into account that in the absence of symptoms in a male partner, it can be very difficult to identify trichomonas, and even negative test results do not always guarantee the absence of infection.
At the same time, if a man has not undergone treatment, there is a high probability of reinfection in a woman. Therefore, treatment of both partners is usually recommended, even if only one of them shows signs of trichomoniasis.
Amoebiasis
Trichopolum is indicated in the treatment of acute intestinal amebiasis (amebic dysentery) and amoebic liver abscess. In patients with amoebic liver abscess, taking trichopolum does not eliminate the need to drain pus from the liver.
Anaerobic bacterial infections
Trichopolum is used to treat serious infections caused by anaerobic bacteria. It is prescribed to prevent such infections after operations. In case of mixed aerobic and anaerobic infection, in addition to Trichopolum, other antimicrobial agents are prescribed.
To reduce the risk of bacteria developing drug resistance, trichopolum should be prescribed only in cases where the presence of an infection is confirmed by tests, or there is good reason to suspect that the patient is infected, or that he will be particularly vulnerable to infectious agents (as after surgery).
More specifically, Trichopolum is used to treat the following infections:
- intra-abdominal infections, including peritonitis, intra-abdominal abscess, liver abscess, caused by bacteria from the genera Bacteroides, Clostridium, Eubacterium, Peptococcus niger, and Peptostreptococcus;
- skin infections caused by bacteria from the genera Bacteroides, Clostridium, Peptococcus niger, Peptostreptococcus, and Fusobacterium;
- gynecological infections, including endometritis, endometriosis, tubo-ovarian abscess;
- bacterial sepsis, caused by bacteria from the genus Bacteroides and Clostridium;
- infections of bone tissue and joints (Trichopolum is prescribed as part of additional therapy) caused by Bacteroides bacteria;
- central nervous system infections caused by Bacteroides bacteria;
- lower respiratory tract infections, including pneumonia, empyema and lung abscess, caused by bacteria of the genus Bacteroides;
- endocarditis caused by Bacteroides bacteria.
Efficacy in trichomoniasis
Indications for the use of the drug "Trichopol" include diseases such as trichomoniasis, gonorrhea and chlamydia.
It often helps women in the systemic treatment of asymptomatic and symptomatic trichomoniasis, and is used to prevent the development of the disease in a partner.
It is important to know! For preventive purposes, it is recommended to take the drug even if the partner’s test result is negative.
Indications for use
- Trichomoniasis, amoebiasis, giardiasis.
- Vaginitis caused by microorganisms sensitive to the drug.
- Infections caused by anaerobic bacteria (including peritonitis, abdominal and liver abscesses, endometritis, ovarian and fallopian tube abscesses, postoperative complications, pneumonia, pleural empyema, lung abscess, meningitis, brain abscess, skin infections, bone infections, sepsis. Endocarditis.
Used to prevent complications during surgical interventions on the colon, appendectomy, and gynecological operations. In the treatment of mixed bacterial infections (aerobic and anaerobic), usually in combination with an appropriately selected antibiotic and for the eradication of Helicobacter pylori in duodenal or gastric ulcers, in combination with a bismuth preparation and an antibiotic.
Trichopolum tablets and suppositories: what is suitable for the treatment of gynecological diseases
Most often, trichopolum is part of the complex therapy of peptic ulcers and gastritis, and is used for protozoal invasion and sexually transmitted diseases.
Trichopolum is a classic representative of the 5-nitroimidazole group (does not belong to the group of antibiotics). Has pronounced effects against protozoa and some bacteria. Application area:
- with trichomoniasis caused by disease and amoebiasis;
- for eradication of helicobacter pylori;
- with giardiasis;
- with ureaplasma;
- indicated for children against worms;
- with gardnerellosis;
- with inflammation of the urethra;
- with sore throat;
- in veterinary medicine (for dogs);
- with thrush;
- helps with cystitis;
- for gynecological diseases of women;
- for intestinal infections, liver abscesses and peritonitis.
Until recently, Trichopolum was used only in the treatment of Trichomonas infections. In modern medical practice, the range of its use has expanded significantly; the medicine is successfully used to treat many infectious diseases.
- For acute and chronic trichomoniasis.
- For the treatment and prevention of infections caused by anaerobic microorganisms during surgical interventions. The list includes peritonitis, abscesses (abdominal cavity and liver, fallopian tubes and ovaries, lung, brain), endometriosis, sepsis, dermatological and bone infections, pneumonia and purulent pleurisy, meningitis, endocarditis.
- In the treatment of mixed aerobic and anaerobic infections (usually in combination therapy with an antibiotic that affects aerobic bacteria).
- For chronic alcoholism. Why Trichopolum for alcoholics: metronidazole suppresses the activity of an enzyme that takes part in the metabolic processes of ethyl alcohol, therefore, during the simultaneous use of alcohol-containing drinks and this drug, patients become more sensitive to alcohol and develop intolerance to the latter.
- For peptic ulcer of the gastrointestinal tract (Trichopolum is here as a component of complex treatment).
- For the prevention of complications after surgical interventions on the intestines, after gynecological operations and removal of appendicitis.
Patients with malignant tumors should remember that Trichopolum increases their sensitivity to radiation, accelerates regenerative processes, and increases sensitivity to ethanol.
Signs of a digestive system disorder:
- poor appetite or its complete absence, metallic taste and dry mouth, change in taste;
- epigastric pain, diarrhea or constipation, intestinal colic, nausea and vomiting;
- manifestation of stomatitis and glossitis;
- rarely - pancreatitis, liver dysfunction, as shown by functional tests.
Trichopolum has several forms of release:
- Gynecological suppositories or tablets. This is a special form of a medicinal substance that treats various infectious diseases of MPS.
- Tablets for oral administration.
- A solution for douching or for intravenous administration.
In the treatment of female ailments, gynecologists prefer to use suppositories or vaginal tablets, which act locally without irritating the gastrointestinal tract. Candles have three main shapes:
- ovoid;
- flat;
- spherical.
Benefits of candles:
- Rapid absorption into the blood.
- Does not lose its properties during absorption.
- Suppositories do not leave a mark on the internal organs: liver and kidneys.
- Does not weaken the immune system.
- Hypoallergenic.
- They act locally.
- Simplicity and ease of use.
- They are securely attached to the mucous membrane and have a therapeutic effect on the site of the disease.
Indications for the use of Trichopolum in gynecology:
- trichomoniasis;
- endometritis;
- vaginitis;
- chlamydia;
- gonorrhea.
General information about Trichopolum
The tablets are small in size and have a white-yellowish tone. Shape: flat and round, with a dividing strip. When exposed to direct light, they acquire a rich yellow tint. One tablet of this medicine contains:
The medicine is produced in strips of 10 pieces. The box includes 2 plates, that is, 20 tablets. It is also produced in the form of suppositories, which are intended for vaginal use and solutions for intravenous injection. Each package of medicine contains instructions for use, which must be read carefully before starting therapy. Sold in pharmacies only upon presentation of a prescription.
The active ingredient of this medicine (Metronidazole), which is highly active in relation to:
- Gram-positive microorganism - Peptostreptococcus spp., Peptococcus spp., Clostridium spp., Eubacterium spp;
- Obligate anaerobes - Prevotella spp., Veillonella spp., Fusobacterium spp., (Prevotella disiens, Prevotella buccae, Prevotella bivia); Bacteroides spp. (including Bacteroides vulgates, Bacteroides thetaiotaomicron, Bacteroides ovatus, Bacteroides distasonis, Bacteroides fragilis.);
- Other microbes - Lamblia spp, Giardia intestinalis, Gardnerella vaginalis, Entamoeba histolytica, Trichomonas vaginalis.
The drug does not exhibit a bactericidal effect against some bacteria, viruses and fungi. With mixed flora (aerobes and anaerobes), metronidazole has synergistic effects with antibiotics that are effective against simple aerobes.
Metronidazole significantly increases the sensitivity of tumor formations to radiation, causing sensitization to ethanol, that is, it stimulates reparative processes.
When treated with this drug in parallel with amoxicillin, activity against Helicobacter pylori is observed, since amoxicillin suppresses the emergence of resistance to trichopolum (its active substance).
Trichopolum or Metronidazole – which is better?
Metronidazole is a Russian substitute for Trichopolum. Available in tablets for oral and intravaginal administration. Has antibacterial and antiprotozoal effects.
Trichopolum is the same as Metronidazole, only imported. It differs in the quality of raw materials, the frequency of unwanted side reactions, the country of origin and the price.
Buyers are interested in questions about whether it is possible to replace Metronidazole with Trichopolum and what is the difference between them. Both drugs contain the same active ingredient, which provides antimicrobial and antiprotozoal effects. It determines certain indications and contraindications, side effects, and interactions with other medications.
Both are available with a prescription and can be used interchangeably without specialist advice. They differ in quality and price: the imported drug Trichopolum has a milder effect, is less likely to cause unwanted reactions, and is more expensive.
Side effects
Side effects usually occur due to improper use of the drug, namely in overdoses, and manifest themselves differently in relation to the organs and systems of the body:
- Pancytopenia is when there is a decrease in the blood (red blood cells, leukocytes, platelets and platelets.);
- Neutropenia is an increased susceptibility to bacteria and fungi, as a result of which immunity decreases and the body becomes less resistant to infections;
- Thrombocytopenia - a decrease in thrombotitis in the blood;
- Agranulocytosis - a sharp decrease in granulocytes in the blood;
- Leukopenia is a decrease in white blood cells.
From bones and muscles:
Myalgia is muscle pain due to cell hypertonicity.
Allergic reactions:
- Hives;
- Nasal congestion;
- Arthralgia – pain in the joints;
- Fever;
- Itching;
- Skin rashes;
- Exudative erythema multiforme is a disease of the mucous membranes and skin.
From the reproductive and urinary systems:
- Pain inside the vagina;
- Urine is reddish-brown in color;
- Urinary incontinence;
- Polyuria;
- Cystitis is an inflammatory process occurring in the urinary system;
- Dysuria is a disturbance or difficulty in urinating.
From the side of the central nervous system:
- Cramps are involuntary muscle contractions;
- Hallucinations are disturbances of perception;
- Unclear thinking;
- Weakness, sleep disturbance;
- Depression is a serious mental disorder;
- Irritability, severe excitability;
- Peripheral neuropathy – nerve disorders;
- Dizziness or just pain in the head;
- Impaired motor coordination - lack of ability to perform precise movements;
- Encephalopathy - in rare cases.
From the gastrointestinal tract:
- Cholestatic hepatitis - damage to liver cells;
- Jaundice is yellowing of the skin, a symptom of liver disease;
- Pancreatitis is an inflammatory process in the pancreas;
- Impaired liver function;
- Dry mouth;
- Glossitis - inflammation of the tongue;
- Stomatitis is inflammation of the oral mucosa;
- Unpleasant metallic taste in the mouth;
- Diarrhea - stool instability;
- Decreased or complete lack of appetite;
- Impaired taste;
- Constipation - stool disorders;
- Intestinal colic - sharp paroxysmal pain in the intestines;
- Anorexia - severe weight loss;
- Epigastric pain - manifests itself in the upper or middle part of the abdomen;
- Nausea;
- Urge to vomit.
Reviews from doctors indicate that there have been no deaths from taking large doses of the drug in medicine. There is no antidote to the medicine, so in case of overdose, it is necessary to perform gastric lavage and maintenance therapy.
Feedback from patients showed that the side effects of the drug are insignificant compared to the therapeutic effect.
Reviews from doctors
In the daily practice of a doctor, Trichopolum is used very often. Excellent therapeutic effect and high efficiency are the main qualities of this medicine. Doctors and patients leave only positive reviews about the drug.
After studying the information on the request “Trichopolum during pregnancy reviews” from the author, a pharmacist with 13 years of practical experience in the industry, it began to gradually blow the roof off, excuse the lack of speech.
The overwhelming majority of information turned out to be not reviews, but messages on forums like: “I’m pregnant, the doctor prescribed Trichopolum, I’ve read all sorts of nasty things about it. Girls, what should we do???” I categorically refuse to repeat most of the comments under such cries of the soul due to the complete medical illiteracy of the people who wrote them.
Therefore, I will simply summarize what I read and present here my own impressions and thoughts from the heap of passions I read.
- If you come across a question from a future mother about whether to drink Trichopolum, I recommend forgetting all the letters of the Russian language as soon as you get to the comments. 99% of advice is scary and even more confusing. In your situation do you need it?
- I have repeatedly come across reports that Trichopolum is used to treat thrush. Not true. Thrush is a fungal infection, and Trichopolum does not affect fungi,
- Among the issues that concern expectant mothers, the problem of taking Trichopolum during a period when the woman did not know about her pregnancy is often mentioned. But before you grab your head and run to have an abortion, pay attention to the following fact. After fertilization, it takes approximately 5-6 days for the egg to move through the fallopian tubes and subsequently settle in the uterine cavity. A complete supply of oxygen and nutrients to the embryo through the placenta begins from the 3rd week of pregnancy, and from the same period the formation of key organs and systems begins. For about 20 days, the egg primarily “prepares” for transformation into the “human” appearance that we see in the pictures. The risk of developing serious complications in the fetus begins from the period when a woman can detect a delay in menstruation and stop taking the drug. In addition, do not discount the wisdom of Mother Nature, who also does not sleep and mercilessly gets rid of pregnancies that she considers untenable. In most cases, a woman will not even recognize that she was pregnant. Unfortunately, such protection does not always work, but the arsenal of modern medicine allows us to diagnose many serious pathologies during pregnancy. Therefore, it is too early to get upset.
- In some comments I came across information that the gynecologist did not like the appearance of the vaginal discharge, and she immediately prescribed Trichopolum. The prescription of this drug must be supported by the result of a study of secretions. Do not run ahead of the locomotive and be patient - the few days it takes to carry out the analysis will not radically change the situation.
- There are many complaints about the side effects of Trichopolum.
Fact. Side effects from taking metronidazole drugs are observed in more than half of patients. Most often these are nausea, vomiting, diarrhea, metallic taste in the mouth, local allergic reactions (in the vaginal area) and systemic (itching, rash, burning). Less commonly, more serious symptoms of the liver, nervous system, and blood counts. There are several ways to solve this problem:
- Discuss with your gynecologist the issue of prescribing an analogue drug based on the more modern and effective ornidazole from the same pharmacological group. Ornidazole can be used during pregnancy, it is much better tolerated - the incidence of side effects does not exceed 5%;
- if for any reason you need to use metronidazole preparations (material considerations, microflora susceptibility to metronidazole, etc.), I recommend using the alternative treatment regimen given in the subsection of the article on taking Trichopolum. However, reducing the duration of treatment automatically leads to an increase in dosage. Therefore, I would risk recommending this method only for treating a partner who does not have health problems. The expectant mother does not need such experiments with the liver;
- A worthy alternative to antimicrobial therapy with Trichopolum can be the homeopathic remedy Trichomonaden-Fluor-Inject. It is absolutely safe and has no contraindications.
DETAILS: Natural Analgesics: 8 Natural Remedies
In conclusion, I would like to wish expectant mothers to deal less with illnesses and think more about pleasant things. Be healthy!
Mechanism of action of trichopolum
The drug is used in the form of vaginal suppositories, tablets and solutions for intravenous injection. The tablets contain 250 mg of Metronidazole. For trichomoniasis, adults are prescribed 1 tablet 2 times a day after meals. Course - 10 days.
For the best effect and to avoid further infection, both sexual partners should undergo treatment at the same time. For amebiasis, tablets are prescribed after meals 3 times a day, duration of administration is up to 15 days.
Trichopolum - instructions for use for giardiasis: the daily dose for children under 5 years old is 1 tablet, from 6 to 10 years old - 375 mg/day, for adults - 2 tablets. The course of treatment is about 7-10 days. If necessary, the doctor may prescribe re-treatment in a month. For infections caused by anaerobic bacteria,
Trichopolum - instructions. Women are additionally recommended treatment with vaginal suppositories. Each suppository contains 500 mg of active substance. It is administered once a day at night. The recommended course is also 10 days. Before administration, the candle (it has the shape of a large white-yellowish tablet with rounded edges) must be moistened in boiled water. During menstruation, treatment is not stopped.
Metronidazole should be used in combination with other antibacterial drugs. Adults are prescribed 1 - 2 tablets 3 times a day during or after meals. Children under 12 years of age are prescribed a fractional dose of 7.5 mg/kg body weight, 3 times a day during or after meals.
To prevent infections, 4 tablets per day are prescribed. Then, on the doctor’s recommendation, the dose is reduced to 3 tablets per day. The drug is also taken during or after meals. Children – half a tablet 3 times a day. For newborns and children under 5 years of age, the dose of the drug is prescribed individually, and treatment is carried out under the strict supervision of a doctor.
Composition of Trichopolum
This medicine can be purchased in several release forms. But in any case, the composition of the main active components will be identical.
Often representatives of the fair sex are prescribed Trichopolum in the form of candles. This is a convenient form of release, which is also relatively safe, since it has a minimal effect on many internal organs, except for the problem area. Vaginal suppositories can be purchased in packages of 5 or 10 pcs. In addition, Trichopolum is sold in the form of tablets for oral and vaginal use. In rare cases, the drug is used in the form of a liquid, which can be purchased in ampoules or a bottle.
Regardless of the form in which this medicine is released, its basic composition will not change much. The main active component of Trichopolum is still metronidazole. In addition, the drug contains additional substances that enhance the effect of the main active element. With their help, metronidazole is easier to digest and easier to eliminate.
Additional components already depend on the form of release of the drug. If we are talking about Trichopolum in candles, then there will also be elements such as cellulose, silicon dioxide, povidone and stearic acid. Tablets, in addition to the main active substance, consist of starch, molasses, magnesium stearate and gelatin. Trichopolum, which is offered in solution, contains water, citric acid and sodium chloride.
special instructions
During pregnancy and lactation
Prescribing the drug is possible in the second trimester of pregnancy. When using the medication, careful supervision by a specialist is necessary. An allergic reaction may occur in a pregnant woman. In this case, the use of tablets must be stopped.
The active component of the drug passes into breast milk. For this reason, it is not recommended to use it during breastfeeding. As an alternative, it is possible to interrupt breastfeeding while using the drug. It will be possible to resume breastfeeding only 48 hours after the final insertion of the vaginal pill.
In childhood
Use in children is not recommended. As a last resort, the appointment is possible, but under medical supervision.
For liver dysfunction
In case of acute liver failure, treatment should be carried out under strict medical supervision.
In case of acute liver failure, treatment should be carried out under strict medical supervision.
For impaired renal function
In case of renal failure, complications in the patient are possible, so it is necessary to monitor the patient’s condition during treatment.
Precautions and contraindications
Absolute contraindications to taking the drug in tablet form and suppositories:
- hypersensitivity to the auxiliary components of the drug and intolerance to metronidazole;
- first trimester of pregnancy;
- breastfeeding period;
- pathologies of the nervous system.
The drug is not prescribed in large doses for liver failure. The tablets are contraindicated in children under three years of age. Suppositories are not used to treat children.
If kidney or liver function is impaired, you should consult a specialist about adjusting the dosage specified in the instructions for use.
Release form and composition
Available in several dosage forms.
Tablets are white with a yellowish tint. They have a flat and round shape, divided by a line. May turn yellow when exposed to light. Packed in blisters of 10 pieces. There are 2 blisters in 1 cardboard package.
Pills | 1 tab. |
Metronidazole | 250 mg |
Excipients: potato starch, gelatin, starch syrup, magnesium stearate. |
Solution for infusion is a clear liquid, yellow-green in color. Packaged in 20 ml clear glass ampoules and 100 ml polyethylene bottles.
Solution for infusion | 1 amp. or 1 fl. |
Metronidazole | 100 mg or 500 mg |
Excipients: sodium hydrogen phosphate, citric acid monohydrate, sodium chloride, water for injection. |
Vaginal tablets have an oblong biconvex shape and are white with a yellowish tint. Packed in blisters of 10 pcs. 1 tablet contains 500 mg of metronidazole and excipients: microcrystalline cellulose, povidone, crospovidone, colloidal silicon dioxide, stearic acid.
Description of the drug, release form
Trichopolum is a highly effective antibacterial agent. It has a detrimental effect on the reproduction of gardnerella, trichomonas, and lamblia. It also treats peptostreptococci, fusobacteria, and bacteroides. In addition, the drug is used for pathologies caused by anaerobic microorganisms. The main active ingredient of Trichopolum is metronidazole.
The medicine is available in various medicinal forms: suppositories, tablets, solution for injection. Vaginal suppositories and tablets are packaged in blister packs and cardboard boxes. The solution is available in dark glass ampoules, which are placed in cardboard packs.
Contraindications
In what cases is Trichopolum contraindicated for use?
- Individual intolerance to the active substance - metronidazole, any of its derivatives.
- Organic lesions of the central nervous system.
- Leukopenia.
- Liver diseases, including chronic failure.
- First trimester of pregnancy.
- Breastfeeding period.
- Children under three years of age.
It is allowed to prescribe Trichopolum in the second and third trimesters of pregnancy if the benefit to the mother outweighs the harm to the fetus. Metronidazole is able to cross the placenta. An overdose of Trichopolum causes increased side effects. The most common symptoms are nausea, vomiting, dizziness, and body weakness. If metronidazole poisoning occurs, symptomatic treatment is prescribed.
Is Trichopolum harmful during pregnancy?
This question worries all pregnant patients. Indeed, this drug is not recommended for expectant mothers. It is strictly contraindicated in the first trimester, due to the good absorption of metronidazole. The substance easily penetrates the membrane of the placenta. The component is harmful to the developing fetus and in the early stages can cause various disorders or lead to intrauterine death. Treatment is also prohibited during breastfeeding; the milk of a woman undergoing therapy is not suitable for feeding the baby.
In the second and third trimesters, taking Trichopolum is allowed, but with prior agreement with a specialist.
Situations where a woman took the drug without knowing about pregnancy require special consideration. In this case, the doctor may recommend an abortion for medical reasons: in the first three months, the baby’s body is formed, and drug intervention in the process often results in serious complications in the fetus. But expectant mothers should not despair: full formation begins approximately 20 days after fertilization. Usually by this time a woman notices a delay in menstruation and manages to stop taking medications.
Instructions for use
"Trichopol" is produced in the form of tablets for men and vaginal suppositories for women. In the second case, the tablet candle is freed from the contour cell and moistened with cooled boiled water. For trichomonas vaginitis, one tablet is inserted into the vagina, the course of therapy is seven days. For nonspecific vaginitis and bacterial vaginosis, one vaginal tablet is used per day for a week. It is allowed to combine the drug with oral tablets. The course of treatment is ten days, maximum repeated two to three times a year. If Trichopolum is used to treat trichomonas vaginitis in women and urethritis in men, sexual activity should be stopped for the duration of therapy.
For bacterial vaginosis, adults are recommended to take 500 mg - two tablets twice a day after meals for seven days. For trichomoniasis - 500 mg: two tablets twice a day for a week. This is the standard scheme. In each individual case, individual therapy for the diseases listed above is prescribed. For example, for pancreatitis in men, the daily dosage is 0.5 g, for exacerbation of the disease - 500 mg three times a day. The course of taking Trichopolum is individual.
Analogues of Trichopolum
The drug Trichopolum is available with a doctor's prescription. It is important to follow the rules of use regarding the course, dosage and frequency of administration. If you are intolerant to a component or excipients, have side effects, are unable to purchase the medicine for a course due to the high price, or other factors, you should discuss with your doctor what to replace Trichopolum with.
Analogs are cheaper than Trichopolum, indicating the price, release form and country of origin
Analogue | Release form | Price, in rubles | Manufacturer country |
Trichopolum | pills | 80-120 | Poland |
vaginal tablets | 290-400 | ||
Metronidazole | pills | 10-80 | Russia, Germany |
vaginal tablets | 150-250 | Russia | |
Tiberal | pills | 600-850 | Switzerland |
Flagyl | pills | 120-180 | France or Spain |
suppositories for intravaginal administration | 900-1050 | ||
Fluconazole | capsules | 10-80 | Russia |
Flucostat | 170-400 | ||
McMirror | pills | 900-1100 | Italy |
McMiror complex | vaginal capsules | 750-1100 | |
vaginal cream | |||
Klion | pills | 80-120 | Hungary |
Klion-D | vaginal tablets | 300-450 | |
Ornidazole | pills | 70-200 | Russia |
Terzhinan | vaginal tablets | 400-650 | France |
Tinidazole | pills | 40-90 | Russia |
Tiberal
The Tiberal analogue is produced by a Swiss pharmaceutical company in the form of tablets for oral administration. Refers to antibacterial drugs with antiprotozoal activity based on ornidazole. Dispensed by prescription. Prescribed for damage to tissues and organs by amoebas, lamblia, and trichomonas. Additionally used for prophylactic purposes before surgery.
Flagyl
An analogue of Trichopolum is the drug Flagyl. Sold by prescription, available in vaginal suppositories and tablets. Contains, like Trichopolum, metronidazole. Has the same indications, limitations and side effects. The cost of the analogue is more expensive. The frequency of adverse reactions is lower.
Fluconazole
A cheap substitute for Trichopolum is Fluconazole capsules with antifungal action. Produced by Russian pharmaceutical companies under the same trade name and by foreign manufacturers:
- Flucostat (Russia);
- Fluconazole-Teva (Israel);
- Diflucan (France);
- Mikosist (Hungary).
Fluconazole is produced in capsules of different dosages - 50 mg for children and 150 mg for adults. It is taken once, if necessary - again once a week or after 3 days for fungal infections of the skin, mucous membranes and organs (thrush, oral candidiasis, skin and nail fungus, etc.). Depending on the drug, the specifics of the release differ - with a prescription or without a form.
McMirror
The modern analogue of Trichopolum Macmiror is available in tablets and has antibacterial activity. Dispensed by prescription. It is used for bacterial infections, giardiasis, intestinal amebiasis and gastrointestinal diseases associated with Helicobacter pylori.
Pharmacies offer an analogue for intravaginal use - Macmiror Complex cream and suppositories. The composition contains the antibiotic nifuratel and the antifungal component nystatin. Macmiror has antiprotozoal activity. Sold by prescription, used as prescribed by a doctor for infections with bacteria, fungi, and protozoa.
Klion
An imported analogue of Trichopolum without side effects is Klion. Available in tablets. Contains metronidazole. It has the same indications and limitations as Trichopolum.
Another form of release is Klion-D vaginal tablets. In addition to metronidazole, they contain the antifungal component miconazole. Used for mixed vaginitis. If the pressing question is how to replace Trichopolum in gynecology, you can choose Klion-D for its combined composition and stronger therapeutic effect. The price of the analogue and Trichopolum is no different.
Which is better – Klion or Trichopolum, depends on the form of release. In tablets for oral administration, the drugs are identical in composition, properties and quality. An analogue of Trichopolum suppositories Klion-D is more effective because, in addition to metronidazole, it contains an antifungal component. It has three actions at once: antimicrobial, antiprotozoal and antifungal.
Tinidazole
The tablet analog Tinidazole, like Trichopolum, has antibacterial and antiprotozoal effects. It is used for gastrointestinal diseases associated with the bacterium Helicobacter pylori, giardiasis, amebiasis, and other diseases caused by protozoa.
It is impossible to say for sure which is better – Tinidazole or Trichopolum. Medicines are analogues, have the same spectrum of action and indications. They differ in the active substance.
Pharmacological action of Trichopolum
In accordance with the instructions for Trichopolum, the active ingredient of the drug is metronidazole. The excipients included in the tablets are magnesium stearate, starch syrup, gelatin, potato starch.
Trichopolum is a derivative of 5-nitroimidazole. The mechanism of action of the drug is due to the biochemical reduction of the 5-nitro group of metronidazole due to transport proteins of anaerobic protozoa and microorganisms. The reduced 5-nitro group interacts with the DNA cells of microorganisms, blunting the synthesis of their nucleic acids, which also leads to their death.
When used, Trichopolum is active against clostridia, fusobacteria, bacteroides, amoebas, balantidia, trichomonas and lamblia.
The drug does not have a bactericidal effect on most facultative anaerobes, bacteria, viruses and fungi. In the presence of mixed flora (anaerobes and aerobes), the drug exhibits synergism when combined with antibiotics that are active against common aerobes.
When used, Trichopolum increases the sensitivity of tumors to radiation, promotes sensitization to ethanol, and also activates reparative processes.
When taken orally, the substance is quickly absorbed from the gastrointestinal tract. Metronidazole has high bioavailability. Reaches maximum concentration in blood plasma after 1-3 hours. Poorly binds to blood proteins. According to the instructions, Trichopolum penetrates into seminal fluid, vaginal secretions, breast milk, abscess cavities, amniotic fluid, saliva, bile, brain, cerebrospinal fluid, skin, liver, kidneys and lungs. Metabolized in the liver. Excreted from the body through the kidneys. The period of complete elimination ranges from 12 to 24 hours.
Use of Trichopolum during pregnancy
Trichopolum should be used very carefully while expecting a child, especially in the 1st-3rd trimester. Gynecologists consider this particular period a contraindication, since the medication can adversely affect the development of the fetus.
In subsequent trimesters, this drug is recommended to be used only under the supervision of a leading physician.
During lactation, the use of Trichopolum is also not recommended, since its active component can be toxic to the baby, can provoke a disruption of its microflora and reduce overall immunity.
Metronidazole penetrates the placental barrier, therefore Trichopolum is contraindicated for use in the first trimester of pregnancy. The use of the drug in the second and third trimesters is possible only in cases where the expected benefit to the mother outweighs the potential risk to the fetus.
Since metronidazole is excreted in breast milk, reaching concentrations close to those in the blood plasma, if it is necessary to use Trichopolum during lactation, breastfeeding should be discontinued.
The active substance passes through the placenta and can damage the fetus, so prescribing Trichopolum in the first trimester of pregnancy is prohibited. In the second and third trimesters, administration is carried out according to the instructions, if the doctor has determined that the benefit for the mother exceeds the risk for the child.
In the first trimester, the use of Trichopolum is prohibited. During this period, the key organs and systems of the child are formed, and this treatment can cause irreparable harm to the baby. And in the second and third trimesters it can be used - in accordance with the doctor’s recommendations, of course.
In the first trimester of pregnancy, Trichopolum is not prescribed
The first trimester of pregnancy is characterized by the formation and formation of the internal organs of the unborn baby, therefore, to avoid the development of fetal abnormalities and the possibility of miscarriage, Trichopolum is not prescribed.
In subsequent trimesters of pregnancy, the appointment is possible if the condition of the expectant mother requires it, and it will not cause significant harm to the fetus.
When breastfeeding occurs, Trichopolum components may accumulate in breast milk; if indications for the use of Metronidazole arise, there is a need to interrupt breastfeeding.
It is not recommended to use the drug during pregnancy, especially not in the first trimester. Further, the drug is used only when the potential benefit to the mother is higher than the expected risk to the fetus.
It is also impossible to feed the baby with breast milk, since the active substance is transferred along with it. It is possible to continue feeding only 2 days after the last use of the drug.
Analogues of the drug trichopolum
Trichopolum can be replaced by products based on the same active ingredient or having similar antiprotozoal and antibacterial effects.
Analogues of the drug:
- Metrogyl: solution, tablets and gel based on metronidazole, used for infections, sepsis;
- Metronidazole: a tablet analogue of Trichopolum, used to treat infectious diseases;
- Flagyl: tablets and suppositories containing metronidazole are used for abscesses and vaginitis;
- Efloran: a substitute for Trichopolum for the treatment of protozoal infections;
- Gairo: an antiprotozoal drug in tablet format based on ornidazole, used in the treatment of trichomoniasis, giardiasis;
- Tiberal: tablets based on ornidazole, have an antiprotozoal effect.
What does the drug “Trichopol” help women with?
The drug is mainly prescribed for the treatment of infectious diseases and bacterial lesions of internal organs in women, namely:
- chlamydia;
- bacterial vulvovaginitis (also caused by gardnerella);
- colpitis;
- gonorrhea.
The drug in suppositories is prescribed for prophylactic purposes after surgery, as well as before the installation of an intrauterine device.
The drug in tablet form is used in the complex treatment of anaerobic infections of internal organs, the nervous system and inflammatory diseases of the joints caused by pathogens sensitive to metronidazole.
Suppositories act locally and are indicated for vulvovaginitis and bacterial infections of the vagina.
Trichopolum tablets are prescribed for the complex treatment of infectious diseases; they also help against diseases of the female reproductive system.
The drug is prescribed in the complex treatment of cystitis, including the chronic form, provoked by anaerobic microorganisms.
For prophylactic purposes, suppositories are indicated to minimize the risk of infection after termination of pregnancy.
Note! Metronidazole is not active against yeast-like fungi.
Indications for use
The action of Trichopol (as well as the biological fungicides trichodermin and trichocin) is based on the biochemical effect of microorganism proteins with the 5-nitro group of metronidazole. Bacterial cells inhibit (slow down) the synthesis of nucleic acids of the substance contained in the drug, and as a result die. Trichopolum simply kills pathogens (bacteria, protozoa).
This property is successfully used in dentistry in the treatment of mixed infections (Trichopolum is part of anti-inflammatory dental ointments), the drug is prescribed in the postoperative period, including after abortion, to prevent complications, and is actively used to eliminate a wide range of infections:
- giardiasis;
- trichomoniasis;
- Gardnerelez;
- osteomyelitis;
- stomach ulcer;
- gonorrhea;
- chlamydia;
- endometritis;
- meningitis;
- peritonitis;
- abscesses;
- cystitis;
- demodicosis;
- sepsis;
- sore throat, etc.
For women
What does Trichopolum help women with? In gynecology, this drug is used to treat inflammation caused by bacterial infections. Trichopolum is prescribed for cystitis, vaginitis (vaginosis), endometritis, colpitis, chlamydia, gonorrhea. The drug is effective in preparation for surgical treatment and in the postoperative period. Trichopolum during pregnancy is prescribed only after the first trimester, since metronidazole, which penetrates the placenta, can provoke fetal development disorders and intrauterine death.
For men
Because Trichopolum and alcohol are incompatible (the drug provokes allergies and worsening well-being), the medicine is used in the treatment of chronic alcoholism as a powerful “brake” that causes a persistent aversion to alcohol. What else does Trichopolum treat men for? In addition to diseases common to patients of both sexes, Trichopolum is effective in the treatment of infections and inflammation of the genitourinary tract caused by them:
- trichomonas urethritis;
- chlamydia;
- gonorrhea;
- amoebiasis;
- giardiasis;
- licheniasis;
- balantidiasis, etc.
For children and teenagers
The annotation stipulates that Trichopolum is prescribed only to patients over six years of age. In the treatment of children, this remedy is used for protozoal infections, for example, giardiasis, bacterial pneumonia, meningitis. The drug is effective in the treatment of cancer when infection is observed in the area of the tumor process. Trichopolum is used for the treatment of teenage acne caused by demodicosis, combining the use of tablets with the use of metronidazole-containing ointment.
Description
When applied topically, it has an anti-acne effect, the mechanism of which is precisely unknown (not related to the effect on the Demodex folliculorum mite, found in hair follicles and the secretion of the sebaceous glands, and any effect on the production of this secretion).
Metronidazole for external use may have antioxidant activity. It has been found that it significantly reduces the production of active oxygen, hydroxyl radicals and hydrogen peroxide by neutrophils, which are potential oxidants that can cause tissue damage at the site of inflammation.
Metronidazole for external use is ineffective against telangiectasias noted with rosacea.
Absorption is minimal; after external use of the gel, only trace amounts of the drug are found in the blood serum. Absorbed metronidazole passes through the placenta and the blood-brain barrier. Cmax – up to 66 ng/ml (when applying 1 g of gel, equivalent to 7.5 mg of metronidazole).
Pregnancy (first trimester), lactation period.
Apply a thin layer to previously cleansed skin 2 times a day, morning and evening, for 3-9 weeks. If necessary, apply an occlusive dressing. Application of cream and gel can be alternated. The average duration of treatment is 3-4 months, the therapeutic effect is usually observed after 3 weeks of treatment.
Hypersensitivity.
Rosacea (including post-steroid acne), acne vulgaris, infectious skin diseases, bedsores, trophic ulcers, burns, eczema, seborrheic eczema, oily seborrhea, seborrheic dermatitis, trophic ulcers of the lower extremities (against the background of varicose veins, diabetes mellitus) , slow-healing wounds, bedsores, hemorrhoids, anal fissures.
Allergic reactions (urticaria, skin rash); hyperemia, peeling and burning of the skin, lacrimation.
For external use only!
Do not apply to the mucous membrane of the eyes or near the eyes (may cause lacrimation). If the gel gets into your eyes, rinse them immediately with plenty of water.
It is important to apply the drug to the entire affected area.
Metronidazole for external use in the form of a gel is water-based, does not contain fat, is invisible on the face and does not leave stains.
When administered simultaneously, it enhances the effect of warfarin and other indirect antigoagulants (increases prothrombin time).
Trichopolum for demodicosis is used as part of complex treatment, as an antibiotic to combat infections associated with the disease. Trichopolum is active against Trichomonas vaginalis, Gardnerella vaginalis, Giardia lamblia, Entamoeba histolytica, obligate anaerobic bacteria (including Bacteroides spp., Fusobacterium spp.).
Contraindications
There is a group of people who cannot use Trichopolum for treatment. Taking the medication is contraindicated in the following cases:
- The first half of pregnancy, since the drug can be introduced through the placenta;
- During lactation. Metronidazole can accumulate in the milk of a nursing woman and threaten the well-being of the baby, so only if absolutely necessary can the mother take metronidazole, but at this point she will have to stop feeding milk;
- Blood diseases;
- Severe abnormalities in the central nervous system;
- Liver damage;
- Children under 3 years of age;
- Individual intolerance to the drug.
In case of liver failure, the concentration of metronidazole in plasma increases to dangerous levels.
Use metronidazole with caution in patients with kidney disease. If dizziness or problems with the gastrointestinal tract occur during treatment with it, therapy should be stopped
Interaction
Trichopolum ointment should be used with caution in tandem with lithium preparations. In this case, it is necessary to monitor the content of lithium and creatinine in the blood plasma. Doctors do not recommend simultaneous use of ointment with indirect anticoagulants. If their simultaneous use is necessary, it is important to constantly monitor the prothrombin time and determine the best dosage of the anti-clotting agent. You cannot use Trichopolum with Terfenadine and Astemizole. The medication can be applied no earlier than two weeks after the end of treatment based on Disulfiram.
Is it an antibiotic or not?
Yes, this drug is an antibiotic. Trichopolum belongs to the group of antimicrobial and antiparasitic drugs; the active ingredient is metronidazole. Once inside bacteria and protozoa, the drug changes its chemical structure, after which it interacts with the DNA of the microorganism and disrupts its synthesis.
Inhibition of DNA replication leads to cell death. Trichopolum is effective against protozoa, anaerobic bacteria, a number of gram-negative and gram-positive organisms (giardia, balantidia, gardenella, trichomonas, clostridia, fusobacteria, bacteroides, peptococci, etc.).
Action diagram
The action of Trichopolum is biochemical. The nitro group of the drug molecule is integrated into the respiratory chain of anaerobic and protozoan organisms, thereby disrupting their ability to breathe and causing death. In some varieties, Trichopolum also causes DNA degradation.
After administration, the medicine enters the gastrointestinal tract, where it is quickly absorbed. The efficiency is about 80%. The main substance (metronidazole) easily penetrates the tissues and fluids of the body, gradually concentrating in them. It accumulates, in particular, in breast milk, so taking the medicine is not recommended for nursing mothers: you should wait until the end of lactation or interrupt it prematurely.
Adverse reactions
If the recommended doses are observed, the drug Trichopolum is well tolerated by patients. In persons with increased individual sensitivity to Metronidazole, some side effects may occur:
- from the urinary system - pain during urination, inflammation of the bladder, polyuria, predominance of nighttime diuresis over daytime, change in urine color;
- allergic reactions - skin rash, itching, urticaria, erythema, swelling of the nose, rhinorrhea, fever, dermatitis;
- muscle pain and joint pain;
- from the digestive canal - lack of appetite, the appearance of a metallic taste in the mouth, stomach pain, nausea, vomiting, intestinal colic, bloating, increased gas formation, diarrhea, increased activity of liver transminases, reactive pancreatitis;
- from the nervous system - headaches, dizziness, ataxia, confusion, neuropathy, increased excitability, impaired coordination of movements, convulsions, drowsiness, in rare cases, hallucinations;
- leukopenia, neutropenia, thrombocytopenia, agranulocytosis.
If one or more of the listed side effects occurs, treatment with Trichopolum tablets should be stopped and consult a doctor for advice.
Side effects
After administration, the following side effects and undesirable effects may develop:
- Gastrointestinal disorders and diseases. On the part of the digestive system, side effects manifest themselves in the form of dyspepsia, flatulence, decreased appetite, up to complete refusal to eat, dryness of the mucous membranes of the oral cavity, inflammation of the tongue or oral cavity. Development of hepatitis and pancreatitis. Occurs in patients who have liver or pancreas diseases that occur in a latent form.
- Manifestations from the central nervous system. Undesirable effects on the nervous system occur in mild forms. Patients experience dizziness, headaches, insomnia and increased irritability. There are severe disorders, disturbances of consciousness, convulsions, hallucinations, and encephalopathy. These side effects account for less than 1% of adverse effects.
- Decrease in the number of blood cells. Some patients experience a decrease in the number of white blood cells, platelets, or red blood cells. This condition is temporary, but requires temporary discontinuation of the drug.
Side effects are extremely rare. They are more common in children, which requires careful use under the age of 10 years.
Instructions for use Trichopolum method and dosage
The method of application depends on the type of infection, and in each individual case it should be recommended by a doctor.
Tablets for oral administration are prescribed orally, during or after meals, the tablets are taken without chewing.
Trichomoniasis
Adults and children over 10 years of age are prescribed 250 mg (1 tablet) 3 times a day or 500 mg (2 tablets) 2 times a day for 7 days. An alternative treatment regimen is to prescribe 750 mg (3 tablets) in the morning and 1250 mg (5 tablets) in the evening or 2000 mg (8 tablets)/day once. The duration of treatment is 2 days. Treatment is carried out simultaneously for both sexual partners.
Children aged 3 to 7 years are prescribed 125 mg (1/2 tablet) 2 times a day; aged 7 to 10 years - 125 mg (1/2 tablet) 3 times a day. The course of treatment is 7 days.
Bacterial vaginosis
Adults are prescribed 500 mg (2 tablets) 2 times/day for 7 days or 2000 mg (8 tablets)/day once. Simultaneous treatment of the sexual partner is not required.
Amoebiasis
For invasive forms of intestinal amebiasis in susceptible patients (including amoebic dysentery), adults and children over 10 years of age are prescribed 750 mg (3 tablets) 3 times a day. Children aged 3 to 7 years - 250 mg (1 tablet) 4 times a day; at the age of 7 to 10 years - 375 mg (1.5 tablets) 3 times a day. The course of treatment is usually 5 days.
For amoebic liver abscess and other forms of extraintestinal amebiasis, adults and children over 10 years of age are prescribed 375 mg (1.5 tablets) 3 times a day. Children aged 3 to 7 years - 125 mg (1/2 tablet) 4 times a day; at the age of 7 to 10 years - 250 mg (1 tablet) 3 times a day. The course of treatment is 5 days.
IV administration
For the treatment of infectious diseases caused by anaerobic bacteria, adults and children over 12 years of age are prescribed the drug intravenously every 8 hours, 100 ml of a 0.5% solution (500 mg). The infusion is carried out at a rate of 5 ml/min. The maximum daily dose for intravenous administration is 4 g. The course of infusion therapy is 7-10 days, if necessary - 2-3 weeks. For children under 12 years of age, the dose for intravenous administration is set at the rate of 7.5 mg/kg body weight (1.5 ml of 0.5% metronidazole solution) every 8 hours. The drug is administered intravenously, slowly. Trichopolum is also prescribed orally in a single dose of 250-500 mg.
Vaginal tablets
- For trichomonas vaginitis, the drug is prescribed 1 vaginal tablet per day for 7-10 days in combination with taking metronidazole tablets.
- For nonspecific vaginitis and bacterial vaginosis, the drug is prescribed 1 vaginal tablet per day for 7 days, if necessary in combination with taking metronidazole tablets.
Treatment with metronidazole should not last more than 10 days and be repeated more than 2-3 times a year.
The vaginal tablet should be removed from the contour packaging, moistened with boiled cooled water and inserted deep into the vagina.
Trichopolum - application
Before taking Trichopolum, patients undergo a comprehensive examination. It is aimed at establishing the cause of the disease, its type and stage. These factors directly determine the type of Trichopolum dosage form used. Each case of the disease requires an individual approach, so the doctor prescribes the dosage and frequency of use of the medicine only after examination and careful study of the case of the disease.
Use of Trichopolum in gynecology
Trichopolum is often used in gynecology. This drug is effective against a number of pathogens, pathogens of the genital tract and urinary system. Such diseases are often accompanied by unpleasant painful sensations, which are easily eliminated by medicine. However, it is pointless to use Trichopolum for thrush: the drug is not effective against fungus and viruses. It is used for the following diseases:
- gonorrhea;
- trichomoniasis;
- vaginitis;
- endometriosis;
- colpitis
In most cases, the drug is used in the form of vaginal tablets. In this case, the medicine acts directly on the source of infection, quickly eliminates the symptoms of the disease and makes the patient feel better. The tablets are inserted into the vagina before bed or in the morning and evening if the medicine is prescribed twice a day.
Trichopolum for cystitis
Antibiotics are often used for cystitis of microbial origin. When the reproductive system is affected, the infection spreads to the urinary organs, which requires the use of antibacterial agents. Trichopolum is highly effective in detecting trichomonas cystitis and the spread of chlamydia to the area of the urinary system.
When prescribing the drug Trichopolum, the dosage is selected individually. More often, during the treatment of the disease, doctors adhere to the following treatment regimens:
- 250 mg of the drug 3 times a day;
- Course duration is maximum 10 days.
Trichopolum for sore throat
The drug Trichopolum is rarely used for diseases of the ENT organs. However, the drug has been found to be highly effective in the treatment of purulent tonsillitis. It helps to quickly relieve pain, relieve inflammation and wash away purulent plaque. However, some doctors have a negative attitude towards this medicine, arguing that metronidazole is ineffective for angina.
It only helps to wash away the purulent contents and relieve inflammation, but does not affect the cause of the disease. Given this feature, the drug is used as part of complex therapy for the disease. Tablets are prescribed at a dosage of 250 mg per day, 3-5 days in a row. The dosage and frequency of administration are individual, so taking the medicine yourself is unacceptable. When telling what Trichopolum treats, throat diseases are not indicated.
Trichopolum for worms
The drug is effective against Giardia. These parasitic microorganisms are common in the external environment. Infection occurs through consumption of food and water contaminated with parasites. Lack of heat treatment increases the risk of Giardia infection. In most cases, the pathology affects preschool children due to frequent violations of hygiene rules. Infection occurs:
- when playing in the sandbox;
- due to the habit of biting nails;
- when placing dirty toys in the mouth.
To determine how to take Trichopolum for a patient with worms, doctors pay attention to his age. In this case, adhere to the following dosages:
- from 3 to 7 years – 250-375 mg of the drug per day for 5 days in a row or 500-750 mg once a day for 3 days;
- 7-10 years – 250 mg 2 times a day for 5 days or 1000 mg 1 time a day for 3 days in a row;
- children over 10 years of age and adults - 2 tablets 2 times a day for 7 days or 2000 mg 1 time a day for 3 days in a row.
Trichopolum for acne
When telling patients what Trichopolum treats, dermatologists also name some skin diseases. The drug is effective against acne caused by demodicosis. The disease is caused by demodex mites. Certain conditions are necessary for its mass reproduction and development of inflammation. In most cases, the trigger is hormonal changes associated with the maturation of the reproductive system in adolescents.
Trichopolum for demodicosis is prescribed by dermatologists taking into account the severity of the disease and its stage. In most cases, doctors adhere to the following scheme:
- 1 tablet 2 times a day for 10 days;
- Metronidazole gel - on the area of the rash twice a day.
Drug interactions
Metronidazole, interacting with anticoagulants from the coumaron series, is doubly effective, but the dose in this case should be reduced by 2 times. Taking metronidazole may cause a negative reaction after taking ethanol. Negative neurological reactions may occur if the dosage interval with disulfiram is not observed. It must be at least 14 days.
Cimetidine enhances the concentration of metronidazole in the blood. This may cause side effects. On the contrary, phenobarbital and phenytoin accelerate the metabolism of the drug and remove it from the body faster. Trichopolum does not combine with vecuronium bromide. Sulfonamides help accelerate the destruction of microorganisms by metronidazole.
Interaction of Trichopolum with other drugs
- The active substance increases the activity of Warfarin and other coumarin anticoagulants. If such a combination of drugs is used, the dosage of both drugs will be reduced.
- The metabolism of metronidazole is suppressed by cimetidine, which leads to an increase in the concentration of the first substance in the blood and increases the risk of side effects.
- While taking Trichopolum and lithium preparations, the level of the latter substance in the blood system increases, which leads to intoxication of the body.
- Drugs that stimulate the activity of liver enzymes (Phenytoin and Phenobarbital) reduce the activity of metronidazole.
- Trichopolum may increase the concentration of Cyclosporine in the blood when these drugs are used in combination.
- Metronidazole should not be combined with Vecuronium bromide, a non-depolarizing muscle relaxant.
- Trichopolum reduces the clearance of Fluorouracil, which increases the toxic effect on the body of the latter drug.
- Metronidazole tends to increase the plasma concentration of Bisulfan.
- The bactericidal effect of Trichopolum is enhanced by sulfonamides.
- The interaction of metronidazole and disulfiram leads to the development of neurological disorders, so the distance between the use of these drugs should be at least two weeks.
Trichopolum vaginal suppositories should be stored at room temperature (no more than 25 degrees) in a dry place, protected from sunlight.
Trichopolum for demodicosis and other causes of acne
Subcutaneous mites from the genus Demodex quickly spread in the skin, releasing their toxins, causing irritation and acne. Metronidazole penetrates the parasite's body and destroys it at the cellular level. Doctors often prescribe acne tablets Trichopolum for demodicosis, but first specialists must make sure that acne is actually caused by mite activity. To do this, the patient's skin is scraped and the microflora is examined.
Hormonal changes during adolescence are common. This results in immune deficiencies and problem skin. Trichopolum can help correct the situation if you take the medicine in accordance with the rules (on the recommendation of a doctor and in accordance with the instructions). Even during this same period, ointments for demodicosis are used externally.
Diseases of the gastrointestinal tract are considered one of the main causes of acne. Most often, with digestive disorders, it is not just single pimples that occur, but constant rashes. Abscesses, nodes and cysts often develop. When it is precisely established that the cause of skin imperfections is infectious lesions of the gastrointestinal tract, doctors can prescribe oral administration of Trichopolum tablets.
For an acne mask with trichopolum, take 2 tablets, crush them, add a pinch of baby powder and boric acid. Dilute the powder with a small amount of pharmaceutical solution of hydrogen peroxide to obtain a thick paste. The mixture is applied to the face with a cosmetic brush, and when completely dry, simply shake off the white powder.
Chatterboxes are made from drugs containing metronidazole by mixing various components:
- 6 tablets of trichopolum;
- 6 tablets of streptocide;
- 6 mummy tablets;
- 100 ml unflavored vodka.
All solid ingredients are mixed with vodka. Metronidazole and streptocide do not dissolve, so the mixture is shaken before each use to treat acne. The product is applied with a cotton swab or disk to the affected area. Usually use the mash in the evening and leave it overnight. In the morning, just wash your face and wipe your face with antibacterial lotion.
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Incidents with genitourinary problems
Trichomoniasis in men manifests itself as urethritis and cystitis. Women complain of “feminine” problems (itching, vaginal discharge, heavy periods), pain when urinating. It is necessary to contact a specialist in the gynecology department. The doctor treats the disease, taking into account all the effects of the medication, indications for taking the medication, and side effects. Trichopolum for cystitis (or analogues) begin to be taken after diagnosis. The doctor treats both sexual partners for 5-7 days.
You should take 250-500 mg of Trichopolum by mouth 2-3 times a day. At the same time, women use vaginal suppositories of 100 mg or vaginal tablets of 500 mg once, inserted into the vagina at night, for a total of 6 days. If there is no effect, the test results remain poor (reviews say that this is not uncommon), such treatment alone is considered insufficient.
There are indications for repeating a course of medication (orally according to the same scheme, in women additionally vaginal suppositories) for up to 14 days. These suppositories, when used for a long time, have side effects in the form of fungus. The following symptoms are noted:
- In the vagina there is a burning sensation, pain, redness, swelling of the mucous membrane.
- White cheesy discharge is visible on the mucous membrane. The instructions for use also warn about this.
Trichopolum for thrush (or its analogues) is immediately canceled. An antifungal antibiotic is urgently prescribed locally, which is best done by a doctor. There is no point in taking Trichopolum for thrush, even if you feel better. Sometimes an antifungal antibiotic is recommended to be taken by mouth. The specialist decides whether or not there are indications for such an action.
Analogs
Is it worth replacing Trichopolum with other drugs similar to this? The objective advantages of the drug in question include high bioavailability compared to similar medications. Trichopolum quickly reaches a high concentration in the body, so the effect of treatment occurs faster. In addition, it is produced in several forms: tablets, suppositories, solution for intravenous administration.
Analogues of Trichopolum include the following drugs:
For example, Metronidazole has the same benefits as Trichopolum, but it is also available in the form of a gel and cream for external use. However, compared to other analogues, Metronidazole has low bioavailability. The cream effectively treats acne, pimples, erythema, and various inflammatory processes. Apply the cream in a thin layer to damaged skin twice a day and rub in with light movements. The course of such treatment ranges from two to four months.
To whom and when is Trichopol not prescribed?
This drug is not prescribed for those with an individual sensitivity to metronidazole or its other components, as well as for head injuries and the following diseases:
- leukopenia;
- liver failure (in large doses);
- pathologies and organic lesions of the brain and central nervous system (including epilepsy);
- blood diseases.
Trichopolum is not prescribed to children under 3 years of age. It is also contraindicated for pregnant women in the 1st trimester and during breastfeeding, since metronidazole can penetrate into the embryo through the placental barrier, and after the birth of the baby into breast milk. It is prescribed only when absolutely necessary, if the expectant mother urgently needs to be treated. In this case, the woman’s life is more important than the possible risk of complications in the fetus. In the 2nd and 3rd trimester of pregnancy, the medicine is prescribed, but with caution.
Vaginal gels and creams, suppositories and tablets with metronidazole during pregnancy and breastfeeding are not contraindicated, since from these pharmaceutical forms it is not absorbed into the general bloodstream and does not penetrate the uterus or breast milk.
Contraindications to the drug
Let's figure out what Trichopolum ointment treats. The drug has proven effective in the treatment and prevention of anaerobic infections during surgery, as well as complex therapy of mixed aerobic-anaerobic infections.
- gas gangrene;
- acne;
- infectious diseases of the skin;
- sepsis;
- infections caused by microorganisms that are sensitive to the drug;
- sexual infections, etc.
In addition, the ointment can reduce the population of parasites on the skin, causing the death of individual adults and even larvae. Also, the drug can significantly reduce the production of sebum, remove inflammation, redness and swelling of soft tissues. Trichopolum ointment is actively prescribed by doctors to minimize itching sensations. In addition to all of the above, the product accelerates cell regeneration and the healing process of damaged skin.
The main contraindication for treatment with Trichopolum is individual intolerance to the main component - metronidazole. It is also prohibited to use the drug for disorders of the central nervous system, during lactation and pregnancy up to twelve weeks, and in case of insufficient liver and kidney function. According to the instructions, Trichopolum ointment is contraindicated for children under five years of age.
Every patient using Trichopolum should be aware of its incompatibility with alcoholic beverages. The medicine causes an aversion to ethyl alcohol.
This property is successfully used by narcologists in the treatment of alcoholism.
Particular care must be taken when treating demodicosis and other diseases in parallel. Trichopolum does not combine well with some drugs (disulfiram, cimetidine, vecuronium bromides).
You should avoid Trichopolum in any form if:
- bearing a child and breastfeeding;
- kidney and liver diseases (this contributes to the accumulation of the drug in the body, which is unsafe for health);
- individual intolerance to individual components of the drug (primarily allergy to metronidazole);
- disorders of the central nervous system;
- low production of leukocytes, etc.
Why is the drug banned for pregnant women?
The main active ingredient, metronidazole, can have a negative effect on the fetus and also impair the taste of breast milk. Also, treatment with Trichopolum is not practiced in children under 6 years of age.
Common side effects include:
- local redness of the skin and itching after applying the ointment (as an allergic reaction); If severe intolerance occurs, anaphylactic shock occurs;
- changes in blood composition (decrease in the number of red blood cells and platelets);
- impaired coordination in space;
- mild dizziness;
- decreased visual or hearing acuity;
- general lethargy, decreased concentration, drowsiness;
- development of stomatitis;
- dyspepsia, nausea;
- appearance of the first signs of pancreatitis.
The appearance of at least one of the side effects is a good reason to consult a doctor to adjust the treatment or change the drug.
Common analogues of Trichopolum are Metrogyl and Flagyl gels, ornidazole tablets.
Why does Trichopolum help, why is it prescribed, and how much does this drug cost? The medicine Trichopolum is prescribed to combat protozoal infections. Most often this is trichomonas vaginitis in women and urethritis in men. The use of the drug for trichomoniasis is an effective method for treating the infection.
DETAILS: Ointment for weeping eczema - Allergies
Trichopolum can also be used for infections such as bacterial damage to bones, joints, brain, inflammation in the pelvic organs and heart muscles.
What does Trichopolum treat besides the listed ailments? It is used for duodenal ulcers or stomach ulcers. The gastrointestinal tract can be infected by the bacterium Helicobacter pylori, which is not able to fight the active substance of the drug metronidazole.
But not all bacteria and fungi can be eliminated by metronidazole. For example, for thrush, this active remedy is not used, since Trichopolum does not fight Candida fungus.
What else does the drug treat? The drug Tripohol is also used in surgery. This is done for preventive purposes, to prevent complications after surgery.
The use of the drug is also possible for chronic alcoholism. The interaction of the main substance metronidazole with ethyl alcohol leads to the fact that the human body is not able to tolerate alcoholic beverages, as its sensitivity to alcohol increases.
According to the instructions, Trichopolum has contraindications. The drug is prohibited if the person is sick:
- leukemia;
- damage to the central nervous system;
- renal failure;
- hypersensitivity to metronidazole;
- liver failure.
Pregnant women are advised to limit treatment with Trichopolum. In the middle and end of pregnancy, it must be used with extreme caution, and the course of treatment is carried out under the supervision of a doctor. When breastfeeding and in the first months of pregnancy, the use of Trichopolum is prohibited.
What does this remedy treat? Trichopolum is used to treat specific bacterial infections. Its action includes penetration into the bacterial cell and an effect on some of its components, as a result, the bacteria die. It is used in gynecology (for inflammation, trichomoniasis), for cystitis, giardiasis (giardia), stomach ulcers, gastritis.
In combination with amoxicillin, trichopolum is useful against Helicobacter pylori. Amoxicillin inhibits the development of Helicobacter pylori resistance to metronidazole. Trichopolum is particularly effective against anaerobic bacterial infections, and is also used to treat Crohn's disease, antibiotic-associated diarrhea, acne and rosacea.
Taking Trichopolum is strictly contraindicated in patients with a previous case of hypersensitivity to metronidazole or other nitroimidazole derivatives; for blood diseases, pregnancy and lactation, sensitivity to metronidazole and liver failure.
After taking Trichopolum, it is advisable to take a course of bifidolactobacteria to restore the intestinal microflora. Since Trichopolum is an antibiotic, drinking alcohol during treatment and for several days after is prohibited, serious consequences are possible.
Dosage regimen
Trichopolum ointment for demodex and other skin pathologies is applied with smooth movements to the affected areas. You should not press hard or rub the drug. The ointment is quickly absorbed, does not roll off on the skin and does not cause any inconvenience when used in everyday life. The dosage is determined only by the attending physician, but most often the drug should be applied twice a day. The duration of the course of treatment is from thirty to forty-five days. In advanced cases, it is repeated after 2-2.5 months.
Trichopolum price
Approximate prices in capital pharmacies:
Name | Manufacturer | Price on the Internet, rubles | Price at the pharmacy, rubles |
Tablets 250 mg 20 pcs. | Poland | 91 | 100 |
vaginal 500 mg 10 pcs. | 293 | 310 | |
Tablets 250 mg 20 pcs. | Akrikhin | 74 | 85 |
vaginal 500 mg 10 pcs. | 272 | 300 | |
Solution 0.5% 100 ml | Poland | 122 | 150 |
What does Trichopolum treat?
Trichopolum belongs to the category of pharmacological agents used to treat pathologies of infectious-inflammatory origin, provoked by pathogens with sensitivity to the drug. The main indications for the use of Trichopolum:
- Vaginosis of bacterial nature.
- Nonspecific vaginitis, other gynecological diseases.
- Trichomoniasis.
- Giardiasis.
- Infections caused by the bacterium Helicobacter pylori.
- Peritonitis.
- Hepatic and intestinal amebiasis, which occurs in severe form.
- Gas gangrene.
- Abscesses in the brain, pelvis or other internal organs.
- Sepsis.
Trichopolum - what does it treat? This question arises for many patients who are prescribed this pharmacological drug. The instructions from the manufacturer emphasize that the drug is widely used in the treatment of many gynecological pathologies caused by microorganisms sensitive to Trichopolum. The pharmacological drug belongs to the group of nitro-5-imidazoles with pronounced antiprotozoal and antibacterial properties. Trichopolum actively affects the DNA of the cells of microorganisms that are causative agents of infectious and inflammatory diseases. This leads to their gradual destruction.
Why do narcologists use
The use of Trichopolum for the treatment of alcoholism is based on an “interesting” combination when Trichopolum and alcohol become incompatible. When consuming ethanol, signs of poisoning by the toxic products of its incomplete decomposition (acetaldehyde) develop. Subjectively, this condition is difficult to tolerate, causing a conditioned reflex of aversion to drinking drinks that contain ethanol.
For successful treatment, one condition is necessary - the person must have the desire to stop drinking alcohol. Regular use of Trichopolum takes at least 6 months under medical supervision. Start taking 500 mg 1 time per day after meals for 3-4 days (2 tablets of 250 mg).
If the drug is well tolerated, take 500 mg tablets 3 times a day for the next 10 days (2 tablets of 250 mg), sometimes adding another 250 mg to each dose. Then the dosage is reduced to the original 500 mg (or another 250 mg is added to it). This regimen is continued for six months, and periodically the doctor recommends alcohol tests.
How to use trichopolum to treat acne
Different types of infections provoke inflammatory phenomena in the body that negatively affect the skin. Trichopolum rids the body of many parasites, but sometimes it turns out to be ineffective against microbes that live on the surface and inside the pores of the skin - fungi, staphylococci and streptococci. This is one of the good reasons why trichopolum should be taken only after consultation with a dermatologist.
You can find in pharmacies a large number of a wide variety of dosage forms of metronidazole - for oral administration, local therapy, intravenous, rectal, intravaginal administration. As for the treatment of acne vulgaris and rosacea with Trichopolum tablets, instructions for use against acne are contained in each package.
How to take Trichopolum for acne:
- The drug is taken orally 3-4 times a day.
- The daily dose is 500 mg (2 tablets).
- Take the medicine during or after meals.
- Treatment lasts on average 5–7 days, but no more than one week.
Price and reviews
Sveta, 23 years old
Those who have used the drug in pills complain of its side effects. According to reviews, these pills harm the liver and taste bitter. The positive aspects include the cost of the drug. While there are many positive reviews, there are also negative ones, where patients who used the drug report that it did not give any results.
As for vaginal suppositories, they dissolve very poorly in water. There are negative reviews regarding the lack of results in the treatment of thrush with Trichopolum, as well as other infectious diseases. The positive aspects include the cost of the drug.
In general, reviews of Trichopolum ointment are good from both doctors and patients. Many note that side effects do not always appear, and with a short course of treatment they are usually absent altogether. Since metronidazole, which is part of the ointment, is effective against a wide range of pathogenic bacteria, a single treatment for 7-10 days can relieve several diseases simultaneously.
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Use of Trichopolum for bacterial vaginosis
This is one of the most common gynecological diseases. Bacterial vaginosis is called dysbiosis of the vaginal flora, caused by suppression of the growth of lactobacilli, which make up more than 95% of healthy microflora, and a strong increase in opportunistic bacteria, mainly gardnerella.
Treatment of this disease is carried out in 2 stages. First, the multiplied opportunistic bacteria are destroyed, which is why Trichopolum is prescribed.
Take Trichopolum for bacterial vaginosis:
- once 8 tablets. for only 1 day;
- 2 tables each 2 times a day, but for 1 week.
Treatment regimens
Demodicosis requires long-term therapy. This is due to the fact that the parasite larvae can penetrate into the deep layers of the skin. Therefore, antibacterial components will take a long time to act on them.
Treatment with Trichopolum involves the use of tablets containing 250 mg of the active substance. One tablet is taken three times a day.
The duration of therapy is determined depending on the severity of the disease, as well as the individual characteristics of the patient. First, a course is prescribed for 21 days. If no positive result is observed, then therapy can be extended after a week's break.
Internal administration of Trichopolum turns out to be extremely important for the treatment of demodicosis. After all, the drug:
- has an immunomodulatory effect;
- eliminates tissue swelling;
- eliminates the inflammatory process.
It is important to carry out comprehensive treatment. Therefore, Trichosexual ointment for demodicosis is additionally prescribed. In addition, analogs with metronidazole are used in the composition - Klion and Metrogyl gels. They must be applied to the skin for 14 days.
Composition, action
Trichopolum is highly active against:
- gonococci;
- trichomonas;
- cocci.
Also effective against anaerobic microorganisms and some gram-positive pathogens. This drug is powerless against fungal infections, but can be prescribed by a doctor as part of complex therapy.
The tablets contain the active substance metronidazole (500 mg). Additional components:
- stearic acid;
- gelatin;
- povidone;
- starch syrup;
- potato starch;
- microcrystalline cellulose.
Vaginal tablets Trichopol (500 mg) are white with a yellow coating, elongated, biconvex.
Composition of vaginal tablets:
- metronidazole
- microcrystalline cellulose;
- crospovidone;
- povidone;
- stearic acid.
All these components provide the proper therapeutic effect: the DNA of the bacterium is disrupted, which leads to its death, and as a result, the person recovers.
Trichopolum begins to act within 3 hours after administration.
Cost and terms of dispensing from pharmacies
The ointment should be stored in a place inaccessible to small children. It must be reliably protected from direct sunlight. The ambient temperature should not exceed 25 degrees.
The drug is dispensed in the pharmacy only with a doctor's prescription. The price of Trichopolum ointment ranges from 90 to 100 rubles.
In principle, it is recommended to use Trichopolum for making simple talkers, which can be made and used at home. There are several basic recipes.
Recipe one
You will need one bottle of salicylic alcohol, four tablets of chloramphenicol and four tablets of trichopolum. All tablets must be crushed into powder and filled with alcohol. After which, before applying the mash to the skin, the container is thoroughly shaken. It is recommended to apply the mash twice a day, morning and evening. As a rule, a week is enough to relieve inflammation on the skin, and another 15 days for complete restoration of the skin.
Recipe two
Here, in the preparation of mash, 100 grams of vodka, six mummy tablets and six tablets each of streptocide and trichopolum are used. The tablets must be thoroughly crushed and added to vodka with mumiyo. Before applying to the skin, the shaker is shaken. Here the principle of application is to wet the pimples once a day, before going to bed.
Recipe three
250 grams of medical alcohol, or you can use the same volume of vodka, and four Trichopolum tablets. Trichopolum tablets should be crushed into powder, after which they are filled with alcohol or vodka and infused for three days.
After this, you can apply the mash to problem areas of the skin. Moreover, it is the area of the rash that needs to be treated, and not the surrounding tissue. You should use the mash once a day, at night, and in the morning you will need to apply a moisturizer to the skin; the composition of the mash seriously dries out the skin.
Special Recommendations
This pharmaceutical drug is prescribed with caution to people with liver pathologies and disruption of the proper functioning of this organ. Treatment with a drug can lead to an increase in the level of the main active element in the plasma, as a result of which the risk of developing adverse reactions increases.
Particular caution is required when using the drug "Trichopol" in patients with pathologies of the nervous system or impaired hematopoietic functions. The occurrence of dizziness and excessive weakness during the treatment period requires immediate discontinuation of the drug and consultation with a doctor.
If it is necessary to use the drug "Trichopol" for more than 7 days, it is recommended to take a blood test in order to monitor the peripheral blood picture and liver functionality.
When treating trichomoniasis with this medication, both sexual partners should be treated and should abstain from sexual intercourse at this time. After completing the therapeutic course, you should definitely conduct control laboratory tests and take smears from the cervical canal and urethra three times (before and after menstruation, once a month).
When treating giardiasis, there is a need to conduct control stool tests a month after completion of therapy at intervals of several days.
When treating with tablets, it is recommended to avoid alcoholic beverages, as this can lead to toxic damage to the digestive and urinary systems.
During therapy, the patient's urine may be dark brown, which is not considered a pathology and is due to the presence of a water-soluble dye in the medication.
The medicine is not prescribed for the treatment of children under 3 years of age due to the lack of clinical experience and unknown safety. Tablets are not recommended to be combined with antibacterial drugs or sulfonamides for the treatment of diseases under the age of 18 years due to the high likelihood of side effects from the liver and nervous system.
Patients over 65 years of age require individual selection of the dosage of the drug.
During the treatment period, you should refrain from driving vehicles and equipment that require high concentration.
Is Trichopolum effective against helminths?
Many patients believe that metronidazole, the active ingredient in the drug, can be used for worms. Indeed, such a practice is applicable in parasitology, but it has no scientific basis.
Trichopolum is prescribed for mixed infestations and serious helminthiasis, as an additional remedy that enhances the effect of basic medications.
Metronidazole successfully destroys Trichomonas and other protozoa, which, as a result of their vital activity, provoke the death of healthy tissue. It is these that some worms feed on, and the death of microorganisms becomes the cause of their death by starvation. However, Trichopolum cannot be used as the main anthelmintic drug.
Why is Trichopolum prescribed?
Demodicosis is a disease that occurs in a chronic form. When it occurs, damage is noted not only to the integument, but also to the eyes. Often the first symptoms include:
- tearfulness;
- redness of the eyes;
- skin rashes.
The changes do not go away even with treatment with any cream. And even if you manage to cope with the pathology, negative signs appear again after a while.
The drug not only eliminates the parasite, but also fights pathogenic microflora
It is necessary to influence the tick both locally and systemically.
The patient is prescribed therapy:
- antiseptic Dimexide;
- Ichthyol and Zinc ointments;
- Spregal spray;
- Blepharogel;
- cholinergic drugs.
The systemic effect is antibacterial and antiparasitic. This is Trichopolum or its analogue Metronidazole. When treating demodicosis, they eliminate tick-borne microorganisms and also fight opportunistic bacterial flora.
Trichopolum - a remedy for parasites of the skin and the whole body
The highly active drug is widely used to treat infections caused by certain protozoa and bacteria. In reviews of Trichopolum for acne, they often write that it is not an antibiotic, so it is not addictive. Metronidazole is a synthetic substance, and the first antibiotic, penicillin, is of natural origin (from a mold). The active ingredient has a bactericidal effect, penetrates bacteria and acts on DNA and proteins. The synthesis of these important compounds is disrupted and the microbial cell dies.
Metronidazole is a chemical antibacterial drug that quickly acts on microorganisms that are sensitive to it. The effect can be cytotoxic (kills bacterial cells) or cytostatic (stops the activity of microbes). Inflammation of the sebaceous glands is provoked by Propinibacterium acnes, yeast fungi and Demodex mites. All of them contribute to the formation of acne vulgaris, rosacea, and oily seborrhea.
Metronidazole-based antimicrobial agents:
- Tablets “Klion”, “Metranidazole”, “Medazol” - more than 30 trade names in total.
- Gels “Metrogil”, “MetrogilDenta”, “VidmerNidaza”.
- Cream "Rosex".
The listed medications are widely used to treat aerobic-anaerobic infections. Metronidazole relieves pathologies of the gastrointestinal tract, skin, central nervous system, respiratory tract and genital organs.
Action and rules for using Trichopolum
For demodicosis, Trichopolum is prescribed as part of a complex therapy consisting of drugs that act on the causative agent of the disease and local antiseptics, which help consolidate the result.
The action of the drug is based on a direct effect on the basic vital processes of demodexes, which ultimately kills them. In particular, Trichopolum suppresses the synthesis of ribonucleic and deoxyribonucleic acids. In addition, the medicine also affects bacterial microflora, which negatively affects the epithelium.
Thus, the following aspects can be distinguished in the action of Trichopolum:
- disinfection of the surface of the skin and its internal layers
- tightening and drying of inflamed areas
- destruction of demodexes
- partly – relieving inflammation and swelling
The drug is used in different ways depending on the severity of the disease. The most commonly used therapeutic methods for demodicosis using Trichopolum:
- Ointment. Prepare by crushing 2-5 tablets of the drug and mixing them with a moisturizing, hypoallergenic skin cream. Apply the product in a thin layer to previously prepared skin (rinsing or disinfection). Frequency of use – 2 times a day. The course of therapy is up to 2 months, after which a 2-week break is taken.
- Oral tablets. Since Trichopolum is available in this form, no preparation in this regard is required for its use. To treat demodicosis, use 1-2 tablets daily for 7-10 days. Reducing or increasing the dosage and course of therapy occurs only after consultation with a dermatologist. It is important to take the tablets during or before meals with plenty of fluids.
Other forms of Trichopolum are used only in accordance with their instructions and exclusively as prescribed by a doctor.
Possible contraindications and side effects
Trichopolum is not a drug that can boast of portability in terms of use. The fact is that the specificity of this medication creates a huge number of contraindications for it.
Given this feature of the drug, it should be treated through its use without ignoring the basic rules of such therapy. One of the main rules is compliance with contraindications to the use of Trichopolum.
Today it is prohibited to use metronidazole-based medications for:
- pregnancy and lactation, since the substance can adversely affect the development of the fetus
- allergies to medication components
- serious damage to the liver and kidneys
- under 3 years of age
- pathologies of the central nervous system and cardiovascular
- course of therapy with Amoxicillin
Ignoring contraindications in relation to Trichopolum is unacceptable. By violating current standards, naturally without permission from a dermatologist, the risks of causing harm to health are very high. Is it worth it? Of course not. After all, the modern pharmacological market is rich in various medications that can act in a similar way to Trichopolum, but at the same time without so many contraindications.
By ignoring the rules for using the drug, any person risks experiencing a whole list of side effects.
Among which are often manifested:
- nausea, vomiting or constipation, diarrhea
- headache and dizziness
- sleep problems
- increased “depressive” moods
- hearing impairment
- anemia
- decreased levels of white blood cells and platelets in the blood
- discomfort in muscles and joints
- cystitis or other urinary problems
- allergic reaction
In general, the “side effects” of Trichopolum are by no means harmless, so you should not allow them to appear.
Advantages and disadvantages of treatment with Trichopolum
Summarizing today's material, let's note the main advantages and disadvantages of getting rid of demodicosis using Trichopolum.
Let's start by considering the advantages of using the drug, among which are:
- Firstly, the effect of the medicine is quite good. Of course, it will not help get rid of the most serious manifestations of demodicosis, but it will cope with moderate and mild severity of the disease.
- Secondly, the price of the drug is “ridiculous”. It's not expensive at all.
- Thirdly, the functionality of the application. That is, the possibility of using the drug in a variety of forms: tablets, masks, scrubs, creams, ointments, suppositories and the like.
Among the disadvantages of Trichopolum there are also some provisions, or rather one thing - the presence of a considerable number of contraindications, which cannot in any way characterize the drug on the positive side. Otherwise, the drug shows itself exclusively on the positive side and can only be recommended for use.
This is probably all for Trichopolum. We hope the material presented today was useful to you. Good health to you!
diagnosislab.com
Why do dermatologists and cosmetologists use
Trichopolum for acne (like its analogues) successfully treats demodicosis of various forms, and is part of the products used for “deep” skin lesions. The summary for the drug specifies that it does not act on ticks, but reviews indicate its effectiveness. This fact is explained by the fact that:
- Ticks carry microbes into the deep layers of the skin, creating favorable conditions for the life of bacteria.
- Microbes located on the surface of the tick increase its activity.
- A decrease in immunity caused by anaerobic flora of the intestines, liver, and bile ducts activates the activity of skin mites. Indications for the use of Trichopolum or its analogues are becoming obvious.
The treatment regimen is determined by the doctor after examination. The severity of demodicosis and accompanying human diseases are taken into account. Standard actions include a combination of general and local use of Trichopolum.
Taking the drug orally for 2-4 weeks, 250 mg 3 times a day, eliminates infectious lesions of internal organs, which helps improve human immunity. Externally, the skin is treated with ointment or gel, which includes Trichopolum (the analogue names Klion, Metrogyl are more common). This ointment or gel contains 2% Trichopolum.
For purulent rashes, an antibiotic is simultaneously prescribed, taking into account compatibility. Reviews about this treatment are very different. Sometimes, due to side effects, they stop taking the drug earlier without getting the desired result. Other reviews describe stopping the use of Trichopolum on your own due to the rapid elimination of the visible problem.
If there is no effect from such actions, other combined techniques are used. For example, dermatologist L. R. Beridze (2009) suggests cryotherapy and treatment of affected skin with Rosamet cream (contains 1% Trichopolum). It has been proven that the destruction of ticks during demodicosis does not guarantee recovery, but is often the cause of the development of chronic forms of the disease.
Resourceful gardeners
Women gardeners found original indications for using Trichopolum in the garden. July is the month when in central Russia plants are susceptible to late blight. Tomatoes suffer the most from this disease. Productivity is reduced by half or more.
They offer an unusual use of the medicine - spraying it on tomatoes and cucumbers against late blight, when the use of other means is impossible due to the danger of toxic drugs. This treatment of plants, especially tomatoes, is cheaper, safer for health, and has good results. The question of how much to take the drug arises immediately.
It is recommended to dilute 20 tablets of 250 mg in 10 liters of water, treat the plants every 10 days, additionally after rain. Among the analogues of Trichopolum you can find those whose price is acceptable. The table below shows their prices.
Tradename | Manufacturer (country) | Price, rub.) |
Metrogil | India | 179 |
Klion | Hungary | 75 |
Flagyl | France | 125 |
Metronidazole | Norway | 71 |
Metronidazole | Russia | 15-24 |
The price indicated is for a pack of 20 tablets. The use of Trichopolum is possible for a variety of purposes. This drug has a bitter taste, a good effect when used correctly, and its price is affordable. We must not forget that the best result of its action in humans can only be obtained under the supervision of a doctor.
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Reviews
The medical drug "Trichopol" has a huge number of reviews on medical websites. This is due to the fact that it has been produced in our country for a long time and several generations of patients have been treated with it. And to this day, this drug remains practically indispensable in the development of many infectious pathologies.
Reviews from patients who were prescribed this pharmacological agent contain a lot of positive information about its effect on the body. Patients testify that the pathological processes in their body during treatment became less pronounced, their pain syndrome caused by inflammation of one or another organ quickly ceased, and the symptoms of intoxication disappeared. Women who used Trichopolum in the form of vaginal tablets also noted its effectiveness, the rapid elimination of unpleasant discharge and the normalization of their condition.
As for adverse reactions, this medication, according to patients, cannot boast of being well tolerated. In this case it is relative. Most people experienced signs of digestive disorders, severe nausea, abnormal bowel movements and an unpleasant taste in the mouth.
We reviewed the instructions for use and reviews of Trichopolum in tablets and suppositories.
When is it recommended to use
Metronidazole (Trichopol), like its analogs, has a wide spectrum of action on anaerobic microflora (those that live without oxygen). These are protozoa (giardia, trichomonas, amoebas), bacteria, the medicine can be used in the fight against Helicobacter pylori. The substance is quickly absorbed if used orally; within 8-10 hours it is partially destroyed by the liver and excreted in urine and feces. The instructions describe the indications for use of the drug in various fields of medicine:
- In gynecology, acute and chronic trichomoniasis is treated.
- Infectious disease specialists treat giardiasis, amebiasis, and cutaneous leishmaniasis.
- Therapists and surgeons use it for diseases of bones, joints, and internal organs associated with anaerobic infection (you can use one medicine or take an antibiotic at the same time, the compatibility of the drugs is taken into account).
- Dermatologists and cosmetologists use Trichopolum for acne (also analogues) in women and men as one of the means of treatment against demodicosis.
- Gastroenterologists believe that the medicine treats stomach and duodenal ulcers quite well if Trichopolum tablets 250-500 mg or analogues are part of the treatment complex.
- Oncologists are confident that the use of the drug increases the sensitivity of tumor tissue to radiation, which helps to better treat tumors using radiotherapy.
- Psychiatrists and narcologists know that the medicine slows down the utilization of ethanol and accumulates acetaldehyde in the blood, causing poisoning of the body. Trichopolum and alcohol become incompatible, which can be used as one of the methods of treating alcoholism.
The instructions describe contraindications for taking the medicine. Trichopolum should not be taken during pregnancy, breastfeeding, depressed state of hematopoiesis (blood tests are needed before treatment), and with certain diseases of the central nervous system. Indications for use of the drug are determined by the doctor. Side effects are possible from different systems and organs:
- Digestive – lack of appetite, nausea, vomiting, diarrhea.
- Central nervous – headache, staggering when walking due to dizziness, difficulty concentrating, inability to drive.
- Immune system – allergic rash, itching; frequent occurrence of fungal infection when applied topically.
- Hematopoietic system – the chemical composition of the drug inhibits the hematopoietic system. Side effects of this kind include anemia, a decrease in the content of leukocytes, and peripheral blood platelets.