Food and any other poisoning that causes intoxication of the body leads to large losses of fluid due to vomiting or diarrhea. And along with the fluid, the body also loses vital substances that are not easy to restore in a short time. To restore normal metabolic processes and water-electrolyte balance in case of poisoning, the drug Regidron is often prescribed. What it is, what substances are included in its composition, how to use it, how to dilute Regidron - all this will be discussed below.
Instructions for use
Compared to other similar drugs intended for preoral use, Regidron has a lower osmolarity value (260 mOsm/l, with a pH value of 8.2). Other differences from analogs are a higher sodium content, which helps prevent hypernatremia, as well as a higher potassium concentration.
pharmachologic effect
The action of Regidron is aimed at restoring the natural water-electrolyte and energy balance in the body. The drug eliminates the manifestations of acidosis and signs of dehydration. The medication is prescribed as part of the treatment of diarrhea, constipation, poisoning and desalination of the body. For children, Regidron can be used for rotavirus infection. The substances included in the drug compensate for electrolyte imbalance and correct metabolic acidosis.
Pharmacological properties:
- replenishment of fluid loss in the body due to vomiting and diarrhea;
- prevention of dehydration in infectious diseases;
- normalization of water and electrolyte balance during prolonged constipation.
Indications for use
Disturbances of water and electrolyte metabolism caused by:
- diarrhea with mild to moderate dehydration caused by poisoning, cholera and other factors;
- heat stroke (hyperthermia);
- high loads that cause increased sweating (the drug can be prescribed, including for preventive purposes).
Mode of application
The drug is taken orally without taking into account the time of meal and time of day. You can prepare a rehydration solution by dissolving Regidron powder in boiled water at a temperature of about 37 °C. The ratio of powder and liquid depends on whether the solution is taken for therapeutic or prophylactic purposes.
For treatment purposes, 1 sachet of Regidron weighing 18.9 grams is diluted in 1 liter of water. If the drug is taken to prevent dehydration, the amount of water is doubled.
The dosage of the drug depends on the severity of the disease and the patient’s weight.
- For diarrhea with mild dehydration (weight loss - no more than 5%), the drug is prescribed in a volume of 40-50 ml per kilogram of weight. In particular, an adult weighing 70 kg per day should drink 2.8-3.5 liters of solution.
- For the treatment of moderate diarrhea (weight decreases by 6-10%), the daily dose of Regidron is increased to 80-100 ml per kg of weight.
When treating severe dehydration, in which the patient has lost 10% of body weight or more, rehydration should be ensured through the use of intravenous medications. Only after this can Regidron be prescribed at a dose of 80-100 ml per kg of weight.
Taking the drug usually lasts 3-4 days or until diarrhea stops.
As part of maintenance therapy, after the cessation of symptoms of intestinal disorders, you can continue taking the solution in a volume of up to 100 ml per kg of weight for several days.
If correction of dehydration and taking other medications do not ensure cessation of diarrhea, the patient is prescribed an enhanced drinking regimen: depending on weight, an adult should drink from 8 to 10 or more liters of liquid, including Regidron solution, mineral water, etc. If diarrhea is accompanied by nausea and vomiting, it is advisable to pre-cool the liquid and drink in small doses. In the most difficult situations, fluid administration using a nasogastric tube is allowed, subject to medical supervision.
If, in addition to diarrhea, the patient experiences convulsions, Regidron solution is taken in fractional doses of 100-150 ml. It is important that every 40 min. the patient received 0.5 liters of solution, and it was necessary to continue taking it until the symptoms of the disorder disappeared.
Application for children
The drug should be taken as soon as the child has loose stools. Regidron powder is diluted in water according to the instructions. The drug should be taken in small sips each time after loose stools. Taking the drug must not be combined with the use of other medications, and the powder itself must not be diluted in a liquid other than water. It is forbidden to add sugar to the solution.
There is no need to interrupt nutrition or breastfeeding for the period of rehydration, but it is better to abstain from rich and heavy food during this period.
The dosage rate for the drug is from 30 to 60 ml for each kg of the child’s weight. It is necessary to continue using Regidron until diarrhea stops.
Release form, composition
The drug is available in the form of separate sachets with white powder for preparing an aqueous solution. The weight of one sachet is 18.9 g. Regidron contains:
- glucose or dextrose – 10 g;
- sodium chloride – 3.5 g;
- sodium citrate – 2.9 g;
- potassium chloride – 2.5 g.
Interaction with other drugs
Given the alkaline nature of the solution, Regidron should be taken with caution if you are using other medications, for the adsorption of which a certain intestinal pH level is important.
When prescribing other medications, it is important to consider that diarrhea can also affect the absorption capacity of the intestine.
What other conditions does Regidron help with?
The sorbing and rehydrating properties of the drug are used not only in the treatment of the consequences of poisoning.
- Regidron for vomiting caused by a violation of the intestinal microflora is also effective and indicated for use.
- The consequences of stomach upsets due to infectious diseases are also quickly eliminated by Regidron, taken in a standard dosage.
- For alcohol intoxication, accompanied by large losses of fluid, the use of Regidron is also indicated.
- For heatstroke with nausea, vomiting and dizziness, the use of Regidron is indicated.
- In case of profuse sweating caused by heavy physical exertion (for example, strenuous exercise in the gym), Regidron taken in time can prevent a sharp decrease in potassium in the blood (hypokalemia). Hypokalemia is manifested by weakness, cardiac dysfunction and even arrhythmia.
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Side effects
Taking Regidron in recommended doses and when indicated is rarely accompanied by adverse reactions. Allergic reactions to one of the components of the drug are potentially possible. Taking a large amount of solution very quickly may cause vomiting.
If Regidron solution is taken in excessive volume or increased concentration, hypernatremia may develop, which may be accompanied by weakness, drowsiness, neuromuscular excitation, a state of confusion, and in rare cases, coma or respiratory arrest.
When treating patients with impaired renal function, there is a risk of developing alkalosis, which is accompanied by deterioration of pulmonary ventilation, neuromuscular excitation, and convulsive syndrome.
Additional consultation with a doctor is necessary if the patient experiences the following disorders while taking Regidron:
- increased fatigue, drowsiness;
- slow speech, inability to answer questions;
- stopping urination;
- the appearance of bloody discharge in the stool;
- temperature above 39°C;
- duration of diarrhea for 5 or more days;
- sudden severe pain that accompanies the cessation of diarrhea.
Overdose
A single overdose of Regidron will not provoke serious disorders in the body. If dosages are regularly exceeded, the consequences may manifest themselves in the form of pathological conditions that require symptomatic treatment. The patient gradually develops weakness and confusion.
With a significant overdose, convulsive conditions, muscle and nervous excitability are possible. To identify other consequences, laboratory examination methods are used.
Other consequences of overdose:
- change in acid-base balance;
- critical lack of calcium;
- chronic fatigue syndrome;
- hypernatremia;
- blood in the stool (in combination with diarrhea);
- violation of blood composition indicators.
Contraindications
- Kidney disorders
- Diabetes mellitus (insulin dependent, non-insulin dependent)
- Intestinal obstruction
- Unconscious state
- Moderate and severe arterial hypertension
- Individual intolerance to Regidron components
Possibility of use during pregnancy
In recommended doses, Regidron can be prescribed to pregnant and lactating women . However, due to the high risk of hypernatremia and hyperkalemia, it is advisable to take the solution no longer than 4 days.
Contraindications
There are a number of diseases and conditions for which Regidron for nausea and vomiting is not used. These include:
- renal failure in the stage of decompensation;
- diabetes mellitus type 1 and 2;
- coma, loss of consciousness;
- intestinal obstruction due to spasm of the organ walls;
- the presence of individual intolerance to the active components, which can cause an allergic reaction.
It is undesirable to combine the solution with drugs whose effectiveness depends on the acidity of the internal environment.
special instructions
Impact on the ability to drive vehicles and operate machinery
Regidron does not have the ability to disrupt natural psychomotor reactions and does not affect the state of the central nervous system.
Pregnancy and lactation
Lactation and pregnancy are not absolute contraindications for the use of Regidron. The drug does not have a negative effect on the fetus, but during breastfeeding it is necessary to take precautions (during therapy it is recommended to prevent the drug from entering the body of the newborn baby).
Use in childhood
In pediatric practice, Regidron is used for poisoning, rotavirus infection and vomiting caused by heat stroke. The drug is approved for use in children over one year of age, but it must be taken under the supervision of a doctor and according to an individually designed regimen.
For impaired renal function
Severe renal pathologies are among the absolute contraindications for the use of Regidron. The medication can cause heart rhythm disturbances and general weakness of the body.
For liver dysfunction
The manufacturer recommends caution. Severe liver pathologies are grounds for additional consultation with a doctor.
Conditions for dispensing from pharmacies
Over-the-counter release.
Recommendations for taking medication for vomiting or diarrhea
In order for Regidron to work with maximum effect, the instructions for use for children with vomiting describe the main requirements for its use:
- The medicine is taken a quarter of an hour after the attack;
- glucose-saline solution is better accepted by the child’s body if given in small portions;
- if a child refuses to drink Regidron from a cup or spoon, you can give him the medicine using a syringe without a needle;
- the full dose of the solution is drunk over 15-20 minutes;
- if vomiting intensifies when drinking Regidron, you can drop a small amount of natural lemon juice into the prepared solution;
- The interval between doses of the drug after the condition improves increases and becomes from 1 to 3 hours.
During the periods between treatments, take deep breaths and exhales - this helps relieve spasms in the child’s body.
Important! If vomiting attacks are frequent, the amount of solution is slightly reduced to avoid stimulating nausea. But they give the child water more often - once every 10 minutes.
Instructions for using Regidron solution for diarrhea in children recommend starting to take the medication immediately after each case of dehydration in the near future. Use the drug until complete recovery, usually this period lasts up to 4 days. Before using the medicine, shake it so that the active components rise from the bottom of the container.
Varieties, analogues
There are three types of Regidron in pharmacies:
Optim is designed to help with the same symptoms; it differs in the weight of the sachet: 10.7 g. diluted in 0.5 liters of water - convenient for treating children. To improve taste, lemon flavoring, which causes allergies, is added. Allowed to be stored in the refrigerator, best consumed warm.
Bio helps against nausea, is not a drug, it is classified as a dietary supplement. It differs in the form of release. Consists of two sachets. The first contains beneficial bacteria to restore intestinal microflora, the second is regular Regidron with the addition of flavoring, sucralose, and silicon dioxide. The contents of both sachets are diluted in 200 ml of water.
There are many analogues in powder, ready-made form, and sterile bottles of various sizes. Ready-made solutions are taken intravenously, not orally.
- trisol - for intravenous administration;
- acesol - ready-made solution;
- trihydron - Russian analogue, powder;
- hydrovit - German analogue, powder.
Recommendations
Before starting treatment, read the instructions and correctly calculate the amount of medication based on the patient’s weight. When vomiting, it is better to drink the cooled solution in small sips. You cannot add sugar or other products that improve taste. Rehydron can be used as an effective remedy for diarrhea.
During the treatment period, exclude fatty, flour, and sweet foods. The suspension can be drunk regardless of meals. When it is not possible to buy Regidron at the pharmacy, you can make it at home: mix one tablespoon of sugar, salt, a quarter teaspoon of baking soda, half a liter of boiled water at room temperature. The electrolyte obtained in this way may be lower in quality than pharmaceutical grade, even if the proportions are observed.
You can desolder the patient at home for a maximum of 4 days. If relief does not occur, it is better to seek qualified medical help. Severe forms of dehydration are treated with intravenous medications under medical supervision.
The pharmacological drug Rehydron is widely used to correct the imbalance of electrolyte composition in the body during acute fluid loss (diarrhea, uncontrollable vomiting). Consider the specifics of using this drug in children.
How to prepare Regidron at home
The product can be bought at a pharmacy. But there are times when a person needs emergency help, but the treasured drug is not at hand. Then the usual ingredients that every housewife has in her kitchen will come to the rescue.
Required Ingredients
- table salt – 1 tsp,
- sugar – 2 tbsp. l.,
- baking soda – 1 tsp,
- drinking water – 1 liter.
Preparation of the solution
To prepare the solution, boil water and add the listed ingredients to it. Allow to cool to room temperature and the solution is ready for use.
Composition and release form of the drug Regidron
Rehydron is a powder of mineral salts and polysaccharides, packaged in sachets. Instructions for use are included with the drug packaging. Each sachet allows you to prepare 1 liter of solution at home. The finished liquid is a bitter-salty-sweet solution, similar in composition to human blood plasma. You can make the powder at home without much difficulty.
Recipe for making your own product:
It is impossible to replenish the loss of fluid in the body with plain water or other drinks (juices, sweet soda, milk, beer). They do not contain as many mineral salts as needed to restore the water-salt balance. Sodium performs an important function in regulating cardiac activity and maintaining osmotic pressure. Potassium – participates in the work of the “potassium-sodium pump” - the main mechanism for regulating intracellular pressure. Without it, normal functioning of the heart muscle, kidneys, and brain is impossible.
Overdose
Overdose (hyperkalemia) can occur if a more concentrated solution is prepared, or in case of a larger volume of use. This is expressed in the form of weakness, increased neuromuscular excitability, and drowsiness. A high degree of dehydration leads to confusion, coma and respiratory arrest.
In cases where the patient experiences the symptoms described below while taking Regidron, it is necessary to consult a doctor or call an ambulance.
- Increased temperature over 39ºС,
- Loose stools with blood, or not stopping for 2 days,
- Uncontrollable vomiting
- Severe pain in the abdominal area,
- Drowsiness, stupor, slow speech.