What effect can be obtained from treatment with Milgamma for osteochondrosis?

B vitamins are responsible for the processes of hematopoiesis, the functioning of the musculoskeletal system and the normal functioning of nerve fibers in the human body. In order to compensate for their deficiency, Milgamma is used: intramuscularly or orally (Milgamma is not administered intravenously). Intramuscular administration of Milgamma allows you to quickly eliminate painful sensations, since with this method of drug administration the necessary therapeutic concentrations are achieved within 10-15 minutes after the manipulation.

Despite the harmlessness of the drug, there are some recommendations on how to inject Milgamma correctly. Therefore, before starting use, you must contact a qualified specialist at the Yusupov Hospital, who will answer all questions, the most common of which are: “How many times a year can you inject Milgamma?”, “What time of day is it better to inject Milgamma - when is it better to inject Milgamma: in the morning or in the evening?”, “What syringe should I use to inject Milgamma?”, “How often can Milgamma be injected intramuscularly?” etc.

Rules of use

The manufacturer recommends using Undevit capsules after meals.
To prevent a lack of vitamins in the body, the product is used orally, one tablet daily. Under significant loads, during the recovery period after illness, surgery, it is recommended to use two to three servings per day. The manufacturer recommends a similar dosage for elderly people. Duration of treatment – ​​20-30 days. A pause is required between repeated courses; break - from a month to a quarter of a year.

"Undevit" is allowed from 14 years of age. As a prophylactic composition, a capsule is used daily, as an element of complex therapy - 2-3 doses daily.

An overabundance of the drug may manifest itself as nausea, vomiting and bowel dysfunction. Possible allergies, lethargy, irritability. An overdose of Undevit may cause headaches, stomach pain, and possibly impaired liver function. If such manifestations are observed, stop taking the drug and consult a doctor for a choice of symptomatic treatment.

Mode of application

In cases of severe pain, treatment begins with 1 injection (2 ml) per day. After the acute phase of the process or in case of mild pain syndrome, the drug is administered intramuscularly, 1 injection 2-3 times a week.

Under the supervision of a physician, a subsequent transition to treatment with the oral form of Milgamma® is possible. In this case, it is recommended to take one Milgamma® tablet 3 times a day.

The use of injections is more effective in the presence of systemic diseases, while tablets are recommended by doctors for maintenance therapy and for preventive purposes.

Contraindications, as well as side effects from use

Taking the drug can cause adverse reactions such as urticaria, itching, Quincke's edema, difficulty breathing along with dyspnea, increased sweating, acne and tachycardic signs. In addition, anaphylactic shock, bradycardia, convulsive contractions of the calf muscles, nausea and dizziness may occur. We know what vitamins are included in Milgamma.

Such side effects mainly develop in situations of accelerated intramuscular injection of the drug, as well as as a result of excessive dosages of the drug.

Among the existing contraindications for the use of Milgamma are the following:

• Adolescence up to sixteen years of age.
• The presence of myocardial conduction disorders.
• Danger of hypersensitivity or individual immunity to B vitamins.
• Heart failure in patients.
• One-time use with alcoholic beverages.

The composition of Milgamma vitamins in injections is the same as in tablets.

Method of use of the drug Milgamma, dosage

How to take Milgamma? For acute pain, a quick analgesic effect requires one injection of the drug Milgamma (2.0 ml), intramuscularly. For mild forms of the disease, the attending physician prescribes no more than 1 injection of Milgamma solution (2 ml) 2-3 times a week.

Milgamma tablets are intended for oral administration. Their composition is identical to the injection solution (B vitamins) and differs in the presence of excipients. Depending on the patient’s condition and his individual perception of certain components of the medicine, the doctor prescribes either tablets or injections of Milgamma.

The drug Milgamma has a wide analog range. These include medications such as Neuromultivit, Combilipen, Binavit. The international nonproprietary name of the active substance (INN) is the basic information about the drug. Drugs with the same active ingredients are produced under different trade names. The same can be said about the drug Milgamma. INN allows doctors to choose the right drug from a huge number of drugs available on the pharmaceutical market.

The use of milgamma for treatment and prevention

Milgamma is used in medical practice today as an active medicinal substance, and in some cases it is used for the prevention and prolongation of periods without exacerbation in the course of chronic diseases of the musculoskeletal system.

As a medicine, milgamma is used according to a certain scheme. Typically, at the beginning of the course, 1 intramuscular injection is given. The next day, the patient begins to take malgamma tablets. 1 tablet 3 times a day. In this case, depending on the severity of the disease and the severity of the pain syndrome, you can prescribe an additional 1-2 injections of milgamma per week. The course of treatment is 30 days.

Milgamma injections are not prescribed to prevent exacerbations and relieve vitamin deficiency conditions. Taking the pills starts at 3 a day. After a week, the dose is reduced to 2 milgamma tablets per day. During the third and fourth weeks, milgamma tablets are taken 1 per day.

Indications for prescribing milgamma may vary.

However, the main ones are associated with a lack of these substances in the patient’s body:

• deficiency of B vitamins;
• gout;
• rheumatism;
• osteochondrosis;
• spinal disc herniation;
• myopathies and neuropathy;
• alcoholic psychopathy;
• damage to nerve endings due to diabetes mellitus;
• paresis of innervation of the facial and jaw area;
• herpes and shingles.

It should be remembered that the drug milgamma is not the main drug for the treatment of these conditions. It only helps relieve unpleasant symptoms and create favorable conditions for the restoration of nerve endings. In addition to milgamma, for complex treatment it is necessary to prescribe adequate therapy, including various non-steroidal anti-inflammatory drugs and nootropic drugs. In the treatment of complications, therapy of the underlying disease plays an important role.

Milgamma dragee	1 tablet 3 times a day. The course of treatment is 1 month. From the second week the dose is reduced.
Milgamma in ampoules	2 ml once a week intramuscularly. The course of treatment is 4-5 injections of milgamma.

Where and how to inject Milgamma

The drug is not injected intravenously. It is injected deep intramuscularly using the thinnest and sharpest needle. Injections must be administered correctly to avoid damage to blood vessels and nerve bundles. It is recommended to inject into the gluteal muscle.

At the beginning of treatment (first 5-10 days), the dosage is 2 ml per day. Subsequently, in case of mild forms of the disease or improvement, Milgamma can be injected less frequently (twice or three times every 7 days for 2-3 weeks) or switch to oral intake of vitamins. The use of ampoules during treatment with Milgamma compositum tablets is allowed with the permission of the doctor

It is important that the doctor monitors the progress of therapy and the patient’s well-being. Recommended frequency of monitoring is once a week

If the patient is prescribed the drug Milgamma in injections, the instructions for use must be followed. You can read on the Internet that it is correct to inject the medicine into the leg, but the solution must be injected into the uppermost part of the buttock. This will help avoid the development of side effects and minimize discomfort.

Sometimes during therapy you have to take Movalis injections prescribed by your doctor. In this case, the drugs are injected into different buttocks. You can use medications at the same time, but mixing them in 1 syringe is prohibited.

When is the best time to give injections?

Many patients are interested in what time of day the injection solution in ampoules is used: in the morning or in the evening. The drug is a complex of vitamins, so it is better to use it in the first half of the day (at this time of day, metabolic processes are more intense).

If the medicine is used simultaneously with other medications for intramuscular administration, it should be used in accordance with the doctor’s recommendations.

What do you think are the most important factors when choosing a medical facility? Poll Options are limited because JavaScript is disabled in your browser.

Painful injections or not

It is difficult to answer the question whether Milgamma injections are painful or not. It all depends on the individual sensitivity of the patient and the injection technique. The drug contains lidocaine, the purpose of which is to minimize discomfort. However, this is not always possible, especially if the injections are given by an inexperienced person. If there is no one to give the injection, it is better to skip 1 day than to get into a nerve or vessel.

If the manipulations are painful, following these recommendations will help reduce discomfort:

1. The needle should be inserted deep into the muscle tissue.
2. It is necessary to slowly and smoothly press the syringe plunger so that the drug flows slowly. The optimal procedure time is 1.5 minutes.
3. After performing the injection, it is recommended to gently massage the muscle. This will ensure uniform distribution of the solution in the tissues and prevent the formation of a hematoma.
4. If a lump appears at the injection site, you can remove it using a warm compress or lotions based on magnesium sulfate.

How many days to inject Milgamma

Patients can be injected with Milgamma only after consulting a neurologist. The doctor will tell you how often to give injections and how long the course of treatment will last.

At the beginning of therapy, the drug is administered every day (number of ampoules - 1 pc.). Treatment according to this regimen continues for 5-10 days, after which the patient is transferred to oral administration of the medication. If necessary, intramuscular administration of vitamins continues. Patients are interested in how often the drug can be injected in this case. If the tablets can be taken 1-3 times a day, then the solution is administered no more than 2-3 times a week.

If the condition returns to normal, you need to periodically visit the doctor to decide on the need for repeated therapy. This should be done at least once a year.

Composition of the solution

The complex active ingredients in this medicine are B vitamins. The product includes pyridoxine (this is B6), which enhances metabolic processes in organs and tissues. This component improves the conduction of nerve impulses and affects the production of hemoglobin. Its combination with other representatives of group B affects the formation of serotonin, histamine and adrenaline. Thiamine (that is, vitamin B1) ensures the regulation of tissue energy resources and cells, the effect is reflected in the process of carbohydrate conversion.

Milgamma solution for injection is also significantly enriched with cyanocobalamin (B12), which affects the severity of pain, provides a moderate pain-suppressing effect and reduces the risk of developing anemia.

Injections achieve a local pronounced analgesic effect due to the presence of the analgesic lidocaine in the composition, which quickly relieves any discomfort. The use of this component helps restore motor function damaged due to neurological disease or pathologies of the musculoskeletal system.

Is it possible to inject Milgamma for oncology?

The opinion that Milgamma injections can be given for cancer is deeply incorrect. This drug can only worsen the patient's condition. This is explained by the fact that the main components of Milgamma are B vitamins, which can help accelerate the growth of malignant cells and significantly aggravate the problem.

In order to eliminate pain caused by the development of a malignant neoplasm, the use of completely different drugs is prescribed.

The benefit of Milgamma for cancer patients is minimal, while the harm caused by the drug in this situation can be quite significant.

Side effects

The likelihood of such reactions is extremely low, but increased individual sensitivity to the composition of the drug cannot be ruled out. Often, when side effects occur, patients experience skin reactions in the form of itching, rash, and urticaria. With the injection method of administering the drug, local manifestations are not excluded, which, as a rule, are caused by too high a rate of injection of the solution or failure to comply with standard aseptic requirements. The following types of effects may occur less frequently:

• The digestive system may respond with nausea or vomiting.
• There may be a feeling of dryness, flaking, mainly complaints about the skin of the face and lips.
• Presence of depressed breathing.
• Increased drowsiness along with episodes of confusion.
• Disturbances in the rhythm of the heartbeat.
• The occurrence of convulsive syndrome and increased sweating.
• Anaphylactic shock cannot be ruled out.

Any side effects when using this drug are a reason to consult a doctor. Normally, the medication in question does not have a negative effect on the speed of reactions and mental function, which allows it to be used when driving a car and work that requires special attention.

Indications and contraindications

The annotation for the drug contains the following list of diseases for which the medicine should be used:

• radicular syndrome;
• osteochondrosis;
• myalgia;
• neuritis;
• neuralgia;
• polyneuropathy;
• impaired motor function caused by crippling pain;
• muscle paresis;
• convulsive syndrome.

Milgamma is used only as part of complex therapy. As a single agent in the treatment of inflammatory and degenerative diseases of the spine and nerves, it is ineffective.

But it is worth noting that for pain in the lower back and other parts of the spinal column, the effectiveness of Milgamma is equal to Diclofenac. After using the drug, pain subsides and functional activity is restored. That is why Milgamma tablets and injections should be used to treat back pain caused by diseases of the nervous or musculoskeletal system.

This is a good remedy for osteochondrosis. The disease is characterized by degenerative-dystrophic changes in the spine, intervertebral discs are affected, and the spinal column cannot fully perform its functions. As a result of the processes occurring, severe pain appears. This is a consequence of pinched nerve endings. Milgamma not only relieves pain, but also improves the condition of the nervous system.

Not everyone can be treated with Milgamma. The drug is not suitable for children.

Contraindications to the use of Milgamma:

• individual intolerance to components;
• severe stage of acute or chronic heart failure;
• pregnancy and lactation.

The drug should be prescribed by a doctor. If treatment is necessary for children under 16 years of age, then a safer remedy is selected, since Milgamma contains an excessive amount of vitamins for a given age.

Using the medicine for children under 16 years of age contrary to the prohibitions will lead to hypervitaminosis, which can cause disturbances in the functioning of the nervous system.

Composition of vitamins and their effect on the human nervous system

The composition of Milgamma vitamins, as noted above, consists of a complex of B vitamins.

The following composition is typical for injections in the form of injections:

• Thiamine “B1” is designed to ensure normal carbohydrate metabolism, which contributes to the healthy state of nerve tissue. If the human body is deficient in this element, this can provoke an accumulation of carbohydrate metabolites, which will lead to the development of a large number of pathological conditions.
• Pyridoxine “B6”, as part of its metabolism, takes part in the production of adrenaline, histamine, dopamine, serotonin and amino acid metabolism. In addition, “B6” serves as an active and indispensable participant in the processes associated with the formation of hemoglobin. What else is included in Milgamma vitamins?
• Cyanocobalamin “B12” is associated with antianemic functions; in addition, it is indispensable in the processes of synthesis of choline, methionine, creatinine and nucleic acids. The substance cyanocobalamin is considered an active participant in metabolic processes that has an analgesic effect.

Excipients in the production of injections are sodium hydroxide and polyphosphate, water, lidocaine hydrochloride along with potassium hexacyanoferrate.

Milgamma vitamin tablets contain the following components:

• Pyridoxine, which is indispensable in protein metabolism, taking part in the process of fat and carbohydrate metabolism.
• Benfotiamine, considered one of the forms of thiamine “B1”, is actively involved in carbohydrate metabolism.

Excipients in this case are colloidal silicon dioxide, as well as talc and povidone.

The composition of Milgamma vitamins is universal.

Vitamins Milgamma: reviews from patients and doctors

By analyzing the totality of the complex of vitamins that make up Milgamma, you can understand the benefits this drug brings to the human body. It is the B vitamins that have a positive effect on the overall strengthening of the immune system and have a powerful therapeutic effect in the treatment of diseases of the central nervous system and musculoskeletal system. Thanks to the use of Milgamma, specialists achieve quick relief from acute pain; the treatment brings a long-term positive effect. In addition, experts recommend taking Milgamma vitamins for various diseases of internal organs, since this replenishes the elements and nutrients that a weakened body lacks.

Medicine Milgamma special instructions

Milgamma can be purchased in pharmacies in ampoules, only with a prescription from a specialist. The tablets can be purchased without providing a prescription from a doctor.

Storage conditions

The drug contains a special vitamin complex, so it can be stored at a temperature of 15 degrees. The drug should not be exposed to direct sunlight; in addition, it should be stored in a closed place where children cannot enter.

Best before date

The medicine Milgamma is stored for no more than two years

Before purchasing the drug, you must pay attention to the storage conditions, as well as the date of manufacture.

special instructions

If the patient needs to administer the drug intramuscularly, a medical professional must be present, since in this case adverse reactions may occur faster. It is necessary to ensure the correct administration and dosage of the medicine. The medicine Milgamma can be used while driving, as it does not affect mental capacity

Milgamma should be prescribed with caution in combination with drugs that contain cycloserine. In addition, vitamin B12 is not compatible with heavy metal salts

Reviews

Experts speak positively about the product “Milgamma compositum”. Analogues also have good reviews. The described products can be purchased in the form of tablets and solution for injection. After completing the course, the body’s immunity increases, inflammation and pain in the spine go away, the causes of stress are eliminated and sleep is normalized. At the beginning of treatment, you can inject the medicine for seven days, and then switch to the tablet form.

Experts note that the B complex of vitamins has a good effect on hair growth, skin and nails. It is recommended to undergo a course of therapy once a year if there is a deficiency in the body. The medicine is especially useful for degenerative changes in the cervical, lumbar and thoracic spine.

Only after studying the instructions and consulting a doctor should you use the drug “Milgamma compositum”. Self-medication is not advisable. Negative reviews make it possible to understand that ignoring the doctor’s recommendations can lead to the development of side effects.

Other analogues:

• "Neuromultivit";
• "Binavit";
• "Neurobion";
• "Neurorubin";
• "Neurobeks".

Side effects and overdose of milgamma tablets

• Skin reactions;
• Hives;
• Exanthema;
• Anaphylactic shock.

If unexpressed hypersensitivity reactions develop, doctors discontinue the drug and prescribe enterosorbents and antihistamines. If the patient develops anaphylactic shock, blood substitutes, antihistamines, and glucocorticoids are administered intravenously.

• Dizziness;
• Confusion;
• Sensory neuropathy (with duration of milgamma therapy for more than 6 months).

Rarely, patients are bothered by nausea. Taking milgamma tablets orally is not accompanied by overdose symptoms. High doses of vitamin pyridoxine (more than 1000 mg per day) can cause neurotoxic effects. Overdose is manifested by sensory neuropathy, sometimes ataxia (impaired coordination of movements). Extremely high doses of vitamin B6 can lead to seizures.

When taking pyridoxine hydrochloride at a dose above 150 mg per 1 kg of body weight, patients are given gastric lavage and enterosorbents. Vomiting is most effective in the first 30 minutes after taking milgamma tablets. Intensive therapy is carried out according to indications.

Indications, contraindications, method of use milgamma

Doctors at the Yusupov Hospital prescribe milgamma tablets to patients who have neurological disorders of various origins caused by a deficiency of vitamins B1 and B6. Contraindication is increased individual sensitivity to the active and auxiliary ingredients of the drug. Due to the lack of data on the effect of the drug on the children's body, milgamma tablets are not prescribed to children under 18 years of age. The decision to use the drug for pregnant and breastfeeding women is made individually by neurologists at the Yusupov Hospital. Milgamma tablets are used if the intended benefit outweighs the potential risk to the fetus and newborn baby.

Adult patients are prescribed one milgamma tablet per day. If indicated, the dose is increased to three tablets. After 4 weeks from the start of milgamma therapy, doctors collectively decide on the advisability of further taking the drug, 1 tablet 3 times a day. To reduce the risk of developing neuropathy caused by vitamin B6, which is included in milgamma tablets, treatment is continued at a dose of 1 tablet per day. There is no dose adjustment for patients with impaired liver function, kidney function, or elderly patients.

Patients are interested in how to take milgamma tablets - before or after meals. The official instructions for the use of milgamma tablets contain information that the drug is best taken after meals. The drug should be taken with a sufficient amount of clean still water.

Pharmacokinetics and pharmacodynamics

Thiamine. From the information given in the annotation, it follows that after intramuscular administration, thiamine is quite quickly adsorbed and enters the blood, however, it is distributed unevenly in the body. This substance is able to penetrate the placental and blood-brain barriers. It is excreted through the kidneys. Also, thiamine does not tend to accumulate in the body, so it must be taken daily. Pyridoxine. After injection into the muscle, it also enters the bloodstream in a short time and spreads throughout the body.

It is important that about 2/3 of this substance is able to combine with plasma proteins. It easily penetrates the placental barrier and enters the milk of a nursing woman

Later, the process of oxidation to 4-pyridoxic acid occurs, which is excreted through the kidneys within 2-5 hours. Cyanocobalamin. When it enters the human body, it binds with proteins, resulting in the formation of the so-called transport complex. Next comes absorption into the liver tissue. The accumulation of the substance occurs in the bone marrow. After the substance enters the intestines with bile, there it again acquires the ability to be absorbed.

Release form

Milgamma is available in the form of tablets and a solution intended for deep injection into the muscle. In pharmacies, the product can also be seen under the trade name “Milgamma Compositum”. These are different drugs, since Milgamma Compositum tablets contain only two components: vitamin B1 (in the form of benfotiamine) and pyridoxine. The dragee does not contain lidocaine and other anesthetics, so it cannot be prescribed for the relief of acute pain syndromes, for example, lumbodynia.

Milgamma solution for intramuscular injection has a red color and a pronounced odor. 1 ampoule contains 2 ml of solution.

Milgamma tablets have been discontinued from sale and production in some regions, so this name and dosage form refers to Milgamma Compositum tablets.

Patients should take into account that the instructions for use of Milgamma Compositum differ from the instructions for use of Milgamma tablets, therefore this drug should not be used as replacement therapy without consulting a doctor.

What is it used for?

• neuralgia;
• neuritis;
• alcoholic and diabetic polyneuropathy;
• ganglionitis;
• diseases of the facial nerve;
• radiculopathy and other diseases caused by spinal osteochondrosis;
• congenital and acquired brain pathologies;
• multiple sclerosis;
• vitamin deficiency.

In case of deficiency of B vitamins, Milgamma is prescribed as a general tonic to prevent the possible development of neuralgic diseases. In all other cases, the drug is used to normalize the functioning of the central nervous system and eliminate existing nervous disorders.

Why is Milgamma injected?

The described drug is used to treat a large number of syndromes and diseases of the musculoskeletal system and nervous system:

• plexopathies;
• neuralgia;
• facial nerve paresis;
• ganglionitis;
• neuritis;
• herpes zoster;
• neuropathies;
• retrobulbar neuritis;
• diabetic polyneuropathy;
• night convulsive muscle contractions;
• radiculopathy;
• muscular-tonic syndrome;
• alcoholic polyneuropathy;
• lumboischialgia;
• myalgia;
• herpes virus infections that affect joints;
• polyneuropathy.

It is necessary to understand that Milgamma can only be used while taking other, more potent drugs; this must be taken into account before injecting Milgamma intramuscularly. The use of this vitamin solution helps improve blood microcirculation, activate hematopoietic processes, stabilize the functions and conductive abilities of the nervous system.

In addition, Milgamma is an excellent general strengthening agent, which is prescribed to individuals with a lack of B vitamins.

The drug Milgamma Compositum

The drug is intended for the treatment of pathologies of nervous tissue, diseases caused by degenerative changes in nerve endings and loss of nerve conduction. It is used in orthopedics to alleviate the condition of diseases of the musculoskeletal system. May promote the synthesis of serotonin, which has an analgesic effect. Main active ingredients:

• Benfotiamine (a derivative of the fat-soluble substance thiamine (vitamin B1);
• Pyridoxine hydrochloride (vitamin B6).

Thiamine normalizes carbohydrate metabolism, which leads to an improvement in the condition of nervous tissue. Transforms into diamine diphosphate and triphosphate. Without vitamin B1, the body accumulates too many carbohydrate metabolites. B6 is processed into pyridoxal phosphate, an enzyme that is responsible for the non-oxidative metabolism of amino acids and is involved in the production of proteins. Absorbed by the upper parts of the duodenum during passive diffusion. Excretion occurs through urine, the fractional half-life of B1 from the blood is 3-6 hours, B6 – 2-5 hours.

Compound

One tablet of medicine contains:

Active ingredients	Excipients	Shell composition
Name	mg	Name	mg	Name	mg
benfotiamine	100	Microcrystalline cellulose	222	shellac	3
Pyridoxine hydrochloride	100	povidone	8	sucrose	92
Omega-3 triglycerides (20%)	5	Calcium carbonate	92
Silicon dioxide colloidal	7	talc	55
Carmellose sodium	3	Acacia gum	14
talc	5	Corn starch	10
Povidone	8
Macrogol-6000	2
Glycerides of higher acids.	2,8
Molisorbate-80	0,17
Mountain glycol wax	0,12

Release form

The release form of the drug is round, biconvex tablets, coated with a white coating. Packaging – cell contour blister of 15 tablets. Available in two versions - 30 and 60 tablets per package. It belongs to the pharmacological group “Vitamins” and is sold in pharmacies without a prescription, but the first dose is prescribed by a doctor.

Indications for use

The drug can be prescribed as a general tonic for the prevention of diseases of the central nervous system. The medicine is prescribed for the following diseases:

• neuritis, neuralgia;
• neuropathy;
• facial nerve cut;
• plexopathy;
• retrobulbar neuritis;
• alcoholic or diabetic neuropathy;
• radiculopathy;
• muscular-tonic syndromes
• ganglionitis;
• nocturnal muscle cramps;
• muscular-tonic syndromes.

Composition and effects

The drug has a combined composition, therefore it has a complex effect:

• reduces pain;
• improves blood circulation;
• normalizes the functioning of the nervous system, is responsible for the transmission of nerve impulses;
• has a neuroprotective effect;
• participates in the process of hematopoiesis.

Thanks to this effect, the medicine can be used for neurological diseases that lead to back pain.

The composition of Milgamma is represented by three active components:

• thiamine (B1) – is responsible for carbohydrate and protein metabolism, regulates the passage of nerve impulses, and provides an analgesic effect;
• pyridoxine (B6) – takes part in the decarboxylation of amino acids and the synthesis of neurotransmitters;
• cyanocobalamin (B12) – normalizes the activity of the nervous system, improves blood circulation and transmission of nerve impulses.

It also contains auxiliary components, the list of which depends on the form of release.

The advantage of this drug is its high bioavailability. For Milgamma in ampoules it is 100%. High bioavailability is based on the fact that vitamin B1, when administered by injection, immediately enters the cells, remaining there for a longer time. When taken orally, passing through the gastrointestinal tract, most of the thiamine is destroyed.

Indications for use

The drug Milgamma is prescribed to patients experiencing a deficiency of B vitamins, which leads to neurological diseases:

• neuritis;
• neuralgia;
• polyneuropathy - diabetic, alcoholic, etc.;
• myalgia;
• radicular syndromes;
• retrobulbar neuritis;
• herpes zoster;
• facial nerve paresis.

In addition, the drug is recommended as an auxiliary in the treatment of a number of diseases: arthrosis, inflammation of the pancreas, gout, adenomyosis, Epstein Barr virus (viral infection, type herpesvirus). For pain in the hip joints, it is often used in combination with the drug Milgamma titanol. Instructions, price, recommendations on the use of these drugs - all this can be found out in detail during a consultation with your doctor.

In addition to providing a powerful therapeutic effect in the treatment of diseases of internal organs, the nervous system and the musculoskeletal system, the drug Milgamma is also successfully used to solve cosmetic problems. The Milgamma vitamin complex is indispensable for hair and skin; it helps saturate the human body with the missing elements, without which the beauty and strength of hair would be at risk. After all, the most common cause of hair loss is insufficient saturation of the hair follicle with vitamins. The advantages of the Milgamma vitamin complex for hair include:

• hair strengthening;
• reduction of hair follicle loss;
• saturation of hair with oxygen and nutrients;
• participation in the process of formation of new bulbs;
• normalization of the activity of the sebaceous glands.

Milgamma drug, manufacturer, country of origin

The drug Milgamma, the patent belongs to the Representative Office of VERWAG PHARMA GmbH&CoKG in Ukraine.

Manufacturer: Mauermann-Artsnaimitel KG, Germany. Heinrich-Knothe-Strasse 2, 82343 Peking, Germany.

Painful sensations experienced during human life, disorders of the nervous system should not be ignored, because in this way our body gives alarm signals. And this is a serious reason to turn to experienced specialists for advice and prescribe a course of treatment. Uncontrolled medication use and self-medication can lead to sad and unpredictable consequences.

At the Yusupov Clinic, the prevention and treatment of diseases of the nervous system and musculoskeletal system are successfully carried out under the supervision of leading doctors in the capital, thanks to high-tech equipment and widely used modern methods of medicine. More detailed information can be obtained from hospital consultants by making an appointment.

Author

Milgamma injections and their side effects

Milgamma is prescribed to patients for various neuralgic diseases.
In any form, the drug can be used if a person is constantly tormented by neuralgia and neuritis. In addition, Milgamma injections have long been helpful in curing nerve paresis of the facial area. Doctors often prescribe the medicine, since it contains a high concentration of B vitamins, which help with polyneuropathy, and the drug also actively fights alcoholic and diabetic polyneuropathy. Tablets are often prescribed if a person suffers from myalgia, neuralgia, or herpes zoster.

In medicine, Milgamma is also known as an effective remedy that helps cope with many pathologies of the nervous system, which most often arise due to a deficiency of vitamins B1 and B6. Injections are effective for diseases when the tablet form of the drug is powerless. The patient may be bothered by diseases such as neuropathy, plexopathy.

In addition, the drug in ampoule form is prescribed for ganglionitis, when a person is bothered by muscle cramps at night (in this case, the drug Petnidan Saft can also be prescribed). The drug is effective for osteochondrosis, radiculitis; often Milgamma is the only salvation for the patient when he has muscular-tonic syndrome.

Contraindications

Milgamma should not be prescribed to patients who suffer from heart failure during pregnancy and breastfeeding. The drug is contraindicated in cases where there is an intolerance to B vitamins or any other component included in the Milgamma drug. Injections are not prescribed to children until the child reaches the age of 14 years.

Side effects

Often the drug is tolerated quite well by patients, but in some cases you need to be prepared for the fact that Milgama will cause some side effects that can affect the functioning of absolutely any organ.

Milgamma can cause allergies, if it is not noticed in time, a person may experience anaphylactic shock or Quincke's edema. The drug in some cases leads to a malfunction of the nervous system, which is manifested by dizziness. The patient's cardiac activity may be affected by the drug, namely tachycardia or arrhythmia. In rare cases, Milgamma leads to nausea, vomiting, and convulsions.

pharmachologic effect

The presence of neurotropic vitamins included in group B in the Milgamma formula allows them to be used to treat problems with:

• nerve tissues;
• musculoskeletal system (MS);
• nerves;
• joints (for degenerative-dystrophic diseases).

The use of Milgamma as an injection solution helps reduce acute pain, activate microcirculatory processes, improve the functioning of the nervous system (NS) and blood formation.

Let's consider the effect of the main components of the drug on the body.

1. Thiamine (B1). Through phosphorylation it is transformed into thiamine triphosphate and cocarboxylase. During subsequent carbohydrate metabolism, cocarboxylase helps normalize nerve tissue and improve nerve conduction. A lack of vitamin B1 contributes to the accumulation of under-oxidized products of carbohydrate metabolism and provokes the development of various pathologies.
2. Pyridoxine hydrochloride (B6). As a result of phosphorylation and metabolism, the body begins intensive production of physiologically active mediators:

• adrenaline;
• serotonin;
• histamine;
• Gryptophan;
• dopamine;
• tyramine.

It is the action of vitamins B1 and B6, both individually and in interaction with each other, that leads to a beneficial effect on the well-being of people with NS and OPS diseases.

1. Lidocaine. Acts as a local anesthetic.
2. Cyanocobalamin (B12). Promotes an antianemic effect, activation of synthesis in nucleic acids, methionine, creatinine, choline, activation of nucleic acid metabolism and reduction of pain associated with damage to the peripheral nervous system.

Instructions for the use of tablets and injections

The greatest therapeutic effect is achieved through intramuscular injections of Milgamma. The recommended dosage of the drug is 2 ml intramuscularly, and the drug should be administered deeply once a day. If the goal is maintenance treatment, then a dosage of 2 ml of the drug is administered intramuscularly once every two days.

Milgamma tablets

The tablet form of the drug is usually used as an adjuvant therapy, the recommended dosage is 1 tablet once a day.

The course of vitamin therapy with Milgamma lasts 10-30 days.

Since the drug does not affect psychomotor reactions, there are no contraindications to its use when driving vehicles or working with moving mechanisms.

Overdose

When overdosing with Milgamma, patients experience adverse reactions, only in an even more pronounced form. In such a situation, symptomatic treatment is indicated.

During pregnancy

Due to the fact that no studies have been conducted to study the effect on the fetus, it is not recommended to take Milgamma during the lactation period and during pregnancy.

Interaction

When Milgamma is taken simultaneously with certain substances, vitamin B1 completely disintegrates in the body, without providing proper treatment, then other vitamins stop working, so no therapeutic effect can be expected in this case.
The lack of effect of vitamin therapy occurs when vitamin B1 interacts with the following substances:

• Magnesium sulfate (Magnesia) is a drug with a laxative, choleretic, sedative, antispasmodic, vasodilator, anticonvulsant, hypotensive and antiarrhythmic effect;
• Mercury chloride (Mercuric chloride) is an antiseptic and disinfectant;
• Potassium iodide - used in the treatment of thyroid hyperactivity, endemic goiter, hyperthyroidism, syphilis, pathologies of the respiratory tract and eyes;
• Riboflavin (vitamin B2);
• Glucose;
• Ferrous ammonium citrate – food additive E381, antioxidant and antioxidant;
• Acetates are esters and salts of acetic acid;
• Tannic acid is a fairly common component in many medicines;
• Lithium carbonate is a strong antipsychotic and sedative used for schizophrenia, chronic alcohol dependence, manic disorders, etc.

In addition, the activity of vitamin B1 decreases with an increase in the acid-base balance in the body, as well as when interacting with drugs containing copper.

If we talk about vitamin B6, its effect reduces the effectiveness of antiparkinsonian drugs (for example, Levodopa). Therefore, you cannot take such drugs at the same time. Some heavy metal salts deprive vitamin B12 of its beneficial properties.

Features of application

Milgamma injections can also be given as maintenance therapy, complex treatment, or as an independent remedy for pain relief. Injections are performed only intramuscularly. An injection is made deep into the muscle, the medicine is administered slowly, since with rapid administration the patient may experience palpitations, dizziness and even fainting. To relieve pain, you need to inject Milgamma 2 ml once a day for 3-4 days. The doctor monitors the patient’s standing and, if necessary, extends the course of treatment to 10 days.

If Milgamma is prescribed as maintenance therapy, then it should be injected 2-3 times a week. The course of treatment is one month. According to indications, the doctor may extend the duration of the procedures for another week. It should be remembered that Milgamma should not be injected often, since it contains a high concentration of vitamin B complex. An excess of vitamins, as well as their deficiency, has a bad effect on the condition of the body. Therefore, if an extension of treatment with a vitamin complex is required, the doctor prescribes analogues that have a similar effect, but are less concentrated.

The most commonly used analogues of Milgamma are:

• Nevriplex;
• Neurobics;
• Vitaxon;
• Combilipen;
• Binavit;
• Vitagamma;
• Trigamma.

Analogs are available in the form of an injection solution and tablets. The doctor decides which form of substitute to prescribe, based on the symptoms, the patient’s condition, and the nature of the disease. If there is pain, in order to relieve it, the doctor prescribes an intramuscular injection of an analogue of Milgamma. Treatment is carried out under the supervision of a doctor. You cannot prescribe Milgamma yourself, since an overdose of vitamins can lead to allergic reactions and even anaphylactic shock.

Contraindications and side effects

Contraindications to the use of the drug are:

• intolerance by the body to B vitamins or any other component included in the composition;
• heart failure;
• age up to 16 years.

It is also not recommended to prescribe the drug to pregnant and lactating women. This can only be done in extreme cases as prescribed and under the constant guidance of the attending physician.

Side effects most often occur as a result of neglecting contraindications, as well as in case of overdose. They can be expressed in such manifestations as:

• nausea and vomiting;
• allergic reactions;
• itching and urticaria;
• increased sweating;
• irritation at the injection site (with intramuscular injection);
• tachycardia.

Usually, a side effect after using the drug goes away on its own; if this does not happen within a few days, you should consult a doctor who has prescribed treatment to replace the drug.

Contraindications to the use of Milgamma

The main contraindications to the use of Milgamma are:

• heart failure in the stage of decompensation;
• disruption of cardiac muscle conduction;
• individual intolerance to one or another component of the drug.

Both the tablet and injection forms of Milgamma are contraindicated for children under 16 years of age, which is associated with an increased content of vitamins compared to age standards. The use of this vitamin complex in childhood threatens the development of hypervitaminosis and deviations in the development and functioning of systems and organs.

The gestational period and lactation are not contraindications to the use of Milgamma, however, due to the lack of research, the use of the drug during these periods is not recommended.

To avoid overdose, Milgamma is prescribed with caution while taking other medications and vitamin complexes containing pyridoxine, thiamine, and cyanocobalamin.

How to store Milgamma in ampoules

How to store the drug depends on the release form of Milgamma: the storage conditions for ampoules are somewhat different from the storage conditions for the tablet form.

Milgamma tablets should be stored in a dry, cool place, at a temperature not exceeding 25 degrees Celsius.

Milgamma ampoules must be stored at a temperature not exceeding 15 degrees Celsius, in a dark place, protected from sunlight.

Despite the fact that Milgamma is an over-the-counter drug, it is highly not recommended to purchase and use it independently, without the recommendation of your doctor. Like any medicine, it has a number of side effects and may not only be ineffective in one case or another, but also cause harm to the body.

You can undergo a thorough medical examination to identify indications and contraindications for the use of Milgamma at the leading medical center in Moscow - Yusupov Hospital. Diagnostic studies are carried out using the latest equipment from leading medical equipment manufacturers, which ensures maximum accuracy of results.

Doctors at the Yusupov Hospital are highly qualified specialists who will individually select for each patient the required dosage of the drug and the most appropriate method of administration: oral or injection.

You can make an appointment for a consultation with a specialist at the Yusupov Hospital and ask all your questions by phone or online on the clinic’s website.

Author

Alexey Vladimirovich Vasiliev

Head of the Research Center for Motor Neuron Disease/ALS, Candidate of Medical Sciences, doctor of the highest category

Milgamma injections: how many days to inject Milgamma

Before starting therapy with this drug, it is necessary to consult with a neurologist, who will decide how often Milgamma injections can be given, when to inject - in the morning or evening, and select the required dosage. To receive qualified advice, you can contact one of the leading centers in Moscow - the Yusupov Hospital.

The duration of the therapeutic course of Milgamma for persons with severe pain syndrome can be from five to ten days. Injections are given daily, the daily dosage is 2 ml. After the acute inflammatory process subsides and the intensity of pain decreases, Milgamma Compositum is prescribed orally. However, in some cases, the doctor may recommend continuing intramuscular administration of the drug, but not more than two to three times a week.

Our specialists

Andrey Igorevich Volkov

Neurologist, Candidate of Medical Sciences

Daria Dmitrievna Eliseeva

neurologist, candidate of medical sciences

Tatyana Aleksandrovna Kosova

Head of the Department of Rehabilitation Medicine, Physiotherapy Physician, Neurologist, Reflexologist

Elena Gennadievna Petrova

Physiotherapist, Candidate of Medical Sciences

Maxim Vladimirovich Chulkov

Instructor-methodologist in physical therapy, kinesiotherapist

Sergey Olegovich Molchanov

Instructor-methodologist for physical therapy

Alcohol compatibility

Are Milgamma and alcohol compatible? Can they be taken at the same time? If the patient drinks alcohol during therapy, the treatment will be of no use. He will waste his money; in addition, there is a high probability of complications and adverse reactions.

Before you start taking the medicine, you should give up alcoholic beverages a few days before so that the breakdown products of ethanol are removed from the body. To speed up this process, you can take sorbents.

What should you expect if you take Milgamma and do not give up alcohol? The consequences are:

• headache, dizziness;
• dysfunction of the liver, cardiovascular system;
• drowsiness, depression;
• disorientation in space;
• loss of consciousness.

The load on the heart, blood vessels and liver increases, and the likelihood of complications from these systems is high.

Prices for services *

Name of service	Price
Consultation with a rehabilitation specialist (initial)	Price 5,150 rub.
Consultation with a rehabilitation specialist (secondary)	Price 3,600 rub.
Comprehensive rehabilitation program after stroke	Price from 14,839 rub. per day
Comprehensive rehabilitation program after spinal injury	Price from 15,939 rub. per day
Comprehensive rehabilitation program for Alzheimer's disease	Price from 15,389 rub. per day
Comprehensive rehabilitation program for Parkinson's disease	Price from 13,739 rub. per day
Comprehensive rehabilitation program for multiple sclerosis	Price from 14,839 rub. per day
Massotherapy	Price from 2,200 rub.
Session with a speech therapist	Price from 3,410 rub.
Individual lesson on psychological social adaptation	Price 4,565 rub.
Acupuncture session	Price 4,290 rub.

We work around the clock

Sign up for a consultation by phone or send a request through the form

Dosage

The medicine is prescribed orally. For adults, one tablet once a day is enough. The product should be taken without chewing and with plenty of water. In rare cases, on the recommendation of a doctor, the medicine is prescribed three times a day. The daily norm can be adjusted depending on the severity of the disease, as well as the individual characteristics of the body.

The risk of overdose is low. Only in rare cases can neurotoxic effects be observed. With a long course and increased dosage, the development of neuropathy is possible. Also, taking the drug in high doses can provoke seizures. If there are symptoms of poisoning, the patient needs to rinse the stomach, give a sorbent to drink and begin detoxification therapy.

Storage conditions

When storing the drug Milgamma, the manufacturer's instructions note the fact that the drug must be kept in a cool, dark place: in cabinets, a first aid kit, etc. Exposure to direct sunlight is dangerous because the active components of Milgamma deteriorate much faster under their influence.

The most acceptable storage temperature for the drug is individual for each release form: for tablets - no higher than 25 degrees, for solution - no higher than 15.

Compositions of dosage forms and features of pharmacological action

The drug is available on the market in two forms: dragee tablets and solution for injection. The injection form is considered more preferable due to its rapid penetration into the bloodstream and increased efficiency of absorption and exposure while eliminating the processing factors of drug components in the digestive tract.

Milgamma Compositum in the form of tablets for oral administration and solution for injection have differences in the composition of the drug.

Average cost of a medicine in pharmacies:

• tablets No. 30 – 700 rubles;
• dragee No. 60 – 1200 rubles;
• injection solution, 5 ampoules of 2 ml – 300 rubles;
• injection solution, 25 ampoules of 2 ml – 1200 rub.

Pharmacies sell ampoules, dragees, and cream.

The remedy is a combination of three components: B1, B6, B12.

Thiamine (B 1) is a salt that is soluble in water. Its concentration in body tissues reaches 50% when taken orally.

https://www.youtube.com/watch?v=ytpress

He takes part:

• In providing pain sensitivity to the nerve, renewing damaged nerve fibers, promoting the signal along the sensitive endings;
• Protecting the cell membrane from the destructive effects of substances formed during oxidation;
• In the mechanisms of energy synthesis in the cell.

Benfotiamine is a fat-soluble salt of thiamine. It is absorbed almost 100% in the gastrointestinal tract, therefore it has advantages when taken orally compared to the usual water-soluble form.

Pyridoxine (Vit B 6):

• Improves metabolic processes in the nervous system;
• Antioxidant;
• Normalizes protein metabolism, prevents the accumulation of ammonia, a poison dangerous to nerve endings;
• Regulates amino acid metabolism.

Vitamin B 12 (cyanocobalomin):

• Used in the construction around the nerve ending of the myelin sheath;
• Regulates the processes of transformation of lipids, carbohydrates and proteins.

Milgamma tablets composition of vitamins:

• Benfiothiamine 100 mg;
• Pyridoxine (B6) 100 mg.

General characteristics of the drug

This medicine belongs to vitamin preparations. But the concentration of active ingredients in it is such that it can only be used as prescribed by a doctor. Self-medication can lead to an overdose of B vitamins, which is unsafe for health. Only a doctor can determine how much Milgamma can be injected and in what dosage. Typically, injections are prescribed in the acute period of various diseases, since with this method of administration the drug acts faster. In addition, it has less negative effects on the gastrointestinal tract. Since the positive effect after using injections is achieved faster, the drug begins to act within 15 minutes. Therefore, the duration of treatment may be shorter than with tablets. This reduces the risk of vitamin overdose.

This drug is available in tablets, dragees and solution for injection. Each Milgamma ampoule has a volume of 2 ml, which, in addition to water for injection and various auxiliary components, contains three B vitamins and lidocaine. These substances have a moderate analgesic effect, normalize the activity of the musculoskeletal system, participate in hematopoiesis, improve microcirculation and regulate the functioning of the nervous system. You can buy a package of Milgamma of 5 pieces or 10. A large package, sufficient for a full course of treatment, costs about 500 rubles, so the drug is available to every patient.

Reviews about the application

Many patients report positive results from this treatment. They write that they inject Milgamma every other day, and already in the second week of use the pain disappears and the mobility of the spine increases. Side effects after using the drug occur rarely, mostly patients describe local reactions. A burning sensation, irritation and pain may occur at the injection site, and a hematoma or lump may appear. The injections are quite painful, so patients, after the pain subsides, try to switch to taking pills or stop using the drug altogether.

Reviews from doctors about Milgamma are also mostly positive. But all experts note that the drug only relieves the symptoms of neurological pathologies. It cannot cure neuritis, neuralgia or osteochondrosis. Therefore, it must be used as part of complex therapy. And when used correctly, this remedy significantly increases the effectiveness of such treatment.

Analogues of the drug

Milgamma cannot be injected every day for a long time. But some patients require additional intake of B vitamins for longer than 10 days. In this case, the doctor may prescribe analogues of the drug, which also contain these vitamins, but not in such high concentrations. There are several drugs with similar composition and action. But they are less likely to cause symptoms of an overdose of B vitamins. Such drugs can be used to replace Milgamma:

• Vitaxon;
• "Combilipen";
• "Trigamma";
• "Binavit";
• "Neurobiks";
• "Neuromultivit";
• "Vitagamma";
• "Neuriplex".

These vitamin products are also available in tablets and injections. Only a doctor can decide what medicine the patient needs and in what form. Typically, injections are prescribed for pain or neurological problems. Before using any drug, be sure to read the instructions for it.

Features of action and results of injections

The composition of the drug "Milgamma" contains the main vitamins of group B. Thanks to their properties, this remedy is effective for many pathologies of the joints, spine and nervous system. This is explained by the effect that these vitamins have on the tissues of the body. After all, they stimulate the nervous system, improving neuromuscular conductivity. These vitamins normalize blood supply and nutrition to tissues, preventing degenerative processes in them. In addition, they stimulate metabolic processes, especially actively participating in the metabolism of fats and carbohydrates. This helps to improve the patient’s condition with various degenerative processes in the body, as well as inflammatory diseases of the joints and spine. The drug is able to relieve pain, reduce inflammation and swelling, and slow down destructive processes in cartilage tissue. All these effects are associated with the properties of its main components.

• Vitamin B1 is also called thiamine. It participates in carbohydrate metabolism processes, providing tissues with energy. In addition, it improves the conductivity of nerve fibers, normalizing the functioning of the nervous system. With the help of thiamine, the processes of restoration of nerve cells proceed faster.
• Pyridoxine or vitamin B6 is involved in the synthesis of many hormones and enzymes necessary for normal life. Under its influence, the body produces serotonin, dopamine, adrenaline, histamine, tryptophan and other substances. In addition, pyridoxine has a beneficial effect on the state of the nervous system and musculoskeletal system.
• Cyanocobalamin, better known as vitamin B12, is also important. It stimulates the synthesis of nucleic acids and some important enzymes. In addition to participating in metabolic processes, this vitamin can reduce pain caused by diseases of the nervous system or musculoskeletal system. After all, it is cyanocobalamin that stimulates the synthesis of the myelin sheath of nerves, which protects them from damage.
• Lidocaine in Milgamma is necessary to provide a local anesthetic effect. After all, these injections are very painful, and lidocaine reduces this discomfort.

Thanks to this composition, when used correctly, “Milgamma” significantly improves the condition of patients with various neurological pathologies, inflammatory diseases of the joints, and degenerative changes. The drug reduces pain and inflammation, stimulates nerve conduction processes, and restores the mobility of joints and the spine.

What does it help with?

People wonder in what cases the drug Milgamma is prescribed. The medication treats diseases and syndromes of the nervous system of various natures and is used as part of complex therapy. Indications for use of the solution:

• neuritis;
• neuralgia;
• paresis (paralysis) of the facial nerve;
• plexitis;
• ganglionitis (including herpes zoster);
• retrobulbar neuritis;
• neuropathy;
• polyneuropathy (including alcoholic, diabetic);
• night muscle cramps (especially in older people).

Milgamma injections are also prescribed for the back, for neurological manifestations of spinal osteochondrosis. Such disorders include radiculopathy, lumboischialgia, and muscular-tonic syndromes.

The benefits of the drug include relieving pain, improving blood circulation in damaged areas, and restoring nerve tissue.

With the permission of a doctor, the drug can be used for prevention.

Contraindications

The annotation indicates contraindications, in the presence of which the use of the solution may cause harm. They are:

• decompensated heart failure;
• age under 18 years;
• lactation;
• pregnancy.

If a person is intolerant to B vitamins, Milgamma is not suitable for an adult. The same applies to cases where there is hypersensitivity to the auxiliary components of the drug.

Mechanism of action of Milgamma

Milgamma is not one drug, but a set of three vitamins that are classified as neurotropic. Without them, normal functioning of the nervous system is impossible. These are B1, or thiamine, B6, or pyridoxine, and B12, or cyanocobalamin. Additionally, the complex drug contains 20 mg of local anesthetic - lidocaine, which makes intramuscular injection of vitamins painless. All these vitamins, from the manufacturer’s point of view, have a beneficial effect on inflammation, increase blood flow, and improve the metabolism of nervous tissue. Vitamins B1 and B6 potentiate each other, and cyanocobalamin takes part in the synthesis of the nerve sheath, consisting of myelin. After intramuscular injection, vitamins quickly enter the bloodstream and are distributed throughout the body.

Composition of the drug, physicochemical properties, price

The drug is available in two dosage forms: dragees (Milgamma compositum) and solution. The dragee is intended for oral administration, and the solution is intended for deep injection into muscle tissue. B vitamins stabilize the function of the central nervous system, activate blood circulation and have a mild analgesic effect.

Dragee	Solution
Main substance	100 mg vitamin B6 (pyridoxine hydrochloride); 100 mg benfotiamine	Vitamin B1 (thiamine hydrochloride): in 1 ml of solution - 50 mg or in 1 ampoule - 100 mg; Vitamin B6 (pyridoxine hydrochloride): in 1 ml of solution - 50 mg or in 1 ampoule - 100 mg; Vitamin B12 (cyanocobalamin): in 1 ml of solution - 500 mcg or in 1 ampoule - 1 mg; Lidocaine hydrochloride: in 1 ml of solution - 10 mg or in 1 ampoule - 20 mg
Excipients	Sodium carboxymethylcellulose, microcrystalline cellulose, aerosil, sucrose, povidone, talc, fatty acid glycerides, shellac, acacia powder, calcium carbonate, titanium dioxide, glycerol, polyethylene glycol -6000, corn starch, Tween -80, glycol wax	Benzyl alcohol - 40 mg, sodium polyphosphate - 20 mg, sodium hydroxide - 12 mg, potassium hexacyanoferrate - 0.2 mg, water for injection - up to 2 ml
Physicochemical characteristics	White dragee	Pink colored solution
Package	15 tablets in blister packs, 2 or 4 packs in a cardboard box	2 ml of the drug in dark glass ampoules, 5 or 10 ampoules in blister packs or cardboard trays, 1, 2 or 5 packs in a cardboard box
Price	30 dragees – 640-680 rub. 60 dragees – 1100-1440 rubles	5 amp. 250-280 rub. 1 amp. 470-550 rub.

Storage conditions and periods

The storage conditions of the solution must be observed for the effectiveness of the drug throughout the entire shelf life, i.e. for 3 years from the release date indicated on the package. Ampoules must be in their original packaging, at a temperature of +2...+8°C, in a place protected from sunlight. Freezing the medicine is prohibited.

The product should be stored where children and pets cannot reach it.

Interaction with other drugs and other types of interactions

Let's consider the following interactions of the main components of the drug and the results of these processes:

1. When vitamin B1 is mixed with solutions that contain sulfates , thiamine hydrochloride completely decomposes.
2. B1 also loses its medicinal properties in combination with the following substances: acetates, mercuric chloride, iodides, carbonates, vitamin B2 (riboflavin), tannic acid, ferric ammonium citrate, penicillin, metabisulfite, phenobarbital, dextrose.
3. The activity of thiamine hydrochloride decreases in the presence of copper (the catalysis process is enhanced) and the pH of the medium increases.
4. Vitamin B6 (pyridoxine hydrochloride) reduces the effectiveness of levodopa , so their combined use is prohibited.
5. Pyridoxine also interacts with cycloserine, isoniazid, and penicillamine.
6. Cyanocobalamin (vitamin B12) loses its activity when combined with heavy metal salts.
7. Vitamin B2 in combination with sunlight has a destructive effect on vitamin B12.
8. The combined use of norepinephrine, epinephrine or sulfonamides with lidocaine , which is part of the drug "Milgamma", leads to an increase in the effect of the latter on the heart.

Originally Answered: Which is better, calcium citrate or calcium carbonate? – read here.

Side effects

B vitamins are neurotoxic in overdose. They can negatively affect all systems of the body, especially the nervous system. Most often, side effects develop in those patients who are treated independently and do not know how to properly inject Milgamma intramuscularly. They may violate the treatment regimen, exceed the dosage, or not take into account the presence of contraindications. Usually, if the instructions are followed, the drug is well tolerated by patients. But if you inject Milgamma every day for a long time or exceed the dosage, side effects may occur. Negative reactions also develop when a preliminary tolerance test has not been carried out.

Side effects of the drug are most often associated with allergic reactions, as well as disruption of the cardiovascular or nervous systems. They can be like this:

• irritability, increased excitability;
• heart rhythm disturbances, up to cardiac arrest;
• heart pain;
• weakness, malaise;
• headaches, dizziness;
• convulsions, trembling in the limbs;
• breathing problems;
• blood clotting disorder;
• anemia;
• dermatitis, eczema, itchy skin;
• increased sweating, acne;
• runny nose;
• abdominal pain, vomiting, intestinal dysfunction.

More serious allergic reactions such as difficulty breathing, anaphylactic shock or angioedema are also possible. Most often they occur in those patients who did not take into account the presence of contraindications or the doctor’s recommendations on how many days to inject Milgamma.

The toxic effect of the drug is also enhanced if you drink alcoholic beverages during treatment. This is due to the fact that lidocaine is incompatible with ethanol. When they are used together, toxic damage to the liver and gastrointestinal tract develops, the patient develops restlessness, anxiety, drowsiness and headaches.

Only a specialist knows how to inject Milgamma intramuscularly to avoid negative reactions. Therefore, it is recommended to use the drug only after consulting a doctor. Rapid administration of the drug can cause heart rhythm disturbances, increased blood pressure, seizures and even fainting. Local reactions often also appear in the form of hematoma, pain and lumps at the injection site. If you inject into an arm or leg, you may experience cramps and numbness.

The drug Milgamma and its analogues

The active ingredients of the drug are B vitamins: B1 (thiamine), vitamin B6 (pyridoxine) and vitamin B12 (cyanocobalamin).

How to take Milgamma? For acute pain, a quick analgesic effect requires one injection of the drug Milgamma (2.0 ml), intramuscularly. For mild forms of the disease, the attending physician prescribes no more than 1 injection of Milgamma solution (2 ml) 2-3 times a week.

Milgamma tablets are intended for oral administration. Their composition is identical to the injection solution (B vitamins) and differs in the presence of excipients. Depending on the patient’s condition and his individual perception of certain components of the medicine, the doctor prescribes either tablets or injections of Milgamma.

The drug Milgamma has a wide analog range. These include medications such as Neuromultivit, Combilipen, Binavit. The international nonproprietary name of the active substance (INN) is the basic information about the drug. Drugs with the same active ingredients are produced under different trade names.

Side effects from taking the drug Milgamma - allergic reactions in the form of rash, itching, as well as increased sweating, dizziness, arrhythmia or convulsions - may appear if the drug is administered abruptly or if the dosage is not observed.

The drug Milgamma, the patent belongs to the Representative Office of VERWAG PHARMA GmbH{amp}amp;CoCG in Ukraine.

Manufacturer: Mauermann-Artsnaimitel KG, Germany. Heinrich-Knothe-Strasse 2, 82343 Peking, Germany.

Painful sensations experienced during human life, disorders of the nervous system should not be ignored, because in this way our body gives alarm signals. And this is a serious reason to turn to experienced specialists for advice and prescribe a course of treatment. Uncontrolled medication use and self-medication can lead to sad and unpredictable consequences.

At the Yusupov Clinic, the prevention and treatment of diseases of the nervous system and musculoskeletal system are successfully carried out under the supervision of leading doctors in the capital, thanks to high-tech equipment and widely used modern methods of medicine. More detailed information can be obtained from hospital consultants by making an appointment.

Pharmacies sell ampoules, dragees, and cream.

The remedy is a combination of three components: B1, B6, B12.

Thiamine (B 1) is a salt that is soluble in water. Its concentration in body tissues reaches 50% when taken orally.

He takes part:

• In providing pain sensitivity to the nerve, renewing damaged nerve fibers, promoting the signal along the sensitive endings;
• Protecting the cell membrane from the destructive effects of substances formed during oxidation;
• In the mechanisms of energy synthesis in the cell.

Benfotiamine is a fat-soluble salt of thiamine. It is absorbed almost 100% in the gastrointestinal tract, therefore it has advantages when taken orally compared to the usual water-soluble form.

Pyridoxine (Vit B 6):

• Improves metabolic processes in the nervous system;
• Antioxidant;
• Normalizes protein metabolism, prevents the accumulation of ammonia, a poison dangerous to nerve endings;
• Regulates amino acid metabolism.

Vitamin B 12 (cyanocobalomin):

• Used in the construction around the nerve ending of the myelin sheath;
• Regulates the processes of transformation of lipids, carbohydrates and proteins.

Milgamma tablets composition of vitamins:

• Benfiothiamine 100 mg;
• Pyridoxine (B6) 100 mg.

The work of milgamma is associated with the effects of the vitamins included in its composition. A person needs 2 mg of pyridoxine, thiamine, and 2 mcg of cyanocobalamin per day for a full life.

The amount of vitamins contained in the drug significantly exceeds a person’s need for them per day. Which explains their anti-inflammatory, regenerative and analgesic effect on peripheral and central nerve endings.

Lidocaine, an anesthetic, enhances the local anesthetic and trophic work of these vitamins. Using the drug together with a group of non-steroidal anti-inflammatory drugs enhances the analgesic effect and more effectively reduces inflammation.

The drug Milgamma is relatively expensive.

When using it, many note the absence of side effects and the fairly rapid achievement of the desired effect:

• Reduction or cessation of pain of any localization;
• Hair loss stops;
• Skin and nails look better;
• Many note an improvement in memory and mood;
• Weakness decreases.

Patients allergic to B vitamins and anesthetics report the appearance of rash and itching when starting to take the drug. Therefore, if you have not previously taken such substances, it is advisable to purchase a small amount of the drug and determine the presence or absence of an allergy.

Milgamma is a medicine with a pronounced analgesic effect. It is well tolerated when administered intramuscularly and orally. Has a wide range of indications. Should only be prescribed by a doctor.

The active ingredients of the drug are B vitamins: B1 (thiamine), vitamin B6 (pyridoxine) and vitamin B12 (cyanocobalamin).

The choice of the form of administration of this medication into the body depends on the individual characteristics of the patient, whether ampoules with a solution or tablets

The active ingredients of Milgamma injections are B vitamins: B1 (thiamine), vitamin B6 (pyridoxine) and vitamin B12 (cyanocobalamin), as well as lidocaine, which has local anesthetic properties.

Milgamma tablets are intended for oral administration. Their composition is identical to the injection solution (B vitamins - active substances benfotiamine 100 mg, pyridoxine hydrochloride 1) and differs in the absence of lidocaine hydrochloride and the presence of excipients.

https://www.youtube.com/watch?v=HJrzWhStYiY

Thiamine (B1) is responsible for normalizing carbohydrate metabolism in internal organs (liver, brain and living tissues). In addition, it is involved in the production of fatty acids and optimizes amino acid metabolism. An important function of thiamine is that it effectively reduces inflammation of the skin and improves the condition of the mucous membranes. Thiamine is involved in hematopoiesis and in the process of cell division, preventing the aging process of the body.

Thiamine is prescribed by specialists in the following cases:

• with liver disease;
• if the endocrine system is disrupted (consequences of obesity, diabetes);
• for eczema, psoriasis, pyoderma;
• in case of malfunction of the kidneys, brain and central nervous system;
• for gastritis, ulcers, pancreatitis and other gastrointestinal diseases.

Pyridoxine (B6) is a water-soluble element that regulates metabolic processes and normalizes blood circulation. Pyridoxine is involved in the synthesis of molecules and the breakdown of carbohydrates. In addition, vitamin B6 reduces the risk of obesity, diabetes and the development of cardiovascular diseases. The level of cholesterol in the human body depends on the amount of vitamin B6.

The role of vitamin B6 is indispensable in the synthesis of new red blood cells, i.e. this component is actively involved in the restoration of hematopoietic function. Like the other vitamins of the Milgamma complex, vitamin B6 affects the strengthening of the human immune system. In addition, a sufficient amount of pyridoxine protects against depression, relieves anxiety, and ensures calm.

Vitamin B6 is prescribed:

• patients with atherosclerosis, anemia and diabetes;
• pregnant women with toxicosis;
• teenagers with problems with improper functioning of the sebaceous glands.

Cyanocobalamin (B12) helps accelerate the breakdown of proteins, fats and carbohydrates. Responsible for the synthesis of leukocytes, which are involved in protecting living tissues from foreign elements. Reduces cholesterol levels in the human body. Vitamin B12 helps normalize sleep and optimize the production of melatonin, the sufficient amount of which determines the sleep-wake cycle.

Indications for the use of cyanocobalamin are as follows:

• radiculitis;
• cirrhosis of the liver;
• polyneuritis;
• skin diseases (dermatitis, psoriasis);
• radiation sickness;
• bone injuries;
• acute and chronic hepatitis;
• bone injuries;
• radiculitis and others.

By analyzing the totality of the complex of vitamins that make up Milgamma, you can understand the benefits this drug brings to the human body. It is the B vitamins that have a positive effect on the overall strengthening of the immune system and have a powerful therapeutic effect in the treatment of diseases of the central nervous system and musculoskeletal system.

Thanks to the use of Milgamma, specialists achieve quick relief from acute pain; the treatment brings a long-term positive effect. In addition, experts recommend taking Milgamma vitamins for various diseases of internal organs, since this replenishes the elements and nutrients that a weakened body lacks.

Milgamma is used in sports to enhance performance. Vitamin B1 is not an anabolic steroid and is not used for muscle growth. But it has an effect on the normalization of smooth muscle tone and the synthesis of amino acids. Athletes use vitamin B6 during intense training, and its use increases aerobic capacity by approximately 6-7% within a month.

This effect of vitamin B6 has a beneficial effect on achieving maximum results in weightlifters and bodybuilders. However, we should not forget that taking Milgamma is not recommended for people with problems with the cardiovascular system. And sports loads undoubtedly leave their mark on the functioning of the body.

Not all substances so necessary for the human body can be independently produced in sufficient quantities and successfully synthesized. The constantly deteriorating environmental situation is also not conducive to obtaining all the necessary minerals, vitamins and biologically active substances.

For an active and fulfilling lifestyle, modern people should not neglect the latest achievements of the pharmacological industry. It is the use of the Milgamma vitamin complex that will help achieve high results in saturating the body with much-needed B vitamins - thiamine, pyridoxine and cyanocobalamin.

Pharmacological properties of the main active ingredients

Vitamin B1 (thiamine hydrochloride). After this substance enters the body, phospholation processes occur. As a result, cocarboxylase and thiamine triphosphate are obtained from vitamin B1. And cocarboxylase, as an active metabolite, participates in the process of carbohydrate metabolism, improves conductivity in the nerves, and this is how the functions of the nervous tissue are normalized.

With a lack of thiamine in the body, carbohydrate metabolism products accumulate, and the development of various pathological conditions is provoked.

Vitamin B6 (pyridoxine) is phospholated in the same way as thiamine. During its metabolism, substances are formed that participate in the decarboxylation of amino acids.

As a result, the body produces very important mediators:

1. Adrenaline.
2. Histamine.
3. Tyramine.
4. Dopamine.
5. Serotonin.

Vitamin B6 is also involved in the metabolism of the aromatic alpha amino acid tryptophan. The combination of thiamine and pyridoxine is very important, since they improve the effect of each other.

Vitamin B12 (cyanocobalamin) is involved in the following vital processes of activation of synthesis:

1. Nucleic acids.
2. Choline.
3. Creatinine.
4. Methionine.

It also helps:

1. Reduce pain that occurs with lesions of the peripheral nervous system.
2. Go through the process of cellular metabolism.
3. Prevent the development of anemia.

Cyanocobalamin, entering the blood plasma, binds to albumin, does not accumulate in body tissues, and is excreted in the urine. Since it has the ability to penetrate the blood-placental barrier, vitamin B12 is prescribed with caution during pregnancy.

Lidocaine is used as part of the drug for a local anesthetic effect , since intramuscular administration of this vitamin complex is quite painful.

Analogues of the drug Milgamma: price, reviews

The drug Milgamma has a wide analog range. Thus, such drugs as Neuromultivit, Combilipen, Binavit are similar in their composition and pharmacodynamic properties to Milgamma. The main active ingredients of these drugs are the group of B vitamins. The presence of B vitamins in these drugs makes them equivalent for the treatment of neurological disorders, vegetative-vascular dystonia and a number of other diseases. However, depending on the country of manufacture, the cost of drugs also fluctuates. Therefore, the advantage of analogues of the drug Milgamma in some cases is that for budget-conscious people they are more affordable and acceptable options.

Interaction of the drug with other medications

When Milgamma is used simultaneously with other substances, vitamin B1 undergoes complete breakdown in the body and does not provide proper treatment. In addition, any other elements cease to act; for this reason, a therapeutic effect cannot be expected in this situation.

The lack of the required effect from therapy occurs due to the interaction of vitamin B1 with the following components and substances:

• Magnesium sulfate or otherwise magnesia is a medicinal product that has a laxative, choleretic, sedative, antispasmodic, vasodilator, anticonvulsant, hypotensive and antiarrhythmic effect.
• Mercuric chloride or Sublimate serves as an antiseptic and disinfectant. According to reviews, the use of "Milgamma" should be careful.
• Potassium iodide is used to treat overactive thyroid gland, endemic goiter, as well as hyperthyroidism, syphilis, eye and respiratory tract pathologies.
• Riboflavin and glucose.
• Ferrous ammonium citrate or otherwise food additive E381, as well as antioxidants and antioxidants.
• Acetates, simply put, are esters, as well as salts of acetic acid.
• Tannic acid, which is a fairly common component among many drugs.
• Lithium carbonate, which is a strong antipsychotic and sedative used for such phenomena as schizophrenia, chronic alcohol dependence, manic disorders, and so on. The composition of vitamins in Milgamma in mg must be taken into account.

In addition, the activity of vitamin B1 may decrease as a result of an increase in the acid-base balance in the human body, and, in addition, due to interaction with drugs that contain copper.

The influence of vitamin B6 reduces the effectiveness of drugs aimed at combating Parkinson's disease. For this reason, you should not use such drugs at the same time. Some heavy metal salts can deprive the vitamin of its beneficial functions and properties.

This is confirmed by the instructions for use of "Milgamma" and reviews.

Drug analogues

Milgamma is produced by the German company Ferwag-Pharma, it is produced in ampoules of 2 milliliters, used only intramuscularly, there are three packaging options - 5 ampoules, 10 and 25. Accordingly, the medicine can be designed for a long course of treatment. The cost of the most popular package - 10 ampoules - ranges from 405 to 730 rubles.

Milgamma is a popular drug in the CIS countries, and it has quite a lot of imitators. These include:

• Binavit;
• Vitaxon;
• the more famous and widely used Kombilipen;
• Compligam B;
• Larigama.

Binavit is a domestic drug produced by the Armavir biofactory with a price for a similar package of 239 rubles. Combilipen is a drug from Pharmstandard, with an average cost of 270 rubles. Compligam B is produced by the domestic company Sotex, with an average cost of 250 rubles, and Larigama is produced by the Russian company Grotex LLC, and its cost is approximately 260 rubles per package.

Attention. There is also the drug Milgamma compositum, which has a slightly different effect. Firstly, it contains only one vitamin B6, and benfotiamine, a derivative of vitamin B1, and secondly, it is available in tablets and is more expensive, that is, it does not have a form for parenteral administration.

There is also the drug Milgamma compositum, which has a slightly different effect. Firstly, it contains only vitamin B6 and benfotiamine, a derivative of vitamin B1, and secondly, it is available in tablets and dragees, it does not have a form for parenteral administration. Accordingly, the drug Milgamma can be considered more effective because it contains vitamin B12, or cyanocobalamin.

A deficiency of this vitamin can lead to a neurological disorder such as sensory or posterior columnar ataxia. In this case, the pathways of the joint-muscular sense lying in the posterior columns of the spinal cord are affected. They carry proprioceptive sensitivity, or muscle-joint sense, to the brain for analysis. Thanks to the work of this analyzer, we can be aware in complete darkness where our limbs are, and when walking on a flat surface in the dark, we do not fall, because we know how our legs are rearranged and where our torso is. With posterior columnar ataxia, this sensation is blurred or lost altogether. Therefore, one of the characteristic clinical symptoms will be a fall, or an unsteady gait of patients at night, for example, when getting up to go to the toilet. The patient should walk in good light to see the position of his legs.

If such symptoms are present, it is very likely that there is a deficiency of vitamin B 12, since sensitive ataxia is a characteristic sign of deep pernicious anemia.

Basic rules of application

It is advisable that such injections be performed by a person with medical education. But still, the patient himself needs to learn how to inject Milgamma correctly. Due to the characteristics of the drug, there are some subtleties in its use. If they are not taken into account, this will increase the risk of side effects and may worsen the patient's condition. There are several rules for using this drug; they are not always indicated in the instructions, so consultation with a doctor is still required.

• First of all, you need to know that Milgamma can only be injected intramuscularly. It is undesirable for the components of the product to enter directly into the blood, as this can cause dangerous reactions from the cardiovascular system.
• It is necessary to inject the drug as deeply as possible, then it will work faster and better. In addition, this will avoid the drug getting into the bloodstream and nerve fibers, which is not very good. Depending on the patient’s build, you need to be able to choose the right needle length.
• "Milgamma" is an oily solution. Therefore, its passage through a thin needle may be difficult. Those who do not know how to inject Milgamma intramuscularly may have problems. For proper injection behavior, it is important to choose a needle of medium thickness.
• For the same reason, the solution slowly spreads in tissues. Therefore, it is recommended to lightly massage the injection site after the injection. This will increase the effectiveness of treatment and also avoid the appearance of bumps and hematomas.
• It is also important to know how to inject Milgamma correctly at the right time. The drug must be administered slowly, over at least 1.5-2 minutes. To do this, press the syringe plunger smoothly. This will reduce the pain of the injection.
• Every day, injections should be given in different places, the distance from the previous injection should be at least 2-3 cm. If a lump appears at the injection site, be sure to do compresses with magnesium or warming procedures.
• During treatment, it is necessary to monitor the patient's blood composition. This will help avoid anemia, which is a common reaction to long-term use of the drug. And due to the presence of lidocaine, you also need to monitor your heart function.

Patients about Milgamma injections (reviews): are the injections painful?

It should be noted that the opinions of patients here are divided. This depends on the individual characteristics of the body, on each patient’s perception of pain. Milgamma contains lidocaine, which is a strong local anesthetic. Some patients may experience skin irritation at the injection site, but this phenomenon is quite rare and depends on the patient’s individual tolerance to the components of the drug. Reviews about the drug Milgamma tablets are sometimes more positive than about injections. Doctors are often asked the question: what is better - Milgamma tablets or injections? The answer from doctors is this: the use of injections is more effective in the presence of systemic diseases, while tablets are good for maintenance therapy and for preventive purposes. In any case, the right to choose the form of the medicine should always remain with the treating specialist.

Registration numbers

solution for intramuscular administration 100 mg+100 mg+1 mg+20 mg/2 ml: amp. 5, 10 or 25 pcs. P N012551/02 (2003-11-06 – 2003-11-11)

Experimental determination of suitable drugs:

• NEUROGAMMA
• COMPLIGAMV
• TRIGAMMA
• MILGAMMA COMPOSITUM
• COMBILIPEN
• KETOROLAC
• FLAMAX
• VITAGAMMA
• THIAMIN
• DOLOMIN
• PENTOVIT
• NEUROBION

Add a comment Cancel reply

ATX code for MILGAMMA

A11DB (Combination of vitamin B1 with vitamins B6 and/or B12)

Experimental determination of suitable drugs:

• NEUROGAMMA 17.006 (B complex of vitamins), Solution for…
• COMPLIGAMB 17.006 (B complex of vitamins), Solution for…
• TRIGAMMA 17.006 (Vitamin B complex), Solution for…
• MILGAMMA COMPOSITUM 17.006 (B complex of vitamins), White dragee…
• KOMBILIPEN 17.006 (Vitamin B complex), Solution for…
• KETOROLAC 05.002 (NSAID with a pronounced analgesic effect), Solution…
• FLAMAX 05.001 (NSAID), Solution for intravenous and intramuscular…
• VITAGAMMA 17.006 (Vitamin B complex), Solution for…
• THIAMIN Clinical and pharmacological groups 17.002 (Vitamin of group B) 17.024 (Multivitamins with macro- and microelements and amino acids) 29.078…
• DOLOMIN 05.002 (NSAID with a pronounced analgesic effect), Solution…
• PENTOVIT 17.006 (Vitamin B complex), Tablets, coated…
• NEUROBION 17.006 (B complex of vitamins), Solution for…

Release form, composition and packaging

The solution for intramuscular administration is transparent, red.

1 ml	1 amp.
thiamine hydrochloride (vit. B1)	50 mg	100 mg
pyridoxine hydrochloride (vit. B6)	50 mg	100 mg
cyanocobalamin (vit. B12)	500 mcg	1 mg
lidocaine hydrochloride	10 mg	20 mg

Excipients: benzyl alcohol, sodium polyphosphate, potassium hexacyanoferrate, sodium hydroxide, water for injection.

2 ml - dark glass ampoules (5) - blister packs (1) - cardboard packs. 2 ml - dark glass ampoules (5) - blister packs (2) - cardboard packs. 2 ml - dark glass ampoules (5) - cellular contour packaging (5) - cardboard packs. 2 ml - dark glass ampoules (5) - cardboard pallets (1) - cardboard packs. 2 ml - dark glass ampoules (5) - cardboard pallets (5) - cardboard packs. 2 ml — dark glass ampoules (10) — cardboard pallets (1) — cardboard packs.

Milgamma: benefits and harms during pregnancy

https://www.youtube.com/watch?v=upload

Experts advise taking the drug during pregnancy if symptoms such as:

• neuritis;
• radicular syndrome;
• paralysis, spasms, muscle numbness;
• herpes, in which the percentage of body damage is more than 60%;
• infectious, bacterial diseases;
• periodic disorders that occur in pregnant women due to a lack of vitamin B;
• weak immunity caused by insufficient amounts of vitamins in the body.

Can Milgamma cause complications in pregnant women?

Experts warn that when undergoing a course of treatment with Milgamma, contraindications for pregnant women may be as follows:

• You should not take the Milgamma complex if you have acute intolerance to one of the components of the drug;
• It is not advisable to take tablets or give injections of this medicine while breastfeeding;
• the use of the drug for problems with the heart muscle is excluded;
• if you have problems with the digestive system, poor metabolism, hormonal disorders;
• thrombosis, vein blockage, atherosclerosis.

Pregnant women, in addition to such side effects as an allergy to Milgamma in general, poor health, itching, burning, skin rashes, fever, general malaise, nausea, swelling, may also be in danger of stopping the development of the fetus.

Drug interactions

Often this drug is prescribed as part of a complex treatment. In this case, you must inform your doctor if you are taking other medications. Only a specialist knows whether Milgamma can be injected simultaneously with other drugs. Some medications may cause treatment to be less effective or increase the risk of side effects.

The effectiveness of the drug will decrease if the patient takes diuretics, oral contraceptives, antiparkinsonian drugs, Isoniazid, Cycloserine, Penicillamine and some other drugs. The components of the product will be completely destroyed or stop working when combined with sulfate solutions, iodides, riboflavin, iron citrate, and Penicillin. Conversely, Milgamma can reduce the effect of sleeping pills, sedatives, cardiac glycosides, Levodopa and anesthesia drugs.

There are also medications whose effectiveness increases when used simultaneously with this remedy. This is due to their compatibility with lidocaine in its composition. Because of this, the effectiveness of Novocaine, adrenergic blockers, antiarrhythmic drugs, Cimetidine, anticoagulants and narcotic analgesics increases. Therefore, this drug is often prescribed together with other medications with which it is compatible. Especially often these are non-steroidal anti-inflammatory drugs or painkillers, for example, Movalis. With this treatment, pain and inflammation decrease faster, and the mobility of the spine and joints increases. But you need to understand how to inject Movalis and Milgamma intramuscularly correctly. Only a doctor can prescribe the required dosage, regimen and duration of treatment.