Ursosan for pancreatitis, expert opinion


The main effect of the drug and its effectiveness in pancreatitis

The drug is manufactured in the Czech Republic in the form of capsules, which are in blisters of 10 pieces. The number of blisters in a box varies from 1 to 10.

The main component of Ursosan is ursodeoxycholic acid. This component has the ability to interact with toxins and suppress their functions, forming beneficial compounds. This function protects liver cells, penetrating into tissues, and prevents the negative effects of acid found in bile.

Ursosan for pancreatitis acts as follows:

  1. Protects the liver from the toxic influence of external and internal factors - the consequences of taking medications, breakdown products of substances contained in alcohol, and the influence of environmental irritants.
  2. Improves the outflow of bile and promotes rapid passage through the intestines.
  3. Reduces lipidity. Significantly lowers cholesterol levels.
  4. Promotes self-resorption of kidney stones and inhibits their appearance.
  5. Strengthens the resistance of liver cells, normalizes the functioning of lymphocytes and prevents varicose veins in the esophageal veins.

Often, the causes of pancreatitis are developmental disorders and diseases of the genitourinary system, liver and alcohol addiction. They contribute to the appearance of alcoholic and biliary pancreatitis, which are chronic and characterized by seasonal exacerbations.

These reasons are a reason to prescribe Ursosan for the pancreas, because these pathologies contribute to the exacerbation of pancreatitis and complex therapy is required to eliminate symptoms.

Drug analogues


Analogues of Holosas for their choleretic effects include the following medications:

  1. Allohol.
  2. Cynarix.
  3. Artibel.
  4. Artichol.
  5. Artichoke extract.
  6. Hepabel.
  7. Gepar.
  8. Flamin.
  9. Gepabene.

It should be noted that these medicines have different, but mostly herbal compositions. However, their direction of influence is similar: improving the outflow of bile, normalizing the functioning of the liver, protecting its cells from the irritating effects of toxins, stimulating peristalsis of the stomach and intestines. In addition, the drugs have a mild anti-inflammatory, antibacterial, and healing effect.

The medicine is replaced with an analogue if it turns out to be ineffective in a particular case or the patient begins to develop allergic or adverse reactions. The decision on the need to replace the medication and the choice of a suitable analogue should be made exclusively by the doctor. Under no circumstances should you arbitrarily replace prescribed funds.

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For what diseases can Ursosan be prescribed?

The drug is prescribed by a specialist strictly according to indications, and is recommended in the following cases:

  • Presence of gallstones;
  • Prevention of stone formation;
  • Manifestations of acute hepatitis;
  • Active form of hepatitis;
  • Cystic fibrosis of the liver;
  • Carrying out preventive measures to cleanse and protect the liver;
  • Primary cholangitis.

Composition and release form

The medicine is a thick dark brown syrup prepared from a condensed aqueous extract of rose hips and sugar. Standard packaging is 140 and 300 g, the syrup is bottled in dark glass bottles.

The inclusion of Holosas in the treatment regimen for pancreatitis will not only improve the production of bile acids, but also enhance intestinal motility.

Possible side effects from the administration of the medicine

With proper administration and dosage, as well as using the drug as directed, the possibility of side effects is minimal. But in some cases they are possible. Side effects of the drug include:

  • diarrhea - can be caused by a lack of acceptance of ursodeoxycholic acid;
  • allergic reactions - skin rashes, burning;
  • nausea or vomiting;
  • hair loss;
  • increased levels of liver enzymes;
  • the appearance of calcium salts in gallstones.

Rare side effects include sudden hair loss, possibly complete or partial. If this problem occurs, you should stop taking the drug and seek advice from the doctor who prescribed the drug.

In what cases do doctors prohibit taking the drug?

Some patients think that they can take Ursosan on their own and pancreatitis will disappear, but in fact there are a number of serious contraindications.

These include:

  • inflammatory processes in acute form, but since ursosan has a very positive effect on the pancreas, use is allowed in the chronic phase of the disease;
  • individual sensitivity to the components of the drug;
  • the appearance of large stones in the bladder and cholelithiasis, which can cause colic;
  • the appearance of calcium salts;
  • formation of internal fistulas;
  • pathologies of the bladder;
  • inflammatory diseases of the body;
  • obstruction of the bile ducts;
  • cirrhosis of the liver;
  • renal failure.

Women are also often concerned about the question of whether Ursosan can be taken for pancreatitis during pregnancy and breastfeeding. It is contraindicated to use this drug during this period, as it can adversely affect the fetus by penetrating the placenta and breast milk.

It can be prescribed only in extreme cases, if there is a great danger to the mother's health.

Pharmacological properties of the drug


Holosas is a choleretic agent. The main effect of the medicine on the body is to activate the production of bile, reduce its viscosity and normalize the outflow. In this case the drug:

  1. Activates liver function.
  2. Increases the amount of bile salts.
  3. Increases the secretory activity of the stomach and pancreas.
  4. Strengthens intestinal motility.
  5. Has a mild diuretic effect.

The medicine consists of rosehip extract, contains vitamins A, B, C, E, K, organic acids, flavonoids, pectins, essential oils. Thanks to this composition the medicine:

  • has a mild anti-inflammatory effect;
  • strengthens the immune system;
  • activates the secretion of bile and digestive enzymes;
  • improves appetite;
  • activates digestive and metabolic processes;
  • has a particularly beneficial effect on carbohydrate metabolism;
  • prevents the development of suppuration processes or reduces their severity.

The constituent components of the drug promote the regeneration of damaged cells, increase the body's protective functions and its resistance to pathogenic microorganisms.

Effect on the pancreas


Holosas for the treatment of the pancreas is prescribed in cases where inflammation of the organ is provoked or accompanied by a violation of the outflow of bile, its reflux into the pancreas ducts, or cholecystitis.

It should be noted that it is the stagnation of bile that often becomes the cause of an acute attack of pancreatitis or exacerbation of chronic inflammation of the gland.

If the outflow of bile is disrupted, it cannot enter the small intestine and is thrown into the pancreatic ducts, clogging them. For this reason, digestive enzymes cannot pass through the ducts into the intestines - they remain in the gland, are activated in it and begin to digest organ tissue.

In addition, as a result of the accumulation of bile masses, the pressure inside the ducts increases, small ducts rupture, bile spills onto nearby tissues, including the pancreas, which leads to their inflammation.

Holosas for pancreatitis:

  • facilitates the outflow of bile;
  • reduces the viscosity of bile masses;
  • prevents the formation of stagnation.

Thanks to this, the pancreatic ducts are cleared, and the passage of digestive enzymes from the parenchymal organ into the intestine is resumed. This helps reduce the secretory load on the gland and restore the functioning of the organ.

Stopping the effusion of bile on organ tissue as a result of rupture of the ducts also helps to reduce the severity of the inflammatory process and swelling. Due to the resorption of stagnation, the pressure on the organs of the digestive tract is reduced. All these processes lead to improved digestion, metabolism and normalization of the functioning of all organs of the digestive tract. As a result, the health of the patient with pancreatitis improves: colic, flatulence, bloating, and heartburn disappear.

Thanks to the content of vitamins and flavonoids, the medication strengthens the protective functions of the pancreas and its resistance to bacteria and infections. This is very important, since when the gland is inflamed, the immune system suffers greatly.

Composition of the drug


The advantage of the medicine is its natural plant content. The functioning component of the medicine is rosehip extract. The drug also contains water and sugar.

Rose hip extract is enriched with:

  • vitamins A, B, C, E, PP;
  • flavonoids;
  • essential oils;
  • calcium;
  • potassium;
  • magnesium;
  • iron;
  • organic acids.

Cost and release form

The medicine is produced in the form of a thick syrup, which has a rich brown color and a specific odor.

The medicine can be found in bottles with a capacity of 140 and 300 ml. Price 140 ml. bottle is 85-100 rubles, cost 300 ml. containers – 190-210 rub.

Dosage and features of use of Ursosan

Before taking Ursosan for pancreatitis, you should definitely be examined by a doctor. The specialist will determine the extent of the disease, the causes and eliminate the risk of complications, and also prescribe an individual dosage in complex or single therapy.

The medication should be taken internally with a small amount of liquid, during meals or after eating.

The dose is prescribed individually and depends on the disease and its degree. In most cases, the following dosage is used:

  1. In the presence of diseases accompanied by inhibition of the functions of the genitourinary system - 1-2 tablets, 2 times a day, the course can be either 14 days or 2 months.
  2. In the case of cystic fibrosis, cirrhosis or sclerosing cholangitis - 2-3 tablets per day for six months, sometimes treatment can last for several years.
  3. After bladder surgery - 1 tablet at night for 14 days, sometimes six months.
  4. If the patient has chronic hepatitis or liver failure caused by prolonged alcoholism, split 1-2 tablets into 3 doses. The therapeutic course lasts from six months to several years.

If the patient takes the drug for more than a month, then in this case he must donate blood for biochemical analysis once every 3-4 weeks. It determines the activity of liver enzymes. And also with long-term therapy, ultrasound of the bladder and urinary tract every six months is mandatory.

Indications and rules of admission

Ursosan is actively used for pancreatitis, as well as in a number of other cases. Indications for its use are:

  • gallbladder diseases;
  • pathologists of the biliary tract;
  • pancreatitis;
  • cholestatic phenomena in the liver;
  • hepatitis of various etiologies;
  • cirrhosis of the liver;
  • alcohol intoxication and other types of poisoning;
  • cystic fibrosis;
  • during surgical interventions in the gastrointestinal tract.

Also, this medicine can be prescribed as a preventive course for alcohol abuse, living in a polluted environment, or harmful working conditions.


Taking Ursosan helps reduce the negative effects of alcohol on the digestive organs

Despite the natural origin of the drug, as well as a lot of positive effects from its use, it can be introduced into the general treatment regimen only after consulting a doctor. The dosage and duration of the course are determined based on studies of the patient’s health status and in relation to the established diagnosis.

You need to take Ursosan according to a special regimen, which depends on the presence of concomitant diseases.

The dosage is determined either according to standard indicators for a specific disease, or based on calculations of the portion of the active substance per 1 kilogram of the patient’s weight. The drug is available in the form of capsules, each of which contains 250 mg of ursodeoxycholic acid.

Ursosan can be used for long-term therapy if there are no corresponding contraindications. In addition, you will need to periodically undergo additional examinations to monitor the results of treatment.


If you take Ursosan for a long time, you must periodically visit your doctor and monitor test results.

Interaction with other medications

There are Ursosan substitutes with similar functions. The most popular:

  • Ursolfak, which contains ursodeoxycholic acid, classified as a hepatoprotector with the ability to dissolve cholesterol gallstones;
  • Urdoxa with the same active ingredient, characterized by a powerful choleretic effect and a high ability to relieve side effects from other drugs and the consequences of the disease;
  • Ursorom S, like the previous drug, has a choleretic and cholelitholytic effect;
  • Ursodeoxycholic acid.

Contraindications

Ursosan has a list of contraindications. These include:

  • acute inflammation of the liver or gall bladder (cholangitis, cholecystitis);
  • excessive calcium content in gallstones;
  • gallstones more than 1.5-2 cm in length;
  • lack of contractions in the gallbladder;
  • blockage of gallbladders, obstruction;
  • development of empyema in the gallbladder;
  • the appearance of a fistula in the stomach, gall bladder, intestines;
  • liver cirrhosis in decompensated form;
  • renal failure;
  • allergic reaction to individual components of the drug.

The drug helps, usually in the initial stages of pancreatitis.

Particular attention when prescribing Ursosan is given to children aged 2 to 4 years, ulcers and people with hepatitis, cirrhosis of the liver or cholestasis of the liver. In these cases, the drug is prescribed with great caution; the prescription depends on the individual characteristics of the patient.

Reviews about the drug

Among the reviews about the drug, there are many positive responses regarding the effectiveness of Ursosan. The negative aspects include the high cost of the product and the need for a long course of treatment.

Ursosan effectively helps with disorders of the glandular mucosa after a course of strong antibiotics or chemotherapy substitutes. There are positive reviews about the effectiveness of the drug in the treatment of elderly patients who, due to their age, constantly have to take medications that have a detrimental effect on the condition of the liver.

Ursosan not only allows you to fight the underlying disease, for example, pancreatitis, but also effectively eliminates the source that caused it.

Patients say that as a result of treatment with Ursosan, pancreatitis recedes for a long time, inflammatory processes are stopped, the number of relapses decreases and the liver is gradually restored.

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