Use of Pimafucin for thrush: indications, effectiveness

Pimafucin is a medicinal antifungal drug based on natamycin (a substance that inhibits the growth and reproduction of fungal infections). In fact, the product is an extended profile antibiotic (macrolide group), equally effective against candidiasis and perfect fungal infections.

Prescribing Pimafucin for thrush has a number of advantages:

• manufactured forms of the drug allow for complex treatment of thrush in its various manifestations;
• The product is universal, suitable equally for women and men, and, subject to dosage, can also be used for children;
• the medicine is of local importance only, and therefore does not affect the system.

Vaginal candidiasis

This disease is one of the most common in the field of gynecology today. The so-called thrush is a fungal infection of the vaginal mucosa, which is caused by fungi of the genus Candida. The disease can occur under the influence of a wide variety of factors, which include a decrease in general immunity, unprotected sexual intercourse, taking antimicrobial drugs and antibiotics. Almost every woman faces this problem at different stages of life. For many, this may be associated with the onset of menstruation or frequent stress.

Almost every person is a carrier of the fungus, but its amount in the body must meet certain standards. However, in cases where the fungus begins to actively reproduce, a woman experiences symptoms such as a sharp burning sensation in the external genital area and severe itching. The main feature of thrush, which distinguishes it from other inflammatory and infectious diseases of the genital organs, is a specific discharge similar to a curd mass. Such symptoms disappear, as a rule, already in the first days of treatment, however, to achieve a stable and long-term effect, it must be carried out in a course of at least 10 days, together with a sexual partner.

Let's look at how Pimafucin suppositories work. Analogues will be presented below.

Instructions for use of Pimafucin tablets for thrush

Tablets are more versatile and are suitable for adults and children over 6 years of age. They are prescribed for problems (infectious) of the gastrointestinal tract, as well as for candidiasis of the colon. The uniqueness of the medicine consists of the content (ingredients) and high-quality enteric coating.

In addition to natamycin, the composition includes:

• starch and lactose;
• magnesium stearate and cellulose acetate phthalate;
• talc, gelatin and natural beeswax.

In addition, there are a number of relatively simple chemical compounds based on titanium (as a binder for antiseptic and blood hemoglobin) and calcium (in this case, calcium carbonate).

Judging by the composition, the likelihood of allergic reactions increases to 3.5–6%, mainly due to beeswax and lactose.

The intake should be exclusively a course of 200 mg per day (2 full tablets) for 2 weeks (the course can be extended to 4 weeks as prescribed by a doctor).

Use by children is possible in half the dosage, but not at one time, but always divided into 2 times.

Pharmacological properties of the drug

The main active ingredient of the drug is natamycin (an antibiotic belonging to the macrolide group). This substance is capable of actively reacting to the cell membranes of yeast-like fungi, which contributes to their destruction and death. In addition, natamycin is active against some other pathogenic microorganisms that can cause vaginal dysbiosis and thrush. Pathological bacteria such as dermatophytes are also sensitive to this active substance.

When applied topically in the form of suppositories, the drug “Pimafucin” is not absorbed into the blood, which does not cause any systemic disturbances in the functioning of the entire body.

In addition to the main active ingredient, vaginal suppositories also contain auxiliary ingredients - lactose, potato starch, gelatin and others.

Indications for use

Indications for use vary depending on the chosen form of release.
Tablets are used for intestinal candidiasis, acute atrophic and pseudomembranous candidiasis, immunity disorders, after treatment with cytostatics, antibiotics and hormonal agents, fungus of the skin and mucous membranes, for example, vaginal candidiasis.

The cream is used for fungus of the mucous membranes and skin. It is effective if the fungus is sensitive to the active component. It is also used for external otitis and skin fungus, onychomycosis, dermatomycosis, balanoposthitis, vulvovaginitis.

Suppositories are used to treat fungus of the genital mucosa. They are mainly used for the treatment of vaginal candidiasis.

Directions for use and dosage

For any infectious and inflammatory diseases of the genital organs, the drug is prescribed once a day. The medication is intended for treatment in a course, and its duration should be at least three days for a mild course of the disease, and less than six days for an average course.

To achieve the maximum effect, it is recommended to carry out treatment for several more days after the end of the main therapy, even in cases where the disease is asymptomatic.

The product should be used topically, by inserting into the vagina to the maximum depth, while taking a horizontal position of the body. This should be done once, before going to bed. This is confirmed by the instructions for use for Pimafucin. Analogues of candles are usually used in the same way.

For systematic recurrent manifestations of vaginal candidiasis and other diseases that are provoked by the proliferation of pathogenic microorganisms, it would be advisable to take an antifungal drug orally in the form of tablets against the background of the main treatment with vaginal suppositories. The duration of such a course must be at least 10 days. Tablets are necessary to destroy foci of infection in the intestines, which may be chronic.

Particular attention should be paid to the fact that treatment should be carried out not only for the patient, but also for her sexual partner, since he can also be a carrier of the infection. To treat your partner, you can use the drug “Pimafucin” in the form of a cream, which should be applied to the genitals several times a day. The duration of the course of such treatment varies depending on the degree of the disease and is determined in each case individually.

Is it possible to use Pimafucin suppositories and analogues during pregnancy? Let's look at it below.

special instructions

1 tablet of Pimafucin contains 66 mg of lactose monohydrate and 122 mg of sucrose. Before using the drug in this dosage form, patients with rare congenital galactose/fructose intolerance, sucrase-isomaltase deficiency, glucose-galactose malabsorption, lapp lactase deficiency should definitely consult a doctor.

Suppositories should not be used during menstruation.

There is no need to avoid sexual intercourse during treatment with suppositories. However, it is necessary to examine both sexual partners and carry out a course of therapy if candidiasis is detected. In addition, barrier contraception should be used.

Pimafucin does not affect the speed of reactions and the ability to concentrate.

According to indications, the drug can be used during pregnancy and lactation.

• The use of the drug during pregnancy and breastfeeding is possible, but requires medical supervision and a complete absence of side effects. The active substance does not pass into breast milk.
• In childhood, there is a restriction on the dose of the drug taken: children under 5 years of age are prescribed half the dose of Pimafucin.

To achieve the maximum therapeutic effect, both partners should be treated with the drug, with the man prescribed Pimafucin in the form of a cream. During therapy, it is best to refuse sexual relations.

In case of frequently recurrent fungal disease or chronic pathology, Pimafucin suppositories should be combined with Pimafucin in tablet form.

Women during menstruation are not treated with the drug; if the patient is due to start her period any day, then it is best to postpone therapy until the end of her critical days.

Since vaginal discharge may increase during treatment with suppositories, disposable pads should be worn for hygiene. Active and auxiliary substances of suppositories can negatively affect latex products, which should be reported to patients who do not want an unplanned pregnancy.

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Due to the lack of experience in use and the unproven safety of the drug among persons under 16 years of age, Pimafucin suppositories are not prescribed to girls under this age.

Side effects

Side effects of this medication may include mild itching and burning in the genital area, as well as minor irritation of the mucous membranes of the vagina. This effect may be due to the fact that the drug contains cetyl alcohol as an excipient. Despite the occurrence of symptoms associated with side effects, interruption of treatment is not recommended. Another side effect from the use of vaginal suppositories is that in the first days of treatment, the symptoms of thrush may worsen slightly, but this also should not be a reason to stop therapy. This indicates instructions for the Pimafucin suppositories. Analogues should be selected by a doctor.

Pimafucin suppositories: instructions for use for women with thrush

The composition of the suppositories differs in terms of excipients (solid fat, cetyl alcohol, sorbitol and polysorbate, as well as adapic acid). This composition is necessary to retain the solid form during administration and slow dissolution (for the gradual release of the main drug and its more complete absorption).

Only women can use suppositories, since their administration is indicated as vaginal.

The drug is used to treat fungal, viral and bacterial infections in the urogenital system of the female body (urethritis, ureaplasmosis, partially cystitis and thrush).

Taking suppositories for thrush in women should be a course, depending on the severity of the infection, it can last from 7 to 28 days with a frequency of 2 suppositories per day (for polycandidiasis, 3 times the use is possible).

Correct insertion of the suppository is considered important - it is inserted with the extended part forward to a depth of 5-7 cm and remains in the woman’s vagina until completely dissolved (during the procedure, you must be in a supine position, preferably on your back). Immediately after the procedure, be sure to use sanitary pads, as slight discharge is quite possible (this is quite natural).

Candle price from 175 rubles. If you want cheaper analogues, then pay attention to Ecofucin, it is a little cheaper, from 111 rubles.

Analogues of Pimafucin suppositories

In pharmacies you can find medications that contain the same active ingredient. They are Primafungin, Natamycin and Ecofucin.

In addition, there are a number of medicines that are not analogues of Pimafucin suppositories for thrush, but have similar pharmacological effects. These include:

• "Betadine."
• "Terzhinan."
• "Fluomizin."
• "Livarol."
• "Polygynax".
• "Miconazole".
• "Zalain."

What is the best price to buy analogues for Pimafucin suppositories? The following products will be cheaper: Metronidazole, Fluconazole, Ecostat, Hexicon, Flucostat.

Analogs

Manufacturers of pharmacological agents offer analogues that are cheaper than Pimafucin. For example, Flucostat and Diflucan are quite popular agents. What is better to use Pimafucin or Diflucan? The choice of medication should be agreed with the attending physician. For example, if candidiasis occurs in children or during pregnancy, it is safer to use Pimafucin.

The compatibility of Pimafucin with other dosage forms is quite positive; no negative consequences were noted during the study period. Among gynecologists and obstetricians, Pimafucin has positive reviews, high efficiency and dynamics in neutralizing Candida fungal infections in men and women, especially during pregnancy and lactation, as well as in childhood.

Pimafucin for men: application features

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The myth that only women get thrush has long been dispelled. It is now known that both women and men can be prone to candidiasis. Candidal balanoposthitis, or male thrush, is characterized by inflammation of the glans penis and the foreskin around it. The male half of the population is less at risk of developing thrush, because the physiological characteristics of the male genitourinary system prevent the effective reproduction of bacterial microflora.

• Bacteria are washed out of the urethra by urine and further development of infection does not occur.
• Men experience thrush in a milder form, which is why most patients do not immediately notice the disease.
• The appearance of thrush may be an indicator of reduced immunity and the presence of concomitant sexually transmitted infections.
• A fungal infection causes a local inflammation process. Because of this, the damaged organ and surrounding tissue turn red, swell, burning, itching, painful urination and sexual intercourse occur. Later, a whitish coating appears, similar in consistency to cottage cheese, and a lactic acid smell.
• If you suspect candidiasis, you must consult a specialist, undergo an examination, and undergo a course of treatment.

It is better to refrain from self-medication, as this can slow down the healing process several times.

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The most effective method of treating fungal infections is combination therapy, which is based on a powerful antifungal agent. The most effective and common drug is Pimafucin.

Pimafucin for men is a broad-spectrum antifungal antibiotic.

This remedy is prescribed for diseases such as dermatomycosis, candidiasis, balanoposthitis, vulvovaginitis, etc.

• The active ingredient of Pimafucin is natamycin.
• The mechanism of action of the drug is based on the connection with the cell membrane steols and a change in its selectivity.
• The integrity of the membrane is damaged, it ceases to function properly, which leads to the death of the microorganism.

The most sensitive to natamycin are fungi of the genus Candida albicans, which are the causative agents of thrush. Candida is always present in the human body in small quantities. If the balance of microflora is disturbed, this leads to increased reproduction of candida and, consequently, to candidiasis Pimafucin for men is available in suppositories, tablets, cream and ointment.

This variety of release forms allows Pimafucin to be effectively used for the treatment of both women and men. It is most convenient for the stronger sex to use cream.

In the initial stages of candidiasis, preference is given to local treatment with a cream. For prolonged or repeated infections, treatment is usually supplemented with tablets.

Cream and ointment Pimafucin for men

Cream for men Pimafucin 2% is used to treat the outer skin. Available in aluminum tubes of 30 g. The color of the cream can vary from white to light yellow. For quick and easy distribution of the product, the cream contains propylene glycol, cetyl ester wax, decyl oleate, sodium lauryl sulfate, methyl parahydroxybenzoate, propyl parahydroxybenzoate, cetostearyl alcohol.

To combat balanoposthitis, it is necessary to carefully treat the head of the penis with cream up to 4 times a day.

The duration of the course is determined by the attending physician, taking into account the individual characteristics of the patient. The duration of treatment may vary and depends on the form of candidiasis. You should not stop treatment as soon as the symptoms stop bothering you. It is necessary to use the drug on the affected areas for several more days for prevention purposes.

• Pimafucin tablets are used for protracted illness or the occurrence of intestinal candidiasis.
• Since the drug has an exclusively local effect and is not absorbed into the blood, the effect is only on the affected mucous membranes.
• The regimen and dose of the drug are prescribed by the attending physician.
• Take Pimafucin 1 tablet up to 4 times a day, as prescribed by the doctor.
• If the dose is determined correctly and the tablets are taken correctly, then no side effects occur.

The instructions say that a course of treatment with Pimafucin ointment for men is prescribed for at least 7 to 10 days, regardless of the form of the drug. If the patient’s condition does not improve after five days of the course, severe side effects appear, it is necessary to consult a doctor and replace the antibiotic or supplement the treatment with tablets.

Suppositories for thrush Pimafucin analogues of the drug

Suppositories are prescribed for the treatment of vaginitis, vulvitis, vulvovaginitis caused by yeast fungi of the genus Candida.
Only a qualified gynecologist can prescribe the use of suppositories for thrush called “Pimafucin”. Candles should be used once a day, before bedtime. The drug is administered in a lying position. The duration of the course of therapy is a week. After the symptoms disappear, it is recommended to extend treatment for several days. It is not worth carrying out therapy during menstruation, that is, using suppositories for thrush Pimafucin, because the remedy can be washed out through the blood. If the symptoms of the pathology have spread to the mucous membranes of the external genitalia, the use of a cream is prescribed as additional therapy. If Pimafucin suppositories for thrush are ineffective, tablets are prescribed - one tablet four times a day. The course of therapy is three weeks. Men are prescribed the use of the cream.

The duration of the course, dosage, and treatment regimen can only be selected by a doctor. Of course, Pimafucin suppositories for thrush are effective and efficient. But they will only help if used appropriately. Analogues of the tablet form of Pimafucin: Nystatin-Zdorovye - 60 rubles, Alpha Normix - 900 rubles. Analogues of suppositories: Clotrimazole - 60 rubles, Livarol - 360 rubles, Nystatin - 90 rubles.

Pharmacodynamics and pharmacokinetics

The principle of action of the drug is based on the binding of sterols in the cell membrane, violating their integrity, which causes the death of the microorganism. The drug affects yeast-like fungi (especially Candida albicans), yeast, dermatophytes, and pathogenic fungi.

Natamycin is active when used topically, has no systemic effect, and is not absorbed through mucous membranes or skin. The enteric coating of the tablets determines the effect of the drug in the intestines.

Reviews about Pimafucin

Reviews about the Pimafucin series of medicinal antifungal agents are encouraging.

The cream has a beneficial antimycotic effect and gently, without relapse, helps to completely eliminate the symptoms of the disease.

In the first days after use, patients note that the skin becomes less red, dryness disappears, and the affected areas stop itching. The cream is actively used to treat fungal infections in children.

Reviews of the tablets are less optimistic. Some users note a deterioration in health, nausea, and often diarrhea in the first days of taking it. But these minor side effects do not exclude the use of the product for its intended purpose. Patients write on forums about the onset of positive dynamics after the first week of taking the pills.

On the forums, the overwhelming majority of patients report a positive effect after using the medicine. However, there are cases when there is no improvement in the condition or it even worsens. There are also claims about the short-term effect of treatment for thrush and other diseases.

Pifamucin for thrush, according to patients, helps by quickly eliminating its symptoms. Moreover, the cream is effective for both women and men. Pimafucin tablets for thrush also help in the treatment and prevention of candidiasis.

Reviews about the tablets are most often good; patients write about the fast and effective action of the medicine and the complete absence of side effects. Reviews of Pimafucin suppositories for thrush report that they relieve itching faster than when taking tablets, as they act locally. There are no negative reviews about Pimafucin cream; it helps well with fungal diseases and is easily tolerated.

Storage rules and conditions of release from pharmacies

You do not need a doctor's prescription to purchase this thrush medicine.

It is recommended to store the drug at temperatures ranging from +15°C to +25°C. Suppositories should not be kept in the refrigerator.

The shelf life of the drug is 2 years from the date of release (it is indicated on the packaging).

Keep away from children!

Plisov Vladimir, medical observer

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Contraindications

After suppositories, side effects occur very rarely, as they are well tolerated by patients. The only contraindication to their use is intolerance to the main component. In addition, it is not advisable to use this drug in patients under sixteen years of age.

During pregnancy (from the first trimester), Pimafucin suppositories for thrush can be used according to the instructions, since their active substance does not enter the systemic bloodstream and does not systemically affect the body. At the same time, it is necessary to start treatment without prior consultation with a specialist.

During pregnancy, thrush can be treated, but in no case should you do nothing. In infectious processes, there is a high probability of infection of the fetus in utero during development or during its passage through the birth canal.

Please note that during breastfeeding you can use these suppositories for the treatment of fungal pathologies.

Description of the drug

Pimafucin cream is a white product with a yellowish tint with a thick consistency and no characteristic odor. It is intended for the treatment of pathologies caused by yeast-like fungi. These microorganisms belong to opportunistic microflora and do not show themselves for a long time. But with a sharp decrease in immunity, fungi rapidly become more active.

Clinical manifestations of infection include sticking in the corners of the mouth and cheesy discharge from the urethra or vagina. Red spots on the skin indicate a mycotic lesion. All diseases are dangerous, contagious, and require immediate medical intervention. Antifungal drugs are used in therapy, including Pimafucin ointment.

What is the topical application prescribed for:

• mycotic lesions of the skin and mucous membranes;
• fungal infection of the nail plates on the hands and feet;
• bacterial pathologies of the ear, complicated by an associated mycotic infection;
• vaginal candidiasis.

The cream works effectively after the first application to pathological lesions. It helps to quickly get rid of the symptoms of a fungal disease by destroying its pathogens.

When diagnosing an uncomplicated pathology, it is sufficient to use only the cream. When a recurrent disease is detected, other medications are included in the therapeutic regimen. Usually these are tablets of the same name and intravaginal suppositories.

Pimafucin helps well against vaginal candidiasis, but treatment is indicated for both sexual partners. Women are prescribed suppositories or cream, and men only cream.

Clinical and pharmacological group

The cream is an external agent from the clinical-pharmacological group of antimycotic drugs. The active ingredient is a polyene antifungal antibiotic, so Pimafucin can be classified as an antimicrobial agent.

pharmachologic effect

Low concentrations of natamycin have a fungistatic effect.
A polyene antibiotic from the macrolide group inhibits the growth and reproduction of pathogenic fungi. This property is often used for prophylactic purposes to prevent the spread of infection. Natamycin in high concentration exhibits powerful fungicidal activity. It prevents fungi from producing ergosterols, the structural elements of membranes. As a result, the integrity of the entire cell is disrupted, so it quickly collapses.

Pimafucin is a broad-spectrum antimycotic agent. It is active against the following fungal species:

• yeast-like fungi Candida - causative agents of oral candidiasis and thrush;
• dermatophytes that cause severe skin lesions.

Pimafucin is one of the few antimycotics that are used throughout treatment. The fact is that fungi are not capable of developing resistance to natamycin.

Release form and composition

The Pimafucin therapeutic line includes three of its dosage forms. This is a cream for application to the skin and mucous membranes, vaginal suppositories and tablets for oral administration. All drugs contain one active substance with pronounced antifungal activity - natamycin.

The Italian manufacturer packages the cream in a plastic or aluminum tube of 30 g. The secondary packaging for the drug is a yellow cardboard box with attached instructions for use.

In addition to natamycin, Pimafucin cream contains the following auxiliary components:

• macrogol;
• cetostearyl alcohol;
• sodium lauryl sulfate;
• distilled water;
• methylparaben;
• propylparaben;
• wax.

Additional ingredients ensure maximum absorption of the antibiotic into the mucous membranes and skin.

Many of them have weak antiseptic properties, which enhances the therapeutic effect of the drug. The components of the product form protective shells, preventing bacterial infection of tissues affected by inflammation.

Storage conditions and periods

The shelf life of the antimycotic drug is 24 months, after the seal of the tube is broken - 3-4 weeks. It should be stored at room temperature in a dark place out of reach of small children. Freezing Pimafucin cream is not allowed. If the consistency, color changes, or a rancid odor appears, the product is not suitable for treatment.

Side effects and contraindications

Pimafucin, having a wide spectrum of action against fungi and some types of bacteria, has a minimum of contraindications. Regardless of the form of the drug, it cannot be used if you are hypersensitive to the components. In addition, the tablets are contraindicated under the age of 3 years. During treatment you should not drink alcohol.

An overdose of Pimafucin, even when taken internally, is impossible, since it has extremely low absorption. The list of side effects is also small. The drug is generally well tolerated by all patients. In some cases there are

• slight nausea and diarrhea when taking pills - appear at the beginning of the course and go away on their own;
• mild irritation of the skin and mucous membranes, burning sensation - when using the drug topically.

All side effects pass quickly and do not require discontinuation of the medication. The only reason to refuse Pimafucin is its intolerance. If side effects occur, you should consult your doctor again - reduce the dose or discontinue the drug.

Mechanism of drug action

The active ingredient Pimafucin blocks sterols, the main active elements of the fungal wall. This leads to disruption of their function of exchanging nutrients with the external environment. The integrity of the pathogen cells is disrupted, and the microorganisms quickly die.

When Natamycin is applied to the skin and mucous membranes, the drug penetrates well into the inner layers, affecting all parts of the fungal colony, but is not absorbed into the blood vessels. Therefore, the medicine does not affect the liver and kidneys.

When taking the tablet form of Pimafucin, its active substance is 85–90% excreted from the intestines with feces - absorption into the systemic circulation is minimal.

There is no data on the resistance of fungal infections to the drug in clinical use. The drug always gives high results in the treatment of candidiasis. It can be used for relapses of the disease an unlimited number of times, taking a break for 2-3 weeks.

Results of a laboratory study of the patient’s biological material before (left) and after (right) use of Pimafucin. Visible result of fungus suppression

Instructions for use of Pimafucin cream/ointment for women with thrush

Not the most popular form, however, the most effective and has no contraindications based on gender and age (except for children under 1 year).

Its composition is allergen-neutral, and in addition to natamycin (the concentration per 1 g of product is only 20 mg), it contains propylene glycol (responsible for consistency and easy application to the skin), cetosteoryl alcohol (necessary to increase absorption) and purified water as a base and skin protection from a chemical burn.

Apply to clean and moisturized skin, but do not rub in, but simply cover with a cotton cloth and, if necessary, secure with a bandage. Traditionally, they bandage twice a day, but there is no regulation on the amount (according to doctors’ recommendations, the layer should be no more than 1.5 mm).

Pimafucin ointment and cream for men: Instructions, composition, how to apply

The suppository contains natamycin as an active ingredient. Additional components include: cetyl alcohol, adipic acid, solid fat, sorbitan trioleate, polysorbate 80, sodium bicarbonate.

Pifamucin ointment. The main component is natamycin. Auxiliary components: propylene glycol, cetostearic alcohol, sodium lauryl sulfate, purified water, decyl letate, methyl parahydroxybenzoate, cetyl wax ether, propyl parahydroxybenzoate.

Pifamucin tablets. The active ingredient in the tablets is natamycin, auxiliary ingredients: kaolin, white beeswax, polyvinylpyrrolidone, titanium dioxide, sucrose, magnesium stearate, kaolin, methyl parahydroxybenzoate, gelatin, gum arabic, potato starch, calcium carbonate, lactose, triacetin.

The drug is available in three forms: tablets, cream and vaginal suppositories for thrush. White round tablets are available in dark glass bottles of 20 pcs. The cream has a white or light yellow color, is produced in aluminum or plastic tubes of 30 g. Suppositories are produced in foil strips, which contain 3 suppositories; the package can contain 1 or 2 strips.

Pimafucin ointment or cream for men against thrush has long established itself on the market as a proven and effective remedy. It should also be noted that in the entire history of use of this antibiotic, not a single case of resistance has been observed. The drug has a local effect and is not absorbed through the walls of the gastric tract, which makes it possible to have a direct effect on the site of infection.

Pimafucin in the form of a solution is used quite rarely, however, this format of the drug is best suited for treatment if thrush affects the oral cavity. The medicine must be used at least 2 times a day, holding it in the mouth and rinsing for 7-8 minutes. There is no need to swallow the drug.

When giving preference to Pimafucin, trying to eliminate a fungal disease in the body, it is also necessary to take into account that this drug can be used as a prophylactic drug against thrush. Which is another plus in the collection of benefits of this product. By performing timely treatment, based on the doctor’s recommendations and instructions for use, you can easily overcome the painful condition with the help of Pimafucin, without resorting to additional medications.

The list of contraindications is quite small - hypersensitivity to the substances of the drug. Allergic reactions to the substance nitamycin are quite rare. There are no serious side effects when using the drug. At the beginning of therapy, minor digestive disorders (when there are gastrointestinal diseases) and nausea may occur; these symptoms disappear on their own in a short time and do not require treatment. While using the cream, a burning sensation may occur, but this is not a reason to complete the course.

The price of the drug is in the range of 60-450 rubles. The cost depends on the region, manufacturer and form of release. You need to find out the exact cost at the pharmacy.

Most men, when fighting thrush, use Pimafucin cream (ointment) as a reliable and proven antimycotic agent. Some people are attracted by the fact that the treatment time does not last long, and the treatment effect is noticeable almost immediately. Some people trust the manufacturer - Pimafucin is produced by the largest companies and has long been one of the most popular drugs on the pharmaceutical market.

The manufacturer envisages the release of three main forms of the drug: cream, tablets, vaginal suppositories.

Treatment of foot and nail fungus is carried out with the antibiotic Pimafucin externally with cream and orally with tablets, or systemically, combining them. The active ingredient, natamycin, is a broad-spectrum antibiotic.

Additional active ingredients vary depending on the release form.

What and how to take for thrush?

What to take for thrush to prevent the disease from returning? One drug is not enough, it is necessary to eliminate the cause of the disease, increase immunity and normalize the microflora in the body.

Candidiasis is a common disease in gynecology. If the disease is not treated, it can develop into a chronic form and serious complications may arise. Thrush is not a sexually transmitted disease, but can be transmitted sexually. As Candida fungi multiply, they affect the genitals, skin, and oral mucosa.

Signs of illness

Candidiasis can develop in girls, children and men who have not given birth, and more often appears in women of childbearing age. There are many reasons for the proliferation of fungal infections. This disease causes discomfort, spoils sex life, and negatively affects everyday life.

To identify thrush, you need to know the symptoms of the disease:

• Itching, burning in the genitals, the mucous membrane becomes inflamed, causing discomfort, which intensifies after washing or urinating. It is necessary to dry the organs to reduce these symptoms.
• Painful sensations after sexual intercourse bring discomfort. Ulcers form in the affected area, causing severe pain.
• Inflammation and swelling of the genital organs.
• Vaginal discharge appears, similar to a curd mass, when the fungus multiplies greatly.
• A rash may appear, bubbles with liquid, when they burst, ulcers and erosions form. This causes pain.
• Deterioration of health. Discomfort causes irritation, nervousness, and insomnia. At night, the symptoms intensify, and the itching also increases after a long walk, during menstruation.
• Thrush can affect other organs. If the infection spreads to the bladder, urination becomes more frequent and your body temperature may rise.

If you have such signs, you should consult a doctor for help and not self-medicate.

Causes of the disease

The main reason for the proliferation of fungi is a decrease in the immune system and disturbances in the vaginal microflora. This Candida fungus is present in every body; with reduced immunity, it begins to multiply.

There are many factors that contribute to the development of candidiasis:

• Infectious diseases cause a decrease in the body's defense against fungal infection.
• Hormonal disorders are more common during pregnancy, before menstruation.
• Use of oral contraception.
• Long-term use of antibiotics.
• Disorders of the intestinal microflora, in which bacteria can enter the genital area.
• Climate change, adaptation to water.
• Use of scented products and panty liners for hygiene purposes. They can cause an allergic reaction by damaging the mucous membrane.
• Poor nutrition, excessive consumption of sweets, baking with yeast.
• Vitamin deficiency adversely affects the skin and mucous membranes.
• Excess weight.
• Physical fatigue.
• Regular stressful situations.
• Diabetes.

All these factors can adversely affect the condition of the body, which leads to the proliferation of fungal infections. In the absence of proper treatment, thrush can spread, affecting other organs, which leads to serious problems.

Therefore, if you have symptoms of candidiasis, it is better to consult a gynecologist, who, after examination, will prescribe drug therapy.

Diagnosis and drug treatment of candidiasis

When examined in a gynecological chair, the doctor will be able to make a preliminary diagnosis. A vaginal smear will help determine the presence of harmful bacteria and their composition. Microscopic examination will help identify Candida fungus and the number of immune cells.

Sometimes it is recommended to inoculate a microflora nutrient medium, which determines the type of fungus and its reaction to certain medications. These studies will help you choose the right treatment for thrush and prevent relapse.

For candidiasis, antifungal medications are prescribed; they are divided into two groups: local and systemic.

Systemic medications are taken orally, most often in tablets or capsules. Active substances are absorbed into the blood and affect the entire body. The disadvantage is that there are many side effects and increased toxicity. Such products are not recommended for pregnant women to drink or when feeding their baby with breast milk. Systemic medications are recommended for the chronic form of the disease, when candidiasis occurs more often than four times a year.

All tablets should be taken after consultation with your doctor to prevent serious consequences.

To get rid of thrush, it is important to determine the cause of the disease; the doctor must:

• Determine the sensitivity of the fungal pathogen to an antifungal agent.
• Eliminate disturbances in microflora, normalize acidity, balance of beneficial bacteria.
• Boost the immune system, then the body will help fight infection.
• Normalize the hormonal system in the body.

When treating thrush, the patient must abstain from sexual relations, alcohol, taking antibiotics, and cancel birth control.

What effective medications should be taken for vaginal candidiasis? This question worries many women who are faced with the problem of fungus. Tablets are a common method of treatment, because they are easy to use and do not require time. They relieve symptoms of the disease in a few days and get rid of infection in all organs.

In modern medicine, the most effective are:

• Fluconazole, it is enough to drink 150 milligrams of the drug if the disease is mild.
• Ketoconazole should be taken 1-2 tablets per day, for a course of 5 days.
• Natamycin, drink one piece at a time, for at least three days, depending on the severity of the disease
• Miconazole, drink in the morning, for three days.
• Nystatin take four tablets per day, the course of treatment is about ten days.

All drugs are not recommended for use by pregnant women, or without a doctor’s prescription. To achieve results, it is important for both partners to undergo a course of comprehensive treatment until complete recovery.

Pimafucin during pregnancy and lactation

On the contrary, the use of tablets once a day, one capsule in the first trimester of pregnancy, reduced the risk of premature termination of pregnancy, increased the tone of the uterus, and prevented the proliferation of fungal parasites in vaginal candidiasis and foot fungus.

In addition, experts noted the absence of a negative effect of the active components of Pimafucin on the fetus, as well as the absence of toxic manifestations of all forms of the drug.

Under the influence of body temperature, vaginal suppositories quickly dissolve, forming a foamy mass, due to which the active substance is distributed evenly. For recurrent or chronic infections, therapy can be supplemented with cream or tablets.

Cetyl alcohol, which is part of the suppositories, can cause a burning sensation in the genital area. Candle therapy should be interrupted during menstruation. During treatment with suppositories, sexual intercourse may not be excluded. However, both partners should be examined, and if a lesion is detected, Pimafucin cream for men should be used. Treatment with ointment for men occurs in the manner prescribed by the instructions. When having sexual intercourse during treatment, barrier contraceptives should be used.

It is possible to prescribe Pimafucin to newborns.

There are no contraindications for taking the drug for pregnant women or while breastfeeding. Tablets, creams and suppositories are used for thrush both in the early stages of pregnancy and in later stages. Most often, Pimafucin suppositories are prescribed during pregnancy, rather than other forms of this medicine. The drug is non-toxic and safe for the fetus both during the 1st trimester and 2nd trimester, as well as during lactation. However, to minimize the risk, it is better to take suppositories during lactation, or cream. Use of the drug is as indicated in the instructions.

Indications for use of the cream

Pimafucin is prescribed for the treatment of ailments associated with fungal pathogens. The drug is effective for all types of candidiasis. Candidiasis is a fungal infection that can affect both the external skin and internal mucous membranes.

Intestinal candidiasis is treated with tablets. For the treatment of vulvovaginal candidiasis in women, suppositories should be used. The drug in the form of a cream is indicated for use in the treatment of thrush, fungal infections of the skin and nails.

Pimafucin is considered the best treatment for thrush in both women and men. Thrush manifests itself with itching and a burning sensation, white cheesy discharge in women.

Women are most often prescribed this drug in the form of suppositories. External mucosal lesions can be treated with cream. Some reviews from patients who have gotten rid of this disease contain information that pimafucin for thrush is the most effective remedy among similar medications.

Thrush is diagnosed much less frequently in men than in women. The development of thrush in men is influenced by the state of immunity. With a normal protective function, the risk of developing thrush symptoms in men is minimal.

To treat thrush in men, ointment should be used. It should be applied to the affected areas in a thin layer. The course of treatment is determined by the doctor. On average, thrush in men is treated for about a week.

All necessary information regarding the use of the drug is contained in the instructions supplied with it.

Forms of release of the drug

To ensure that the treatment of candidiasis is as fast as possible and gives a good result, the optimally suitable form is chosen among natamycin preparations:

• enteric tablets;
• ointment;
• vaginal suppositories.

Pills

Each tablet contains 100 mg of natamycin. Excipients are beeswax, kaolin, dye (titanium dioxide), sucrose, polyvidone and stearic acid. These components are necessary only to formulate the tablets and are not active substances. The medicine is available in bottles of 20 tablets each.

The tablets should be used for intestinal candidiasis, for adults – 4 times a day for a week. For children, the medicine is allowed from 3 years of age. Drink it twice a day for 7 days.

Ointment

In this form, the drug is released in tubes of 30 grams. Natamycin in the cream is 2%, the remaining 98% comes from auxiliary components. These are fatty alcohols (cetyl and stearic), distilled water, cetyl ether, surfactant sodium lauryl sulfate, methyl para-hydroxybenzoic acid, preservative E1520.

The cream is economical to use, has a neutral odor, is quickly absorbed, and does not require rinsing. Treatment is indicated for genital candidiasis, including balanoposthitis.