Most vaginal capsules and tablets are not recommended for use during menstruation. The use of Polygynax during menstruation is allowed, but the woman must administer the product correctly, following the instructions. Find out how to use the medication correctly, as well as the main advantages of such therapy during menstrual periods.
Composition of the drug
The drug has three active components:
- Neomycin sulfate.
- Polymyxin sulfate.
- Nystatin.
The first two substances represent a group of antibiotics that are effective in eliminating gram-positive and gram-negative bacteria. The exceptions are streptococci and anaerobic microorganisms. Nystatin in Polygynax helps with thrush by acting on Candida fungi.
The drug has the following effects on the body:
- antibacterial effect;
- antifungal effect;
- improvement of metabolic processes in the vaginal mucosa.
Among the advantages of the drug it is worth highlighting:
- uniform distribution of components;
- virtual absence of absorption of substances into the systemic circulation;
- active effect on many pathogens.
Mechanism of action
Polygynax is a highly effective remedy in the fight against yeast-like fungi of the genus Candida because it combines a number of effective components at once.
It is based on the antibiotic substances polymyxin and neomycin, which prevent the proliferation of pathogenic microorganisms and their normal functioning.
As a result, the mucous membranes of the vagina return to their normal state. Additional elements included in Polygynax are:
- Nystatin, which disrupts the metabolic processes of candida parasites in the female body;
- Dimethylpolysiloxane gel, which envelops the surface of the genitals, eliminates itching and improves the nutrition of tissue structures;
- Water;
- Hydrogenated soybean oil;
- Gelatin;
- Glycine;
- Typhosis 63;
Despite the wide range of effects on fungi, Polygynax does not have a negative effect on the natural vaginal microflora. It is practically not absorbed into the mucous membranes and is evenly distributed over the affected areas after the capsule dissolves.
Indications
Gynecologists prescribe to patients the use of Polygynax suppositories during menstruation for infectious and inflammatory diseases that were provoked by microorganisms sensitive to the drug. This includes:
- inflammation of the vagina with nonspecific symptoms;
- fungal colpitis;
- vaginitis of mixed form;
- simultaneous inflammation of the vulva and vaginal mucosa;
- candidal colpitis (thrush);
- inflammatory disease of the cervix.
It is advisable for any woman to take a smear before treatment to exclude the presence of microorganisms resistant to the active components of the drug. Otherwise, the treatment will not have the desired effect, and the disease may become chronic.
Active substance
Composition of capsules
Both forms of Polygynax have a combined composition. There are 3 types of antibiotics as active components.
- Neomycin. A broad-spectrum antibiotic from the aminoglycoside group, active against gram-positive and negative bacteria, kills E. coli, Proteus, staphylococcus, mycobacterium tuberculosis, enterococcus and other microorganisms.
- Polymyxin B sulfate. A polypeptide antibiotic, active against gram-negative microflora, kills Escherichia coli, Klebsiella, Salmonella, Eterobacter, etc., and is effective against all forms of microbes (including “dormant” and those in the growth phase).
- Nystatin. An antibiotic from the polyene group, it is especially effective against the causative agent of candidiasis, and is also active against other fungi (blastomycetes, aspergillus, causative agent of coccyoidosis).
Polygynax during menstruation
It is not uncommon for severe symptoms of thrush to occur during menstruation, as well as the manifestation of the disease on any day of the cycle. Doctors do not recommend interrupting therapy for infectious and inflammatory diseases. Therefore, you can be treated with Polygynax during menstruation, and this is the rule, not an acceptable exception. Unlike other vaginal suppositories, the drug does not lose its effectiveness due to monthly bleeding.
The advisability of therapy during menstruation is justified by the following factors:
- During endometrial rejection, optimal conditions are created for the proliferation of pathogens.
- The risk of movement of infections and bacteria from the vagina to other genital organs (uterus, ovaries) increases.
- Menstrual flow can aggravate hidden inflammatory processes that previously did not manifest themselves.
- Critical days are the best period to eliminate problems with the vaginal microflora.
- The effect of the drug is not enhanced, but menstruation helps solve problems with infections in a comprehensive manner.
- Interrupting the course may result in incomplete or completely ineffective treatment.
Thanks to all these reasons, taking Polygynax during menstruation is an excellent method of combating many sexually transmitted infections.
If the patient refuses the procedures, then there is a possibility that the symptoms of the disease will intensify and move to a more advanced stage.
Contraindications to Polygynax
At the very beginning of pregnancy, the use of the drug is not recommended because its effect on the developing fetus has not been studied. When the placental barrier is formed (after 14 weeks), taking the drug becomes possible.
Nursing mothers should not use the medicine because antibiotics may pass into breast milk. They can have a bad effect on the developing intestinal microflora of the child.
Otherwise, the drug acts mildly and where other remedies for thrush cannot be used, it can be used.
Duration of treatment
The drug Polygynax is produced by the manufacturer in several versions, which differ in the number of suppositories in the package:
- 6 pcs.
- 12 pcs.
For prevention, it is enough to buy a package of six vaginal capsules, which will last for the corresponding number of days. The standard course of treatment involves 12 procedures (one suppository once a day). Sometimes the duration of therapy increases to two weeks, but after resolving this issue with the doctor.
If the patient has missed one or more injections of Polygynax, then an increase in the daily dose is not required. It is enough to continue to use the drug in the usual amount until the end of therapy.
Who uses this drug and how?
Polygynax for thrush is used as one of the options for mandatory course therapy. In most cases, even severe fungal manifestations disappear already on the 3rd day after the start of treatment.
Note!
If you have started introducing capsules into your body, you cannot stop doing this without special instructions from your doctor, otherwise the effect of Polygynax will not only disappear, but will also add to health problems. If you miss just one day, therapy should be resumed the next day, without compensating for the “lost” procedure.
Lack of systematic use of Polygynax can lead to the development of chronic candidiasis with regular relapses of the disease. Fungi will gradually develop “immunity” to the components that form the drug, and therefore it will be much more difficult to get rid of them.
At the same time, despite the fact that Polygynax is considered an antibiotic, there are no exact regulations regarding the daily time of its introduction into the body.
In addition to vaginal candidiasis, doctors also prescribe these suppositories to those patients who have been diagnosed with bacterial vaginitis, cervical erosion, fungal or bacterial cervicitis and nonspecific types of vaginitis.
Polygynax is available in the form of an emulsion and in the form of vaginal capsules, which are more popular among patients. The drug is not intended for men. There is a special product for children - Polygynax Virgo.
How to use?
It is important not only to insert the vaginal suppository on time, but also to insert it correctly. Therefore, a woman should follow the following recommendations if she uses Polygynax during menstruation:
- The duration of therapy should not exceed 12 days, otherwise pathogenic microorganisms become resistant to the active components.
- It is better to use the product in the evening just before bed. If possible, capsules should be inserted in a supine position.
- It is worth cleaning the vagina and hands with warm water without using gel, soap or other intimate hygiene products.
- The ideal depth at which the suppository is applied is the length of the index finger.
- If you place the capsule incorrectly, there is a risk of substances leaking out along with blood and daily secretions.
- It is better to avoid tampons, giving preference to hypoallergenic, odorless pads. Even with optimal administration of the product, some components leave the vagina.
- It is advisable to abandon latex caps and condoms, which cause undesirable effects on the mucous membrane, until the end of the course.
Cost by release form
Vaginal capsules Polygynax
Polygynax are special capsules for intravaginal use. They have a round shape and a smooth surface. The color of the capsule shell is beige or pale yellow. Inside contains a medicinal emulsion - a mixture of soybean oil, stabilizers and active ingredients.
Candles are produced in contour cells of 6 pieces. There are 2 packaging options - with one or two contour cells inside. Accordingly, you can purchase 6 or 12 candles. Each package comes with instructions. There is no applicator for administering capsules.
Another form of release is Polygynax Virgo. Emulsion capsules have the shape of an oval tube without a gelatin shell. The form is intended for introducing the emulsion into the vagina. Designed for girls and teenagers for whom the use of candles is inappropriate.
Prices for Polygynax differ in different pharmacies, which depends on the marketing policy. A large package (12 capsules) can be purchased for 620-720 rubles. A package for a preventive course (6 capsules) costs 350-450 rubles. The children's form of Polygynax Virgo (6 capsules) costs 490-570 rubles.
Is there a possibility of a delay?
Among the side effects there are no indications of possible cycle disruption. But the use of any antibiotics can affect menstruation and women’s health in the following ways:
- longer (over 35 days) interval between menstruation;
- shortening of the monthly cycle;
- long periods;
- very little or too much blood loss.
Most often, women experience not a delay, but a shift in the onset of regulation. Also, the absence of monthly bleeding may be due to pathogens that the woman is trying to eliminate with Polygynax suppositories.
The effectiveness of using vaginal suppositories, capsules and tablets largely depends on the woman herself. During menstruation, Polygynax does not provoke increased side effects, which occur only with improper use, increased dosage, or individual intolerance. Therefore, the regulations do not act as a contraindication to continued therapy and do not reduce the effect of the active substances.
Is it worth looking for analogues of Polygynax?
There are no complete analogues of the drug today, unless we consider Polygynax Virgo as a separate drug. You can take this drug if regular Polygynax is not available in the pharmacy. There is no need to specifically look for analogues like nystatin, because this drug does not have a complex effect and has a greater number of side effects.
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Pharmacokinetics
According to reviews, Polygynax is distributed evenly on the vaginal mucosa, providing local fungicidal and bactericidal effects in this area. However, it is almost not absorbed from the surface of the vaginal mucosa.
In what cases is the product used?
If a patient exhibits symptoms of various kinds of infectious and inflammatory pathologies in the intimate areas, which were provoked by microorganisms of various origins, then it is quite difficult to do without a local antibiotic. The drug is recommended for use if:
- nonspecific vaginitis;
- fungal vaginitis;
- vulvitis;
- cervicovaginitis;
- vulvovaginitis.
In addition, according to reviews, Polygynax candles can be used in the following cases:
- Prevention of various pathologies of the genital organs caused by inflammation or infections.
- In advance before diathermocoagulation of the uterine cervix and after this procedure.
- A preventive measure before surgical intervention in the patient’s intimate area.
- Preparation for examination of the intrauterine space.
- Prevention before childbirth.
- Sanitation of abortions and birth canals. This is confirmed by patient reviews about Polygynax.
Features of the drug
Polygynax is an effective and fast-acting drug that is among the affordable drugs in the price category.
Polygynax packaging
Its cost in pharmacies is approximately 400 rubles per package. It is noted that this remedy successfully treats not only various forms of thrush, but is also able to cope with other gynecological diseases that arise independently or against the background of chronic candidiasis. At the same time, suppositories of this brand are among the antibiotics, due to which the instructions should be carefully studied before the first use, and it is also important to remember all the advice of the attending physician.
Polygynax is used for thrush as a mandatory course of treatment.
Severe symptoms of fungal pathology usually disappear completely on the third day after the first introduction of the capsule into the body. However, it is impossible to interrupt the started therapy unless there are serious instructions for such an action. Despite the fact that the medicine is classified as an antibiotic, there are no separate requirements that the drug should be administered strictly at the same time. Also, in case of missing a day, treatment should continue without compensation for the “lost day,” but it is recommended that in such circumstances, consult a gynecologist for possible correction of the treatment plan.
The main active substances in this drug are:
Excipients:
- glycerol;
- water;
- gelatin;
- soybean oil (hydrogenated);
- typhoid 63.
Suppositories have antibacterial and antifungal effects on the body. Due to this, Polygynax is used not only to correct the condition of thrush, but also in the context of such gynecological diseases as cervical erosion, bacterial vaginitis, cervicitis (bacterial and fungal), and nonspecific forms of vaginitis. The components of the drug quickly block the growth of pathogenic organisms and destroy existing negative microflora. In addition, suppositories successfully cope with itching, unpleasant vaginal discharge, swelling and irritation of the mucous membranes.
Polygynax has almost no side effects
Unlike many other “strong” drugs, Polygynax has virtually no side effects or contraindications, and no cases of overdose with accompanying symptoms have been registered.
Thus, the remedy requires proper administration so that the instructions are followed, only for the reason that, otherwise, the therapy may not bring the desired result. It is noted that when the course is interrupted or medicinal capsules are unsystematically administered, thrush goes into a chronic stage with frequent relapses, and the yeast-like fungus gradually develops “immunity” to the main components of the medicinal drug. Due to this, further treatment with nystatin-based drugs may be completely ineffective.
Minimal contraindications include:
- individual intolerance and allergy to the composition of Polygynax;
- early stages of pregnancy (first trimester), suppositories should be used with caution in the 2nd and 3rd trimesters;
- renal failure; excessive use of the drug can worsen the well-being of such patients;
- breastfeeding period.
No alcohol during treatment.
You can use this medicine at the time of menstruation. But you will have to abstain from drinking alcohol throughout the entire course of treatment. Sexual intercourse with a regular partner, who must also undergo therapy against candidiasis, is not encouraged and is permissible only with the consent of the attending physician.
Possible side effects:
- allergic reaction (itching, skin rashes, swelling of the mucous membranes, drug-induced urticaria).
During therapy, many women note the presence of copious translucent vaginal discharge in the morning. This is not a pathological reaction or side effect. Therapy should not be interrupted.
Polygynax is available in two forms: vaginal capsules and emulsion.
Packages of capsules can be of two types: for 6 pieces and for 12. The color of the candles is milky in color, small in size, quite elastic, oval in shape.
Polygynax Virgo
The use of the drug Polygynax for men is prohibited. A separate form of the drug is available for children called “Polygynax Virgo”.
These suppositories are also prescribed as prophylaxis, before abortions and other surgical interventions.
Price category
The affordable cost of the drug is a significant advantage for many women suffering from vaginal candidiasis. A package with 6 capsules can be purchased for an average of 350 rubles, and with 12 capsules - for 550 rubles.
What is the cost of this drug in your pharmacies? ???
The drug "Polygynax" is used quite often for thrush, as it helps to get rid of unpleasant symptoms quite quickly and effectively. In just a few days, this remedy will help eliminate the unpleasant consequences of bacterial vaginosis.
The active components of Polygynax not only suppress pathogens, but also prevent the infection from occurring again in a woman.
Side effects
Polygynax suppositories for thrush are easily tolerated. Side effects occur quite rarely and are often associated with the likelihood of a local allergy to the drug. In this case, symptoms such as:
- redness;
- rash in the genital area;
- swelling;
- burning sensation.
If the dosage is exceeded, as well as the duration of use of the drug, systemic side effects may occur, especially in women suffering from renal failure. This is explained by the effect of aminoglycosides on the body, which manifests itself in hearing loss, as well as impaired renal function. However, such complications are quite rare. If they occur, you should definitely seek help from a doctor.
Suppositories as a dosage form
Suppositories (suppositories) are considered one of the dosage forms of medications and consist of a base (which gives the shape of a candle) and a medicinal substance. A characteristic feature of suppositories is their ability to remain solid at room temperature and melt to a liquid state at body temperature. According to the method of administration, suppositories are divided into 3 groups:
- rectal - inserted through the anus into the rectum and can be shaped like a cigar, cone or pointed cylinder;
- vaginal - inserted into the vagina and come in the form of balls, egg-shaped or cone-shaped;
- sticks - are inserted into the cervix, ureter, external auditory canal, and so on.
The advantage of suppositories is that the drug enters the blood quickly (after 30 minutes about 50%, after 1 hour - 100%), bypassing the digestive tract, without being destroyed in the liver. In addition, suppositories that are administered vaginally, in addition to their generalized effect, have a local effect on the site of damage. When using suppositories, there are practically no allergic reactions, and the administration of suppositories itself is quite simple and painless.
In the treatment of ESM, several groups of vaginal medications are used, each of which has its own therapeutic effect:
- anti-inflammatory drugs;
- antibacterial;
- birth control contraceptives;
- antiseptic.
Against cervical erosion, only one group of suppositories or several medications with different spectrum of action can be used at once.
Directions for use and dosage
Suppositories for thrush Polygynax require deep intravaginal administration. Place suppositories daily, once a day, lying on your back. It is more convenient to do this before bed, since under the influence of heat the shell and contents of the candle become liquid. The duration of the course is determined by the gynecologist, it depends on the diagnosis and severity of the infection. Typically it lasts 6-12 days. If a day of treatment is missed, the next injection of the capsule is performed without any problems the next evening.
Vaginal administration of capsules
Capsules are inserted into the vagina before bedtime. A single application per day is sufficient for both prevention and treatment. Depending on the purpose of use, the duration of the course differs. For the treatment of gynecological diseases, Polygynax capsules are prescribed for 12 days, for preoperative sanitation of the vagina - for 6 days.
Polygynax Virgo
The medicine is used after evening toilet. It is better to administer the suppositories immediately before going to bed so that the medicine does not leak out during movements. One capsule is removed from the contour cell, inserted into the vagina, and pushed as deep as possible with a finger. Polygynax Virgo is used slightly differently.
Some of the drug may leak out during sleep. Care should be taken to protect underwear and bed linen.
During therapy, a woman should remember some rules:
- you cannot use tampons;
- you can’t douche;
- you should wear cotton underwear;
- it is better to abstain from sexual intercourse;
- You should wash only with your own washcloth;
- Dry yourself exclusively with your own towel.
Both forms of the drug can block the effect of spermicidal drugs and disrupt the density of latex. Even protected sex during treatment does not exclude the possibility of pregnancy.
Side effects from using Polygynax
Like any other medicine, Polygynax may cause side effects.
READ MORE: How to properly treat thrush (candidiasis) in men
Possible side effects include allergies in the form of swelling of the mucous membranes, itching, skin irritation, and drug-induced urticaria.
Long-term use of the drug may lead to an increase in the intensity of side effects. As soon as a woman notices at least one unpleasant symptom, the use of suppositories should be stopped and the attending physician should be told about it.