What is more effective for the treatment of endometriosis - Janine or Yarina?

Instructions for use of the drug Yarina

Yarina is a monophasic oral contraceptive with pronounced antiandrogenic properties. In its chemical composition, the drug combines two active substances: ethinyl estradiol and drospirenone. Being a low-dose contraceptive, the drug, first of all, inhibits the ovulation process by changing the viscosity of mucus on the cervix. Due to these processes, fertilization becomes impossible.

Being a complex drug, Yarina combines the properties of two active ingredients.

In turn, drospirenone has anti-MKS activity, which prevents fluid retention in the body . In combination with ethinyl estradiol, the substance improves the lipid profile , thereby regulating the concentration of HDL. In addition, the combination of two components gives a pronounced anti-acne effect, reducing the secretion of the sebaceous glands. Drospirenone, having an affinity for natural progesterone, has neither androgenic nor estrogenic activity , which significantly reduces the number and frequency of side effects. Like all monophasic hormonal contraceptives, Yarina has a positive effect on the woman’s body . The menstrual cycle improves , and bleeding is more easily tolerated and its duration is shortened, which significantly reduces the risk of developing anemia. The pain of menstruation decreases or disappears altogether.

against endometriosis

The multicomponent drug is a low-dose monophasic contraceptive of modern development. Its action is provided by two active substances - ethinyl estradiol and drospirenone.

Pregnancy prevention is achieved through several processes at once. During Yarina's course, ovulation is suppressed and at the same time the structure of cervical secretion changes. It becomes so thick and viscous that sperm cannot penetrate the uterine cavity. In addition, the contraceptive suppresses the growth of the endometrium, which is necessary for the complete attachment of a fertilized egg.

Drospirenone, in turn, has an antimineralkorticoid effect: it prevents weight gain and fluid accumulation in the body, which helps prevent swelling. Thus, Yarina not only protects against unwanted conception, but also relieves symptoms of PMS.

Unlike many other similar drugs, the contraceptive, thanks to the drospirenone it contains, has a beneficial effect on appearance. Since the substance is characterized by antiandrogenic activity, as a result of its action, the activity of the sebaceous glands decreases, acne disappears or is significantly reduced. This is explained by the fact that drospirenone has an effect similar to endogenous progesterone, which is synthesized by the ovaries.

For therapeutic purposes, Yarina is used to normalize the menstrual cycle, namely, to reduce its duration and intensity of bleeding. Also indicated are chronic hemorrhagic anemia and pain during menstruation. All these disorders are also characteristic signs of endometriosis.

Effect of Yarina on endometriosis

The contraceptive is one of the most effective among combined contraceptive drugs used in the treatment of endometriosis:

• Blocks the pituitary gland's synthesis of gonadotropes and their release
• Suppresses the production of sex hormones by the ovaries
• Neutralizes proliferative changes in the endometrium

Thanks to the effects produced, cyclical processes in the endometrium stop, and with a long course, atrophy begins. As a result, the functioning of endometriotic lesions is suppressed.

How to take Yarin tablets for endometriosis

The contraceptive package contains 21 tablets, designed for one course of hormonal treatment. To prevent pregnancy, the pills are taken daily, one at a time, starting on the first day of menstruation. After a woman takes 21 tablets, she must take a week-long break, during which a discharge similar to menstruation begins. After the end of the time interval, taking the tablets is resumed.

If for some reason a woman was unable to take the pill, then it should be taken at the first opportunity. If the time since the last dose is more than half a day, the woman is recommended to take additional protection for a week.

With this scheme of use, the growth and then separation of the endometrium during menstruation is suppressed, the possibility of blood flow into the pelvis is blocked, and the processes of regression of endometrioid lesions are started.

The duration of Yarina's course in the treatment of pathology depends in each case on the severity of endometriosis and the patient's indications. But the maximum course duration is 6 months. It cannot be exceeded. If after its completion there is a relapse of the disease, then the possibility of re-treatment with the same contraceptive should be determined by the gynecologist.

Possible unwanted effects:

Most often, women complain of headaches and discomfort in the chest (pain and swelling), but there are other side effects of Yarina, which manifest themselves in the form of:

• Frequent mood swings, depression
• Decreased sexual desire
• Nausea
• Migraine
• Thromboembolism of veins and arteries
• Bleeding.

Main indications for taking Yarina

As can be understood from the description of the drug, in most cases Yarina is used as a hormonal contraceptive . In addition, the following indications can be noted:

• Cosmetic regulation of sex hormones. As a result of the correction of the production of androgenic hormones, the activity of sebum production decreases, which leads to a decrease in the manifestation of skin diseases such as seborrhea and acne.
• Endometriosis. By suppressing the growth of endometrial epithelial cells, it leads to a decrease in the severity of menstrual bleeding
• Correction of water-salt balance. By taking the drug, the risk of peripheral edema is significantly reduced, and body weight is normalized.

How to take Yarina for endometriosis.

Taking Yarina for endometriosis does not differ significantly from its standard use as a contraceptive drug. The tablet is taken orally once a day at the same time for 21 days. After this time, a 7-day break occurs, the so-called withdrawal syndrome , which many people confuse with menstrual bleeding.

If hormonal contraceptives were not used before Yarina’s prescription , then the pills begin to be used on the first day of the menstrual cycle. When changing one hormonal drug to another, take Yarina the next day after taking the last tablet of the previous drug.

What is the hormonal drug Yarina?

Yarina is a drug that is prescribed for diagnosing endometriosis. Due to the content of estrogen and progesterone, with regular use it has the following effects:

• restores hormonal balance;
• stops tissue proliferation, helping to treat endometriosis;
• helps restore hormonal levels;
• allows the resorption of tumors;
• reduces the severity of bleeding during menstruation.

The drug is used in the same way as most oral contraceptives. The standard course involves taking it for 21 days and to facilitate control there is a special marking on the package. After completing the tablets, a break is taken for a seven-day break, after which the course is resumed again.

About the use of hormonal drugs for endometriosis >>

During a week's rest from the medicine, menstrual bleeding occurs. In some cases, a gynecologist may prescribe a regimen of taking the drug without interruption to achieve the following result:

• stopping menstruation, preventing ovulation;
• blocking the possibility of blood discharge into the pelvic area;
• causing reverse changes in the foci of endometriosis development.

The duration of treatment for endometriosis depends on the degree of development of the pathology, but the total duration of therapy does not exceed 6 months.

Contraindications for taking Yarina

There are many contraindications to the use of the drug. Let's look at the main ones:

• Individual allergic reactions to the components of the hormonal drug
• pregnancy, lactation and breastfeeding;
• thrombosis of deep veins, angina pectoris, cerebrovascular disorders, transient ischemic attacks;
• benign and malignant neoplasms of the liver and kidneys;
• hormone-dependent tumors of the breast and reproductive organs;
• diabetes mellitus type 1 and 2

You should take the drug with caution in case of obesity, porphyria and otosclerosis . In addition, it is worth noting heart and vascular diseases, gastric ulcers and hemolyticouremic syndrome.

Janine and Yarina: what's the difference?

These contraceptives differ primarily in the chemical composition and dosage of active ingredients. Accordingly, there are some discrepancies in the principles of action and indications for use. The information below will help you get acquainted with the features of the drugs.

The active ingredients of both combined contraceptives are hormones of the estrogen and progestogen groups. The composition of Yarin tablets includes:

• drospirenone – 3 mg;
• ethinyl estradiol – 0.03 mg.

Active components of Janine dragee:

• dienogest – 2 mg;
• ethinyl estradiol – 0.03 mg.

Mechanism of action

The combination of gestagens and estrogens has a contraceptive effect by inhibiting the maturation of eggs (ovulation) and increasing the viscosity of the mucus contained in the cervical canal. The last factor makes it difficult for sperm to get inside. While taking it, the menstrual cycle normalizes, the pain of menstruation decreases, and the production of sebum decreases.

• Drospirenone in Yarina additionally provides an anti-edematous effect, removing excess fluid from a woman’s body.
• Dienogest, one of the active components of the drug Janine, reduces the content of bad cholesterol in the blood.

The general and main indication for taking both contraceptives is the prevention of unwanted pregnancy. Yarina is also prescribed for the treatment of:

• seborrhea – increased oily scalp and dandruff;
• acne - acne rashes;
• swelling caused by hormonal imbalance.

Contraindications

Common to Janine and Yarina:

• predisposition to thrombosis - blockage of blood vessels with blood clots;
• the presence of precursors of thrombosis, such as angina pectoris (narrowing of the coronary arteries);
• suffered a heart attack or stroke (consequences of thrombosis);
• pregnancy;
• breastfeeding period;
• intolerance to the components of the product;
• malignant or benign tumors of the genital organs, liver, mammary glands;
• diabetes mellitus accompanied by vascular disorders;
• inflammation of the pancreas (pancreatitis);
• migraine – intense systematic attacks of headache;
• smoking, especially over the age of 35;
• vaginal bleeding of unknown origin.

Yarina is also contraindicated in women with renal failure.

Side effects

Janine and Yarina, especially at the addiction stage, can cause side effects such as:

• nausea, vomiting;
• mood swings;
• headaches, dizziness;
• decreased sex drive;
• swelling combined with soreness of the mammary glands;
• allergy.

Release forms and price

The cost of Yarin tablets depends on their quantity in the package:

• 21 pcs. – 1119 rubles;
• 63 pieces – 2892 rubles.

Dragee Janine can be purchased at the following prices:

• 21 pcs. – 1065 rubles;
• 63 pieces – 2491 rubles.

Contraindications

All tablets taken orally pass through the digestive system and are excreted through the intestines and urinary tract. Often the most important contraindications for taking hormonal pills are diseases of the internal organs.

Yarina is contraindicated in the following situations:

• vascular disorders and diseases that increase the risk of blockage of arteries and veins;
• serious problems in the liver, kidneys and pancreas;
• endocrine diseases;
• oncological pathology of any localization;
• smoking;
• migraine or any headaches of unknown origin;
• pregnancy and lactation;
• uterine leiomyoma and gynecological diseases for which estrogens cannot be used.

Taking hormonal contraceptives has a pronounced effect on all organs and systems of the female body. You cannot decide on your own about long-term use of oral contraceptives. If there is a need for birth control, you should seek medical advice.

Janine or Yarina - which is better?

The contraceptive effect of both drugs is the same, the cost is approximately the same, so they need to be compared according to other parameters:

• for acne it is better to use Yarina, since the dosage of hormones in it is higher and the drug is more effective (if the drug is poorly tolerated, you can take Jess - a complete structural analogue, but with a lower content of ethinyl estradiol);
• for varicose veins, Janine is preferable, containing only 2 mg of dienogest (a smaller dose of hormonal components reduces the risk of thrombosis);
• with fibroids (benign tumors of the uterus), the growth of nodes is inhibited by progesterone, respectively, Yarina is better in this case;
• If you have a deficiency of folic acid, it is advisable to choose Yarina Plus tablets, which additionally contain this vitamin.

Which is better - Janine or Yarina: reviews

Women's opinions about the effectiveness and safety of both contraceptives can help make the right choice.

Ekaterina, 20 years old: “The first contraceptive I took was Yarina. I took the pills for 3 months, but constantly felt nausea and headaches. After a complaint to the gynecologist about such side effects, the drug was replaced with Janine, which contains fewer hormones. Now there are no problems."

Elena, 32 years old: “For a long time I unsuccessfully struggled with acne. The last resort was oral contraceptives (Yarina), which coped with the task brilliantly. A pleasant bonus is reliable protection against unwanted pregnancy.”

Evgeniya, 27 years old: “I have varicose veins, so I was afraid to take OK. But the doctor convinced me, advising Janine that it contains very few hormones. I’ve been taking it for the second year, the disease has not progressed, and there are no other side effects.”

Reviews from doctors

Patients' opinions about contraceptives are subjective and largely depend on the individual characteristics of each woman. What do experts think about these drugs?

Molina N. O., gynecologist: “I consider oral contraception the best option for protection. For middle-aged women, I most often prescribe Yarina, as the most effective drug, and for young girls, tablets with less hormones - for example, Yarina and other analogues.”

Baranova I.V., gynecologist: “Zhanin and Yarina are proven, effective contraceptives. In the absence of contraindications, they are completely safe, so preliminary tests and examinations of the woman before prescribing are mandatory. “Prescribing” pills for yourself is unacceptable.”

Characteristics of Janine

Janine is a contraceptive drug, this is its main pharmacological property. The effect is achieved due to the simultaneous effect of ethinyl estradiol and dienoget on the body.

The first is an artificial analogue of estrogen. And it acts in a similar way, that is, it suppresses ovarian function and blocks the action of the hormone. Its main effect is to suppress the development of the endometrium.

Dienoget is a substance with the characteristics of progestins and testosterone levels. It has antiandrogenic properties and has a beneficial effect on lipid levels.

Janine is used to restore the menstrual cycle in women. This hormonal drug also relieves a woman of many external problems, such as acne and excess hair. It protects against various female diseases.

The body reacts to the medication relatively easily. Only a few experience mild side effects, such as headache and nausea. Some people notice hardening of the mammary glands at the beginning of treatment. But all these new sensations disappear with prolonged exposure to the drug on the body.

There are times when the body reacts more actively. Here you should stop taking Janine. This can be a severe cough, swelling, double vision, and sometimes thrombosis occurs. A second visit to the doctor is simply necessary.

Janine is a new modern contraceptive on the market, notable for its reliability. The medication has a number of advantages over other drugs used for endometriosis. It can be used for any degree of illness.

Janine is used to restore the menstrual cycle in women.

The drug is taken for 63 days, 1 pill per day. The break is 7 days. As practice shows, one course is enough to restore the functioning of organs. But the final word remains with the doctor.

Hormonal treatment of endometriosis

When using drugs for the treatment of endometriosis with the active ingredient danazol, pain decreases. It is prescribed to relieve pain, treat infertility due to endometriosis, and prevent the progression of the disease.

Hormonal treatment of endometriosis can be carried out using drugs with gestrinone. It has an antigonadotropic effect.

Side effects of danazol and gestrinone are associated both with the creation of a hypoestrogenic environment and with androgenic properties.

Comparison of drugs Janine and Yarina

Zhanine and Yarina are oral contraceptive drugs used to prevent unwanted pregnancy. They act on the body like this:

• suppress the ovulation process;
• prevent the process of implantation and fixation of the egg into the uterine endometrium;
• make the egg impassable for sperm.

Despite all the similarities in the mechanism of action, the drugs act differently on the body. The products have almost the same composition, their active substances are identical.

The differences between Yarina and Zhanine tablets are the content of drospirenone. Yarina is better tolerated by the body of women. Zhanine's price is from 1050 to 2530 rubles, Yarina's cost is from 1120 to 2940 rubles.

Which is better – Janine or Yarina

Yarina is a more modern drug, its activity is achieved due to the fact that the concentration of active substances in the product is increased. The advantage of the drug Yarina over Zhanine is the following: the time of penetration into the body, and therefore the period of concentration of substances in it, is shorter for Yarina than for Zhanine.

Yarina, unlike Janine, helps normalize metabolism. Janine is contraindicated for women with metabolic disorders. After the end of taking Yarina, its effect remains, and Zhanine is effective only during therapy.

Each medication performs its own functions and is intended for individual use. Before you start taking this or that drug, you need to consult a specialist. After checking all the readings, only he will answer what to prefer. Only then, after taking it, you need to observe your own body, its reaction to new substances.

Adverse reactions

"Zhanine", like any other drug, can cause a number of adverse reactions. In general, the drug is well tolerated by patients, but in some cases the following conditions are possible:

• Violation of psycho-emotional stability, manifested by nervousness, depression and irritability.
• Soreness and tension in the mammary glands.
• Headache.
• Disturbance in the functioning of the gastrointestinal tract, accompanied by nausea, diarrhea, flatulence, etc.
• Increase in body weight.

Adverse reactions appear both at the initial stage of treatment with the drug and after the end of the course.

“Janine” or “Yarina” - which is better according to reviews? More on this at the end of the article.