Askofen increases or decreases blood pressure: indications for use

• Composition of the drug
• Action on pressure
• Askofen for hypertension

Askofen is a drug with combined action. It is used as an analgesic and antipyretic.

Composition, release form

The drug is sold in pharmacies under the trade name "Askofen". Its non-proprietary international name is “ACETYLSALICYLIC ACID; PARACETAMOL; CAFFEINE."

Each tablet contains 3 active components:

• paracetamol (200 mg);
• caffeine (40 mg);
• acetylsalicylic acid (200 mg).

The excipients contained in the medication include the following:

• talc;
• povidone;
• Vaseline oil;
• stearic acid;
• potato starch;
• silicone emulsion;
• calcium stearate.

The drug is produced in the form of tablets. They have a light shade (white, cream) and a flat-cylindrical shape. There is no particular smell. The medication package contains 10 tablets.

Treating headaches with NSAIDs

For tension headaches and migraines, neurologists prefer nonsteroidal anti-inflammatory drugs (NSAIDs). Helps with headaches:

• acetylsalicylic acid (aspirin) – the maximum single dose is 2 tablets, but not more than six tablets 3-4 times a day;
• naproxen – you can take 2 tablets at a time, but no more than four tablets 2 times a day.
• diclofenac - take one tablet 3 times a day;
• indomethacin - can be taken one tablet 3 times a day or used in the form of rectal suppositories;
• Ketonal, ketanov, ketorol should be taken orally no more than 2 tablets at a time, 3-4 times a day.

According to reviews, Nurofen and Nimesil help well with headaches. Doctors recommend taking all drugs in this group after meals with plenty of water. The effect develops 0.5-2 hours after taking the drug. The duration of the analgesic effect is 4-6 hours. The tablets can be taken independently for no more than 4 days. Dexalgin acts quickly and effectively for headaches.

Pharmacological action, pharmacodynamics, pharmacokinetics

"Askofen" is considered a combination drug, its action is provided by each of the active components:

• paracetamol has an analgesic, anti-inflammatory, antipyretic effect;
• caffeine helps dilate the blood vessels of the heart, muscles, and kidneys. At the same time, it constricts the blood vessels of the brain and digestive organs. This component increases the reflex excitability of the spinal cord, excitation of the respiratory and vasomotor functions. Caffeine eliminates drowsiness, fatigue, and significantly increases performance;
• acetylsalicylic acid eliminates pain, relieves inflammation, reduces the risk of developing blood clots, and regulates the synthesis of prostaglandins.

The tablets are intended for oral administration. When using the tablets in question, about 90% of the drug is absorbed. The effect of the active components on the site of pathology begins a quarter of an hour after taking a single dose.

The medication in question is used for arterial hypotension because caffeine, which is one of its components, improves the condition of hypotension and eliminates some of its symptoms, such as headache, weakness, drowsiness, and decreased performance. The drug constricts the blood vessels of the brain and gives a boost of energy. Therefore, many patients consider Askofen a medicine for low blood pressure.

Patients often ask whether Askofen increases or decreases blood pressure. They started taking the hypotensive drug in question to increase blood pressure on their own, without instructions, for the reason that the medication contains caffeine. But Askofen should be used once when lowering blood pressure. The drug should not be used as part of a basic treatment regimen for hypotension.

The time to reach the maximum concentration of the substance in the serum differs for each active component:

• paracetamol – about an hour;
• acetylsalicylic acid – about 1 – 2 hours;
• caffeine – about 2.5 hours.

About 80% of the acids of the active substances are excreted through the kidneys.

Composition of the drug

The medicine contains acetylsalicylic acid, phenacetin and caffeine. In Ascaphen P, phenacetin is replaced by paracetamol.

1. Acetylsalicylic acid is a salicylic ester of acetic acid, which reduces body temperature, thins the blood, anesthetizes and relieves local inflammation.
2. Phenacetin normalizes body temperature, that is, does not allow it to drop below normal levels. It also has an analgesic effect. Due to the negative effects of phenacetin on the kidneys, it was replaced by paracetamol in the later formula of the drug - askofen P.
3. Paracetamol has a high safety profile. It is used as an analgesic and antipyretic, and also has a weak anti-inflammatory effect.
4. Caffeine activates the activity of the heart muscle, stimulates the nervous system, increases the heart rate, and dilates blood vessels. It is used to pacify headaches, migraines, and to stimulate breathing and cardiac activity. Less often to improve performance and eliminate drowsiness. Caffeine can increase blood pressure even in small doses. Therefore, askofen, which contains it, somewhat contributes to an increase in blood pressure.

Indications for use

Askofen tablets have an effect similar to the familiar aspirin. They provide a moderate analgesic effect and stabilize the temperature. The drug helps reduce the severity of anxiety symptoms in various diseases. The medication is especially effective in suppressing severe pain of various etiologies, as well as inflammation.

The main purpose of the medication in question is to eliminate pain. Doctors prescribe these tablets for the treatment of various diseases. Let us indicate what Askofen helps with:

• colds accompanied by fever;
• radicular syndrome of the lumbar, cervical, thoracic regions;
• severe toothache;
• pain syndrome during menstruation.

Indications for the use of "Askofen" are represented by the following pathologies:

• myalgia;
• pain of unknown etiology;
• neuralgia;
• pain in muscles and joints;
• increased frequency of migraine attacks;
• rheumatic pains;
• algodismenorrhea;
• headache;
• peripheral nerve damage;
• lumbago, thoracic radicular syndrome;
• toothaches.

Action on pressure

Does Ascofen increase or decrease blood pressure? The effect of the drug on the cardiovascular system is not mentioned in the drug annotation.

But if we analyzed the pharmacological action of its constituent components, we can draw the following conclusions:

• Acetylsalicylic acid slightly dilates blood vessels and reduces blood clotting, but this does not affect blood pressure;
• Phenacetin has no effect on blood vessels, blood flow or blood pressure.
• Paracetamol is effective for low blood pressure and useless for high blood pressure;
• Caffeine is the only component in the drug that increases blood pressure. Its dosage is enough to ensure that the change in blood pressure is noticeable and sustainable.

Analyzing the effect of the components of the drug, we can come to a conclusion.

The drug Askofen increases blood pressure in humans.

Therefore, it is useful for people with low blood pressure. Hypertensive patients should take it with caution, monitoring their levels.

The drug is unlikely to lead to a hypertensive crisis and other adverse consequences that hypertensive patients fear. The dose of caffeine it contains is not enough for this.

Askofen for low blood pressure is good because it eliminates dizziness, weakness and fatigue, drowsiness and lethargy, tones and improves performance. The drug may increase blood pressure in case of high blood pressure, so consult a doctor before use.

The medicine is prescribed for fever (increased body temperature) and pain syndromes:

• Toothache,
• Headache,
• Algodysmenorrhea (menstrual pain),
• Migraine,
• Neuralgia (pain in the area of ​​peripheral nerve innervation),
• Arthralgia (joint pain),
• Myalgia (muscle pain).

Contraindications

"Askofen" should be used according to the indications of a specialist with strict adherence to the dosage. Superficial self-medication poses a health risk. The instructions contain contraindications for taking the medication, which must be taken into account when starting a therapeutic course using the medication in question.

Medical restrictions on the use of the drug include:

• aortic aneurysm;
• chronic damage to the liver and kidneys;
• stomach ulcer;
• the patient’s tendency to develop erosion and bleeding of the digestive tract;
• hemorrhagic diathesis;
• portal hypertension;
• progressive glaucoma;
• asthma, which was provoked by the use of acetylsalicylic acid;
• deficiency of glucose-6-phosphate hydrogenase;
• children's age (up to 15 years);
• nervous disorders;
• intolerance to the active components of the drug;
• pregnancy and lactation;
• cardiac ischemia.

Features of use

According to the instructions for use, adults can take no more than 1-2 tablets per day to relieve pain and other symptoms. The maximum dose of the drug per day should not exceed 6 tablets. If a medicine is prescribed for other indications (accelerating blood flow, increasing blood pressure, etc.), then its dosage is calculated by the attending physician based on individual indications.

The duration of treatment with Askofen is about one week. To suppress intense pain, it is recommended to use 2 tablets at once.

Askofen is in most cases well accepted by the body. In this case, the medicine can cause the following side effects:

• an allergic reaction that occurs due to exposure to individual components (in particular, caffeine);
• heartburn;
• attacks of nausea;
• exacerbation of certain diseases (bronchial asthma and others);
• dyspeptic disorders;
• dysfunction of the liver and kidneys;
• skin rashes;
• peptic ulcer of the stomach and duodenum.

Instructions for use

The tablets in question are prescribed for therapy in adolescents and adult patients. In any case, the patient must follow the daily dosages indicated in the instructions to avoid accidental overdose. Due to the fact that taking Askofen can cause disruption of the functioning of the gastrointestinal tract, the tablets should be taken after meals. Doctors recommend drinking the drug with plenty of alkaline, carbonated water, and milk.

Adults can take 1–2 tablets, leaving a 4-hour break between doses. The maximum permissible dosage per day is 6 tablets. To relieve acute pain, it is enough to drink 2 tablets at a time.

The duration of the therapeutic course differs depending on the severity and course of the disease. The duration of use should not exceed 5 days if the medicine is prescribed for pain relief. If the medication is prescribed as an antipyretic, the duration of the course of treatment should not exceed 3 days.

The annotation for “Askofen” does not contain clear instructions about the dosage in which it reduces blood pressure or, on the contrary, increases it, but at the same time, due to the caffeine content in the drug, it should be taken with caution by those who suffer from arterial hypertension (high blood pressure).

Migraine tablets

Bulgakov's Pontius Pilate, exhausted by attacks of hemicrania, was sure that there was no salvation from a headache that spread to half his head. Fortunately, a lot has changed since then, and relief from migraines has finally appeared. What drugs belong to anti-migraine analgesics and how to select them - this will be discussed in the last article of the series on painkillers.

Not just a headache

Headache can have different origins, and, in fact, the selection of the drug depends on it. Experts are still arguing about the mechanism of development of migraine headaches.

It is known for sure that during an attack, the blood vessels of the brain dilate, as a result of which the blood flow to it increases.

That is why sufferers who try to stop a migraine attack with the help of popular antispasmodics, such as Spazmalgon, end up with even more severe pain. After all, antispasmodics contribute to the dilation of blood vessels, including the brain, which means they act together with migraine, and not against it!

There is no need to try to get rid of migraines with the help of combined products containing papaverine (Andipal), drotaverine (No-shpalgin or No-shpa) and other antispasmodics. They are unlikely to help, and if they do provide relief, it will not be for long. Those who periodically experience migraine attacks should pay attention to triptans and drugs containing ergotamine. They are among the targeted anti-migraine drugs.

Triptans: the “correct” effect on blood vessels

The subgroup of antimigraine analgesics called triptans is still very young: its first representative, sumatriptan, saw the world in 1991. And yet, over a quarter of a century, he managed to become famous and become the gold standard for migraine treatment.

The mechanism of action of triptans is aimed directly at the process that triggers pain. Drugs in this group interact with special receptors located in the blood vessels of the brain, which leads to their narrowing.

Thus, triptans do not exhibit the direct analgesic activity characteristic of traditional analgesics, and yet they still work. This fact once again proves that migraine is not an ordinary headache that can be easily calmed with paracetamol or aspirin.

In addition to sumatriptan, other drugs from the triptan group are registered in Russia. They are easy to “calculate” among the medicinal variety - the international names of these drugs always end with -triptan: naratriptan, frovatriptan, eletriptan.

All triptans work in the same way, but the effects may vary depending on the individual's sensitivity. I will add that triptans are most effective if taken in the early stages of a migraine, at the very beginning of the attack. 2 hours after the first dose, the dose can be repeated to “fix” the result.

Ergot alkaloids

A pest fungus, ergot, likes to live on some cereal crops, such as wheat or rye. It produces a large amount of toxic substances - alkaloids, which in low doses can have a wide variety of effects on the human body.

Ergotamine has found widespread use in medicine. It, like triptans, interacts with receptors that constrict blood vessels in the brain, and also exhibits a direct vasoconstrictor effect on vascular smooth muscles. In this regard, ergotamine preparations are widely used as anti-migraine analgesics.

However, if you start looking for a medicine called “ergotamine” in pharmacies, you will be disappointed. Ergotamine belongs to the so-called list A, which includes drugs and poisons, and is sold exclusively with special doctor’s prescriptions, equipped with many seals and signatures.

Combination preparations containing ergot alkaloids, such as Nomigren, are much more accessible. It contains a complex of ergotamine (0.75 mg), an analgesic, antispasmodic, antiemetic and caffeine. However, Nomigren has a solid list of contraindications and side effects.

Russian industry produces another anti-migraine analgesic with ergotamine - Cafergot. In addition to 1 mg of ergot alkaloid, it contains caffeine, which enhances the effect of the main component.

There is one important aspect to remember regarding medications that contain ergot alkaloids. Ergotamine and its salts (in particular, ergotamine tartrate) stimulate uterine contractions, so they are strictly contraindicated during pregnancy.

So what should you choose?

As you can see, there are not so few drugs for treating a migraine attack. Which one should you choose? The answer to this question depends on the severity of the headache - there is even a so-called stratification of anti-migraine drugs according to the strength of the analgesic effect.

For moderate attacks, it is recommended to take non-steroidal anti-inflammatory drugs (NSAIDs) (eg paracetamol, ibuprofen, ketoprofen) or any of the triptans. If migraines cause severe headaches, it is better to use triptans or products containing ergotamine.

If the situation can be called very severe, the choice is narrowed to ergotamine or opioid analgesics. I note that the last option, given the strictness of domestic healthcare in the field of opioid trafficking, is practically impossible in Russian reality.

And yet, despite the clear division of anti-migraine drugs according to effectiveness, each case is individual. This means that each patient, together with his doctor, must select his own personal regimen for relieving migraine pain.

Marina Pozdeeva

Photo thinkstockphotos.com

Products by topic: Paracetamol, Ibuprofen, Ketoprofen, Caffetamine, Sumatriptan, Imigran, Rapidmed, Sumamigren, Amigrenin, Relpax

Side effects

During intensive therapy with the drug in question, the patient may experience discomfort. Doctors explain their occurrence by a period of adaptation of the drug in a weakened body. The side effects that occur when taking tablets are not local. They can manifest themselves in various internal organs and systems.

Important: The occurrence of any side effects requires temporary cessation of use of the tablets. Additional consultation with your doctor is required.

The following side effects must be indicated:

• in the area of ​​the gastrointestinal tract organs, gastrointestinal bleeding, symptoms of dyspepsia, vomiting, diarrhea, renal and liver failure may appear;
• in the area of ​​the cardiovascular system, tachycardia, arterial hypertension, arrhythmia, and nausea appear;
• in the area of ​​the nervous system, depression, drowsiness, dizziness, and confusion are observed;
• Quincke's edema, local allergic reactions, bronchospasm, and anaphylactic shock occur on the skin.

Experts do not recommend using the medication in question for a long period. They explain this by the fact that it can provoke the development of chronic diseases (deafness, Stevens-Johnson syndrome, tinnitus, decreased platelet aggregation, blindness, hypocoagulation, hemorrhagic syndrome).

Treatment of headaches with nootropic drugs

Improving brain nutrition contributes to the severity of headaches. For this purpose, neurologists prescribe Mexidol. This is a drug to protect body cells from various types of influences, including destruction by free radicals.

Mexidol also has the following effects:

• antihypoxic – increases resistance to hypoxia and improves the utilization of oxygen that circulates in the body;
• stress-protective – protects life support systems from the negative influence of an emotional nature;
• nootropic – has a specific effect on the higher mental functionality of the brain;
• antiepileptic – relieves muscle cramps of various origins;
• anxiolytic – reduces anxiety, feelings of restlessness and fear.

Piracetam is also used for headaches. The drug has the following effects:

• affects the processes of metabolism and blood circulation in the brain;
• increases glucose utilization;
• stimulates redox processes;
• improves regional blood flow in ischemic areas of the brain.

Glycine helps patients with headaches. It increases brain activity, reduces anxiety, and improves sleep quality. Phenibut will relieve headaches, depression and anxiety.

If you have a headache for the first time, rest and take a non-steroidal anti-inflammatory drug tablet. If it is ineffective, you can take an antispasmodic or a combination drug. If your headache gets worse, call the Yusupov Hospital. Headache therapy with the help of modern pharmacological drugs and non-drug treatment methods is carried out by doctors at the Yusupov Hospital after a comprehensive examination of patients. Before prescribing an anesthetic, neurologists rule out organic brain damage and other diseases that cause headaches.

Author

Natalya Andreevna Kondrashina

Physiotherapy doctor, 1st category doctor

Overdose

Exceeding the dose of Askofen indicated in the instructions may cause an overdose. Its signs are:

• paleness of the skin;
• nausea, vomiting;
• sweating;
• pain in the gastrointestinal tract;
• tinnitus;
• tachycardia;
• bronchospasm;
• collapse;
• drowsiness;
• breathing problems;
• convulsive state.

If signs of poisoning with this drug appear, you should urgently call an ambulance. Usually the victim’s stomach is washed and allowed to take adsorbents.

Side effects

• First of all, any side effects of the drug affect the digestive system. In these cases, there is a noticeable deterioration in the condition of the mucous membranes, an increase in the area of ​​erosion, and bleeding may occur. All this is complicated by painful sensations, as well as nausea, sometimes turning into vomiting.
• In rare cases, Askofen can cause disruption of normal liver and kidney function. And also change the composition of the blood. Intolerance to some components of this pharmacological drug may manifest itself as bronchospasms and rashes on the surface of the skin.
• An overdose is manifested by pain in the stomach and other disturbances in the digestion of food, disturbances in the functioning of the organs of vision and hearing. If the dose was exceeded too much, then coma is quite possible. In case of severe poisoning in such a situation, it is necessary to immediately perform gastric lavage and take many other measures.

1. In case of overdose, the risk of occurrence and subsequent development of reactions such as nausea, ringing in the ears and dizziness of varying strength increases significantly. A similar reaction of the body is possible with mild poisoning
2. In case of severe poisoning, muscle cramps, a feeling of lethargy and drowsiness, inhibition of reactions, and collapse may be observed.
3. In case of subsequent intensification, even disturbances in the functioning of the respiratory system may be observed. In this situation, you should immediately contact a doctor.

As the main therapy, the balance of water and salts in the body should be constantly monitored. An increase in the concentration of alkaline compounds promotes the removal of acetylsalicylic acid from tissues.

Interaction with other drugs

When prescribing a specific complex therapy regimen, a specialist must take into account certain limitations. It is important to know the specifics of drug interactions between Askofen-P and other medications, because the active components of other drugs can disrupt the therapeutic effect of certain pharmacological groups.

You need to know these types of interactions:

1. "Askofen" enhances the effect of indirect coagulants, reserpine, heparin, steroids, and hypoglycemic drugs.
2. The medication in question reduces the effectiveness of antihypertensive drugs, Spironolactone, Furosemide, and anti-gout drugs.
3. The use of acetylsalicylic acid provokes the appearance of side effects of such drugs as: non-steroidal anti-inflammatory drugs, corticosteroids, Methotrexate, non-narcotic analgesics, sulfonylurea derivatives.
4. You cannot combine Askofen with taking barbiturates, drugs for epilepsy, Zidovudine, Rifampicin.
5. Under the influence of caffeine, the absorption of Ergotamine is accelerated, and Metoclopramide promotes the penetration of paracetamol into the systemic bloodstream.

Interaction with other drugs

enhances the effect of heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic agents.
Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, anti-gout drugs that promote the excretion of uric acid.

Increases the side effects of glucocorticosteroids, sulfonylurea derivatives, methotrexate, non-narcotic analgesics and non-steroidal anti-inflammatory drugs.

The combination of the drug with barbiturates, antiepileptic drugs, zidovudine, rifampicin and alcohol-containing drinks should be avoided (increases the risk of hepatotoxic effect).

Under the influence of paracetamol, the elimination time of chloramphenicol increases 5 times. Caffeine accelerates the absorption of ergotamine.

Salicylamide and other stimulants of microsomal oxidation promote the formation of toxic paracetamol metabolites that affect liver function. Metoclopramide accelerates the absorption of paracetamol. When taken repeatedly, paracetamol may enhance the effect of anticoagulants (dicoumarin derivatives).

The drug enhances the effect of heparin, hormones, and hypoglycemic agents. When taken simultaneously with antihypertensive drugs and diuretics, their effectiveness may decrease. Askofen is not recommended to be combined with barbiturates and antiepileptic drugs - there is a high probability of liver damage.

Use during pregnancy

The medication in question is strictly prohibited for pregnant women to take during the first and third trimester. During this period, Askofen can cause an increase in uterine tone.

In the second trimester there are no particularly strict restrictions on the use of the drug. A pregnant woman is allowed to take Askofen tablets only if the benefit to the mother significantly outweighs the likely harm to the fetus.

During breastfeeding, doctors recommend that mothers stop taking this medication. If the doctor prescribes intensive therapy with Askofen, you should stop breastfeeding (temporarily).

Is it possible for pregnant and lactating women

The use of tablets is excluded, especially in the 1st and 3rd trimester. In the second trimester, a single dose of Askofen-P is allowed, but only if the benefit is greater than the probable harm.

As numerous studies have shown, aspirin can negatively affect the course of pregnancy, provoke placental abruption and miscarriage, or lead to post-term pregnancy and other undesirable consequences.

The ban also applies to the period of breastfeeding. Acetylsalicylic acid enters the baby's body through mother's milk. In particular, this affects blood clotting and bleeding increases. This sometimes causes hematomas to appear, which indicate internal hemorrhage. If there is a need to prescribe the drug to a nursing mother, then the baby is transferred to artificial formulas during therapy.

special instructions

• With prolonged use of the medication in question, its therapeutic effect decreases. In addition, new diseases of the body may develop.
• Carrying out intensive therapy requires monitoring blood pressure, liver and kidney function, and uric acid concentration (this is necessary to prevent gout attacks.
• It is not recommended to use Askofen for therapeutic purposes in childhood.
• If surgery is to be performed, you should temporarily stop taking the medication in question.
• Do not exceed the dosage specified in the instructions.

Pharmacological properties

• Askofen belongs to the category of medications that act through the action of the three active components listed above.
• The use of this pharmacological agent allows you to reduce, and sometimes completely eliminate, the manifestations of pain in the shortest possible time.
• With its help, you can reduce body temperature from elevated to optimal, as well as normalize blood pressure.
• Each of the components included in the composition has a specific effect, but in combination they allow you to create a more powerful formula for eliminating pain from a wide variety of causes.

1. Aspirin regulates the production of prostaglandins, slows down platelet aggregation, makes the blood more fluid, and prevents the appearance of blood clots (clumped blood components) in the lumen of blood vessels.
2. Paracetamol , just like the previous compound, has an analgesic, anti-inflammatory and antipyretic effect. Allows you to influence the body's thermoregulation center located in the hypothalamus. This way the temperature drops and inflammation is relieved.
3. Caffeine has an invigorating, if not stimulating, effect on the body, and also stimulates the receptors of the respiratory system, dilates blood vessels, and increases endurance. This compound can increase activity not only physical, but also mental. This component increases blood pressure and also improves blood flow to the head.

Analogs

If the patient has contraindications to the use of Askofen, the doctor prescribes another drug. In order not to harm the patient’s health, experts select an analogue that does not have the same contraindications as the medicine in question.

Analogues are also prescribed in the absence of significant improvements or the appearance of new health complaints.

The following drugs have a similar effect:

• "Excedrin";
• "Acifein";
• "Citrapar";
• "Aspirin";
• "Migrenol Extra";
• "Kofitsin plus";
• "Citramarine".

Price and analogues

The following drugs are similar in their effects on humans and active components:

• Excedrin, which is a combination drug. It contains the same compounds

  I think that in askofen, except that the ratio is different. The action of the drug is aimed at eliminating inflammation, and therefore the increased temperature that accompanies this process, and pain.

• Citramon P , which contains exactly the same components. All this together affects the central nervous system and thermoregulation of the body. Thus, the heat that often accompanies inflammatory processes is reduced and pain is relieved.
• Citramon ultra , which is a drug that has analgesic and anti-inflammatory effects on tissues and the nervous system. This drug differs from others in its rather large list of side effects, but there are also many indications for its use. So before taking it, you should consult a specialist.
• Citrapar , which is a combination drug. The product contains caffeine, paracetamol and acetylsalicylic acid. Most of all the last ingredient, and least of all caffeine.
• Migrenol Extra , which, like everything else, is a medicine that can eliminate moderate or mild pain. In addition, its use can help with the febrile syndrome that accompanies the acute form of respiratory diseases. The active components of this pharmacological drug are all those compounds that are given in all the remedies that were described above.

If it is necessary to change the drug, it must be done after talking with your doctor.

The cost in pharmacies is as follows:

Ten tablets do not exceed twenty rubles. The cost of twenty tablets can reach 45 rubles.

Reviews

People often use the tablets in question to normalize blood pressure. There is no specific dosage in the instructions for using Askofen for hypotension. But people who used it for low blood pressure noted a noticeable increase in ability to work, decreased fatigue, elimination of headaches, absent-mindedness, and weakness from low blood pressure.

Some reviews contain information about Askofen's ability to improve the condition when weather conditions change. Changes in the weather often provoke the following unpleasant sensations:

• lethargy;
• numbness of the limbs;
• Bad mood.

Properties of the drug

What Askofen is needed for depends on the individual characteristics of the patient. The medicine is prescribed to suppress pain, increase blood pressure and restore body temperature. This combined effect is achieved due to the composition of the drug. Moreover, each of the components has a specific effect on the body.

The popularity of Askofen for headaches is due to the fact that one tablet contains 0.2 grams of paracetamol. This substance has 3 different effects on the body:

• antipyretic;
• analgesic (pain reliever);
• anti-inflammatory.

Paracetamol acts directly on the thermoregulation center located in the hypothalamus.

Approximate price in Russia

"Askofen" is often used for hypotension for the reason that it not only alleviates the condition, but is also quite cheap. And buying from an online pharmacy will be even cheaper.

We will indicate the approximate cost of the medicine in different pharmacies in Moscow:

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Ivan Grekhov

Graduated from the Ural State Medical University with a degree in General Medicine. General practitioner

Can Askofen be used during pregnancy?

Askofen is an anticoagulant drug, available in tablets from white to light yellow, light gray, milky shades. The tablets are packaged in plastic blisters of 10 pieces, the blisters are in a cardboard box, along with instructions for use. Even a single dose of the drug affects the composition of the blood, changing the number and balance of platelets. This thins the blood, stimulates blood flow, impairs clotting, and turns out to be a good prevention of hypertension, blood clots, and hypoxia.

The main active ingredient of Askofen is acetylsalicylic acid. The drug is a complete analogue of the well-known Aspirin, therefore it has the same indications and contraindications for use. The admissibility of taking the drug by pregnant women depends on the period of gestation.

In 1st trimester

The use of the drug is prohibited. The main active ingredient of the drug, acetylsalicylic acid, has a negative effect on the fetus. Use of the drug by pregnant women in the first trimester can lead to:

1. Cleft palate.
2. Other fetal malformations.

The drug is not prescribed - specialists try to find more adequate drug replacements that are safe for the mother and fetus. Since the likelihood of developing pathology caused by Askofen is very high.

In the 2nd trimester

The drug is conditionally allowed to be used - it is prescribed if there are absolute indications. The potential benefit to the mother from taking it must outweigh the potential risk to the fetus. Even such indications allow only a single dose of one recommended dose of the drug. Systematic treatment is prohibited.

In the 3rd trimester

The use of the drug is completely prohibited, as it stimulates the production of prostaglandin, which relaxes muscles and suppresses muscle contraction. The described effect leads to inhibition of labor, its lethargy, and delay.

The second possible harm to the fetus is the closure of its ductus arteriosus. The described phenomenon can cause pulmonary pathologies of various types, most often - pathological proliferation of pulmonary vessels, increased blood pressure in the pulmonary circulation. The expectant mother has an increased chance of suffering from bleeding during childbirth.

Lactation is also a contraindication for use. Acetylsalicylic acid is excreted in breast milk. Once in the child’s gastrointestinal tract, it is absorbed, absorbed by the child’s body, and causes blood thinning. The phenomenon can disrupt blood composition, balance, platelets, reduce clotting, and provoke fetal bleeding. When there is a need to prescribe Askofen to a breastfeeding mother, breastfeeding should be stopped for the entire period of treatment plus one more day.

General information about the drug

The drug is produced in tablets, the main components of which are:

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• Phenacetin. Eliminates inflammatory processes and removes heat.
• Acetylsalicylic acid. Eliminates pain, swelling and inflammation.
• Caffeine. Increases the performance of the human body and improves brain function.

Thus, the components of Askofen, interacting with each other, have antifever, analgesic and anti-inflammatory effects. Caffeine activates the nervous system, stimulates motor activity, enhances the healing effects of analgesics and weakens the activity of narcotic and sleeping pills. In this regard, when using Askofen, it is important to take into account its compatibility with other medications, otherwise the risks of developing side symptoms increase significantly.

Compound

Askofen owes its healing properties to its composition. It is not unique, but it can definitely be called effective.

1. Caffeine. Relieves fatigue, stimulates mental and physical activity, and has a tonic effect. Moreover, caffeine has a vasodilating effect.
2. Paracetamol. Relieves swelling, heat and eliminates pain.
3. Acetylsalicylic acid. Normalizes temperature, has anti-inflammatory and analgesic properties.

Tablets during pregnancy for headaches

The drug is potentially dangerous for pregnant women.

Askofen should not be taken in the first and third trimester, and in the second, only if absolutely necessary, you are allowed to take the medicine, but no more than once.

If you do not follow these recommendations in the first trimester, there is a risk of serious developmental defects in the fetus (in particular, newborn boys may develop abnormalities in the structure of the genital organs in the form of cryptorchidism, and hepatogenic encephalopathy is possible in both sexes).

In the third trimester, the drug can lead to the development of hypertension in the unborn baby, as well as inhibition of the delivery process. Obviously, no expectant mother wishes such problems for her child.

The medication is strictly contraindicated in the first and third trimester of pregnancy, as it can cause increased uterine tone. In the second trimester, such pharmacological prescription is not prohibited, but Askofen-P tablets can only be taken if the benefit to the mother is higher than the potential threat to the health of the fetus. During lactation, it is also better to refrain from such treatment, or temporarily stop breastfeeding for the period of intensive therapy.

As you know, self-medication is generally contraindicated, as it can do more harm than good. What can we say about the time when a woman is expecting a child. Anyone should consult their doctor before taking Askofen. In addition, according to the instructions that come with the tablets, this drug should not be taken by women who are in an “interesting position,” especially in the first trimester of pregnancy.

Many medications for nine months are taboo for the expectant mother. You should be especially strict about immunostimulating drugs that contain alcohol or drugs that are based on interferon. They can be taken under strict medical supervision and not earlier than in the third trimester.

Aspirin and its derivatives are strictly prohibited throughout pregnancy - these drugs, by the way, include Askofen, as well as Citramon. If they enter the body of a pregnant woman in the first trimester, they can seriously harm the baby, because they thin the blood, and this is fraught with serious malformations of the fetus.

In principle, I believe that it is better to take a pill than to suffer (nothing criminal will happen), but in this case, it is quite possible to do without pills.

The use of Citramon and Askofen during pregnancy is undesirable - when used in the first trimester it leads to fetal malformations; in the third trimester - to inhibition of labor (inhibition of Pg synthesis), to closure of the ductus arteriosus in the fetus.

The headache most often comes from the fact that toxins get from the cells into the blood - and in a pregnant woman they get there because the body begins to spontaneously cleanse itself so that the baby develops in a healthy body. Hence toxicosis and headaches.

The best way to remove toxins from the body is to drink more water - up to 2 liters per day.

Your head won't hurt - drink more!))))))))))))

Try to relieve pain with non-medicinal methods.

Everything that is listed here in the question and in the answers is not allowed.

The cause of a headache can even be poisoning with mercury vapor or lead, high or low blood pressure, or anything!! !

Askofen is an undesirable drug during pregnancy. The fact is that it can be called combined, because the essence of its “work” is to reduce fever and relieve pain.

This medicine consists of three main components, each of which performs certain “functions”. These are paracetamol, caffeine and acetylsalicylic acid. Each of these components performs a specific role. Individually, these substances are not capable of fighting colds and viral diseases, but together, they easily relieve a person of unpleasant symptoms.

Askofen is one of the drugs that is manufactured exclusively in tablet form. Their color is white, in some cases it has a yellowish or even pinkish tint. In fact, the drug is not an antibiotic, so it’s worth figuring out whether it’s possible to take Ascofen during pregnancy, and if there are any specific contraindications?

The fact is that it contains a component such as acetylsalicylic acid, which perfectly relieves pain where there is an inflammatory process. But, in addition, this component is capable of thinning the blood, and this in turn is fraught with the formation of blood clots. Caffeine, which is also contained in the drug, can become a stimulant for the vasomotor and respiratory centers.

But at the same time, it perfectly relieves fatigue and increases performance. Moreover, we are talking not only about physical, but also mental labor. It is necessary to take into account the fact that the tablets significantly increase blood pressure and can stimulate blood flow. Askofen is allowed during pregnancy. It should be understood that for some people this is simply unacceptable. In this case, we are talking not only about pregnant girls.

Askofen in the early stages of pregnancy is able to cope with colds and flu. Moreover, he can relieve headaches and toothaches. Naturally, its wonderful properties extend to other patients. In some cases, the drug is also prescribed for migraines. The drug has a positive effect on rheumatic diseases and even neuralgia.

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Therefore, one can talk about the medicine quite widely. Despite the content of such components, it can be safely used by pregnant women. But this, of course, should be done with some caution. Particularly when it comes to the first trimester. Askofen during pregnancy is often used to treat colds.

Askofen during pregnancy instructions for use. The recommended dosage is one tablet several times a day. What is meant by this expression? In this case, everything depends solely on the type of pain and the condition of the patient himself. Askofen during pregnancy helps to cope with various types of pain.

True, there are some recommendations for use; it is advisable that the “use” of the medicine be accompanied by a large amount of liquid. The course of treatment with this drug should not exceed 5 days. Naturally, if we are talking about a pregnant girl, then the medicine should be used under the guidance of a doctor.

Contraindications to the use of askofen during pregnancy

Ascophen also has contraindications during pregnancy. It should not be used by people with high blood pressure. It is especially important to pay close attention to the dosage and duration of use. Treatment cannot be continued after the allowable period of 5 days has been completed. More than eight tablets per day can cause an overdose of the drug.

Therefore, it should be taken only after certain doctor’s indications. But in this case we can talk not only about pregnancy. More precisely, about the effect of the drug on the body of the expectant mother and fetus. After all, even in the presence of a peptic ulcer, problems with the gastrointestinal tract and liver dysfunction, the use of the medicine is strictly prohibited. This may somewhat aggravate the current situation, especially when using askofen during pregnancy.

Use of askofen during pregnancy

The use of askofen during pregnancy should be under the supervision of the attending physician. After all, the instructions contain a clause that states that using the medicine in the first trimester is prohibited. This is fraught with consequences for the fetus. So it is not recommended to use the drug during this period, so as not to really cause irreparable harm.

Askofen is able to remove pain, but only that which is moderate in its kind. So, we are talking about migraines, toothache, menstruation, etc. It is often used when there is a sharp increase in body temperature. But you can use it for its intended purpose only after consulting a doctor.

Taking askofen during pregnancy

Taking askofen during pregnancy occurs under the supervision of a doctor. After all, there are many contraindications for the expectant mother. Therefore, before using anything, you should consult. In general, there are no special contraindications. The main thing is not to go beyond what is permitted and not to use medicine for high blood pressure.

It is advisable that the dose does not exceed 2-3 tablets per day. Moreover, the medicine should be taken after meals. As for the duration of treatment, in this case everything depends solely on the existing problem. But, nevertheless, it is not advisable to take askofen during pregnancy for more than 5 days.

Askofen is considered acceptable during pregnancy, but you should consult your doctor before using it. Despite its popularity and high efficiency, it cannot be used without consultation. After all, it has a number of side effects, and in general, it is not suitable for every person. Especially if there are problems with the gastrointestinal tract.

Any medications not prescribed by a doctor are not recommended. And the noshpa for headaches never helped.

Girls, I understand that they are unwanted. But I didn’t have the strength to endure it. Now I just want to know how critical it is to take 1 tablet.

I drink. Don't be afraid and don't listen to anyone. The headache cannot be tolerated.

Juliaska, is there nothing written about this in the annotation?

Paracetamol is recommended for headaches in B.

Kosha, today I read that you don’t need to drink in the 1st and 3rd trimester. But some girls seemed to drink it. It is clear that I will not drink it again. But what to do with yesterday’s 1 tablet? After all, this is not a systematic method?

Juliaska, don’t worry, nothing will happen from one pill :) People don’t even take that, if necessary.

Girls, the Asterisk magically helps with weights and ears!

Indications and contraindications

These tablets are often taken for various pain syndromes. That is, Askofen will help with headaches, calm migraines, neuralgia, arthralgia, myalgia. In addition, it will reduce severe pain during menstrual periods. But at the same time, Askofen has both indications and contraindications for use, which should be taken into account when purchasing a medicine.

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The instructions for the drug prohibit its use in case of the following ailments:

• tendency to gastrointestinal bleeding,
• stomach and duodenal ulcers,
• renal-liver failure,
• hypocoagulation,
• portal hypertension,
• asthma,
• some of the heart and nervous system diseases.

Pregnant women should avoid taking the medication and should not drink Ascophen during lactation. Those whose body cannot tolerate any of its components should also be careful with it.

Children under 15 years of age are also not recommended to use these tablets.

Composition and application features

The medicine consists of three main components:

1. acetylsalicylic acid. Relieves inflammation, reduces body temperature, has blood-thinning and analgesic effects;
2. paracetamol is a drug for symptomatic therapy, which means that it does not cure, but only relieves unpleasant symptoms in the form of fever, pain, inflammation;
3. caffeine. A psychostimulant often used in pain medications.

Caffeine will help answer the question of whether Askofen increases or decreases blood pressure. After all, it is the component that can increase blood pressure.

Relieves attacks of pain of various etiologies, stimulates the activity of the cardiovascular, respiratory and central nervous systems, eliminates drowsiness. This element of the drug accelerates the pulse, promotes vasodilation, has a stimulating effect on the nervous system, and also accelerates the work of the heart muscle.

When is Askofen used:

• in persons over 18 years of age, used for migraines, neuralgia of various kinds, headaches and toothaches, myalgia, arthralgia, lumbago, algodismenorrhea, thoracic radicular syndrome;
• in patients over 15 years of age: increased body temperature due to acute respiratory viral infections, acute respiratory infections and other infections.

Admission is completely excluded if you have the following health problems: tendency to bleeding in the gastrointestinal tract, liver and kidney dysfunction, glaucoma, vitamin K deficiency, portal hypertension, allergy to one of the components of the drug, hemorrhagic diathesis, ulcers in the acute stage, tendency to increased excitability , as well as other neurologically and mentally unstable conditions; dissecting aortic aneurysm, diseases of the cardiovascular system of an organic nature, pregnancy and lactation.

The medical drug Askofen-P in tablets acts like classic Aspirin, provides a moderate analgesic effect and stabilizes the temperature. It is very problematic to completely cure the disease, but you can significantly reduce the severity of anxiety symptoms. This is especially true for severe attacks of pain of various etiologies and inflammation. Indications for the use of tablets are as follows:

• more frequent migraine attacks;
• neuralgia;
• pain of unknown etiology;
• myalgia;
• rheumatic pains;
• arthralgia;
• toothache;
• thoracic radicular syndrome, lumbago;
• headache;
• algodismenorrhea.

Askofen-P tablets are prescribed equally to adults and children, and in all clinical situations it is necessary to follow the prescribed daily doses and avoid dangerous cases of overdose. Since there is a high probability of impaired activity of the gastrointestinal tract after taking the medication, it is recommended to take it after meals, drink plenty of milk, alkaline or carbonated water.

If Askofen-P tablets are prescribed by the attending physician in childhood, the above dosage is allowed for patients over 15 years of age. At an earlier age, this particular medication is strictly contraindicated, as described in detail in the instructions for use. It is better not to give Askofen-P tablets to children, since the ingredients of the medicine can negatively affect the functioning of internal organs and systems.

This drug is recommended for headaches, colds, and neuralgia. It should be noted that the use of Askofen is increasingly being replaced by the use of Askofen P and Askofen L, which is due to the greater safety of paracetamol compared to phenacetin, as well as a more effective combination of components included in these drugs.

Askofen P is prescribed for:

• moderate pain syndrome (toothache, migraine, headache, arthralgia, neuralgia, painful menstruation);
• febrile conditions caused by rheumatic and colds.

According to the instructions, Askofen is prescribed 1 tablet 2-3 times a day. Askofen P is recommended in a dose equal to 1-2 tablets, which should be taken three times a day after meals, accompanied by drinking plenty of fluids. The course of treatment with Askofen P usually lasts 5-7 days. To relieve acute pain, take 2 tablets once.

The instructions for Askofen P indicate diseases in which the use of this drug can harm the body:

• gastrointestinal bleeding;
• peptic ulcer of the stomach and duodenum;
• renal and hepatic failure;
• hypocoagulation;
• deficiency of glucose-6-phosphate dehydrogenase;
• portal hypertension.

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Pregnancy, breastfeeding and hypersensitivity to the components of Askofen and Askofen P are reasons for refusing to take these drugs.

This drug is recommended to be taken for severe pain of various types, including headaches and toothaches. Due to the rapid onset of the analgesic effect, Askofen is prescribed for neuralgia, arthralgia, and also in case of pain during menstruation. In addition, Askofen tablets should be taken for feverish conditions caused by colds or rheumatic diseases.

The recommended daily dosage of Askofen is one tablet several times a day. It is advisable to accompany each medication intake with plenty of fluids. The course of treatment with this drug should not exceed five days. Changes in the treatment regimen and increasing the duration of taking Askofen should be made under the supervision of the attending physician. If you do not know how to take Askofen or are unsure whether this medicine is right for you or not, consult your doctor.

Askofen

In the absence of other recommendations, Askofen can be taken 1 tablet every 4 hours. The maximum permissible daily dosage is 8 tablets. The taken tablet must be taken with a sufficient amount of liquid, preferably warm milk or boiled water. If the patient has acute pain, we can take 2 tablets at the same time. The therapeutic course averages 5-7 days.

Askofen-P

Unlike regular Askofen, the drug must be taken strictly after meals, 1-2 tablets. The frequency of administration is 3 times a day, the maximum daily dosage is 6 tablets. As a painkiller, 5-day treatment is acceptable, but if the drug is used to reduce body temperature, it should be taken for no more than 3 days.

Askofen-Extra

For adults and children over 10 years of age, the recommended single dosage is 1-2 tablets, dosage frequency 2-3 times a day. The maximum permissible daily dosage is 6 tablets. The course of therapy is directly related to the effectiveness of treatment, but most often does not exceed 1 week.

What does Askofen help with? The drug is recommended for:

• headache;
• toothache;
• myalgia of various etiologies;
• arthralgia;
• neuralgia;
• pain due to rheumatism;
• painful menstruation;
• fever that accompanies influenza and ARVI.

Due to the fact that this drug contains acetylsalicylic acid, it is able to relieve pain where the inflammatory process occurs. In addition, it thins the blood, thereby preventing the formation of blood clots.

Thanks to caffeine, askofen is a stimulant for the respiratory and vasomotor center, as it can perfectly relieve fatigue, increase performance, including mental performance, and also dilate blood vessels. But it is worth considering that these pills increase blood pressure and stimulate blood flow, which is unacceptable for many people.

Askofen copes well not only with colds, acute respiratory infections and flu, it also perfectly relieves various types of pain, including headaches and dental pain. This drug is sometimes prescribed for migraines. The effect was also obtained when using this medicine for various rheumatic diseases and neuralgia.

Particular attention should be paid to the dosage and duration of taking askofen. During a cold, the first symptoms of flu or acute respiratory infections, you need to take one tablet every four hours. To relieve pain, you need to take two tablets at a time. You should not take more than eight tablets per day. You cannot treat them for more than 10 days. Drinking alcohol during treatment is unacceptable.

Acetylsalicylic acid has a teratogenic effect; when used in the first trimester of pregnancy, it leads to a malformation - cleft palate; in the third trimester - to inhibition of labor (inhibition of prostaglandin synthesis), to closure of the ductus arteriosus in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation.

It is excreted in breast milk, which increases the risk of bleeding in the baby due to impaired platelet function.

During pregnancy and lactation

When a woman is expecting a child or is breastfeeding, she is contraindicated to use Askofen. It is indicated that only in the second trimester of pregnancy a single use of this medicine is permitted, provided that the benefit to the mother is significantly higher than the risk to the child. In the first and third trimester, using the medicine can lead to dire consequences for the child. We include here cleft palate (cleft lip, cleft palate), delayed labor and various other problems.

If a woman needs to take the drug during breastfeeding, she should stop breastfeeding. The components of the drug can pass into breast milk and harm the baby and increase the likelihood of bleeding.

The active components of the drug enhance the absorption of certain medications. These include:

• hormones that regulate vital processes (steroid);
• indirect anticoagulants;
• reserpine;
• heparin;
• hypoglycemic agents.

"Askofen" helps to weaken a number of drugs:

• "Spironolactone";
• "Furosemide";
• antihypertensive drugs and others.

Originally posted 2017-06-12 14:30:24.

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What kind of blood pressure do tablets help with?

Most doctors do not believe that the medication has a strong effect on blood pressure. But many people suffering from hypotension note a positive effect with a sharp decrease in blood pressure. It is not recommended to take Askofen tablets for high blood pressure due to the caffeine content in their composition. Askofen does not lower blood pressure and its use is contraindicated for hypertensive patients, especially regular use. The tablets can cause a hypertensive crisis.

With low blood pressure, the drug helps improve well-being, relieve headaches and dizziness, and cope with weakness and apathy. It should be drunk when the climate changes, since hypotensive people feel especially bad during this period. But the pills are classified as an emergency aid, not a drug. Therefore, it is not recommended to drink it constantly when blood pressure drops. If possible, it is better to stop taking the drug for hypotensive patients.

Instructions for use are included with the package. It lists the dosages of tablets depending on the purpose of use. Askofen for low blood pressure is not always effective, since it is not intended for use by hypotensive patients with low blood pressure. And the spectrum of its action does not cover the stabilization of low blood pressure.

Choosing the best headache pills for adults

Headache is a fairly pressing problem that requires a very serious approach. First of all, you need to find out the reason for its occurrence. The set of measures taken that will most effectively help cope with it will depend on this.

Tablets for severe headaches should be used only on the recommendation of a doctor. You should not prescribe them yourself without understanding the causes of this condition.

In some cases, even a severe headache is not a sign of a serious condition, while in others, a subtle headache can be a symptom of a serious pathological process. And independent prescription of pain therapy will lead to erasing the picture of a particular disease and, accordingly, to late diagnosis.

What pills to take for headaches

Nonsteroidal anti-inflammatory drugs. They are very widely used because they not only relieve pain, but also fight inflammation. These are the familiar aspirin, analgin, and ibuprofen. They have virtually no side effects and have little effect on the gastrointestinal tract.

Analgesics are antipyretics, a typical representative of which is paracetamol, used not only as an analgesic, but also as an antipyretic. This group also includes: aspirin, analgin, citramon, panadol, efferalgan, migrenol and many antispasmodics (spasmalgon, spasmoveralgon);

Tomatoes can offer a lot of nutrition, actually you're going to discover that this fruit will provide you with more nutrition than just about any other natural food. Obviously it is not just the nutritional facts that make this a super fruit, mainly

Antispasmodics. If you suffer from painful spasms in the head, then you should purchase antispasmodics. They are easily confused with analgesics, although they belong to a different group of drugs. Antispasmodics are used to relieve spasms and eliminate pain

Drug substitutes

The drug has several analogues. We'll tell you more about them below.

Parascophene

Parascofen is one of the many analogues of Askofen. It has a similar composition. Accordingly, its action is also aimed at reducing fever and eliminating pain. If the usual Askofen is not in your medicine cabinet, then this drug can completely replace it.

Flexen

This medicine has a more complex composition. But at the same time, its properties are similar to these tablets. Another advantage of the drug is that it is available in three different forms: capsules, suppositories and ampoules. The patient can choose the most convenient solution himself.

Artrosilene

The main component of this medicine is ketoprofen. It inhibits COX-1 and -2. Moreover, it has anti-bradykinin activity and stabilizes lysosomal membranes. Thanks to this, it has the same effect as Askofen. It is produced in the form of capsules, injection solution, gel and even spray.

The effect of Askofen on blood pressure

People often use Askofen for blood pressure. Askofen only helps people who have problems with low blood pressure. Many people prefer to use the drug during temperature changes, sudden changes in weather, or low atmospheric pressure. After taking Askofen, they note a decrease in the unpleasant manifestations of the disease, feelings of fatigue, heaviness and dizziness. Does Askofen really increase blood pressure, at what pressure should it not be taken?

Askofen tablets are used as an analgesic and antipyretic drug for toothache, headaches and to normalize blood pressure.

Askofen

Askofen is a combination drug that has an analgesic and antipyretic effect.

One Askofen tablet contains 0.2 g of acetylsalicylic acid and phenacetin, as well as 0.04 g of caffeine. Acetylsalicylic acid suppresses the synthesis of prostaglandins, which are responsible for the appearance of pain and swelling at the site of inflammation, inhibits thrombus formation and platelet aggregation. Thanks to this component, the use of Askofen allows you to relieve pain, in particular caused by inflammatory processes, and improve microcirculation in the area of ​​inflammation.

Phenacetin enhances the antipyretic and analgesic properties of acetylsalicylic acid. Caffeine, which is part of Askofen, affects the reflex excitability of the spinal cord, stimulates the vasomotor and respiratory centers, reduces platelet aggregation and dilates blood vessels. Caffeine also improves physical and mental performance, reduces fatigue and drowsiness, normalizes cerebral vascular tone and accelerates blood flow.

In Askofen P, phenacetin is replaced with paracetamol (0.2 g), which determines the anti-inflammatory, antipyretic and analgesic properties of this drug. The advantage of this component is that the likelihood of methemoglobin formation when used is minimal.

What pills can you take for headaches during pregnancy?

When prescribing a complex treatment regimen, there are always limitations. If we are talking about drug interactions of other drugs with Askofen, then the presence of its active components may disrupt the therapeutic properties of individual pharmacological groups. It is recommended to place special emphasis on the following combinations:

1. Askofen-P tablets enhance the effect of indirect anticoagulants, heparin, reserpine, hypoglycemic agents and steroids.
2. This medicine reduces the therapeutic effect of Spironolactone, antihypertensive drugs, Furosemide, and anti-gout drugs.
3. Askofen-P tablets are contraindicated in combination with barbiturates, Zidovudine, anti-epileptic drugs, Rifampicin, and alcohol.
4. Acetylsalicylic acid causes side effects of corticosteroids, NSAIDs, sulfonylurea derivatives, non-narcotic analgesics, Methotrexate.
5. Caffeine accelerates the absorption of Ergotamine, while Metoclopramide stimulates the penetration of paracetamol into the systemic circulation.

The combination of Askofen with heparin, reserpine, anticoagulants, steroid hormones and some hypoglycemic drugs enhances their effect.

When taken simultaneously with glucocorticosteroids, sulfonylurea derivatives and NSAIDs, an increase in their side effects is observed.

Combining Askofen with barbiturates, antiepileptic drugs, zidovudine and rifampicin should be avoided to avoid the development of hepatotoxicity.

Askofen promotes accelerated absorption of ergotamine.

Simultaneous use of the drug with stimulants of microsomal oxidation contributes to a negative effect on liver function.

Strengthens the effect of heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic drugs.

Co-administration with other NSAIDs and methotrexate increases the risk of side effects.

Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, as well as anti-gout drugs that promote the excretion of uric acid.

Barbiturates, rifampicin, salicylamide, antiepileptic drugs and other stimulants of microsomal oxidation contribute to the formation of toxic paracetamol metabolites that affect liver function.

Metoclopramide accelerates the absorption of paracetamol.

Under the influence of paracetamol, T1/2 of chloramphenicol increases 5 times. When taken repeatedly, paracetamol may enhance the effect of anticoagulants (dicoumarin derivatives).

The simultaneous use of paracetamol and ethanol increases the risk of developing hepatotoxic effects.

Caffeine accelerates the absorption of ergotamine.

The fastest way to deal with the problem is to take a pill. But is it possible? What can pregnant women take for headaches and what not?

Can pregnant women use Citramon?

Citramon is a combination drug for headaches that can be taken during pregnancy, but with caution. It contains Aspirin, Caffeine and Paracetamol. Caffeine is quite safe, and in cases of low blood pressure it is useful, but in order to avoid any harm from it, you need to know 100% that the cause of headaches is low blood pressure, and you can do without a pill, and use coffee or green tea.

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No-shpa

No-spa can save pregnant women not only from headaches, but also from many other pains. Unfortunately, it will not help with severe pain or migraines, but it is safe and can be taken by pregnant women, provided there are no contraindications. There are many analogues of No-shpa, the most common of which is Drotaverine.

It is better for pregnant women to choose No-shpa, although it is more expensive than its analogues, but the purification of the drug is better, and accordingly, it is more suitable for expectant mothers.

Can I have paracetamol?

Paracetamol is also a good drug for relieving mild headaches during pregnancy. It is especially good for headaches due to a cold. However, do not abuse it

What is pregnancy? This is the state of a woman's body. During this period, her body performs the function of childbirth or procreation, as you prefer.

What pills for headaches during pregnancy are recommended by experts? If taking medications usually helps to get rid of the problem, for expectant mothers their choice is very limited, since many of them can have a negative impact on the development of the fetus.

Why does a headache occur?

Experts distinguish pain by nature, intensity, and location. It can be primary or secondary. In the latter case, the pain is a consequence of some disease and is accompanied by other symptoms.

Kidney diseases, meningitis, sinusitis provoke the occurrence of severe pain. In this case, even taking medications does not help, and urgent intervention by specialists is required.

One of the reasons for the appearance of pain during the period of waiting for a child can be migraine. This disease may be accompanied by nausea and vomiting, and vision problems. According to statistics, young women are susceptible to migraines 2-3 times more than men. The headache is characterized as intense, throbbing.

eating foods that contain nitrogenous compounds (tyramine, phenylamine), which negatively affect the condition of blood vessels.

In the first months of expecting a child, women

Migraine, surges in blood pressure, osteochondrosis of the cervical spine, poor circulation in the brain - all this can trigger a headache. Analgesic drugs - headache tablets - help to alleviate the condition.

How to choose the right headache pills

Determine the intensity of pain - compressive, sharp, dull, bursting, pulling, paroxysmal or constant.

Determine the conditions under which the headache occurred - weather changes, overexertion at work, stressful situations, use of medications.

Pay attention to possible symptoms that occur with pain in the head - attacks of nausea, dizziness, tinnitus, darkening of the eyes.

Consider the patient's age - older patients are more suitable for caffeine-free tablets, while young people will benefit from this substance.

When choosing a medicine for headache discomfort, you need to remember that it can be caused by both external and internal irritants.

Pain caused by such factors does not require special treatment. Here, ordinary inexpensive headache tablets - analgesics - are sufficient.

In such cases, pain relief alone is not enough. It is necessary to undergo an examination to identify the sources of the pathological condition.

When choosing tablets for headaches, it is important to study the composition of the drug and the principle of action of the main component. It is necessary to strictly adhere to the dosage and not ignore individual contraindications.

Review of the best headache pills

On our website there is a large regular pregnancy calendar with a description of twins in each week, but we still think such a twin pregnancy calendar is necessary. Here you will find information about the nature of multiple births.

Tablets of this group are fast-acting drugs. They not only have pain relief, but also

Askofen-P: dosage, price

Beautiful-looking pale pink or cream ascophene tablets can be bought at any pharmacy without a prescription. The highest dose per day is six tablets, but it is important to take Askofen-P after meals (regardless of whether you are prescribed one or two tablets three times a day). It is advisable to drink it hot. Here are such simple instructions for using Askofen-P!

Dosages may be different: they are determined by the attending physician. For hints of a cold and headaches, one tablet is usually prescribed three times a day; for joint pain and persistent migraines, the dosage is increased. Avoid prescribing your own dosage: it is human nature to exaggerate one’s own suffering and illness, and excessive use of ascophenes leads to sad consequences. After all, the composition of Askofen-P is not so harmless; Askofen also has contraindications.

Quite precise instructions for using Askofen-P can be easily found on the Internet. It is preferable to do this on official websites . However, there is nothing complicated in the instructions for using Askofen-P: after meals, strictly in the dosage prescribed for your case by your doctor, avoiding cases where Askofen is contraindicated.

The price of Askofen-P for a package with detailed instructions for use included in it is small: a pack of ten tablets of Askofen-P can be found in almost every pharmacy for no more than 25-30 rubles. A package of twenty tablets can cost 82 rubles, and if you take into account delivery, the price of Askofen will be even more expensive. In modern times - pennies. If you order in advance, not in 24-hour pharmacies, the price of Askofen-P will not seem significant at all for any sufferer. As you can see, the price for Askofen-P may fluctuate, but within modest limits.

What to do in case of overdose

Many people are now so carried away by fashionable medicine that they forget that “everything is good in moderation.” The composition of Askofen-P is not so harmless: do not forget about the caffeine included in Askofen-P! And this component of Askofen-P has quite serious contraindications and makes the composition of Askofen-P not so harmless. Meanwhile, with excessive use of any ascophenic drugs, an overdose is possible with very sad consequences.

So, if you are taking Askofen and suddenly begin to feel ringing in the ears, tachycardia or sudden convulsions, then do not delay: rinse your stomach (it is better to have paramedics do this), eat activated charcoal. Because these are symptoms of just mild intoxication, with a serious overdose, if you do not take action, respiratory paralysis and collapse with anuria await you. Therefore, Askofen during pregnancy can even cause death.

Isn’t the “savior from all pains and colds” very reliable, Askofen? However, who in their right mind would swallow more than ten tablets a day? Treat yourself as prescribed in the instructions for use of Askofnea-P, remember the contraindications, and you will forget about pain and colds!

The drug Askofen

Contraindications to the use of Askofen

The instructions for Askofen P indicate diseases in which the use of this drug can harm the body:

• gastrointestinal bleeding;
• peptic ulcer of the stomach and duodenum;
• renal and hepatic failure;
• hypocoagulation;
• deficiency of glucose-6-phosphate dehydrogenase;
• portal hypertension.

Pregnancy, breastfeeding and hypersensitivity to the components of Askofen and Askofen P are reasons for refusing to take these drugs.

The shelf life of Askofen is 4 years, Askofen P is 3 years. These drugs should be stored in a dry and dark place, at a temperature not exceeding 25 0 C.

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

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Askofen-P - has analgesic, antipyretic and anti-inflammatory effects

Askofen-P, an anesthetic with an optimal* combination of three active components, can help cope with pain. Askofen-P is a gentle, time-tested product at an affordable price**

The analgesic effect is achieved through a combination of three main active ingredients: paracetamol, acetylsalicylic acid and caffeine.

Acetylsalicylic acid in Askofen-P has an analgesic, antipyretic and anti-inflammatory effect. It is associated with the suppression of the enzyme cyclooxygenase types 1 and 2, which regulates the synthesis of prostaglandins - mediators of pain and inflammation.

Paracetamol is an analgesic with analgesic and antipyretic effects, which are achieved by the drug’s effect on pain centers and thermoregulation in the brain. Paracetamol has a well-studied mechanism of action and safety profile.

Caffeine is an active component that has a stimulating effect on the respiratory and vasomotor centers of the brain and helps relieve fatigue and increase mental and physical performance. Caffeine acts as an auxiliary component which, according to studies, can enhance the analgesic effect of paracetamol and acetylsalicylic acid.

Thanks to these components, the drug Askofen-P® helps relieve common pain syndromes caused by neurological and inflammatory diseases, as well as muscle, headache, joint and toothache.

Indications for use

In adults and children (over 15 years of age) as an anesthetic for mild to moderate pain:

• headache
• migraine
• toothache
• muscle and joint pain
• neuralgia
• algomenorrhea

In adults, it can be used for ARVI and influenza as an antipyretic.

Askofen-P® is a time-tested and affordable** analgesic that has been trusted for over 20 years.

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