Hexoral rinse solution: composition, indications, instructions for use

Release form and composition

The drug is available in the following dosage forms:

• Aerosol for topical use 0.2% (sometimes mistakenly called a spray).
• Lozenges Geksoral tabs.
• Solution for topical use 0.1%. The composition of the medicine in the form of a solution includes the active component hexethidine (100 mg).

Hexoral spray is contained in a 40 ml aluminum bottle. The cardboard pack contains one bottle of solution, a spray nozzle and instructions for using the drug.

The composition of the medicine in the form of an aerosol includes the active component hexetidine (200 mg), as well as additional components: polysorbate 80, citric acid monohydrate, levomenthol, sodium saccharinate, sodium calcium edetate, eucalyptus leaf oil, sodium hydroxide, water.

Geksoral's analogs

Analogues by mechanism of action include the drugs Tantum-Verde, Ingalipt, Stopangin, Lizobakt and Miramistin.

Plisov Vladimir, doctor, medical observer

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Indications for use

What does Hexoral help with? Spray and solution are used in the following cases:

• for periodontopathies;
• to ensure additional oral hygiene for common diseases;
• for gingivitis and bleeding gums;
• in case of infection of the alveoli after the tooth has been removed;
• for infectious inflammatory diseases of the pharynx and oral cavity;
• with sore throat;
• with tonsillitis;
• to eliminate bad breath, in particular in people with disintegrating tumors of the pharynx and oral cavity;
• with pharyngitis;
• in the period before and after operations of the pharynx and oral cavity;
• for candidal stomatitis, as well as a number of other fungal infections of the pharynx and oral cavity;
• in the complex treatment of severe febrile or purulent diseases of the pharynx and oral cavity and pharynx, for which antibiotics and sulfonamides are prescribed;
• for aphthous ulcers, glossitis, stomatitis, as well as for the prevention of superinfections;
• as an auxiliary drug in the treatment of colds.

When is Hexoral prescribed?

Indications include the following diseases:

• acute bacterial and viral infections of the upper respiratory system (unspecified);
• pharyngitis;
• tonsillitis;
• oral candidiasis;
• gingivitis (inflammation of the gums);
• periodontitis (damage to periodontal tissue);
• aphthous stomatitis;
• glossitis;
• alveolitis (inflammation of the tooth sockets).

Important
After tooth extraction surgery, it is advisable to apply the solution into the hole to prevent the development of the inflammatory process.

Pediatricians recommend using Hexoral for prevention at the first signs of colds.

Instructions for use

Hexoral is applied topically. When using an aerosol for topical use in adults and children over 3 years of age, a single dose is administered over 1-2 seconds. When using a solution for topical use, rinse the mouth and throat with 15 ml of undiluted solution for 30 seconds.

The drug is prescribed 2 times a day (preferably in the morning and evening), after meals. Safe with more frequent use. Hexethidine adheres to the mucous membrane and due to this gives a lasting effect. In this regard, the drug should be used after meals. The duration of treatment is determined by the doctor.

Rules for using the drug

When using a topical aerosol, the drug is sprayed into the mouth or throat. Using an aerosol you can easily and quickly treat the affected areas. You need to do the following:

1. Place the aerosol tube in the corresponding hole in the upper part of the bottle, lightly pressing on it, and point the tip of the tube away from you.
2. Hold the aerosol tube and direct it to the affected area of ​​the mouth or pharynx.
3. During administration, the bottle should be kept in an upright position at all times.
4. Inject the required amount of the drug by pressing on the head for 1-2 s, do not breathe while administering the aerosol.

The topical solution can only be used to rinse the mouth and throat. The solution should not be swallowed. When rinsing, you should always use an undiluted solution. When treating diseases of the oral cavity, the solution can also be applied using a tampon.

Pills

The tablet should be slowly dissolved in the mouth until completely dissolved. The drug should be started immediately after the first symptoms of the disease appear and continued for several days after the symptoms disappear.

Adults and children over 12 years of age are prescribed 1 tablet every 1-2 hours as needed, but not more than 8 tablets per day. Children aged 4-12 years are prescribed up to 4 tablets per day.

Mechanism of action

Hexoral has analgesic, antiseptic, antifungal, and hemostatic properties. The antiseptic effect is due to the blockade of oxidative reactions of microorganisms. The solution is highly active against a wide range of bacteria and fungi of the genus Candida. It is very effective against pathogens of the genus Proteus and a number of viruses. Successfully suppressing most strains of bacteria, Hexoral does not provoke the development of resistance in them.

Its biologically active component hexethidine is almost not absorbed, remaining in the oral cavity for a long time. On dental plaques, active concentrations of the antibacterial component are detected within 14 hours after a single application.

When hexethidine comes into contact with the mucous membranes of the mouth, it has an anesthetic effect.

Children, pregnancy and breastfeeding

It should be borne in mind that this drug can be prescribed to children after reaching three years of age. The instructions for children inform that the use of the solution is possible at an age when the child is able to consciously rinse the mouth and throat, and there is no danger of swallowing the liquid.

Hexoral spray is also not used for children under 3 years of age. It is important that the child does not resist the spray nozzle in the mouth and can hold his breath while the drug is injected.

For children over 3 years of age, the product is used in the dosage indicated in the instructions.

There is no data on any damaging effects of the drug Hexoral during pregnancy and lactation. However, before prescribing a medication to pregnant or lactating women, the doctor must carefully weigh the benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placental barrier and into breast milk.

Contraindications

Hexoral is a medicine for external use. Its active substance adheres to the mucous membrane, without penetrating into the tissue, and is practically not absorbed into the bloodstream. Therefore, the spray is not contraindicated for pregnant and lactating women.

The product should not be used by patients with hypersensitivity to the components of the drug and children under three years of age. A small child does not know how to hold his breath while injecting an aerosol. As a result, fine particles can enter the mucous membrane of the lower respiratory tract, which can lead to spasm of the trachea and/or larynx. With laryngospasm, breathing becomes difficult and sometimes stops altogether.

However, the answer to the question at what age can Hexoral be used to treat children is not always so clear-cut. Provided that laryngospasm is completely excluded, the pediatrician can prescribe the spray even for a child under one year old.

Hexoral is not absorbed into the bloodstream and is absolutely safe. The main thing is that its fine particles do not get on the tissues of the lower respiratory tract during an accidental inhalation. And for this, it is enough for the child to not breathe for about three seconds and calmly react to the introduction of a spray nozzle into the mouth.

special instructions

Before you start using the drug, you must carefully read the instructions for it; there are several special instructions that are important to consider:

It is better to spray after eating, after rinsing your mouth with water; after treating the oral cavity, it is advisable not to eat or drink for an hour. Care should be taken not to swallow the aerosol while spraying. It is not recommended to drink alcohol during treatment.

Long-term use of Hexoral spray is not recommended, as this can lead to disruption of the functioning of taste buds and the development of dysbiosis (death of bacteria representing normal microflora with the subsequent development of opportunistic microorganisms).

Hexoral spray does not affect the speed of psychomotor reactions and concentration, however, it is worth considering that this is an alcohol-containing drug, so if a large amount of the aerosol is used or it gets into the stomach, the effect of mild intoxication may develop.

Side effects

In extremely rare cases, allergic reactions to the drug (shortness of breath, urticaria, angioedema) were recorded. Prolonged uncontrolled use (self-medication) can cause changes in taste sensations. Dysphagia and nausea are extremely rare.

Vacation conditions and price

The average cost of Hexoral (40 ml aerosol) in Moscow is 307 rubles. The price of Hexoral Tabs tablets is 174 rubles for 20 pieces. The drug is available in the pharmacy chain without a prescription. If you have any questions or doubts regarding its use, you should consult your doctor.

The shelf life of the drug is 2 years from the date of manufacture. The spray must be stored out of the reach of children at a temperature not exceeding +25 C; it should not be allowed to freeze. Hexoral in aerosol form can be used for 6 months after the first use.

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Description of the drug, composition

Produced by German and Indian pharmaceutical companies.

Hexoral lozenges are available in blisters, packed in cardboard boxes. Each contains two blisters. The shape of the tablets is round, convex on both sides. Not white. They may be yellowish-gray or yellowish-white, slightly rough to the touch. The drug consists of two main active ingredients that complement each other well: chlorhexidine dihydrochloride (5 mg) and benzocaine (1.5 mg). Exactly how much substance is in one tablet. In addition, there are auxiliary ingredients, including mint oil, menthol, thymol, aspartame, isomalt and distilled water. They have different tastes, so they are well received by children. Thanks to flavorings and sweeteners, they can be in the following flavors:

• Orange;
• Lemon;
• Honey-lemon;
• Black currants.

Hexoral is available without a prescription. There are cheaper analogues, but their effectiveness in the treatment of diseases of the oropharynx is much lower.

Which is better: Hexoral or Stopangin

When choosing similar drugs for angina, Hexoral and Stopangin are often compared. There is no fundamental difference between the drugs.

Similarities:

1. Same active ingredient
2. Same indications for use
3. Almost the same cost

Differences:

• Stopangin contains a larger amount of essential oils, which can cause side effects
• Stopangin is contraindicated in the first trimester of pregnancy

Reviews from doctors clearly indicate the benefits of the drug Hexoral. It is safe for patients of different ages and physical conditions. When choosing a method of treating a sore throat, it is better to listen to the recommendations of a specialist.

Use in children

It is recommended not to use Hexoral for children under one year of age. According to the instructions, this is due to the fact that in order to use the spray, the child must be able to hold his breath and calmly respond to the insertion of the nozzle into the oral cavity.

When used in children, the following sequence of actions should be followed:

• The child should be explained the essence of the procedure and the need to hold his breath. You can show how to do this correctly using your own example. This way it will be clearer for the child.
• Ask him to open his mouth, but his tongue should not cover his throat.
• The bottle is held vertically with the bottom down.
• There is no need to insert the nozzle deeply, as the spray is sprayed 5-8 cm.
• Tell your child to hold his breath.
• Press the nozzle for 1 second.
• Remove the nozzle from your mouth.

The aerosol has a menthol aftertaste. It does not cause negative reactions in children.

Reviews

• Anastasia, 26 years old : “Our doctor recommended Hexoral spray to us when my daughter had a sore throat. This disease was very difficult for us. Thanks to therapy with Hexoral, my daughter felt better within 3-1 days. She stopped crying, the swelling went away, only a slight redness remained, and after a few days this also disappeared. There were no side effects and we are very pleased with the result.”
• Tatyana, 35 years old: “I heard a lot about the effectiveness of Hexoral spray that I decided to try it for my daughter, who was diagnosed with tonsillitis. We carried out the therapy, as indicated in the instructions, for 5 days, after which I did not observe any positive effects. I had to go to the clinic to prescribe complex treatment.”
• Tatyana, 28 years old: “I used the drug for my son when he was 2.8 years old. Although the instructions prohibit the use of Hexoral for children under 3 years of age, I consulted with a doctor and he gave the go-ahead for such treatment. The positive effect was noticeable on the 2nd day. My child began to feel better, his temperature subsided, and his appetite improved. As for side effects, there were none, so the drug can be used by young patients, but in some cases and only with the permission of a doctor.”

Hexoral spray is a very effective medicine in the treatment of viral diseases in children. Thanks to its unique composition, it causes virtually no side effects. But therapy with Hexoral should not last more than 5 days. In the absence of positive dynamics, it is necessary to apply more effective treatment.

How to carry out lubrication?

Instructions for lubrication with Hexoral:

1. It is necessary to pour a certain amount of the drug into a spoon.
2. Take a cotton swab or tweezers and some cotton wool.
3. Dip cotton wool into the solution.
4. Lubricate the oral mucosa, not only the affected areas, but also the gums, the area under the tongue, the root of the tongue, and the tongue.
5. Periodically moistening the cotton wool, you should completely treat the entire oral cavity.

As after rinsing, after lubrication it is important to refrain from drinks and food.

Using the solution may cause a slight burning sensation, so before the procedure you should explain to the child that unusual sensations may appear in the mouth.

Composition and form of Hexoral in solution

The main substance of the solution is hexethidine (0.1%).

Hexetidine is an antiseptic and antifungal agent that destroys the membrane of bacteria and fungi, which leads to their death.

Additional components of Hexoral solution:

• Alcohol (3.83 vol.%);
• oils - mint, anise, cloves, eucalyptus;
• anesthetics;
• lemon acid;
• sweetener;
• food coloring;
• preservative;
• water.

The solution is red in color and transparent to light. The smell is minty. The taste is specific, due to citric acid, sweetener, plant components and levomenthol.

The solution is available in 200 ml bottles. One bottle is designed for 6 days of treatment, subject to the dosage and frequency of use specified in the instructions.

Overdose

According to the instructions, it is unlikely that hexethidine has a toxic effect when taken in recommended doses. If the drug is accidentally swallowed, symptoms of alcohol intoxication may appear. Treatment is gastric lavage within two hours after the child swallows the dose, symptomatic therapy. In any case of overdose, the patient should see a doctor.

An overdose of tablets is unlikely; its symptoms are suffocation, tremors of the limbs, vomiting, and convulsions. Respiratory depression can cause coma and death. Treatment consists of artificially inducing vomiting and gastric lavage with activated charcoal. For convulsions, barbiturates or diazepam are prescribed, for hypoxia - artificial respiration and suxamethonium chloride, circulatory support by administering electrolyte solutions.

"HEXORAL tabs" (lozenges): instructions

The permissible dosage is determined depending on the medical history and age category of the patient:

1. The maximum daily dosage for children aged 4 to 12 years is 4 tablets.
2. Teenagers over 12 years old and adults – 8 tablets.

Cases of drug overdose are unlikely due to the lack of absorption of chlorhexidine and the minimal content of benzocaine. In rare cases, due to direct contact of gluconate with chlorhexidine, mucosal damage and increased liver enzyme levels may occur.

An overdose of benzocaine provokes tremor, vomiting, convulsions, bradycardia, and in children - methemoglobinemia in the form of suffocation and cyanosis.

If symptoms of overdose occur, seek emergency medical help immediately.

With great caution and without fail under the supervision of the attending physician, it is allowed to take the medicine if there are erosive and desquamative formations on the oral mucosa.

How to take it correctly?

Take when the first symptoms of inflammation and pain appear for 3-7 days until they disappear:

1. the intake can be carried out regardless of meals;
2. put the tablet in your mouth under your tongue;
3. dissolve the pill until it completely dissolves;
4. to obtain the desired result, the reception can be repeated after one or two hours;

How to replace Hexoral

Is it possible to replace Hexoral?

Lollipops with a similar composition can be selected without much difficulty. And, with regards to the spray and solution for gargling, in this case hexethidine-containing ones are suitable:

An equally good effect can also be achieved using any type of drug.

Which is better for Hexoral or Tantum Verde?

The selection of drugs is an individual and painstaking procedure, in which it is necessary to take into account many circumstances and features. Therefore, it is impossible to unequivocally state in this case that one of the drugs is more successful than the other. Each of them is in demand and has positive reviews.

It is better to contact your personal physician or otolaryngologist with this question, who will evaluate the benefits of the proposed drugs and select the ideal one for the current characteristic situation.

Gargling Solution

Another form of release of Hexoral is a solution that is used to gargle. 1 ml of solution contains equivalent to 1 ml of the active substance - Hexatedin and ethanol, which is why, if you have a driver's license and tonsillitis, it is better to get behind the wheel half an hour after the rinsing session. For the same reason, the solution is not used to treat children under 7 years of age.

Dosage

Rinse the mouth and throat with an undiluted solution; 15 ml is enough for one procedure. Rinsing should last at least half a minute and be done twice or thrice a day.

Despite the fact that, theoretically, gargling a child’s throat is allowed from the age when the baby can perform these actions, in the case of Hexoral, the main danger lies in the possible ingestion of the medicinal liquid.

It should be borne in mind that swallowing the solution is strictly prohibited. But, if this happens, you should increase the amount of liquid you drink and take the enveloping enterosorbent Atoxil or Enterosgel.

How to gargle?

To correctly carry out the rinsing procedure with Hexoral is to follow these steps:

Negative Impacts

Is it possible to use Hexoral rinse solution during pregnancy?

When using a medicinal solution, various negative effects may occur, including:

1. Angioedema, urticaria and other hypersensitivity reactions of the immune system.
2. Dysgeusia, ageusia – from the nervous system.
3. Shortness of breath, cough caused by allergic manifestations - from the respiratory system.
4. Vomiting, increased size of the salivary glands, nausea, dysphagia, dry mucous membranes in the oral cavity - from the gastrointestinal tract.
5. Ulcerations, blisters, inflammation, discoloration of tooth enamel, tongue, paresthesia of the oral cavity, burning, irritation reaction on the mucous membranes of the pharynx and oral cavity at the site of application.

If these negative symptoms are detected, it is important to consult with a specialist about discontinuing the drug or replacing it with an analogue.

The instructions for use for the Hexoral rinse solution must be strictly followed.

Analogs

When choosing similar drugs for angina, you need to be careful about the composition of the drug, the spectrum of action and possible contraindications. It is better if the choice is made in a medical institution after the necessary tests have been carried out.

The best analogues:

1. Tantum Verde is a medicine whose range of action is very similar to Hexoral. The active ingredient is different. Contraindicated for children under 3 years of age and pregnant women. When used correctly, it does not cause a negative reaction in the human body.
2. Ingalipt is a cheaper analogue of Hexoral. Belongs to two groups: sulfonamides and antiseptics. Due to the smaller composition of components, it can relieve fewer diseases.
3. Miramistin - according to reviews, the best remedy against inflammation of the mucous surfaces of the nasal and oral cavities. It is tasteless and odorless and does not contain essential oils. When choosing Hexoral or Miramistin to prescribe for a pregnant woman with sore throat, preference is always given to the second drug. Available in the form of a solution with a spray cap.
4. Lizobakt - produced in the form of dragees for resorption. Effective for treating sore throat and sore throat due to sore throat. Not suitable for use by children under 3 years of age. Able to enhance the effect of drugs during joint therapy.

Hexoral price

The cost of Hexoral depends on the form of release, the manufacturer and the price category of the pharmacy. Prices on the Internet are cheaper than in traditional pharmacies, but you will have to pay for delivery. Approximate prices for medicine:

Other types of Hexoral

Hexoral spray

Aerosol Hexoral is similar to the product in liquid form. It is the drug of choice for bacterial inflammation and fungal infections of the throat.

Fine spray and an elongated spray tube allow you to deliver the medicine directly to the mucous membrane of the pharynx and tonsils.

The sprayed drug remains on the mucous membrane for up to 12 hours, during which it retains its activity against fungi and bacteria.

Hexoral tablets

The tablet form of Hexoral differs in composition:

• Chlorhexidine (antiseptic);
• benzocaine (anesthetic).

The analgesic effect of Hexoral Tabs is more pronounced than that of the solution, but does not last long.

In addition to Hexoral Tabs, you can find close analogues in pharmacies:

• Hexoral Tabs Classic;
• Hexoral Tabs Extra.

Despite the use of the trade name Hexoral, these lozenges contain other active substances. Hexoral Tabs Classic and Extra are not intended for use by children under 6 and 12 years of age, respectively.

"GEXORAL tabs": reviews

I would like to leave a positive review about Hexoral tablets. I always suffer with my throat, especially in the off-season. As soon as my throat starts to feel sore, I immediately start taking it. The most important thing for me is that it helps, and it does. Pleasant to the taste, relieves a sore throat from the very first minute, reasonable price for 20 tablets, plus they are available without a prescription, which means they are available at any time and in any pharmacy.

In our climate, colds are a common occurrence. I suffer from a sore throat very often, so at the first symptoms I immediately start taking something. I buy Hexoral because, firstly, they are quite effective, quickly and permanently relieve a sore throat, have a pleasant taste and are convenient to take with you, and secondly, they are quite inexpensive. I generally take about 6 pieces per day, and after three days the sore throat gradually goes away and doesn’t bother me anymore. I recommend it.

Indications and contraindications for the use of the drug for the throat

Hexoral is used for the following diseases of the nasopharynx:

1. Pharyngitis is an inflammation of the mucous and lymphoid tissue of the pharynx. Accompanied by sore throat. The disease can occur in two forms: acute and chronic.
2. Sore throat is an acute infectious disease characterized by inflammation of the palatine tonsils.
3. Gingivitis is inflammation of the gum mucosa. Occurs due to unhygienic maintenance of the oral cavity. And also as a result of a general disease. Characterized by hyperemia and bleeding gums.
4. Stomatitis is an inflammatory process of the oral mucosa.
5. Sinusitis is an inflammation of the mucous membrane, and in some cases, the bone walls of the maxillary sinus.
6. Otitis is an inflammation of the middle ear. Accompanied by pain and fever.
7. An adjuvant in the treatment of influenza, ARVI.

Hexoral lozenges are most effective at the first manifestations of the disease. There is no need to stop taking them until complete recovery.

In total, you will need eight lozenges per day. This is the optimal norm for acute disease. At the initial stage, the tablet should be dissolved every two hours. Just suck it like candy. Do not gnaw, chew or swallow, but dissolve. After use, try not to drink or eat for an hour. It is not recommended to use Hexoral in smaller doses, since in this case harmful microorganisms will simply get used to the constituent components and adapt to them.

Contraindications to the use of the drug:

• Sores and ulcers in the mouth;
• Allergy to the constituent components of the drug;
• People who suffer from swallowing disorders are at risk. They should not be given lozenges;
• Children under four years of age;
• Side effects include: cough, tearing, numbness in the mouth. Dyes may also cause the tongue or filling to become stained for a short time.

During pregnancy

How Hexoral affects the body of the mother and unborn child has not been thoroughly studied. In some cases, if necessary, you can use this medicine - no more than four tablets per day and no more than one per appointment.

The components of the component and their breakdown products can pass through the placenta and into breast milk.

Instructions for the use of Hexoral lozenges for young children

The use of the drug and its dose differ from the norms prescribed for adult patients:

• Children from four years old can dissolve one lozenge four times a day;
• This drug is not recommended for children under four years of age for the following reasons:
• The drug contains allergens. Since in young children the immunity is not yet fully formed, and in some cases the resorption of lozenges is weakened, it can lead to the development of allergies;
• Most children may have increased sensitivity to the constituent components of Hexoral;
• Chlorhexidine and benzocaine are somewhat toxic when they enter the esophagus. The child can simply swallow the lozenge without swallowing it;
• They can cause deterioration in oxygen transport in the baby’s body.

The child should dissolve the lozenge only under parental supervision.