Detralex tablets in the treatment and prevention of varicose veins

Causes of circulatory disorders

Unfortunately, poor circulation and congestion in the venous system are caused by a variety of circumstances:

• Sedentary work and physical inactivity;
• On your feet all day;
• Excess weight;
• Pregnancy;
• Taking oral contraceptives;
• Uncomfortable tight shoes and clothes;
• Smoking and alcohol abuse;
• Hereditary weakness of venous valves.

Among the various pharmaceutical and folk remedies that help preserve the beauty, health and youth of ever-working legs, a special place is occupied by medicines that protect and tonify the blood outflow system from the lower extremities, namely the venous system. The most prominent representative of this group is Detralex.

Is the treatment of varicose veins with tablets effective?

Varicose veins are one of the most common ailments that plague the fair half of humanity. It is women who are more susceptible to this pathology.

Pharmaceutical companies offer a large number of various products to eliminate varicose veins: creams, gels, special compression garments, elastic bandages. However, experts assure that tablets provide the greatest benefit.

How does a tablet (phlebotonic) designed to get rid of varicose veins work? Unlike creams and gels, which have difficulty reaching the affected veins through the skin, tablets act from the inside directly at the root of the problem.

Phlebotonics have the following effects:

1. Increases venous tone.
2. Strengthen and compact the walls of blood vessels, capillaries, and veins.
3. Prevents the union of red blood cells and platelets.
4. Reduce the permeability of the walls of blood vessels and veins.
5. Spider veins and spider veins are reduced or completely eliminated.
6. Relieves inflammation.
7. Allows you to get rid of swelling, pain and heaviness in the legs.
8. Normalize blood circulation.
9. Eliminate stagnant processes.
10. Prevents the formation of blood clots.

It is extremely important to remember - self-medication is unacceptable! The drug must be prescribed by a phlebologist and taken according to the instructions for use!

Medicinal properties of Detralex, forms, indications and restrictions

Detralex is a drug of French origin. During its production, all active ingredients are well purified, so the drug has a therapeutic effect very quickly. Detralex belongs to the group of venotonics. During treatment with the drug, the following effects are observed. In patients, the resistance of the capillary bed to damage increases. The medicine helps reduce the stretching of venous vessels and increases the permeability of capillary walls.

The effectiveness of the medicine increases depending on the prescribed dosage. The optimal dosage is 1000 mg per day. During therapy, patients experience relief from symptoms of varicose veins in the legs, and the course of varicose veins in the pelvis is alleviated. In patients with hemorrhoids, symptoms become less severe. With varicose veins of the lower extremities, heaviness in the legs goes away and ulcers disappear. The effect of treatment is increased if Detralex is used in conjunction with compression therapy.

Detralex is produced in tablet forms. Tablets may contain 500 and 1000 mg. The active components of the drug are flavonoid fractions (diosmin, hesperidin).

Detralex has its indications and limitations.

While using the medicine, adverse reactions may occur.

Undesirable manifestations of Detralex:

• headache;
• dyspepsia;
• allergic reactions (rash, itching, urticaria, Quincke's edema).

If undesirable manifestations occur, you should discontinue the drug and consult a doctor.

The effect of the drug has not been fully studied, so it is not prescribed during breastfeeding and for children under 18 years of age. Detarlex is used in pregnant women for the prevention and treatment of varicose veins of the lower extremities, as well as the pelvis. You can use the drug for hemorrhoids.

Detralex analogues for hemorrhoids list with prices

List of analogues for hemorrhoids:

1. Phlebaven is a Russian-made drug used for acute hemorrhoids, as well as venous insufficiency in general. The product allows you to successfully cope with swelling, inflammation, and pain. Side effects occur extremely rarely. In case of overdose, dizziness, stomach upset, headache and nausea, as well as a mild allergic reaction on the skin may occur. The price for 64 tablets is 850 rubles.
2. Venarus is a Russian remedy used for acute and chronic forms of hemorrhoids, as well as painful cramps in the limbs. As a result of taking it, negative symptoms may appear: headache, diarrhea, nausea, weakness, pain in the chest and abdomen, allergic reaction. The cost for 50 tablets is 570 rubles.
3. Venosmin is a Ukrainian-made drug whose action is aimed at eliminating venous stagnation, improving vascular tone and normalizing lymphatic drainage. The active substances are diosmin and hesperidin. The medication is effective in the treatment of hemorrhoidal disease in acute and chronic forms. It exhibits maximum effectiveness in the initial stages of disease development. At the same time, swelling and pain in the lower extremities, as well as spider veins, go away. The price, depending on the dosage and number of tablets, varies from 300 to 1000 rubles.
4. Anavenol is a Ukrainian product containing natural ingredients of plant origin. Allows you to eliminate the inflammatory process and reduce swelling, as well as improve blood circulation in peripheral vessels. Approved for use in the second trimester of pregnancy. The price is about 220 rubles.
5. Normoven is a Ukrainian-made drug used for chronic hemorrhoids, as well as chronic venolymphatic insufficiency of the lower extremities. A contraindication to its use is the period of breastfeeding. The price ranges from 400 to 600 rubles.
6. Troxevasin is a Bulgarian-made product, produced in capsules. It is prescribed for the treatment of venous insufficiency of any kind, edema of the lower extremities, thrombophlebitis and periphlebitis, as well as hemorrhoidal disease. In addition, the medication is very effective in the treatment of injuries and bruises characterized by the occurrence of hematomas. It is not recommended for use in cases of severe kidney pathologies, stomach and duodenal ulcers, chronic gastritis and early pregnancy. The cost for 50 capsules is 400 rubles.
7. Venozol is a Russian-made dietary supplement. The main indications include varicose veins, swelling of the lower extremities and night cramps, cyanotic venous network in the legs, hemorrhoids. The drug is also used in preparation for surgery to treat varicose veins in the pelvic area. This allows you to restore the outflow of venous blood from the skull. The cost for 36 tablets is 340 rubles.
8. Troxerutin is a Russian drug used to treat chronic venous insufficiency, varicose veins, thrombosis of the veins of the lower extremities, periphlebitis, postthrombic syndrome, acute and chronic hemorrhoids, edema, and hematomas. The cost for thirty capsules is 210 rubles.

Detralex's analogs

Full analogues (generics) of Detralex that are cheaper than the original drug:

1. Venozol (Venozolum) is a drug with the main active ingredients - diosmin and hesperedin. Pharmacological action is similar to Detralex. Release form: tablets, gel and cream. Price 300 rubles.
2. Venarus is a generic drug with the same active ingredients (diosmin and hesperidin). The principle of action is the same as that of Detralex. Release form: coated tablets. Price 450 rubles.

Incomplete analogues of Detralex that are at the same level as the original:

1. Phlebodia 600 (Phlebodia 600) – available in tablet form. The active ingredient, diosmin, has a medicinal effect similar to Detralex (increases the tone of the venous wall, improves blood flow, normalizes the permeability of vascular walls). Price 900 rubles.
2. Vasocet is available in the form of oblong yellow tablets. The active substance (diosmin) reduces the distensibility and increases the tone of the veins, thereby preventing the appearance of edema. Price 800 rubles.

Before using analogues, consult your doctor.

Mechanism of action of the drug

Detralex is a complex drug. It contains two active ingredients at once - diosmin and hesperidin, which complement each other well.

Diosmin is a bioflavonoid, and has many beneficial properties for venous insufficiency, namely:

• increases the tone of the venous wall;
• improves lymphatic drainage;
• reduces the crowding of leukocytes;
• improves microcirculation in peripheral tissues;
• prevents the production of thromboxane, a blood clotting factor;
• blocks the synthesis of inflammatory activators – prostaglandins;
• prevents lipid peroxidation;
• prevents the formation of free radicals.

Hesperidin belongs to natural bioflavonoids-rutinosides, which are associated with rutin (vitamin P), due to which the drug:

• is a powerful antioxidant;
• stimulates the production of collagen, a substance that is part of the vascular walls;
• reduces the permeability of vascular walls;
• improves microcirculation in tissues;
• has antiallergic properties;
• reduces tissue swelling;
• protects other bioflavonoids from free radicals.

Hesperidin is found in large quantities in the white part of the peel of sweet citrus fruits (tangerines, oranges, pomelo, grapefruits) and in some medicinal plants, in particular valerian and bomeria (a type of nettle).

Obviously, the tandem of diosmin (450 mg) and hesperidin (50 mg) is a win-win in the prevention and treatment of varicose veins and other vascular disorders. Therefore, the indications for use of the drug Detralex are:

• disturbances of venous blood flow in the lower extremities, which manifests itself in the form of tired legs syndrome, swelling, pain in the leg muscles;
• varicose veins of any location (lower limbs, genitals, hemorrhoidal veins, esophageal veins);
• tissue pastiness due to increased permeability of vascular walls;
• impaired lymphatic drainage.

https://youtube.com/watch?v=14avkkaxVSA

Doctors' opinion about the drug 1000 mg and 500 mg

The treating doctors decide which Detralex is best after assessing the condition of the blood vessels and the clinical picture of the disease. It is preferable to treat chronic pathologies with mild symptoms with the drug 500 mg. In the acute form, at the beginning of the course you need a “shock” dosage - 1000 mg tablets or 1000 mg/10 ml suspension taken 2-3 times a day. As the process fades, the patient can be transferred to another treatment regimen: using the table. 500 mg 1-2 times/day.

With a properly selected treatment regimen, there is no difference in effectiveness between Detralex 500 mg and 1000 mg. But for many patients, taking 1000 mg tablets causes side effects, and 500 mg tablets are not effective enough. Therefore, the drug is replaced with phlebotonics with a different dosage, for example, Phlebodia 600 mg, containing only diosmin.

Detralex or Venarus for hemorrhoids, which is better?

Venarus is a complete structural analogue of Detralex, which suggests a similar effect of both drugs. Thanks to the special technology used in the preparation of the original French remedy, it is absorbed within hours and begins to act much faster. It is micronization that promotes its use in acute hemorrhoids. In this case, the pain syndrome disappears within ten hours from the moment of administration.

Taking Detralex does not cause problems with concentration and attention

The effect of Venarus is also pronounced in the long term, but it is ineffective for pain syndrome. The reduction in unpleasant symptoms occurs gradually and is minimized only by the twentieth day from the start of use. In addition, problems with concentration and increased drowsiness may occur.

Therefore, Venarus is best used as maintenance therapy during remission; in the acute phase, when pain should be quickly relieved, you should pay attention to the French original

International quality standard 5

The quality management system covers all stages and aspects of the production of Detralex and guarantees strict compliance with strict corporate standards and the requirements of the international GMP standard

All apply international GMP standards (translated as good manufacturing practice). These are certain rules for the production of high-quality medicines, including requirements to strictly control the condition of the starting materials and all components of the future drug.

and the norms of Russian legislation.

Quality control is carried out at all stages of drug production: at the stage of ingredient control, during each production operation and at the stage of finished product release.

Thanks to uniform requirements for the quality of the drug, Detralex, produced in Russia, is completely identical in terms of effectiveness and safety to Detralex, which is produced in other countries (in France the drug is called Daflon, and in Canada - Venixxa).

All about the drug Detralex

It is a venotonic drug and also has an angioprotective effect. The composition is a duet of two powerful substances, diosmin and hesperidin.

1. Symptoms of varicose veins.
2. Venous insufficiency.
3. Discomfort in the legs (pain, heaviness, swelling, cramps).
4. Trophic disorders.
5. Hemorrhoids at any stage (including the period of exacerbation).

As for contraindications, this drug is completely safe for the body. It is not recommended for use only in case of individual hypersensitivity to the components of the drug. During breastfeeding, it is prescribed solely at the discretion of the doctor!

Side effects

Possible side effects:

• headache;
• dizziness;
• nausea;
• urge to vomit;
• bowel dysfunction (in most cases - diarrhea, much less often - constipation);
• general malaise;
• swelling;
• development of an allergic reaction.

The drug should be stored in a dark place, at a temperature not exceeding 25°. Shelf life – 4 years from the date of manufacture.

The cost depends on the number of tablets in the package and the content of the active substance. So, how many tablets are there in a Detralex package? The French pharmacological company produces the drug in 30 and 60 tablets. Approximate cost in Russian pharmacies:

• 30 pieces of 500 mg – price ranges from 750-1000 rubles;
• 60 tablets of 500 mg - costs about 1450-1600 rubles;
• 30 pieces of 1000 mg - about 1600-2000 rubles;
• 60 pieces of 1000 mg - costs around 3000 rubles.

When is Detralex prescribed?

Detralex is a symptomatic remedy for the relief and elimination of symptoms of chronic venous insufficiency. It is prescribed for chronic varicose veins in men and women and for symptoms of acute and chronic hemorrhoids.

Detralex is indicated for non-infectious problems of the lymph circulation system and edema of the lower extremities, not associated with pathology of the cardiovascular and urinary systems. In other words, it is useful:

1. If you complain of pain in the legs;
2. If your leg muscles cramp;
3. When there is a feeling of fullness, buzzing, “weights tied to the legs”;
4. For “tired legs”, even in the morning;
5. When the ankles and legs swell on both or one side;
6. The subcutaneous tissue of the legs is loose, painful, the skin over it is hyperemic or pigmented, dry, pronounced corns on the heels, there is hyperkeratosis;
7. For trophic ulcers of the legs;
8. For manifestations of hemorrhoids.

Drugs similar in pharmacological properties

Analogues of this group have a similar effect, but they contain other active ingredients.

Antistax

Venotonic contains natural extract of red grape leaves containing flavonoids. These substances protect veins from damage and increase the contractile activity of blood vessels. Antistax is used in the treatment and prevention of chronic venous insufficiency, varicose veins, chronic hemorrhoids, thrombophlebitis. Venotonic should not be taken by children, pregnant or lactating women.

Venozol

Used to eliminate venous stagnation. Venozol reduces the permeability of the venous walls, preventing plasma from leaking into the soft tissues. The active ingredient (horse chestnut seed extract) quickly relieves swelling and fatigue. Tablets should not be taken during pregnancy and breastfeeding, individual intolerance and kidney disease.

Troxevasin

Rutin derivatives have a beneficial effect on vascular walls and quickly eliminate swelling. Troxevasin has a pronounced tonic and antioxidant effect. The medicine is used in the treatment of early stages of varicose veins. It must be taken for at least six months. The drug is cheaper than Detralex, which helps save money.

Anavenol

Venotonic has protective and anti-edematous properties. Anavenol restores vascular patency and normalizes blood circulation. Prescribed for varicose veins, post-thrombotic disease, thrombophlebitis, trophic ulcers.

Composition and release form

The composition of the drug "Detralex" includes 500 mg of micronized flavonoid fraction (Purified micronized flavonoid fraction), in which diosmin is 90% (450 mg), hesperidin is 10% (50 mg).

Auxiliary components: gelatin, magnesium stearate, MCC, sodium carboxymethyl starch, talc, purified water. The composition of the drug "Detralex" can be found in the annotation.

Shell: macrogol 6000, sodium lauryl sulfate, premix for po/o orange-pink color (magnesium stearate, glycerol, hypromellose, iron dyes - yellow and red oxides, titanium dioxide).

The release form of Detralex is film-coated tablets. In blisters of 15 pcs., package No. 30; No. 60.

Statistically, the effect of the drug has been demonstrated for the following venous plethysmographic parameters: venous capacity, venous distensibility, venous emptying time.

The medicine is dose-dependent, and the effect of treatment is observed when used at a dosage of 1000 mg per day.

"Detralex" also increases the tone of the veins, which is achieved by reducing the rate of venous emptying, data obtained from occlusion plethysmography. In patients with signs of severe microcirculation disorders after a therapeutic course with this medication, an increase in capillary resistance is noted, which was assessed during angiostereometry.

In addition, the effectiveness of the drug in the treatment of chronic venous diseases, as well as in the treatment of hemorrhoids, has been proven.

Cheap analogues of Detralex are not difficult to find.

Course treatment with Detralex

In each case, the duration of use of the medication may vary. This depends on the severity of symptoms and possible complications, which are often observed with varicose veins and similar pathologies. The usual short course lasts 2 weeks, during which the patient takes 2 tablets per day.

If the disease progresses, the duration of use of the product is at least 6 weeks. Patients with chronic and advanced forms of varicose veins can be prescribed long courses of 3-5 months. The dosage of the drug should not exceed 1000 mg per day.

When prescribing a medication for long courses, a specialist usually examines the patient at least once every 2 weeks to evaluate the effect of the drug and note improvement.

Many patients say that the effect of using the tablets is not observed for 2-4 weeks. This is due to the gradual accumulation of active substances in the body. It is after 2-4 weeks that the first result appears.

Detralex 1000 instructions for use for varicose veins

Detralex has a wide range of applications. Indications for use of the drug can be divided into several main groups. This:

• Symptomatic treatment of chronic venous insufficiency;
• Preparation for surgical medical procedures for chronic venous insufficiency and recovery in the postoperative period.

Detralex can be used both as an independent remedy and as one of the elements of complex therapy. The advantages of the drug include the fact that it can be used for treatment at any age, including the elderly.

The study showed that Detralex shows high effectiveness in the treatment of varicose veins and moderate effectiveness in the treatment of lymphedema.

Detralex should not be prescribed if you are hypersensitive (allergic) to the active ingredients or excipients present in this medicine. It is not recommended for nursing women to take the tablets.

The tablet should be taken per os (“by mouth”, by swallowing) during meals.

For venous-lymphatic insufficiency, the recommended dose is 1 tablet x 2 times a day: the first tablet in the middle of the day, the second tablet in the evening.

When venous circulation is impaired, the greatest therapeutic effect is ensured by a combination of drug therapy with a balanced and healthy lifestyle: it is advisable to avoid prolonged stay in an upright position (on your feet), long exposure to the sun, and it is also recommended to reduce excess weight. Walking and wearing compression stockings (selected by a specialist) are recommended, which helps improve blood flow and blood distribution to organs.

The drug Detralex does not affect the ability to drive a car or perform work activities that require a high speed of physical and mental reactions.

Cases of overdose with this medicine have not been described. Possible symptoms of overdose: nausea, vomiting, stool disorders (diarrhea, constipation), dyspeptic symptoms.

In case of overdose, you should immediately seek medical help.

Therapeutic measures: it is necessary to artificially induce vomiting or immediately rinse the stomach with a probe (in the first 1–2 hours after taking the medicine); symptomatic therapy adequate to the patient’s condition is indicated.

Side effects:

Detralex or Troxerutin which is better

Troxerutin is a popular analogue of Detralex not only because of its inexpensive price, but also its high efficiency.
It is used for chronic venous insufficiency, during post-thrombic state, post-phlebitic syndrome and diabetic angiopathy. Troxerutin is often prescribed in the postoperative period for the removal of dilated veins, as well as their sclerosis. The product helps eliminate pain from serious injuries, including dislocations. In the form of an ointment, it is used in the treatment of hemorrhoids. When inserting tampons with the drug into the rectum, rectal inflammation is eliminated, as well as bleeding is stopped.

• remove inflammation in soft tissues and venous beds;
• relieve swelling;
• increase the elasticity of veins and tone blood vessels;
• improve the outflow of lymph and blood;
• strengthen vascular walls;
• cleanse the vessels of all excess.

When choosing between Detralex and Troxerutin, it is important to base it not only on the price, but also on the list of indications and contraindications. The French remedy can be used with virtually no restrictions, while the analogue has a number of restrictive conditions

Troxerutin has excellent anti-inflammatory properties, therefore it is very effective in acute varicose veins.

Side effects

Adverse reactions caused by treatment can manifest themselves in the gastrointestinal tract, central nervous system and dermis. If negative effects of treatment are detected, you should stop taking Detralex and consult a specialist.

Most often, taking Detralex provokes disturbances in the functioning of the gastrointestinal tract: diarrhea, vomiting, etc. In rare cases, the appearance of colitis or abdominal pain is observed.

Adverse reactions from the central nervous system are rare and can manifest themselves in the form of malaise, occasional headaches, and dizziness.

Hypersensitivity to the components of the drug can cause hives, irritation, and itching. In some cases, swelling of the eyelids, lips or face may occur.

Side effects

Adverse reactions during treatment with Detralex 1000 are mild in severity.

Nervous system

There were complaints of general malaise, headaches/dizziness;

Gastrointestinal tract

Patients often reported the development of diarrhea, nausea/vomiting and dyspepsia;

Less often they complained of pain in the abdominal area;

Skin covers

Rare cases of the development of angioedema have been described;

Occasionally, rashes accompanied by itching, urticaria, and isolated swelling in the area of ​​the lips/eyelids/face were recorded.

Additional instructions

The use of this drug when the patient's hemorrhoids worsen does not involve the cancellation of other courses of treatment in the anal area. If there is no therapeutic effect in eliminating symptoms, you should see a doctor to prescribe another treatment option.

If you have venous circulatory disorders, you should lead a healthy lifestyle, combined with courses of medical therapy. Experts recommend that the patient walk, normalize his body weight, and avoid prolonged exposure to the open sun. Staying on your feet for a long time brings a lot of harm. It would be a good idea to wear stockings with a special effect that will improve blood circulation.

Patients undergoing treatment with Detralex can drive.

special instructions

When using Detralex, discontinuation of other medications is not required. If there is no effect from the medicine, it is better to consult a doctor.

The active substances do not affect the functioning of the nervous system. Therefore, you can drive vehicles and work with machinery. Drinking alcohol during treatment is not recommended.

During pregnancy and lactation

Experiments were carried out on animals. The studies did not reveal any negative effects on the development and formation of the fetus. Therefore, the medication is approved for use by pregnant women. There is no data on the effect of the substance on breast milk; the drug is not recommended for nursing women.

The medication is approved for use by pregnant women.

Use in childhood

The instructions do not say that childhood is considered a contraindication. But Detralex is not used in the pediatric field.

Scheme of use of the drug Detralex in the treatment of acute hemorrhoids and during maintenance therapy

* Indications, contraindications, method of use and dose, features of use, adverse reactions, detailed information, etc., see the instructions for medical use of the drug Detralex 500 mg. Approved by Order of the Ministry of Health dated 11.01.2016 No. 6 R/s No. UA/4329/01/01 and instructions for medical use of the drug Detralex 1000 mg, approved by Order of the Ministry of Health dated 11.05.2018 No. 907 R/s No. UA/4329/01/02 .

Analogs

Detralex can be bought at any pharmacy. If for some reason the medicine cannot be purchased, you can select analogues:

1. Phlebodia 600.
2. Venarus.
3. Vasocket.

They have a similar composition and therapeutic effect. But such drugs are expensive. Therefore, there are cheaper analogues:

1. Troxevasin.
2. Troxerutin.
3. Angionorm in suspension.

There are analogues of the drug that are cheaper.
Before choosing an analogue, you need to read the annotation and consult a doctor.

Which Detralex is better 1000 or 500?

Detralex 500 has 2 times less active ingredients. This means that the effect is not as strong as the drug with a dose of 1000 mg. Which one is better to choose depends on the course of the disease. For an acute process, a medication with a dosage of 1000 mg is suitable. For chronic varicose veins and hemorrhoids, the choice should be Detralex 500.

For chronic varicose veins and hemorrhoids, the choice should be Detralex 500.

Stories from our readers

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There are a large number of analogues of Detralex, and in case of varicose veins, these drugs are used to strengthen blood vessels and restore blood flow. They differ in prices, components included and release forms. A phlebologist will help you choose a drug that causes the minimum number of side effects.

Detralex for varicose veins

Chronic venous insufficiency or varicose veins of the legs is a group of symptoms caused by impaired blood flow in the veins of the lower extremities and changes in the permeability of the vascular walls. This disease is more common in women. It occurs when the valves in the veins that prevent blood from flowing back do not close due to increased pressure. As a result, the veins stretch, which, in turn, leads to their increased permeability. Blood proteins and blood plasma begin to flow through the venous wall into the surrounding tissues. This leads to swelling of the tissues surrounding the veins. If small vessels are compressed, this, in turn, leads to ischemia and the formation of trophic ulcers.

The main factors causing venous insufficiency:

• Overweight;
• Sedentary lifestyle;
• Hereditary factors;
• Sedentary work or work with limited movement;
• Chronic constipation;
• Pregnancy, hormonal changes, use of hormonal drugs in women;
• Wearing tight underwear and clothing.

Chronic venous insufficiency is expressed by many symptoms, including:

• Feeling of fatigue, heaviness and bloating in the legs;
• Swelling of the extremities;
• Pain in the legs, especially after walking;
• Sensitivity disorders;
• Convulsions;
• Trophic changes in the skin and subcutaneous tissue
• Trophic ulcers.

There are several stages of varicose veins:

Stage I – morning fatigue of the legs, swelling in the evenings, disappearing in the morning;

Stage II – constant swelling, pigmentation disorders, thickening and redness of certain areas of the skin, itching, and the appearance of eczema;

Stage III – the appearance of trophic ulcers that are difficult to treat.

All stages of the disease are accompanied by pain of varying intensity, a feeling of crawling sensations, evening cramps, and numbness in certain areas of the skin.

In the early stages of the disease, compression bandages, tights, socks and stockings are used as therapeutic agents. It is also possible to treat the disease with physical therapy.

Detralex is able to relieve symptoms such as heaviness and pain in the legs, swelling, and night cramps. The drug also reduces the fragility of capillaries, affects the resorption of hard-to-heal trophic ulcers,

Venotonic creams and ointments can be used simultaneously with the use of Detralex for varicose veins.

Indications for taking Detralex

The French drug consists of 90% purified micronized flavonoid substance diosmin.
Additionally, it contains hesperedin. Both active components exhibit angioprotective and venotonic properties. Detralex is effective if necessary:

• increasing the tone of the venous walls;
• reducing the permeability of the capillary network;
• increasing lymph outflow;
• preventing the adhesion of leukocytes to the endothelium;
• minimizing the effect of mediators on venous valves;
• reducing the intensity and frequency of seizures in the lower extremities;
• reducing swelling in the legs;
• reducing pain;
• slowing down the progression of the formation of ulcerations on the skin due to trophic disorders;
• reducing leg fatigue;
• relieving the bursting sensation from the venous membranes.

Indications for taking Detralex are:

• a feeling of heaviness and fullness in the lower extremities;
• pain symptoms;
• increased fatigue of the lower extremities;
• phlebeurysm;
• haemorrhoids;
• venous insufficiency of various types.

Composition and release form

The main active substance of Detrolex is bioflavonoids, 90% of which are represented by the purified microionized fraction of diosmin, the remaining share is accounted for by other bioflavonoids in terms of hesperidin.

The production of Detralex was launched by the French company Servier. It comes in only one form - film-coated tablets. Russia acquired a license for the right to produce it, it is produced by Serdix LLC. There is a suspension packaged in sachets of 1000 mg, 900 mg of which is diosmin, 15 and 30 pieces each. The yellowish suspension has an orange flavor.

Original tablets with a film of delicate yellow-pink color, 500 mg each (diosmin 450 mg) are packaged in 30 and 60 pieces. In the manufacture of tablet forms, tablet-forming auxiliary components are used (gelatin, magnesium stearate, MCC, talc, sodium carboxymethyl starch). The coating is made from special premixes.

Detralex does not exist in the form of suppositories, ointments, gels or creams.

What composition?

The active components of the drug are considered harmless, as they are of plant origin. Details about these substances can be found in the following table:

It is worth noting that these substances are also available in the form of independent medications, but in combination they give excellent results in the treatment of varicose veins.

Additional elements included:

• cellulose;
• magnesium stearate;
• glycerol;
• hypromellose;
• iron oxide;
• sodium lauryl sulfate.

The medicine also contains a fraction of flavonoids, so it is considered a pharmaceutical drug with phlebotropic action.

The tablet dissolves very well in the stomach and breaks down into small particles, which allows the drug to enter the vascular wall much faster and have a therapeutic and restorative effect.

Detralex analogues and prices

Detralex analogues are divided into 3 groups:

1. Complete analogues (generics), similar in composition and mechanism of action;
2. Partial analogues, slightly different in composition, but with the same pharmacological effect;
3. The composition is different, but the formological group and mechanism of action are similar.

Complete analogues are widely known:

Partial analogues are similar in composition. They contain only diosmin at a dosage of 600 mg:

• Diosmin - domestic analogue, 610 rubles. for 30 tablets;
• - manufacturer France, costs 665 rubles. for 30 tablets, a cream with that name is produced in Latvia and sells for 428 rubles;
• Vasoket - German tablets 771 rub.;
• Phlebofa -, Russia, 30 tablets for 903 rubles;
• Venolen is a Russian drug for 419 rubles. for 30 tablets.

Similar in action:

• Capsules - containing extract from ginkgo biloba leaves, 30 pieces, 555 rubles, there is a gel with the same name. Ginkor Fort is contraindicated in hyperthyroidism; it should not be combined with MAO inhibitors;
• Antistax tablets with extract from red grape leaves, 560 rub. for 20 tablets;
• Troxevasin is the basis of troxerutin (there is a drug with the same name) or vitamin P, capsules are available in 50 pieces for 405 rubles, gel 40 g for 224 rubles.

The list of analogues does not end there; venotonics and angioprotectors are widely represented by pharmacological drugs and dietary supplements, topical agents (ointments, lotions, gels and creams), for example, based on the horse chestnut plant.

Prices for Detrolex are as follows:

1. Sachets 1000 mg, 30 per pack, 1,500 rubles;
2. Sachet 1000 mg, 15 per package, RUB 785;
3. Tablets 60 pieces 2530 rub.;
4. Tablets 30 pieces 1422 rub.

When changing a drug to a similar one, you must carefully read the instructions, because contraindications and side effects may differ significantly.

Where to buy Detralex

Detralex can be bought at almost any pharmacy. For those who find it more convenient to buy from an online pharmacy with delivery, we provide several options:

• IFC Pharmacy. Available in dosages of 500 mg and 1000 mg. Packages of 30 and 60 pills. Delivery in Moscow by courier and in Russia by mail.
• Online pharmacy WEB.RU. There are only packs of 30 pieces, but at a lower price. Many delivery options in Moscow, St. Petersburg and Russia.
• Europharma. The largest European selection at quite Russian prices. Moderate delivery prices in the capital and regions.

Course of treatment for varicose veins

The course of treatment with Detralex for varicose veins can be up to 1 year according to the indications of the attending physician, but not less than several months. The prescription of the drug is carried out by a doctor after examination and is individual. In this case, not only the course of treatment can vary, but also the dosage regimen of tablets within the permitted limits of the instructions for use.

Most often, the medication dosage regimen is as follows: 2 pieces per day, 1 at a time. You need to take tablets with meals: 1 at lunch, 2 at dinner.

Incomplete analogues of Detralex

Incomplete analogues most often contain one component of Detralex. The effectiveness of treatment with such drugs is almost the same. With timely administration of incomplete analogues of Detralex for varicose veins, the treatment effect will be good.

Phlebodia

An excellent medicine is Phlebodia, an analogue of Detralex. The medicine contains granulated diosmin. One tablet form contains 600 mg of the active ingredient.

Take the analogue for varicose veins of the legs, 1 tablet per day. It is better to drink the medicine during meals. For varicose veins of the small pelvis, the drug is taken 1 tablet per day.

If the patient has worsening hemorrhoids, then the drug is taken 2-3 tablets per day. After relief of the acute condition, treatment can be continued at 600 mg per day. Course therapy lasts 2-3 months.

Phlebodia can be used for the treatment of varicose veins during gestation from the second trimester of pregnancy. The analogue does not harm the fetus after the first trimester. The medicine must be taken in therapeutic doses. Treatment of venous insufficiency in pregnant patients must be carried out under the supervision of a gynecologist, therapist, or phlebologist.

Phlebodia is not indicated for children under 18 years of age, pregnant patients in the first trimester, during breastfeeding, or patients with allergies to Phlebodia components. The main undesirable manifestations include: headache, nausea, allergic reaction in the form of rash, urticaria. The price of the Phlebodia analogue is equal to the cost of Detralex. The daily dosage required for treatment is much less, which justifies its price.

Vasocket

An excellent drug is Vasoket, an analogue of Detralex in tablets. It is produced by German. Vasoket contains diosmin. One tablet form contains 600 mg of active substance. The cost of one package of the analogue (30 tablets) is 630 rubles.

It should be taken for varicose veins at 600 mg daily for 3-4 months. In the presence of trophic ulcers, treatment lasts six months. For patients with hemorrhoids, the medicine is prescribed at 1200-1800 mg per day. Hemorrhoid therapy lasts 6 months.

Phlebodia and Vasoket are good analogues of Detralex for hemorrhoids. They are much easier to take. The patient only needs 2-3 tablets per day. The effectiveness of these medicines is high. The drugs can be used even in pregnant women with hemorrhoids from the second trimester of pregnancy.

How to take it correctly

The use of Detralex for varicose veins can be very long-term. It is necessary to understand: in order to achieve maximum effect, it is necessary to select the correct dosage and additional measures for the treatment and prevention of the disease.

How to take and how to drink Detralex for varicose veins?

The original instructions for the drug say that there are 3 periods of pharmacokinetics after taking Detralex for varicose veins and other vascular diseases:

• Drug accumulation.
• Metabolism in the liver.
• Effect on blood vessels and blood.

The dosage of Detralex should be in correlation with the severity of the disease and its clinical manifestations.

The use of Detralex for varicose veins can be very long-term

Treatment course for varicose veins with Detralex

For varicose veins, tablets must be taken every 12 hours. The drug is taken with meals. If it is not possible to take it strictly after 12 hours, you can take Detralex one tablet in the morning and evening. You should only drink water in small quantities. For the treatment of varicose veins, the approximate course of treatment is 60 days. In severe cases, the duration of treatment can increase to 90 days.

How to take Detralex for the treatment of varicose veins and chronic venous insufficiency?

For the treatment of chronic venous insufficiency, which may be a manifestation or consequence of varicose veins, you should take 1 tablet 3 times a day or 2 tablets 2 times a day. A phlebologist will help determine the best treatment option.

With the development of thrombophlebitis or simply phlebitis, the drug is taken 3 tablets twice a day. You can also change the combination for convenience and take 2 tablets every 8 hours.

You should understand: treatment of thrombophlebitis and thrombosis with Detralex will not give the desired effect without the use of drugs from other groups, such as anticoagulants and NSAIDs.

Treatment of thrombophlebitis and thrombosis with Detralex
Sometimes the drug is prescribed before vein removal. In this case, the medicine for varicose veins Detralex is taken 1 tablet 3 times a day. The course of treatment is 1 week before surgery and 45 days after.

How long to take Detralex?

As already mentioned, for each pathology the course of treatment takes a different time. In order not to overdo it or, on the contrary, not to finish treatment ahead of time, you should consult a doctor who knows who needs to take what dose.

To whom the drug is not prescribed and possible adverse reactions

Detralex is not prescribed if the components of the main and auxiliary composition are intolerant

Particular attention should be paid to intolerance to fructose, which is included in the flavor and taste improver of the suspension in the sachet. It is not recommended to prescribe the drug to women who are breastfeeding due to the fact that the effect of the drug on an infant receiving breast milk has not been studied

For women bearing a child, Detralex is approved for use, since studies on laboratory animals have not revealed a teratogenic effect on the offspring. There is no negative effect on reproductive function.

The adverse reactions that occurred were mild. They can be divided into two groups:

1. Frequently occurring;
2. Rarely encountered.

The first includes:

• Malaise without specific complaints;
• Digestive disorder;
• Diarrhea;
• Nausea;
• Vomit.

Rarely:

• Inflammation of the colon;
• Abdominal pain;
• Headache;
• Dizziness;
• Rash and itching on the skin;
• Quincke's edema.

Typically, adverse reactions develop at an increased dose of Detralex, but there were no indications of an overdose of the drug. There were no cases of drug poisoning; there is no antidote.

There is also no data on the interaction of the drug with other drugs, but it is known that alcohol reduces the therapeutic effect of Detralex. This is not so much due to interaction as due to the worsening of the disease in response to a dose of alcohol.

Detralex: indications for use and contraindications

Detralex tablets in the instructions for use have the following indications for use:

1. Varicose veins of any stage of development as a therapy to eliminate the symptoms of venous-lymphatic insufficiency:

• feeling of heaviness in the lower extremities;
• painful sensations in the legs;
• feeling of tiredness in the legs;

1. Acute hemorrhoids, as a symptomatic treatment.

Contraindications for taking medications include:

• allergic reactions to the components of the drug.

The medicine is prescribed with caution during breastfeeding, since there are no studies on the risks for mother and child.

Side effects of the medicine

Side effects of Detralex are distinguished systemically:

1. Nervous system:

• dizziness;
• headache;
• general weakness;

1. Digestive system:

• diarrhea;
• nausea;
• vomiting;
• dyspeptic disorders;
• colitis;
• stomach ache;

1. Skin covering:

• rash;
• itching;
• hives;
• swelling of different localization;
• very rarely, angioedema may develop.

Any unwanted side effects of Detralex that occur in the patient must be reported to the attending physician to adjust treatment. There are no known cases of drug overdose. However, if you suspect it, you should immediately seek qualified medical help.

Detralex during pregnancy and breastfeeding

Animal studies have not revealed the development of teratogenic effects in pregnant women. Since the registration of the drug, possible side effects on the mother and fetus are unknown. The use of Detralex during pregnancy is permitted under the supervision of the attending physician according to indications.

The use of the drug Detralex during breastfeeding is not recommended. This is due to the lack of research data on lactating women. This is written in the instructions for the tablets.

Compatibility of Detralex and alcohol

Concomitant use of Detralex and alcoholic beverages is not recommended. This is due to the following mechanism:

• drinking alcohol causes an increase in blood pressure;
• this leads to vasodilation;
• then blood stagnation occurs due to increased blood flow;
• all this reduces the effectiveness of the drug, and sometimes worsens the course of the disease.

Brief description of Detralex

"Detralex" is a venotonic agioprotective drug developed by French specialists. The main active ingredients are diosmin (450 mg) and hesperidin (50 mg). The instructions for use state that the action of Detralex is aimed at restoring the walls of blood vessels, so doctors recommend it for:

• elimination of venous insufficiency of the lower extremities;
• reducing swelling;
• elimination of pain;
• relieving tension and fatigue in the legs;
• relief from hemorrhoidal exacerbation.

The drug reduces the distensibility of the veins and the stagnation of blood in them. Therapy with Detrolex is aimed at increasing the activity of blood flow and reducing the distensibility of the walls of blood vessels, as well as reducing their permeability and normalizing metabolic microprocesses in the vascular wall. The nodules formed in hemorrhoids are precisely dilated blood vessels in some places with stagnant blood. It follows from this that Detralex for hemorrhoids is a very effective remedy.

Detralex tablets consist of a micronized fraction; the active substance is quickly absorbed into the blood vessels and begins its effect almost instantly. The half-life in the body is 11 hours. The drug is excreted in feces (86%) and urine (14%).

Description

Detralex is a French drug used to treat venous insufficiency resulting from varicose veins.

Composition and properties

Each tablet contains:

• diosmin (450 mg);
• micronized flavonoids (500 mg);
• hesperidin (50 mg);
• magnesium stearate;
• pregelatinized starch;
• distilled water;
• iron oxide red;
• titanium dioxide;
• sodium lauryl sulfate.

The drug has the following actions:

• Increases elasticity and reduces the extensibility of venous walls. Diosmin eliminates pathological permeability of capillaries and eliminates blood stagnation.
• Strengthens the contractile activity of vascular walls. With long-term use of the drug, the time for venous emptying decreases. In case of severe disruption of blood flow, the drug helps to increase the stability of capillaries and restore blood supply to tissues.
• Relieves swelling caused by impaired outflow of blood and lymph. The drug can be used for varicose veins affecting the veins of the lower extremities, pelvis and esophagus.

Advantages and why analogues are needed

Detralex is highly effective; in most cases it is well tolerated by the body. The drug quickly eliminates pain, swelling and fatigue in the legs. However, there are reasons that make using the drug impossible:

• Presence of side effects. When taking tablets, digestive disorders, nausea, headaches, and inflammatory processes in the intestinal mucosa may occur. If these symptoms do not disappear over time, the dosage is reduced or the drug is replaced.
• Allergic reactions. In case of individual intolerance to the components of the drug, rashes occur in the form of erythema and urticaria, an allergic runny nose and severe itching appear. Against the background of a long-term course of an allergic disease, a dangerous complication may arise - Quincke's edema. The drug should be discontinued when the first signs of allergy appear.
• Presence of contraindications. Detralex is not prescribed to pregnant and lactating women, as well as to patients under 18 years of age.
• High cost of the drug. The tablets must be taken for at least 3 months, which involves large material costs. This is the main reason why patients try to replace Detralex for varicose veins with cheap analogues.

Troxevasin

Both drugs belong to the category of phlebotonics and, in comparison with others, perform their functions best. Their action is aimed at improving lymphatic drainage from painful areas, improving vascular tone, influencing pathological processes localized in blood vessels, and increasing the elasticity of venous walls. Both medications thin the blood and prevent the formation of blood clots and the development of venous insufficiency.

Which of these medications is best to use depends on the type and extent of the disease. If a patient develops varicose veins, then both drugs can be used simultaneously, which will stop the inflammatory process in the veins, eliminate various complications and stop destruction in the tissues.

“Detralex” or “Troxevasin” - it’s difficult to choose.

Experts indicate that the drug Detralex provides a very positive phleboprotective effect. At the same time, the effect of the drug “Troxevasin” is somewhat weaker. However, in cases where phlebitis, that is, inflammation of a vein, is diagnosed, preference is given to this particular medication, since it is the one that copes better with such pathology than Detralex. For hemorrhoids, there is also a high effectiveness of use, however, it should be remembered that “Troxevasin” for hemorrhoids is used, as a rule, in the acute period of the disease, and “Detralex” is used in the treatment of chronic forms and the prevention of such pathology.

Both “Troxevasin” and “Detralex” help quite effectively in eliminating the phenomena of blood stagnation in the venous bed. As a result, it is possible to eliminate such phenomena during the occurrence of acute forms of the inflammatory process, which experts consider a very important and irreplaceable advantage of medications of this pharmacological category.

So this is a good analogue of Detralex for hemorrhoids.

Complete structural analogues

Such drugs are called generics. They are produced by Russian, Indian, Ukrainian and Belarusian pharmaceutical companies. The main advantage of full analogues is their low price, making venotonics accessible to all categories of patients.

Venarus

The effective Russian analogue of Detralex contains the same active substances. It increases the tone of smooth muscles, reducing the distensibility of the venous walls. The drug quickly relieves swelling of the legs, eliminates signs of inflammation, and prevents the formation of blood clots. Venarus is used in the treatment of hemorrhoids. They can replace Detralex. After completing the full therapeutic course, hemorrhoids decrease in size. Side effects of venotonic include:

• general weakness;
• headache;
• allergic skin rashes.

Phlebaven

It is a high-quality replacement for Detralex. Used for varicose veins of any location. Allowed for use during pregnancy and breastfeeding. The medicine increases the elasticity of venous walls, normalizes blood circulation, eliminates signs of inflammation, and helps fight hemorrhoids. The drug allows you to quickly cope with the manifestations of chronic venous insufficiency.

Consumer Opinion

Analyzing numerous reviews, we can come to the conclusion that the principle “More expensive is better” does not always work. There are positive reviews about cheap affordable analogues. For example, Natalia, 27 years old. After giving birth in the maternity hospital, hemorrhoids appeared, “a lump came out.” I took Ginkor Fort for 5 days; upon discharge, no node was found.

Georgy writes that he is very pleased with the results of taking Detralex, the swelling has gone, the heaviness in his legs is gone, and he doesn’t have cramps at night. She notes slight pain in the stomach while taking the drug, but it has gone away. True, I had to change my lifestyle (quit smoking, walk more), but Georgy is happy about it.

Zhanna noted that the swelling went away while taking Detrolex, but the excruciating headaches made her doubt whether she should continue taking the expensive drug with side effects.

Before starting treatment, you should inform your doctor about the presence of concomitant diseases and the use of drugs from other pharmacological groups, including oral contraceptives.

How to find a cheap analogue of an expensive medicine

To find an inexpensive analogue of a medicine, a generic or a synonym, first of all we recommend paying attention to the composition, namely the same active ingredients and indications for use. The same active ingredients of the drug will indicate that the drug is a synonym for the drug, pharmaceutically equivalent or a pharmaceutical alternative

However, we should not forget about the inactive components of similar drugs, which may affect safety and effectiveness. Do not forget about the instructions of doctors; self-medication can harm your health, so always consult a doctor before using any medication.

Overdose and additional information

No negative effects on the body have been recorded following an overdose. If functional disorders occur while taking the medication, you should immediately consult a doctor.

When carrying out treatment with Detralex, you should know some points:

• alcohol and venotonics are incompatible;
• the prescription and determination of doses and duration of the course should be carried out by a doctor;
• Exceeding the treatment period is unacceptable - if symptoms persist, it is necessary, together with the doctor, to determine a different strategy for combating the disease;
• driving a car and complex machinery while taking the drug is acceptable, since the drug does not affect the speed of the body’s reactions;

Do not combine medication with alcohol consumption

• maintaining a gentle diet will make it possible to make the most effective use of the medicinal properties of the medication;
• this medicine is not intended for children;
• Daily walks will help restore blood circulation in the pelvic area and legs.

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Now answer the question: are you satisfied with this? Is it possible to put up with this? How much money have you already wasted on ineffective drugs? That's right - it's time to end them! Do you agree? That is why we bring to your attention the method of Marta Volkova, who spoke about an effective and inexpensive way to get rid of HEMORRHOIDS forever in just 5 days... Read the article >>>

Contraindications

Numerous studies confirm the safety of the drug Detralex. The contraindications for it are as follows:

• individual atypical immunity;
• lactation period in women.

During pregnancy, the medicine is used quite often, since no teratogenic effects have been identified when taking it. However, during breastfeeding it is better to avoid these tablets, since there is no information about the penetration of the active ingredients of the drug into breast milk.

List of similar drugs

Since it is quite problematic to find Detraven in Russia, it is necessary to establish whether drugs with a similar composition and similar therapeutic effects are available for sale in pharmacies in our country.

Since the combination of diosmin and hesperidin is an excellent and, perhaps, optimal remedy for combating venous pathologies, a lot of drugs based on these flavonoids are manufactured.

The main criterion for the difference between these products is only the degree of purification of the active and auxiliary components, as well as the price per package.

• Phlebodia 600, made in France. The phlebotonic agent is highly tolerable, has low rates of side effects, and is approved during pregnancy. The average price varies from 600 rubles for 15 tablets.
• Detralex French venotonic, the initial cost of the package is 660 rubles.
• Venozol is a drug based on diosmin and hesperidin, prescribed for varicose veins, CVI, trophic ulcers, thrombophlebitis, hemorrhoids. Children under twelve years of age, pregnant and lactating women are prohibited from taking this medicine.
• Antistax is an Australian-made drug whose main purpose is the treatment of venous diseases. One package will cost the patient 510 rubles.
• Troxevasin is a Bulgarian venotonic produced in the form of capsules, costing from 300 rubles.

Detralex reviews

Often, most people lead an incorrect lifestyle: they move little, eat completely unhealthy food, and much more. All this together gives results that do not have the best effect on the veins and overall health. Also, girls who wear high heels are more likely than others to be concerned about problems with veins. The drug Detralex can come to the rescue, which will cope perfectly with the problems of veins and Hemorrhoids too.

Active ingredient : Hesperidin

Is the drug registered? : check ☜

Medicine added: 2010-05-03. Instructions updated: 2016-12-21

Analogues and substitutes

☠ Attention!

Dummy medicines - how Russians are being scammed or what you shouldn’t spend money on!

Course of treatment for hemorrhoids

The standard duration of treatment for acute or chronic hemorrhoidal disease is seven days. After this, the drug must be stopped. If the symptoms of the disease continue to be present, then it is necessary to consult a proctologist and determine another direction in the fight against the disease. Sometimes, the doctor may extend the use of the tablets.

Depending on the indications and general condition of the patient, the daily dose of the drug and the duration of the course of therapy are determined by the doctor.

Pharmacodynamics and pharmacokinetics

Detralex tablets
Pharmacological action: Detralex maintains the tone and elasticity of the vascular wall, strengthens the walls of capillaries.

Against this background, the phenomena of stagnation in varicose veins are reduced. Detralex also has a positive effect on lymphatic vessels, by improving lymph outflow.

Pharmacokinetics: Detralex is completely eliminated from the body after 22 hours. The main part of the substance is excreted by the digestive organs, a smaller part is excreted by the kidneys. The rate of excretion decreases with impaired renal function or intestinal dysfunction.

When to use

Before taking Detralex, you need to undergo an in-person examination with your doctor. You should also take a general blood test, coagulogram and blood biochemistry.

The main reasons why you will be prescribed this venotonic may be:

• night cramps;
• swelling;
• trophic pathologies of the skin of the lower extremities;
• venous ulcers;
• heaviness in the legs and other pain;
• signs of hemorrhoids in all forms;
• surgery associated with risks of venous insufficiency.

In the latter case, tablets are prescribed both during preparation for surgery and during the recovery period.

Clinical trials have shown high results against hemorrhoids and venous diseases of the legs

Patient reviews

As for reviews from patients, there are many more of these and, also, they are all very different. The general consensus is that the drug is expensive. But despite this fact, people continue to use Detralex because of its effectiveness. Everyone agrees that health is still more valuable. And with the exception of a small number of patients who suffered from the side effects of Detralex, the majority of patients are very satisfied with the beneficial effect of the medication in reducing such unpleasant symptoms. There is an opinion that Detralex, produced in Russia, unfortunately, does not have such a positive effect. Therefore, according to patients, attention should be paid to the country of manufacture. Detralex, produced in France, is exactly the medicine that has a guarantee of eliminating symptoms, according to users. Basically, patients notice improvements that appear within a few hours after taking Detralex. Comparing it with other drugs, a huge part of patients prefer Detralex, and after trying it, they no longer switch to similar medications even at a lower price. There have been cases of acute hemorrhoids that appeared during pregnancy. Following the doctor's prescriptions, ointments, sea buckthorn oil, and suppositories were used, but nothing helped. Detrolex in such cases has proven maximum effectiveness. And only when taking it, the symptoms finally stopped bothering the patient after three weeks, taking a course of treatment with Detralex. Noticeable improvements appeared on the second day. After a week of taking it, the nodes became significantly smaller, as the external ones retracted. Many patients are satisfied with the results of the drug, but do not forget that it may not be suitable for everyone. Therefore, consultation with a doctor is necessary. Although there are cases where Detrolex was taken without a doctor’s prescription, as the doctor prescribed other medications. Fortunately, Detralex is a drug that can be dispensed at a pharmacy without a prescription. Many patients resorted to its use despite the fact that another treatment was prescribed for them. It should be remembered that each organism is unique. This does not mean that you need to experiment, but if the prescription and doctor’s advice do not help you in case of varicose veins or hemorrhoids, then it would not be a bad idea to try Detrolex. By strictly following the recommendations described in the instructions and adhering to an adequate dose (this information is described in the article), a solution to the problem can come very soon. Also maintain a healthy lifestyle in general. It is not recommended to drink alcohol or smoke while taking this type of medication. And this also has an undeniable negative impact on the symptoms of the disease. Pay attention to the country of manufacture when purchasing Detrolex. Since the original Detralex, produced in France, has proven its effectiveness more than once. The same cannot be said about Detralex, produced in Russia. The price for them is the same.

Dosage regimen for hemorrhoids

Detralex is often prescribed as part of complex therapy. This ensures maximum effectiveness of measures to treat complex forms of the disease.

One version of such a comprehensive approach looks like this:

• the drug "Detralex" - twice a day according to the schedule suggested in the instructions;
• treating affected areas with antibacterial creams (for example, Levosin);
• lubricating the skin adjacent to the affected area with petroleum jelly;
• use of rectal suppositories;
• maintaining medical diet No. 3.

It is very important not to forget that Detralex for hemorrhoids is taken after meals.

Features of therapy, compatibility with other drugs

You can buy Detralex at any pharmacy without a prescription. In accordance with the annotation, the best therapeutic effect from Detralex requires compliance with the following rules:

• Strictly control body weight. This will reduce additional pressure on the veins of the legs, relieve swelling and normalize blood circulation and lymph outflow;
• Don't give up physical activity. Detralex thins the blood, and additional stimulation of blood flow is mandatory for successful therapy;
• Regularly wear compression hosiery, the degree of compression of which is determined by the doctor, depending on the stage of varicose veins;

Since Detralex tablets are often prescribed by phlebologists as a complex therapy for varicose veins, it is important to consider its compatibility with other drugs. Detralex combines well with antibiotics prescribed for advanced stages of inflammatory venous processes

The opinion that Detralex is compatible with alcohol is erroneous, since alcoholic beverages reduce the therapeutic effect of the tablets. Treatment with Detralex for varicose veins involves complete abstinence from drinking alcohol.

Possible adverse reactions

During clinical studies, only mild adverse effects were reported:

• nausea, vomiting, unstable stool, abdominal pain;
• weakness, headache or dizziness;
• allergic reactions.

If such symptoms appear, you should stop taking the medication and consult a doctor. It is likely that this is caused by some other reason. If this is confirmed, treatment with Detralex can be continued.

The drug does not affect attention and the ability to control machinery, including transport. There have also been no cases of adverse interactions with other medications.

We recommend reading the article about the treatment of veins and blood vessels in the legs. From it you will learn about the causes and mechanism of development of varicose veins, symptoms of the disease, treatment methods and preventive measures.

Characteristics of the medicine

If a person is taking this drug, the instructions must be read before taking the medication. Capsules are the main form of this medication. This is a medicine that is effective in circulatory problems. It is known that venous blood flows from various organs. In the case of inflammatory diseases of the veins, circulation becomes difficult. Detralex at a dose of 500 mg increases vascular tone and has an angioprotective effect.

Angioprotectors are drugs that are widely used to treat cardiovascular pathology. These drugs dilate veins, increase the resistance of small vessels, improve metabolic processes, reduce swelling and signs of inflammation. Detralex is included in a comprehensive regimen of conservative treatment for hemorrhoids and is used in the postoperative period. The main active ingredient of the drug is diosmin. The medicine is produced in the form of film-coated capsules.

The action of the drug is aimed at eliminating the main mechanisms causing hemorrhoids. The drug Detralex effectively relieves the main manifestations of hemorrhoids and promotes rapid recovery.

Detralex

"Detralex" - tablets with venotonic and angioprotective action. The medicine is based on substances of plant origin - flavonoids.

The drug Detralex is a medicine for oral administration

When using a product with angioprotective properties, the following goals are achieved:

• Excessive elasticity of the veins decreases - swelling is removed, hemorrhoids disappear;
• the resistance of capillaries increases - their permeability decreases;
• the overall tone of the venous system improves.

There are only two active ingredients in the drug:

• diosmin – each tablet contains 450 mg;
• Hesperidin – 50 mg.

A unique technology patented by the French company Servier was used in the production of the medicine. Its essence lies in the so-called micronization of diosmin. Thanks to this, its absorption capabilities are significantly increased, which allows the medicine to be more fully absorbed by the body and begin to act faster.

In addition to the active ingredients, the small pink-orange tablets contain auxiliary ingredients:

• microcellulose;
• gelatin;
• talc;
• water;
• magnesium stearate;
• sodium carboxymethyl starch.

To treat diseases of acute and chronic hemorrhoids, the drug Detralex is used.
Each tablet is covered with a special coating, which ensures the dissolution of the pill at the required point in the gastrointestinal tract. The shell mainly contains hypromellose. “Detralex”, its composition is patented, is manufactured in the Russian Federation under license from the French pharmacological company Servier.

When taking the medicine, hemodynamics significantly improve and the adhesion of leukocytes to the endothelium decreases. All this leads to a reduction in damage by mediators to the valve leaflets of the veins. The time of venous emptying is also reduced.

Instructions for using Detralex 1000

The instructions describe the composition and pharmacological properties of the drug Detralex 1000, give the method of taking the drug and its dosage regimen, talk about side effects and contraindications.

Form, composition, packaging

Detralex is produced in the form of tablets with an oval-shaped, orange-pink film shell. The inside of the tablet is yellow with a heterogeneous structure. There are risks to sharing on both sides.

The active component is the flavonoid fraction in purified and micronized form in terms of diosmin 90% and hesperidin 10%. The supplement consists of gelatin, purified water, magnesium stearate, talc, microcrystalline cellulose, sodium carboxymethyl starch type A.

The coating consists of some sodium lauryl sulfate, yellow iron oxide, glycerol, titanium dioxide, red iron oxide, hypromellose, magnesium stearate, macrogol 6000 as a polishing agent.

They sell tablets in cardboard packaging, which contains three blisters with nine tablets and a dozen pills with three/six blisters.

Storage period and conditions

The drug Detralex 1000 does not require special storage conditions. The shelf life of the tablets is up to three years. The maximum room temperature is no more than thirty degrees.

Pharmacology

Properties of Detralex 1000:

• angioprotective;
• venotonic.

Its action is to reduce stagnation in the veins and their distensibility, as well as to reduce capillary permeability.

The therapeutic effect of the tablets is shown in the treatment of chronic venous diseases on the lower extremities and hemorrhoids.

Pharmacokinetics

The drug is metabolized quite actively. The half-life is approximately eleven hours. Excretion is carried out with urine and feces.

Indications

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The use of Detralex is indicated for:

• varicose veins – eliminates accompanying symptoms;
• the same ailment for the purpose of prevention;
• lymphostasis;
• all forms of hemorrhoids;
• thrombophlebitis and postthrombophlebitis syndrome;
• phlebectomy (before and after surgery).

pharmachologic effect

The effect of the drug is based on the ability of the main active ingredient - diosmin - to increase the tone of the veins. At the same time, the vessels become less elastic, the walls of the capillaries become stronger. Hemodynamics improve, stasis phenomena decrease. By stopping the production of prostaglandins, the drug has an anti-inflammatory effect. Detralex prevents the formation of free radicals, which are the main cause of damage to the walls of blood vessels. After taking the tablets, the outflow of lymph from the intercellular space is optimized. In the body, Detralex is transformed to phenolic acids and excreted by the liver; the half-life is 11 hours.

Tips for use

To get the maximum effect when treating varicose veins with Detraven, it is necessary to carry out complex therapy. Topical preparations are also used for this purpose. Usually, for varicose veins of the legs, the tablets are taken for 3 months, after which they take a break. If such therapy does not bring any results, an additional examination is prescribed, after which the drug is changed. To get rid of the lesion as quickly as possible, you need to completely reconsider your lifestyle.

Also follow these guidelines:

• Bring your body weight back to normal;
• Wear compression garments;
• Avoid spending long periods in the bathroom;
• Walk as much as possible;
• Follow all doctor's recommendations;
• Massage your limbs regularly;
• Take a contrast shower every evening;
• Avoid wearing uncomfortable and high shoes.

How to take Detralex for varicose veins

Varicose veins are a pathology that is more than relevant for modern people. A patient of any age and profession may need to take the drug itself or an analogue of Detralex for varicose veins. The disease leads to the fact that a person’s legs often begin to swell, blood stagnates in the vessels, and inflammation begins.

All this leads the patient to serious complications if treatment is not started on time. Each of us wants our legs to remain healthy and beautiful for as long as possible. Detralex is a unique drug that can relieve a patient of varicose veins once and for all. Let's learn more about all the nuances of using the product.

All Detralex reviews: reviews from doctors and patients

Doctors' reviews about Detralex In general, doctors' opinions on the treatment of varicose veins and hemorrhoids do not always coincide. Many doctors, given the high cost of the drug, do not dare prescribe it to their patients, using cheaper options. Although, sometimes, after much suffering, the patient continues to ask for prescriptions for other more effective drugs, since they often do not get satisfactory results from other drugs. Therefore, doctors very often end up resorting to the recommendations of Detralex as the only effective drug for the treatment of varicose veins and hemorrhoids. Moreover, in cases where there are chronic vein pathologies, doctors often prescribe Detralex for two courses per year. Doctors notice improvements in their patients' symptoms and see how the results are maintained over time. That is, during rest between courses of treatment there are usually no relapses or deterioration of the patient’s condition. Venous symptoms do not bother the patient even with a chronic course of the disease. Therefore, according to doctors, Detralex has a beneficial effect not only on acute and sudden diseases of the venous system, but also on chronic diseases that last for a long time.

Can I take the drug after eating food?

It is allowed to take Detralex after meals. The maximum time gap between consumption of food and the drug should not exceed one and a half hours. During this period, the main dishes continue to be broken down in the stomach, and hesperidin and diosmin will participate in their digestion.

If more time has passed after eating, then together with Detralex you need to eat a salad, cottage cheese dessert or other foods that do not increase acidity. The fastest foods to enter the stomach will be puree soup, jelly, milk porridge and other liquid foods.

List of cheap Russian analogues

There are drugs that have the same release form and the same active ingredients. Complete analogues of the original medicine in composition and indications are generics. In addition, products are produced that contain only one of the active ingredients.

List of Russian analogues and substitutes:

1. "Venarus".
2. "Diosmin."
3. "Venolek."
4. "Venozol".
5. "Phlebofa."

Domestic analogues of Detralex are cheaper compared to the imported drug. The cost of a package of Diosmin tablets with a dosage of the substance of the same name is 500 mg - from 450 rubles. The price of Venarus tablets 1000 mg (30 pcs.) is about 1000 rubles, 500 mg is 630 rubles.

Dietary supplement "Venozol" - capsules with a dosage of 0.5 and 0.36 mg. The cost of packaging is in the range of 500 rubles (60 pieces). This amount is enough for one course of treatment (1 month), if you take 1 piece. twice a day.