Omnic Okas tablets - indications and instructions for use, composition, side effects and price

Omnic Okas is a medicine in capsule form that is used in the treatment of dysuria in benign hyperplastic processes.

Prostate hyperplasia is one of the most common urological diseases in older men.

Prostatic hyperplasia is formed as a result of the proliferation of cells of the glandular epithelium or stromal tissue of the prostate gland.

First, one or more nodules appear, they begin to enlarge and put pressure on the urethra. Because of this, problems with urination appear.

In benign tumors, unlike malignant ones, metastases do not appear.

Analogs

When choosing an analogue of Omnic Okas, you can note drugs that have the same active substance, i.e. tamsulosin, or medications that have the same effect. The first group of medications includes:

1. Adenorm. It is a hard gelatin capsule containing tamsulosin. Additionally, the composition includes spherical sugar, cetyl alcohol, talc, povidone. Refers to alpha1-adrenergic receptor antagonists. The effect of the drug is due to a decrease in the tone of the prostatic part of the urethra.
2. Proflosin. Another option for extended-release capsules. The intestines completely dissolve them. In addition to the same active ingredient, it contains yellow oxide, ethyl acrylate copolymer, talc, titanium dioxide, indigo carmine. In addition to correcting urodynamics, the drug regulates the metabolism of the prostate gland.
3. Sonizin. The excipients of this drug are calcium stearate, copolymer of methacrylic acid and ethyl acrylate, MCC, talc. The medicine is presented in capsules with a soluble gelatin shell. It has the same indications and contraindications as Omnic.
4. Focusin. Also capsules in a gelatin shell with the main active ingredient in the form of tamsulosin. Additionally, the composition includes dibutyl sebacate, silicon dioxide, talc, microcrystalline cellulose. The drug is a representative of the group of alpha-blockers.

Among the drugs that have the same principle of action are Dalfaz, Setegis, Avodart. These medications are often used in the complex treatment of prostate adenoma. They are prescribed together with alpha-blockers to enhance effectiveness. The operating principle of these analogues is the same. The drugs affect the smooth muscles of the prostate gland, thereby improving urodynamics.

Analogues of tablets "Omnic"

If necessary, the medication can be replaced with one of its synonyms or analogues. The most popular are: “Vesomni”, “Urorek”, “Avodart”, “Setegis”, “Alfater”, “Kornam”, “Alfirum”, “Dalfusin”, “Alfuzosin”, “Dalfaz”, “Sonirid Duo”, “ Terazosin", "Sonizin".

The cost of drugs similar to Omnik varies over a fairly wide range and depends on many factors (manufacturer, number of capsules or tablets in the package, active substance, its mass fraction in the drug). For example, a package of “Uroreka” containing 30 tablets will cost approximately 750 rubles, while a package of “Dalfaza” with the same number of pills will cost 2.2 thousand rubles.

Interaction with other medications

The combination of tamsulosin with enalaprim, nifedipine, atenolol does not lead to any interactions between the substances.

Parallel use of Omnic and cimetidine can cause an increase in the concentration of tamsulosin in the blood plasma, while combination with furosemide leads to a decrease in its concentration. In this case, adjustment of the dosage regimen when combining these medications is not required, since the concentration of tamsulosin in the blood remains within normal limits.

Glibenclamide, simvastatin, diclofenac, chlormadinone, amitriptyline, trichlormethiazide, diazepam, propranolol, warfarin do not affect the free fraction of tamsulosin in the blood. In turn, tamsulosin does not interfere with the free fractions of trichlormethiazide, diazepam, propranolol, and chlormadinone.

In addition, there were no interactions of tamsulosin with finasteride, salbutamol, glibenclamide, or amitriptyline.

When used simultaneously with diclofenac and warfarin, there is a possibility of increasing the rate of excretion of the active component.

Concomitant therapy with other alpha-1 receptor antagonists can lead to a decrease in blood pressure. It is better to find out in advance how to take Omnic tablets.

Pharmacological properties of the drug Omnic ocas

Pharmacodynamics. Tamsulosin selectively and competitively blocks postsynaptic α1-adrenergic receptors, especially α1A and α1D subtypes located in the smooth muscles of the prostate gland, bladder neck, prostatic urethra and detrusor. This causes a decrease in the tone of the smooth muscles of the prostate gland, bladder neck and prostatic urethra and an improvement in urine outflow. At the same time, the severity of symptoms of obstruction (emptying) and irritation (filling) of the bladder associated with benign prostatic hyperplasia decreases. The described effect of the drug on symptoms of obstruction and irritation persists with prolonged use. The ability of α1A-adrenergic receptor blockers to reduce blood pressure is associated with a decrease in peripheral vascular resistance. Omnic Okas in a daily dose of 0.4 mg does not cause a clinically significant decrease in systemic blood pressure both in patients with hypertension (arterial hypertension) and with normal initial blood pressure. Pharmacokinetics. Absorption. Omnic Okas is a prolonged-release tablet with a controlled release of the active substance based on a matrix using a non-ionic gel. This dosage form provides a prolonged and slow release of tamsulosin, which ensures exposure of the active substance with minor fluctuations over 24 hours. After oral administration, 57% of tamsulosin is absorbed in the intestine. The rate and extent of absorption do not depend on food intake. Tamsulosin has linear pharmacokinetics. After a single dose of Omnic Okas on an empty stomach, the maximum concentration of the active substance in the blood plasma is achieved after 6 hours. In the equilibrium state, which is achieved on the 4th day of taking the drug, the maximum concentration is observed after 4-6 hours, regardless of food intake. The maximum plasma concentration increases from 6 ng/ml after the first dose to 11 ng/ml at steady state. As a result of prolonged release, the minimum plasma concentration of tamsulosin is 40% of the maximum concentration, regardless of food intake. Distribution . Plasma protein binding - 99%. The volume of distribution is insignificant - up to 0.2 l/kg body weight. Metabolism. Tamsulosin hydrochloride is not subject to the first pass effect through the liver and is slowly metabolized in the liver to form pharmacologically active metabolites that retain high selectivity for α1A-adrenergic receptors. Most of the active substance is found in the blood unchanged. Excretion. Tamsulosin hydrochloride is excreted in the urine, 4–6% unchanged. The half-life of tamsulosin with a single dose and at steady state is 19 and 15 hours, respectively.

Side effects

The use of Omnic can cause some undesirable effects from different systems of the human body. CVS can manifest itself through dizziness, increased heart rate, and sometimes orthostatic hypotension may occur.

Possible reactions of the nervous system are headaches, impotence, chronic fatigue syndrome. From the gastrointestinal tract, diarrhea, constipation, nausea, and vomiting may occur. Not often, but it happens that the reproductive system reacts with the development of retrograde ejaculation (rejection of sperm into the bladder).

We looked at the phenomena that Omnik is capable of causing (cheaper analogues exist, but they also contribute to the development of similar reactions). "Omnic Okas", in addition to everything described above, can cause fainting (this happens quite rarely), priapism (prolonged and painful erection not associated with sexual arousal). Sometimes patients develop rhinitis. Allergic reactions caused by both medications are similar: urticaria, skin rash, itching, angioedema (rare).

Reviews from men with prostatitis

There are many reviews on the Internet about the drug “Omnik” for prostatitis, and most of them are positive. Certain negative responses from men are associated with the presence of undesirable effects, after which they were forced to stop using the capsules.

The very first week of using Omnik normalizes body temperature, pain in the lower abdomen decreases, and the urge to go to the toilet becomes less frequent. The therapeutic course lasts a month, then it is repeated again. Some patients take the course every year in late autumn. They say that it is impossible to hope for a complete cure for male diseases, but the effectiveness of the drug has been proven.

A number of patients have improvements, but there is a significant side effect, which is mentioned in the instructions. Because of the drug, the blood vessels dilate greatly, if a man has chronic rhinitis and other pathologies, the nose stops breathing, it is difficult to get rid of such a deficiency. You have to use strong drops that constrict blood vessels. In this case, urination is still almost normal, only excess residual urine remains. Thanks to this effect, even patients suffering from a runny nose still recommend Omnic.

There are rarely reviews in which men talk about strong side effects - disappearance of ejaculation, dizziness, drop in potency by 70%, awakening at night due to poor condition. Although urodynamics improve, the degree of this effect is insignificant, so patients prefer more powerful drugs with fewer side effects.

We looked at how the course of treatment with Omnik for prostatitis works.

Omnik Okas and Omnik

On sale you can find the drug “Omnik okas”, 30 tablets per package. They are 100% synonymous, that is, they contain the same active ingredient (tamsulosin) in an identical concentration (400 mcg). It is not surprising that patients suffering from prostate adenoma often wonder what the difference is between these medications. Medicines differ in their dosage form: “Omnic” is available in capsule form, and “Omnic Okas” is available in tablet form.

Moreover, the tablets of the latter are characterized by the controlled release of tamsulosin. That is, they are characterized by a constant concentration of the active component, observed throughout the day in the body. A similar amount of the drug allows the active substance to have an equally strong effect on the muscle tissue of the prostate throughout the whole day. In addition, the absence of changes in tamsulosin concentration leads to a reduction in the likelihood of developing side symptoms. However, the instructions for Omnic Okas tablets must be strictly followed.

Omnic - indications for use

The drug Omnic is a drug intended for the treatment of urinary disorders due to diseases such as prostatic hyperplasia, prostate adenoma, stones in the ureter and kidneys, and so on, as stated in the official instructions for use. Reviews about the drug are mostly positive.

The drug is used on an ongoing basis - a course of treatment with the drug is unacceptable, since it will have absolutely no effect.

Most often, doctors prescribe Omnic as an auxiliary and symptomatic therapy designed to alleviate the course of the underlying disease, which cannot be treated or cannot be cured for a certain period of time.

The cheapest analogues of Omnik

Analogues that are as close as possible to Omnik Russian analogues are:

• Tamsulosin;
• Tamsulosin-Teva
• Proflosin;
• Hypersimple.

All of them are produced in the country, some under license. Tamsulosin - both versions of the drug differ only in the manufacturing company: Evalar and Obolenskoe FP.

The release form is a capsule with a shell that controls the rate of dissolution of the active substance, containing Tamsulosin 0.4 mg. Capsule coating made of ethyl acrylate copolymer, talc, methacrylic acid. During the manufacturing process, the components are dissolved in water, which evaporates and is not present in the finished product.

Prescribed for symptoms of benign hyperplasia and urinary problems. Take 1 capsule per day. During treatment with the drug, it is not recommended to engage in work that requires quick reaction and concentration of tension. This is, first of all, driving vehicles and working in hazardous industries.

During treatment, it is not recommended to engage in work that requires quick reaction and concentration of tension.

Contraindications for taking Tamsulosin are the same as for other drugs, Omnic analogues:

• renal failure during exacerbation;
• severe liver failure;
• orthostatic hypertension - a drop in pressure in an upright position of the body;
• hypersensitivity and intolerance to tamsulosin and its compounds.

When taking the drug, doctors recorded side effects of the drug. The frequency of their manifestations is from 0.1% of patients to 0.01%:

• pupillary constriction syndrome;
• retrograde ejaculation – release of sperm into the bladder;
• decreased libido;
• priapism – prolonged erection;
• angioedema;
• hives;
• itching;
• rash;
• vomit;
• constipation;
• rhinitis – nasal congestion, runny nose;
• sleep disturbance;
• tachycardia;
• headache.

All these effects appear in case of an overdose of the drug, when the patient independently takes an increased dose or is simultaneously treated with drugs that enhance the effect of tamsulosin.

How to use Omnik for prostatitis

It is very important to prescribe Omnic in the correct dosage. According to the instructions for use, you need to drink 1 capsule per day at a dosage of 400 mg, with a sufficient amount of liquid. In this case, it is forbidden to open and chew the capsule; it must be swallowed whole. If the doctor deems it necessary, the dosage may be increased.

It is usually recommended to take Omnic in the morning with breakfast, then during the day the patient will not be bothered by problems with urination. But if a man suffers from frequent urge to go to the toilet at night, a decision may be made to prescribe the drug in the evening, before bed. You cannot increase the dosage on your own; you need to consult a specialist.

The duration of treatment with Omnik is at least 2 weeks, and is determined individually by the attending physician. As a rule, the drug is prescribed for at least 2 months to achieve lasting improvement. Less commonly, therapy can last 3-6 months or even lifelong.

Many experts consider split use of the drug in several courses. This helps to obtain significant results and save the patient money. But such a course of therapy must be drawn up and supervised by a doctor. If you cancel Omnic ahead of time on your own, all treatment will be in vain and things will get worse.

Omnic is most often well tolerated by patients, but side effects may occur:

• tachycardia, decreased blood pressure and weakness;
• fast fatiguability;
• rhinitis;
• headache;
• nausea and vomiting;
• skin rashes.

Omnic often provokes a disorder such as retrograde ejaculation. According to the manufacturers, the Omnic Ocas form of the drug does not cause such complications. In any case, if signs of reverse ejaculation appear, you should inform your doctor. The specialist will probably decide to replace the drug with a more suitable analogue.

Contraindications and side effects

Obviously, Omnic Okas cannot be prescribed to patients with intolerance to tamsulosin or other substances in the tablets, as well as to patients under 18 years of age (due to the lack of clinical trials).

In addition, the tablets can critically lower blood pressure in patients with orthostatic hypotension and aggravate the condition of patients with severe liver failure

Additionally, tamsulosin should be prescribed cautiously to men with renal failure and hypotension. It is not recommended to combine alcohol and Omnic Ocas, so as not to disrupt the dynamics of its release

Among the side effects of tamsulosin, it is necessary to note deviations in the functioning of the nervous system. Patients often complain of dizziness, headaches and even fainting. Also, according to patient reviews, the drug can cause disturbances in the gastrointestinal tract - nausea, diarrhea and vomiting, and provoke allergic skin manifestations. In rare cases (less than 1% of respondents), the medicine caused disturbances in the functioning of the reproductive system, provoking, for example, retrograde ejaculation.

Omnic: side effects, contraindications and course of treatment

At the first symptoms of urinary problems, especially in older people, you should immediately consult a doctor for examination. You should not self-medicate, as this may be useless and even harmful.

Despite the fact that this drug is quite safe for health, it still has side effects. And in some cases, treatment must be carried out under the supervision of a doctor.

The side effects of taking the drug Omnik are as follows:

• dyspeptic disorders;
• headache;
• retrograde ejaculation;
• allergic phenomena on the skin: rash, itching, etc.;
• backache;
• sleep disturbance;
• decrease in pressure.

Contraindications for taking Omnic:

• tamsulosin intolerance;
• severe liver dysfunction;
• orthostatic hypotension.

Omnic treatment course

The duration of treatment with the drug depends on the disease (chronic prostatitis, prostate adenoma) and is determined by the doctor individually. These diseases are treated with both medication and surgery. Omnic as a medicine is simply irreplaceable for people for whom surgery is contraindicated.

The dose of the active substance is constant, starting from the first day of administration. The therapeutic effect of Omnic is not immediately felt. Relief occurs only after a few days, and a stable result occurs after two weeks. If the medicine is taken in the course prescribed by the doctor, the disease will not progress or become more complicated, and surgical intervention will not be necessary.

On the forums you can find positive reviews from both doctors and patients. The product is praised for its high efficiency and good tolerance by the body. But most importantly, it helps people avoid surgery.

Important! The article is informational and not advisory in nature. Only a doctor can prescribe treatment with Omnik!

Analogs

The drug from the Dutch pharmaceutical company is not the only one on the domestic market. Analogs of Omnic are presented in several types of drugs, both Russian and foreign:

• Tamzelin;
• Focusin;
• Hypersimple;
• Omsulosin;
• Tulosin;
• Sonizin;
• Proflosin.

Any analogue of Omnic contains 0.4 mg of tamsulosin. The only difference is in the additional components. Some contain more starch and talc, but less gelatin and dioxides. Others, on the contrary, include a large number of components of the capsule shell rather than excipients inside it. This circumstance does not affect the treatment of prostate diseases in any way.

They are taken once a day. Treatment regimens with analogues are identical to therapy with the original drug. The set of side effects is the same as that of Omnic. Even the cost of these drugs is not too lower than the original, and for many it is close to the price of Dutch tamsulosin.

Side effects of the drug Omnic ocas

Common side effects (1% but ≤10%) are dizziness (1.3%). Uncommon side effects (0.1%, but ≤1%) are headache, tachycardia, postural hypotension, rhinitis, constipation, diarrhea, nausea, vomiting, rash, urticaria, itching, retrograde ejaculation, asthenia. Rare side effects (0.01%, but ≤0.1%) are fainting, angioedema. Very rare (≤0.01%) - priapism. Cases of intraoperative instability of the iris (narrow pupil syndrome) during cataract surgery in patients taking tamsulosin for a long time have been described.

Pharmacokinetics

After oral administration, tamsulosin is quickly and almost completely absorbed from the gastrointestinal tract. Bioavailability of the drug is about 100%. Absorption slows down somewhat after eating. The same level of absorption can be achieved if the patient takes the drug after a normal breakfast each time.

The pharmacokinetics of tamsulosin is linear. After a single oral dose of 400 mcg, the Cmax of the active substance in plasma is achieved after 6 hours.

After repeated oral administration of the drug in a daily dose of 400 mcg, Css is achieved by the 5th day, while its value is 2/3 higher than the Cmax value after a single dose of the drug.

Plasma protein binding - 99%. Vd is insignificant and amounts to 0.2 l/kg.

Tamsulosin is slowly biotransformed in the liver to form less active metabolites. Most of the active substance is present in the blood unchanged.

Experimental studies have revealed the ability of tamsulosin to slightly induce the activity of microsomal liver enzymes.

Tamsulosin and its metabolites are excreted mainly in the urine, 9% of the dose is excreted unchanged.

T1/2 with a single dose of 400 mcg of tamsulosin after meals - 10 hours, after repeated doses - 13 hours.

Admission rules

The decision on the dosage of the drug Omnik, how long to take it, drawing up a treatment regimen for prostatitis and adenoma are the tasks of the attending physician. The following dosage of the drug is often suggested: 1 capsule or 400 mg per day.

For adenoma, Omnic should be taken at the same time in the morning or evening for greater effectiveness of the drug and its uniform distribution in the body. People over 18 years of age, as well as older people, can drink Omnik.

Omnic should be taken orally for prostatitis, washed down with a small amount of clean water at room temperature without gas. In this case, it is strictly forbidden to bite, chew the capsule or damage it in any other way, since the released active substance will be destroyed by gastric juice before it is absorbed in the intestine.

Only a specialist can say how long you can take Omnic without interruption. The duration of the course is 1-2 months, depending on the severity of the disease and the patient’s health condition. It is better to take the drug after the first breakfast.

The therapeutic effect is observed within 14 days after the start of treatment. The drug Omnic can be taken for preventive purposes under the supervision of a doctor 2 times a year. In this case, the duration of the appointment is calculated by the doctor.

For prostate adenoma, Omnic is most often taken; the course of treatment for prostatitis is determined by a urologist. The daily dose of the medicine is 1 capsule.

The possibility of using the medicine with other drugs depends on the type of medicine. After taking enalapril, atenolol, and theophylline, no negative interactions were identified. However, when taken simultaneously with cimetidine, a slight increase in tamsulosin plasma was found; in combination with diuretics, such as Furosemide, the concentration of the active substance tamsulosin decreases. This does not require dose adjustment.

It is important to know! During treatment, blood pressure may decrease, which can lead to fainting.

After taking the medicine, when dizziness and weakness appear, you need to sit down or lie down. These symptoms will go away in a few minutes. If necessary, you need to take medications that increase blood pressure.

Analogues and cost

Substitutes for the drug are:

• According to the active substance - Sonizin, Tamsulosin, Omsulosin, Taniz-K, Proflosin, Hyperprost, Tamzelin, Fokusin, Revokarin.
• According to the mechanism of action - Urorek, Alfuzosin, Alfuprost MR, Dalfaz retard.

Before using substitutes, you should consult your doctor.

The price of Omnic in 2019 is about 400 rubles per pack of 10 capsules.

Omnic is stored at temperatures from 15˚C to 25˚C. The shelf life of the drug is no more than 4 years.

The medicine should be kept away from children.

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There are contraindications. Specialist consultation required

2019, Eganov Egan Pavlovich. All rights reserved.

Features of taking tablets for prostatitis

To achieve the desired result from the treatment course, you need to correctly adjust the dosage of the drug taken. Only a urologist can do this. Taking into account the specifics of the disease and the individual characteristics of the body, the presence of other pathologies, the doctor will prescribe the necessary treatment.

Tablets are usually taken after breakfast, in the morning, washed down with still drinking water. Swallow the capsules completely, without chewing or opening. A single dosage per day is one tablet. This amount may vary, depending on the characteristics of the disease in each specific case.

How much to take “Omnik” for prostatitis? Omnic acts slowly, the therapeutic effect of the drug manifests itself when there is sufficient accumulation of the active substance in the body. A noticeable improvement in well-being occurs after two weeks of daily use of the medicine.

The duration of taking capsules is determined individually for each patient and ranges from 2 weeks to 3 months. On average, the course of therapy lasts 2 months.

Another popular drug for prostatitis is Omnic Okas. Let's consider it further.

Other foreign analogues

Imported analogues contain the same active ingredient as Omnic. Their prices vary slightly. Cheaper medicines contain either a lower dosage of the active substance or there are simply fewer tablets in the package.

• Omnik Okas. Manufacturer: Netherlands. Unlike Omnic, an overdose cannot occur and the number of side effects is much less.

Omnic Okas is not a capsule, but a small tablet that is easier to swallow. If Omnic is not suitable, then replacing it with Omnic Okas is the best option. The price of a large package is 1600 rubles. It is a little more expensive than Omnic.Terazosin. It is manufactured in three foreign countries at once: Israel, Canada, Macedonia. Helps eliminate the symptoms of prostate adenoma and contribute to the treatment of arterial hypertension.

A package of tablets costs about 1000 rubles. In Russia, some factories produce this drug at a lower price. So, under the Terazosin-Teva brand, the medicine costs 200 rubles. In this case, replacing with a cheap analogue does not affect the quality. Dalfaz. Joint work between Ukraine and France. Restores normal urination. The tablets are available only by prescription, have contraindications, a number of side effects and are not compatible with some medications.

Before use, it is recommended to carefully study the instructions. Price 1900 rubles per package. Only modern technologies are used in production.

Sonirid Duo. Manufactured in Hungary and Romania. Restores the functioning of the bladder and is used in the treatment of the prostate. The drug is constantly on sale, its price does not exceed 1000 rubles.

Setegis. Manufacturer: Hungary. Used for prostate adenoma and for combination with other drugs for arterial hypertension. The maximum dosage costs 1250 rubles.

Medicines for prostate adenoma are not intended for use by women. Their use during pregnancy is not only prohibited, but also very dangerous for the proper formation of the fetus. The list goes on and on, there are many medications, and which one to choose and what to replace the usual drug with should be decided together with your doctor.

Source life-sup.ru

Price for Omnic Okas

You can buy Omnic Okas in Moscow or any other city only with a doctor’s prescription. The price of the medicine is determined by the number of tablets in the package. It cannot be classified as cheap. The approximate cost is shown in the table:

Pharmacokinetics, pharmacodynamics

Tamsuzolin, according to its drug group, is a specific blocker of postsynaptic alpha1-adrenergic receptors, which are present in the smooth muscle structures of the prostate gland, in the prostatic urethra in men, and in the neck of the bladder. As a result of tamsulosin blocking these receptors, the muscle tone of the prostate, bladder, and prostatic urethra decreases. As a result, urination improves. Along with this, there is a weakening of the symptoms of bladder fullness and emptying in prostate adenoma, which is due to detrusor hyperactivity, as well as increased muscle tone of these organs.

Tamsulosin acts on alpha-adrenergic receptors type 1A 20 times stronger than on alpha-adrenergic receptors type 1B, which are located in the smooth muscle structures of blood vessels. Such a high selectivity of the substance makes it possible to avoid a clinically significant decrease in systemic blood pressure not only in patients with normal blood pressure values, but also in patients who suffer from arterial hypertension. That is, Omnik can be used to treat hypertensive patients.

Tamsulosin is well absorbed in the intestine, and its bioavailability reaches 100%. The adsorption process slows down somewhat if you combine taking the drug with eating food. The degree of absorption will be equivalent if the patient begins to take the drug continuously after tomorrow.

A special feature of tamsulosin is that it has linear kinetics. A single oral use of 0.4 mg of the substance leads to a maximum concentration in the blood after 6 hours, and constant daily oral use of 0.4 mg of the substance already on the 5th day leads to an equilibrium concentration. Tamsulosin is 99% bound to plasma proteins.

The active substance is metabolized in the liver tissue very slowly, resulting in the release of less active metabolites. Most of the substance taken is concentrated in the blood, and in unchanged form.

Clinical studies show that tamsulosin is able to slightly induce the activity of microsomal liver enzymes. For mild to moderate pathological changes in this organ, no dose adjustment of Omnic is required.

The unchanged active substance of the drug, as well as its metabolites, are eliminated through the kidneys, and the half-life of a single dose of 0.4 mg is 10 hours. If the application is carried out repeatedly, then this period is up to 13 hours.

In case of moderate pathological changes in the kidneys, adjustment of the dosage regimen is also not required, however, in severe forms of renal failure, caution is indicated when using the drug. So, what are Omnic tablets for?

So, what are Omnic tablets for?

Duration of treatment

Most patients begin to feel a clear lasting effect from taking Omnic 12-15 days after the start of treatment.
But this does not mean that the effect of the drug is not felt earlier. Many men who take this medicine claim that urinary problems caused by prostate adenoma are mostly eliminated after 5-7 days of daily use of the drug, and some felt relief within a few hours after drinking the first capsule.

If signs of an overdose of Omnic or persistent side effects of the drug appear, treatment should be suspended and consult with your doctor.

The course of treatment with Omnik is individual in each individual case and is determined by the doctor. This drug is taken for a long time, and the period of its use can range from several months to several years. Elderly patients diagnosed with prostate adenoma can take it lifelong to relieve symptoms.

Despite the well-known expression that “the main thing is not to grow old in your heart,” health after 50 years is not at all as strong as at 20.

And the point here is primarily not in lifestyle, but in natural processes associated with hormonal changes in the body.

One of the most common unpleasant diseases that occurs in mature men due to changes in the secretion of “male” hormones is prostate adenoma. But fortunately, this disease can be successfully combated with the help of modern medications - prostate α1D-adrenergic receptor blockers.

And one of the most famous and effective drugs in this group is Omnic (the active ingredient is tamsulosin). But in order for this remedy to produce the best effect, you need to adhere to the doctor’s recommendations on how to take Omnic, and not interrupt the course of treatment before the time indicated by the doctor.

In the manufacturer’s instructions for the drug Omnik, in the “indications” column, a term is written that is incomprehensible to people far from medicine - “benign prostatic hyperplasia.”

Normal prostate and benign prostatic hyperplasia

Under this complex medical definition lies a well-known and unpleasant, but not fatal, age-related male disease - prostate adenoma. It is a benign formation that occurs due to the growth of tissue around the urethra.

The most obvious and typical signs of prostate adenoma are:

• frequent urination;
• difficulty and/or inability to completely empty the bladder;
• difficult and painful urination;
• sometimes – the presence of blood in the urine.

Tamsulosin, the active substance of the drug, acts on the receptors of the muscles of the prostate gland and bladder, reducing the tone of the muscles of the prostate and bladder neck. As a result, the outflow of urine improves, and discomfort during urination is eliminated.

Prostatitis fears this remedy like fire!

You just need to apply it.

The course of treatment with Omnik is individual in each individual case and is determined by the doctor. This drug is taken for a long time, and the period of its use can range from several months to several years. Elderly patients diagnosed with prostate adenoma can take it lifelong to relieve symptoms.

The main problem with prostate adenoma is that the disease negatively affects the process of urination, this can lead to a number of serious disorders in the body (vesicoureteral reflux, bladder stones, etc.). Therefore, you need to pay attention to the first manifestations of hyperplasia and go to the doctor to receive timely treatment.

The clinical classification of prostatic hyperplasia identifies several stages of disease development and, accordingly, treatment options. At the 1st stage, the detrusor hypertrophies compensatoryly, which ensures complete evacuation of urine. There have not yet been any disturbances in the functioning of the kidneys or upper urinary tract, however, signs of dysuria are already appearing in the form of changes in the frequency and duration of urination.

How many times does an adult man need to go to the toilet? Experts believe that the total average volume of urine excreted per day is about 1.5-2 liters, and the normal bladder capacity is 0.25-0.3 liters. Therefore, a healthy person should give about 4-5 milkings per day. Otherwise, dysuric disorders are observed, for the correction of which Omnic tablets are prescribed.

At the 2nd stage of development of prostate adenoma, the detrusor undergoes dystrophic changes, which gives insufficient contractility and, as a consequence, the appearance of residual urine - from 0.1 to 1.0 liters. This stage is accompanied by a change in the transport of urine in the kidneys and ureters, which leads to compensated renal failure. Dysuria persists, and there is a more frequent urge to go to the toilet, accompanied by pain.

It is better to start taking drugs for the treatment of adenoma without bringing the disease to the 3rd stage, at which the detrusor acquires decompensatory functions, the upper urinary tract is dilated, the renal pelvis and calyces are enlarged, and renal failure increases. Urine is retained chronically, involuntarily released at night and then during the day (paradoxical ischuria, based on urine overcoming the portion of the vesical sphincter).

The recommended daily dose is 400 mg or 1 capsule. It is advisable to take the drug at the same time of day so that the concentration of the substance in the blood is maintained at a constant level.

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Oral administration does not depend on food, but it is best to drink Omnic immediately after breakfast. Since most often the morning daily diet differs little, therefore the absorption and bioavailability of the drug will be at the same level.

The duration of the course is individual for each patient. But most often it is recommended to take capsules for 1-2 months 2 times a year for prevention. Or when symptoms appear.

The tablets should be taken with half a glass of boiled water at room temperature. In this case, you cannot chew or divide the capsule, since the site of absorption of the substance, the duration of dissolution in the intestine and the portion entry into the bloodstream change.

The effectiveness of the drug does not change when taking alcoholic beverages.

To get the effect of taking tablets or capsules, you should choose the dosage correctly.

To do this, it is recommended to visit a doctor who will assess the symptoms of the disease and prescribe a course of treatment suitable for the patient.

Usually Omnic is taken one capsule once a day in the morning, after meals. Take the capsule or tablet with water. You cannot open it, much less chew it, when taking it.

What effect can be expected and after what time?

The active component of the drug is almost 100% absorbed from the gastrointestinal tract immediately after administration.

• By improving the flow of urine, it alleviates the patient’s condition and blocks the development of corresponding complications in his body.
• A pronounced and lasting effect from taking tablets and capsules can be expected two weeks after the start of treatment.
• During this time, it must accumulate in the body. If the drug is used for 5 days in a row at the indicated dosage, its plasma concentration will triple compared to the first dose.

If the disease is not in an advanced stage, the therapeutic effect appears after a single dose of the medicine (after about 6 hours).

Omnic is not able to cure the disease completely. It only eliminates the problems associated with prostatitis, blocking the inflammatory process occurring in the body. Therefore, this drug should only be taken in combination with other drugs.

The main problem with prostate adenoma is that the disease negatively affects the process of urination, this can lead to a number of serious disorders in the body (vesicoureteral reflux, bladder stones, etc.). Therefore, you need to pay attention to the first manifestations of hyperplasia and go to the doctor to receive timely treatment.

At the 2nd stage of development of prostate adenoma, the detrusor undergoes dystrophic changes, which gives insufficient contractility and, as a consequence, the appearance of residual urine - from 0.1 to 1.0 liters. This stage is accompanied by a change in the transport of urine in the kidneys and ureters, which leads to compensated renal failure. Dysuria persists, and there is a more frequent urge to go to the toilet, accompanied by pain.

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To get the effect of taking tablets or capsules, you should choose the dosage correctly.

To do this, it is recommended to visit a doctor. who will assess the symptoms of the disease and prescribe a course of treatment suitable for the patient.

The active component of the drug is almost 100% absorbed from the gastrointestinal tract immediately after administration.

Most patients begin to feel a clear lasting effect from taking Omnic 12-15 days after the start of treatment. But this does not mean that the effect of the drug is not felt earlier.

The course of treatment with Omnik is individual in each individual case and is determined by the doctor. This drug is taken for a long time, and the period of its use can range from several months to several years. Elderly patients diagnosed with prostate adenoma can take it lifelong to relieve symptoms.

Interaction with other drugs

The combination with Enalapril, Nifedipine, Atenolol does not lead to any significant interactions.

Parallel use with Cimetidine causes a slight increase in the concentration of tamsulosin in the blood, and with Furosemide - a decrease in this indicator. Such combinations of drugs do not require adjustment of Omnic doses, since the concentration of the active substance in the blood plasma remains within the therapeutic norm.

“Simvastatin”, “Glibenclamide”, “Diclofenac”, “Amitriptyline”, “Chlormadinone”, “Trichlormethiazide”, “Propranolol”, “Diazepam”, “Warfarin” do not affect the free fractions of the active substance “Omnica” in the blood plasma. Tamsulosin, in turn, is not able to disrupt the free fractions of Diazepam, Trichlormethiazide, Propranolol, and Chlormadinone.

Interactions of tamsulosin with Finasteride, Glibenclamide, Salbutamol, Amitriptyline at the level of hepatic metabolism have not been identified.

Simultaneous use with Diclofenac and Warfarin helps to increase the rate of excretion of the active substance Omnica.

Parallel use with other alpha-1 adrenergic receptor blockers can lead to a decrease in blood pressure.

Let's look at the compatibility of Omnic and alcohol.

If you drink alcohol at the same time during therapy, unpleasant symptoms may occur. These include fainting, hypertensive crisis, tachycardia. The body becomes dehydrated, and with an excessive dose, death can even occur.

So there is absolutely no compatibility between Omnic and alcohol.

Mechanism of action

Omnik treatment courses allow you to achieve excellent results. Thanks to them, problems associated with impaired urine outflow disappear in patients diagnosed with prostatitis. The active substance of the drug blocks the receptors, and thereby relaxes the smooth muscles in certain parts of the genitourinary system.

The drug effectively eliminates irritation of the canal walls and relieves spasms in this area. The patient will feel significant relief within a couple of weeks after starting therapy.

The active substance of the drug is absorbed from the gastrointestinal tract in full after administration. It starts working immediately. The drug prevents the inflammatory process from spreading to healthy tissue and causing complications. With each new capsule taken, the therapeutic effect accumulates.

We suggest you read: How to massage the prostate with a tennis ball and how effective it is

If the patient takes Omnic for 5 days in the dosage prescribed by the doctor, then after this time the concentration of its active substance in the blood will become three times higher than after the first dose of the gelatin capsule.

By prescribing Omnik, the doctor offers the patient an individual course of treatment that helps alleviate the painful condition of prostatitis. It will be difficult for a specialist to take into account all the features of the body. Therefore, during therapy, a man may experience unexpected reactions to the drug itself. This phenomenon usually occurs after taking the first capsule.

Composition and release form

The medicine for prostate adenoma Omnic Okas is available in tablet form. Each tablet is coated with a yellow or brownish film, with the manufacturer’s inscription “0.4” embossed on one side. These numbers, as intended by the pharmaceutical manufacturer, reflect the concentration of the active substance in each tablet. The role of such a component is the well-known alpha1-adrenergic blocker tamsulosin, which is supplemented in Omnic Okas with secondary components - magnesium stearate and two types of macrogol.

In addition, the film coating of the tablets contains several dyes and stabilizers, but these ingredients are not biologically active. As for packaging, each cardboard box can contain one or three blisters of tablets - a total of 10 or 30 pieces. You can buy the drug at a pharmacy only with a doctor's prescription.

Omnik Okas and Omnik: what is the difference

To answer the question of how Omnik differs from Omnik Okas, first of all, you need to look at the differences in their chemical composition. Thus, a simpler analogue based on tamsulosin is supplied with such minor substances as talc, gelatin, MCC, methacrylic acid, sodium, calcium and others.

A similar chemical structure determines the difference in the pharmacokinetics of the drug. Omnic Okas, unlike its cheaper competitor, is a drug not with a modified, but with a controlled release of an alpha1-blocker.

Compound

The main component of the drug is tamsulosin hydrochloride. It is a white powder with a crystalline structure. The substance is poorly soluble in water, slightly soluble in glacial acetic acid and ethyl alcohol, and not at all soluble in ethers. The medicine is produced in the form of blisters with tablets, as shown in the photo. One piece contains 400 mcg tamsulosin. Additionally, the composition contains:

• Magnesium stearate – 1.2 mg;
• macrogol 8000 – 40 mcg;
• macrogol 700000 – 200 mg;
• purified water;
• shell – yellow opadry 03 F 22733 in the amount of 7.25 mg.

Instructions for use Omnic Okas

The medication belongs to the group of alpha1-blockers. Its action is to block receptors responsible for relaxing the smooth muscles of the urinary organs. As a result of taking it, its tone decreases, which helps speed up the rate of urination. This reduces the symptoms of hyperplasia, which eliminates the need for surgical intervention.

The tablets are characterized by a controlled release of the active substance throughout the day. They are not compatible with alcohol. After just two weeks of use, the following positive effects are observed:

• urination is normalized;
• the lumen of the bladder neck increases;
• decreased resistance to urine flow;
• normalization of blood supply to the bladder and metabolism in its muscles;
• pressure in the urethra decreases.

Indications

The main and only indication for the use of Omnic Okasa is prostate adenoma, which causes urination problems. The drug is necessary to relieve symptoms of the disease such as:

• feeling of incomplete emptying of the bladder;
• dripping after urination;
• frequent urge to urinate, including at night;
• weakened stream of urine;
• difficulty starting to urinate;
• urgency to empty the bladder.

Dosage

You can take the medicine regardless of food, but it is better at the same time. There is no need to chew the tablet so as not to disrupt the standard order of drug release. The optimal dosage is 400 mcg per day. This is one tablet. Omnic capsules are also accepted. Dosage does not require adjustment in case of liver or kidney failure. The course of treatment is not limited or determined by the doctor.

Side effects

The drug has a number of side effects. The first of these is an allergic reaction to the components of the medication. It causes skin rash, asthenic condition, itching and even urticaria. In more severe cases, angioedema and small pupil syndrome are noted. Other side effects include:

• vomit;
• nausea;
• priapism;
• dizziness;
• rhinitis;
• ejaculation disorder;
• fainting;
• diarrhea;
• orthostatic hypotension;
• feeling of heartbeat;
• constipation.

There are no cases of acute overdose of the drug, but theoretically they are possible. As a result, acute hypotension may develop, which requires additional administration of cardiotropic therapy and ensuring normal renal function. But the patient is not prescribed dialysis, because tamsulosin combines with proteins in the plasma. An overdose may be manifested by tachycardia and decreased blood pressure.

In such a situation, it is important to prevent further absorption of the drug. To do this you need to induce vomiting

More gentle methods include gastric lavage, activated charcoal, or an osmotic laxative. All these measures, including symptomatic ones, prevent the drug from continuing to be absorbed and making you feel worse.

Contraindications

This medicine may not be used to treat prostate hyperplasia in all cases.

It should be used with caution in chronic renal failure, arterial hypotension and severe impairment of renal function. The medicine is completely contraindicated for:

• severe liver failure;
• orthostatic hypotension;
• hypersensitivity to the components of the drug.

Effect of Omnic on the body

A course of treatment with Omnik for prostatitis is prescribed to normalize the outflow of urine. The drug contains a substance called tamsulosin, which is an alpha-blocker. Such substances affect certain receptors in the human body, which leads to relaxation of smooth muscles. Thus, Omnik helps eliminate the following symptoms for prostatitis:

• weak stream of urine;
• secretion of urine drop by drop;
• frequent urge to urinate;
• incomplete emptying of the bladder.

Many patients wonder whether Omnik treatment for prostatitis is effective. It is important to note here that the effect of therapy does not occur immediately; as a rule, patients notice visible improvements 5-14 days after starting to take the drug. In more rare cases, improvement occurs in the first days of use.

This effect is due to the ability of the drug to accumulate in the patient’s body. So, in the first 6 hours after taking the capsule, a tamsulosin concentration of 400 mg will be observed, but if the patient continues to drink Omnic daily, then after a week the concentration of the drug will almost triple. With long-term use, complete release of the drug is observed no less than 30 hours after taking the last capsule.

For prostatitis treatment to be effective, all medications must be prescribed by a doctor. Omnic tablets for prostatitis are always prescribed in complex therapy, along with antibiotics, anti-inflammatory drugs, vitamins and other necessary drugs.

If you take Omnic as the only medicine for prostate adenoma or chronic prostatitis, then you may not see a positive effect. Because the drug has only a symptomatic effect, it will improve the flow of urine. But Omnic will not relieve the patient of the infection, if any, which will most likely lead to a worsening of the condition.

In complex treatment, the drug has the following advantages:

• very convenient regimen, only 1 tablet per day;
• the risk of developing acute urinary retention is reduced;
• the risk of surgery for adenoma is reduced;
• has a pronounced effect even with large prostate adenoma;
• does not cause impotence;
• does not provoke hypertension, is safe for the elderly;
• does not provoke PSA levels, so the analysis for tumor markers due to taking Omnic will not be false;
• practically does not affect potency.

The disadvantage of Omnik treatment is the need for lifelong use of the drug, which is not economically viable for most elderly patients. The cost of the drug is about 1000 rubles for 30 capsules.

special instructions

Before you start using the drug, read the special instructions:

Use with caution in patients prone to arterial hypotension and with severe liver dysfunction. Before starting tamsulosin therapy, the patient should be assessed for the presence of other diseases that may cause the same symptoms as benign prostatic hyperplasia. Before starting treatment and regularly during treatment, a digital rectal examination and, if required, prostate specific antigen testing should be performed.

In patients with impaired renal function, no change in dosage regimen is required.

During the treatment period, it is necessary to refrain from engaging in potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Interactions of the drug Omnic ocas

No interactions were observed with the simultaneous use of tamsulosin hydrochloride with atenolol, enalapril, nifedipine and theophylline. When the drug was used in combination with cimetidine, a slight increase in the concentration of tamsulosin in the blood plasma was observed, and with furosemide - a decrease in concentration, but this does not require a change in the dose of Omnica Ocas. Diazepam, propranolol, trichlormethiazide, chlormadinone, amitriptyline, diclofenac, glibenclamide, simvastatin and warfarin do not change the free fraction of tamsulosin in human plasma. Tamsulosin also does not change the free fractions of diazepam, propranolol, trichlormethiazide and chlormadinone. In vitro, there was no effect of tamsulosin on the level of metabolism of amitriptyline, salbutamol, glibenclamide and finasteride by microsomal liver enzymes. Diclofenac and warfarin may increase the rate of elimination of tamsulosin. Concomitant treatment with other α1-adrenergic receptor antagonists can lead to a pronounced increase in the hypotensive effect.

Omnic and Avodart

These drugs are analogues of each other in their pharmacological group, but they contain various active substances that affect the pathological processes that are inherent in adenoma. The drug "Omnic" is a more symptomatic drug, which is intended to eliminate dysuric disorders (can normalize the process of urination) by relaxing the smooth muscle structures in the prostate. The drug Avodart, on the contrary, is designed to reduce the size of the tumor itself by reducing the concentration of dihydrotestosterone, which causes its growth. Both drugs are often used in combination therapy, where their effects complement each other.

The most popular synonyms for “Omnica” are: “Tamzelin”, “Urofrin”, “Taniz-K”, “Fokusin”, “Bazetam”, “Tamsulon-FS”, “Sonizin”, “Omniprost”, “Tamsulosin”, “Revokarin” ", "Alfatam", "Omsulozin", "Proflosin", "Omnic Okas", "Adenorm".

Reviews

In approximately 70% of cases, reviews of Omnic tablets are positive. Urologists often recommend the use of the drug for prostate adenoma, prostatitis, and other pathological changes accompanied by urination problems, when the relaxing effect of tamsulosin on the smooth muscle structures of the prostate actually eliminates the negative manifestations of the pathology.

To be fair, it should be noted that there are negative reviews about Omnic Okas tablets associated with the occurrence of side symptoms due to their use. The most significant of these are the development of retrograde ejaculation and hypotension. In addition, we should not forget that the prescription of the drug in the treatment of prostate adenoma is symptomatic in nature and is aimed at eliminating dysuric disorders, and full-fledged therapy for this pathology requires the use of medications of various groups and an integrated approach.

Among the negative characteristics of the drug, its relatively high cost is also noted. Patients and doctors note that it has a number of analogues and synonyms, the cost of which is significantly lower, and the effectiveness is at the same level.

We looked at what Omnic tablets are prescribed for.

Information about drugs

As a rule, the active ingredient in such medications is tamsulosin. There are many medications containing it, but their effect is to improve the flow of urine and reduce the symptoms of the disease.

One such drug is Omnic. This medicine is made in the Netherlands, the price ranges from 750 rubles. Omnic is produced in smooth capsules, which must be taken after meals with water. The medicine is prohibited for children and is sold only with a doctor's prescription. The drug can be taken by older people and those who have kidney problems.

Usually you can find an analogue for each medicine. However, you need to look not only at the price, but also at the manufacturer, reviews, and composition of the product. This drug has many analogues: Russian, Ukrainian, Belarusian and other foreign. The price ranges from 180-1500 rubles.

Method of storage and use, dosage of the drug

The medicine should be stored in a dry place, out of reach of children, at a temperature of no more than 25 °C; the shelf life should not exceed three years from the date of release of the drug. After the expiration date, the drug cannot be used - it must be completely discarded.

The drug is used strictly as prescribed by the attending physician - he can select the appropriate dosage for you, depending not only on the disease that needs to be stopped, but also on the general condition of the body, as well as the results of the examinations performed.

Standard Dosages and Applications

Typically, the drug is prescribed once a day, regardless of when you ate, if we are talking about capsules, or immediately after breakfast, if you take tablets.

It is not necessary to take the tablets in the morning; it is important to simply take them at the same time of day, since the active ingredient in the tablets gradually affects the body over 24 hours, while the capsules act almost instantly.

The tablet or capsule must be taken completely and cannot be divided or chewed. In addition, the drug does not have a specific period of use; as a rule, Omnic and Omnic Okas are prescribed for use on an ongoing basis or for a certain long period of time.

Pharmacokinetics of the drug

Each tablet of the drug contains tamsulosin hydrochloride, the release of which occurs slowly and over a long period of time. Such a controlled process is possible thanks to non-ionic helium, which is also part of the drug. This important component allows the release of the active component to be extended over 24 hours, which ensures maximum therapeutic effect with minimal doses of the drug.

After the active substance is released, it is absorbed by the walls of the intestines and stomach.

Omnic Okas has a cumulative effect. After passing through the bloodstream, the active substance enters the liver, where it breaks down into weakly active components that are contained in the blood plasma for a long time.

Omnic: what is it?

Many articles have been written about the drug Omnic. But to understand what Omnic is, you need to know about the mechanism of action of its main substance - tamsulosin hydrochloride.

Tamsulosin hydrochloride is an antagonist of alpha-1 adrenergic receptors, which are found in the bladder and prostate gland. The active substance Omnica blocks these receptors, ensuring relaxation of the smooth muscles of the bladder and prostate. Thus, the drug facilitates urination and provides a diuretic effect. The diuretic effect of Omnic is complemented by a reduction in irritation and inflammation due to benign prostatic hyperplasia. This is how Omnic has a comprehensive effect on the disease and treats it.

The drug Omnic is available in modified-release capsules. How does it work in treatment? After taking the medication, the capsule begins to act gradually. After the level of the active component has reached its maximum in the blood, it stops being released from the capsule. Over time, the active substance slowly enters the blood to maintain its required level. Thanks to this feature, the drug Omnik acts for many days, and its effect is long-lasting.

Proflosin, domestic and foreign

The drug is available in capsules with a shell similar to Tamsulosin. Even foreign medicine is more expensive than Omnik, within 100 rubles; domestic Proflosin has a price that is 15 - 20 rubles higher.

Excipients that provide prolonged dissolution:

• talc;
• microscopic cellulose;
• triethyl citrate.

The yellow, translucent shell consists of gelatin with the addition of iron oxide as a dye, titanium dioxide and indigo carmine.

Packages of 30 pcs for a monthly course and 90 pcs when prescribing long-term use of the drug.

Contraindications for use are similar to Omnic and Tamsulosin.

Diarrhea is a side effect of treatment with some drugs in this group

Side effects, in addition to those already identified for similar drugs, are very rare, less than 0.01%:

• fainting;
• dizziness;
• nervous excitement;
• diarrhea.

Proflosin affects reaction speed and the ability to concentrate. It is not recommended for drivers and workers in other professions that are associated with nervous tension and require a quick reaction, monitoring of many indicators at the same time and their analysis. For example, managing complex conveyors, power plant processes, rolling mills and work processes in hazardous areas.

Not compatible with alcohol and psychotropic drugs. It is quickly eliminated from the body, without showing a therapeutic effect, and can lead to a nervous breakdown.

How many times a day should you drink Omnic?

When treating hyperplasia, Omnic tablets are often combined with drugs that correct the condition of the body that led to adenoma. These may be hormonal disorders at the level of the gland itself or in the area of ​​the pituitary-hypothalamus ligament. The ratio of sex hormones (estrogens-androgens, prolactin, luteinizing and follicle-stimulating hormones) is also of great importance for the proper functioning of the prostate gland.

Hyperplasia may be caused by a violation of the synergistic effect of androgens with estrogens, which distorts enzyme reactions and a corresponding effect on some DNA chains that trigger the growth of prostate cells.

The main indication for prescribing the drug "Omnic" is various dysuric disorders associated with benign hyperplasia. The main active ingredient of the tablet is tamsulosin. This substance has the ability to reduce the increased tone of smooth muscles in the prostatic urethra, in the neck of the bladder, in the prostate itself, which provides a good outflow of urine and reduces irritation of the urinary canals.

Combination with alpha1A-adrenergic receptor antagonist drugs may enhance the severity of the hypotensive effect.

Average price of Omnic Okas: tablets No. 10 – 600 rubles; tablets No. 30 – 1600 rubles.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Omnik okas tab. counter. vysv. p/o 0.4 mg No. 10ZiO-Zdorovye CJSC/ORTAT JSC
• Omnik okas tab. counter. vysv. p/o 0.4 mg No. 30ZiO-Zdorovye ZAO

Pharmacy Dialogue* discount 100 rub. using promo code medside (for orders over 1000 rubles)

• Omnic Okas (tablet p/o 0.4 mg No. 10)

Europharm* 4% discount using promo code medside11

• Omnic ocas 400 mcg 10 tablets Societe/Bitner Pharma
• Omnic okas 400 mcg 30 tabIMMUNOLEX FZ

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Pharmacy24

• Omnic Okas 0.4 N30 tablets Astellas Pharma Europe B.V., Netherlands

PaniPharmacy

• Omnic Ocas tablets Omnic Ocas tablets p/o with control high.0.4 mg No. 30 Netherlands, Astellas Pharma Europe

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BIOSPHERE

• Omnic Okas 0.4 mg No. 30 tablet p.o. slow-release Astellas Pharma Europe B.V. (Netherlands)

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The action of Omnic in adenoma

The medicine Omnik works as follows. A substance called tamsulosin acts as an alpha receptor blocker. They are found in the muscles of the prostate and the tissues that make up the bladder. When blocking the receptors, a significant decrease in the tone of muscle fibers begins. This helps to significantly improve the functionality of the bladder and normalize the outflow of its contents.

Due to the effects of tamsulosin, the symptoms of the disease are quickly eliminated, even if other symptomatic remedies have not brought any effect.

An alpha blocker taken orally is gradually distributed and absorption occurs in the intestine. Its highest concentration in the human body is observed after about five hours. To treat prostate adenoma and eliminate the symptoms of the disease, patients are prescribed tamsulosin, which is the active substance of the drug Omnic.

Omnik is prescribed if there are problems with the functionality of the bladder, emptying is incomplete, and urine pressure is weak. If you have incontinence, you may need to use urinary pads. Adding Omnic to the therapy can help in this case as well.

Omnic and its analogues are not used in the treatment of the prostate if orthostatic hypertension is diagnosed. The same applies to cases where the patient has previously suffered from such a disease.

The drug should not be used in treatment when the patient has increased sensitivity to tamsulosin; an individual reaction to additional components has been noted. The drug is excreted mainly through urine, therefore, in cases of severe renal failure, its use is undesirable and can be hazardous to health. If liver failure is diagnosed, the possibility of using the drug should be discussed with a doctor.

Interaction

Co-administered Amitriptyline, Warfarin, Diazepam, Simvastatin, Propranolol, Glibenclamide, Trichlormethiazide, Diclofenac and Chlormadinone do not change the free plasma fraction of tamsulosin (in vitro), nor does tamsulosin affect the free fractions of Chlormadinone, Trichlormethiazide, Propranolol and Diazepam.

When taking other drugs from the group of alpha1-adrenergic receptor blockers in parallel, the hypotensive effect may be enhanced.

Combined use with Cimetidine can lead to a slight increase in the plasma content of tamsulosin, and with Furosemide - to its decrease. These changes do not require adjustment of the dosage of the drug Omnic Okas, since the plasma concentration of its active ingredient remains within acceptable limits.

In in vitro studies of metabolic transformations occurring in the liver, there was no interaction of tamsulosin with Finasteride, Glibenclamide, Salbutamol and Amitriptyline.

Concomitant use of Warfarin and Diclofenac may increase the excretion rate of tamsulosin.

When tamsulosin was used in combination with Theophylline, Atenolol, Nifedipine or Enalapril, no interactions were identified.

Side effects

During the course of treatment with Omnik, various side effects may occur, which are expressed as follows:

• In disorders of the cardiac and vascular system, which are very rare, and they are expressed mainly in dizziness, orthostatic hypotension, increased heart rate, and tachycardia.
• Disorders of the central nervous system (CNS) have been identified in only a few isolated cases, and these side effects are expressed in severe headaches and general loss of strength.
• In disorders of the genitourinary system after taking the drug, which very rarely occur in patients, and they are expressed in a malfunction of the mechanism for secreting seminal fluid.
• Disorders associated with the digestive system are very rare, and they are expressed in nausea, vomiting, diarrhea, and constipation.
• In very isolated cases, after administration, an allergic reaction occurs in the form of a skin rash, itching, and swelling.

Pharmacological properties

Pharmacodynamics

Tamsulosin is a specific competitive blocker of postsynaptic α1-adrenergic receptors, especially the α1A and α1D subtypes, which are responsible for relaxation of the prostatic urethra, bladder neck and smooth muscle of the prostate gland.

At a dose of 0.4 mg, the drug increases the maximum rate of urination, reduces the tone of the smooth muscles of the urethra and prostate gland, thereby improving the outflow of urine, and reduces the severity of symptoms of emptying and filling, in the development of which detrusor overactivity plays a significant role.

With long-term use of Omnica Ocas, the effect on the symptoms of filling and emptying the bladder is maintained, and the risk of developing acute urinary retention and the need for surgical intervention is reduced.

By reducing peripheral resistance, the drug can lower blood pressure. However, when used at the recommended daily dose, no significant change in blood pressure was observed.

Pharmacokinetics

Omnic Okas is available in the form of controlled-release tablets, made on the basis of a matrix using a non-ionic gel, which ensures a slow and prolonged release of the active substance, and sufficient exposure with slight fluctuations in the concentration of tamsulosin in the blood plasma throughout the day between doses.

The drug is absorbed in the intestine, absorption is approximately 57% of the dose received. Food does not affect absorption.

Tamsulosin has linear pharmacokinetics. After a single dose of 0.4 mg on an empty stomach, the substance reaches its maximum concentration after approximately 6 hours. An equilibrium state is achieved by the fourth day of taking the drug, with the highest concentration of tamsulosin in plasma reaching 4–6 hours after administration (on an empty stomach or after a meal). The peak plasma concentration compared to the first dose (6 ng/ml) at steady state increases to 11 ng/ml.

The lowest plasma concentration of the drug is 40% of the maximum plasma concentration after administration on an empty stomach or after a meal. The potential for individual patient differences in tamsulosin concentrations after a single dose or multiple doses should also be considered.

Omnic Okas is characterized by high binding to plasma proteins (about 99%) and a small volume of distribution (about 0.2 l/kg).

Tamsulosin is metabolized slowly in the liver to form less active metabolites. However, most of the drug is presented in unchanged form in the blood plasma.

According to experimental data, tamsulosin has virtually no ability to induce the activity of microsomal liver enzymes, so dose adjustment is not required for patients with liver failure.

The drug and its metabolites are excreted mainly in the urine, only 4-6% - unchanged.

The half-life (T½) is 19 and 15 hours with a single dose and at steady state, respectively.

The principle of action of the medication

When taken orally, Omnic is absorbed in the intestine. Eating food beforehand can slow down the absorption process. To ensure uniform absorption of the drug throughout the course of treatment, the doctor may advise using Omnic daily after the morning meal. The equilibrium concentration of tamsulosin in the patient’s blood is achieved by the fifth day of administration.

In patients with impaired renal function, the dosage of the drug is not reduced. Caution must be exercised when prescribing tamsulosin to persons whose creatinine clearance is less than 10 ml per minute. Omnic adrenergic blocker capsules are placed in blisters. Each factory package contains 1 or 3 blisters. The blister contains 10 capsules. Each capsule contains a daily dose (0.4 g) of the active substance - tamsulosin hydrochloride.

Damage to the capsule in the oral cavity affects the metabolism of the active substance in the body, so the capsules must be taken whole, without chewing. Capsule size No. 2, the body is orange in color, with the number 701 printed on it. The lid is painted in an olive tint. The dosage of tamsulosin is 0.4 on the cap. Whitish granules are clearly visible inside the capsule.

Modified-release capsules contain the following inactive ingredients: microcrystalline cellulose, methacrylic acid type C copolymer, sodium lauryl sulfate, polysorbate 80, gelatin, triacetin, calcium stearate, talc, titanium dioxide, indigotine, iron oxides (red and yellow).

Omnic: a course of treatment for various diseases

Fast and effective action, long-lasting effect of therapy - these are the main characteristics of the drug Omnik. How to take this medicine correctly? First of all, you should remember that the capsule of the drug cannot be broken. This can damage the modified Omnic release and compromise all healing. If the question is whether to take the drug in the morning or in the evening, then there is only one answer - the time to take the medicine should be in the morning. Moreover, the capsule should be taken after breakfast or the first meal. Even if the patient ate an apple before breakfast, he must take medication immediately afterward.

How many Omnic capsules to drink per day does not depend on the disease or the nature of its course. 1 capsule once a day is a universal treatment regimen with Omnik. The duration of treatment depends on the disease and its severity. The duration of taking the medication is determined only by the attending physician, based on the medical history, laboratory tests and the individual characteristics of the patient.

The difference between Omnic and Omnic Okas

Having seen two similar names, patients are often confused and cannot decide which drug the doctor prescribed for them. And they also wonder what are the differences between the drug Omnic and Omnic Ocas? What is the price, analogues, reviews?

It's simple: the differences between Omnic and Omnic Okas are only in the absorption and distribution of the drug in the body.

In other words, Omnic Okas usually has a milder effect on the body as a whole and on lowering blood pressure in particular, which is optimal for hypotensive patients. Thanks to the special coating of the tablets, the active component is released slowly and affects the body for 24 hours, while the Omnic product acts quickly and completely, immediately after the capsule shell dissolves.

This means that Omnic Okas is intended for people suffering from problems such as moderate hypotension, diabetes mellitus, liver and kidney failure, or having other chronic diseases for which the drug should be used with caution. Otherwise, the principle of action of the product and its composition are absolutely identical, both in the number of components and in name

If we consider both drugs in terms of the number of side effects, then preference should be given to the new form of release of the drug. The difference between Omnic and Omnic Ocas is the form of release: the first medicine is available in capsules, the second - in small tablets. It can also be noted that Omnic Ocas can be used in any time of the day or night, regardless of food intake.

Omnik Okas

Another difference between the two drugs is that Omnic is most often prescribed for advanced stages of the disease, Omnic Okas - for the chronic form of adenoma, aggravated by dysuric symptoms. The price range is also important when purchasing a medicine. This is another difference between medicines.

Omnic Okas reduces blood pressure less frequently than its previous analogue, which is an undeniable advantage for some patients experiencing problems with blood pressure. Which drug is better and what is their special difference can only be noticed by patients who have been taking drugs for a long time. Cure diseases of the genital area, prostatitis , difficulty urinating, or benign prostatic hyperplasia, is currently an expensive pleasure.

Contraindications

Do not drive while taking this medication.

The drug has only four absolute contraindications:

• intolerance to the active substance;
• history of angioedema;
• orthostatic hypotension;
• severe form of renal failure.

In mild forms of kidney dysfunction, the drug can be taken, but under the supervision of a doctor.

Since the drug can cause a decrease in blood pressure, which negatively affects concentration, it is recommended to refrain from driving during treatment.

The drug cannot be combined with other drugs of similar action, as this enhances the antihypertensive effect, which can lead to symptoms of low blood pressure - drowsiness, loss of strength, dizziness, confusion.

Description of the medicine

The dosage is selected individually for each patient and depends on the symptomatic picture of the disease.

Today, Omnik for prostatitis is a first-line drug of choice, but does not affect the inflammatory process in the prostate, therefore it is used as part of symptomatic therapy.

The main active ingredient is tamsulosin. The medicine is available in long-acting capsules, each containing 0.4 mg of active ingredient. Modified release of the active substance allows you to take just one capsule of the drug per day while maintaining the therapeutic effect throughout the day.

The main function of the drug is to facilitate the process of urination. In this regard, it is prescribed only if the patient has problems emptying the bladder.

The medicine is characterized by rapid action, the effect occurs the very next day after taking the first therapeutic dose. However, due to the specific nature of the action, it is necessary to take the drug in a course, the duration of which is determined by a urologist, depending on the manifestations of the disease in a particular man.

The product is available by prescription, so you should consult your doctor and take the drug only as directed.

Mechanism of action

The medicine belongs to the selective alpha-1 adrenergic receptor blockers. These receptors transmit nerve impulses to the smooth muscles of organs and blood vessels, causing them to contract and increasing their tone. As a result of the activity of these receptors, the tone of the bladder and prostate increases, which leads to problems with urination and dysuric disorders.

The active substance of the drug blocks the activity of these receptors, preventing them from responding to appropriate signals. The selective effect of the drug allows you to influence only the bladder, urethra and prostate, without a general effect on all vessels of the body. The result is complete emptying of the bladder and normalization of urodynamics, which reduces discomfort and accelerates the overall recovery of the prostate.

Body reaction

Slight general lethargy and drowsiness may occur

Having figured out why Omnic is prescribed for prostatitis, you should know exactly how it acts on the body. The drug promotes:

• decreased tone of the prostate gland;
• reducing bladder spasm;
• relaxation of urethral vessels;
• decreased tone of the lower part of the urethra.

As a result, the prostate stops squeezing the neck of the bladder and the feeling of its constant fullness disappears.

The next effect of taking the medicine is easier emptying of the bladder. If before taking the drug a man was forced to strain his pelvic floor muscles in order to urinate, after several days of regular use of the drug this need no longer exists. As a result, the urination process is normalized, spasms and pain in the bladder and prostate disappear, and urodynamics improve.

In the treatment of prostatitis with Omnik, an integrated approach is necessary, since this drug does not affect the inflammatory process in the prostate gland. The drug is used only to eliminate the unpleasant symptoms of dysuric disorder.

The capsules act quickly and are almost 100% bioavailable. They are coated with an enteric coating, so they effectively penetrate the tissues of the prostate gland and bladder.

The active substance is released slowly, providing round-the-clock control of organ tone. However, Omnic is far from safe and is quite difficult for the body to tolerate, causing systemic side effects.

Despite the selective effect, the drug still has some relaxing effect on the blood vessels, thereby causing a slight decrease in pressure. This is not dangerous for a healthy person, but in some men it can cause weakness and dizziness.

Omnic: for what and for what diseases is it used?

Since frequent urination is observed not only with BPH, the drug Omnik is used:

• for prostatitis, including chronic prostatitis;
• for prostate cancer;
• with stones in the ureter;
• with urolithiasis;
• with cystitis;
• with prostate adenoma;
• with an overactive bladder;
• with congestive prostatitis;
• for kidney stones;
• with urinary incontinence;
• with a neurogenic bladder;
• for oncology;
• with acute urinary retention;
• with renal colic;
• with urethritis.

The drug Omnic has a comprehensive effect on the pathology of the genitourinary system. It not only relaxes the smooth muscles of the bladder, urethra and prostate, but also has an anti-inflammatory effect and reduces the rate of progression of the disease as a whole.

pharmachologic effect

Omnic selectively and competitively blocks postsynaptic β1A-adrenergic receptors located in the smooth muscles of the prostate gland, bladder neck and prostatic urethra, as well as β1D-adrenergic receptors, mainly located in the body of the bladder. This leads to a decrease in the tone of the smooth muscles of the prostate gland, bladder neck and prostatic urethra and improved detrusor function. This reduces the symptoms of obstruction and irritation associated with benign prostatic hyperplasia. As a rule, the therapeutic effect develops 2 weeks after starting the drug, although some patients experience a decrease in the severity of symptoms after taking the first dose.

Omnic's ability to act on 1A-adrenergic receptors is 20 times greater than its ability to interact with 1B-adrenergic receptors, which are located in vascular smooth muscles. Due to such high selectivity, the drug does not cause any clinically significant decrease in systemic blood pressure in both patients with arterial hypertension and in patients with normal baseline blood pressure.

Overdose

Symptoms of overdose are most often expressed in the formation of compensatory tachycardia and a decrease in blood pressure.

In order to prevent further absorption of tamsulosin, it would be advisable to carry out measures aimed at cleaning the gastrointestinal tract (enema, gastric lavage), as well as internal administration of sorbents. The patient's heart rate and blood pressure can recover independently when he assumes a horizontal position. If this method is ineffective, the use of medications that increase blood volume should be considered, and, if necessary, vasoconstrictors should be prescribed.

Urologist: Alexander Bondarchuk - positive review

Omnic is a drug that was created by the manufacturer to normalize the process of urination during prostate hyperplasia . This disease is characterized by difficulty urinating and, accordingly, pain symptoms. In the absence of proper treatment, hyperplasia develops quickly, as a result of which a person experiences a complete delay in urges - a serious pathology that causes severe spasms.

I believe that Omnic prevents the development of this disease: it suppresses the growth of hyperplasia, facilitates the process of emptying the bladder and normalizes the patient’s general well-being. I recommend taking the product after a full medical examination and as prescribed by a doctor.

Urologist: Andrey Derevyalov - positive review

Omnik effectively restores painless urination, reducing the number of urges to empty the bladder per day. It slows down prostate growth and hyperplasia , fights bacteria and reduces inflammation. I recommend taking this drug during complex therapy for benign hyperplasia and using it for at least two weeks. It is after this period that the first clinical results of therapy appear.

Omnic has contraindications, the main ones being:

liver, kidney failure;

Before therapy, it is important to exclude the presence of other diseases, the symptoms of which can be confused with signs of hyperplasia.

Source apv-men.ru

Among the diseases in men, the most common is benign hyperplasia (that is, enlargement) of the prostate gland and its inflammation (prostatitis). This disease is very unpleasant and causes discomfort to a man. An enlarged prostate interferes with normal urination, causing the patient to go to the toilet frequently. Moreover, every act of urination is painful and unpleasant. Also, with benign prostatic hyperplasia (BPH) and prostatitis, erection is impaired, which leads to problems in a man’s sexual life. It is for these reasons that it is so important to detect this disease in time and begin to treat it.

Today, the best medicine for BPH and prostatitis is Omnic. The drug contains the active component tamsulosin hydrochloride, which affects receptors in the prostate gland and bladder. Why is this medicine needed and what effects does Omnic have?

The effect of tamsulosin on the main links in the pathogenesis of benign hyperplasia

The active component of the medication for the treatment of prostatitis is absorbed into the gastrointestinal tract in the first minutes after taking the medication. This indicates its 100% bioavailability. Experts note that after eating food, the absorption of medicinal substances slows down slightly. It is recommended to take Omnik for prostatitis after meals. Thanks to this, it will be possible to increase the effectiveness of the drug.

After the first capsule of the drug enters the body of a patient with prostatitis, after 6 hours the maximum concentration of the main component of Omnic reaches 400 mcg. It binds 100% to plasma proteins.

6 hours after administration, the maximum concentration of the main component is reached

The active substance of the antibacterial drug enters the liver. In this organ it forms inactive metabolites. However, most of the component still ends up in the blood in the form in which it entered the body.

Over time, the drug will be excreted from the man’s body along with urine. In this case, about 9% of tamsulosin will remain in its original form. Complete removal of the contents of the capsule will be observed no earlier than after 10 hours. This is provided that it is taken once. Long courses of treatment increase the elimination time to 13 hours.

Tamsulosin is absorbed in the small intestine, and if the drug was taken on an empty stomach, it is absorbed by the body after 4-5 hours, and if on a full stomach, after 6-7 hours.

The bioavailability of Omnic is over 90%, and to achieve an equilibrium concentration of the drug in the body it is necessary to take it without interruption for 5 days.

And only after this does the pronounced therapeutic effect of the medicine occur. However, not only skipping a dose can become an obstacle to establishing equilibrium concentrations, but also different times for drug absorption on different days.

Therefore, the manufacturer recommends taking the capsules daily at the same time in the morning, after your usual breakfast. It is advisable to take the capsules with plenty of water.

During treatment with Omnik, you must adhere to a diet and eat a healthy, balanced breakfast every day before taking the drug.

Omnic selectively affects alpha 1-adrenergic receptors concentrated in the neck of the bladder, prostate gland, and prostatic part of the urethra. The drug relaxes the smooth muscle fibers of the prostate gland, normalizes urination, and reduces the severity of obstructive symptoms. As a result, the patient notices increased urine flow.

Omnic acts on the bladder wall, reducing the level of detrusor hypertrophy and normalizing elasticity. Thanks to this, irritative symptoms decrease, the urge to urinate becomes less frequent and painless.

Since Omnic has virtually no effect on adrenergic receptors located outside the pelvis (in the vascular walls), the severity of undesirable effects is minimized. Urologists prescribe tamsulosin to elderly patients and people who need to take other drugs from the group of adrenergic blockers (for example, for hypertension). Omnic is indicated not only for normal blood pressure values, but also for hypotension.

Comparison of prices for analogues within the same pharmacy

In different pharmacies, prices for the same drug vary greatly, so we offer Omnic Ocas analogues from other companies containing 0.4 mg tamsulosin in one tablet or capsule, which are displayed in the windows of one establishment. The cost of drugs is constantly changing, so the figures are provided for comparison purposes only, so that when trying to replace an expensive drug, men know what to look for.

This is a small part of the list of drugs containing tamsuzolin 0.4 mg, which is most in demand and is constantly sold according to doctors’ prescriptions for the treatment of prostate adenoma and prostatitis in acute form.

For comparison, next to the listed medications is Omnik, the Netherlands, the packaging of which costs 375 rubles for 10 capsules or 859 rubles for 30 pieces.

“Proflosin” “Tamsulosin” “Fokusin”

Manufacturers from the Russian company Vertex offer a similar extended-release drug Tamsuzolin for 385 rubles per pack of 30 capsules. Omnic capsule analogues are cheaper only than those made in Russia, up to 300 rubles, but now they are extremely difficult to find in pharmacies. On the shelves there are mainly drugs produced in the Netherlands.

Omnic okas is characterized by controlled release and gradual entry into the blood. Its purchase is justified for patients with prostate adenoma with unstable blood pressure and a weak heart. A drug with a milder effect is recommended for older people with age-related changes in the liver and prostate gland.

What to do if Omnik doesn’t help?

If Omnic does not help, contact your doctor. Perhaps you are taking the drug incorrectly, its dosage is too low, or Omnik is simply not suitable for you. Only the attending physician can decide what to do if Omnic does not help.

The drug Omnic is an effective drug for the treatment of benign prostatic hyperplasia (BPH) and prostatitis. Omnic is well tolerated by the body and rarely causes adverse reactions. This medication has its advantages and disadvantages.