TABLETS FOR THRUST PIMAFUTSIN reviews from doctors, negative and real, scam or truth, price in the pharmacy for 2020 22:05

Compound

The suppository contains natamycin as an active ingredient. Additional components include: cetyl alcohol , adipic acid , solid fat, sorbitan trioleate , polysorbate 80, sodium bicarbonate.
Pifamucin ointment. The main component is natamycin . Auxiliary components: propylene glycol, cetostearic alcohol, sodium lauryl sulfate, purified water, decyl letate, methyl parahydroxybenzoate, cetyl wax ether, propyl parahydroxybenzoate.

Pifamucin tablets. The active ingredient in the tablets is natamycin , auxiliary ingredients: kaolin, white beeswax, polyvinylpyrrolidone , titanium dioxide, sucrose, magnesium stearate, kaolin, methyl parahydroxybenzoate, gelatin, gum arabic, potato starch, calcium carbonate, lactose, triacetin.

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Pharmacodynamics and pharmacokinetics

The principle of action of the drug is based on the binding of sterols in the cell membrane, violating their integrity, which causes the death of the microorganism. The drug affects yeast-like fungi (especially Candida albicans), yeast , dermatophytes , pathogenic fungi .

Natamycin is active when used topically, has no systemic effect, and is not absorbed through mucous membranes or skin. The enteric coating of the tablets determines the effect of the drug in the intestines.

Indications for use

Pimafucin cream is prescribed for fungal infections of the nail plates, skin and mucous membranes, including vulvovaginitis , balanoposthitis , vulvitis , vaginitis , ringworm , otitis media caused by fungi or complicated by candidiasis, candidiasis of the nails and skin .

Pimafucin tablets are effective for fungal diseases of the external auditory canal, mucous membranes, and oral cavity. It is prescribed for intestinal candidiasis , after therapy with corticosteroids , antibiotics , cytostatics , vulvovaginitis , vulvitis , vaginitis , acute atrophic or pseudomembranous candidiasis with cachexia .

Pimafucin suppositories are prescribed for balanoposthitis , vulvovaginitis , vulvitis , vaginitis caused by Candida fungi.

Pimafucin for thrush in men

It is reliably known that genital mycosis affects not only women, but also members of the stronger sex. Candidal balanoposthitis, or male thrush, occurs under the influence of active reproduction of fungi of the genus Candida. The disease is characterized by inflammation of the head of the penis and the surrounding foreskin. An antifungal antibiotic eliminates the negative manifestations of mycotic lesions and promotes the death of pathogenic agents.

Composition and release form

The active component of the drug is natamycin. This substance belongs to the group of polyenes - antimycotic agents of natural origin. The antibiotic natamycin is effective against yeast-like fungi and dermatophytes. In addition to the main substance, Pimafucin contains auxiliary components. The final composition of the drug depends on the intended form of its release:

• Pimafucin 100 mg n20 tablets, enteric-coated;
• Pimafucin cream (ointment), tube 30 g.

How the drug works

The active substance Pimafucin irreversibly binds to the sterols of fungal membranes, disrupting their structure. The Natamycin molecule, penetrating the cell membrane of the pathogen, forms many small tubules through which the uncontrolled movement of water and electrolytes then occurs. Against the background of these processes, the fungus loses resistance to negative external influences and dies. Natamycin is not able to penetrate into the systemic bloodstream through the mucous membranes, skin, and gastrointestinal tract - the drug has an exclusively local effect on the affected area.

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Indications for use

The medication is intended for the treatment of fungal diseases caused by microorganisms sensitive to natamycin. The use of one or another form of the drug is determined by the intensity of the clinical manifestations of infection and the localization of the infectious focus. Pimafucin tablets are used for systemic treatment of intestinal candidiasis and external genitalia in men, while natamycin ointment (cream) is prescribed for the following conditions:

• dermatomycosis;
• skin candidiasis;
• balanoposthitis;
• fungal infection of the urethra.

Instructions for use of Pimafucin (Method and dosage)

Pimafucin suppositories, instructions for use. Used intravaginally. For vulvovaginitis , vulvitis and vaginitis , 1 suppository is administered for 3-6 days. It must be administered in the “lying down” position, as deeply as possible, before bedtime, once a day. If treatment of vaginitis does not help, then you should take tablets - 10-20 days, 1 tablet four times a day. For men, use cream during treatment. The duration of treatment is determined in each case individually. After the symptoms of the disease disappear, treatment should be continued for several more days.

Instructions for the cream. For external use. The ointment should be applied to the affected areas one to several times a day for balanoposthitis , vulvovaginitis and vulvitis . If symptoms persist, suppositories or tablets are prescribed. For dermatomycosis (including diaper rash in children and candidiasis of the nails and skin), the suspension should be applied to the nails and skin up to 4 times a day.

For mycosis of the external auditory canal, the affected area should be lubricated with cream up to four times a day, after cleaning the ear. After use, it is necessary to place a turunda made of cotton or wool into the ear canal. The duration of treatment is determined individually. After the symptoms completely disappear, it is necessary to continue treatment for several days.

Instructions for use of tablets. For intestinal candidiasis, are prescribed 1 tablet four times a day, children - 1 tablet twice a day. On average, the course of treatment lasts a week.

Pimafucin will help with fungal infections

Pimafucin is a drug widely used to treat fungal infections that are caused by yeast or yeast-like fungi. The drug is used for all groups of patients (men, women and children), most often in obstetrics, gynecology, general therapy and dermatovenerology.

Brief description of Pimafucin

The main active ingredient in Pimafucin is a broad-spectrum antibiotic from the group of macrolides (polyene series) natamycin. The main mechanism of action is the binding of sterol groups in the cell membrane, which leads to its damage, disruption of exchange with the environment and death. Main spectrum of action:

• Yeast-like fungi (especially Candida alb.)
• Dermatophytes (Microsporum, Trichophyton, Epidermophyton)
• Torulopsis, Rhodotorula – yeast
• Microorganisms of the Aspergillus and Penicillium groups

Approximate price of the drug

Excipients:

• Tablets (talc, potato starch, lactose, gelatin, etc.)
• Suppositories (polysorbate, cetyl alcohol, solid fat, etc.)
• Cream (organic alcohols, cetyl wax ester, purified water, etc.)

(Japan).

Indications for use of Pimafucin

• Acute and chronic vaginal candidiasis
• Prevention of thrush recurrence
• Prevention of repeated fungal infections of the vagina that develop with primary or secondary immunodeficiency or long-term use of antibiotics that disrupt the bacterial landscape of the vagina
• As part of complex therapy of systemic fungal diseases

Contraindications

Contraindications to Pimafucin are few and consist of intolerance (allergy) to the components of the drug (even in the past).

Side effects

Pimafucin is usually well tolerated; cases of overdose are extremely rare.

In rare cases, the drug may cause local reactions (itching, redness, burning, slight swelling of the genitals)

When using local form (cream, suppositories): nausea, vomiting, diarrhea (at the beginning of treatment), which disappear with further use of the drug.

special instructions

During treatment, it is recommended to completely avoid sexual activity. During unprotected sexual intercourse, the medicine can cause local allergic reactions to the skin of the genital organs of the sexual partner. The use of condoms or a diaphragm - there is a decrease in their contraceptive properties.

Dispensed from a pharmacy with a doctor's prescription

Shelf life: 2 years in a dark place away from children.

Doesn't cause addiction.

Method of using Pimafucin for thrush

In the treatment of acute candidiasis vulvitis and vulvovaginitis, the following is used:

• Suppositories (1 suppository is inserted deep into the vagina 1 time per day before bedtime; the course of treatment is determined by the doctor, but on average the duration is 3-6 days)
• Cream (can be used in conjunction with candles). Depending on the clinical picture, apply one to four times a day for 10-14 days

The treatment tactics consists of two stages: clarification of the main cause of the disease, risk factors for its development - first, second - the appointment of Pimafucin is possible only in complex therapy. In this case, the use of systemic antifungal drugs, for example, Pimafucin tablets, is added to the treatment regimen. Typical dosage: 1 tablet 4 times a day for 10-18 days together with the introduction of suppositories or the use of cream (see above). In rare cases, a systemic drug is replaced with another group of drugs (for example, Pimafucin tablets are replaced with the tablet form of Fluconazole).

When treating chronic thrush, treatment regimens, duration of treatment, and combinations of medications are determined solely by the doctor.

Pimafucin's analogs

Pimafucin analogues: Primafungin.

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special instructions

Under the influence of body temperature, vaginal suppositories quickly dissolve, forming a foamy mass, due to which the active substance is distributed evenly. For recurrent or chronic infections, therapy can be supplemented with cream or tablets.

Cetyl alcohol, which is part of the suppositories, can cause a burning sensation in the genital area. Candle therapy should be interrupted during menstruation. During treatment with suppositories, sexual intercourse may not be excluded. However, both partners should be examined, and if a lesion is detected, Pimafucin cream for men should be used. Treatment with ointment for men occurs in the manner prescribed by the instructions. When having sexual intercourse during treatment, barrier contraceptives should be used.

It is possible to prescribe Pimafucin to newborns.

Contraindications, side effects and special instructions

The product is well tolerated and therefore has a minimum of contraindications. This also concerns the development of side effects: they accompany treatment with Pimafucin in rare cases, therefore the drug is recommended during gestation, breastfeeding and in childhood.

Individual intolerance to the component composition of the drug is considered as the main contraindication.

In rare cases, a local reaction occurs. Its manifestations are:

• redness;
• burning;
• itching;
• swelling.

If symptoms of an allergic reaction develop, treatment should be stopped and a doctor should be consulted to change the medication.

Important! Treatment of partners when vaginal candidiasis is detected in a woman should be joint. Otherwise, the cure for the disease will be significantly delayed, since the woman will become infected again during the next sexual intercourse.

A man is recommended to use the cream during unprotected sexual intercourse with a sick woman. The drug in this case is a means of prevention.

Pimafucin's analogs

Level 4 ATC code matches:
Nystatin

Colistin

Alpha Normix

Analogs of tablets: drugs Alpha Normix and Nystatin-Health .

Analogues in the form of suppositories: Nystatin , Livarol , Clotrimazole . The price of analog candles is from 37 to 320 rubles.

Pimafucin has a cheaper analogue - Nystatin , a domestically produced drug, similar in action.

Clotrimazole or Pimafucin - which is better?

Clotrimazole is available in the form of suppositories and cream. The course of treatment usually lasts about a week, the drug is well tolerated, which reduces the risk of side effects to a minimum. However, it may cause allergic reactions to any of its components. If the disease is detected in a woman, thrush ointment for men is used. According to experts, Pimafucin is more effective when used topically and it almost does not enter the systemic bloodstream. Therefore, it can also be used to treat pregnant women.

Which is better: Terzhinan or Pimafucin?

Terzhinan is produced in the form of vaginal tablets; it can be prescribed not only in the presence of the disease, but also for its prevention. The average duration of drug treatment is 10 days. It is also easily tolerated and can be used before childbirth.

Pimafucin or Fluconazole - which is better for thrush

Manufacturer: Biocom, Vertex, Russia/Polpharma, Poland
Release form: capsules

Active ingredient: Fluconazole

Synonyms: Diflucan, Diflazon, Mikomax, Mikosist, Mikoflucan, Flucostat

Fluconazole is the most common analogue of Pimafucin in the form of tablets for thrush.

For mild thrush, a single use of a 150 mg capsule is sufficient.

For complex treatment, it is optimal to use vaginal suppositories of Pimafucin with one capsule of Fluconazole orally.

Pimafucin during pregnancy and lactation

There are no contraindications for taking the drug for pregnant women or while breastfeeding. Tablets, creams and suppositories are used for thrush both in the early stages of pregnancy and in later stages. Most often, Pimafucin suppositories are prescribed during pregnancy, rather than other forms of this medicine. The drug is non-toxic and safe for the fetus both during the 1st trimester and 2nd trimester, as well as during lactation. However, to minimize the risk, it is better to take suppositories during lactation, or cream. Use of the drug is as indicated in the instructions.

pharmachologic effect

Manufacturer: LEO Pharma, Denmark/Astellas, Netherlands
Release form: enteric tablets, cream for external use, vaginal suppositories

Active ingredient: Natamycin

Synonyms: Primafungin, Ecofucin

The active substance of Pimafucin is an antibiotic of the macrolide group, to which most pathogens of fungal diseases are sensitive - yeast and mold fungi, including Candida, Aspergillus, as well as the protozoa Trichomonas.

When enteric tablets are taken orally, the antifungal effect occurs locally in the intestinal lumen.

The drug is not absorbed through intact skin and mucous membranes, so it does not have a systemic effect.

Reviews about Pimafucin

On the forums, the overwhelming majority of patients report a positive effect after using the medicine. However, there are cases when there is no improvement in the condition or it even worsens. There are also claims about the short-term effect of treatment for thrush and other diseases.

Pifamucin for thrush , according to patients, helps by quickly eliminating its symptoms. Moreover, the cream is effective for both women and men. Pimafucin tablets for thrush also help in the treatment and prevention of candidiasis.

Reviews about the tablets are most often good; patients write about the fast and effective action of the medicine and the complete absence of side effects. Reviews of Pimafucin suppositories for thrush report that they relieve itching faster than when taking tablets, as they act locally. There are no negative reviews about Pimafucin cream; it helps well with fungal diseases and is easily tolerated. Most often, the ointment is prescribed to men. Positive reviews during pregnancy note that the drug does not affect the development of the fetus and is very well tolerated, quickly eliminating the disease.

Pimafucin or Clotrimazole - which is better for thrush

Manufacturer: Green Dubrava, Ozone, Synthesis, Russia/GlaxoSmithKline, Poland
Release form: cream and ointment for external use

Active ingredient: Clotrimazole

Synonyms: Candide, Clotrimazole Teva, Clotrimazole-Acri

The analog Clotrimazole is used in the form of a cream for men and vaginal tablets for women for various female fungal diseases, including thrush. During pregnancy, especially in the first trimester, it is better not to use Clotrimazole.

Clotrimazole is a cheaper analogue of Pimafucin cream, so it can be used as a replacement for various candidiasis.

Pimafucin price, where to buy

The price of Pimafucin cream in Ukraine is 87 UAH, in particular in Kharkov the ointment costs about 81 UAH.

In Russia, the price of Pimafucin tablets is 360 rubles, in Belarus the cost of the medicine in tablets is 133.5 thousand rubles.

The price of Pimafucin suppositories for thrush is 270-380 rubles. In Odessa, candles No. 3 cost 123 UAH, candles No. 6 – 213 UAH.

You can find out how much the suppositories cost and buy other forms of the drug directly at the pharmacy.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Pimafucin vaginal suppositories.
  100 mg 6 pcs Temmler Italy S.r.L. RUB 467 order
• Pimafucin vaginal suppositories. 100 mg 3 pcs Temmler Italy S.r.L.

  RUB 236 order

• Pimafucin cream 2% 30g Temmler Italy/Astellas

  RUB 374 order

• Pimafucin tablets p.p.o. enteric solution 100 mg 20 pcs. Astellas Pharma Europe B.V.

  RUR 541 order

Pharmacy Dialogue

• Pimafucin vaginal suppositories 100 mg No. 6 Temmler

  RUR 504 order

• Pimafucin cream (tube 30g)Temmler

  RUB 377 order

• Pimafucin (100 mg tablet No. 20)Astellas Pharma

  RUR 631 order

• Pimafucin vaginal suppositories 100 mg No. 3Temmler

  RUB 276 order

• Pimafucin vaginal suppositories 100 mg No. 3LEO/Temmler

  RUB 278 order

Europharm* 4% discount using promo code medside11

• Pimafucin cream 30 g Temmler Italy/Astellas

  430 rub. order

• Pimafucin vaginal suppositories 100 mg n6 Temmler Italy S.r.L.

  540 rub. order

• Pimafucin tablets 100 mg n20Astellas Pharma Europe B.V.

  670 rub. order

• Pimafucin vaginal suppositories 100 mg n3 Temmler Italy S.r.L.

  RUB 292 order

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Pharmacy24

• Pimafucin 100 mg No. 3 vaginal suppositories Temmler Italy S.r.l., Italy
  149 UAH.order
• Pimafucin 100 mg No. 6 suppositories Temmler Italy S.r.l., Italy

  287 UAH order

• Pimafucin 2% 30 g cream Temmler Italy S.r.l, Italy

  146 UAH order

• Pimafucin 100 mg N20 tablets Astellas Pharma Europe B.V., Netherlands

  431 UAH. order

PaniPharmacy

• Pimafucin suppository Pimafucin vaginal suppositories 100 mg No. 6 Italy, Temmler Italia

  296 UAH. order

• Pimafucin tablets Pimafucin film-coated tablets 100 mg No. 20 Netherlands, Astellas Pharma Europe

  489 UAH. order

• Pimafucin cream Pimafucin cream 2% 30g No. 1 Italy, Temmler Italia

  169 UAH order

• Pimafucin suppository Pimafucin vaginal suppositories 100 mg N3 Italy, Temmler Italia

  166 UAH order

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Admission rules

The drug is not intended for self-medication. The duration of therapy for thrush is regulated by the doctor. Each form of medicine has its own subtleties of administration. For the use of medicine in childhood, the dose of the medicine is determined by the pediatrician.

Treatment in tablet form

How to take the medicine and in what doses should be determined by a specialist. But the standard dose indicated in the annotation for the medication for the treatment of persistent thrush is 100 mg or 1 tablet 4 times a day. The course must be at least 10 days, but not more than 20 days. Only a doctor can accurately determine the course of treatment.

Eating does not affect the activity of the drug in any way. Therefore, you can drink it regardless of whether the patient has had time to eat or not.

A peculiarity of its use is the need to extend the course of therapy for several days (2–3 days) after the disappearance of the main symptoms:

• Itching.
• Burning sensation.
• Pain during urination.
• Characteristic white-curdled discharge.

It is recommended to take the drug for a few more days to consolidate the effect. It is important that the symptoms actually disappear, and not that their intensity decreases. Stopping the medication against the background of apparent recovery entails a rapid return of thrush symptoms.

Treatment with local forms

Suppositories for thrush are the most popular remedy for combating this disease in women. The duration of course therapy is determined by the attending physician. The average course indicated in the annotation is 6 days. In most cases, this course is enough to eliminate the exacerbation of candidiasis. For the treatment of mild forms of vulvitis and vulvovaginitis, 3 suppositories are usually sufficient. In case of severe illness, the doctor may prescribe 9 suppositories for daily administration in combination with Pimafucin tablets.

Suppositories are convenient because they are administered once a day (at night). Suppositories are introduced in a lying position, after all the usual hygienic procedures. Girls under 16 years of age are advised to refrain from using vaginal suppositories, in general, Pimafucin in particular.

If fungal colonies appear on the external genitalia, a cream may be prescribed in addition to suppositories. It is applied several times a day (from 1 to 4) depending on the growth of fungal colonies.

The cream is used to treat balanoposthitis. The product is applied in the same way as for vaginitis. After the signs of the disease disappear, it is recommended to apply the cream for some time to consolidate the effect.

As for the cream, its use is permissible not only for fungus of the external genitalia. It is effective for otomycosis, fungal infections of nails, and diaper rash infestation with fungi in children. Before using the cream to treat the ear canal, it (the ear canal) must be thoroughly cleaned of earwax.