Strengthening the child's immunity
Amiksin for children is used in complex therapy for the treatment of viral diseases, but is not intended for prevention.
Therefore, it is very important to adhere to the basic rules to maintain the child’s immunity. Here are a few basic rules that are not so difficult for everyone to follow:
Hardening
Hardening (hydrotherapy) is a very effective method of increasing immunity and improving well-being (by increasing norepinephrine and beta-endorphin). Its positive effects have been confirmed by a huge number of studies. Both domestic and foreign. So in 2019, a scientific publication was published in the USA about the positive effects of hydrotherapy on the immune, cardiovascular, and pulmonary systems.
Hardening the child should begin gradually, preferably in consultation with a pediatrician. It is started very gradually and consistently and only if the child is completely healthy. Such water activities are carried out in the morning, the water temperature is reduced by 1 degree every day. The limit for children of primary school age: from +32 to +20, for older children – up to +15.
Sunbathing
Sunlight promotes the production of vitamin D, which is necessary for bone growth, strengthening the immune system and nervous system. If there is not enough sunlight, the pediatrician prescribes vitamin D supplements.
Balanced diet
For school-age children, it is very important to receive a balanced diet - at this age, the child spends a huge amount of resources on studying. Add stress here - and here you have a ready-made reason for decreased immunity and frequent illnesses
Unfortunately, not all parents manage to organize the ideal diet for their child. Firstly, at this age children are already selective in food, and secondly, there are a huge number of harmful temptations around - chips, crackers, sweets, etc.
But at the same time, nutrition is an important factor, because a lack of vitamins and essential microelements can lead to disturbances in metabolic processes, problems with the gastrointestinal tract, cardiovascular, nervous, and immune systems.
Below is a table with the main vitamins and their content in foods.
Vitamins | Products |
Vitamin A | carrots, cabbage, green parts of plants, liver, fish oil, milk, cream, butter, egg yolk. |
B vitamins | bran, nuts and grains, dairy products, apples, tomatoes, peas, beans, radishes, turnips, radishes, beef, fish, soybeans, yeast. |
Vitamin C | citrus fruits, cabbage, tomatoes, turnips, red peppers, black currants, parsley. |
Vitamin E | sunflower, corn and olive oil, liver, egg yolk, sprouted wheat, buckwheat, rice and other cereals, lettuce. |
Vitamin D | fish, liver, butter, milk. |
A pediatrician may prescribe medications to boost immunity that are suitable for children, for example, multivitamin complexes. If a child continues to get sick frequently, despite all preventive measures, then the causes of this condition should be clarified by a pediatric immunologist, having undergone appropriate examinations.
Treatment with the antiviral drug "Amiksin": dosage, how to take
The antiviral drug "Amiksin" has a pronounced immunomodulatory property due to the ability to induce (stimulate the production) of natural interferons, which adversely affect the viability of certain strains of viruses.
Can be used for children over 7 years of age and during pregnancy if indicated under the supervision of a physician. The dosage depends on the disease and the type of viral microflora that causes it. The duration of therapy is determined by the regimens developed by the manufacturer and should be based on control blood tests confirming the presence of viruses or their elimination. Next, we will consider the composition of the drug and its pharmacological effect on the human body. The article also provides some dosage regimens, daily and single dosages, indications and contraindications.
Dosage, composition and pharmacological action of the drug "Amiksin"
The chemical composition of "Amiksin" includes the main active ingredient tiloron, in some cases replaced by tilaxin, and auxiliary components, including those that form the film enteric coating of the tablet. On sale there may be contour cells in cardboard boxes or packaging in the form of cans. The manufacturer offers packaging of 6, 10 and 20 tablets. For the treatment of acute viral respiratory infection, a course of treatment consisting of 6 doses is sufficient. For long-term use in the treatment of herpes, hepatitis and cytomegalovirus infection, it is advisable to purchase packages containing 20 tablets.
A single dosage of Amiksin for an adult is 125 mg, which is exactly the amount of active substance contained in 1 tablet. A dosage of 60 mg is also available, most often it is used in pediatric practice to treat children.
The pharmacological effect of Amiksin is due to its ability to provoke increased production of globulins belonging to the primary response group (alpha and gamma). After entering the small intestine, tilorone is released, stimulating the ciliated epithelium, producing primary forms of inducer interferons. Then the active substance is actively absorbed into the bloodstream and binds to blood cells responsible for humoral immunity. These are all forms of neutrophils, T-lymphocytes, macrophages and granulocytes. When transported into hepatocytes, tilorone does not lose its ability to provoke liver structures to renew the resource of the primary immune response. This allows the active use of the antiviral drug “Amiksin” for all forms of viral hepatitis. Improvement in the patient's condition in acute forms is achieved after 4 weeks; in chronic conditions, liver transaminases begin to return to normal after 6-8 weeks of systematic treatment.
The immunomodulatory pharmacological action of Amiksin is based on stimulating the active production of such forms of leukocytes as suppressors and helpers in the bone marrow structures. The high effectiveness of treatment has been proven by clinical trials in the complex therapy of acute respiratory viral infections, hepatitis, herpes, cytomegalovirus infection, and influenza.
Dosage: how to take Amiksin for various diseases | |
Treatment of acute respiratory infections, acute respiratory viral infections and influenza | 1 tablet (125 mg) 1 time per day for 2 days, then the indicated dosage is given every other day for 4 days |
Prevention of acute respiratory infections, acute respiratory viral infections and influenza | 1 tablet (125 mg) 1 time every 7 days for one and a half months. Prevention should begin 3 weeks before the expected increase in the level of seasonal colds and influenza epidemics |
Therapy of herpes and cytomegalovirus infection | Taking the drug is similar to the treatment regimen for influenza, but the course duration is 40 days |
Treatment of viral hepatitis | Depending on the strain of the virus, the course of treatment takes from 4 weeks to 3 months. Take the drug 125 mg every other day. |
Taking Amiksin during pregnancy and for children
According to the attached leaflet, the use of the drug "Amiksin" during pregnancy and breastfeeding is strictly contraindicated.
However, there are situations when a threat to a woman’s health leaves the attending physician no choice but to take a risk and use antiviral therapy. We are talking primarily about pregnant women at risk with high titers of the hepatitis virus and complex readings of liver tests in a biochemical blood test. Elevated levels of transaminases and bilirubin indicate that the expectant mother's liver may not be able to cope with the increased load and hepatic coma may occur. Therefore, the woman is placed in an infectious diseases hospital and, under the control of the parameters of a general and biochemical blood test, antiviral therapy is provided. At home, without medical supervision, taking Amiksin during pregnancy is strictly prohibited. Especially when it comes to treating a cold.
"Amiksin" for children is used in the treatment of viral diseases only after the child reaches the age of 6 years. Contraindications may be insufficient physical development (weight deficiency), mental and mental retardation, allergic reactions. Taking Amiksin begins on the first day after the onset of severe symptoms of acute respiratory infections, acute respiratory viral infections, influenza, and herpes. If hepatitis is detected, therapy begins after the diagnosis has been clarified and the pathogen strain has been identified. In pediatrics, a dosage of 60 mg is used. The drug is prescribed in the morning after breakfast.
Treatment with "Amiksin" for herpes and other indications for use
Currently, Amiksin treatment is widely used for various viral pathologies, since the drug has a wide spectrum of action and tunes the immune system to detect and destroy various strains of this form of the pathogen.
"Amiksin" for herpes does not provide complete elimination of the pathogen, but allows you to achieve long-term remission without external manifestations and damage to the nerve structures of the ganglia. If there are appropriate indications, a course of 6 weeks is prescribed in the fall and spring. If typical symptoms, confirmed by laboratory tests, appear, therapy can continue for up to 3 months.
Other indications for use may include:
- prevention of seasonal colds, especially in children who have not been vaccinated against influenza and persons whose professional activities involve numerous contacts with other people;
- complex therapy for complications of acute respiratory viral infections, acute respiratory infections and influenza, such as pneumonia, bronchitis, tracheitis;
- increasing the immune response in the treatment of tuberculosis, depressed immunity, and candidiasis;
- treatment of serous meningitis, tick-borne encephalitis and other types of neuroinfections (intercostal neuralgia, herpes zoster, trigeminal neuralgia).
Side effects and contraindications for treatment with Amiksin
Side effects of Amiksin occur very rarely and are usually not an indication for discontinuation of the treatment regimen used. It is enough to reduce the dosage in order to reduce the negative effects.
Side effects include:
- unpleasant sensations along the small intestine (go away on their own 1.5 - 2 hours after administration);
- loose stools and decreased appetite may be present in the first 2 days when using large doses of the drug;
- a feeling of slight chills, body aches and an increase in body temperature to subfebrile levels in the initial stages of pharmacological action are due to an increased immune response;
- allergic skin reactions in the form of urticaria require additional prescription of antihistamines Suprastin, Tavegil, Claritin, Cetrin and others.
Contraindications for treatment with Amiksin include early childhood (newborn, toddler and preschool periods), low body weight in a child after reaching the age of 6 years, pregnancy (the drug is used only if there are serious, life-threatening indications for the woman), lactation period under condition of breastfeeding. Individual hypersensitivity and intolerance to tilorone may also occur.
Compatibility of "Amiksin" and alcohol, antibiotics and other drugs
The compatibility of pharmacological drugs should be taken into account when prescribing complex therapy.
Immediately it is worth mentioning that alcohol and alcohol, when taken simultaneously, can give a pronounced clinical picture of food dyspepsia.
Patients complain of pain in the abdomen, repeated loose stools and copious discharge of bile. In addition, alcohol, even in minimal quantities, completely eliminates the therapeutic effect of this drug. In the long term, there is a high probability of developing a toxic form of hepatitis and kidney failure.
There are no such instructions from the manufacturer for antibiotics and other medicines. Combined regimens of antiviral and antibacterial effects can be used. A drug such as Wobenzym significantly increases the effectiveness of such an effect.
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Mechanism of action of the drug
Amiksin begins to act immediately after taking the tablet orally: interferons begin to be produced in the intestinal epithelial cells. Absorbed into the body, the drug causes the synthesis of interferon in liver cells - hepatocytes, and then in blood cells: T-lymphocytes, neutrophils and granulocytes. The maximum concentration of the active substance in the body is observed 4-24 hours after taking the drug.
According to the manufacturer, Amiksin effectively stimulates bone marrow stem cells when the immune system in children is suppressed for the following reasons:
- lack of nutrition, vitamins and minerals;
- nervous stress;
- treatment with hormonal and chemotherapy drugs;
- chronic infections (ascariasis, frequent relapses of herpes);
- endocrine diseases (diabetes mellitus, hyperthyroidism).
In special types of leukocytes - B-lymphocytes - children's Amiksin increases the formation of immunoglobulins, which recognize and neutralize pathogenic viral particles. Immunoglobulins are carried throughout the body in the blood, penetrate into all biological fluids and create protection against viral attack.
Amiksin enhances the activity of macrophages - special protective cells that can capture and absorb substances that are foreign and toxic to the body. Amiksin has an anti-inflammatory effect, blocks the reproduction and growth of tumor cells. Children's Amiksin is quickly absorbed from the digestive tract and excreted from the body in urine and feces, undergoing virtually no changes in the body. The drug is not included in metabolic processes and does not accumulate in tissues and organs.
The drug Amiksin. Instructions
Amiksin is a modern antiviral and immunomodulatory agent that contains the active ingredient tiloron. When taken orally, tilorone is quickly absorbed from the digestive tract and begins to act within 4 hours. The drug induces the synthesis of all types of interferons (alpha, beta, gamma and lambda) in leukocytes and stimulates bone marrow stem cells, enhances antibody formation, reduces the degree of immunosuppression, and restores the ratio of T-suppressors and T-helpers.
Amiksin has proven its high effectiveness against viral infections: influenza and ARVI viruses. The antiviral mechanism of action of Amiksin is associated with inhibition of the translation of virus-specific proteins in infected cells, and as a result, the reproduction of viruses is suppressed.
The drug increases the body's overall resistance and is effective at any stage of the disease. Research has proven that Amiksin reduces the duration of the disease, eliminates severe catarrhal symptoms, and minimizes the possibility of complications after influenza and ARVI.
Mechanism of action, indications and contraindications
Tiloron
The drug has an effect in two directions. It stimulates the active production of interferon, which prevents the multiplication of the virus.
This provides relief from pathological symptoms.
It also helps strengthen the immune system, making the body more effective in fighting the disease. Due to this, the likelihood of relapse of the disease is reduced.
Amiksin is a non-toxic drug. If you follow the instructions, it is safe and does not lead to significant changes in the body. The form of the drug containing tilorone 60 mg is characterized by an even milder effect, due to which it is recommended for the treatment of viral diseases in children.
The use of any drug requires compliance with the instructions
It is very important to use Amiksin according to indications, since in other cases it will be useless and even harmful
This medicine is often recommended for preventive purposes to avoid contracting the flu or other infectious diseases.
Indications also include:
- herpes;
- flu;
- ARVI;
- chlamydia;
- hepatitis;
- cytomegalovirus infection;
- tuberculosis;
- infectious and allergic diseases.
In these cases, this medicine is used in combination with other drugs, which speeds up the results.
Amiksin 60 is considered a safe drug, but it has contraindications, due to which it has to be replaced with other medications.
It is prohibited to use it if it has the following features:
- pregnancy;
- children's age (less than 7 years);
- breastfeeding;
- intolerance to the composition.
If the drug is used in these cases, adverse effects may occur. Therefore, it is best when the medicine is prescribed by a specialist.
Video from Dr. Komarovsky about antiviral drugs:
Amiksin for ARVI: treatment at home
There are two types of therapeutic approaches in the treatment of colds - symptomatic and etiological. There are also basic rules: periodically ventilate the room, drink plenty of fluids.
Symptomatic treatment of ARVI includes:
- Decrease in temperature. First of all, patients pay attention to an increase in temperature, general weakness and “weakness.” This is an intoxication syndrome. The temperature should be reduced only when it rises above 38.5°C. For this, paracetamol or ibuprofen is used, these substances are all included in, for example, Theraflu or Coldrex (paracetamol), Maxicold (ibuprofen).
- Elimination of runny nose. Rinsing the nose with saline helps. Also in the first days (when the mucous membrane is too swollen and the nose is “pouring”), vasoconstrictor drops are suitable. They should be used for no more than 4-5 days (some advise even less). Since you can develop a dependence on them, there is no mention that they dry out the nasal mucosa. In the future, this can lead to another respiratory infection. Because mucus protects us from viruses, being a kind of barrier to the penetration of viruses into the body.
- Relieving sore throat. Lollipops (Strepsils). Sprays (Hexoral, Doctor Mom, Tantum Verde). Rinse (Carmolis, Miramistin). Hot milk and honey are excellent ways to cope with pain, scratching, and sore throat.
The second part of the treatment is etiological, aimed at eliminating the main cause of the disease - viruses. The use of Amiksin for children and adults is the etiological part of the treatment. Amiksin has high antiviral activity and activates 4 types of interferons within the first 24 hours after the start of treatment. The drug blocks viruses at all stages of infection.
Operating principle
A normally functioning immune system can independently fight pests coming from outside, stop their activity and prevent them from multiplying, affecting more and more healthy cells. In response to invading viral agents, the immune system begins to produce interferons of the required quality and quantity, which act as human protectors from infection.
However, strong immunity today is a rarity; the ability of this system to protect the body is fully influenced by a number of factors:
- person's age;
- presence of chronic diseases;
- bad habits;
- individual characteristics.
When the immune system does not work fully, which is often observed in childhood, when it is just going through the stage of its intensive development, immunomodulators come to the rescue. Amiksin for children is one of the most effective drugs classified in this group.
This medication differs from other similar ones in that it has the ability to stimulate the production of not one, but three different types of interferons, therefore a high level of its effectiveness is achieved in relation to various pathogens of viral infections.
Amiksin is a traditional treatment for viral and bacterial infections that affect the respiratory system. In addition, it is used for preventive purposes, to prevent infection of a child or adult during a surge in morbidity among the population.
The main active ingredient of Amiksin is tilorone, which belongs to the category of endogenous interferon inducers. The latter is an important biological compound produced by immune cells to protect the body from viruses.
Tiloron has the ability to cause the following effects:
- production of additional amounts of interferons;
- suppression of viral translation in the cellular structure of the human body;
- stopping the process of pathogen reproduction;
- destruction of pathogenic microorganisms.
After therapeutic doses of tilorone are accumulated by the body's cells, the process of interferon production begins. This work is carried out by intestinal cells, liver cells, granulocytes and T-lymphocytes.
Amiksin has the ability to stimulate the creation of immunity against most viruses, so it can be used against various infections.
The medication has some other effects necessary to strengthen the activity of the immune system:
- Enhanced antibody production through the work of B lymphocytes and plasma cells.
- Stimulation of bone marrow stem cells, which is necessary for an increased number of immune cells in the blood serum.
- Optimization of the number of lymphocytes of types B and T, which allows the cells to be endowed with the maximum possible protective properties.
Tiloron, the main component of Amiksin, immediately after oral administration, undergoes absorption into cells through penetration through the intestinal walls. The concentration of the substance necessary to achieve a therapeutic effect is achieved in the body within half an hour after taking the medicine.
Tiloron has the ability to penetrate all barriers of the human body, including the blood-brain and placental ones. Its presence can be detected in breast milk, blood, plasma, and tissues.
The active substance is excreted outside the body almost unchanged, most of it in feces, the rest in urine. The half-life of the drug is 2 days.
Action of Amiksin
The current classification of drugs classifies tilorone as immunomodulators and antiviral drugs. This chemical compound is able to fight an existing infection and prevent the development of the disease by affecting the body's defense systems. The active component is absorbed in the digestive tract, enters the bloodstream and stimulates the functioning of cells that produce interferon. There is increased activity of tilorone against intestinal epithelial cells, leukocytes and hepatocytes.
Amiksin packaging
Interferons are natural components of human immunity. These are protein compounds produced by tissues in response to the development of infection. Different types of this substance suppress viral replication. Drugs that improve the production of interferons are called immunomodulators.
Antibiotics are not suitable for treating viral infections. These drugs destroy bacteria, but do not suppress the development of viral particles. Mechanisms of indirect effects on immune functions have recently been discovered. New classes of safe drugs have emerged. Interferon inducers do not suppress healthy intestinal microflora and do not contaminate tissues with toxins. These are kind of intermediaries that correct the innate mechanisms of combating foreign agents.
Additional effects
Tiloron affects not only the spread of viruses in tissues. This substance can suppress other pathological processes.
Properties of the drug:
- Fighting bacteria and fungi. Amiksin is not an antibiotic, but the use of this drug improves the results of treatment of bacterial diseases such as tuberculosis. Studies have also demonstrated the activity of the active ingredient against yeast and mold fungi.
- Suppression of tumor growth. Immunity protects a person from a variety of threats. This system should prevent pathological tissue growth. Modulation of the body's defense systems with tilorone reduces the risk of developing cancer.
- X-ray protection. If the drug is introduced into the body several hours before radiation exposure, the radioprotective properties of organs improve.
The complex properties of the drug find their application in various fields of medicine.
Adverse reactions
Any drug exhibits medicinal and side (adverse) properties. Drug therapy is always accompanied by certain risks, since the penetration of foreign substances into tissues can cause complications. Patients tolerate Amiksin well, but in rare cases unpleasant symptoms occur.
A doctor's consultation is required before use
Known side effects:
- Stomach ache.
- Nausea and vomiting.
- Increased gas formation in the intestines.
- Headache.
- Allergic reaction.
- Increased body temperature.
Important! Any component of the medicine can provoke an allergic reaction. Before purchasing the product, you should consult your doctor.
Tiloron is rightfully one of the least toxic antiviral agents. The risk of serious complications during therapy is minimal.
Interaction
Amiksin is well compatible with other antiviral and antibacterial agents, and can be used in conjunction with drugs for symptomatic treatment, including antipyretics, local vasoconstrictors, anti-inflammatory drugs, antihistamines, etc.
Since the active substance of the drug is metabolized in hepatocytes - liver cells, combined use with alcohol can have a negative effect on the functional state and organic structure of the liver.
With a reasonable choice of dosage of Amiksin and accompanying symptomatic medications, rapid recovery and complete restoration of body functions after viral diseases are observed.
The drug "Amiksin": analogues are cheaper. How can I replace the antiviral drug Amiksin?
In the autumn-winter period, an epidemic of viral diseases develops. Both adults and children get sick. And if one person in a family gets sick, then all its members often become infected. Among all the variety of antiviral drugs, you can often get lost. But are they all as effective as the advertisements say? And is it possible to replace the drug prescribed by the doctor with a more affordable analogue?
One of the frequently prescribed antiviral drugs is Amiksin. You can purchase cheaper analogues on your own initiative or ask your doctor to recommend a more affordable substitute.
"Amiksin": indications
The antiviral drug "Amiksin" is used for the prevention and treatment of many viral diseases, including such common ones as influenza or ARVI.
In terms of speed and harmlessness, it is significantly superior to cheaper analogues. The drug is used in the complex treatment of viral hepatitis, herpes, cytomegalovirus infection in adult patients. It can be prescribed to children over the age of seven for the treatment of viral diseases.
The antiviral drug "Amiksin" can act as a component of complex treatment of tuberculosis, multiple sclerosis, respiratory and urogenital chlamydia. The course of treatment depends on the type of disease and its degree of complexity.
Contraindications and side effects
Like many antiviral drugs, Amiksin has contraindications for use. It is not prescribed to pregnant women or children under 7 years of age. Also, the drug is not recommended during breastfeeding. You should not take Amiksin if you are sensitive to its components, as this may cause a severe allergic reaction.
There may be side effects from the use of the drug in the digestive system. During use, patients noted short-term chills and allergic reactions. The occurrence of side effects is not an indication for treatment, but in some cases appropriate treatment may be prescribed.
Composition of "Amiksin" and release forms
"Amiksin" is an antiviral drug that is available in the form of round tablets coated in an orange coating. The active substance of the drug is called tilorone. One tablet contains 60 or 125 mg of tilorone.
In addition to the active substance, Amiksin also contains auxiliary ingredients that are not medicinal in nature. For example, potato starch and microcrystalline glucose. The drug also contains primellose, calcium stearate and povidone in small doses. The tablet shell consists of titanium dioxide, hypromellose, macrogol and polysorbate.
Amiksin tablets are packaged in strips of 6 or 10 pieces, as well as in polymer jars of 6, 10 or 20 pieces. The packaging does not affect the concentration and effectiveness of the drug, and it is necessary to choose only based on the required number of tablets per course of treatment, since for long-term use it is more profitable to purchase the drug in large packages.
Methods of use and dosage of "Amiksin"
It is recommended to take the drug after meals. The dosage of the drug depends on the disease. For general cases, the recommended dose is 125 to 250 mg per day. It should be taken on the first, second and fourth days of treatment. The maximum duration of the course is one week. To prevent influenza and ARVI, one tablet is prescribed once a week for 4–6 weeks.
The course of treatment for hepatitis A is 2 weeks, during which they take 125 mg twice a day, then 125 mg per day after 48 hours. For the treatment of hepatitis B, the drug is prescribed according to the same regimen, the course of administration is 3 weeks. The course dose of the drug depends on the severity of the disease and the body’s response to treatment.
Children are prescribed Amiksin 60 mg per day during the first two days of treatment, then another 60 mg after 48 hours. For complications of influenza and ARVI, the course dose is 4 tablets, which are taken on the 1st, 2nd, 4th and 6th days of treatment.
Interaction with other drugs
Products such as Amiksin and analogues cheaper than Amiksin interact well with traditional treatment of viral infections. That is, these antiviral drugs are prescribed simultaneously with antibiotics and some other drugs used in the treatment of bacterial and viral infections. It is not recommended to combine Amiksin with other antiviral medications that have the same pharmacological effect. Such measures do not increase the effectiveness of the drug, but increase the load on the patient’s body. Before using the medication, you should inform your doctor about all medications you are taking, which will prevent the development of some side effects.
Analogues of "Amiksin"
For all its advantages, the drug has one significant drawback - high cost. For this reason, not everyone can afford Amiksin. Cheaper analogues may be less effective, but for uncomplicated infections they will do the job just as well.
There are several drugs similar in pharmacological action to Amiksin, which can be offered as a cheaper alternative. What can replace Amiksin? You can find out what analogues of the drug exist at any pharmacy. But it is better to consult a doctor who will recommend a more affordable and suitable antiviral drug.
The closest in action to Amiksin are Kagocel, Cycloferon, Ingavirin. There are many other remedies, but their effect may be much weaker.
"Kagocel"
This is an analogue of “Amiksin”, which contains kagocel as an active substance, which is an interferon inducer. In addition to the active substance, the drug also contains calcium stearate, potato starch and ludipress.
"Kagocel" has antiviral, antimicrobial and immunomodulatory therapeutic effects. It can be prescribed as an alternative replacement for Amiksin in the treatment of acute respiratory viral infections, influenza, herpes simplex and the prevention of viral infections.
Which drug is more effective - Kagocel or Amiksin? Which works better? "Kagocel" has a milder effect, so it can be used to treat viral infections in children from three years of age, unlike "Amiksin", which is recommended only from the age of seven.
"Cycloferon"
Another analogue of Amiksin is called Cycloferon. The active substances are acridoneacetic acid and N-methylglucamine. The tablets also contain methylcellulose and calcium stearate.
"Cycloferon" is prescribed as part of complex therapy for the treatment of acute forms of viral infection (ARVI, influenza), hepatitis C and B, acute intestinal infections, herpes infection and neuroinfections (serous meningitis). Can be used as an additional drug in the clinical stages of HIV infections in adults and children over the age of four years.
Tablet "Cycloferon" is an analogue of "Amiksin" in tablets, which has the same pharmacological effect. This drug can completely replace Amiksin in case of hypersensitivity to its components. Contraindications include pregnancy, breastfeeding, age under 4 years, sensitivity to substances included in the drug. Many people ask the question: “Cycloferon or Amiksin, which is better?” You should choose based on the doctor’s prescription and the complexity of the disease.
"Ingavirin"
"Ingavirin" is often prescribed by a doctor for acute forms of viral infections, including various strains of influenza, adenovirus and some other diseases. The drug can be considered as an analogue of “Amiksin” due to a similar mechanism of action, namely the activation of the production of interferon by the body’s cells.
Clinical trials of Ingavirin did not reveal any immunotoxic or allergenic effects of the drug, therefore this antiviral agent has a high level of safety. However, the drug is not recommended for pregnant and lactating women, and cannot be used in pediatrics. Side effects of Ingavirin include mild allergic reactions in patients with sensitivity to the components of the drug. "Ingavirin" can be used to prevent infection with viral infections, in particular after contact with a sick person.
It is difficult to determine which is better, “Amiksin” or “Ingavirin”. Despite the similar mechanism of action of these drugs on the virus and the patient’s body, Amiksin has a wider spectrum of action. But both remedies are effective for the prevention and treatment of simple infections, and in this case you should choose based on your financial capabilities.
Advantages of "Amiksin" over analogues
Why is the rather expensive drug “Amiksin” most often prescribed to patients? Cheaper analogues are less effective for complicated infections. The speed of action of the drug also plays an important role when choosing a good antiviral agent. Many patients cannot afford to spend several weeks in bed because of a banal ARVI and prefer to spend money once on a truly effective remedy.
The advantages of Amiksin include its low toxicity and safety when the recommended doses are observed. The drug has a long-lasting effect, and for a long time after taking it, the patient’s body will be resistant to infections caused by various viruses and bacteria.
What can replace Amiksin? Price
We reviewed analogue tablets of this drug. Now let's find out their cost. Many people know that aggressively advertised products have a higher price. Amiksin also belongs to such means. Analogues that are cheaper are most often less well-known products. But any pharmacy will suggest more affordable substitutes for an expensive drug. When purchasing cheap analogues, you must carefully read the instructions for use and compare the spectrum of action of the drugs and their indications.
The average cost of six Amiksin tablets, which are enough for a course of treatment of simple viral infections, is 600 rubles. A package of ten tablets costs around 800–900 rubles. The cost of Kagocel is significantly lower than the cost of Amiksin: only 240 rubles for ten tablets. But it is worth considering that even for the treatment of influenza or ARVI, the course dose of this drug is 18 tablets. This is three times more than the dosage of Amiksin. The cost of a course dose (20 tablets) of Cycloferon is 360 rubles, and seven capsules of Ingavirin can be purchased for 450 rubles.
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Analogues of the drug
Pharmacies offer a number of both structural analogues and drugs with similar therapeutic effects.
- One of Amiksin’s analogues is the drug Kagocel. It contains an active substance - kagocel. The effects on the human body of drugs are similar. The only thing is that Kagocel is not capable of stimulating the production of protective proteins. The advantage of the analogue is that it can treat children aged 3 years and older.
- Lavomax is also an analogue of Amiksin. They have the same active component. They also have similar dosages for both children and adults.
- The third similar drug is Ergoferon. The medication not only strengthens the defense of the immune system, but also relieves the inflammatory process. It can be prescribed to infants from 3 months of age.
- Arbidol is prescribed to children aged 2 years and older. Its disadvantage is that the drug tastes bitter. The baby may refuse to take it. A gag reflex may also occur. The medication can cure viral pneumonia. The drug is safe for young patients and is sold in pharmacies without a doctor's prescription.
- Tiloron has the same active ingredient as Amiksin. Strengthens the immune system and actively fights the virus. Produced in 60 mg tablets and 125 mg capsules.
- The drug Ingavirin has antiviral and anti-inflammatory effects. It is prescribed as an alternative to Amiksin for patients over 13 years of age for therapy. From 18 years of age for preventive purposes.
- The medicine Orvirem is prescribed to children from 1 year of age with influenza, ARVI. Produced in the form of sweet syrup. Intended for both therapeutic and preventive purposes.
Contraindications
Amiksin is a relatively safe drug, however, its use is contraindicated in the following cases:
- Pregnancy at any stage.
- The period of lactation and breastfeeding.
- Children under 7 years of age.
- Individual intolerance to the active substance and auxiliary components of the drug, development of an allergic reaction to them.
The use of the drug during pregnancy is contraindicated. If it is necessary to use the drug during lactation, breastfeeding should be discontinued.
pharmachologic effect
The drug Amiksin is an effective synthetic inducer that stimulates the synthesis of interferons belonging to the alpha, beta and gamma types. The drug is available in the form of film-coated tablets, 60 mg (Amiksin for children) and 125 mg.
The main active ingredient of Amiksin is tiporon, to the introduction of which hepatocytes (liver cells), granulocytes (one of the subgroups of white blood cells) and T-lymphocytes (lymphocytes developing in the thymus gland) and intestinal epithelial cells react, actively producing interferon.
After using Amiksin tablets (from which the maximum amount of interferon is produced within 4-24 hours), the intestines react first to tiporon, then the liver, and lastly the blood. The drug has an antiviral and immunomodulatory effect.
The use of Amiksin is effective in the treatment of many viral infections, including influenza viruses, respiratory viral infections caused by other pathogens, as well as hepatitis and herpes viruses. The antiviral effect of Amiksin is due to its ability to suppress the reproduction of viruses by inhibiting the translation of virus proteins in infected cells.
According to reviews, Amiksin is significantly superior to its analogues in terms of harmlessness, duration of action, effect obtained and breadth of use. This drug is well tolerated and non-toxic.
Amiksin is rapidly absorbed after oral administration, bioavailability (ability to be absorbed) is 60%, binding to plasma proteins is 80%. Almost unchanged, it is excreted through the kidneys (9%) and intestines (70%). Amiksin does not accumulate in the body and does not undergo biotransformation.
Side effects for the body
In the instructions for use of Amiksin you will not find information about the side effects of the medicine on the liver and kidneys (including in case of renal or hepatic failure). And this is quite fair. The thing is that Amiksin IC does not accumulate in the body and does not undergo any transformations.
Possible side effects:
- Various disorders of the digestive system;
- Various allergic reactions;
- Short-term symptoms of chills.
Analogs
Today, antiviral medications are widespread, and their choice is huge. The main analogues of Amiksin, which have a lower cost, include:
"Kagocel". The main active ingredient in this drug is carboxymethylcellulose. "Kagocel" is a cheaper drug than "Amiksin". However, it has an important drawback - the therapeutic effect from the use of this drug occurs over a fairly long period of time. A significant advantage of the drug is that it can be prescribed to children from 3 years of age. "Lavomax". Like Amiksin, Lavomax contains the active component tiloron. In terms of indications and dosage, these medications are very similar to each other. However, the cost of Lavomax is significantly lower. On average, in pharmacies the price for Lavomax is approximately 70 rubles less than for Amiksin. This difference in price is due only to the difference in packaging. The manufacturer packages Amiksin in a reliable bottle, and Lavomax is packaged in blisters. "Arbidol". It is an even cheaper drug, the effect of which is similar to Amiksin. The main active ingredient in this medication is umifenovir. The mechanism of action, despite the difference in the main substances, of Arbidol is similar to Amiksin. It is also capable of inducing the production of interferon and activating the body's immune system
However, it is necessary to take Arbidol with caution, since it belongs to group B drugs. In no case should you self-medicate; it is better to consult a specialist
"Anaferon". It is a homeopathic remedy. It is synthesized from rabbit blood serum. The main disadvantages of this drug include its weak effectiveness (if we compare this criterion with Amiksin). However, it also has advantages - it can be safely taken by pregnant women, as well as nursing mothers.
Also analogues of Amiksin are: Gepon, Sodium Nucleinate, Imudon, Septilin, Estifan, Tiloram, Tiloron, Tilaksin, Actaviron.
It is important for patients to remember that any replacement of a drug with its analogue can be made only after consultation with a doctor, who will take into account all the prerequisites for replacement and all contraindications. We continue to review instructions for use, reviews and analogues for Amiksin
We continue to review the instructions for use, reviews and analogues for Amiksin.
Contraindications and possible side effects of the drug
Despite the fact that amixin is a completely safe drug, there are some contraindications for its use:
- The child is allergic to substances contained in the drug.
- The young patient is up to 7 years old.
Before giving the drug to a child, you must make sure that there are no contraindications listed above.
Usually, taking amixin at the recommended therapeutic dose is well tolerated by the child. However, in some cases, side effects may occur:
- Nausea;
- Pain in the stomach area;
- Vomit;
- Hives;
- Itchy skin;
- Quincke's edema;
- Anaphylactic shock.
If at least one of the above symptoms appears, you must stop taking the medicine and immediately consult your pediatrician.
Manufacturers, prices, release form
The manufacturer of Amiksin is the Russian pharmaceutical company Pharmstandard LLC.
The medicine belongs to the group of antiviral immunostimulating agents. The product is available in the form of round, biconvex yellow tablets. Each dragee is in an enteric coating that protects against the aggressive action of stomach acid. As a result, the active substance (tilorone) is released and begins to act exactly where it is needed - in the small intestine.
Tablets are packaged in contour cells or jars of 6, 10 and 20 pieces. According to customer reviews, this is very convenient: different diseases require different courses of treatment. To prevent influenza and ARVI, it is enough to purchase a package of 6 tablets; for the treatment of, for example, hepatitis, it is advisable to buy a jar containing 20 tablets.
The numbers on the packages are 60 mg or 125 mg. They mean the content of the active ingredient in one tablet. For children, Amiksin is available in a dosage of 60 mg. Otherwise, the pediatric and adult forms of the medicine do not differ.
The price of the drug depends on the concentration of tilorone and the number of tablets in the package. Amiksin 60 mg costs an average of 650 rubles (10 tablets).
Composition and release form
The medicinal product contains the following substances:
Composition and instructions for use of Sebozol shampoo
- Tiloron is the main component;
- Vaseline oil, talc, magnesium carbonate, povidone, titanium dioxide, beeswax, gelatin are auxiliary components.
Release form: round tablets in a yellow coating, packaged in contour cells of 6-10 pcs. Blisters with tablets are protected by cardboard packaging, which includes instructions for use.
Important! The adult drug Amexin 125 mg is available, the instructions for use of which strictly prohibit patients under 12 years of age from taking the medicine, and Amiksin for children with a dosage of the main substance of 60 mg.
Amiksin is an antiviral and immunomodulatory agent
Amiksin is an antiviral and immunomodulatory agent. The active substance of the drug, tilorone, is a low molecular weight synthetic aromatic compound belonging to the class of fluorenones. The first information about 2,7-bis-fluorenone-9 appeared in US patent application No. 788,038 dated December 30, 1968 (RW Fleming, DL Wenstrup, ER Andrews, issued US patent No. 3592819), which describes the preparation and antiviral properties of this substance . Tilorone was synthesized in the 1970s by American chemists. The first studies discovered a fairly wide range of pharmacological activity in this compound: antitumor and antiviral, the ability to induce the formation of endogenous interferon and have an immunomodulatory effect. Such an unusual combination of properties at that time stimulated the study of the drug in many countries. In the USSR, the first information about tilorone and its interferonogenic properties appeared in an article by Z.V. Ermolyeva et al. in the journal “Antibiotics”, in 1973. This publication aroused the interest of Soviet scientists in tilorone, and in 1975. at the Physico-Chemical Institute of the Academy of Sciences of the Ukrainian SSR (Odessa) under the leadership of academician. A.V. Bogatsky and his colleagues synthesized this compound for the first time in the USSR. Research carried out soon discovered a wide range of pharmacological activity of tilorone: in addition to the ability to induce the formation of endogenous interferon and have an immunomodulatory effect, already in 1977. The antitumor and antiviral effects of the compound were revealed. The domestic drug was named “Amiksin” and since 1997 it has been approved for clinical use as an interferon-inducing, antiviral and immunomodulatory agent.
Amiksin for children
During the season of colds and infections, of course, any parent wants to protect their child from illness. It happens that a healthy regimen, walking and taking vitamins is not enough for this, and in the cold season the child gets sick at least once. Fortunately, there are means that can effectively stimulate a child’s immunity and prevent illness or, if it was not possible to protect oneself, speed up recovery. One of these drugs is the drug amiksin.
Amiksin (amiksin ic) is an antiviral immunostimulating agent, an inducer of alpha, beta and gamma interferon. An increase in the level of interferons is observed 4 hours after the first dose of the drug, and the maximum production of interferons is observed in the first 24 hours of treatment. The active ingredient – tilorone (tilaxin) – is a synthetic low-molecular compound that stimulates humoral immunity and has anti-inflammatory properties.
As possible side effects, the instructions for amiksin indicate allergies, chills, and dyspeptic symptoms.
Amiksin - indications for use
Amiksin is used in adults for the prevention and treatment of influenza, other acute respiratory viral infections, and the treatment of viral hepatitis A, B and C. Amiksin is effective in the treatment of herpetic and cytomegalovirus infections, encephalomyelitis of an infectious-allergic and viral nature, chlamydia, and pulmonary tuberculosis.
Amiksin or amiksin ic for children over 7 years of age can be prescribed for the treatment of influenza and other acute respiratory viral infections.
Often, in the case of the treatment of viral diseases, immunomodulatory drugs are effective only when taken in the first hours of the disease, and if treatment is delayed, they are useless. Unlike many other interferon inducers and immunostimulating drugs, amiksin has no restrictions on the timing of prescription, that is, it can be used both from the first hours of the disease (which, of course, enhances its effectiveness) and for delayed treatment.
Amiksin is compatible with antibiotics, other antiviral agents and drugs for the symptomatic treatment of infectious diseases.
How to take amiksin?
Amiksin is available in the form of tablets 60 mg (for children) and 125 mg (for adults). Amiksin is taken orally after meals. The dosage of amixin is selected depending on the age and purpose of use of the drug (prevention or treatment, type of disease).
Amiksin is gaining popularity as a preventive drug for adults due to its ease of use: to prevent influenza and other acute respiratory viral infections, you need to take only 1 tablet (125 g) per week for 6 weeks.
The regimen for taking amixin for the treatment of hepatitis and other serious infectious diseases is best agreed with your doctor. Here we will only describe how to take amiksin for colds, flu and other acute respiratory viral infections. Adults with the onset of the disease need to take one tablet (125 g) in the first two days. Then one tablet every other day (on the 4th, 6th, 8th and 10th days of treatment).
According to the instructions for use of amixin, children over 7 years of age with uncomplicated influenza or other acute respiratory viral infections are prescribed 60 mg per day on the 1st, 2nd and 4th days of the disease (a total of 3 tablets are taken per course of treatment). To treat complications of influenza or ARVI, you need to take 4 tablets: on the 1st, 2nd, 4th and 6th days from the start of treatment.
Amixin is also prescribed to children for the prevention of influenza and ARVI. The prophylactic course for a child is 60 mg once a week.
within 6 weeks.
How often can you take Amixin?
Unfortunately, as a rule, the epidemic season exceeds 6 weeks in duration (the duration of the prophylactic course of amixin). Therefore, those who want to avoid getting sick during this difficult time have a logical question: how often can you take Amixin?
Unfortunately, there is no information anywhere about how much time should pass between courses of taking amixin. But for prevention, experts consider it acceptable to use amiksin 1 to 3 times a year.
Analogs of amixin are the drugs Lavomax and Tiloron.
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Recommendations for use
The medicine is taken orally, after meals, with a sufficient amount of water. The dosage depends on the severity and etiology of the disease:
- Prevention of nonspecific viral hepatitis A - 125 mg once a week for a course of 6 weeks. During treatment, a course dose: 125 mg for 1 day, then the same dose every other day in a course of 10 tablets.
- Acute hepatitis B initial form: first and second day, the dose of the drug is 125 mg/day, then 125 mg after 48 hours, the total course is 2 g (16 tablets). In case of chronic pathology, the course dose is 20 tablets, the scheme is the same.
- Acute hepatitis C on the first and second days 125 mg/1 time per day, then 125 mg every 48 hours, course of 20 tablets. Chronic form: 250 mg/1 time per day for the first 2 days, after 125 mg every other day in a course of 20 tablets. The further duration of treatment is determined by a specialist. As a rule, Amiksin is taken for up to six months with a total course of 40 tablets.
- As part of complex therapy for neuroviral infections: 125-250 mg/day for the first two days, then 125 mg every 2 days, duration of administration up to 4 weeks.
- ARVI, influenza - the first two days 125 mg/14 times every 7 days for a course of up to 6 weeks, total dose 6 tablets (750 mg.). The drug is taken in the same way to prevent diseases.
- Herpathic, cytomegalovirus infection: in the first two days, 125 mg/1 time per day, then 125 mg every 48 hours in a course of 10-20 tablets (depending on the severity of the pathology).
- Urogenital, respiratory chlamydia: 125 mg/day for the first 2 days, then 125 mg every 48 hours.
- Complex therapy of tuberculosis lung pathology: the first 2 days, 250 mg/1 time per day, then 125 mg every 48 hours in a course of 20 tablets.
- For genital herpes of the primary type, the dosage is 250 mg/1 time per day for the first 2 days, then 125 g/day every 48 hours for up to 4 weeks. The same regimen is used for exacerbations and relapses of pathology. The course of the drug for prevention is 125 mg once a day, then a break of 60 days, during which the patient receives symptomatic treatment in the form of a herpetic polyvalent vaccine, 1/5 ml every 3-4 days, then after 10 days. The last stage involves taking Amiksin once a week for a course of 8 weeks.
Standard form of treatment:
- For uncomplicated forms of influenza, ARVI - 60 mg/day for a course of 3 days.
- If complications develop, 60 mg/day for a course of 4 days.
Any dosage changes are recommended by the attending physician.
Reception features
Amiksin is prescribed to children over 7 years of age. How to take medicine to treat various viral diseases is described in detail in the instructions. In any case, self-medication is unacceptable - the possibility of using the drug and its dosage regimen is determined by the doctor.
The doctor will prescribe a treatment regimen!
Let's consider the most common cases of using Amiksin in pediatrics - prevention and treatment of influenza and ARVI.
In order to prevent epidemics of colds during the season, Amiksin (at a dosage of 60 mg) is enough to take one tablet per week. The duration of the course is 6 weeks.
To treat ARVI and influenza, give Amiksin to your child one tablet on days 1, 2 and 4.
If the disease occurs with complications, the course is extended: tablets are taken on days 1, 2, 4 and 6. Attention: in this case, a regular consultation with a pediatrician is required, who, after assessing the patient’s condition, may prescribe additional medications.
The tablets should be taken after meals with plenty of liquid, without chewing or crushing. The medicine combines well with traditional drugs used to treat influenza and acute respiratory infections, including antibiotics.
You need to eat before taking the pill.
There is no official answer to the question of how often you can take Amiksin. According to doctors, the optimal number of courses per year (for preventive purposes) is from 1 to 3.
What's better
Comparative analysis of Amiksin with its analogues.
Amiksin or Lavomax
Medicines with the same functions and active ingredients have similar indications and side effects. Even their prices are not much different. But Lavomax is inferior in dosage, since it is available in only 0.125 g, and it is allowed to be taken only upon reaching 18 years of age. Additional components of medicines also differ. Lavomax contains sucrose and beeswax, which excludes its use for some patients, for example, patients with diabetes.
Amiksin or Ingavirin
Both drugs are used to treat colds and flu, but their composition and effect differ. The main feature of antiviral drugs is their additional properties: Ingavirin has anti-inflammatory properties, Amiksin has immunomodulatory properties. The range of diseases for which Amkisin is used is wider.
Cycloferon or Amiksin
Drugs with a general immunomodulatory antiviral effect have different active ingredients and auxiliary components
The indications for the medications are identical, but the list of side effects and contraindications for Cycloferon is longer. When choosing a medication, you should pay attention to the age and individual characteristics of the body.
Arbidol or Amiksin
These are not structural analogues; their active components are different. Amiksin, unlike Arbidol, has a larger list of indications. The advantages of Arbidol tablets, capsules and syrup are the variety of release forms and age restrictions - the drug is approved from 3 years.
Ergoferon or Amiksin
The mechanism of action of the drugs is different, as is their proven effectiveness: Amiksin has passed clinical testing, Ergoferon has not.
Kagocel or Amiksin
Medicines of the same pharmacological group and with a similar mechanism of action have different effects. Interferon penetrates into the blood after taking Kagocel after 48 hours, Amiksin - after 24 hours. In the case of treating children, Kagocel can be given to children from 3 years of age. Amiksin is more relevant for the prevention of ARVI and influenza.
Amiksin's analogs
Level 4 ATX code matches:
Estifan
Septilin
Sodium nucleinate
Gepon
Imudon
Lavomax
Immunokind
Immunal
Ruzam
Glutoxim
Histamine dihydrochloride
Pyrogenal
Timalin
Cycloferon
Uro-Vaxom
Engystol
Imunofan
Imunorix
Kipferon
Tsitovir-3
Analogs of Amiksin are the drugs Actaviron , Lavomax , Tilaxin , Tiloron , Tiloram . The optimal drug should be chosen by the treating specialist.
Directions for use and dosage of Amiksin
Amiksin tablets should be taken orally after meals.
The dosage for children is 60 mg once a day on the first, second and fourth days of treatment. The total course dose is 3 tablets of 60 mg. If complications develop, the drug is taken in the same dose, in the same way, plus an additional tablet on the sixth day of treatment, i.e. a total of 240 mg (4 tablets).
The dose of Amiksin for adults depends on the type of disease and indications.
To prevent influenza and acute respiratory viral infections, the drug is prescribed in 1 tablet. once a week for 6 weeks. The total dose is 6 tablets. (750 mg).
For the treatment of ARVI and influenza, Amiksin is taken according to the following regimen: on the first and second days, 125 mg once, then 125 mg every other day. The total number of tablets is 6 pcs.
For nonspecific prevention of viral hepatitis A, take one 125 mg tablet once a day for 6 weeks. Course dosage – 6 tablets.
For the treatment of viral hepatitis A, on the first day take 125 mg twice a day, then 1 tablet. – every 48 hours. Course dose – 10 tablets. Amiksin (1.25 g).
For acute hepatitis B, take 1 tablet in the first two days, then every other day. The general course is 6 tablets (2 g), for a prolonged course of the disease - 20 tablets. (2.5 g). Acute hepatitis C is treated similarly to long-term hepatitis B.
When treating chronic hepatitis C, 250 mg per day is prescribed on the first and second days, then 125 mg every other day. In total, the patient must take 20 tablets in this phase of treatment. After this, he is transferred to taking the drug one 125 mg tablet once every seven days for 20 weeks. Thus, in total, the patient should take 20 Amiksin 125 mg tablets over 6 months. During this period, morphological, immunological and biochemical studies are regularly carried out, which reflect the degree of activity of the process; based on their results, the doctor can adjust the treatment regimen.
For chronic hepatitis B, take 250 mg in the first two days, then 125 mg every other day. In the continuation phase of treatment, the dose of Amiksin is 125 mg once a week, the total dose is from 10 (1.25 g) to 20 (2.5 g) tablets. The total duration of treatment is from 3.5 to 6 months, depending on the results of immunological, biochemical and morphological studies, reflecting the degree of activity of the process.
As part of the complex treatment of pulmonary tuberculosis, Amiksin is prescribed according to the following regimen: on the first and second days, 250 mg per day, then 125 mg at intervals of 48 hours. Course dose – 20 tablets (2.5 g).
In all other cases, the drug is taken at 125 mg in the first two days, then 1 tablet every 48 hours, only the duration of treatment and the total number of tablets differ:
- For complex therapy of neuroviral infections - 10-15 tablets;
- For herpetic and cytomegalovirus infections - 10-20 pcs.;
- For urogenital and respiratory chlamydia – 10 pcs.
Indications
Like any other medicine, Amiksin must be prescribed by a doctor who takes full responsibility for all changes in the body that this drug can cause: both positive and negative.
Indications for use for adults:
- for the prevention and treatment of influenza and ARVI;
- for the treatment of viral hepatitis A, B and C;
- for the treatment of herpes infection and cytomegalovirus infection;
- as part of complex therapy of allergic and viral encephalomyelitis (including multiple sclerosis, leukoencephalitis, uveoencephalitis);
- as part of complex therapy of urogenital and respiratory chlamydia;
- as part of complex therapy of pulmonary tuberculosis.
Indications for the use of Amiksin for children over 7 years of age are determined - the treatment of colds and flu.
Instructions for use of Amiksin for adults
The tablets should be taken immediately after the main meal. You should drink it with clean water, preferably mineral water.
When using Amiksin by adult patients, it is recommended to take it in the following dosages:
- In order to combat acute respiratory disease, for the purpose of therapeutic effects on parainfluenza and influenza, it is necessary to take 125 mg of the drug once a day in the first two days. Next, the dosage regimen must be changed and Amiksin taken 125 mg once every 48 hours. During the entire course of treatment, it is expected to take no more than 6 tablets of the drug, for a total of 750 mg.
- When preventing viral infections, you should take a single dose of 125 mg of the drug every 14 days. The entire course of prophylactic administration lasts six weeks and involves taking 750 mg of Amiksin, that is, 6 tablets.
- In order to have a therapeutic effect on infectious diseases provoked by the simple herpes virus, the medication should be taken according to a specific regimen. In the first two days, a single dose of 125 mg per day is indicated, and then 125 mg once every two days. The duration of therapy in this case is 14 days. During the entire period of therapy, no more than 20 tablets are allowed.
- In order to have a therapeutic effect on infectious diseases provoked by cytomegalovirus, the drug must be taken according to the same regimen as for the treatment of herpetic infections.
- To prevent hepatitis A, you should take 125 mg of the drug once every 14 days. The total duration of the course is 6 weeks.
- For the treatment of hepatitis A in the acute period, you should take 125 mg once a day for the first two days, and then 125 mg once every two days.
- For the purpose of treating hepatitis B, which is in the acute period, Amiksin should be taken according to the same regimen as for the treatment of hepatitis A. During the entire course of treatment, it is permissible to take no more than 16 tablets of the medication. If the viral disease is severe, you should take 125 mg twice a day for the first two days. Next, you need to adhere to the dosage regimen: 125 mg once every two days. During the entire treatment period, you should take no more than 20 tablets.
- Therapy for hepatitis B, which has a chronic course, is carried out in 2 phases. At the initial phase of treatment, the patient should take 250 mg once in the first two days, and then 125 mg once every two days. In the continuation phase, a single dose of one Amiksin tablet every 7 days is recommended. The course of treatment for chronic hepatitis B can last up to six months. For the entire course, you can take no more than 5 grams of Amiksin. The effectiveness of treatment with an antiviral drug is determined based on diagnostic data - symptomatic picture, laboratory parameters, results of biochemical studies, immunological tests.
- Treatment of chronic and acute hepatitis C involves taking the drug according to a regimen similar to the treatment regimen for hepatitis B.
- Complex therapy for neuroviral infection involves taking 250 mg of the drug once every two days, and then 125 mg once every two days.
- For the purpose of therapy as part of the combined treatment of tuberculosis, 125 mg should be taken twice a day (during the first two days), and then 125 mg should be taken once every two days.
- For the treatment of urogenital chlamydia, it is recommended to take 1 tablet. once for the first two days, and then once, 1 tablet. in Week. The entire course of treatment involves taking no more than 10 tablets.
Therapy for children from 7 years of age involves taking Amiksin according to the following regimens:
- Treatment of colds and acute respiratory viral infections involves a single dose of 60 mg of the drug. For the entire course, you should take 180 mg of the drug - 60 mg on the first, second and fourth days.
- If influenza or acute respiratory infections have a complicated course, then Amiksin is prescribed in a dosage of 60 mg, which should be taken on the first, second, and then on the fourth and sixth days. The total amount of the drug for the entire course of therapy is 240 mg, that is, 4 tablets.
Indications for use
Taking into account numerous studies of the clinical use of immunomodulators, we can say that the main indication for the prescription of medications in this group is disruption of the immune system.
In adults and children over 7 years of age, it is used for the prevention and treatment of various acute viral respiratory (respiratory) infections and influenza.
Indications for use in adults are the treatment of diseases such as:
- Hepatitis, viral etiology (A, B, C),
- Herpes infection types 1 and 2,
- Cytomegaly virus infection
- Chlamydia affecting the genitourinary organs and/or respiratory system,
- Pulmonary tuberculosis (as part of complex therapy),
- Multiple sclerosis,
- Damage to the spinal cord and brain of an allergic and/or viral nature (including leukoencephalitis, uveoencephalitis).
In addition, immunomodulators are prescribed for complicated acute viral infections (sinusitis, bronchitis, pneumonia), massive surgical interventions, radiation and chemotherapy in cancer patients.
Children's "Amiksin"
The drug "Amiksin" can be used for the treatment of children from 7 years of age. The drug has an immunostimulating effect, due to which it can be used not only for therapy, but also for preventive purposes. Before starting to use Amiksin, it is imperative to consult a specialist. You should not start self-treatment of your child with this drug.
Instructions for use for Amiksin 60 mg are similar to those for the adult dosage.
The main difference between a children's drug and an adult is its dosage. It contains less active substance - 60 mg versus 125 mg.
Quite often it is prescribed to children for the treatment of ARVI and influenza. In this case, you should take the antiviral medication for at least a week.
The instructions for use for children's "Amiksin" confirm this.
What diseases does Amixin help prevent?
Amiksin is taken to prevent all acute respiratory viral infections. These include several diseases; the table shows some of them. It is important to recognize the first symptoms of ARVI in order to choose the right tactics, and the type of virus will play a secondary role.
ARVIs are transmitted mainly by airborne droplets (less often by contact). Basic rules of hygiene are partly the prevention of acute respiratory viral infections and other diseases in principle - cover your nose or mouth with something when coughing or sneezing, wash your hands, take enough vitamins (during periods of epidemic, vitamin C is especially important, which has a beneficial effect on the immune system).
And the eternal thing - quit smoking. Infectious agents, entering the respiratory tract, settle precisely on the mucous membranes of this area. Smoking itself irritates the respiratory tract and reduces immunity at both the local level and at the level of the whole organism.
Symptoms | Prevention scheme | |
Flu | A sharp rise in temperature to 39 °C -40 °C, headache (mainly in the forehead), after 1-2 days nasal congestion, “scratching” in the throat, cough with phlegm, sweating. The pulse quickens. | Amiksin, 125 mg – once a week for 6 weeks. |
Parainfluenza | Gradual development of the disease. Hoarseness of voice, a rough barking cough appears, then nasal congestion and runny nose develop. The temperature rises slightly. The main symptom remains a persistent cough. | |
Rhinovirus infection | It is also called “contagious runny nose.” It manifests itself as nasal congestion and dryness, copious, gradually thickening nasal discharge. Possible headache, hoarseness. The most striking sign of rhinovirus infection is the almost complete absence of symptoms of intoxication in combination with severe rhinorrhea and possible pharyngitis. | |
Adenovirus infection | In adults, the temperature is not prone to strong rises, nasal congestion, runny nose, pain and sore throat, inflammation of the tonsils, enlarged lymph nodes, conjunctivitis. | |
MS infection | More common in children. Mild chills, temperature up to 37°C -38°C. On day 2-3, nasal discharge begins. An important symptom is a dry persistent long cough and difficulty breathing. |
Contraindications for use
According to the instructions for use, Amiksin should not be used by women during pregnancy, as well as by children under 7 years of age. In addition, Amiksin should not be taken by patients who have a history of allergic reactions to any of the components contained in the drug.
The use of Amiksin by pregnant women is strictly prohibited. Amiksin can be prescribed to breastfeeding women if there is an urgent need for it. However, lactation must be suspended while taking the pills.
Next, let's look at the instructions for use of Amiksin for children.
Advantages of "Amiksin" in comparison with analogues
Antiviral medication is more expensive, but at the same time more effective. When taken, the therapeutic effect occurs faster, and the achieved result lasts much longer. Amiksin can be taken both for therapy and for the prevention of certain viral diseases. It is advisable to give preference to Amiksin if the acute respiratory infection has a complicated course.
Along with the fight against viruses, Amiksin has an immunomodulatory effect on the patient’s body. The medication is characterized by low toxicity, which ensures safety if the recommended dosage is followed.
Very often, doctors recommend Amiksin as an effective means of preventing influenza and parainfluenza.
Instructions for use for Amiksin tablets should be read in advance.
Amiksin: instructions, indications, contraindications, analogues
The instructions for Amiksin say that the drug can significantly alleviate the symptoms of many diseases, and sometimes effectively prevent their development. No one is immune from the effects of viruses - pathogenic agents are in the environment and every person is constantly in contact with them.
The content of the article:
If the immune system works without failures, providing complete protection to the body, you don’t have to worry about the occurrence of the disease. But if immunity is lowered, viral agents easily penetrate the mucous membrane of the respiratory tract and begin to actively multiply, causing symptoms of ARVI.
Amiksin IC has two goals:
- Children's Amiksin helps the body fight infectious agents while reducing natural protective factors.
- Amiksin and its generics are designed to effectively combat viruses that have already penetrated, blocking their activity and preventing harmful effects on the body.
Amiksin for children is an effective antiviral agent, the active component of which is tilorone. This substance, when taken orally, stimulates the release of special protective proteins - interferons.
Their main function is the elimination of pathogenic agents that have entered the body.
There are three types of interferons, each of which affects certain viruses and helps the body get rid of harmful microorganisms in a timely manner. The antiviral drug Amiksin specifically activates their production, boosting the immune system if necessary.
Instructions for use
EXPAND AMIXIN INSTRUCTIONS
Amiksin
Composition and release form
The tablets are coated from light yellow to yellow, round, biconvex; on a cross section, 2 layers are visible; the core of the tablet is orange.
1 tablet contains tilorone 60 or 125 mg excipients: basic magnesium carbonate, PVP, calcium stearate, aerosil, vaseline oil, sugar, talc, tropeolin O, titanium dioxide, gelatin, beeswax in polymer jars of 6 or 10 pcs. pack of cardboard 1 can.
pharmachologic effect
Amiksin is an antiviral drug, an inducer of interferon synthesis.
Effective against many viral infections (including those caused by influenza viruses, other pathogens of acute respiratory viral infections, hepatitis viruses, herpes).
The mechanism of antiviral action is associated with inhibition of the translation of virus-specific proteins in infected cells, as a result of which viral reproduction is suppressed.
Amiksin stimulates the formation of interferons alpha, beta, and gamma in the body. The main structures that produce interferon in response to the administration of Amiksin are intestinal epithelial cells, hepatocytes, T-lymphocytes, and neutrophils. After taking the drug orally, the maximum interferon production is determined in the intestine-liver-blood sequence after 4-24 hours.
Amiksin has an immunomodulatory effect: it stimulates bone marrow stem cells, depending on the dose, enhances antibody formation, reduces the degree of immunosuppression, and restores the T-helper/T-suppressor ratio.
Amiksin, indications for use
- viral hepatitis A, B and C
- herpetic infection
- cytomegalovirus infection
- influenza and ARVI (prevention and treatment)
- as part of complex therapy of infectious-allergic and viral encephalomyelitis (multiple sclerosis, leukoencephalitis, uveoencephalitis)
- as part of complex therapy of pulmonary tuberculosis
- as part of complex therapy of urogenital and respiratory chlamydia.
For children over 7 years old:
Contraindications
- pregnancy
- lactation (breastfeeding)
- age up to 7 years
- hypersensitivity to the drug.
Directions for use and doses
For nonspecific prevention of viral hepatitis A, the drug is prescribed at a dose of 125 mg per week for 6 weeks.
When treating viral hepatitis A, the dose of the drug on the first day is 125 mg 2 times a day, then switch to taking 125 mg every other day. The course of treatment is 1.25 g (10 tablets).
When treating acute hepatitis B, on the first and second days the dose of the drug is 125 mg/day, and then 125 mg every other day. The course of treatment is 2 g (16 tablets).
In case of protracted hepatitis B, on the first day the dose of the drug is 125 mg 2 times a day, then 125 mg every other day. The course dose is 2.5 g (20 tablets).
For chronic hepatitis B in the initial phase of treatment, the total dose is 2.5 g (20 tablets). In the first 2 days, the daily dose is 250 mg, then switch to taking 125 mg every other day. In the continuation phase of treatment, the total dose ranges from 1.25 g (10 tablets) to 2.5 g (20 tablets), while the drug is prescribed at a dose of 125 mg per week.
The course dose of Amiksin varies from 3.75 to 5 g, the duration of treatment is 3.5-6 months. depending on the results of biochemical, immunological and morphological studies, reflecting the degree of activity of the process.
For acute hepatitis C, on the first and second days of treatment, Amiksin is prescribed at a dose of 125 mg/day, then 125 mg every other day.
The course dose is 2.5 g (20 tablets).
For chronic hepatitis C in the initial phase of treatment, the total dose is 2.5 g (20 tablets). In the first 2 days, the drug is taken at a dose of 250 mg/day, then 125 mg every other day.
In the continuation phase of treatment, the total dose is 2.5 g (20 tablets), while the drug is prescribed at a dose of 125 mg per week. The course dose of Amiksin is 5 g (40 tablets), the duration of treatment is 6 months. depending on the results of biochemical, immunological and morphological studies, reflecting the degree of activity of the process.
To prevent influenza and ARVI, Amiksin is prescribed at a dose of 125 mg once a week for 6 weeks.
For the treatment of influenza and other acute respiratory viral infections in the first 2 days of illness, Amiksin is prescribed at a dose of 125 mg/day, then 125 mg every other day. The course dose is 0.75 g (6 tablets).
For the treatment of herpetic and cytomegalovirus infections, the dose of the drug in the first 2 days is 125 mg, then 125 mg is taken every other day. The course dose is 2.5 g (20 tablets).
For urogenital and respiratory chlamydia, Amiksin is prescribed at a dose of 125 mg/day for the first 2 days, then 125 mg every other day. The course dose is 1.25 g (10 tablets).
In complex therapy of neuroviral infections, the dose is set individually, the course duration is 4 weeks. In complex therapy of pulmonary tuberculosis, in the first 2 days the drug is prescribed at 250 mg/day, then 125 mg every other day. The course dose is 2.5 g (20 tablets).
Children over 7 years of age are recommended to use the drug in the form of 60 mg tablets.
For uncomplicated forms of influenza or other acute respiratory viral infections, the drug is prescribed at a dose of 60 mg (1 tablet) per day after meals on the 1st, 2nd and 4th day from the start of treatment. The course dose is 0.18 g (3 tablets).
If complications develop, the drug is taken on the 1st, 2nd, 4th, 6th day from the start of treatment. The course dose is 0.24 g (4 tablets).
The drug is taken orally after meals.
Side effect
From the digestive system: in some cases - symptoms of dyspepsia. Other: short-term chills and allergic reactions are possible.
special instructions
As part of complex therapy for neuroviral infections, Amiksin is used under medical supervision.
Amiksin is compatible with antibiotics and traditional treatments for viral and bacterial infections.
Storage conditions
The drug should be stored in a dry place, protected from light.
Shelf life: 3 years.
Indications for use
Amiksin has found wide use in the treatment of viral hepatitis and herpes lesions. The instructions for the drug Amiksin say that the drug is prescribed for cytomegalovirus infection.
The main indication for the use of Amiksin is any acute viral respiratory disease. The instructions say that Amiksin IC differs from similar immunostimulating drugs in that it acts specifically on all three types of interferons - alpha, beta and gamma.
That is why its effect applies to most viral agents, regardless of the affected organ.
Thyrolone, which is part of the drug Amiksin, is often included in the complex therapy of encephalitis and encephalomyelitis caused by viruses.
The instructions for Amiksin IC indicate that the drug can also be prescribed for severe general non-viral diseases, for example, tuberculosis. An indication for the use of Amiksin is intracellular infection - chlamydia.
The drug Amiksin stimulates the immune system and increases the body's resistance. Pediatricians believe that the best effect can be obtained from Amiksin for influenza.
Weak and often sick children should take Amiksin as the main medicine for ARVI.
Amiksin for children
The manufacturer of Amiksin indicates that the drug is most effective in the treatment of viral infections of the respiratory system when the body’s own immunity is reduced. In this case, Amiksin IC can be prescribed as the main drug or as an addition to other cold medications.
The latter treatment option is justified in severe cases of the disease, when there is a need for additional treatment with antibiotics or there is a high probability of complications.
How should children take Amiksin to prevent ARVI? The annotation for Amiksin states that the children's dosage is 60 mg of tyrolone. Judging by the reviews of doctors, Amiksin for children is an excellent preventive measure.
To avoid a viral infection, it is enough to give just one tablet of Amiksin for children every week. The break between doses should be 7 days; the course of Amiksin Aisi is designed for 6 weeks.
How to take Amiksin for children with a cold? Reviews from doctors say that Amiksin for children from the age of seven with colds should be taken according to the following scheme: 60 mg of the drug is prescribed once on the first, second and fourth days of the disease. That is, when treating a simple flu, it is enough to take only three tablets.
The manufacturer of Amiksin indicates that if there are complications of a viral infection, a 4th tablet should be added on the sixth day of treatment.
You can repeat treatment with Amiksin for children no more than three times a year. If this treatment regimen is violated, the effectiveness of Amiksin for children may significantly decrease.
Reviews show that you should strictly adhere to the treatment schedule.
Amiksin - how to take
The annotation for Amiksin states that the drug is protected by a special coating that prevents the destruction of the active component in the acidic environment of the stomach. Thyrolone is activated in the intestinal lumen, absorbed into the bloodstream.
Therefore, Amiksin tablets should be swallowed whole, without chewing or crushing before use. Antiviral Amiksin is taken after meals.
Amiksin - an antibiotic or not?
With good immunity, the body itself is able to cope with the virus. However, when it decreases, Amiksin tablets can provide significant support to the body. As statistics show, many patients find it difficult to say for sure whether Amiksin is an antibiotic or not.
Many are misled by the name of this drug, which is similar to the well-known antibacterial agents - Amoxicillin or Ampicillin. The active ingredient of Amiksin, tyrolone, is part of the group of antiviral drugs.
Therefore, we can say with confidence that Amiksin is not an antibiotic.
Unlike antibacterial drugs, the prescription of the antiviral drug Amiksin is almost always justified. The composition of Amiksin helps not only to cope with the pathogenic agent, but also to mobilize the body’s own defenses.
It should be recalled that antibiotics act exclusively on bacteria and have no effect on viruses. The composition of the drug Amiksin specifically fights against viral agents.
Indirectly, the medicine can have a positive effect on bacterial infections, increasing the body's resistance. Therefore, in case of severe bacterial lesions, Amiksin or its generics should be included in antibacterial and anti-inflammatory therapy - this will increase the effectiveness of treatment and speed up recovery.
Contraindications to Amiksin
The following conditions are contraindications to taking Amiksin:
- Carrying a child is considered a contraindication to Amiksin. During pregnancy, Amiksin should not be taken at any time.
- The instructions for Amiksin indicate that the medicine should not be taken while breastfeeding.
- Amiksin and its cheap analogues should not be prescribed to children under seven years of age.
- Compatibility of Amiksin and alcohol is conditional. You should not drink alcohol during treatment with Amiksin, although it is not contraindicated. However, it should be taken into account that the simultaneous prescription of antibiotics with Amiksin puts a taboo on drinking alcohol - after all, alcohol and antibiotics are incompatible.
- Amiksin and its cheap analogues should not be prescribed if an allergic reaction to tyrolone or components of the drug has previously been noted.
Which is better - Kagocel or Amiksin
Many people are interested in the question: “Which is better - Kagocel or Amiksin?” These are completely interchangeable drugs belonging to the group of antiviral drugs. The active ingredients are different, but the pharmacological effects of Kagocel and Amiksin are similar.
Both drugs stimulate the body’s production of its own interferons, so it’s difficult to say unequivocally which is better.
Amiksin contains tyrolone, which can induce cells of the immune system to produce interferon gamma; Kagocel is deprived of this function. You can take Amiksin for both ARVI and colds. Considering the fact that Kagocel costs almost half as much, if necessary, you can replace one drug with another.
The undoubted advantage of Kagocel is that it can be prescribed to children from the age of three, while Amiksin is allowed only from the age of seven.
Ingavirin or Amiksin - which is better?
Let's figure out which is better - Ingavirin or Amiksin? Amiksin's spectrum of activity is undoubtedly wider, so this drug is better than Ingavirin in helping with acute viral diseases.
Ingavirin is often recommended for prophylactic purposes during the flu season.
Amiksin or Lavomax - which is better?
What helps better - Amiksin or Lavomax? Considering that the active antiviral component of these drugs is thyrolon, the question “Amiksin or Lavomax - which is better?” not entirely correct. The dosage of these medications for children and adults is the same, the indications and contraindications are similar.
Therefore, it would be legitimate to say that Lavomax is a structural analogue of Amiksin, completely replacing it.
According to reviews, Amiksin copes well with the symptoms of ARVI. In severe conditions, the inclusion of medication in complex therapy can significantly alleviate the course of the disease.
In the reviews you can see that Amiksin is well tolerated, rarely causing side effects. Cases of allergic reactions have been described; the functioning of the digestive system may be disrupted.
Taking Amiksin itself can cause a flu-like reaction, accompanied by chills, headache and nasal congestion - these side effects are harmless and go away on their own after stopping treatment.
Amiksin has a number of analogues that differ in their spectrum of action and activity. Antiviral drugs that are analogues of Amiksin: Kagocel, Ingavirin, Lavomax, Arbidol, Cycloferon, Oscilococcinum, Anaferon.
Terms of sale and storage
In pharmacies, Amiksin with a dosage of 125 mg is sold freely, without a prescription from a doctor. But the medicine, which has a dosage of 60 mg, can be purchased only with a prescription from a pediatrician.
According to the instructions for use for adults, “Amiksin” 125 mg, it should be stored in a place protected from moisture and direct sunlight, at an optimal temperature of up to 30 degrees Celsius. If storage conditions are met, then Amiksin retains its therapeutic properties for three years from the date of its manufacture. It is not recommended to use the drug after its shelf life has expired.
Such information is contained in the instructions for use of Amiksin for adults in tablets.
Reviews
First of all, all doctors warn patients against uncontrolled use of Amiksin; it should be taken only as directed, if there are indications. Most of the patient reviews about this drug are positive. However, there are also neutral ones. The first report that the drug helps to quickly relieve the unpleasant symptoms of viral respiratory diseases and strengthen the immune system. Others say that the drug, in their opinion, is useless. Both categories of patients note that adverse reactions during the use of Amiksin develop extremely rarely.
We reviewed the instructions for use and reviews for the drug “Amiksin”.
Amiksin compatibility
Compatibility of the drug with alcohol. Alcohol passes through the liver, as do medications. When taking an antiviral drug and alcohol in parallel, one of the two substances will enter the body without having time to be processed, since the liver cannot cope with such a load. As a result, a number of side effects can occur: intoxication, allergic reactions and dysfunction of the digestive system.
Compatible with antibiotics. The immunomodulator and antiviral agent can be taken in combination with other medications and antibiotics.
Action of Amiksin in the prevention of influenza and ARVI
Amiksin is a combined medication that stimulates the formation of different types of endogenous interferons in the body. Interferons are special proteins that actively fight pathogenic organisms.
Amiksin for influenza strengthens the body's defenses. The immune system suppresses the negative effects of viruses and also prevents the occurrence of allergic reactions. In a very short period of time, the medication eliminates any manifestations of a cold, blocks the pathogenic activity of viruses and eliminates acute inflammatory processes.
The main active component is tilorone. It promotes the formation and activation of interferon inducer cells in the liver and intestines. They help break down and remove dead viruses and bacteria from the body.
The drug also activates macrophage cells. It not only increases their absorption capacity, but also the production of reactive oxygen species. They are characterized by a bactericidal effect. Cells begin to form in the lymph that fight back all viruses and adapt the body to them.
Numerous reviews of Amiksin indicate that this antiviral drug is well tolerated in the vast majority of cases and does not have side effects if the dosage recommended by the doctor is followed.
Rarely do patients complain of short-term chills. Dyspeptic symptoms occur even less frequently. In individual cases, allergic reactions are possible due to hypersensitivity or intolerance to one or another component of the medication.
Cases of overdose of Amiksin have not been reported in medical practice; however, it is not recommended to exceed the dose prescribed by the doctor, since short-term depletion of immunocompetent cells is possible.
Once in the human body, tilorone is quickly absorbed in the gastrointestinal tract, after which it is transferred with plasma proteins to various tissues. This compound stimulates the intestinal epithelium, T-lymphocytes, granulocytes, as well as hepatocytes, as a result of which the active production of alpha, gamma and beta interferons begins in such cells.
First, interferon begins to be produced in the intestines, then in the liver and in the blood. The maximum effect on the synthesis of interferons is observed 2-24 hours after taking Amiksin.
The medicine affects the bone marrow, activating stem cells in it. Tilorone also has an effect on the production of immunoglobulins types A, G and M. The drug has a beneficial effect on humoral immunity and stimulates the appearance of antibodies. In addition, treatment with Amiksin helps restore the normal proportion of T-suppressor and T-helper cells, as a result of which immunosuppression is reduced.
The antiviral effect of tilorone is due to the inhibition of protein production in virus-infected cells, which is why the reproduction of the pathogen is inhibited. The drug acts on ARVI viruses, hepatoviruses, cytomegaloviruses, influenza viruses of various types and other pathogens.
Taking Amiksin can cause various dyspeptic symptoms, for example, a feeling of fullness in the stomach, abdominal discomfort, a feeling of bloating in the epigastric region, or nausea. Also, some children react to this medication with allergies and short-term chills.
Amiksin can be combined with any other drugs used in the treatment of viral infections. This drug is also well compatible with antibacterial agents. If it is given together with metronidazole drugs, their toxic effect on the liver is reduced.
The medicine Amiksin will help not only quickly cure a cold, but also prevent it. We live with a lack of sunlight and often experience hypothermia. It is no exaggeration to say that we are ideal victims of influenza and ARVI.
Therefore, it is doubly important for residents of our latitudes to strengthen their immunity: eat right, take vitamins, get plenty of rest, and walk in the fresh air. But in the rhythm of life of a modern person there is not always room for rest and walks.
Amiksin is an immunomodulatory drug; taking it not only shortens the time of illness with influenza and ARVI, but also prevents their occurrence. It has been proven that those taking Amiksin suffer from influenza and ARVI 3.4 times less.
Are you prone to colds? Have you had contact with someone sick with influenza or ARVI? Do you feel how your immunity decreases in the autumn-winter period? Then you should think about preventing influenza and ARVI with the immunomodulatory drug Amiksin!
The absence of serious adverse reactions is a feature of the drug Amiksin. And such side effects as chills, nausea, loss of appetite and stool upset are recorded quite rarely and do not require discontinuation of the drug.
Amiksin for influenza - description of the drug
Orange film-coated tablets, round, biconvex.
On the fracture it is orange, minor inclusions of orange and white are allowed. The main active ingredient of Amiksin is tyrolone, which promotes the production of interferon types a, b and g. This is a synthetic low-molecular drug that provokes the induction of natural interferon after oral administration. Due to this, the drug has a mild immunomodulatory and anti-inflammatory effect.
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Additional substances:
- Calcium hydrogen phosphate dihydrate;
- Microcrystalline cellulose;
- Calcium stearate;
- Povidone;
- Croscarmellose sodium;
- Titanium dioxide;
- Kandurin;
- Red synthetic dye;
- Yellow synthetic dye;
- Beeswax;
- Gelatin;
- Vaseline oil;
- Talc;
- Magnesium stearate basic;
- Aerosil;
- Confectionery sugar.
The round tablets are covered with a yellow film coating, orange at the break. They may contain 60 or 125 milligrams of the active substance, and are available in cardboard packages or plastic jars.
"Amiksin" and "Ingavirin"
Quite often, patients confuse Amiksin with Ingavirin, which is, in fact, its analogue. This can be explained by the fact that the drugs are similar in their composition and mechanism of action. It is difficult to determine which medication is more effective. This is due to the individuality of the patients’ bodies. Some patients are more susceptible to Amiksin, others to Ingavirin. Ingavirin, however, has an undoubted advantage - it actively fights viruses, which is due to the mechanism of its action. “Ingavirin” directly affects the virus, or more precisely, its RNA nucleotide. As a result, the virus loses its ability to reproduce. There are practically no differences in cost between the drugs.
The instructions for use for Amiksin 125 and 60 mg do not end there.
Cost of "Amiksin" and its analogues
The drug is freely available and can be purchased at almost every pharmacy. Its average cost is 500 rubles, but can reach 900 rubles. It all depends on the region of sale and the pharmacy chain that sells it. This cost of the drug may seem prohibitively high for many, but the effectiveness of the drug corresponds to its price.
The average cost of Amiksin in a dosage of 125 mg is 600 rubles per box containing 6 tablets. A package containing 10 tablets in the same dosage costs an average of 900 rubles. “Amiksin” with a dosage of 60 mg costs 550 rubles per plastic bottle or cardboard package (both forms of packaging contain 10 tablets).
The cost of the drug “Lavomax” with a dosage of 125 mg is 500 rubles per package containing 6 tablets. A pack of 10 tablets with a similar dosage costs about 720 rubles. The cost may vary depending on the manufacturer of the drug. The cheapest option is Lavomax, produced by.
Arbidol tablets in a dosage of 50 mg cost an average of 145 rubles per pack of 10 pieces. "Anaferon" has a price of approximately 105 rubles (the package contains 20 tablets).
The instructions for use for analogues of Amiksin will not be considered in detail.
Cheap analogues of Amiksin® in tablets
Complete structural analogues of this drug, that is, created on the basis of the same active substance, are:
- Tiloron® (10 capsules, 125 mg each);
- Lavomax® (3, 6 or 10 tablets with the same dosage);
- Tiloram® (6 and 10 tablets);
- Tilaxin® (10 tablets of 125 mg).
Each of the listed analogues of Amiksin® in tablets or capsules, like the original, is produced by domestic pharmaceutical companies. However, the price difference between them can be either minimal or quite significant. For example, Lavomax® produced by Nizhpharm® JSC costs about 450 rubles for 10 tablets, Tiloram® - more than 600 for the same quantity. The most budget-friendly substitute for Amiksin® is Tiloron in capsules for 130 rubles, produced by. Tilaxin® from Dalkhimfarm® is also inexpensive, and is offered in pharmacies at a price of 220 rubles.
Read further: List of the best antibiotics for ARVI in adults and children
Pharmacodynamics and pharmacokinetics
As the instructions for use for Amiksin indicate, the drug is capable of providing immunomodulatory and antiviral effects on the human body. That is, the effect of “Amiksin” is aimed not only at eliminating the viral infection, but also at increasing the overall human immunity at the cellular level. Under the influence of the drug, the content of B-lymphocytes and T-lymphocytes increases.
After oral administration of tablets, interferon production begins first in the intestines, then in the liver, and after 5-23 hours in the blood.
This is stated in the instructions for use of Amiksin 60 mg.
Absorption occurs in the gastrointestinal tract, the bioavailability of the active substance reaches 60%, and 80% binds to plasma proteins.
There is no biotransformation of the substance and its accumulation in the body.
The active component is excreted unchanged through the kidneys and intestines. The average time for removal of the active ingredient reaches two days.