Proginova maintaining a long-awaited pregnancy during IVF

Hormonal imbalance often causes infertility. To normalize hormonal levels, doctors prescribe hormonal medications to patients. One such medicine is Proginova. When planning a pregnancy, this drug has a positive effect on the state of the woman’s reproductive system, helps bring estrogen levels back to normal, and stimulates renewal of the endometrium of the uterus. When planning a pregnancy, Proginova will help a woman get pregnant faster. This drug has already helped many women with infertility become pregnant.

Proginova is one of the most common hormonal medications prescribed to combat infertility.

What is Proginova

Proginova is a hormonal drug that contains synthetic estrogens, similar to natural estradiol produced by the ovaries. Excipients are:

• corn starch;
• crystalline sucrose;
• lactose monohydrate;
• magnesium stearate;
• povidone;
• calcium carbonate precipitated.

Available in the form of dragees. One package of Proginov contains 21 tablets. The average cost in regular and online pharmacies ranges from 633 rubles to 874 rubles per blister.

Doctors do not recommend taking this drug on your own, as the consequences can be unpredictable and in some cases quite dangerous. This is especially true for women who dream of becoming mothers. Uncontrolled use of the drug can worsen the condition of hormonal levels and the reproductive system.

Analogs

There are several cheap analogues of Proginov. Since the main active ingredient of the drug is estradiol, Divigel and Estrocad are suitable replacements. In any case, before deciding to replace Proginva with an analogue, the approval of the attending physician is required.

The cheapest analogue of Proginov is Divigel.

Price of Proginov and analogues

Proginova is relatively expensive. The average price of the drug in a pharmacy is 650 rubles per package (2 mg tablets, 21 pieces). Analogues are much cheaper. For example, Divigel costs 450 rubles, and Estrocad from 250 rubles.

Indications

Lack of estradiol in the body is the main cause of problems with conception and pregnancy. Taking Proginov during planning helps improve fertility and normalize the functions of a woman’s reproductive system.

Many women who have problems conceiving are interested in the question of why Proginov is prescribed at the stage of pregnancy planning. This drug is used for hormone replacement therapy in women with severe estrogen deficiency in the body. This condition can be caused by the following ailments:

• infertility resulting from lack of ovulation, inadequate growth of the endometrium;
• chronic miscarriage;
• amenorrhea;
• scanty menstruation, meaning the fading of the ovaries;
• post-term pregnancy;
• hirsutism found in polycystic ovary syndrome;
• weakness of labor.

In gynecology, Proginov is used for:

• pregnancy planning;
• planning pregnancy through IVF;
• resection of 1 or 2 ovaries;
• breast cancer;
• suppression of lactation;
• normalization of hormonal levels;
• prevention of osteoporosis during menopause.

Cyclo-Proginova and conception

When preparing a woman’s body for conception, the doctor may prescribe several medications at once. Each of them has a specific effect on the ovaries. Proginova and Cyclo-Proginova have a similar name, but differ significantly in composition. Cyclo-Proginov is based on 2 hormones: progesterone and estradiol. Therefore, its effect on the female body is much more significant than that of monocomponent Proginova. If the patient is prescribed Cyclo-Proginova, then she does not need additional hormonal drugs.

Cyclo-Proginova is a drug with two active substances. When planning a pregnancy, this combination may be useful.

Indications for taking Cyclo-Proginov are the same as for Proginov. However, the treatment regimen will be different. This is due to the more complex composition of the drug.

The package of Cyclo-Proginova contains 21 tablets. The first dose is taken on day 5 of the cycle. A woman should start treatment with white tablets. They contain estrogen. White tablets are taken for 11 days. Then they begin to take light brown pellets. They contain progesterone. They need to be drunk for 10 days. When they end, the woman takes a week's break. If necessary, the course is repeated.

Impact on the female body

Proginova contains estradiol valerate, a synthetic estrogen that replaces a woman’s own estradiol in the body. A deficiency of this hormone leads to problems in the reproductive system, which is why pregnancy does not occur or miscarriage occurs.

Taking the drug at the stage of pregnancy planning in women of reproductive age does not cause inhibition of their own ovulatory function, while the synthesis of their own estrogens continues. Proginova has a beneficial effect on the condition of the skin and improves the condition of the endometrium. Thanks to these properties and the absence of other health problems, the chance of getting pregnant in the next menstrual cycle increases.

The use of medication during menopause helps eliminate the signs of this condition:

• relieves excessive sweating;
• lowers heart rate;
• relieves attacks of dizziness and weakness;
• improves sleep and mood;
• effective for the prevention of osteoporosis.

After entering the body, the drug has a positive effect on the condition of the mucous membranes and dermis, increasing their regeneration. This helps strengthen the skin, slow down the aging process and the appearance of crow's feet, and increase collagen in the skin.

The drug Proginova increases the chances of conception

Functions of Proginov in the body

Proginova refers to hormonal drugs containing estrogens. The drug contains an artificial hormone identical to the natural hormone of the female ovaries. In the body, the drug is converted into the hormone estradiol.

Proginova ideally replaces the lack of normal hormones that occurs in women during various periods (with natural or artificial menopause). In modern gynecology, Proginov tablets are prescribed for the successful conception of a baby. This remedy serves as an additional source of estrogen, causing women's ovaries to work more intensely and produce sex hormones.

This drug is prescribed in the following cases:

• For problems conceiving a child for women with too thin endometrium (to thicken and strengthen it). For conception, the thickness of the endometrium should not be less than 7-10 mm. With a thin endometrium (4-5 mm), it is impossible for the egg to implant, so pregnancy does not occur. The drug prepares the endometrial layer to react to progesterone.
• In the absence of ovulation. The drug ensures full ovulation if it was absent before treatment.
• With several failed pregnancies.
• With critically low estradiol levels. This hormone deficiency prevents the egg from leaving the follicle.
• After IVF as a supporting agent for better engraftment of the implanted embryo.

Thus, Proginova gives a chance to infertile couples and solves many problems that prevent women from getting pregnant.

Benefits when planning pregnancy

The drug Proginova is used frequently and successfully at the conception planning stage. As a rule, it is recommended to take it in the following cases:

• chronic lack of estrogen in the body;
• preparatory stage before IVF;
• history of spontaneous miscarriages;
• the need to build up the endometrium;
• improvement of placental blood supply.

One of the main causes of female infertility or miscarriage is insufficient thickness of the endometriotic layer. Proginova helps improve its growth, as a result of which the fertilized egg increases the possibility of attachment to the wall of the uterus with its subsequent development.

Synthetic estradiol, which is present in the medication, restores and normalizes hormonal levels. This helps eliminate many gynecological disorders and pathologies.

Estrogens stimulate the ovaries. After stopping the drug, women experience normal ovulation, making pregnancy possible in the first cycle.

After Proginov therapy, a noticeable improvement in the endometrioid layer is observed. Normal estrogen levels help cope with nervous disorders and regular migraines. As a rule, the drug Proginova is included in the list of mandatory medications for IVF.

When is it a good idea to add hormones?

Why can a doctor recommend Proginov? The drug is prescribed for the following purposes:

• to eliminate the estrogen deficiency condition caused by age-related decline of reproductive functions (if menopause is accompanied by hot flashes, headache, increased sweating, tachycardia, dizziness, sleep disorder, depression, dry skin, urinary incontinence);
• to compensate for the lack of estrogen after removal of both ovaries;
• to prevent the occurrence of osteoporosis, atherosclerosis caused by low estrogen levels;
• to stimulate reproductive functions, activate epithelial growth in the genital organs, restore normal endometrial thickness, improve metabolism;
• to prepare the body for conception and accelerate its onset;
• to normalize menstruation during scanty periods;
• in preparation for conception under the IVF program.

How to use

The regimen for taking Proginov at the stage of pregnancy planning has 2 types: continuous and cyclic. Continuous type means taking 1 tablet daily until they run out. After this, the next package begins to be taken, there are no breaks in use.

For the cyclic type, take 1 tablet until the blister runs out (21 days). After this, take a week's break and resume taking it.

Proginova should be taken at the same time of day, regardless of meals. The tablet is swallowed whole, without chewing, with water. It is forbidden to crush the medicine.

Much less often, a combination of drugs may be prescribed. The peculiarity of this method lies in the use of an additional medication that contains a gestagen, for example, Duphaston and Utrozhestan. As a rule, the dosage regimen looks like this: the patient takes both drugs for 14 days, after which he takes a break for 28 days. The duration of treatment is prescribed individually.

Remember, any omissions or errors in taking the drug can cause uterine bleeding.

If you are taking Proginova and become pregnant, you should not stop taking the drug. You should continue to take the drug until 8 weeks of pregnancy. This is especially true for women who have had early miscarriages.

How is Proginova useful during conception? The product helps saturate the placenta with oxygen and blood, preventing its rejection. From the 7th week of pregnancy, it is necessary to gradually discontinue the drug; abrupt cessation of use is unacceptable, as it can lead to spontaneous abortion. Sometimes doctors recommend drinking Proginova up to the 15th week of pregnancy inclusive.

Properties of the drug

The main active ingredient of Proginov is estradiol valeriat. It is a synthetic substitute for the natural female sex hormone estradiol. With the help of the drug, the deficiency of one’s own hormones is restored. In addition, the drug has the following positive properties:

• Does not suppress the ovulation process.
• It is highly effective.
• It has a small number of contraindications and side effects.
• Approved for use during in vitro fertilization protocol.
• Has a positive effect on the emotional background.

When planning a pregnancy, taking Proginov increases the chance of successful fertilization and the birth of a healthy baby.

Indications

The drug is prescribed for various conditions. The main indications for taking Proginov include:

• Infertility of various origins.
• Pathology of the menstrual cycle.
• Preparing for natural conception.
• Stimulation before the in vitro fertilization protocol.
• Relief of menopausal symptoms. Proginova reduces sweating, the severity of hot flashes, and has a calming effect.
• Prevention of osteoporosis. As women age, they are more likely to experience decreased bone density. This occurs due to a drop in estrogen levels. Taking the drug Proginova maintains normal levels of female sex hormones.

Contraindications

Before prescribing a drug, the doctor conducts the necessary amount of research. These include examination in a gynecological chair, mammography or ultrasound of the mammary glands, determination of blood pressure and glycemia, and a smear for cytology. It is necessary to start taking Proginova only after consulting with your doctor. The medicine is one of the hormonal drugs that affect the female body. Therefore, self-prescription of the drug should be excluded.

The main contraindications for taking Proginov are:

• Allergic reaction to the components of the drug.
• Age under 18 years.
• Lactation period.
• The presence of malignant oncological pathology.
• Heavy bleeding of various locations.
• Diabetes mellitus with complications.
• Acute pancreatitis, cholecystitis, as well as pathological conditions of the liver.
• Anemic syndrome.
• Onset of pregnancy.
• Thrombosis of the veins of the lower extremities.
• High blood pressure numbers.
• Mastopathy.
• Bronchial asthma.
• Autoimmune diseases.

Side effects

Despite the fact that Proginova is well tolerated and has a mild effect on a woman’s body, there are a small number of side effects. Their occurrence is associated with the individual reaction of the body to the drug. The main side effects when taking Proginov include:

• Pain in the heart area, rapid heartbeat.
• Pain in the abdomen, unstable stool, nausea and vomiting.
• Headache, dizziness, flashing spots.
• Increased irritability and anxiety, depression, decreased libido.
• Individual intolerance to components, which is expressed in an allergic reaction. Manifestations may include itching and redness of the skin.
• Metabolic disease. This side effect is characterized by weight gain or loss.
• Skin rashes. Acne, pimples, and male pattern hair appear.
• Enlargement and increased sensitivity of the mammary glands.
• Intermenstrual spotting.
• Irregularity in the duration of the menstrual cycle.
• Increased severity of premenstrual syndrome.

In what cases is pregnancy impossible?

Sometimes correct adherence to the instructions for use and doctor’s prescriptions does not bring the long-awaited conception. Typically, this condition indicates that:

• The body does not perceive the substances of the drug as a medicine.
• The patient has endocrine and gynecological disorders.

In these cases, the effect of using Proginov will be minimal. It will be necessary to conduct a more thorough examination, treat the existing ailments, and only then start using the drug. You can also initially choose another remedy instead of Proginov, the sensitivity to which will be higher.

The product has contraindications, you need to read them before taking it

Drug interactions

Hormonal contraceptives are canceled when taking hormone replacement drugs. If contraception is required, the doctor selects drugs from other medicinal groups. Additionally, take into account the influence of medications that are inducers of liver enzymes: they increase the clearance of sex hormones, reducing their therapeutic effect. This occurs 3 weeks after the start of treatment and lasts another 4 weeks after they are discontinued.

• Indications for hysterectomy, preparation for surgery and rehabilitation after hysterectomy
• Hormone replacement therapy
• Estradiol - what is it: the norm of the sex hormone in women

Contraindications

In certain situations, the use of the drug is unacceptable. Here they are:

• cardiac and vascular pathologies;
• endometriosis;
• various neoplasms, with the exception of breast cancer;
• diabetes;
• gallbladder pathology;
• liver diseases;
• simultaneous use with medications containing estradiol;
• age under 18 years;
• endometriosis;
• lactation period;
• undiagnosed uterine bleeding.

special instructions

It is important to monitor your health during hormone replacement therapy: the pills are canceled if a woman develops jaundice or phlebitis (inflammation of the veins), migraines worsen, heavy uterine bleeding begins, hearing or vision impairment, symptoms of thrombosis of arteries or veins, or kidney stones are observed. A few more nuances:

• During long-term estrogen therapy, gestagens should be taken in parallel to reduce the risk of endometrial cancer.
• If frequent but irregular bleeding from the vagina occurs during hormonal therapy, you must inform your doctor about this.
• If you plan to get tested, tell your doctor because estrogen replacement therapy may cause erroneous results on some laboratory tests.
• If pregnancy is suspected, Proginovaya is canceled unless the doctor decides otherwise.

Side effects

Some side effects may occur while taking Proginov. Here they are:

• decreased libido;
• flatulence;
• dizziness;
• tachycardia;
• sharp abdominal pain;
• feeling of heaviness in the stomach;
• apathy;
• infrequent pain in the lower abdomen;
• enlargement of the mammary glands;
• amenorrhea;
• sudden weight gain;
• skin rashes;
• blood pressure surges;
• increased breast sensitivity;
• migraine;
• intolerance to contact lenses;
• fatigue;
• increase in tumors in the mammary glands.

If one or more of the above symptoms appear, you should consult your doctor. As a rule, when these symptoms are identified, the doctor stops the medication and prescribes symptomatic therapy aimed at maintaining the basic functions of the body.

If irregular intermenstrual discharge occurs, diagnostic curettage of the uterus is prescribed to exclude a neoplasm in its cavity.

When should I stop taking the medicine?

Like any hormonal drug, Proginova can provoke undesirable effects, which is grounds for immediate cessation of use. This:

• the appearance or exacerbation of migraine;
• intense headaches;
• decreased vision or hearing;
• signs of jaundice;
• muscle pain;
• vaginal bleeding;
• symptoms indicating venous thrombosis: swelling of the extremities, shortness of breath, cough with blood, chest pain.

Treatment is sometimes accompanied by increased gas formation, stomach discomfort, rashes, swelling of the mammary glands, increased or decreased libido, apathy, and changes in blood pressure.

Reviews

We invite you to read reviews from doctors and women about the drug Proginova.

Nina, gynecologist

Proginova is an effective remedy, the use of which promotes conception. I recommend it to women who are experiencing difficulties with pregnancy. At the same time, the product has a number of side effects that should be familiarized with before use.

Valentina, endocrinologist

I often see women who cannot get pregnant. This is usually due to disruption of the endocrine system. After their treatment and taking the drug Proginova, pregnancy occurs almost immediately. I would like to note that at the planning stage it is also recommended to drink folic acid.

Polina, 29 years old

I took Proginova several courses, 2 tablets per day. I didn’t believe in the effectiveness of the drug, but I still managed to get pregnant. No side effects were observed while taking the drug.

Irina, 32 years old

Personally, Proginova did not help me get pregnant. It only caused skin rashes and migraines. I do not recommend this drug.

You can use Proginov only after a doctor's prescription. Self-administration is unacceptable, as it can lead to a number of negative consequences and hormonal imbalances.

Hormones are not scary! Studying reviews

Reviews of the results of using Proginov left by women confirm that this is a high-quality and fairly safe drug. He helped many realize their dream of motherhood, as the examination showed that against his background there was good growth of the endometrium. Moreover, taking the medicine was not accompanied by weight gain or other unpleasant side effects. But in some patients it still caused headaches.

This remedy is also positively assessed by those who used it to escape the painful symptoms of menopause. Women write that it literally brought them back to life, got rid of hot flashes, improved their mood, and normalized their sleep.

Despite all the positive effects, hormone treatment is not the same as taking a valerian pill. Even the best drug of this spectrum can cause serious problems. Thus, with prolonged use of Proginov, the risk of developing breast and ovarian cancer increases. Therefore, it should be taken as prescribed and under the supervision of a doctor. This is the only way to count on a positive result without unpleasant surprises.

Taking with other medications

This drug, when taken with other tablets, often gives a positive result. It can be combined with a course of taking Duphaston or other medications that contain the hormonal compound progesterone. If you need to do some laboratory tests while taking Proginov, their readings may be somewhat distorted.

Taking the drug should be isolated from the use of contraceptives. In this case, it is advisable to temporarily stop taking the latter. In such cases, it is best to use non-hormonal methods of contraception.

Some antibiotics, once in the female body, can lead to a decrease in the amount of estradiol molecules in the blood. Therefore, simultaneous use of Proginov tablets and these antibiotics should be stopped.

Taking a certain category of medications may negatively affect the effectiveness of the enzymes produced. Typically, such drugs affect the initiation processes of enzymatic molecules in the liver. As a result, it is possible to increase the clearance of hormonal molecules, but with a reduced efficiency. Therefore, before taking this medication, it is recommended to undergo an appropriate examination, based on the results of which it will be possible to identify the combination of medications taken.

The benefits of Proginov tablets have already been identified by scientists from around the world. Only when taking this medicine, you should follow some recommendations so as not to cause harm to your body instead of benefit.

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It is not recommended to take this medicine if a person has previously consumed alcohol-containing products. The combination of these two components can have a detrimental effect on the patient’s condition, namely:

• The medicine, drunk together with a large amount of alcoholic beverages, promotes a rapid increase in the bloodstream of a hormone such as estradiol, which in the female body regulates the frequency of menstruation. If the level of the hormone is sharply increased, this can lead to the development of many diseases and deterioration in a woman’s appearance.
• In addition to increasing hormone levels, negative consequences from taking alcohol-containing products can affect the gastric mucosa.
• Also, the combined use of these components puts additional stress on the cells of the kidneys and liver, which are already stressed due to taking the drug.

From all of the above, the conclusion suggests itself that the presented medicinal product is not compatible with alcoholic beverages. You should remember this and try to refrain from taking ethanol for the entire course of hormone treatment.

Efficiency

reproductive system
However, the main property of the hormonal drug is the normalization of estrogen, a hormone that plays a key role in conception and enables women to become mothers.

The effectiveness of Proginova is manifested in the following factors:

• improvement of cell regeneration;
• elimination of inhibition of one’s own ovulatory function;
• beneficial effects on the nervous system;
• improvement of the inner layer of the uterus;
• normalization of the menstrual cycle.

IMPORTANT! Uncontrolled use of Proginov can cause the opposite effect. The hormonal balance will be disrupted, and the functionality of the reproductive system will become inferior

The drug should be taken only if indicated and recommended by a doctor.

Pharmacodynamics and pharmacokinetics

pituitary tumors; pathologies accompanied by thrombus formation in the deep veins (also in cases where these pathologies are noted in the anamnesis);

But when the required doses are exceeded, the secretion of gonadotropins is inhibited.

After confirmed ovulation, pregnancy tests are not recommended for 12 days, as the result may be false negative.

Pregnancy. Pipe factor. Normal tubal patency is very important when planning pregnancy, so a woman needs to undergo a special examination before stimulation. tubal infertility>

In addition, adverse reactions may include the appearance of “hot flashes” in the face, weight gain, pain in the mammary glands, alopecia and a slight decrease in visual acuity.

2 weeks (on the 14th day) after ovulation, a woman’s blood is taken to determine the level of hCG and the presence of pregnancy.

Diagnosis of the disease before conception includes analysis of symptoms, identification of the presence of spontaneous abortions, and inflammation of the appendages. An endometrial biopsy, hysteroscopy (examination of the uterus using optics), and ultrasound are also performed.

Use of the drug for alcoholism

If the patient suffers from alcoholism, inflammatory liver diseases quickly occur, hepatitis, fibrosis, and cirrhosis appear. These pathologies are contraindications for taking the drug.

With chronic alcoholism, kidney failure gradually occurs. It also refers to contraindications for hormonal therapy.

Alcoholism often disrupts fat metabolism and causes inflammatory diseases of the digestive tract. These conditions are not comparable to taking estradiol. Chronic diseases can worsen, causing a deterioration in a person’s well-being.

Proginova. Instructions for use

Proginova is a hormonal drug that contains estrogen, which is as close as possible to the natural hormone. Normally, it is regularly produced in the female body by the ovaries. If there is insufficient production of this hormone, there is a need to replenish its deficiency. The drug Proginova can cope with this task.

The wide spectrum of action of the hormonal drug allows you to eliminate most women's problems. So, Proginov’s main task is to relieve a woman of unpleasant sensations during menopause. By the age of 50, the ovaries are unable to produce estrogen, so gynecologists can prescribe replacement therapy to relieve a woman of such unpleasant symptoms as sweating, sudden sensations of heat or cold, irritability, sleep disturbances, headaches and other “delights” of the onset of menopause.

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In addition, a hormonal drug is also necessary if a woman does not have ovaries, as well as to prevent the development of osteoporosis.

Venous thromboembolism

Oral contraceptives Proginova are very often prescribed to patients suffering from venous thromboembolism. The drug is taken under the strict supervision of the attending physician.

Before starting therapy, a woman should find out as much information as possible about the disease in order to determine the risks that may arise during treatment. After carefully studying such issues, the patient makes a decision and starts taking the drug. The reasons why the disease may occur are as follows:

• personal or family history;
• excess weight.

If the patient experiences clinical manifestations of venous thromboembolism during treatment with the drug, therapy is stopped. Neglecting this recommendation can cause irreparable harm to the female body.

Alcohol, contraceptives and pregnancy

A combination such as alcohol and Proginova can be very dangerous for the female body. Alcohol, at certain exposure levels, is a stimulant of liver enzymes. As a result of this action, the liver will more quickly metabolize the oral contraceptives that the woman is taking.

The first reason for taking it is to protect yourself from unwanted pregnancy. During simultaneous use of oral contraceptives and alcohol, the concentration of the drug decreases. The substances are metabolized and an unwanted pregnancy occurs. There is also a change in the lipid spectrum. Oral contraceptives are completely unsafe in this regard. The spectrum of hemocoagulation changes.

Who is contraindicated for taking Proginov?

Hormonal drugs are never taken without a doctor's prescription. Self-medication can lead to unpredictable consequences. Before prescribing Proginov to a patient, the doctor performs a thorough examination, finds out the presence of chronic diseases, examines her mammary glands, measures blood pressure, prescribes tests to determine blood sugar levels, and performs colpocytodiagnosis. The drug is contraindicated in the following cases:

• age less than 18 years;
• individual intolerance to Proginov components;
• pregnancy (if there are no indications for prescribing medication);
• uterine, vaginal bleeding;
• suspicion of breast cancer;
• vein thrombosis;
• cardiovascular pathologies (heart attack or stroke);
• breastfeeding period;
• severe pathologies of the liver and gall bladder;
• pancreatitis;
• severe diabetes;
• anemia.

In addition, there are a number of conditions when a hormonal drug is prescribed with caution:

• tendency to increase blood pressure;
• diabetes;
• mastopathy;
• epilepsy;
• endometriosis;
• bronchial asthma;
• systemic lupus erythematosus;
• uterine fibroids;
• increased bilirubin levels.

What medicine can be replaced

If for some reason the use of this medication is impossible, then it must be replaced by another from a wide range of structural and functional analogues. So, in some cases, when therapy is ineffective, doctors say that Proginova does not work due to the woman’s lack of sensitivity to it. In others, unacceptable adverse reactions may occur.

Proginova has the following analogs for the active component:

• Divigel;
• Estrogel;
• Klimara;

Their active ingredient is estradiol. They differ in the form of release and the proposed concentration of the substance. Their functions and limitations in use are similar.

Functionally similar to the drug Proginova are:

• Ovestin;
• Klymen;
• Sinestrol.

Ovestin contains estriol, and this medicine is intended for the treatment of infertility caused by the cervical factor. Climen, like Cyclo-Proginova, is presented in two types of pills: with one estrogen in the composition and with estrogen plus an antiandrogen. Klimen normalizes the menstrual cycle. Sinestrol does not belong to the group of steroidal estrogenic hormones, but its structure is very close to them. It can be used for infertility and weak labor.

Table: Proginova and analogues

Active ingredient	Release forms	Manufacturer	price, rub.
Proginova	Estradiol valerate.	Dragee.	Bayer Pharma AG (Germany).	From 588 for 21 pieces (2 mg).
Cyclo-Proginova	estradiol; estradiol plus norgestrel.	white jelly beans; light brown jelly beans.	Bayer Pharma AG (Germany).	From 936 for 21 pieces.
Divigel	Estradiol.	Gel (0.1%).	Orion Corporation (Finland).	From 646 per pack.
Estrogel	Estradiol hemihydrate.	Gel.	"Bezen Manufacturing Belgium" (Belgium).	From 738 per tube.
Klimara	Estradiol hemihydrate.	Therapeutic system in the form of a patch.	Bayer Pharma AG (Germany).	From 1213 for 4 units.
Ovestin	Estriol.	pills; vaginal suppositories; cream.	"N.V.Organon" (Netherlands).	From 1156 for 30 tablets (2 mg).
Klymen	estradiol valerate; estradiol valerate plus cyproterone acetate.	There are two types of dragees.	Bayer Pharma AG (Germany).	From 1249 for 21 pieces.
Sinestrol	Hexestrol.	Solution for injection in ampoules.	"Dalkhimfarm" (Russia).	From 649 for 10 ampoules.

Photo: options for replacing the drug Proginova

In my life, I, my wife and our friends have never had to face the need to use estrogen-containing medications. Many people used drugs with artificial progesterone both during gestation and when planning a child. Moreover, in the second situation, not everyone was successful. While studying the topic of treatment with such a remedy as Proginova, I was faced with a lack of information on any research. Most fertility doctors on medical forums talk about how the thickness of the endometrium of the uterus increases with the help of this medicine, but no one evaluates the effectiveness of such therapy for infertility. In general phrases, it is reported that with proper treatment, Proginova can bring the desired pregnancy after the first therapeutic course. And according to reviews from women who have taken this drug, everything turns out to be not so rosy. Yes, in most cases the endometrium thickens as a result of treatment, but pregnancy does not occur. With such outcomes, doctors say that the medication was not suitable, or begin to look for other pathologies. In general, my opinion about this estrogen-containing product is ambiguous. Most domestic doctors recommend it, but there is little evidence of effectiveness and safety. I would like modern medicine to advance further in this matter.

With IVF

IVF is a complex procedure that requires extensive preparation. Women are prescribed special examinations and drug therapy. Proginova is recommended in most such cases: it prepares the body and all its internal systems for a potential pregnancy, activates natural processes and eliminates the risk of fetal rejection.

The effect of the drug when taken at the preparatory stage for IVF:

• eliminating the possibility of fluctuations in estrogen levels;
• ensures a uniform hormonal replacement level;
• the likelihood of a favorable pregnancy and quick conception increases.

REFERENCE! When taking a hormonal drug at the stage of preparation for IVF, the dosage and regimen remain unchanged. In rare cases, a specialist may cancel the course of treatment only in the tenth week of pregnancy. Before conception occurs, you must take the pills continuously.

Treatment of various pathological processes

Proginova is often prescribed to women who suffer from a lack of female hormones in the body. This phenomenon often occurs in patients after the appearance of various pathologies. Hormonal contraceptives are suitable for the treatment of the following disorders:

• infertility;
• increased growth of unwanted vegetation on the body;
• treatment of various ovarian diseases;
• preparing the body for bearing a child after the IVF procedure;
• disruption of the normal rhythm of the menstrual cycle;
• preventive measures for symptoms of osteoporosis in the post-climactic stage;
• excessive hair loss.

With the help of the drug, many disorders of the female body are treated.

A course of treatment

The attending physician prepares therapy exclusively on an individual basis. There are the following admission courses:

With the help of Proginov, it is customary to treat many pathological conditions in women. However, we should not forget that the medicine should never be used as self-medication. Treatment is prescribed by a doctor after a thorough examination and examination of a number of tests.

The danger of the medicine lies in its continuous and long-term use. Experienced specialists always pay attention to this fact. You should not start therapy without consulting a doctor and his recommendations for treatment. Neglecting these tips can cause serious harm to your health.