Berodual: indications for use, dosage and analogues of the drug

Side effects

Berodual has special properties - beta-adrenergic and anticholinergic.
They are the ones that can cause complications. First of all, irritation in the throat may appear. Patients often complain of nervousness, cough, development of pharyngitis, dry mouth, and increased blood pressure. Sometimes frequent headaches and dizziness, vomiting, and dysphonia are observed. There is also information that hypokalemia, anaphylactic shock, diarrhea, urinary retention, corneal edema and other complications may develop.

If any of the side effects presented are present, Berodual is canceled and its analogues are offered. The main thing is to choose a drug that completely minimizes all negative reactions and will replicate the therapeutic effect of Berodual as much as possible.

Side effects

Berodual often causes side effects, especially if used in high doses and often. The most common adverse events that occur can be identified as follows:

• dry mouth;
• headache;
• trembling in the limbs;
• dyspeptic symptoms;
• inflammation of the pharynx;
• increased nervousness;
• increase in pressure.

Often, after inhalation with Berodual, stomatitis or glossitis begins . In addition, there may be swelling of the oral mucosa.

If any side effects appear, stop using the drug and consult a doctor.

Indications for use

The medicine is used for broncho-obstructive syndrome - a phenomenon in which narrowing and spasm of the small bronchi occurs, as a result of which the patency of the respiratory tube is disrupted.

This condition most often occurs in infants, young children and preschoolers. In infants, bronchospasm can be caused by the peculiarities of the anatomical and physiological structure of babies, in which any inflammatory process can provoke swelling of the walls of the bronchial tree and their narrowing.

The medicine should be used with extreme caution to treat children, as even minor deviations from the doctor’s recommendations can lead to negative side effects.

At an older age, bronchial obstruction may develop in children due to hyperreactivity of the bronchioles caused by increased sensitivity of the autonomic system.

In adults, broncho-obstructive syndrome can occur against the background of severe bronchopulmonary diseases (pneumonia, tuberculosis, asthma, etc.).

When is Berodual prescribed:

• Bronchial asthma;
• Obstructive bronchitis;
• Emphysema;
• Pneumonia;
• Chronic obstructive pulmonary disease.

For what cough is Berodual prescribed? For a cough that occurs as a result of infectious and non-infectious respiratory pathologies, accompanied by narrowing (obstruction) of the airways.

But not every type of cough is an indication for using the drug, and if the drug is used for other purposes, it can seriously harm your health. Even if Berodual was previously used for treatment, you cannot prescribe the medication yourself.

Application of Berodual:

• Bronchitis. The medicine is not mandatory in the treatment of bronchitis and is used only when bronchial obstruction develops: in the presence of severe wheezing, difficulty in breathing. If these symptoms are not present or are not pronounced, then it is enough to use expectorants. In severe forms of bronchitis, simultaneous use of Lazolvan and Berodual is possible, and in case of severe obstruction, a stronger drug is recommended (for example, Pulmicor).
• Pneumonia. First of all, antibacterial drugs are prescribed for the treatment of pneumonia, and expectorants and mucolytics are prescribed to improve drainage of the lungs and bronchi. Berodual is used for pneumonia to provide symptomatic treatment of bronchospasm accompanying pneumonia.
• Laryngitis. If laryngitis is accompanied by difficulty breathing, then Berodual is prescribed for treatment. But the drug does not always help to cope with swelling of the larynx, therefore, for laryngitis, complex treatment with Pulmicort and Berodual is possible.
• Dry cough. Berodual is not an antitussive and therefore is not used for dry coughs unless the latter is caused by asthmatic phenomena.
• Choking cough. This type of cough is most often caused by obstructive phenomena, so Berodual is used to relieve such symptoms.

Whether the patient has bronchial obstruction is determined only by the doctor. The main signs of bronchial obstruction are: dry (allergic) cough, barking cough, rapid breathing, prolonged inhalation, attacks of lack of air.

The effectiveness of using "Berodual" for inhalation: medicinal properties

The main property of this drug is the ability to quickly and effectively relieve spasms of the bronchial tree and trachea. The oxygen supply to tissues is improved and the risk of carbon dioxide accumulation is reduced. Efficiency has been proven by practical and clinical trials. Correct use of Berodual for inhalation can reduce the number and duration of coughing attacks. We will talk further about what medicinal properties make it possible to achieve such an effect.

But first, it’s worth clarifying that the pharmacological industry produces two dosage forms: a ready-made spray in a bottle with a spray bottle and a solution for dosing at home. For children, it is advisable to use a solution with the addition of saline. An adult can use a ready-made inhaler. The drug belongs to the group of bronchodilators; it contains two active components: ipratropium bromide and Fenoterolum. The first component is responsible for blocking the irritant effect on cholinergic receptors. The degree of irritation of the vagus nerve decreases. The cough reflex is blocked. The production of mucous secretions in the bronchial tree decreases. The effect of ipratropium is exclusively local; it does not affect the process of evacuation of secreted sputum, but stimulates the work of the ciliated epithelium.

Fenoterol has a positive effect on stimulating the performance of b2-adrenergic receptors while simultaneously operating b1-adrenergic receptors. As a result, it reduces the sensitivity threshold of receptors, reducing the level of histamine and various forms of methacholines.

The pharmacological effect is local and begins immediately after the active components enter the mucous membranes of the respiratory tract. Chemical reactions occur in areas of inflammation and the bronchospastic effect is eliminated. After blocking mast cells, the swelling of the mucous membrane decreases, and the lumen of the bronchi increases. You should be very careful when calculating proportions and dosage, since at high concentrations there is a high clearance of the mucolytic process. The amount of expectorated sputum increases, which provokes an increase in coughing attacks.

The drug "Berodual" even in inhalations tends to affect the performance of the cardiovascular system. An increased heart rate is often a side effect. The second most common side effect is tremor of the upper extremities.

Advantages of the drug

Berodual is an effective remedy regardless of the form of release. It is the inhalation supply of the drug that is most suitable for the treatment of the lower parts of the respiratory system. Therapeutic vapors are quickly delivered to their destination, clearly performing their function.

• Children and adults easily perform procedures using a nebulizer, even finding some interest in it. As for spray cans, you will have to learn a little. The doctor always demonstrates to the patient how to take breaths, and after just a few breaths the patient succeeds. Children also cope with this task easily.
• The effectiveness of the drug occurs within 15–20 minutes, and the patient immediately feels that breathing becomes much easier. 2 hours after inhalation or inhalation with a balloon, the greatest opening of the bronchi occurs, and this continues for up to 6 hours. Then inhalations are repeated.
• Under the influence of Berodual, bronchospasm is relieved, and this is the most important thing in the treatment of bronchial asthma and chronic obstructive pulmonary diseases. Berodual stimulates breathing, relaxes the smooth muscles of the bronchi, and also reduces the secretion of the glands.

The drug can be used as monotherapy, but more often it is used in complex treatment regimens for bronchopulmonary pathologies. With reasonable use of Berodual, and compliance with all doctor’s instructions, the drug brings only a positive therapeutic effect.

Pharmacokinetics

Ipratropium bromide monohydrate binds to their receptors in the respiratory tract and improves the tone of the respiratory muscles. In addition, the active ingredient reduces the release in the body of agents that contribute to the narrowing of the airways. Thus, the bronchi expand, and due to this, breathing improves.

Fenoterol affects the smooth muscles of the bronchi and prevents the development of bronchospasms. Immediately after administration, the substance blocks the generation of mediators of inflammation and bronchial obstruction. The use of fenoterol also helps to increase mucociliary clearance (the mechanism of protection of the mucous membrane of the respiratory tract from external influences).

How to breed berodual instructions for children and adults

We have already said that berodual has two forms.

1. The first is a can; its contents do not need to be diluted with anything, i.e. follow the instructions and inhale the healing vapors. Usually several breaths are used at a time, and so on three times a day. The main thing is to inhale correctly so that all the medicine does not remain on the tongue, but gets into the respiratory tract.
2. The second form is a solution for inhalation.

It should be immediately noted that the instructions for use warn that Berodual is prescribed to children only after 6 years of age, and body weight should exceed 22 kg. This is due to insufficient research at this age. But, in practice, in hospital settings, berodual is still used for smaller patients.

Then, per 1 kg of the child’s weight, the following calculation is used: 25 mcg of ipratropium bromide and 50 mcg of fenoterol hydrobromide. “How many drops of berodual will this be?” – many mothers will ask. The answer is: 1 drop per 2 kg of baby’s body weight.

We already understand how much berodual we need for inhalation, now we’ll figure it out further. Procedures are performed up to six times a day (according to strict instructions), using 10 drops per inhalation, but do not forget that this dose is allowed according to the instructions. One milliliter corresponds to 20 drops of solution, i.e. 0.5 ml = 10 drops. It is easy to calculate the daily dose; it is equal to 30 drops or 1.5 ml of Berodual solution.

It is better to start any treatment with minimal doses to see how the patient reacts to the medicine. The first procedures are carried out twice a day.

For example, if the baby weighs 6 kg, then we will need 3 drops of Berodual solution and 3 ml of saline solution. The drug must be diluted. In some cases, after berodual, the doctor may prescribe additional inhalations with lazolvan or another expectorant.

Inhalation courses last about five days, but as directed by a doctor they can be carried out for a longer period. You also need to pay attention to the dosage of Berodual depending on the severity of the process in the patient. For moderate bronchospasm, 10 drops are enough per inhalation

When mild or moderate attacks of bronchial asthma occur, the dose is increased to 20 drops per inhalation. For severe and especially severe attacks, the dose is from 50 to 80 drops. Long-term course treatment for adult patients requires the following dosage - 20-40 drops 3-4 times a day.

If you notice that during the first inhalations there is a cough, soreness, or swelling in the throat, immediately inform your doctor about this, the drug is clearly not suitable, it must be urgently changed to an analogue.

Rules of application

"Berodual" is a mucolytic drug with expectorant properties. Approved for use in the form of inhalations. The effectiveness of the drug increases as a result of the use of a nebulizer. A steam inhaler is not suitable for treatment. Otherwise, a negative reaction from the body’s respiratory system may occur: burns, irritation of the mucous membranes, cough and chest pain.

See also

Instructions for use of the drug "Gentamicin" for inhalation, side effects and contraindications

Read

For babies

Newborn children undergo therapy exclusively in a hospital setting. "Berodual" is used under the supervision of a doctor, as it is considered strong for a young age. The procedure takes on average about 6 minutes. After its completion, the child is under supervision for 1-1.5 hours. If the body reacts to inhalation in the form of adverse reactions, the baby is given first aid.

Children under 1 year and older

This age category of patients requires compliance with the main point in treatment - taking into account body weight. A drop of the drug is enough for 2 kg of weight. The inhalation procedure requires 7 to 10 drops of the substance. As an additional component, saline solution in a volume of 2 mg is used. Also observe breaks between inhalations.

For adults

The body of an adult is quite strong and needs an increased dose of medicine, unlike children. The recommended starting dose is 15 drops. To reduce the concentration of the substance, take only 10 drops of Berodual. If the resulting solution produces the desired therapeutic effect, there is no need to increase the dose.

The dosage is calculated according to the same principle as for a child. The maximum number of drops per day should not exceed 80. After recovery, it is recommended to continue the course of treatment. In this case, the dosage is reduced to 40 drops.

During pregnancy and lactation

Therapy in women begins with lighter drugs. If the disease becomes persistent, proceed to the use of Berodual. Inhalations are indicated for pregnant women between 4 and 6 months of pregnancy. The steps of the procedure are exactly the same as for adults.

The drug is contraindicated in the last month of pregnancy. The components in the composition negatively affect the tone of the uterus, disrupting the natural process of childbirth. The use of Berodual in the first trimester may result in a miscarriage. Breastfeeding women should consult their doctor.

Inhalations with Berodual: rules of use

Berodual solution is used for inhalation using a nebulizer. The drops themselves are not used in their pure form, i.e. the medicine must be diluted with saline, mixing both products in the required proportions.

Inhalations for children under one year of age are carried out only in hospital conditions and under the supervision of a doctor. Older patients can carry out the procedure at home, but also under the guidance of doctors.

How to dilute the solution

Berodual solution cannot be diluted with distilled or other water, because this can lead to dry mucous membranes and increased coughing, and make the inhalation procedure itself unpleasant and painful.

How to dilute Berodual for inhalation:

• Measure the required dosage of Berodual drops into a measuring cup.
• Bring the liquid volume to 4 ml with saline solution.

Before each inhalation, a fresh solution is prepared. And the excess of the remaining diluted solution is disposed of - it cannot be reused.

Composition and form for inhalation therapy

"Berodual" is presented in different dosage forms. There are solutions and aerosols for inhalation. The spray bottle has a volume of 10 ml. This quantity is enough for 200 doses.

The drug in the form of a solution is intended for steam inhalation using a nebulizer. For one session you will need a few drops of liquid. The consumption is very economical. Berodual is not used in its pure form. A special solution is made according to a prescription prescribed by the attending physician.

The basis of the drug consists of two components - ipratropium bromide and fenoterol. Substances with bronchodilator properties have a positive effect on diseases of various natures. No steroids are used in the creation of Berodual. Therefore, it is not included in the group of hormonal drugs and is used quite widely in medical practice. But it is indicated for treatment only as prescribed by a doctor.

Analogues and compatibility with other drugs

Berodual can be bought without a doctor's prescription, but before purchasing the medicine yourself, you should still consult with a medical professional. The average price of the drug in Russian pharmacies is from 275 rubles. for a bottle of solution.

In the absence of Berodual, the medicine can be replaced with one of the analogues: Berotex, Duolin, Ventolin, Salbutamol, Salbroxol, Ipraterol-native. All of these drugs are bronchodilators of various types and are intended for inhalation administration, but the specifics of their use and dosage must be checked with a doctor for each specific case.

Analogs of the drug Berodual can be used only on the recommendation of a doctor.

In addition, the doctor may prescribe other medications to treat broncho-obstructive syndrome. The most commonly prescribed combinations are: Berodual and Pulmicort or Berodual and Lazolvan, but it all depends on the clinical situation. Such combinations combine the therapeutic effects of both drugs used, which makes it possible to eliminate even the most severe attacks of chronic obstructive pulmonary disease and bronchial asthma.

When prescribing a therapeutic course with the use of other drugs, it should be taken into account that Berodual cannot be combined with all drugs:

Anticholinergic substances + Berodual. Not recommended for use together. Xanthine derivatives, beta-adrenergic agonists, anticholinergics for systemic use + Berodual. Strengthen the bronchodilator effect, increase the risk of complications and adverse reactions. Diuretics, xanthine derivatives, beta-agonists, corticosteroids + Berodual. Increased hypokalemia. Tricyclic antidepressants, MAO inhibitors + Berodual

The combination should be used with caution.

Reviews of the use of Berodual for children and adults are positive: pediatricians and pulmonologists note that with the help of the medicine, attacks of bronchial asthma are quickly stopped, and with a course of taking it for several days, it is possible to completely eliminate all symptoms of bronchospasm. The patient's dry wheezing disappears and a wet cough appears, and the drainage of the tracheobronchial tree is restored.

In addition, the nebulizer is very convenient for everyday use and its use does not require any special medical knowledge, and the simplicity of the inhalation procedure allows Berodual to be prescribed even to young children.

Release form and composition of Berodual for inhalation

The drug Berodual for inhalation is available on the pharmacological market in two forms of release - a solution for inhalation and a pocket aerosol inhaler. This drug is very convenient to use and is a leader in sales among drugs with a similar effect.

Berodual Inhaler

The Berodual inhaler is a metered canister with a special nozzle for spraying. One click - one dose. The drug can be used by adults or for children over 6 years of age. The maximum daily dose should not exceed 8 single administrations.

A more popular solution is Berodual for inhalation, which can be administered into the respiratory system using a nebulizer. A solution is available in a 20 ml bottle containing 400 drops. The bottle has a convenient dispenser, which allows you to use the drug without exceeding the dose.

For inhalation, Berodual must be diluted with saline solution. Dosages are prescribed by the doctor individually for each patient. For inhalation procedures, you need to use a compressor or membrane nebulizer.

Features of application

Side effects may occur during inhalation. The most common symptoms are chapped lips and dry mouth. Therefore, after the procedure, the patient is recommended to wipe his mouth with a damp cloth and lightly moisten the oral cavity with a sip of water to rinse off the solution.

Other possible side effects:

• Decreased blood pressure;
• Hand tremors;
• Tachycardia;
• Headache;
• Skeletal muscle spasm;
• Nervousness;
• Dizziness;
• Vomiting, diarrhea, nausea;
• Urinary retention.

In case of an overdose of the drug, allergic reactions may occur in the form of urticaria and swelling of the mucous membrane, as well as increased heart rate, chest pain, and increased bronchospasm. In this case, you must immediately stop the procedure and seek medical help.

Inhalation for children is carried out in the same way as for adults, the only difference being that the concentration of berodual in the nebulizer is lower and constant monitoring by an adult is required

Berodual inhalation solution for children should be used with extreme caution, because even small deviations from the dosage and medical recommendations can lead to the development of negative consequences

Precautionary measures:

• It is prohibited to use Berodual solution without an inhaler.
• It is prohibited to take the medicine internally.
• You cannot inhale the solution at home (without a nebulizer). Contact of solution vapors in the eyes can cause irritation and pain in the eyes, and even provoke glaucoma.
• Pregnant women should only inhale Berodual under medical supervision. The drug has a depressing effect on the contractile function of the uterus. Therefore, it is allowed to be used only from the second trimester of pregnancy.

Berodual should not be used:

• In case of individual intolerance to the components;
• For cardiomyopathy;
• For heart rhythm disturbances;
• For glaucoma;
• For diabetes mellitus;
• For severe heart pathologies;
• For cystic fibrosis.

Berodual should be used with caution for high blood pressure, in the second trimester of pregnancy, and for venous diseases.

Contraindications

Although Berodual for inhalation is not a hormonal drug, it also has many contraindications. The medicine should not be taken in the following cases:

• in case of intolerance to individual components that are part of the medicine;
• chronic heart disease;
• first and third trimesters of pregnancy.

Berodual is prescribed with great caution for glaucoma, heart failure, diabetes, benign and malignant tumors.

The drug should not be prescribed during the recovery period after a stroke or heart attack!

Important points when performing inhalations with Berodual

If the doctor has prescribed a certain dose, we follow the recommendations. Sometimes the patient gets scared when the doctor immediately gives a loading dose. Every patient should understand that it is impossible to stop attacks of severe bronchospasms with small doses of Berodual. Therefore, do not panic; in the future, the dose of the drug will be reduced.

Berodual should be diluted only with physiology (0.9% sodium chloride solution). The volume is adjusted to 3–4 ml, no more is needed. Inhalation continues until all the solution has dissolved. Distilled water is absolutely not suitable for dissolving berodual.

Also note that if you interrupt the procedure and a solution remains, it is no longer suitable for subsequent inhalations. For each individual inhalation, only a fresh solution is prepared, and only before the procedure itself

The duration of the procedure is usually no more than 10 minutes. It all depends on the nebulizer, or what method the patient uses for treatment. But we clearly know that the solution must completely evaporate, only then we finish the treatment.

Patients should never exceed prescribed doses. This may worsen the course of the disease. In some cases it is even dangerous. Increasing uncontrolled doses of Berodual can lead to the most irreparable complications, so we listen only to the treating doctor.

We recommend reading: how to inhale with Pulmicort.

Berodual for inhalation with a nebulizer instructions

The first procedure is best done under the supervision of an experienced specialist in a medical office. To administer the medicine by aerosol it is necessary to use an inhaler - nebulizer. The device “breaks” the medicine into the finest particles and delivers them directly to the lungs as you inhale.

1. It is necessary to bring the device into working condition - but not turn it on
2. Drop the required dose of Berodual into the container, diluting if necessary with a solution for infusion
3. Sitting upright
4. Depending on the method of administration, put on a mask or mouthpiece and turn on the device
5. The procedure continues until the dose is completely used
6. The procedure time depends on the device used, on average 5-10 minutes.
7. At the end, the oral cavity is rinsed with water, you can also drink a glass of warm water.

Attention! After each use, the nebulizer must be washed with a non-aggressive detergent and dried. The remaining particles of the drug deteriorate when used repeatedly and can lead to complications.

Description and effect of the drug

Berodual is available in various forms, but most often the drug is used for inhalation administration. The effect of the medicine is due to two active components included in its composition:

1. Ipratorium bromide - promotes dilation of the bronchi, due to which there is an increase in exhalation within the first 10-15 minutes after using the drug. Moreover, the effect of the medicine increases within 1-2 hours and lasts for about six hours.
2. Fenoterol hydrobromide – relaxes the bronchioles of the respiratory system and eliminates bronchospastic reactions.

The combined effect of Berodual's two active substances is achieved even at low concentrations of these substances, which reduces the risk of side effects and makes the drug safe for use in pediatric practice.

During inhalation, berodual manifests its medicinal qualities directly in the lungs and bronchi, and therefore the therapeutic effect is achieved in an extremely short time

In addition to these components, the medicine contains auxiliary ingredients: water: preservatives, sodium chloride.

The components of the medicine complement each other, enhancing the therapeutic effect. As a result:

• Hypoxia is eliminated;
• The bronchi of small and medium caliber expand;
• Airway patency is restored;
• Exhalation volumes increase.

After inhalation with Berodual, the patient’s condition improves significantly: the cough is relieved, wheezing disappears, breathing improves, and the drainage function of the bronchi is restored.

Drug interactions

Beta-agonists, anticholinergic drugs and xanthine derivatives can enhance the bronchodilator effect after inhalation with Berodual. The simultaneous use of such medications may increase side effects. Taking beta-blockers can significantly weaken the bronchodilator effect of Berodual.

Digoxin increases the likelihood of developing arrhythmia due to hypokalemia caused by taking adrenergic agonists. When treating with Berodual, it is necessary to remember that there is a risk of developing hypokalemia. Its exacerbation can be enhanced by the simultaneous use of diuretics and xanthine derivatives with Berodual. This is especially true for those patients who suffer from complicated forms of pathologies of the inhalation organs.

Berodual is considered an effective drug that is widely used in the complex treatment of various pathologies of the respiratory system. Its use in accordance with the attached instructions allows you to relieve bronchospasm and alleviate the patient’s general condition.

Indications

The medicine is intended for the prevention and treatment of bronchospasm of various nature from 6 years of age. In consultation with your doctor, Berodual can be used at an earlier age, taking into account possible complications. Treatment of children under 6 years of age should be carried out under the supervision of a specialist, preferably in a hospital setting.

Indications:

• relief of an attack of bronchial asthma (for aerosol);
• prevention and treatment of bronchial asthma caused by exogenous and endogenous irritants (pollen, food, cold, etc.);
• obstructive pathology of the pulmonary system (emphysema, bronchiectasis, pneumosclerosis);
• asthma due to stress (triggered by physical activity);

Berodual is used to prepare the bronchi for the administration of drugs (antibiotics, mucolytics, glucocorticoids).

Reviews

Most patients and doctors respond positively to the drug. But it requires proper use and dose selection by a doctor. If this is not done, side effects may occur. The most typical reviews: Diana, 25 years old “I have had bronchial asthma since I was 16 years old. Bronchospasms develop especially often during and after viral infections. I always have Berotek with me, but I only use it for cramps or when I feel that they will appear soon. It’s a good drug, it suits me.”

Tatyana, 28 years old “I have bronchial asthma and I constantly relieve attacks with Berotek. My son recently fell ill; he is 5 years old. It started with a common acute respiratory infection, and then the first bronchospasm appeared. I sprayed him with Berotek, but the spasm got worse and I had to call an ambulance and go to the hospital. There they told me that it is better for children to take inhalations.”

Composition of the product and features of purpose

The effect of the drug in relieving bronchospasm is due to the presence of two main substances: fenoterol hydrobromide and ipratropium bromide monohydrate. They improve the functioning of the bronchi and increase the lumen, ensuring ease of breathing. The main substances are not hormonal. They act in combination, complementing each other.

The bronchodilator effect of Berodual is based on influencing the receptors of the nervous system without hormonal influence. The combined composition has a local effect due to the spraying of the drug and the entry of fine particles into the respiratory system. The effect is directly on the bronchi and lungs, which improves their patency and reduces obstruction.

Fenoterol relaxes the smooth muscles of the bronchi well and eliminates spasms caused by exposure to allergens, cold air, methacholyme or histamine. Patients who are professional athletes should take into account that treatment with drugs containing fenoterol may give a positive doping test result. Ipratropium bromide has a positive effect on the condition of the bronchi.

Thereby:

• wheezing is eliminated;
• breathing becomes easier;
• cough is eliminated;
• normal functioning of the bronchi is restored.

Both the active and auxiliary components are not hormonal, therefore Berodual itself is not a hormonal drug.

Release forms

The drug has the following release forms:

• a compact inhaler that you can carry with you;
• bottle with nebulizer solution.

Both of these release forms contain the same active ingredients. Those who believe that Berodual is a hormonal drug are wrong. Despite the fact that this remedy does not belong to the group of corticosteroids, it gives a good effect for severe cough, which is accompanied by bronchospasm.

Indications

Indications for use are the following diseases:

• chronic lung diseases;
• bronchial asthma;
• emphysema, etc.

Contraindications

Despite the fact that Berodual is not hormonal, there are quite a lot of contraindications for its use.

Among them are the following conditions:

• serious heart disease;
• pregnancy;
• intolerance to the ingredients of the product, etc.

When prescribing treatment, even not a hormonal drug, the doctor must take into account existing and past diseases, the age of the patient and the severity of the condition. Elevated body temperature is not a contraindication to prescribing the drug, since the procedure carried out using a nebulizer is not warming.

Side effects

In some cases, taking Berodual is accompanied by side effects. Most often, this situation occurs when the recommended dosage or duration of therapy is exceeded.

In case of an overdose of a non-hormonal bronchodilator, the patient may experience the following unpleasant symptoms:

• headache;
• nausea;
• dry mouth;
• vision problems and others.

Instructions for use of "Berodual" for inhalation in aerosol packaging

The pharmacy chain sells the drug in aerosol packaging. The instructions for using aerosol "Berodual" for inhalation strictly prohibit its administration to children under the age of 6 years.

The spray is offered in cans containing 20 single doses in a compressed state. This is approximately 10 ml of a solution ready for inhalation. For ease of use, the can is equipped with a dispenser and a mouthpiece through which the jet passes.

There is only one way to use the Berodual N spray - this is by spraying the recommended number of doses directly into the oral cavity. Opening the can and attempting to dilute its contents is strictly prohibited. The standard dosage for an adult and a child over 12 years of age is 2 single doses, for children from 6 to 12 years old - 1 single dose. If no pronounced therapeutic effect is observed after 10 minutes, then inhalation is repeated. More than 4 doses for an adult and 2 doses for a child should not be taken within 3 hours. If an attack of bronchospasm does not subside, then it is necessary to seek qualified medical help. A maximum of 8 single doses per day is allowed for an adult and 4 single doses for a child under 12 years of age.

Rules of use:

• take 2-3 deep breaths;
• Shake the can and remove the protective cap;
• at the deep inlet, make 1 aerosol injection;
• hold your breath after inhaling the drug for 1 second.

The opened can should be stored in the refrigerator for no longer than 1 month. As storage proceeds, the liquid evaporates and the concentration of the active substance increases. This may cause an overdose.

Analogs

There are times when you were prescribed Berodual, but it did not suit you. There may be several reasons: high price, contraindications or allergic reactions to components. Berodual can be replaced with drugs with a similar principle of action.

• Lazolvan – helps with dry cough and is a good expectorant. It can be used with Berodual in the form of complex therapy. In terms of price, both of these products are the same, but Lazolvan has a smaller list of contraindications.

• Intal plus - gives a good effect in the treatment of prolonged asthma. The main advantage is the anti-inflammatory and anti-allergic effects.

• Ambrobene is a good remedy for removing phlegm. This is one of the most effective mucolytics, which is prescribed during pregnancy and children. It can also be used in combination with Berodual.

• Beasten is a drug to maintain the patient’s optimal condition during remission. Prescribed for bronchial asthma and a number of other respiratory diseases. Relieves cough, thins mucus and relieves inflammation.
• Ditek is an inexpensive but effective remedy for the treatment of respiratory diseases.

All these medications have a similar principle of action to Berodual. But if a doctor prescribes this particular drug, you should not look for a replacement for it because of recommendations from friends and relatives.

Is it possible to overdose?

In case of an overdose, increased symptoms of side effects appear: paroxysmal acute pain in the heart, an increase or sharp decrease in blood pressure, heart rhythm disturbances, attacks of tachycardia, shortness of breath, etc. Face reddened, frightened.

Emergency help:

• stopping the use of the medicine;
• fresh air (open the window, vent);
• release from constricting clothing;
• taking any sedative (Valocardin, Validol, Seduxen);
• taking potassium (Asparkam, Panangin);
• calling an ambulance; if the condition does not improve, hospitalization.

As an antidote, medications from the group of beta-blockers are sometimes prescribed, which block the action of adrenaline and drugs with similar properties. These drugs include Atenolol, Betaxolol, Bisoprolol. But you should not use them independently without medical supervision as antidotes: they can cause bronchospasms. Sometimes overdose requires intensive care and even resuscitation measures.

pharmachologic effect

Thanks to the active substances contained in the drops, Berodual has a powerful bronchodilator effect. After using the product, it is possible to remove spasms from the smooth muscles of the respiratory organs, which helps prevent the occurrence of brochospasms when the body is exposed to various irritants (allergens, chemicals, viruses, cold air and others). In turn, phenalotrope eliminates swelling, preventing the accumulation of mucus in the bronchi.

Often inhalations using the medication in question are used among people suffering from bronchial asthma. It allows you to quickly and effectively eliminate spasms and asthma attacks, but does not disrupt gas metabolism in the body. The active components of the drug complement each other well, so the therapeutic effect in the patient becomes noticeable from the first days of using Berodual.

Interaction with other substances

The annotation contains no contraindications for the combined treatment of 3-year-old children with Berodual and other groups of drugs. To quickly relieve bronchial obstruction, basic therapy is often supplemented with inhalations with Lazolvan, Pulmicort, Miramistin or other antibiotics, mucolytics, and glucocorticosteroids.

Attention! The course of combined treatment is carried out under medical supervision. First, children are given inhalations of Berodual, then after 15–60 minutes another prescribed drug is administered by aerosol.

Method of use in a nebulizer

Inhaling Berodual using a nebulizer is convenient and safe. This method can be used even at elevated temperatures, since the steam is not warm.

Rules for using a nebulizer for inhalation with Berodual:

1. You must use a mask to protect your eyes from the medication vapors.
2. The number of inhalations per day is 2 procedures; they can be increased only with the permission of the attending physician.
3. Inhalation time depends on the speed of the nebulizer, but should not exceed 7 minutes.
4. If a person has difficulty breathing during the procedure, it is necessary to reduce the intensity of the steam supply. If the condition worsens, the procedure is interrupted.
5. You cannot go outside for 30 minutes after the procedure.
6. You can drink, eat food and other medications only half an hour after inhalation.

During the procedure, you must take deep, slow breaths, exhaling through your nose.

During the treatment of infectious diseases of the lungs and bronchi, half an hour after using inhalations with Berodual, it is recommended to carry out a similar procedure with a mucolytic. Most often, Lazolvan or Ambrobene are used for this.

Expected Result

In asthma, bronchospasm disappears immediately after inhalation. There may be no effect, then the procedure is repeated (after 5 minutes). If there is still no result, medical help is needed.

With bronchitis with obstruction, breathing becomes easier in the first 15 minutes. Wheezing and coughing may disappear completely or be less severe. If, after Berodual, inhalations with a mucolytic were done, the child begins to intensively produce sputum. During the first couple of hours, he may cough more often and/or more severely.

Side effect of inhalation

Berodual solution sometimes irritates mucous membranes and ligaments. The child may feel a sore throat (manifested by a cough). There may be urticaria, dizziness, hoarseness, blurred vision. Quincke's edema and anaphylactic reaction were also recorded. If any side effect occurs, a 3-year-old child is immediately taken to a doctor for examination and consultation.

Bottom line

Dosed aerosol for inhalation Berodual is a modern, highly effective non-hormonal remedy for relieving spasms of the respiratory tract. Compared to an inhalation solution, an aerosol can can be taken with you to work or school. The use of Berodual can quickly relieve spasms in the bronchi and facilitate the breathing process. However, it is prohibited to use the drug on your own without consulting a pulmonologist.

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Analogues of Berodual

Berodual is considered the most effective and affordable inhalation agent used in the treatment of infectious and inflammatory diseases of the lower respiratory tract. If the drug is intolerant or side effects occur, it can be replaced with analogues.

List of analogues:

1. Ditek. In addition to fenoterol, it contains disodium chromoglycate. Allowed from 6 years old, can be used to treat children 4-5 years old only in the minimum dosage. It is used as an effective replacement for hormone-containing drugs for the treatment of bronchial asthma. Can be used before sports and to prevent attacks during the period of allergen activity.
2. Biasten. The composition includes budesonite and salbutamol hemisuccinate. It is a prophylactic agent for inhalation for allergic reactions and bronchial asthma. Biastene is prohibited for use by children and people with a viral or bacterial respiratory tract infection. It does not help during an acute attack.
3. Ipraterol-aeronative. The composition of the drug is similar to Berodual. Available in the form of an aerosol for injecting liquid into the lungs and as a means for inhalation. Prohibited for use by people with severe cardiovascular diseases. Children are allowed only from 6 years old. If a child has high blood pressure, Ipraterol-aeronative can only be used from the age of 16.
4. Ultibro Breezhaler. A rather expensive drug, which contains glycopyrronium bromide and indacaterol. Children under 18 years of age are prohibited from using. It is the best analogue of Berodual for people with diseases of the cardiovascular system. It is used to prevent and eliminate narrowing of the bronchi in diseases with obstructive phenomena in the bronchi.

special instructions

Berodual for inhalation (the instructions for use contain instructions that it is necessary to avoid getting the drug into the eyes) can cause severe burning, pain in the eyes and changes in the visual outlines of objects.

Pregnant women should stop taking the drug at 38-41 weeks. When contractions occur, fenoterol weakens labor and can cause serious complications.

In case of hereditary systemic intestinal diseases, taking the drug can cause constipation.

Athletes should avoid using birodual before competitions. Elements of the drug may negatively affect a doping test. After inhalation, it is better to refrain from driving a car and performing dangerous work for several hours. Berodual affects the clarity of vision and can cause dizziness.

How to use the drug

Before using Berodual, you must carefully read the instructions for use. If you are using a pocket inhaler, then first remove the cap from it, do one single spray , and then tightly wrap your lips around the nozzle and spray one dose while inhaling.

If treatment is carried out with Berodual solution, then it is diluted with saline solution before inhalation. For adults, pour 20-40 drops of medicinal solution and 2 ml of saline solution. For the treatment of children, 10-20 drops are prescribed, which are diluted with 3 ml of saline solution.

Inhalations through a nebulizer should not last longer than 15 minutes . Breathing should be calm, inhale through the mouth and exhale through the nose. After the procedure, the remaining medication is poured out, and the mask and solution container are not only washed, but also treated with an antiseptic.

For inhalation with a nebulizer, a mask is selected according to size; it should fit snugly to the face.

If the doctor has prescribed Berodual inhalations for bronchial asthma or bronchitis, you should not think for a long time whether to be treated with this remedy or not. The drug is not a hormone and does not have any effect on the hormonal balance in the body, so it can be safely used if there are no contraindications.

Source: pulmono.ru

Concomitant use with other medications

Being a non-hormonal bronchodilator, Berodual is effective both on its own and when taken together with other drugs prescribed for cough. For example, with Ambroxol.

Is Berodual a hormonal drug? No is not . The possibility of using it in one course with corticosteroids is determined by the doctor. Consultation with your doctor is also required when using additional drugs for treatment.

In the treatment of severe obstructive diseases of the respiratory system, the joint administration of the non-hormonal Berodual with Pulmicort (hormonal powder for inhalation) can lead to hypokalemia. Despite the fact that the first drug well expands the lumen of the bronchi, and the second is a highly effective hormonal drug, their combined use has not been described. Inhalations with Pulmicort, which has a local effect, as well as with Berodual, can be carried out even at elevated body temperatures.

In combination with certain medications, taking Berodual can lead to serious side effects and delay the recovery process (for example, with theophylline). When combined with beta-blockers, a decrease in the effect of Berodual will be observed. In this regard, self-medication with such a drug is not acceptable. It is especially important to strictly follow prescriptions for obstructive forms of respiratory tract diseases.

Interaction

When prescribing Berodual, you must tell your doctor about chronic diseases, since the drug may negatively affect the functioning of other medications. Berodual weakens the effect of beta blockers.

Berodual enhances the effect:

• xalin derivatives;
• cromoglicic acid;
• MAO inhibitors;
• some antidepressants.

The use of the drug simultaneously with general anesthesia requires additional monitoring by physicians. The combination of medications can negatively affect the functioning of the cardiovascular system.

Side effects and contraindications

A pediatrician may prescribe inhalation of Berodual to a child if there are no contraindications to the use of the product.

The drug is prohibited for the following pathologies:

• disruption of the functioning of the main cardiac muscle due to an increase in heart size;
• pathological heart diseases, including congenital ones;
• frequent heart contractions;
• presence of elevated temperature;
• the presence of acute infectious diseases;
• intolerance or allergic reaction to elements of the product;
• increased intraocular pressure;
• the presence of blood streaks in the sputum;
• impaired brain function due to poor circulation;
• pathological changes in the thyroid gland;
• genetic disorder of lung function.

If you have diabetes, the drug is used only under the supervision of a pediatrician.

These restrictions were introduced due to the likelihood of side effects during inhalation:

• severe dryness of the oral mucosa and larynx;
• disruption of muscle contractility due to the removal of potassium from the body under the influence of berodual;
• dizziness and headaches;
• increased heart rate and increased blood pressure;
• feeling of nausea, possible vomiting with the release of masses;
• bowel dysfunction (diarrhea or constipation) and difficulty urinating;
• prolonged cough with a large amount of sputum;
• irritation of the skin with an itchy rash;
• loss of strength and feeling of general weakness;
• change in behavior (irritation, anxiety).

If side effects are detected, the pediatrician adjusts the dosage and course of therapy or replaces the medication.