Lidaza: instructions for use in injections, features of the product, its pros and cons

Lidase is a drug that can have a targeted effect on enzyme reactions in the human body.

In particular, enzymatic preparations have proven themselves to be the most effective drugs in the treatment of restrictions on normal joint mobility, inflammatory processes with complications such as necrosis or scarring of tissue, as well as thrombosis and a number of other pathologies.

Lidase is available in the form of lyophilisate, solution for injection and inhalation. For special indications, the doctor can give a prescription for vaginal or rectal suppositories with Lidaza. This drug is not produced in tablets.

Pharmacological properties

The active component of the drug is obtained from living cells of the seminal glands of large horned animals. The therapeutic effect of Lidase is aimed at the pathogenic factor - increased levels of hyaluronic acid. The chemical gives connective tissue cementing properties, increases fluid viscosity and fiber density.

An excess of acid has a negative effect on the body: it contributes to the modification of tissues and the formation of scars. Lidase suppresses its activity, breaks it down into its component parts (glucosamine, glucuric acid) and minimizes the viscosity of the intercellular matrix.

The biological effect of hyaluronidase is a reversible process. When the active agent is removed from tissue structures, the properties of hyaluronic acid are restored.

Indications for use

Lidaza is one of the drugs widely used in the treatment of many pathologies from different fields of medicine. Indications for use are:

• myocardial infarction;
• burn, postoperative, traumatic scars;
• ulcers;
• chronic tenosynovitis;
• superficial hematomas;
• airway obstruction;
• scleroderma, a type of skin disease.

Lidaza is prescribed for chronic prostatitis complicated by diffuse or focal lesions.

Therapeutic effect

Lidase regulates the production of substances responsible for the nutrition of tissue fibers. Acting at the cellular level the drug:

• increases vascular permeability;
• increases collagen synthesis;
• removes excess fluid from extracellular spaces;
• eliminates pain in the affected area;
• reduces limitation of passive movements in joints;
• reduces the number of pathological stimuli;
• reduces treatment and rehabilitation time;
• restores structural changes and functional abilities of organs.

Lidase improves the bioavailability of other drugs and increases the analgesic effect of general anesthetics.

Interaction with other drugs

Lidaza combines well with various medications, as it has an auxiliary value in the treatment of diseases. The instructions say that the drug enhances the effect of local anesthetics and improves the absorption of medications administered intramuscularly or subcutaneously. Suppositories are not combined with Phenytoin and Furosemide, and benzodiazepines are not used.

The instructions do not say anything about the compatibility of the drug with alcohol. But when drinking alcoholic beverages during treatment, they interfere with a speedy recovery.

Areas of application for Lidase

Due to its properties, Lidaza is widely used in various fields of medical activity.

Indications for use.

Gynecology:

• formation of adhesions after suffering inflammatory processes;
• prevention of adhesions due to surgery;
• the initial stage of hyperplasia - an increase in the size of an organ or neoplasm;
• hormonal dysfunction of the female reproductive system;
• pelvic floor neuralgia;
• acute inflammatory diseases of the abdominal wall;
• obstruction of the fallopian tubes;
• abnormalities in the development of the uterus.

Urology:

• prostatitis – inflammation of the prostate gland;
• interstitial cystitis - painful bladder syndrome;
• chronic cystitis.

Ophthalmology:

• retinopathy – damage to the visual organs, leading to disruption of the blood supply to the retina, atrophy of the optic nerve;
• hemophthalmos - damage to retinal vessels, hemorrhage into the vitreous body or into the space around it.

Dermatology:

• scleroderma - thickening of connective tissue on the skin and internal organs;
• skin diseases accompanied by the formation of ulcers;
• soft tissue hematomas;
• scar formations of various etiologies.

How does Lidaza work for prostatitis?

The prostate gland is a glandular organ consisting of two lobules and having many ducts inside. During the inflammatory process, exudate begins to be produced in the tissues, local blood circulation is disrupted, and therefore edema develops.

They prevent the normal outflow of prostate secretions, and in the case of purulent processes, they prevent the pus from leaving the prostate gland. The organ increases in size and compresses the urethra, hence the problem of urination.

At the site of the inflammatory process, connective tissue – a scar – develops over time. At this point, the prostate loses its functions, which causes hormonal imbalances, erectile dysfunction and other problems. Obviously, many manifestations of prostatitis can be avoided if the growth of connective tissue is stopped or slowed down. This is exactly the effect that Lidaza has.

The drug is made from an extract from bovine testes and contains hyaluronidase. This enzyme is capable of breaking down (destroying) hyaluronic acid, the main “building material” of connective tissue. As a result of this effect, the following positive changes are noted in the body:

1. Permeability in blood vessels and tissues increases, nutrients and medicinal substances penetrate faster and in greater quantities.
2. Due to the improved movement of fluids, the area and volume of edema is reduced, including in the prostate gland.
3. Scars, having lost their main material, soften and then collapse.

Lidaza is not able to affect the original cause of prostatitis, but it can reverse some pathological processes. This ensures a speedy recovery and return of the sick man to his usual and comfortable lifestyle.

Lidaza in combination treatment

Subcutaneous administration of Lidase is carried out in patients with injuries to the plexuses and peripheral nerves: brachial plexitis, mononeuritis.

The drug is used in the form of inhalations in the treatment of tuberculosis. The procedures help increase the concentration of antibacterial substances in the area of ​​inflammation.

The product is included in complex treatment:

• allergic rhinitis;
• arachnoiditis - serous lesion of the arachnoid membrane of the spinal cord or brain;
• acute myocardial infarction.

For preventive purposes, the substance is used to prepare the female reproductive system for in vitro fertilization and at the preparatory stage of pregnancy planning.

In cosmetology, Lidaza is used to treat skin fibrosis after liposuction and hypertrophic nodes. With the help of hyaluronidase, they prevent the risk of developing necrosis, impaired vascular patency, and a decrease in blood supply to any part of the body. The drug eliminates the consequences of excessive administration of hyaluronic acid - focal inflammation of the subcutaneous tissue.

Causes of prostatitis and specific treatment

Experts, in most cases, associate the appearance of this disease with inflammation of the prostate gland.
The reasons why this symptom occurs can be varied. Thus, a long-term absence of sexual intercourse and a low level of physical activity lead to stagnant processes in the reproductive system. In this regard, blood microcirculation is disrupted, which causes inflammation of the prostate gland. In addition, the causes of the disease can be infections or mental disorders. At the same time, the patient’s health worsens, weakness appears, and immunity decreases. All this can lead to inflammation of the prostate gland and the development of prostatitis.

In order to get rid of the disease once and for all, many experts recommend various sets of medications. The first group of agents has antiviral and antimicrobial properties. Other medications help eliminate congestion and restore blood microcirculation.

Lidaza in physiotherapy

Pathological deviations of the female genital area are caused by impaired blood flow. In this case, electrophoresis with Lidase is used in gynecological practice. The method allows you to increase blood circulation in the treated area and painlessly introduce the substance into the site of inflammation. Positive dynamics in treatment can be achieved in a short period of time.

• The procedure is carried out using two pads soaked in a hyaluronidase solution. The interaction of electrodes of different polarities connected to them creates an electromagnetic field. Powerful electrical impulses break down the drug at the molecular level, increasing its activity and bioavailability. This allows you to significantly reduce the dosage of the pharmacological product.
• Physiotherapy is carried out using the abdominal method. The drug is administered into the entrance to the female genital organs. One of the electrodes is placed there, while the other is fixed outside.

Electrophoresis with Lidase increases the elasticity of scar joints. This helps solve many problems without surgery and long-term rehabilitation. The procedure reduces the risk of undesirable consequences from the digestive organs, liver and kidneys to a minimum. With oral administration of drugs and intramuscular injection there is no such guarantee.

The method has proven itself well in the treatment of rheumatoid arthritis, characterized by chronic inflammation of the joints.

Lidaza has the most pronounced effect at the initial stage of pathological changes, or during the recovery period after elimination of the acute inflammatory process.

Vacation conditions and price

The average cost of Lidaz (ampoules 64 UE, 10 pcs.) in Moscow is 315 rubles. Requires a prescription.

The shelf life of the powder is 2 years from the date of its manufacture. After preparing the solution, it must be used within an hour.

The instructions for use recommend storing unopened Lidaza ampoules in a dark place, protected from light, at an air temperature no higher than 15º C.

In medicine there is the concept of “drug synonym”. This means that the product contains an active substance identical to the original. In a broad sense, an analogue is considered a pharmacological product that has the same therapeutic effect, but may have a different active ingredient. To make your own choice, it is better to use synonyms. This will allow you to replace the drug prescribed by your doctor with minimal risk.

If necessary, Lidaza injections or suppositories can be replaced with an analogue in terms of therapeutic effect - these are the following drugs:

1. Hyaluronidase;
2. Lidaza-M;
3. Biohyal;
4. Ronidaza.

When choosing analogues, it is important to understand that the instructions for use of Lidaz, the price and reviews of drugs with similar effects do not apply. It is important to consult a doctor and not change the drug yourself.

Store in a place protected from light, at a temperature not exceeding 15 °C. Keep away from children. Shelf life – 2 years.

What do the reviews say?

Reviews of Lidaza injections indicate that the drug has a therapeutic effect in any case, even if the therapy is accompanied by some side effects. People often complain that the first few procedures bring discomfort and even pain, but later these symptoms go away and doctors say that this is quite normal.

In gynecology, Lidaza injections and suppositories help relieve women of many problems, therefore, despite the doubts of some people, the drug is actively prescribed by gynecologists and has an effective effect in the treatment of many diseases.

Contraindications

Contraindications to the use of Lidaza are:

• individual intolerance;
• oncological diseases;
• active form of tuberculosis;
• fresh hemorrhages;
• pulmonary hemorrhage or sputum with blood clots in it;
• respiratory failure.

Before starting a therapeutic course, it is advisable to conduct an intradermal test to determine the individual tolerance of the components.

Concomitant use of Lidase with estrogens, female sex hormone steroids, is not recommended. Intramuscular medicinal injections into sites of localization of infectious pathogens and tumors are contraindicated.

The incompatibility of the simultaneous use of Lidase with Furosemide, Phenetoin and anticonvulsants has been proven.

Reviews

Valery, 38 years old: I took a course for prostatitis several times, but it was not possible to be completely cured. Until I saw another urologist, who immediately included Lidaza in the prescription, and after a couple of weeks I felt its effect. The nagging pain in the groin decreased, a feeling of relief appeared, when I told the doctor about this, he explained that the swelling had gone down.

Stanislav, 49 years old: I used to think that Lidaza was not an important drug, which, as they say, only caused extra holes in the soft spot. It seemed to me that antibiotics were enough. But recently there was a relapse of prostatitis again, I was injected without Lidaza, and was very surprised, not feeling the expected relief. Then I had to repeat the treatment later. I really regret my mistake and refusal of the doctor’s recommendations.

Gleb, 56 years old: From my own experience, I know that nothing can replace complex treatment if you have prostatitis. No matter how many anti-inflammatory drugs and antibiotics are prescribed, until Lidaza normalizes blood circulation, a complete cure will not occur. I tried it on myself in several ways, of course, the most unpleasant was insertion into the urethra, but the doctor usually insisted on this, persuading that this is how the medicine is best absorbed.

Alexander, 31 years old: I had prostatitis, I was receiving treatment, but I understand that I don’t feel 100%. And it’s impossible to have children. Now I’m undergoing another treatment, the doctor recommended that I add Lidaza and described all its benefits. Perhaps this is self-hypnosis, but it seems to me that it is gradually becoming easier and my condition is improving. I'm looking forward to finishing the course.

Side effects

The drug is well tolerated by the biological system, but in some cases the effect of the pharmacological product may be determined by:

• the appearance of blisters, rashes, itching;
• abnormal redness of the skin;
• angioedema;
• anaphylactoid reactions;
• ventricular fibrillation (rare exceptions).

The drug should be used in accordance with the doses recommended by a specialist. In case of overdose, the following symptoms occur: chills, nausea, involuntary eruption of stomach contents, loss of balance, rapid heartbeat, decreased blood pressure, local edema.

Lidaza (injections): instructions for use

When Lidaza is prescribed, instructions for use, injections, how to dilute the drug - the doctor should know all this. When using Lidaza in ampoules (vials), the following are taken into account:

• indications and contraindications;
• interaction with other medications and ethanol;
• allergy history;
• physiological state;
• presence of concomitant pathology;
• possible undesirable consequences.

Dosage regimen and treatment regimen

If there are scars on the skin, inject 1 ml of solution every day or every other day. The course of therapy involves 10-20 injections. If nerves and nerve plexuses are damaged due to trauma, the medicine is administered subcutaneously, after diluting the lyophilisate with a solution of procaine. Injections are performed every other day. The maximum number of injections per course of treatment is 15.

In case of damage to the organ of vision, Lidase is administered subconjunctivally (under the conjunctiva of the eye) 0.3 ml (one-third of the ampoule) or parabulbarly (into the tissue of the lower eyelid) 0.5 ml. It is possible to administer the drug using electrophoresis. For pulmonary tuberculosis, the drug is administered daily. The number of injections is 20-25. The solution can also be used to treat affected skin. The bandage is applied to the skin for 15-18 hours for 1-2 months.

How to dilute Lidaza for intramuscular injections

To dilute Lidase, use a 0.5% solution of Procaine or 0.9% Novocaine.

How to administer the drug

The medicine is administered subcutaneously and intramuscularly.

When performing subcutaneous injections you must:

1. Check the integrity of the bottles and the expiration date of the drug.
2. Prepare the necessary equipment (cotton balls, alcohol, medicine, disposable sterile gloves, syringe with needle).
3. Achieve a trusting relationship with the patient.
4. Dilute the lyophilisate and draw the solution into a syringe.
5. Release the air from the syringe (no bubbles should remain).
6. Treat the skin in the shoulder area.
7. Make a skin fold and insert the needle at a 45º angle under the skin.
8. Inject the medicine and remove the needle.
9. Apply a cotton ball to the injection site.

With the intramuscular route of administration, the injection site is the gluteus maximus muscle. The needle is inserted into the upper outer quadrant perpendicular to the skin deep into the muscle. Injections into the butt and shoulder are best left to a specialist.

Side effects and overdose

When using Lidase for injection, undesirable effects are rarely observed. The drug is well tolerated by patients. Only sometimes allergic (itching, rashes, tissue swelling, redness) and local reactions in the form of skin irritation in the injection area are observed. Most side effects are temporary. Symptoms disappear within a few hours.

The following signs indicate an overdose of Lidase:

• nausea;
• vomit;
• chills;
• rapid heartbeat (more than 80 beats per minute);
• drop in blood pressure (hypotension);
• urticaria (rash in the form of blisters, accompanied by severe itching);
• local tissue swelling;
• rashes like erythema (red spots);
• dizziness.

Help with overdose involves reducing the frequency of injections or completely stopping injections, using glucocorticosteroids, adrenergic agonists (Adrenaline solution) and antihistamines (Zyrtec, Zodac, Cetrin or Loratadine). Adrenaline allows you to increase blood pressure if it decreases, and corticosteroids and histamine receptor blockers fight allergic reactions and inflammation.

The role of enzyme therapy

The combination of the three processes described above (formation of purulent discharge, replacement with scar tissue and sclerosis of the prostate gland) makes it justified and necessary to use drugs from the group of enzymes, in particular, a drug such as Lidaza, for the treatment of prostatitis.

Brief information about the drug

Lidase is a medicine from the group of enzyme agents, the main active ingredient of which is hyaluronidase - that is, enzymes that can break down any acidic mucopolysaccharides. The hyaluronidase used to produce this medicine is obtained from the testes of male livestock.

Lidase provides a therapeutic effect due to its ability to change the structure of hyaluronic acid, which is part of all connective tissue of the human body. Hyaluronic acid is an acidic mucopolysaccharide, so hyaluronidase, which is part of lidase, reacts well with it. By breaking hyaluronic acid into smaller fragments, lidase disrupts the strength and density of connective tissue inclusions, making them more permeable and accessible to the penetration of various substances, including drugs.

This drug is produced in powder form for the preparation of solutions for both external and internal (parenteral) use.

The main contraindications to the use of this medication are:

• hypersensitivity to the components of the drug;
• infectious and inflammatory diseases in the acute stage;
• history of bleeding;
• oncological processes.

Allergic reactions are usually noted as side effects.

Use of Lidase for prostatitis

Considering that a contraindication to treatment with Lidaza is the presence of an infectious-inflammatory process in the acute stage, prostatitis can be treated with this drug only in the remission stage.

Prostatitis in remission is usually characterized by the presence of scarring or sclerotic changes. Lidaza allows you to eliminate them or make them less pronounced, thereby helping to restore microcirculation and increase tissue permeability for drugs, including etiotropic ones.

With chronic prostatitis of stages 3-4, in addition to changes in the morphological characteristics of prostate tissue, there is a disruption of blood coagulation processes (thickening of the blood) and a decrease in the sensitivity of cells to the action of proteolytic enzymes (substances that break down the bonds between protein molecules). Therefore, the process of active sclerosis and scarring begins. Lidase allows you to compensate for low sensitivity to enzymes and promotes the dissolution of altered tissues and the prevention of the formation of new defects.

In addition, this drug affects the purulent discharge accumulated in the prostate cells, making it more liquid and simplifying the process of removing pus out.

Clinical trials prove that in the treatment of chronic prostatitis, enzymes can achieve the following results:

1. Reduce pathologically increased sexual desire.
2. Reduce the severity of genitourinary disorders.
3. Speed ​​up the healing process.

The usual course of treatment with Lidase in combination with etiotropic, immunostimulating, sedative therapy, as well as vitamin therapy and physiotherapy, is 20 daily subcutaneous injections of the drug at a dose of 64 thousand Action Units. For stage 3-4 prostatitis, the duration of this course can be increased.

The combination of Lidase treatment with prostate massage is effective, since the mechanical effect on the prostate tissue promotes the outflow of pathological secretions and the softening of dense scarred or sclerotic areas.

KakBik.ru

Diseases of the prostate gland bring many negative changes to a man’s full life: pain in the pelvic area, problems with urination, lack of a full sex life, the risk of developing impotence, as well as periodic discomfort in the pelvic area.

The development of inflammatory processes in the prostate complicates the normal life of a man

To get rid of the symptoms listed above, it is necessary not only to diagnose and eliminate the cause that led to the development of the disease, but also to completely restore the normal functioning of all organs and systems. This requires the use of complex therapy, which helps to stabilize the activity of the entire organism as a whole.

Specifics of treatment for prostatitis

The main and most common causes due to which prostatitis occurs - a disease of the prostate gland, expressed in the development of the inflammatory process, can be called the following:

• Lack of systematic sexual activity for a long time, as well as sufficient physical activity. These aspects, both in combination and independently, over time lead to the development of pathogenic congestive processes in the pelvic area, that is, a violation of blood microcirculation. In most cases, it is these factors that lead to the manifestation of the main symptoms of prostatitis.
• Infectious diseases of other body systems, as well as those classified as sexually transmitted diseases. Due to the fact that all organs and systems are interconnected in a certain way, after a virus affects a certain organ, a similar pathology can also develop in the pelvic area.
• The disease can also be caused by certain disorders at the mental level, deterioration of general well-being, expressed in a decrease in the body’s immune forces, taking certain medications over a long period of time and intoxication of the body, which appears against the background of prolonged abuse of alcoholic beverages.

The drug Lidaza helps eliminate stagnation and improve blood flow

To eliminate the true cause that led to the development of pathological processes, treatment of pelvic inflammation includes not only the use of drugs that have antimicrobial and antiviral effects, but also drugs that eliminate congestion and help restore blood microcirculation. Medicines of this kind used as additional therapy include Lidaza.

Composition, properties, description

The drug Lidaza is produced in the form of a powdery substance intended for the preparation of sterile solutions. The drug obtained in this way is used for injection intravenously or intramuscularly.

The main component of the drug is hyaluronidase, a substance obtained from the testes of male cattle. This ingredient has the following properties: penetrating into the connective tissues of the body, it has a splitting effect on hyaluronic acid, making it less viscous.

Thanks to this effect, the tissues of the human body become more receptive and permeable to the absorption of active substances contained in drugs used as antibacterial therapy. Also, excess fluid is removed from the body, swelling and congestion are reduced.

Lidaza is used for intravenous injections

Pharmacological action of the drug

Lidaza for prostatitis is used exclusively as an adjuvant therapy. The specificity of the disease is as follows: inflammatory processes in the prostate gland are provoked, or were initially provoked by a violation of blood microcirculation in the pelvic organs.

The use of Lidaza helps eliminate pathological phenomena, restores blood circulation and the normal functioning of all organs and systems as a whole. In addition, the drug helps ensure that drugs with targeted antibacterial action are better absorbed by the body and enter the connective tissues in the required concentration.

The main advantage of the drug is that the drug is intended for administration directly to the area of ​​localization of inflammation, that is, the negative impact on the digestive organs is minimized.

Lidaza is used only as an adjuvant

Indications for use

Lidaza is used to treat prostatitis, both in chronic form and in the acute and initial stages of the disease. The main indications for the use of the drug are the following:

• Lack of positive dynamics during the treatment of inflammatory processes and stagnation in the pelvic area.
• Improving the absorption of drugs used as the main therapy aimed at eliminating the symptoms of prostatitis.
• Elimination of stagnation processes in the organs of the reproductive and excretory systems, restoration of blood circulation and normal functioning of all organs.
• Elimination of pathological sexual excitability caused by taking medications or dysfunctions of the reproductive system.
• Targeted impact on the elimination of pathological phenomena that contribute to the development of disorders of the excretory and reproductive systems.

Lidaza is prescribed to improve the absorption of other drugs

Contraindications and precautions

Despite the fact that Lidaza is a drug of animal origin, that is, its main components are partly similar to the human body, there are a number of contraindications, the presence of which excludes the possibility of using the drug. These include the following:

• Hypersensitivity, risk of developing negative reactions to any substance included in the drug.
• Respiratory diseases occurring in varying degrees of severity.
• The presence of benign or malignant pathological neoplasms at any stage of the disease.

Instructions for use

Lidaza is used in the treatment of inflammatory diseases of the pelvic organs as an adjuvant. Typically, a single dose of the drug administered into muscle tissue is 1 mg per day. If indicated, the concentration of the active substance can be reduced to 1 mg over two days.

Compliance with dosage is an important rule when using Lidaza

When treating prostatitis, the medication should be taken for 10-15 days. The final course is calculated by the doctor based on the individual characteristics of the patient and his current condition.

The drug is injected directly into the area of ​​modified tissues or the lesion through injection.

How prostatitis is treated - the following video will tell you about it:

urogenital.ru

Longidaza is a drug that is usually used to treat scars left after surgery.

But it turns out that Longidaza can also help with prostatitis!

According to the results of the experiments, the effectiveness of treatment with this drug was 82%. The result is impressive, so it’s worth talking about this drug separately.

Tizol with lidase

In addition to injections, suppositories and for electrophoresis, lidase is used to prepare tizol-based ointments. The product promotes rapid restoration of the skin, resorption of scars, and is effective for hematomas. The drug is manufactured according to a prescription in industrial pharmacies. Composition of the ointment:

• 128 UE lidase;
• 10 g Tizol.

You can prepare an ointment based on lidase yourself. Take two ampoules of lidase, add two drops of boiled water to each. The contents of the ampoules are mixed with 10 g of Tizol. After obtaining a homogeneous consistency, the product is ready for use. The ointment can be stored in a dark place for up to 2 years.

Tizol with lidase is used in the form of dressings. A gauze pad is soaked in the ointment, applied to the affected area and secured with an adhesive plaster or bandage. Applications are changed daily, the course of treatment ranges from two weeks to two months. 14-15 sessions alternate with 3-4 days off.

Analogs

Drug synonyms are calculated according to the international standard, taking into account the mechanism of action and the main substance in the composition. Analogues of Lidaza are:

1. Containing hyaluronidase: Ronidaza, Actinogial, Hyaluronidase, Lidaza-M, Lyraza.
2. Mechanism of action: "Arnigel" for topical use.
3. Homeopathic remedies in the form of drops: “Shwer-Hel”, “Berberis-Gomakkord”, “Galium-Hel”.
4. Solution for injection: “Hepar compositum”, “Coenzyme”, “Mucosa”, “Momordica”, “Pulsatilla”, “Ubiquinone”.
5. Film-coated tablets: “Strumel T”, “Gomeovox”, “Kokkulin”, “Gomeostres”.
6. Solution for oral administration "Dimephosphone".
7. Product for external use in the form of gel "Carmolis".
8. Herbal collection "Ingafitol" number 1 and 2.
9. Solution for topical use: “Selenium”, “Mardil”.

Important! Drugs with a mechanism of action similar to Lidaza are inferior in effectiveness to the licensed drug.

Treatment effectiveness

By enhancing blood microcirculation in the treated area, a positive effect is achieved after just a few sessions. A set of physiotherapeutic procedures promotes:

• reducing treatment time;
• elimination of painful symptoms;
• accelerating the process of tissue regeneration;
• reduction of pathogenic irritants in the diseased organ;
• removing excess fluid;
• production of biologically active substances;
• decreased muscle tone.

Galvanization is an excellent way to produce substances that enhance the activity of the immune system and restore the body's protective functions.

Lidaza suppositories and tablets

The use of suppositories for the treatment of prostatitis is due to the effectiveness of the drug, which has:

• immunomodulatory properties;
• anti-edema effect;
• anti-inflammatory effect;
• antioxidant property.

Suppositories are quickly absorbed and have an antibacterial effect.
Suppositories help remove toxins from the rectum. Rectal administration allows you to quickly reach the lesion, while not having a negative effect on the liver.

The course of therapy is determined individually for each patient, depending on the stage and form of prostatitis. On average, the duration of treatment is from 15 to 30 days.

The medicine is administered while lying on your side, after a cleansing enema. If the use of the drug is long-term, it is recommended to take a break (7 days) and then resume treatment.

After rectal use at the first appointments the following is noted:

• decrease in prostate size;
• elimination of swelling;
• restoration of reproductive function;
• no pain when urinating.

The analogue "Homeovox" is available in the form of a lozenge; it is not effective in the treatment of prostatitis.

General information about drugs

Hyaluronidase and azoximer bromide are the active ingredients of Longidase. It is quite difficult to find an analogue of the drug with the same active ingredients, since it does not exist. There are only a few drugs that are similar in their effects. These include the drug "Ronidaza" and an analogue of injections "Longidaza" - the drug "Lidaza" for injection. The latter remedy is quite popular. It is often recommended instead of the drug Longidaza. An analogue - the drug "Lidaza" - cannot be a complete substitute for this medication, because it contains only one common component - hyaluronidase.

Longidaza

Longidaza is considered a more modern analogue of Lidaza. However, this drug has a longer lasting effect. In addition to the proteolytic (absorbable) effect, it also combines antioxidant, immunomodulatory and anti-inflammatory properties.

Recent clinical studies have shown that Longidaza does not have a negative effect on normal connective tissue, but only destroys pathologically altered (scars).

In most cases, the medicine is quite well tolerated.

Indications

Considering the pharmacological effect of the drug, Longidaza has found wide use in various fields of medicine, including gynecology, surgery, urology, dermatology, pulmonology, etc. We list the main indications that are associated with the prevention and treatment of adhesions in the pelvis:

• Gynecological surgical interventions or manipulations.
• Artificial termination of pregnancy.
• Adhesions that have developed inside the uterus.
• Chronic pathology of the internal genital organs of an inflammatory nature (adnexitis, salpingitis and
• etc.).
• Obstruction of the fallopian tubes.
• Chronic endometriosis.

Contraindications

Like its analogue, Longidaza may not be prescribed to all categories of patients. Do not forget that the appropriateness of using any medicinal product or method is determined by the attending physician. In what cases is this drug contraindicated for use:

• Hypersensitivity to the components of the drug.
• Tumors.
• The period of bearing a child.
• Patients under 12 years of age.

Longidaza should be used with extreme caution in people with serious kidney, lung or heart problems.

Adverse reactions

The results of many clinical studies have shown that adverse reactions develop quite rarely. However, the development of an allergy cannot be ruled out if the patient has an increased sensitivity to the active substances of the drug, which he forgot to inform his doctor about.

If an allergic reaction occurs, you must immediately stop administering the drug and carry out symptomatic therapy.

special instructions

If the therapeutic dosage of the drug is observed, Longidaza does not worsen the course of the postoperative period. In addition, it is worth noting that it in no way interferes with the restoration of bone tissue. Can be used in complex therapy of diseases that are accompanied by pathological proliferation of connective tissue. With renal or pulmonary failure, it is recommended to use no more than once every 7 days.

Pregnancy is a contraindication, since there are no clinical data on studies in this category of patients. However, the drug is not known to cause fetal abnormalities. When used simultaneously with other drugs (for example, salicylates, hydrocortisone, estrogens, etc.), a decrease in the effectiveness of the active substance Longidase is observed. Dispensed in pharmacies without a doctor's prescription. Before purchasing, it is recommended to consult with a specialist.

When choosing any medicine, there are three main points to consider: effectiveness, safety and availability.

Release form

The medicine is produced in the form of a lyophilisate. A solution for injection is prepared from it. The drug can be used topically. The pharmacy sells glass bottles in 5 ml packaging. They are carefully closed with a rubber stopper, as well as a rolled aluminum cap. The concentration of the drug is 64 units.

One package contains 10 bottles. The manufacturer provides printed instructions for use. The package includes a solvent. This is a bottle containing 5 ml of 0.9% sodium chloride solution.