Review of effective suppositories for the treatment of ovarian cysts


How do Longidaza suppositories help with ovarian cysts?

Longidaza is a medicine produced as an injection solution, and it is also produced as suppositories, and this is the form that is mainly used in gynecology. The advantage of the medicine is that it affects only the affected tissues, without affecting healthy ones. With the help of suppositories, toxins can be removed from the body and those breakdown products that arise during treatment.

Women have many unnecessary problems if they had to undergo an artificial termination of pregnancy or if infectious and inflammatory processes have arisen and become chronic. All this affects in the future if you really want to have a child. But persistent infertility may occur due to numerous adhesions or untreated inflammatory processes. So Longidaza comes to the rescue, restoring female fertility. One of the most common diseases affecting women is ovarian cysts. Moreover, age, profession, habits do not play a role at all, and if earlier, when there were no such progressive research methods, it was believed that a cyst could only form in women belonging to the childbearing age group, then it turned out that both young and mature women Those who have crossed the threshold of 50 years can carry a cyst within themselves.

This disease is dangerous because it has very negative consequences if it is not neutralized in time. Its presence in the body leads to the fact that over time the following may occur:

  • internal bleeding;
  • infertility;
  • tissue death in the genitals;
  • degeneration into oncological formations on the ovaries and many other unexpected and unpleasant surprises.

If a cyst has been detected, the doctor prescribes a full examination, both gynecological and necessary medical, and then treatment follows. In order to rid a woman of a cyst, an integrated approach is needed, which means that several medications and various measures with a different spectrum of action will be required. This includes medications that contain the effect of:

  • anti-inflammatory;
  • hormone;
  • immunomodeling.

And in this case, for ovarian cysts, Longidaza is prescribed more and more often, as it fits perfectly into the treatment due to its effective properties and excellent tolerability.

This is an enzyme medicine that contains properties such as:

  • anti-inflammatory;
  • antioxidant;
  • proteolytic;
  • immunomodeling.

But the medicine also helps when it is necessary to treat urological diseases and even during therapy prescribed for tuberculosis. When a patient needs recovery after surgery, Longidaza also comes to the rescue.

Source proyaichniki.ru

Longidase is an enzyme preparation that has proteolytic, immunomodulatory and anti-inflammatory effects. In gynecology, it is prescribed for the prevention and treatment of adhesions in the pelvic organs after various manipulations and surgical operations. The use of the drug can reduce the risk of developing adhesions and preserve the reproductive health of women.

Longidaza suppositories for ovarian cysts are prescribed as an adjuvant during the rehabilitation stage. It is justified to use the drug after surgery to prevent the formation of adhesions. Longidaza does not promote resorption of ovarian cysts and is not used instead of surgery. The use of an enzyme cannot be a substitute for a full-fledged operation.

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Ovarian cyst is a widespread gynecological disease that can be diagnosed in absolutely any woman, regardless of age, race and occupation. For quite a long time, it was believed that ovarian cysts are a disease of women exclusively of childbearing age. Today, the situation has changed dramatically: this gynecological disease is equally often diagnosed in young girls and women over 50 years of age.

Ovarian cyst is one of the most dangerous diseases of the female genital area. It is dangerous due to its consequences, among which are internal bleeding, tissue death of the genital organs, infertility, and oncological tumors of the ovaries and other organs. It becomes clear that at the first suspicion of an ovarian cyst, you should undergo a full medical and gynecological examination and immediately begin a course of treatment.

The effectiveness of treatment for ovarian cysts is based on an integrated approach to solving this gynecological pathology - this means that to eliminate the disease, not one, but several medications and therapeutic measures with a different spectrum of actions are used. Most often, the course of treatment for the disease consists of the use of anti-inflammatory, hormonal, and immunomodulatory medications. Longidaza suppositories show excellent results in the treatment of ovarian cysts - this drug has become widespread due to its high efficiency and good tolerability.

Description of the drug and release form

Longidaza is an enzyme drug with a pronounced proteolytic, anti-inflammatory, antioxidant and immunomodulatory effect. This medication contains two main active components: hyaluronidase and azoximer bromide. Today, Longidaza suppositories have found wide use in the treatment of numerous gynecological diseases accompanied by connective tissue hyperplasia. In addition to gynecology, the medicine is also used in the treatment of urological diseases, tuberculosis, and during the recovery period after surgery.

What effect do Longidaza suppositories have on the body?

  1. This medication helps improve the permeability and nutrition of body tissues.
  2. The drug improves the mobility and elasticity of joints, normalizes the condition of the skin after injuries.
  3. Longidaza promotes rapid resorption of scars, adhesions, reduction of swelling, and clearly exhibits antifibrotic properties.

The medicine is produced in the form of vaginal suppositories of light yellow color, having a traditional oblong shape. One Longidase suppository contains 3000 IU of the main active component - hyaluronidase.

Recommended dosage

The drug is available in the form of suppositories for vaginal administration. When using Longidase in the treatment of ovarian cysts, it is recommended to adhere to the dosage prescribed by your doctor. For mild forms of ovarian cysts, doctors recommend using one suppository once every three days; for moderate forms of the disease, the drug is administered every other day. For women with severe forms of the disease, daily use of Longidaza suppositories may be prescribed.

Suppositories are administered in a comfortable lying position. The best option would be to use the medication immediately before bedtime. If this is not possible, then you can use the drug at any other time of the day, but after inserting the suppository you should lie down for 15 - 20 minutes.

The duration of treatment usually does not exceed 10 applications. Depending on the stage, severity and extent of the disease, the course of treatment can be increased to 20 procedures.

Contraindications to the use of Longidase

This drug is not prescribed in a number of cases:

  1. Longidaza suppositories are not used to treat children and adolescents under 12 years of age.
  2. Contraindications to the use of the drug are pregnancy and lactation. If it is necessary to use the drug in the postpartum period, breastfeeding should be abandoned.
  3. The medicine is not prescribed to patients with cancer.
  4. Longidaza suppositories are not used if a woman is hypersensitive to the components of the drug.
  5. In the presence of renal dysfunction, the use of the drug is possible only under the supervision of a physician. In this case, patients are not recommended to use suppositories more than once every 7 days.

Side effects and overdose

Longidaza suppositories are in most cases well tolerated by the female body and do not cause side effects. It is extremely rare for a woman using this drug to treat an ovarian cyst to experience allergic reactions on the skin - redness, rash, itching, peeling. Most often, the causes of such a reaction are the increased sensitivity of the female body to one or more components of the medication. In such a situation, adverse reactions do not require treatment, but in case of serious side effects of the drug, you should immediately contact your doctor - you may need to discontinue the drug and replace it with another medication with a similar principle of action.

In very rare cases, allergic reactions may be local in nature - that is, they may directly affect the site of administration of the drug. At the first signs of redness, swelling, and discomfort in the genitals, it is recommended to stop using suppositories.

Longidaza suppositories are used vaginally, which almost completely eliminates the possibility of drug overdose. To date, there are no known cases of overdose of this medication in medicine.

Interaction with other drugs

When using Longidaza suppositories in combination with other drugs, it should be remembered that such interaction may have a negative impact on the effectiveness of the drug and, accordingly, the success of treatment. You should not combine suppositories with antihistamines, estrogens, or cortisone - they significantly reduce the effectiveness of Longidase.

It is not recommended to take suppositories simultaneously with diuretics, as well as Furosemide and its derivatives. This drug interaction significantly enhances the diuretic effect of diuretics.

Important information

When using Longidaza suppositories in the treatment of ovarian cysts, you should pay attention to some special instructions.

The drug is not used during pregnancy and breastfeeding. It is also not recommended to use suppositories if you are planning a pregnancy in the very near future. Doctors advise starting planning and preparation for pregnancy at least 2 months after finishing the Longidase course.

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General information about the drug

The active ingredient of Longidase is bovhyaluronidase azoximer. Until recently, the drug was produced only in the form of an injection solution. The injection of the drug was effective, but not very convenient, and so the pharmaceutical industry offered the drug in suppositories for administration into the rectum and vagina. The injection form of the medication can be used if suppositories are intolerant.

Longidaza suppositories contain 3000 IU of active ingredient each. These are light yellow torpedo-shaped suppositories. Their uneven coloring is allowed. There is a slight smell of cocoa. Suppositories should be stored at a temperature from 2° C to 15° C in a dry place protected from light. Do not use the medicine after the expiration date.

Indications for the use of Longidase for ovarian cysts

The use of the drug is justified after surgical treatment. The main task of Longidase is to prevent the formation of adhesions. The use of the medicine helps prevent the development of adhesive disease and its complications:

  • The appearance of chronic pain in the pelvic area;
  • Infertility as a result of obstruction of the fallopian tubes or blockage of the ovary by adhesions;
  • An ectopic pregnancy occurs when the lumen of the fallopian tubes is partially blocked.

The formation of adhesions - connective tissue cords between the uterus, its appendages, peritoneum and other pelvic organs - occurs after surgery. The likelihood of their occurrence is significantly higher during laparotomy, since during abdominal surgery significant damage to internal organs occurs, as well as their drying out when exposed to air. Such cords can cover the ovarian capsule and prevent the release of the egg into the abdominal cavity. Adhesions also form in the lumen of the fallopian tubes, which leads to their obstruction. Longidaza is prescribed to prevent these complications.

The use of Longidase does not promote the resorption of ovarian cysts. The enzyme does not affect hormonal levels and does not lead to regression of the lesion.

The use of an enzyme preparation is possible after removal of any type of cyst or true ovarian tumor. Its use in other situations is also permitted. In gynecology, this drug is prescribed after an abortion, diagnostic curettage of the uterus, surgery on the pelvic or abdominal organs. It is practiced to use Longidase for polycystic ovary syndrome after resection or cauterization.

Indications for the use of suppositories for ovarian cysts

Since one of the factors causing cysts is inflammation of the pelvic organs, anti-inflammatory suppositories are used to treat it. They consist of enzymes that dissolve adhesions, blood clots, pus, and blood clots. They are administered rectally, the dose and duration of treatment is determined by the doctor individually.

In case of hormonal imbalances (often excess estrogen, lack of progesterone), hormonal vaginal suppositories are used. Progesterone is the main active ingredient, a hormone that normalizes hormonal levels, which leads to a reduction in cystic formations and reduces the risk of complications.

To restore the vaginal microflora after treating inflammation with antibiotics and suppositories, suppositories with lactobacilli are used vaginally.

In case of immune system failures, which can also lead to cystic formations, immunomodulators are prescribed in the form of rectal suppositories.

[9], [10], [11]

How does the medicine work in the postoperative period?

  • Enzyme activity of prolonged action. The drug promotes protein breakdown and prevents the formation of adhesions;
  • Antioxidant action. Longidaza protects tissues from the aggressive effects of free radicals;
  • Immunomodulatory effect. The product helps maintain local and general immunity, reduces the risk of infection;
  • Anti-inflammatory effect. The use of the drug leads to a reduction in inflammation in the pelvic tissues.

The effect of the drug lasts for 20 days. All this time, Longidaza exerts its influence on the body and prevents the development of adhesive disease. After its administration, tissue swelling is eliminated and inflammation subsides, fluid flow in the intercellular space is restored and the elasticity of connective tissue increases. This reduces the risk of formation of adhesions both in the uterine cavity and between the pelvic organs.

Numerous studies have shown that Longidaza does not affect normal connective tissue. The drug causes changes only in those areas where the formation of adhesions is potentially possible. The use of an enzyme agent in the dosages specified by the doctor does not interfere with the course of the postoperative period and does not slow down tissue healing.

Types of candles

To treat ovarian cysts, suppositories with different actions are used.

Will Duphaston help with ovarian cysts? Read the article.

Hormonal

The cause of the cyst is often a hormonal imbalance in the patient. With the help of a suppository with hormones, it is possible to normalize a woman’s condition and achieve regression of the tumor.

The hormonal drug Utrozhestan is widely used to treat cysts. Its active ingredient, progesterone, restores hormonal levels and promotes the formation of normal endometrium. Helps prevent tumor recurrence.

The size of the formation decreases after several applications, and at the end of the course the cyst is completely reabsorbed.

Do not use if there is a risk of thrombosis or heart disease.

Side effects include cycle disruption, bleeding between periods, and headache. The duration of the course is determined by the attending physician.

Anti-inflammatory

Often, formations on the ovaries are adjacent to the inflammatory process in the pelvis. Suppositories with antibacterial and anti-inflammatory effects contain enzymes that eliminate the pathological process .

Longidaza. The drug promotes the breakdown of proteins, thereby achieving an anti-inflammatory and decongestant effect. It even treats chronic inflammation in the pelvis. This is a unique product that has no analogues.

Do not use during pregnancy or for malignant tumors. Side effects include an individual allergic reaction.

Voltaren. Diclofenac-based suppositories. Its action is anti-inflammatory, analgesic and mild antipyretic. Not prescribed during pregnancy, stomach ulcers, severe pathology of the heart and kidneys. Side effects are: allergies, abdominal pain, indigestion, headaches.

Terzhinan. Combined drug with antibacterial and anti-inflammatory action. Effective in the treatment of candidiasis. Restores vaginal pH. Used during pregnancy in the 3rd semester. There are almost no contraindications, with the exception of individual intolerance.

Indomethacin. Belongs to the group of non-steroidal anti-inflammatory drugs. It also has antipyretic and analgesic properties. Do not use for vaginal infections.

Indomethacin suppositories have a fairly wide range of contraindications: stomach ulcers, arterial hypertension, heart disease, liver disease, kidney disease, epilepsy, tendency to form blood clots, pregnancy. They can also cause side effects in the form of: dizziness, nausea, diarrhea, insomnia, increased blood pressure, swelling.

Ichthyols. Suppositories have a positive effect on the vaginal mucosa, promoting healing. They also relieve inflammation in the ovaries. They have an antiseptic and bactericidal effect. Allowed during pregnancy. Side effects include an allergic reaction.

Do not use simultaneously with iodine-containing drugs or if you are hypersensitive.

Scheme of use of the drug in gynecology

Longidaz suppositories must be placed strictly according to the instructions:

  • Suppositories are inserted into the rectum or vagina. It is forbidden to take the medicine orally;
  • To use suppositories vaginally, you need to lie on your back and bend your knees. The suppository is inserted deep into the vagina. You can place suppositories from a squatting position with your legs spread wide apart;
  • For rectal administration, you need to lie on your back or side and bend your knees. The suppository is inserted into the rectum.

For the treatment of ovarian cysts, the drug is prescribed once a day at night. The course of therapy lasts 10-20 days. The duration of treatment is determined by the doctor. It is recommended to begin therapy in the first days after surgery to get the maximum effect from using the enzyme agent.

The use of the drug is allowed during menstruation, but it is better to administer the suppositories rectally on menstruation days. There is no need to interrupt the course of treatment.

Recommended dosage

The drug is available in the form of suppositories for vaginal administration. When using Longidase in the treatment of ovarian cysts, it is recommended to adhere to the dosage prescribed by your doctor. For mild forms of ovarian cysts, doctors recommend using one suppository once every three days; for moderate forms of the disease, the drug is administered every other day. For women with severe forms of the disease, daily use of Longidaza suppositories may be prescribed.

Suppositories are administered in a comfortable lying position. The best option would be to use the medication immediately before bedtime. If this is not possible, then you can use the drug at any other time of the day, but after inserting the suppository you should lie down for 15 - 20 minutes.

The duration of treatment usually does not exceed 10 applications. Depending on the stage, severity and extent of the disease, the course of treatment can be increased to 20 procedures.

Side effects after using the product

Based on reviews from women, we can conclude that Longidaza is quite well tolerated and rarely causes unwanted reactions. Even if minor discomfort occurs in the form of a burning sensation at the site of insertion of the suppositories, women usually manage to complete the course of therapy. Other side effects that occur less frequently include:

  • Itching, swelling and redness of the area around the anus;
  • Itching and discomfort in the vagina;
  • The appearance of an allergic rash on the skin at the injection site.

If symptoms increase, you should stop using the drug and consult a doctor.

Contraindications, or when Longidaza is prohibited

Candles are not used in the following situations:

  • Children's age up to 12 years. There is no data on the safety of the drug in children and adolescents;
  • Hypersensitivity to the components of the drug and a previous allergic reaction;
  • Fresh bleeding, including vaginal;
  • Malignant neoplasms of any location;
  • Acute renal failure;
  • Pregnancy and lactation (there is no data on the safety of the drug).

In case of severe renal impairment, the medicine is prescribed once a week.

Side effects and contraindications

In some cases it is possible:

  • allergies,
  • skin rashes.

The drug is not prescribed:

  • up to 12 years;
  • in case of individual intolerance to the components of the product;
  • for acute infectious diseases;
  • with hemoptysis;
  • for oncology;
  • with severe renal failure;
  • during pregnancy.

During the lactation period, Longidaza can only be used under the strict supervision of a physician .

Features of application

In the postoperative period, Longidaza can be prescribed simultaneously with antibiotics, antifungal and antiviral agents. The use of these drugs does not interfere with the action of the enzyme.

It is not recommended to take Longidaza together with estrogens, antihistamines and salicylates in large doses. These agents reduce the proteolytic activity of the enzyme.

If you miss a dose, do not administer a double dose. It is recommended to continue using the product at the usual dosage according to the regimen prescribed by your doctor.

Cancellation of the drug is carried out simultaneously. There is no need to gradually reduce the dose. According to indications, a second course of therapy can be carried out in a month.

Longidase analogs

A complete analogue of the drug has not been developed. There are other remedies with similar effects. An example is Lidaza, an enzyme preparation based on hyaluronidase. It is available in the form of an injection solution. It is administered intramuscularly or subcutaneously. The list of indications for this remedy does not differ from that for Longidaza. In gynecology, Lidaza is used less frequently.

Other medications can be prescribed as symptomatic therapy for ovarian cysts - ichthyol suppositories, suppositories with sea buckthorn, propolis, indomethacin. They have a different effect and cannot be considered as analogues of Longidase. The listed drugs have a pronounced anti-inflammatory effect, but have little effect on the development of the adhesive process.

Ichthyol candles and their features

You can often hear that excellent results in the treatment of cysts can be achieved with the help of ichthyol. This substance is frighteningly black in color. It is obtained from shale resins. The unique composition includes more than 10% natural sulfur. The use of the drug guarantees the elimination of pathological processes in the pelvic organs. Ichthyol suppositories have been used in gynecology for diseases of the female reproductive system for more than a century. Despite the fact that the modern pharmaceutical market is rich in other, more modern, drugs, these suppositories hold the leading position in sales.

Ichthyol suppositories for ovarian cysts are inserted into the rectum. Vaginal use can lead to serious problems and complications. After 3-4 rectal injections, you can notice the following effect:

  • the source of inflammation is eliminated;
  • blood circulation is normalized;
  • pain syndrome decreases.

Before administering suppositories, you need to cleanse the intestines. Place candles three times a day. The duration of therapy is determined by the doctor.

The drug cannot be combined with drugs based on iodine, heavy metal salts and alkaloids.

Ichthyol rarely causes adverse reactions. In exceptional cases, itching and rashes on the body are possible.

Reviews of the drug Longidaza

Reviews from women who used the drug in the postoperative period are mostly positive. Longidaza helped many of them avoid adhesive disease. Most patients report good tolerance to suppositories. Usually, when inserting suppositories, no pain or burning is observed. Less commonly, a local allergic reaction to the components of the drug occurs, manifested in the form of itching and other discomfort.

Longidaza has taken its rightful place in the practice of gynecologists. The drug is actively prescribed after operations, including the removal of an ovarian cyst. The recovery period in women who have used this medicine is easier and is less likely to be accompanied by the development of complications. Its use promotes the resorption of adhesions that form after surgery and prevents their reappearance.

The use of Longidase has a beneficial effect on a woman's reproductive health. The use of this remedy helps prevent infertility associated with the development of adhesions. After surgery and a course of treatment with Longidaza, many women manage to successfully conceive, carry and give birth to a child.

Source mioma911.ru

Ovarian cyst is considered one of the most common diseases in gynecology. It can occur at any age. According to the World Health Organization, 10% of women suffer from this pathology.

In gynecology, a cyst is a formation on the ovary in the form of a bubble, due to which it can increase many times over. As a result, the natural rhythms of the body are disrupted and the monthly cycle suffers. Every tenth woman exhibits uncharacteristic symptoms: pain, swelling, emotional instability.

The most dangerous are the long-term consequences that result from neglect and delayed treatment. Among them are purulent inflammation, sepsis, cancer, and infertility. Therefore, it is especially important when diagnosing a cyst not to delay treatment, but to address the health condition as early as possible.

There are many approaches to the treatment of ovarian cysts, among which everyone will choose the most suitable and convenient for themselves. The central place is occupied by pharmacological therapy, the means of which are drugs with different mechanisms of action. When treating the disease, painkillers and hormonal agents are used that affect inflammation itself and even immunity. Longidaza suppositories for ovarian cysts are used quite often and have received good reviews from both doctors and patients themselves.

Anti-inflammatory vaginal suppositories

Anti-inflammatory suppositories for ovarian cysts help achieve a quick recovery. As a result, both the left and right ovaries are restored, and this organ begins to function correctly again. A full course of medication is required, which can last a month, sometimes less, depending on the severity of the disease.

The Indomethacin suppository has a pronounced anti-inflammatory effect and helps remove the infectious form of the disease. The most effective treatment method can only be prescribed by a doctor. The specialist will give a detailed answer to the patient’s question about how to treat an ovarian cyst. If pregnancy occurs, therapy is carried out under the strict supervision of a doctor.

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Suppositories with ichthyol for ovarian cysts

Gynecology involves the use of suppositories that contain ichthyol. Recently, gynecology is increasingly using ichthyol suppositories to treat the disease. These products cannot be inserted directly into the vagina - the suppository provokes severe irritation of the mucous membrane, which can cause damage to the uterus.

Ichthyol suppositories are widely used in gynecology; their price is low, so they are quite affordable. This remedy has a reparative, antibacterial and anti-inflammatory effect. Ichthyol suppositories for the treatment of neoplasms should be prescribed by a doctor. The drug is used rectally, so it can help not only normalize hormonal levels, but also cure hemorrhoids.

Ichthyol type of suppositories must be used every day - three times. Before using the drug, be sure to study the attached instructions. During treatment, it is necessary to use gynecological pads to avoid contamination of underwear. To enhance the positive effect of the drug, it is recommended to have a bowel movement before using it, or you can do a cleansing enema.

Suppositories with indomethacin in gynecology

Most gynecological diseases are accompanied by severe pain, so indomethacin is prescribed to relieve inflammation. The dosage and duration of treatment is established taking into account the patient’s condition and the course of the disease. The indomethacin component in the drug is aimed at stopping the formation of substances that have a stimulating effect on nerve endings, thereby relieving even the most severe pain.

There is a suspension and synthesis of various substances involved in the inflammatory process. Due to the form of release of vaginal suppositories, such a drug will be quickly absorbed, and relief will come in the near future. It is important to undergo a full treatment course, after which sexual activity is restored. As a rule, the pain syndrome is completely relieved in about 12-16 minutes.

Suppositories with celandine for ovarian cysts

More and more experts recommend treating ovarian cysts using a drug with celandine. The drug is relatively inexpensive and is sold not only in stores, it can be ordered and purchased at an online pharmacy, where the price of the product is much lower. You can make the medicine yourself using celandine. Reviews from women who have experienced the effects of this drug indicate their high effectiveness.

Indications for use

Longidaza suppositories can be prescribed for a wide variety of conditions. They can be taken from the age of 12, separately and together with other drugs for the treatment of diseases associated with connective tissue injury.

In gynecology, Longidaza is used for diseases such as:

  • adhesions in the uterus and ovaries during chronic inflammation and as a result of surgical gynecological interventions;
  • infertility as a result of obstruction of the fallopian tubes;
  • chronic inflammation of the endometrium;
  • ovarian cysts, including follicular, luteal, hemorrhagic, endometrial and paraovarian.

In addition to gynecology, Longidraza is used in the following areas of medicine:

  1. In urology - for the treatment of chronic inflammation of the prostate and interstitial cystitis.
  2. In surgery - for resolving scars, adhesions, and wounds that do not heal for a long time.
  3. In dermatology and cosmetology - for the treatment of autoimmune connective tissue diseases and various types of scars.
  4. In pneumonology and phthisiology in the treatment of tuberculosis and other lung pathologies.
  5. In orthopedics for arthrosis, atritis and hematomas.

Longidase is used to enhance the effect of antibiotics and local anesthetics in all of the above areas.

Mechanism of action in the disease

Longidaza has long-lasting enzymatic activity. It has an antioxidant, immunomodulatory and moderate anti-inflammatory effect.

The main active ingredient of the drug is hyaluronidase. By binding to mucopolysaccharide compounds found in the connective tissue of the cyst, it reduces inflammation, normalizes tissue and cellular response, increases humoral immunity and the body's resistance to infection.

Due to the fact that when hyaluronidase enters the body, it is included in a complex with mucopolysaccharides, the duration of its action and the maximum severity of the effect increase many times. According to the information provided by the manufacturer, as part of Longidase, this enzyme remains active for 20 days, while by itself it is only effective for one day.

In addition, the complex, consisting of hyaluronidase and a carrier, attracts to itself the compounds that are required for the growth of connective tissue in the cyst, as a result of which it stops increasing in volume and gradually resolves.

As a result of numerous clinical trials in which biochemical, immunological and histological indicators were studied, it was proven that Longidaza does not affect healthy connective tissue, but only affects the altered one, which consists of formations, including ovarian cysts.

Longidaza penetrates well into the organs and tissues of the body, including the ovaries.

Vaginal suppositories with lactobacilli

If the correct microflora of the vagina is disrupted, vaginal suppositories are prescribed, which contain a unique lactobacilli. With regular use of these drugs, a positive therapeutic effect is achieved. The suppository is inserted directly into the vagina, as shown in the photo in the attached instructions. There is a significant increase in the protective capabilities of the mucous membrane, metabolic processes are accelerated, and pathogenic flora is prevented from entering the body.

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Reception scheme

The frequency of use of Longidase depends primarily on the age and severity of the disease. For mild forms, 1 suppository is prescribed once every 3 days. In this case, the total course is 10 administrations, after which, if necessary, support therapy can be prescribed - 1 suppository once a week for 3-4 months.

For moderately severe conditions, it is recommended to use the product every other day.

In severe cases, suppositories are administered every day. In this case, the course of treatment can reach up to 20 administrations.

It is recommended to administer the suppositories while lying down, before going to bed. If it is impossible to insert a candle at this time, you should choose the time of use in such a way that you can be in a horizontal position for at least 15 minutes.

If you miss an injection, you should wait until the next use and follow the standard regimen given in the instructions for use or as prescribed by your doctor. There is no need to double the dose.

Revitalizing candles

After the completed course of treatment, it is necessary to restore the vaginal microflora, which is helped by vaginal suppositories with lactobacilli: Laktonorm, Acelakt, Vigalkt. Their use is possible only as prescribed by a doctor.

In addition, the woman needs to restore local immunity. Therefore, the doctor may prescribe Kipferon suppositories, which have an immunomodulatory effect.

Suppositories with propolis can not only act on pathogenic elements, but also restore the female body. The substances in the composition have a positive effect on the mucous membrane, anesthetizing and restoring the area; reduce the negative effects of medications taken orally. Beeswax has few contraindications and causes virtually no side effects.

Contraindications

Cases where taking Longidaza is inadmissible include:

  • pulmonary hemorrhage;
  • oncological diseases;
  • kidney disease in the acute phase;
  • hypersensitivity to individual components of the drug;
  • acute infectious inflammation in the area of ​​drug administration.

This drug should not be used by children under 12 years of age, pregnant women and nursing mothers. In this case, another medication with the same effect should be selected.

With caution, no more than once a week, Longidaza can be used by people who have had kidney disease and bleeding from the lungs in the past.

Women who drive a car and are engaged in activities that require increased concentration can use Longidaza. This drug does not affect consciousness or reaction speed.

Contraindications to the use of Longidase

This drug is not prescribed in a number of cases:

  1. Longidaza suppositories are not used to treat children and adolescents under 12 years of age.
  2. Contraindications to the use of the drug are pregnancy and lactation. If it is necessary to use the drug in the postpartum period, breastfeeding should be abandoned.
  3. The medicine is not prescribed to patients with cancer.
  4. Longidaza suppositories are not used if a woman is hypersensitive to the components of the drug.
  5. In the presence of renal dysfunction, the use of the drug is possible only under the supervision of a physician. In this case, patients are not recommended to use suppositories more than once every 7 days.

Side effects

Side effects of Longidase are extremely rare. According to the information provided by the manufacturer of the drug, the frequency of undesirable effects is 0.001%, which is one of the best indicators in the segment of drugs for the treatment of ovarian cysts.

In rare cases, allergic reactions such as itching, redness and swelling near the application area may occur. This is due to the individual sensitivity of the body to the components that make up the drug. In this case, you need to contact your doctor and choose another medicine with a similar mechanism of action.

An overdose of the drug is manifested by chills, increased body temperature, dizziness and a drop in blood pressure. In this case, you need to stop administering the medication and consult a doctor to receive adequate symptomatic therapy.

Since the drug is used vaginally and rectally, the possibility of overdose is extremely low. So far, not a single case of overdose with Longidaza suppositories has been recorded.

Drug interactions

Longidaza suppositories can be used in combination with antibacterial, antiviral and antifungal drugs. Possible combined use with bronchodilators, cytostatics and moderate doses of glucocorticoids.

However, when prescribed with other drugs, it should be taken into account that a noticeable increase in the effect of both drugs is possible.

The effect of Longidase can be reduced to a critical level if the drug is used in conjunction with large doses of cortisone, ACTH (adrenocorticotropic hormone), estrogens and other female sex hormones, antiallergic drugs, acetylsalicylic acid derivatives and sodium salicylate.

It is not recommended to use this drug together with diuretics (especially Furosemide), Phenytoin and benzodiazepines, as well as with drugs that contain them.

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